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HC-Pro_protein
Euk-VirChilli_ringspot_virus
HC-Pro_protein__YP_006423986__Chilli_ringspot_virus__414528
Identity
- Accession:
- YP_006423986 ↗
- Protein ID:
- HC-Pro_protein
- Kingdom:
- euk
Quality
85.4
mean pLDDT
Taxonomy
Orthornavirae›
Pisuviricota›
Stelpaviricetes›
Patatavirales›
Potyviridae›
Potyvirus›
Chilli_ringspot_virus
TaxID: 414528
Cluster
View cluster (80 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
medium
residues 113-178
Domain cluster:
rep: HC-Pro_protein__YP_006405405__Basella_rugose_mosaic_virus__373398__D110-165
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00851.25 best | Peptidase_C6 | 39.4 | 5.30e-10 | 98.5% | 13.6% |
CATH (37)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 6r1nA01 | 1.10.287.40 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain | 0.87 | 64.0 | 5.39e-01 | 77.3% | 55.3% |
| 1u7lA02 | 1.20.1460.10 | Mainly Alpha › Up-down Bundle › subunit c (vma5p) of the yeast v-atpase, domain 2 › subunit c (vma5p) of the yeast v-atpase, domain 2 | 0.85 | 62.0 | 4.36e-01 | 75.8% | 56.8% |
| 3qo8A01 | 1.10.287.40 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain | 0.84 | 61.0 | 5.17e-01 | 77.3% | 52.8% |
| 3r84A00 | 1.10.287.3490 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.83 | 61.0 | 5.64e-01 | 77.3% | 65.4% |
| 1sumB02 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.82 | 60.0 | 4.90e-01 | 77.3% | 48.3% |
| 1zkeA00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.81 | 59.0 | 5.46e-01 | 75.8% | 84.0% |
| 4nb5B02 | 1.10.287.160 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat | 0.81 | 56.0 | 5.72e-01 | 72.7% | 85.9% |
| 2ic6A00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.80 | 58.0 | 5.69e-01 | 77.3% | 76.1% |
| 1zoyD00 | 1.20.1300.10 | Mainly Alpha › Up-down Bundle › 3 helical TM bundles of succinate and fumarate reductases › Fumarate reductase/succinate dehydrogenase, transmembrane subunit | 0.79 | 57.0 | 4.88e-01 | 75.8% | 50.0% |
| 1ku9A02 | 1.10.287.450 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.77 | 54.0 | 5.50e-01 | 74.2% | 82.8% |
| 5lnkJ01 | 1.20.120.1200 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › NADH-ubiquinone/plastoquinone oxidoreductase chain 6, subunit NuoJ | 0.74 | 52.0 | 3.83e-01 | 74.2% | 76.3% |
| 6xj1A01 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.73 | 53.0 | 3.57e-01 | 77.3% | 21.6% |
| 1k20A01 | 3.90.1640.10 | Alpha Beta › Alpha-Beta Complex › inorganic pyrophosphatase (n-terminal core) › inorganic pyrophosphatase (n-terminal core) | 0.73 | 53.0 | 3.77e-01 | 77.3% | 70.0% |
| 2lpeA01 | 6.10.140.1120 | Special › Helix non-globular › Helix Hairpins › | 0.72 | 54.0 | 5.13e-01 | 80.3% | 74.4% |
| 2hujA00 | 1.20.120.440 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › YppE-like | 0.72 | 61.0 | 4.97e-01 | 95.5% | 67.2% |
| 3unoE00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.71 | 53.0 | 3.93e-01 | 78.8% | 60.5% |
| 3layF00 | 1.20.120.1490 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.71 | 52.0 | 4.96e-01 | 78.8% | 74.4% |
| 6iknD01 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.71 | 52.0 | 3.43e-01 | 77.3% | 19.5% |
| 3eslA01 | 1.20.58.2070 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.69 | 47.0 | 4.57e-01 | 71.2% | 68.0% |
| 3favD00 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.68 | 49.0 | 4.65e-01 | 75.8% | 71.8% |
| 3s84A02 | 1.20.120.20 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein | 0.67 | 48.0 | 3.58e-01 | 74.2% | 64.3% |
| 1tj7A01 | 1.10.275.10 | Mainly Alpha › Orthogonal Bundle › Fumarase C; Chain B, domain 1 › Fumarase/aspartase (N-terminal domain) | 0.67 | 46.0 | 3.89e-01 | 71.2% | 46.7% |
| 1vt0M02 | 1.10.1740.160 | Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › | 0.66 | 54.0 | 4.81e-01 | 87.9% | 96.7% |
| 1vt0k00 | 1.10.3230.20 | Mainly Alpha › Orthogonal Bundle › Hypothetical protein yqbg › P22 tail accessory factor (Gp4) | 0.65 | 53.0 | 4.23e-01 | 93.9% | 61.4% |
