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HC-Pro_protein

Euk-Vir

Narcissus_yellow_stripe_virus

HC-Pro_protein__YP_002308556__Narcissus_yellow_stripe_virus__160843

Identity

Accession:
YP_002308556 ↗
Protein ID:
HC-Pro_protein
Kingdom:
euk

Quality

83.9 mean pLDDT

Taxonomy

Orthornavirae› Pisuviricota› Stelpaviricetes› Patatavirales› Potyviridae› Potyvirus› Narcissus_yellow_stripe_virus

TaxID: 160843

Cluster

View cluster (80 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 32-106
PDB
Domain cluster: rep: HC-Pro__YP_009252411__Tobacco_mosqueado_virus__1792583__D31-64_66-104
CATH (40)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2yjkC00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.71 65.0 5.02e-01 100.0% 86.0%
5o5jT00 1.20.58.110 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Ribosomal protein S20 0.70 57.0 5.48e-01 100.0% 77.6%
4dmvA01 1.20.58.1190 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.69 54.0 5.25e-01 100.0% 76.5%
3uj9A00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.69 61.0 4.20e-01 98.7% 89.5%
2yfaA02 1.20.1440.210 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 0.67 58.0 5.02e-01 100.0% 62.9%
2uubT00 1.20.58.110 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Ribosomal protein S20 0.65 51.0 4.76e-01 100.0% 67.7%
4oydB00 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.64 57.0 4.95e-01 100.0% 91.5%
4wzxA01 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.64 54.0 5.50e-01 97.3% 92.0%
6fndA01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.64 51.0 3.83e-01 96.0% 34.9%
2nn4A00 1.10.287.760 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › YqgQ-like 0.63 41.0 4.42e-01 86.7% 80.6%
1dk8A02 1.10.167.10 Mainly Alpha › Orthogonal Bundle › Regulator of G-protein Signalling 4; domain 2 › Regulator of G-protein Signalling 4, domain 2 0.63 50.0 4.89e-01 100.0% 78.8%
3pe0A01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.62 56.0 5.07e-01 100.0% 92.1%
4kb2A01 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.62 54.0 4.84e-01 100.0% 89.0%
3bhqA00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.62 51.0 3.80e-01 93.3% 39.1%
3iu5A00 1.20.920.10 Mainly Alpha › Up-down Bundle › Histone Acetyltransferase; Chain A › Bromodomain-like 0.62 52.0 4.54e-01 93.3% 69.3%
2odmA00 1.10.287.750 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › SO2669-like 0.61 52.0 5.18e-01 100.0% 92.4%
8ek4A01 1.20.120.20 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein 0.61 49.0 4.17e-01 92.0% 79.7%
1cunA01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.61 54.0 4.89e-01 100.0% 92.2%
3hmfA00 1.20.920.10 Mainly Alpha › Up-down Bundle › Histone Acetyltransferase; Chain A › Bromodomain-like 0.60 51.0 4.42e-01 93.3% 68.1%
4n4gA01 1.20.920.10 Mainly Alpha › Up-down Bundle › Histone Acetyltransferase; Chain A › Bromodomain-like 0.60 52.0 4.59e-01 96.0% 65.8%
1dd5A01 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.60 52.0 4.65e-01 100.0% 90.8%
1rq0A01 6.10.140.160 Special › Helix non-globular › Helix Hairpins › 0.60 40.0 3.87e-01 82.7% 61.4%
2aj4B03 1.20.1440.340 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 0.60 49.0 3.92e-01 93.3% 69.1%
1m62A00 1.20.58.120 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain 0.60 52.0 4.98e-01 100.0% 85.1%
1s35A02 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.60 53.0 4.67e-01 100.0% 85.5%
4flbA00 1.25.40.90 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.60 45.0 3.85e-01 97.3% 48.1%
4ap2B01 1.20.1310.10 Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats 0.59 51.0 4.28e-01 100.0% 60.4%
3pe0A02 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.59 51.0 4.62e-01 100.0% 87.7%
1ugoA00 1.20.58.120 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain 0.57 50.0 4.62e-01 100.0% 77.8%
2vgxB00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.57 50.0 4.03e-01 97.3% 57.9%
2ycdA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.56 49.0 4.25e-01 98.7% 70.9%
1siqA03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.56 47.0 3.80e-01 96.0% 65.8%
6wfqC01 1.20.120.530 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › GntR ligand-binding domain-like 0.55 41.0 3.34e-01 78.7% 61.3%
3t6gB00 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.55 47.0 4.00e-01 100.0% 64.9%
2odvA01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.55 48.0 4.25e-01 100.0% 89.3%
