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HC-Pro_protein
Euk-VirPassion_fruit_woodiness_virus
HC-Pro_protein__YP_004063673__Passion_fruit_woodiness_virus__31732
Identity
- Accession:
- YP_004063673 ↗
- Protein ID:
- HC-Pro_protein
- Kingdom:
- euk
Quality
83.5
mean pLDDT
Taxonomy
Orthornavirae›
Pisuviricota›
Stelpaviricetes›
Patatavirales›
Potyviridae›
Potyvirus›
Passion_fruit_woodiness_virus
TaxID: 31732
Cluster
View cluster (80 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 25-106
Domain cluster:
rep: HC-Pro__YP_009252411__Tobacco_mosqueado_virus__1792583__D31-64_66-104
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00851.25 best | Peptidase_C6 | 26.3 | 5.10e-06 | 100.0% | 12.7% |
D2
high
residues 114-167
Domain cluster:
rep: HC-Pro_protein__YP_006405405__Basella_rugose_mosaic_virus__373398__D110-165
CATH (29)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2kw6A00 | 6.10.140.1300 | Special › Helix non-globular › Helix Hairpins › | 0.74 | 60.0 | 5.64e-01 | 88.9% | 83.1% |
| 4nb5B02 | 1.10.287.160 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat | 0.74 | 53.0 | 5.04e-01 | 75.9% | 75.0% |
| 2p7vA00 | 1.20.120.1370 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Regulator of RNA polymerase sigma(70) subunit, domain 4 | 0.73 | 60.0 | 4.36e-01 | 92.6% | 41.7% |
| 1ia6A00 | 1.50.10.10 | Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase › | 0.71 | 63.0 | 3.71e-01 | 100.0% | 65.5% |
| 1vt0k00 | 1.10.3230.20 | Mainly Alpha › Orthogonal Bundle › Hypothetical protein yqbg › P22 tail accessory factor (Gp4) | 0.71 | 61.0 | 4.53e-01 | 100.0% | 59.3% |
| 3vprA02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.70 | 49.0 | 3.58e-01 | 74.1% | 44.8% |
| 2wj9B00 | 3.30.70.3580 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Antirestriction protein | 0.69 | 54.0 | 4.09e-01 | 90.7% | 62.8% |
| 3qxfA00 | 1.50.10.10 | Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase › | 0.67 | 52.0 | 3.23e-01 | 85.2% | 30.0% |
| 4c1sA00 | 1.50.10.20 | Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase › | 0.66 | 57.0 | 3.46e-01 | 100.0% | 59.2% |
| 1dvpA01 | 1.25.40.90 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.65 | 47.0 | 3.55e-01 | 77.8% | 57.9% |
| 2lhrA00 | 1.20.58.1270 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.64 | 49.0 | 4.40e-01 | 85.2% | 60.3% |
| 3favD00 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.63 | 46.0 | 4.01e-01 | 75.9% | 53.8% |
| 1w9rA00 | 1.20.58.440 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › choline binding protein A | 0.63 | 53.0 | 4.26e-01 | 100.0% | 69.7% |
| 2pbiA02 | 1.10.1240.60 | Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › | 0.63 | 43.0 | 3.61e-01 | 75.9% | 38.6% |
| 4nqiD00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.63 | 54.0 | 3.58e-01 | 100.0% | 72.4% |
| 4gzrC00 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.63 | 45.0 | 4.37e-01 | 75.9% | 72.1% |
| 2ijrA02 | 1.10.3530.10 | Mainly Alpha › Orthogonal Bundle › Api92-like › Api92-like | 0.62 | 52.0 | 3.76e-01 | 100.0% | 33.5% |
| 4fx0A00 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.61 | 47.0 | 3.69e-01 | 87.0% | 68.9% |
| 3vldA02 | 1.25.40.580 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.61 | 47.0 | 3.42e-01 | 85.2% | 46.4% |
| 1nklA00 | 1.10.225.10 | Mainly Alpha › Orthogonal Bundle › NK-Lysin › Saposin-like | 0.60 | 41.0 | 3.64e-01 | 72.2% | 47.4% |
| 3d8lA00 | 1.10.8.940 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Uncharacterised protein, phage p2 ORF12 | 0.58 | 40.0 | 3.51e-01 | 75.9% | 48.4% |