| 2bl2A00 | 1.20.120.610 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › lithium bound rotor ring of v- atpase | 0.64 | 52.0 | 3.99e-01 | 89.4% | 81.4% |
| 7zm7601 | 1.20.120.1200 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › NADH-ubiquinone/plastoquinone oxidoreductase chain 6, subunit NuoJ | 0.64 | 55.0 | 4.17e-01 | 100.0% | 44.9% |
| 2yevA02 | 1.10.287.70 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.63 | 45.0 | 4.42e-01 | 77.3% | 70.3% |
| 1f45B00 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.62 | 54.0 | 4.24e-01 | 93.9% | 62.4% |
| 8befJ01 | 1.20.120.1200 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › NADH-ubiquinone/plastoquinone oxidoreductase chain 6, subunit NuoJ | 0.62 | 53.0 | 4.05e-01 | 100.0% | 44.1% |
| 3hl6A02 | 1.20.58.700 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.62 | 48.0 | 4.13e-01 | 89.4% | 52.2% |
| 1vibA00 | 1.10.287.120 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Neurotoxin B-IV-like | 0.60 | 38.0 | 4.08e-01 | 71.2% | 76.4% |
| 5u9nB00 | 1.20.920.10 | Mainly Alpha › Up-down Bundle › Histone Acetyltransferase; Chain A › Bromodomain-like | 0.57 | 48.0 | 4.08e-01 | 100.0% | 65.0% |
| 2bvlA01 | 1.20.58.1190 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.57 | 45.0 | 4.19e-01 | 90.9% | 72.1% |
| 6dcjA02 | 1.25.40.650 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.55 | 40.0 | 3.55e-01 | 80.3% | 53.8% |
| 4kx7A04 | 1.25.50.20 | Mainly Alpha › Alpha Horseshoe › Zincin-like fold › | 0.53 | 46.0 | 2.99e-01 | 100.0% | 35.0% |
| 1szhA02 | 1.10.150.370 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Caenorhabditis elegans Her-1, C-terminal domain | 0.53 | 40.0 | 3.71e-01 | 81.8% | 64.6% |
| 1sqgA01 | 1.10.940.10 | Mainly Alpha › Orthogonal Bundle › N-utilizing Substance Protein B Homolog; Chain A › NusB-like | 0.52 | 39.0 | 3.11e-01 | 80.3% | 41.8% |
ECOD (29)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3471712 | 604.8.1.0 ↗ | alpha bundles › Spectrin repeat-like › Smac/diablo › Smac/diablo | 0.86 | 64.0 | 5.03e-01 | 77.3% | 61.6% |
| 4507542 | 192.7.1.2 ↗ | alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N | 0.86 | 63.0 | 5.63e-01 | 77.3% | 57.8% |
| 3185917 | 375.1.9.12 ↗ | few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Zinc-nucleated domain of serine integrase › Wbp11 | 0.86 | 60.0 | 5.44e-01 | 72.7% | 60.0% |
| 4961961 | 605.1.1.1 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA | 0.85 | 60.0 | 5.77e-01 | 74.2% | 69.3% |
| 3927738 | 632.8.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › alpha-2-Macroglobulin receptor associated protein (RAP) domain 1 › alpha-2-Macroglobulin receptor associated protein (RAP) domain 1 | 0.85 | 62.0 | 5.44e-01 | 77.3% | 55.8% |
| 4015612 | 616.1.1.0 ↗ | alpha arrays › S15/NS1 RNA-binding domain › S15/NS1 RNA-binding domain › S15/NS1 RNA-binding domain | 0.84 | 59.0 | 5.37e-01 | 72.7% | 60.0% |
| 3840952 | 601.19.1.39 ↗ | alpha bundles › Four-helical up-and-down bundle › Apolipoprotein › Apolipoprotein › LIN9_C | 0.84 | 62.0 | 5.91e-01 | 77.3% | 80.0% |
| 3326073 | 3291.1.1.0 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related | 0.83 | 62.0 | 5.10e-01 | 77.3% | 48.2% |
| 3477418 | 4992.1.1.12 ↗ | extended segments › RelB-like › RelB-like › RelB-like › LIN9_C | 0.83 | 61.0 | 5.35e-01 | 77.3% | 63.2% |
| 3906191 | 4323.1.1.1 ↗ | alpha bundles › helical bundle domain in vacuolar ATP synthase subunit C › helical bundle domain in vacuolar ATP synthase subunit C › helical bundle domain in vacuolar ATP synthase subunit C › V_ATPase_I | 0.83 | 61.0 | 4.55e-01 | 77.3% | 34.2% |
| 4042824 | 192.8.1.0 ↗ | alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain | 0.83 | 61.0 | 5.72e-01 | 77.3% | 70.0% |
| 4315986 | 192.7.1.2 ↗ | alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N | 0.83 | 61.0 | 5.45e-01 | 77.3% | 56.7% |
