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HC-Pro_protein

Euk-Vir

Celery_mosaic_virus

HC-Pro_protein__YP_006423974__Celery_mosaic_virus__112436

Identity

Accession:: YP_006423974 ↗
Protein ID:: HC-Pro_protein
Kingdom:: euk

Quality

85.9 mean pLDDT

Taxonomy

Orthornavirae› Pisuviricota› Stelpaviricetes› Patatavirales› Potyviridae› Potyvirus› Celery_mosaic_virus

TaxID: 112436

Cluster

View cluster (80 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 267-457

PDB

Domain cluster: rep: HC-Pro_protein__YP_006590094__Chinese_yam_necrotic_mosaic_virus__128818__D95-261

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF00851.25 best	Peptidase_C6	259.8	7.00e-77	100.0%	43.0%

D2 medium residues 28-106

PDB

Domain cluster: rep: HC-Pro__YP_009252411__Tobacco_mosqueado_virus__1792583__D31-64_66-104

CATH (43)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3k6tB00	1.20.5.4010	Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces ›	0.80	41.0	5.13e-01	77.2%	81.6%
3u8vA00	1.20.120.660	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › IL-4 antagonist (De novo design) like domain	0.73	53.0	5.23e-01	96.2%	72.3%
2vxxA00	1.20.1260.10	Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle	0.72	65.0	5.02e-01	100.0%	82.6%
2gnoA03	1.20.272.10	Mainly Alpha › Up-down Bundle › Zinc Finger, Delta Prime; domain 3 ›	0.71	53.0	4.91e-01	79.7%	65.0%
2yjkC00	1.20.1260.10	Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle	0.71	64.0	5.06e-01	100.0%	91.7%
3n71A03	1.25.40.10	Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain	0.70	49.0	3.55e-01	89.9%	26.8%
2d2sA01	1.20.58.1210	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Exo84p, N-terminal helical domain	0.70	54.0	4.75e-01	100.0%	56.0%
3r2kA00	1.20.1260.10	Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle	0.69	61.0	4.87e-01	97.5%	82.5%
4dyqA01	1.10.10.60	Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like	0.67	51.0	4.67e-01	79.7%	78.6%
1gt0D00	1.10.30.10	Mainly Alpha › Orthogonal Bundle › DNA Binding (I), subunit A › High mobility group box domain	0.65	47.0	4.77e-01	75.9%	89.9%
2ikbC00	1.20.141.10	Mainly Alpha › Up-down Bundle › Chitosanase, subunit A; domain 1 › Chitosanase, subunit A, domain 1	0.63	53.0	4.36e-01	100.0%	88.2%
2clbA01	1.20.1260.10	Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle	0.62	54.0	4.39e-01	100.0%	95.6%
1nigA00	1.20.1200.10	Mainly Alpha › Up-down Bundle › Hypothetical Protein Ta1238; Chain: A; › Cobalamin adenosyltransferase-like	0.62	54.0	4.43e-01	97.5%	91.1%
1dd5A01	1.10.132.20	Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor	0.61	41.0	3.73e-01	75.9%	50.5%
3kyiA00	1.20.120.160	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain	0.61	47.0	4.03e-01	88.6%	51.6%
3onjA00	1.20.58.400	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › t-snare proteins	0.61	53.0	4.95e-01	96.2%	93.8%
2v6kA02	1.20.1050.10	Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 ›	0.60	54.0	4.60e-01	100.0%	73.8%
2cz2A02	1.20.1050.10	Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 ›	0.60	51.0	4.48e-01	98.7%	69.8%
3nivC02	1.20.1050.10	Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 ›	0.60	52.0	4.54e-01	100.0%	77.4%
4oydB00	1.10.132.20	Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor	0.59	51.0	4.52e-01	98.7%	93.2%
2juaA00	1.20.1480.30	Mainly Alpha › Up-down Bundle › hypothetical protein mp506/mpn330, domain 1 › Designed four-helix bundle protein	0.57	49.0	4.56e-01	98.7%	75.5%
8etcb01	1.20.120.1190	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) ›	0.57	48.0	3.99e-01	96.2%	71.2%
3n00A00	1.10.565.10	Mainly Alpha › Orthogonal Bundle › Retinoid X Receptor › Retinoid X Receptor	0.57	43.0	3.35e-01	93.7%	35.3%
4nuuB02	1.20.58.830	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 ›	0.57	50.0	4.34e-01	98.7%	92.7%
6x6nA01	1.20.120.260	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Virulence factor YopE uncharacterised domain	0.56	42.0	3.70e-01	79.7%	94.0%
2hydA01	1.20.1560.10	Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain	0.55	40.0	2.68e-01	77.2%	19.2%
4yzgA00	3.60.40.10	Alpha Beta › 4-Layer Sandwich › Phosphatase 2c; domain 1 › PPM-type phosphatase domain	0.55	48.0	3.31e-01	98.7%	70.7%
7xpzA01	1.20.1720.10	Mainly Alpha › Up-down Bundle › Multidrug resistance protein D › Multidrug resistance protein D	0.55	47.0	3.09e-01	100.0%	89.3%
4mduA02	1.10.220.10	Mainly Alpha › Orthogonal Bundle › Annexin V; domain 1 › Annexin	0.55	37.0	3.69e-01	73.4%	67.1%
3dpjF00	1.10.357.10	Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2	0.54	46.0	3.61e-01	98.7%	70.7%
2aj4B03	1.20.1440.340	Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) ›	0.54	47.0	3.82e-01	100.0%	79.0%
2uubT00	1.20.58.110	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Ribosomal protein S20	0.54	45.0	4.30e-01	98.7%	86.9%
6vudA01	1.10.132.20	Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor	0.54	45.0	4.11e-01	96.2%	90.8%
4xxiA00	1.10.490.20	Mainly Alpha › Orthogonal Bundle › Globin-like › Phycocyanins	0.53	46.0	3.85e-01	100.0%	78.2%
3m0fB02	1.20.1050.10	Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 ›	0.53	46.0	4.06e-01	100.0%	76.4%
1p72A00	3.40.50.300	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases	0.53	45.0	3.08e-01	100.0%	34.1%
3bjdA01	1.10.1240.20	Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › Lytic transglycosylase, superhelical linker domain	0.53	41.0	4.00e-01	96.2%	76.1%
3gyuA00	1.10.565.10	Mainly Alpha › Orthogonal Bundle › Retinoid X Receptor › Retinoid X Receptor	0.53	42.0	3.10e-01	91.1%	86.8%
3ztaA00	1.10.490.130	Mainly Alpha › Orthogonal Bundle › Globin-like ›	0.53	41.0	3.53e-01	88.6%	81.3%
3wd6A02	1.20.1050.10	Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 ›	0.53	46.0	4.07e-01	100.0%	71.2%
2ycdA02	1.20.1050.10	Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 ›	0.52	44.0	3.97e-01	97.5%	78.6%
7ccmB01	1.10.437.10	Mainly Alpha › Orthogonal Bundle › Apoptosis Regulator Bcl-x › Blc2-like	0.51	43.0	3.55e-01	92.4%	58.0%
4u72A01	1.20.58.480	Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 ›	0.50	43.0	3.18e-01	97.5%	89.2%

