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HC-Pro_protein
Euk-VirScallion_mosaic_virus
HC-Pro_protein__NP_734124__Scallion_mosaic_virus__157018
Identity
- Accession:
- NP_734124 ↗
- Protein ID:
- HC-Pro_protein
- Kingdom:
- euk
Quality
84.4
mean pLDDT
Taxonomy
Orthornavirae›
Pisuviricota›
Stelpaviricetes›
Patatavirales›
Potyviridae›
Potyvirus›
Scallion_mosaic_virus
TaxID: 157018
Cluster
View cluster (80 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
medium
residues 33-105
Domain cluster:
rep: HC-Pro__YP_009252411__Tobacco_mosqueado_virus__1792583__D31-64_66-104
CATH (44)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3qwwA03 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.72 | 52.0 | 3.78e-01 | 75.3% | 46.6% |
| 2yfaA02 | 1.20.1440.210 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › | 0.71 | 63.0 | 5.35e-01 | 100.0% | 61.2% |
| 3oxfA05 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.70 | 50.0 | 5.04e-01 | 97.3% | 73.3% |
| 2pqrA01 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.69 | 48.0 | 4.46e-01 | 94.5% | 57.0% |
| 2d9dA00 | 1.20.58.120 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain | 0.68 | 61.0 | 5.68e-01 | 98.6% | 80.9% |
| 2cz2A02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.68 | 61.0 | 5.07e-01 | 100.0% | 63.5% |
| 4kb2A01 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.66 | 58.0 | 5.12e-01 | 98.6% | 89.0% |
| 6vudA01 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.65 | 59.0 | 5.14e-01 | 100.0% | 88.1% |
| 3n2oA03 | 1.20.58.930 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.64 | 51.0 | 4.64e-01 | 95.9% | 65.6% |
| 2uubT00 | 1.20.58.110 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Ribosomal protein S20 | 0.64 | 50.0 | 4.63e-01 | 100.0% | 65.7% |
| 6fndA01 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.64 | 51.0 | 3.82e-01 | 97.3% | 34.4% |
| 2odmA00 | 1.10.287.750 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › SO2669-like | 0.63 | 53.0 | 5.26e-01 | 100.0% | 88.6% |
| 1yz5B00 | 1.20.190.20 | Mainly Alpha › Up-down Bundle › Delta-Endotoxin; domain 1 › 14-3-3 domain | 0.63 | 55.0 | 3.79e-01 | 94.5% | 39.3% |
| 2nn4A00 | 1.10.287.760 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › YqgQ-like | 0.63 | 42.0 | 4.47e-01 | 87.7% | 80.6% |
| 5wp3B00 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.63 | 54.0 | 4.87e-01 | 97.3% | 82.4% |
| 1nigA00 | 1.20.1200.10 | Mainly Alpha › Up-down Bundle › Hypothetical Protein Ta1238; Chain: A; › Cobalamin adenosyltransferase-like | 0.62 | 56.0 | 4.45e-01 | 100.0% | 89.7% |
| 5tqbB01 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.62 | 55.0 | 3.54e-01 | 98.6% | 30.7% |
| 3fbzA01 | 1.20.58.800 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.61 | 48.0 | 4.38e-01 | 100.0% | 61.8% |
| 2qywA00 | 1.20.58.400 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › t-snare proteins | 0.61 | 54.0 | 4.97e-01 | 98.6% | 90.5% |
| 3lsjA02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.61 | 52.0 | 4.11e-01 | 95.9% | 51.6% |
| 3hmfA00 | 1.20.920.10 | Mainly Alpha › Up-down Bundle › Histone Acetyltransferase; Chain A › Bromodomain-like | 0.61 | 52.0 | 4.44e-01 | 94.5% | 67.2% |
| 4cqiA00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.60 | 54.0 | 4.74e-01 | 100.0% | 94.4% |
| 4gnkE00 | 1.20.1230.10 | Mainly Alpha › Up-down Bundle › Phospholipase C Beta; Chain: A › Phospholipase C beta, distal C-terminal domain | 0.60 | 53.0 | 3.70e-01 | 100.0% | 80.9% |
| 1cunA01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.60 | 52.0 | 4.72e-01 | 100.0% | 90.2% |
| 3onjA00 | 1.20.58.400 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › t-snare proteins | 0.59 | 50.0 | 4.58e-01 | 94.5% | 82.5% |
| 5uiyA00 | 1.20.920.10 | Mainly Alpha › Up-down Bundle › Histone Acetyltransferase; Chain A › Bromodomain-like | 0.59 | 50.0 | 4.46e-01 | 94.5% | 73.8% |
| 1br0A00 | 1.20.58.70 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.59 | 52.0 | 4.43e-01 | 100.0% | 86.7% |