| 1879027 | 244.1.1.6 ↗ | a+b two layers › FAD-linked reductases, C-terminal domain-like › FAD-linked reductases-C › FAD-linked reductases-C › Amino_oxidase | 0.83 | 61.0 | 3.69e-01 | 77.3% | 13.9% |
| 3596744 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.83 | 61.0 | 5.56e-01 | 77.3% | 62.4% |
| 3942242 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.82 | 60.0 | 4.58e-01 | 75.8% | 52.9% |
| 3693258 | 604.7.1.1 ↗ | alpha bundles › Spectrin repeat-like › Tubulin chaperone cofactor A › Tubulin chaperone cofactor A › TBCA | 0.82 | 60.0 | 4.99e-01 | 77.3% | 72.7% |
| 3712411 | 3939.1.1.0 ↗ | alpha duplicates or obligate multimers › XRCC4 C-terminal oligomerization domain › XRCC4 C-terminal oligomerization domain › XRCC4 C-terminal oligomerization domain | 0.81 | 59.0 | 3.92e-01 | 77.3% | 21.6% |
| 2665702 | 3146.1.1.3 ↗ | a+b complex topology › gH main domain › gH main domain › gH main domain › Phage_glycop_gL | 0.81 | 61.0 | 4.94e-01 | 78.8% | 75.7% |
| 4595410 | 192.8.1.0 ↗ | alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain | 0.78 | 56.0 | 5.70e-01 | 78.8% | 76.9% |
| 4819006 | 2004.1.1.5 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ABC_tran | 0.76 | 55.0 | 3.60e-01 | 77.3% | 19.0% |
| 4013459 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.75 | 55.0 | 3.33e-01 | 77.3% | 12.9% |
| 3929573 | 192.8.1.395 ↗ | alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain › CHDCT2 | 0.74 | 63.0 | 5.71e-01 | 90.9% | 100.0% |
| 3690135 | 616.1.1.0 ↗ | alpha arrays › S15/NS1 RNA-binding domain › S15/NS1 RNA-binding domain › S15/NS1 RNA-binding domain | 0.73 | 64.0 | 5.29e-01 | 98.5% | 65.8% |
| 3929910 | 101.1.2.507 ↗ | alpha arrays › HTH › HTH › winged helix domain › HTH_TANC1 | 0.71 | 53.0 | 3.94e-01 | 77.3% | 60.0% |
| 3684923 | 109.4.1.681 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Fungal_trans_2 | 0.71 | 62.0 | 3.80e-01 | 100.0% | 17.3% |
| 3215086 | 188.1.1.1 ↗ | alpha arrays › Nuclear receptor ligand-binding domain › Nuclear receptor ligand-binding domain › Nuclear receptor ligand-binding domain › Hormone_recep | 0.69 | 55.0 | 3.74e-01 | 87.9% | 26.7% |
| 3640857 | 109.4.1.356 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Fungal_trans | 0.67 | 59.0 | 3.50e-01 | 100.0% | 39.4% |
| 3942635 | 4156.1.1.4 ↗ | alpha arrays › Sec63 N-terminal subdomain-like › Sec63 N-terminal subdomain-like › Sec63 N-terminal subdomain-like › HA2_C | 0.66 | 45.0 | 3.50e-01 | 71.2% | 64.8% |
| 3809254 | 509.1.1.1 ↗ | alpha bundles › PAH2 domain › PAH2 domain › PAH2 domain › PAH | 0.50 | 37.0 | 3.78e-01 | 78.8% | 81.5% |
D2
medium
residues 181-269_314-340
Domain cluster:
rep: HC-Pro__YP_001936179__Verbena_virus_Y__515446__D186-209_223-267_313-337
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00851.25 best | Peptidase_C6 | 64.3 | 1.50e-17 | 76.7% | 17.5% |
D3
medium
residues 270-313_341-458
Domain cluster:
rep: HC-Pro_protein__YP_006590094__Chinese_yam_necrotic_mosaic_virus__128818__D95-261
Pfam (2)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00851.25 best | Peptidase_C6 | 176.9 | 1.00e-51 | 74.7% | 27.1% |
| PF00851.25 | Peptidase_C6 | 27.8 | 1.80e-06 | 27.2% | 8.6% |
CATH (3)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3rnvA00 | 3.90.70.150 | Alpha Beta › Alpha-Beta Complex › Cathepsin B; Chain A › Helper component proteinase | 0.92 | 66.0 | 7.61e-01 | 72.8% | 95.9% |
| 3ifuA02 | 3.90.70.60 | Alpha Beta › Alpha-Beta Complex › Cathepsin B; Chain A › Porcine arterivirus-type cysteine proteinase alpha domain | 0.59 | 40.0 | 4.64e-01 | 77.2% | 97.4% |
| 2lwdA00 | 1.10.533.10 | Mainly Alpha › Orthogonal Bundle › Death Domain, Fas › Death Domain, Fas | 0.56 | 29.0 | 3.65e-01 | 75.3% | 82.3% |
ECOD (2)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 185514 | 219.1.1.7 ↗ | a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Peptidase_C6 | 0.92 | 66.0 | 7.61e-01 | 72.8% | 95.9% |
| 7410 | 219.1.1.64 ↗ | a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › PMT_C3 | 0.50 | 39.0 | 3.74e-01 | 82.1% | 90.6% |