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HC-Pro

Euk-Vir

Impatiens_flower_break_virus

HC-Pro__YP_009255234_HC-Pro__Impatiens_flower_break_virus__2170135

Identity

Accession:: YP_009255234_HC-Pro ↗
Protein ID:: HC-Pro
Kingdom:: euk

Quality

82.7 mean pLDDT

Taxonomy

Orthornavirae› Pisuviricota› Stelpaviricetes› Patatavirales› Potyviridae› Potyvirus› Impatiens_flower_break_virus

TaxID: 2170135

Cluster

View cluster (80 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 33-106

PDB

Domain cluster: rep: HC-Pro__YP_009252411__Tobacco_mosqueado_virus__1792583__D31-64_66-104

CATH (31)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
4pxoA02	1.20.1050.10	Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 ›	0.63	56.0	4.65e-01	100.0%	68.7%
2l3lA01	1.20.58.1250	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Tubulin Binding Cofactor C, N-terminal domain	0.61	50.0	4.49e-01	100.0%	64.2%
4oydB00	1.10.132.20	Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor	0.61	56.0	4.75e-01	100.0%	88.9%
2kjgA00	1.20.120.970	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) ›	0.61	43.0	3.95e-01	94.6%	55.6%
1evsA00	1.20.1250.10	Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; ›	0.60	51.0	3.95e-01	94.6%	60.7%
3lewA01	1.25.40.390	Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat ›	0.59	50.0	3.37e-01	100.0%	53.7%
2r0rB00	1.10.225.10	Mainly Alpha › Orthogonal Bundle › NK-Lysin › Saposin-like	0.58	42.0	4.21e-01	94.6%	74.4%
1oshA00	1.10.565.10	Mainly Alpha › Orthogonal Bundle › Retinoid X Receptor › Retinoid X Receptor	0.58	46.0	3.39e-01	89.2%	87.5%
2pbiA02	1.10.1240.60	Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 ›	0.58	42.0	3.78e-01	75.7%	56.4%
4nqwB00	1.10.10.1320	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Anti-sigma factor, zinc-finger domain	0.58	36.0	3.66e-01	89.2%	63.0%
4hwhE00	1.20.58.120	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain	0.58	51.0	4.85e-01	100.0%	87.5%
4gmqA00	1.10.8.840	Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Ribosome-associated complex head domain	0.57	42.0	3.95e-01	87.8%	63.0%
3cqxC00	1.20.58.890	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 ›	0.56	39.0	3.85e-01	70.3%	66.7%
2qr4A01	1.20.140.70	Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Oligopeptidase f, N-terminal domain	0.56	47.0	3.78e-01	97.3%	54.5%
2q9rA01	1.20.1590.10	Mainly Alpha › Up-down Bundle › YP_001051499.1 fold like › YP_001051499.1 domain like	0.55	49.0	3.58e-01	100.0%	90.8%
1gt0D00	1.10.30.10	Mainly Alpha › Orthogonal Bundle › DNA Binding (I), subunit A › High mobility group box domain	0.54	40.0	3.96e-01	81.1%	89.9%
3nowA01	1.25.10.10	Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant	0.54	46.0	3.01e-01	98.6%	26.5%
7l4aA01	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.54	45.0	3.35e-01	100.0%	74.0%
3m9vA03	1.20.140.10	Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3	0.53	43.0	3.50e-01	93.2%	70.1%
3tjmA02	1.10.1470.20	Mainly Alpha › Orthogonal Bundle › Protein Yjbj; Chain: A; › Fatty acid synthase; domain 2	0.53	36.0	3.47e-01	86.5%	57.8%
1br0A00	1.20.58.70	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 ›	0.53	46.0	3.96e-01	100.0%	86.7%
7craA02	1.20.58.1480	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 ›	0.53	37.0	3.48e-01	73.0%	75.0%
6x6nA01	1.20.120.260	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Virulence factor YopE uncharacterised domain	0.52	38.0	3.34e-01	78.4%	90.6%
3dpjF00	1.10.357.10	Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2	0.52	45.0	3.42e-01	100.0%	45.2%
2ycdA02	1.20.1050.10	Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 ›	0.52	45.0	3.93e-01	100.0%	71.8%
4epzA00	1.25.40.810	Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › UpxZ	0.52	44.0	3.49e-01	95.9%	64.3%
2uxwA02	1.10.540.10	Mainly Alpha › Orthogonal Bundle › Butyryl-Coa Dehydrogenase, subunit A; domain 1 › Acyl-CoA dehydrogenase/oxidase, N-terminal domain	0.52	45.0	3.87e-01	100.0%	63.6%
2e2oA02	3.30.420.40	Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain	0.51	42.0	3.39e-01	97.3%	75.0%
4lwsB00	1.10.287.1060	Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like	0.51	38.0	3.68e-01	82.4%	71.6%
3fppA03	6.10.140.1990	Special › Helix non-globular › Helix Hairpins ›	0.50	37.0	3.58e-01	81.1%	92.0%
4hehA01	1.10.1240.10	Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › Methionine synthase domain	0.50	37.0	3.66e-01	90.5%	73.5%