| 1u5pA01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.59 | 52.0 | 4.56e-01 | 98.6% | 82.4% |
| 3bhqA00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.58 | 50.0 | 3.73e-01 | 100.0% | 55.4% |
| 4nuuB02 | 1.20.58.830 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.58 | 49.0 | 4.27e-01 | 100.0% | 91.1% |
| 1ugoA00 | 1.20.58.120 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain | 0.58 | 51.0 | 4.63e-01 | 100.0% | 75.8% |
| 6lumG01 | 1.20.1300.10 | Mainly Alpha › Up-down Bundle › 3 helical TM bundles of succinate and fumarate reductases › Fumarate reductase/succinate dehydrogenase, transmembrane subunit | 0.57 | 45.0 | 3.89e-01 | 83.6% | 80.4% |
| 3ehmA03 | 1.20.120.840 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › SusD-like, tetratrico peptide repeats domain | 0.57 | 50.0 | 4.24e-01 | 95.9% | 100.0% |
| 3pe0A02 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.56 | 48.0 | 4.33e-01 | 100.0% | 83.0% |
| 4bpxD00 | 1.20.930.80 | Mainly Alpha › Up-down Bundle › Transcription Elongation Factor S-II; Chain A › | 0.56 | 45.0 | 3.32e-01 | 91.8% | 82.6% |
| 4xxiA00 | 1.10.490.20 | Mainly Alpha › Orthogonal Bundle › Globin-like › Phycocyanins | 0.56 | 49.0 | 3.92e-01 | 100.0% | 57.1% |
| 2ycdA02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.56 | 48.0 | 4.15e-01 | 97.3% | 67.5% |
| 4hehA01 | 1.10.1240.10 | Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › Methionine synthase domain | 0.55 | 44.0 | 4.25e-01 | 87.7% | 80.7% |
| 5ko4A00 | 1.20.920.10 | Mainly Alpha › Up-down Bundle › Histone Acetyltransferase; Chain A › Bromodomain-like | 0.55 | 43.0 | 4.01e-01 | 90.4% | 76.2% |
| 3wd6A02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.54 | 46.0 | 4.03e-01 | 100.0% | 69.5% |
| 5mmjo00 | 1.10.287.10 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › S15/NS1, RNA-binding | 0.54 | 44.0 | 4.44e-01 | 93.2% | 93.3% |
| 3ll9B00 | 3.40.1160.10 | Alpha Beta › 3-Layer(aba) Sandwich › Carbamate kinase › Acetylglutamate kinase-like | 0.53 | 47.0 | 3.28e-01 | 100.0% | 56.6% |
| 2qwoB00 | 1.10.287.110 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › DnaJ domain | 0.53 | 44.0 | 4.18e-01 | 100.0% | 97.8% |
| 5n17A01 | 1.20.920.10 | Mainly Alpha › Up-down Bundle › Histone Acetyltransferase; Chain A › Bromodomain-like | 0.52 | 41.0 | 3.80e-01 | 91.8% | 76.9% |
ECOD (37)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3574981 | 604.12.1.91 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › RSLD_CPSF6 | 0.80 | 65.0 | 6.68e-01 | 97.3% | 88.6% |
| 3924801 | 109.4.1.1643 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › RSLD_CPSF6 | 0.77 | 64.0 | 5.85e-01 | 100.0% | 68.4% |
| 3522050 | 109.3.1.131 ↗ | alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › INT_SG_DDX_CT_C | 0.77 | 53.0 | 5.29e-01 | 100.0% | 70.3% |
| 3605710 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.70 | 61.0 | 6.05e-01 | 97.3% | 90.7% |
| 3707101 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.69 | 51.0 | 3.54e-01 | 93.2% | 23.2% |
| 3199299 | 109.4.1.1391 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Sec10_HB, Sec10_N | 0.69 | 60.0 | 3.46e-01 | 100.0% | 20.0% |
| 3277087 | 192.4.1.0 ↗ | alpha bundles › Long alpha-hairpin › Ribosomal protein L29 (L29p) › Ribosomal protein L29 (L29p) | 0.69 | 55.0 | 5.02e-01 | 98.6% | 65.3% |
| 3239387 | 2485.1.1.0 ↗ | a+b three layers › Thioredoxin-like › Thioredoxin-like › Thioredoxin-like | 0.67 | 60.0 | 4.27e-01 | 100.0% | 40.0% |
| 3363017 | 601.1.1.51 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › IPGAL1_C | 0.67 | 53.0 | 4.23e-01 | 100.0% | 43.0% |
| 3530379 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.66 | 58.0 | 4.88e-01 | 93.2% | 84.3% |
| 3684136 | 604.1.1.154 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › PF27021 | 0.66 | 59.0 | 5.11e-01 | 98.6% | 90.9% |
| 3682587 | 109.4.1.1731 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › HAT_Syf1_CNRKL1_C, HAT_Syf1_CNRKL1_N | 0.65 | 58.0 | 3.68e-01 | 98.6% | 22.3% |