| 6fhpD00 | 1.10.390.10 | Mainly Alpha › Orthogonal Bundle › Neutral Protease; domain 2 › Neutral Protease Domain 2 | 0.58 | 43.0 | 4.14e-01 | 81.5% | 71.0% |
| 1vibA00 | 1.10.287.120 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Neurotoxin B-IV-like | 0.57 | 39.0 | 3.96e-01 | 72.2% | 78.2% |
| 1qqfA00 | 1.50.10.20 | Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase › | 0.57 | 46.0 | 3.02e-01 | 96.3% | 56.9% |
| 3jsbA01 | 1.20.1440.300 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › RNA-directed RNA polymerase L, helical domain | 0.57 | 42.0 | 3.88e-01 | 88.9% | 69.1% |
| 2qtlA03 | 3.40.50.80 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module | 0.55 | 50.0 | 3.55e-01 | 100.0% | 60.0% |
| 7zm7601 | 1.20.120.1200 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › NADH-ubiquinone/plastoquinone oxidoreductase chain 6, subunit NuoJ | 0.54 | 43.0 | 3.27e-01 | 100.0% | 37.7% |
| 1aisB01 | 1.10.472.10 | Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like | 0.54 | 43.0 | 3.61e-01 | 90.7% | 54.5% |
| 2ba0A03 | 3.30.1370.10 | Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › K Homology domain, type 1 | 0.53 | 45.0 | 3.86e-01 | 92.6% | 86.7% |
ECOD (10)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3998272 | 7.1.1.1 ↗ | beta barrels › PDZ domain › PDZ domain › PDZ domain › PDZ | 0.85 | 57.0 | 4.88e-01 | 70.4% | 44.7% |
| 4169956 | 604.12.1.26 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › HemX | 0.71 | 53.0 | 4.72e-01 | 79.6% | 72.0% |
| 3206233 | 109.4.1.1739 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Cohesin_HEAT, Nipped-B_C, PDS5 | 0.71 | 57.0 | 3.04e-01 | 88.9% | 6.0% |
| 3876892 | 375.2.1.0 ↗ | few secondary structure elements › Rubredoxin-like › YfgJ-like › YfgJ-like | 0.67 | 47.0 | 4.19e-01 | 83.3% | 51.2% |
| 3404678 | 109.3.1.147 ↗ | alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › DUF4485 | 0.66 | 41.0 | 3.47e-01 | 72.2% | 38.9% |
| 1503553 | 3796.1.1.1 ↗ | alpha arrays › Iron-regulated surface determinant protein H linker domain › Iron-regulated surface determinant protein H linker domain › Iron-regulated surface determinant protein H linker domain › Isd_H_B_linker | 0.64 | 49.0 | 4.40e-01 | 85.2% | 60.3% |
| 3594688 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.60 | 51.0 | 3.39e-01 | 96.3% | 31.9% |
| 3843340 | 6092.1.1.1 ↗ | alpha bundles › Helical extension domain in Regulator of G-protein signaling 9 › Helical extension domain in Regulator of G-protein signaling 9 › Helical extension domain in Regulator of G-protein signaling 9 › RGS_DHEX | 0.60 | 43.0 | 3.63e-01 | 79.6% | 42.0% |
| 3435259 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.60 | 50.0 | 3.95e-01 | 100.0% | 52.8% |
| 3372218 | 109.27.1.3 ↗ | alpha superhelices › Repetitive alpha hairpins › BACK domain › BACK domain › NPH3 | 0.53 | 40.0 | 3.73e-01 | 85.2% | 94.3% |
D3
medium
residues 174-268_318-338
Domain cluster:
rep: HC-Pro__YP_001936179__Verbena_virus_Y__515446__D186-209_223-267_313-337
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00851.25 best | Peptidase_C6 | 55.2 | 8.60e-15 | 81.9% | 17.3% |
D4
medium
residues 269-317_339-457
Domain cluster:
rep: HC-Pro_protein__YP_006590094__Chinese_yam_necrotic_mosaic_virus__128818__D95-261
Pfam (2)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00851.25 best | Peptidase_C6 | 187.5 | 6.10e-55 | 72.6% | 27.3% |
| PF00851.25 | Peptidase_C6 | 33.1 | 4.20e-08 | 30.4% | 10.2% |