ECOD (19)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
4128901	109.4.1.158 ↗	alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › ERAP1_C	0.70	49.0	3.32e-01	93.2%	20.0%
3522050	109.3.1.131 ↗	alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › INT_SG_DDX_CT_C	0.66	44.0	4.48e-01	97.3%	70.3%
4322551	604.23.1.0 ↗	alpha bundles › Spectrin repeat-like › Sbi complement-binding domain › Sbi complement-binding domain	0.65	44.0	4.85e-01	98.6%	94.5%
3239152	611.3.1.1 ↗	alpha bundles › N-cbl like › Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 › Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 › Med26	0.62	43.0	4.16e-01	97.3%	63.5%
59125	109.1.1.0 ↗	alpha superhelices › Repetitive alpha hairpins › Glutathione S-transferase (GST)-C › Glutathione S-transferase (GST)-C	0.61	54.0	4.54e-01	100.0%	65.4%
4221874	109.4.1.0 ↗	alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat	0.58	49.0	3.44e-01	97.3%	30.0%
2134378	11.1.1.153 ↗	beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › ERAP1_C	0.58	40.0	3.93e-01	97.3%	64.7%
3801688	604.1.1.0 ↗	alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat	0.58	50.0	4.54e-01	100.0%	86.7%
3598215	601.1.1.0 ↗	alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin	0.57	49.0	3.86e-01	100.0%	70.0%
3749294	605.1.1.177 ↗	alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › PF27917	0.57	43.0	4.00e-01	81.1%	77.9%
3252622	604.1.1.0 ↗	alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat	0.57	49.0	4.60e-01	100.0%	87.4%
3563679	604.1.1.0 ↗	alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat	0.56	48.0	4.38e-01	100.0%	82.9%
3898556	101.1.1.0 ↗	alpha arrays › HTH › HTH › Three-helical HTH	0.54	31.0	3.48e-01	91.9%	78.0%
4074492	7051.1.1.1 ↗	alpha arrays › C-terminal domain of Npl4 › C-terminal domain of Npl4 › C-terminal domain of Npl4 › NPL4	0.53	39.0	3.57e-01	77.0%	93.7%
4942015	141.1.1.3 ↗	alpha bundles › Terpenoid synthases › Terpenoid synthases › Terpenoid synthases › UbiA	0.53	44.0	3.11e-01	100.0%	83.2%
3530379	604.1.1.0 ↗	alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat	0.53	41.0	3.64e-01	87.8%	82.6%
3597736	192.29.1.0 ↗	alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding)	0.52	38.0	3.68e-01	77.0%	68.2%
3455776	109.23.1.4 ↗	alpha superhelices › Repetitive alpha hairpins › C-terminal domain in vacuolar protein sorting-associated protein 54 › C-terminal domain in vacuolar protein sorting-associated protein 54 › TPR_PATROL1	0.52	41.0	4.18e-01	94.6%	96.0%
3597512	101.1.1.0 ↗	alpha arrays › HTH › HTH › Three-helical HTH	0.51	38.0	3.82e-01	90.5%	78.7%

D2 medium residues 112-171

PDB

Domain cluster: rep: HC-Pro_protein__YP_006405405__Basella_rugose_mosaic_virus__373398__D110-165

D3 medium residues 272-457

PDB

Domain cluster: rep: HC-Pro_protein__YP_006590094__Chinese_yam_necrotic_mosaic_virus__128818__D95-261

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF00851.25 best	Peptidase_C6	249.5	9.40e-74	98.9%	41.4%