2yogA00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.55 46.0 3.48e-01 97.3% 69.5%
1np7A02 1.25.40.80 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.54 43.0 3.70e-01 93.3% 54.6%
2y39A00 1.20.120.1490 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.53 46.0 4.11e-01 100.0% 86.4%
4hehA01 1.10.1240.10 Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › Methionine synthase domain 0.53 41.0 4.06e-01 86.7% 83.1%
1vdyA00 1.25.40.90 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.50 44.0 3.62e-01 100.0% 85.7%
ECOD (25)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3522050 109.3.1.131 ↗ alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › INT_SG_DDX_CT_C 0.76 52.0 5.30e-01 97.3% 71.6%
5019542 622.4.1.67 ↗ alpha bundles › YvfG-like › Mite allergen Der p 5-related › Mite allergen Der p 5-related › DUF5518 0.69 48.0 4.43e-01 73.3% 79.8%
3277087 192.4.1.0 ↗ alpha bundles › Long alpha-hairpin › Ribosomal protein L29 (L29p) › Ribosomal protein L29 (L29p) 0.68 54.0 4.95e-01 97.3% 66.3%
3782809 603.1.1.17 ↗ alpha bundles › STAT-like › t-snare proteins › t-snare proteins › SNARE 0.67 61.0 4.56e-01 100.0% 66.7%
3703063 604.3.1.0 ↗ alpha bundles › Spectrin repeat-like › BAG domain › BAG domain 0.67 59.0 5.48e-01 100.0% 94.7%
3640330 604.1.1.0 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.66 58.0 4.80e-01 100.0% 66.4%
3630494 611.3.1.1 ↗ alpha bundles › N-cbl like › Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 › Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 › Med26 0.66 47.0 4.48e-01 93.3% 63.3%
4393454 632.15.1.6 ↗ alpha bundles › immunoglobulin/albumin-binding domain-like › Staphylococcal complement inhibitor (SCIN) › Staphylococcal complement inhibitor (SCIN) › DUF2678 0.64 42.0 3.81e-01 81.3% 50.0%
3547209 192.15.1.204 ↗ alpha bundles › Long alpha-hairpin › Endosomal sorting complex assembly domains › Endosomal sorting complex assembly domains › DUF2678 0.64 42.0 3.81e-01 81.3% 50.0%
4027582 603.1.1.120 ↗ alpha bundles › STAT-like › t-snare proteins › t-snare proteins › DUF846 0.62 55.0 4.75e-01 100.0% 85.0%
3879381 603.2.1.1 ↗ alpha bundles › STAT-like › STAT › STAT › STAT_alpha 0.61 55.0 4.33e-01 100.0% 68.4%
3197870 604.1.1.0 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.61 54.0 4.51e-01 100.0% 77.0%
3277234 604.12.1.0 ↗ alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.61 53.0 4.06e-01 100.0% 89.4%
3442391 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.60 43.0 3.63e-01 77.3% 43.0%
3171100 603.1.1.100 ↗ alpha bundles › STAT-like › t-snare proteins › t-snare proteins › PF27017 0.60 53.0 4.84e-01 100.0% 91.0%
3472574 4967.1.1.0 ↗ alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases 0.60 55.0 4.21e-01 100.0% 91.9%
1693420 604.31.1.1 ↗ alpha bundles › Spectrin repeat-like › F-actin-bundling protein ABP34 C-terminal domain › F-actin-bundling protein ABP34 C-terminal domain › F_actin_bund_C 0.60 51.0 4.62e-01 98.7% 98.1%
3606103 604.12.1.0 ↗ alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.59 51.0 3.85e-01 100.0% 66.0%
3588019 633.31.1.0 ↗ alpha bundles › Bromodomain-like › Four-helical bundle insertion domain in pyruvate-ferredoxin oxidoreductase › Four-helical bundle insertion domain in pyruvate-ferredoxin oxidoreductase 0.59 41.0 4.22e-01 97.3% 80.0%
1019380 604.5.1.2 ↗ alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU 0.58 50.0 4.53e-01 100.0% 87.0%
3390957 5069.1.3.4 ↗ alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits › CybS 0.54 39.0 3.54e-01 78.7% 63.6%
3742380 109.4.1.329 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › CDC14 0.54 47.0 3.37e-01 100.0% 35.3%
3838954 604.12.1.0 ↗ alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.53 46.0 4.12e-01 100.0% 85.5%
4485359 103.2.1.0 ↗ alpha arrays › RuvA-C › ATP cone › ATP cone 0.53 37.0 3.53e-01 98.7% 61.1%
3295564 109.4.1.21 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › ENTH 0.52 46.0 3.68e-01 100.0% 80.0%
D2 medium residues 110-173
PDB
Domain cluster: rep: HC-Pro_protein__YP_006405405__Basella_rugose_mosaic_virus__373398__D110-165
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00851.25 best Peptidase_C6 38.6 9.50e-10 100.0% 14.1%
D3 medium residues 209-229_291-458
PDB
Domain cluster: rep: HC-Pro_protein__YP_006590094__Chinese_yam_necrotic_mosaic_virus__128818__D95-261
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00851.25 best Peptidase_C6 223.2 8.90e-66 88.9% 38.2%