| 3503488 | 109.4.1.1352 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › EFR3_ARM, EFR3 | 0.65 | 46.0 | 3.04e-01 | 76.7% | 40.9% |
| 4843090 | 310.2.1.0 ↗ | a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF | 0.64 | 56.0 | 4.90e-01 | 98.6% | 92.0% |
| 4017858 | 109.4.1.1391 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Sec10_HB, Sec10_N | 0.64 | 55.0 | 3.59e-01 | 93.2% | 28.0% |
| 3396401 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.63 | 56.0 | 4.85e-01 | 100.0% | 84.3% |
| 3389546 | 604.1.1.1 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin | 0.63 | 53.0 | 5.17e-01 | 94.5% | 85.0% |
| 3918080 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.63 | 56.0 | 5.04e-01 | 100.0% | 87.0% |
| 4015729 | 192.7.1.0 ↗ | alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm | 0.62 | 46.0 | 3.91e-01 | 79.5% | 55.2% |
| 3973406 | 371.1.1.0 ↗ | few secondary structure elements › Phospholipase A2, PLA2 › Phospholipase A2, PLA2 › Phospholipase A2, PLA2 | 0.62 | 53.0 | 4.90e-01 | 100.0% | 82.0% |
| 3497641 | 604.1.1.1 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin | 0.62 | 52.0 | 4.71e-01 | 93.2% | 88.0% |
| 3880178 | 192.8.1.92 ↗ | alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain › CUPID | 0.61 | 53.0 | 5.18e-01 | 98.6% | 95.0% |
| 3766956 | 622.4.1.22 ↗ | alpha bundles › YvfG-like › Mite allergen Der p 5-related › Mite allergen Der p 5-related › FAM186A-B_N | 0.60 | 52.0 | 4.37e-01 | 97.3% | 57.5% |
| 3489767 | 604.1.1.1 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin | 0.60 | 52.0 | 4.43e-01 | 100.0% | 72.8% |
| 3620806 | 604.1.1.1 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin | 0.59 | 52.0 | 4.01e-01 | 100.0% | 54.7% |
| 4999825 | 4995.1.1.1 ↗ | alpha arrays › Methionine synthase domain-like › Methionine synthase domain-like › Methionine synthase domain-like › B12-binding_2 | 0.59 | 46.0 | 4.16e-01 | 89.0% | 62.0% |
| 3755130 | 604.1.1.1 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin | 0.59 | 52.0 | 4.61e-01 | 98.6% | 86.7% |
| 3920202 | 601.16.1.15 ↗ | alpha bundles › Four-helical up-and-down bundle › FAT domain of focal adhesion kinase › FAT domain of focal adhesion kinase › CRIC_ras_sig | 0.58 | 49.0 | 4.10e-01 | 100.0% | 60.7% |
| 3272287 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.58 | 50.0 | 4.58e-01 | 100.0% | 87.0% |
| 3756566 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.58 | 50.0 | 3.24e-01 | 100.0% | 25.3% |
| 3757581 | 604.1.1.1 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin | 0.58 | 51.0 | 4.54e-01 | 100.0% | 87.6% |
| 3876659 | 220.1.1.0 ↗ | beta barrels › PH domain-like › PH domain-like › PH domain-like | 0.57 | 49.0 | 3.44e-01 | 98.6% | 36.4% |
| 3885709 | 192.13.1.0 ↗ | alpha bundles › Long alpha-hairpin › ISY1 N-terminal domain-like › ISY1 N-terminal domain-like | 0.56 | 43.0 | 4.35e-01 | 83.6% | 86.7% |
| 1392345 | 4995.1.1.2 ↗ | alpha arrays › Methionine synthase domain-like › Methionine synthase domain-like › Methionine synthase domain-like › AppA_4HB | 0.55 | 43.0 | 3.95e-01 | 87.7% | 67.0% |
| 3521280 | 604.1.1.256 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Wbp11 | 0.55 | 47.0 | 3.89e-01 | 97.3% | 57.0% |
| 3737296 | 192.2.1.18 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › ING | 0.54 | 42.0 | 3.49e-01 | 83.6% | 88.5% |
| 3965294 | 3558.1.1.0 ↗ | alpha arrays › HSDR subunit helical domain › HSDR subunit helical domain › HSDR subunit helical domain | 0.53 | 43.0 | 3.96e-01 | 89.0% | 75.8% |
D2
medium
residues 112-169
Domain cluster:
rep: HC-Pro_protein__YP_006405405__Basella_rugose_mosaic_virus__373398__D110-165
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00851.25 best | Peptidase_C6 | 26.9 | 3.40e-06 | 100.0% | 13.0% |
D3
medium
residues 272-306_322-379_404-457
Domain cluster:
rep: HC-Pro_protein__YP_006590094__Chinese_yam_necrotic_mosaic_virus__128818__D95-261
Pfam (2)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00851.25 best | Peptidase_C6 | 79.3 | 4.30e-22 | 64.6% | 23.9% |
| PF00851.25 | Peptidase_C6 | 71.9 | 7.50e-20 | 37.4% | 12.3% |