ECOD (46)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
3726818	109.4.1.0 ↗	alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat	0.74	55.0	4.35e-01	92.4%	39.4%
3997799	109.4.1.0 ↗	alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat	0.73	51.0	3.26e-01	73.4%	30.9%
3522050	109.3.1.131 ↗	alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › INT_SG_DDX_CT_C	0.70	47.0	4.83e-01	94.9%	73.0%
3936736	150.1.1.0 ↗	alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin	0.67	58.0	4.93e-01	100.0%	74.8%
3465231	192.15.1.189 ↗	alpha bundles › Long alpha-hairpin › Endosomal sorting complex assembly domains › Endosomal sorting complex assembly domains › Frigida	0.66	56.0	5.64e-01	93.7%	91.3%
3325696	109.4.1.1279 ↗	alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, PPR_1, PPR_2, PPR_long, TPR_24	0.65	47.0	2.71e-01	74.7%	13.1%
3949626	5069.1.1.15 ↗	alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › Cytochrom_C_asm	0.65	55.0	4.36e-01	92.4%	71.0%
3741603	603.1.1.5 ↗	alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Syntaxin-6_N	0.64	52.0	4.48e-01	88.6%	63.2%
3582455	3843.1.1.0 ↗	alpha complex topology › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K › NADH-quinone oxidoreductase subunit K	0.64	50.0	5.12e-01	92.4%	89.3%
3200625	109.4.1.158 ↗	alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › ERAP1_C	0.64	42.0	2.82e-01	93.7%	16.9%
5067817	101.1.2.0 ↗	alpha arrays › HTH › HTH › winged helix domain	0.63	46.0	4.11e-01	77.2%	90.0%
3642331	109.4.1.1370 ↗	alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › HEAT, XMAP215_CLASP_TOG	0.63	44.0	3.71e-01	92.4%	43.0%
4060154	4974.1.1.0 ↗	alpha bundles › CRISPR-Cas system first helical domain › CRISPR-Cas system first helical domain › CRISPR-Cas system RNase C2c2 first helical domain	0.63	50.0	3.87e-01	100.0%	37.4%
3427778	604.1.1.144 ↗	alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › PF26575	0.63	46.0	4.63e-01	77.2%	78.8%
3191246	109.1.1.1 ↗	alpha superhelices › Repetitive alpha hairpins › Glutathione S-transferase (GST)-C › Glutathione S-transferase (GST)-C › GST_C	0.62	55.0	4.59e-01	100.0%	72.9%
3690963	5054.1.1.16 ↗	alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › KCH	0.62	53.0	3.95e-01	96.2%	83.9%
3240658	109.4.1.409 ↗	alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Arm,IBB,Arm_3	0.62	45.0	3.19e-01	93.7%	23.8%
5023303	601.4.1.0 ↗	alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains	0.62	52.0	4.60e-01	92.4%	66.1%
3367300	101.1.10.7 ↗	alpha arrays › HTH › HTH › Cyclin-like › Cyclin_C	0.61	50.0	3.93e-01	87.3%	66.9%
5034573	4156.1.1.6 ↗	alpha arrays › Sec63 N-terminal subdomain-like › Sec63 N-terminal subdomain-like › Sec63 N-terminal subdomain-like › Helicase_dom4_arc	0.61	52.0	4.30e-01	96.2%	90.3%
3271444	109.4.1.0 ↗	alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat	0.61	50.0	3.43e-01	88.6%	33.6%
3707094	109.4.1.628 ↗	alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Sec7-like_HUS	0.60	52.0	3.70e-01	98.7%	44.3%
3345666	109.1.1.7 ↗	alpha superhelices › Repetitive alpha hairpins › Glutathione S-transferase (GST)-C › Glutathione S-transferase (GST)-C › GST_C_3	0.60	53.0	4.46e-01	100.0%	69.6%
None	—		0.60	51.0	3.83e-01	97.5%	45.5%
