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HC-Pro_protein

Euk-Vir

Basella_rugose_mosaic_virus

HC-Pro_protein__YP_006405405__Basella_rugose_mosaic_virus__373398

Identity

Accession:
YP_006405405 ↗
Protein ID:
HC-Pro_protein
Kingdom:
euk

Quality

82.7 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 21-101
PDB
CATH (16)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1vp7A00 1.10.287.1040 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Exonuclease VII, small subunit 0.65 33.0 3.56e-01 77.8% 55.9%
2l9mA00 1.10.533.10 Mainly Alpha › Orthogonal Bundle › Death Domain, Fas › Death Domain, Fas 0.59 37.0 3.18e-01 75.3% 38.6%
2lefA00 1.10.30.10 Mainly Alpha › Orthogonal Bundle › DNA Binding (I), subunit A › High mobility group box domain 0.59 42.0 4.13e-01 75.3% 82.6%
4s3mB02 1.10.1040.10 Mainly Alpha › Orthogonal Bundle › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 0.58 43.0 4.03e-01 88.9% 62.3%
6xm1A02 3.90.830.10 Alpha Beta › Alpha-Beta Complex › Syntaxin Binding Protein 1; Chain A, domain 2 › Sec1/Munc18 (SM) protein, domain 3a 0.58 38.0 3.43e-01 77.8% 47.8%
3nivC02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.57 47.0 4.14e-01 92.6% 74.2%
1ungE00 1.10.472.10 Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like 0.57 40.0 3.33e-01 74.1% 55.8%
3d36B02 1.10.287.130 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Signal transduction histidine kinase, dimerisation/phosphotransfer (DHp) domain 0.56 37.0 4.05e-01 76.5% 90.2%
4h63H01 1.20.58.1710 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.56 39.0 4.06e-01 81.5% 83.3%
3fghA00 1.10.30.10 Mainly Alpha › Orthogonal Bundle › DNA Binding (I), subunit A › High mobility group box domain 0.56 38.0 4.08e-01 71.6% 97.0%
4abmD00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.54 39.0 4.03e-01 80.2% 80.5%
3okqA00 1.20.58.1540 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Actin interacting protein 3, C-terminal domain 0.54 38.0 3.36e-01 75.3% 69.6%
3fiwA02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.53 38.0 3.48e-01 85.2% 53.8%
4hr1A00 1.20.1270.410 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.53 44.0 3.94e-01 95.1% 80.5%
3q9oA02 3.90.1350.10 Alpha Beta › Alpha-Beta Complex › Exotoxin A, middle domain › Exotoxin A, middle domain 0.52 39.0 3.19e-01 82.7% 73.7%
1zpyA00 6.10.140.1960 Special › Helix non-globular › Helix Hairpins › 0.51 41.0 3.97e-01 90.1% 82.4%
ECOD (13)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3522050 109.3.1.131 alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › INT_SG_DDX_CT_C 0.65 41.0 4.33e-01 86.4% 71.6%
4456090 5086.1.1.94 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HB_LcnD 0.60 40.0 3.00e-01 80.2% 24.9%
4355181 632.13.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like 0.59 36.0 3.92e-01 72.8% 73.8%
3975479 109.1.1.6 alpha superhelices › Repetitive alpha hairpins › Glutathione S-transferase (GST)-C › Glutathione S-transferase (GST)-C › GST_C_2 0.59 49.0 4.22e-01 92.6% 72.3%
3519620 190.1.1.0 alpha arrays › HMG-box-like › HMG-box › HMG-box 0.57 44.0 4.07e-01 85.2% 91.8%
3510680 192.15.1.0 alpha bundles › Long alpha-hairpin › Endosomal sorting complex assembly domains › Endosomal sorting complex assembly domains 0.57 40.0 4.23e-01 74.1% 97.1%
4026047 310.2.1.0 a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF 0.56 43.0 4.32e-01 86.4% 94.1%
3689730 190.1.1.3 alpha arrays › HMG-box-like › HMG-box › HMG-box › HMG_box_2 0.55 41.0 4.14e-01 85.2% 97.6%
3701064 3567.1.1.0 a+b duplicates or obligate multimers › MPER trimer › MPER trimer › MPER trimer 0.54 40.0 3.23e-01 77.8% 40.0%
3435024 109.4.1.1262 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, PPR_1, PPR_2, PPR_long 0.54 41.0 2.62e-01 100.0% 14.8%
3533358 190.1.1.1 alpha arrays › HMG-box-like › HMG-box › HMG-box › HMG_box 0.52 39.0 3.73e-01 81.5% 87.4%