4128901	109.4.1.158 ↗	alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › ERAP1_C	0.59	50.0	3.46e-01	93.7%	35.6%
3239387	2485.1.1.0 ↗	a+b three layers › Thioredoxin-like › Thioredoxin-like › Thioredoxin-like	0.59	51.0	3.83e-01	100.0%	45.2%
4324037	109.4.1.681 ↗	alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Fungal_trans_2	0.59	49.0	3.16e-01	93.7%	23.0%
3174622	4967.1.1.0 ↗	alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases	0.59	50.0	4.14e-01	97.5%	85.2%
4485359	103.2.1.0 ↗	alpha arrays › RuvA-C › ATP cone › ATP cone	0.58	39.0	3.73e-01	91.1%	57.9%
3368223	192.29.1.0 ↗	alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding)	0.58	50.0	3.65e-01	96.2%	60.5%
3871543	604.1.1.0 ↗	alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat	0.58	50.0	4.23e-01	96.2%	73.8%
3243599	601.1.2.0 ↗	alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608)	0.58	49.0	4.44e-01	100.0%	79.1%
3841673	604.1.1.1 ↗	alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin	0.57	48.0	4.51e-01	93.7%	91.0%
3784566	604.1.1.191 ↗	alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › PF29057	0.57	45.0	4.19e-01	87.3%	85.0%
3755130	604.1.1.1 ↗	alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin	0.56	45.0	4.09e-01	86.1%	81.9%
3168467	109.4.1.623 ↗	alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Cnd1	0.56	48.0	3.36e-01	94.9%	41.2%
3250251	4967.1.1.16 ↗	alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › TERT_C	0.56	49.0	3.63e-01	100.0%	75.9%
3964840	3636.1.1.0 ↗	a+b two layers › XPD arch domain › XPD arch domain › XPD arch domain	0.56	47.0	3.69e-01	97.5%	68.1%
3789673	109.4.1.0 ↗	alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat	0.56	48.0	3.39e-01	97.5%	70.8%
3628914	109.4.1.0 ↗	alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat	0.55	47.0	2.87e-01	93.7%	29.6%
3168872	192.15.1.1 ↗	alpha bundles › Long alpha-hairpin › Endosomal sorting complex assembly domains › Endosomal sorting complex assembly domains › VPS28	0.54	45.0	4.12e-01	92.4%	81.0%
5019542	622.4.1.67 ↗	alpha bundles › YvfG-like › Mite allergen Der p 5-related › Mite allergen Der p 5-related › DUF5518	0.54	45.0	4.21e-01	93.7%	87.9%
3965294	3558.1.1.0 ↗	alpha arrays › HSDR subunit helical domain › HSDR subunit helical domain › HSDR subunit helical domain	0.53	42.0	4.00e-01	86.1%	77.9%
5044421	592.2.1.0 ↗	alpha arrays › PWI domain-like › YugE-like › YugE-like	0.53	37.0	3.72e-01	100.0%	72.5%
3172916	109.4.1.158 ↗	alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › ERAP1_C	0.52	41.0	2.79e-01	86.1%	24.1%
3272035	109.21.1.2 ↗	alpha superhelices › Repetitive alpha hairpins › Nucleoporin NUP85/Nucleoporin NUP145 C-terminal domain › Nucleoporin NUP85/Nucleoporin NUP145 C-terminal domain › Nup96	0.52	46.0	2.74e-01	100.0%	52.1%

D3 medium residues 112-174

PDB

Domain cluster: rep: HC-Pro_protein__YP_006405405__Basella_rugose_mosaic_virus__373398__D110-165

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF00851.25 best	Peptidase_C6	27.3	2.50e-06	100.0%	13.9%

D4 medium residues 209-266

PDB

Domain cluster: rep: helper_component_protein__YP_006280732__Tomato_necrotic_stunt_virus__1176153__D223-273

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF00851.25 best	Peptidase_C6	38.3	1.20e-09	100.0%	12.5%