3749294 605.1.1.177 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › PF27917 0.51 39.0 3.73e-01 81.5% 72.6%
2035519 604.1.1.1 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin 0.51 39.0 3.55e-01 86.4% 69.7%
D2 high residues 110-165
PDB
Domain cluster: representative
CATH (35)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3f2bA08 1.10.150.870 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › 0.86 59.0 4.35e-01 71.4% 29.2%
3r84A00 1.10.287.3490 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.83 58.0 5.11e-01 73.2% 67.9%
1urfA00 1.10.287.160 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat 0.82 57.0 5.01e-01 73.2% 63.0%
2mtqA00 1.20.58.130 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.81 56.0 5.11e-01 73.2% 56.2%
2kw6A00 6.10.140.1300 Special › Helix non-globular › Helix Hairpins › 0.79 63.0 5.94e-01 83.9% 81.5%
4nb5B02 1.10.287.160 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat 0.78 54.0 5.22e-01 73.2% 96.9%
1jalA03 1.10.150.300 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Obg-related GTPase Ych/YyaF, coiled-coil domain 0.77 54.0 4.73e-01 73.2% 50.6%
2b5uA02 1.10.287.620 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix Hairpins 0.77 52.0 3.74e-01 71.4% 49.1%
8carA01 1.50.10.10 Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase › 0.76 61.0 3.64e-01 85.7% 39.1%
2y39A00 1.20.120.1490 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.76 53.0 4.23e-01 73.2% 46.4%
1wp7A00 1.10.287.770 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › YojJ-like 0.76 52.0 4.96e-01 71.4% 67.2%
6ll8A01 3.90.1640.10 Alpha Beta › Alpha-Beta Complex › inorganic pyrophosphatase (n-terminal core) › inorganic pyrophosphatase (n-terminal core) 0.74 61.0 4.18e-01 89.3% 69.9%
2afaA00 1.50.10.10 Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase › 0.73 51.0 3.03e-01 73.2% 10.8%
2yf4F00 1.10.3420.10 Mainly Alpha › Orthogonal Bundle › putative ntp pyrophosphohydrolase like fold › putative ntp pyrophosphohydrolase like domain 0.71 48.0 3.60e-01 71.4% 30.8%
5zigA00 1.50.10.10 Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase › 0.70 58.0 3.44e-01 91.1% 41.8%
4hkrA00 1.20.140.140 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Calcium release-activated calcium channel protein Orai 0.70 58.0 4.28e-01 100.0% 53.9%
2p7vA00 1.20.120.1370 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Regulator of RNA polymerase sigma(70) subunit, domain 4 0.69 58.0 4.36e-01 100.0% 46.4%
1vt0k00 1.10.3230.20 Mainly Alpha › Orthogonal Bundle › Hypothetical protein yqbg › P22 tail accessory factor (Gp4) 0.67 56.0 4.26e-01 98.2% 57.9%
1zvzA02 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.67 56.0 4.46e-01 100.0% 71.0%
1wpaA01 6.10.140.340 Special › Helix non-globular › Helix Hairpins › 0.66 46.0 3.86e-01 73.2% 43.4%
4fgoA00 3.10.620.30 Alpha Beta › Roll › C8orf32 fold › 0.65 54.0 3.81e-01 94.6% 42.5%
1aa7A02 1.10.10.180 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Influenza matrix protein M1, N-terminal subdomain 2 0.65 54.0 4.93e-01 94.6% 97.4%
4gzrC00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.63 45.0 4.40e-01 75.0% 72.1%
2lhrA00 1.20.58.1270 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.63 43.0 3.96e-01 73.2% 53.8%
4kx7A04 1.25.50.20 Mainly Alpha › Alpha Horseshoe › Zincin-like fold › 0.62 43.0 2.74e-01 75.0% 23.2%
1sqmA04 1.25.40.320 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Peptidase M1, leukotriene A4 hydrolase/aminopeptidase C-terminal domain 0.62 40.0 2.98e-01 73.2% 24.8%
3favD00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.62 43.0 3.84e-01 73.2% 52.6%
8h1kA01 1.50.10.10 Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase › 0.61 53.0 3.16e-01 98.2% 38.2%
1gcvB00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.58 50.0 3.77e-01 96.4% 82.4%
4d6wB02 6.10.140.740 Special › Helix non-globular › Helix Hairpins › 0.56 47.0 4.08e-01 100.0% 90.2%
2b6cA01 1.20.1660.10 Mainly Alpha › Up-down Bundle › ARM repeat fold › Hypothetical protein (EF3068) 0.54 41.0 3.42e-01 89.3% 61.2%
6fakA02 1.10.246.10 Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › 0.54 44.0 4.06e-01 100.0% 90.1%
3d8lA00 1.10.8.940 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Uncharacterised protein, phage p2 ORF12 0.54 43.0 3.71e-01 89.3% 71.4%
1vibA00 1.10.287.120 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Neurotoxin B-IV-like 0.53 36.0 3.64e-01 71.4% 80.0%
1dvpA01 1.25.40.90 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.52 41.0 3.11e-01 85.7% 56.4%
ECOD (21)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
2665702 3146.1.1.3 a+b complex topology › gH main domain › gH main domain › gH main domain › Phage_glycop_gL 0.90 66.0 5.03e-01 76.8% 71.3%
4259085 3755.4.1.66 alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › MCPsignal 0.79 55.0 3.44e-01 73.2% 23.8%
3712411 3939.1.1.0 alpha duplicates or obligate multimers › XRCC4 C-terminal oligomerization domain › XRCC4 C-terminal oligomerization domain › XRCC4 C-terminal oligomerization domain 0.79 55.0 3.51e-01 73.2% 16.8%
1879027 244.1.1.6 a+b two layers › FAD-linked reductases, C-terminal domain-like › FAD-linked reductases-C › FAD-linked reductases-C › Amino_oxidase 0.76 53.0 3.17e-01 73.2% 10.8%
5083776 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.75 51.0 4.32e-01 71.4% 46.3%
4042824 192.8.1.0 alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain 0.75 51.0 4.52e-01 71.4% 92.5%
4960282 601.14.1.1 alpha bundles › Four-helical up-and-down bundle › Hemerythrin › Hemerythrin › Hemerythrin 0.73 67.0 4.56e-01 100.0% 47.0%
3543713 4.1.1.0 beta barrels › SH3 › SH3 › SH3 0.73 49.0 4.27e-01 71.4% 47.8%
3831657 145.1.1.58 alpha arrays › F-box domain › F-box domain › F-box domain › Chloroplast_duf 0.72 49.0 3.58e-01 73.2% 25.8%
3774121 150.1.1.119 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › Clusterin 0.70 49.0 3.57e-01 75.0% 68.8%
4595410 192.8.1.0 alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain 0.69 48.0 4.62e-01 75.0% 63.1%
3218140 188.1.1.1 alpha arrays › Nuclear receptor ligand-binding domain › Nuclear receptor ligand-binding domain › Nuclear receptor ligand-binding domain › Hormone_recep 0.69 57.0 3.64e-01 92.9% 39.3%
3594688 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.63 44.0 2.90e-01 73.2% 33.2%
1503553 3796.1.1.1 alpha arrays › Iron-regulated surface determinant protein H linker domain › Iron-regulated surface determinant protein H linker domain › Iron-regulated surface determinant protein H linker domain › Isd_H_B_linker 0.63 43.0 3.96e-01 73.2% 53.8%
3316618 103.1.1.0 alpha arrays › RuvA-C › RuvA-C, UBA, CRAL/TRIO-N, HBS1 › UBA-like domain 0.63 46.0 4.34e-01 80.4% 95.7%
4013459 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.57 49.0 2.97e-01 100.0% 21.0%
3435259 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.55 45.0 3.62e-01 96.4% 67.2%
3228072 188.1.1.1 alpha arrays › Nuclear receptor ligand-binding domain › Nuclear receptor ligand-binding domain › Nuclear receptor ligand-binding domain › Hormone_recep 0.55 48.0 3.16e-01 100.0% 52.5%
3263693 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.55 42.0 2.88e-01 91.1% 34.5%
3809254 509.1.1.1 alpha bundles › PAH2 domain › PAH2 domain › PAH2 domain › PAH 0.53 42.0 4.09e-01 94.6% 80.0%
3404678 109.3.1.147 alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › DUF4485 0.50 43.0 3.71e-01 98.2% 71.1%
D3 medium residues 181-266_309-339
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00851.25 best Peptidase_C6 59.1 5.80e-16 72.7% 15.4%
D4 medium residues 267-308_340-456
PDB
Pfam (2)
AccessionNameScoreE-valueQ covHMM cov
PF00851.25 best Peptidase_C6 188.1 4.10e-55 76.7% 26.8%
PF00851.25 Peptidase_C6 28.7 9.60e-07 25.8% 7.3%