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HC-Pro_protein
Euk-VirSweet_potato_virus_2
HC-Pro_protein__YP_006438189__Sweet_potato_virus_2__453050
Identity
- Accession:
- YP_006438189 ↗
- Protein ID:
- HC-Pro_protein
- Kingdom:
- euk
Quality
84.7
mean pLDDT
Taxonomy
Orthornavirae›
Pisuviricota›
Stelpaviricetes›
Patatavirales›
Potyviridae›
Potyvirus›
Sweet_potato_virus_2
TaxID: 453050
Cluster
View cluster (80 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 119-180
Domain cluster:
rep: HC-Pro_protein__YP_006405405__Basella_rugose_mosaic_virus__373398__D110-165
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00851.25 best | Peptidase_C6 | 42.6 | 5.70e-11 | 100.0% | 13.4% |
D2
medium
residues 32-118
Domain cluster:
rep: HC-Pro__YP_009252411__Tobacco_mosqueado_virus__1792583__D31-64_66-104
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00851.25 best | Peptidase_C6 | 30.8 | 2.20e-07 | 100.0% | 19.3% |
CATH (27)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2pqrA01 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.67 | 43.0 | 4.21e-01 | 83.9% | 60.2% |
| 1kpgD00 | 3.40.50.150 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 | 0.63 | 50.0 | 3.52e-01 | 87.4% | 91.2% |
| 4f92B10 | 1.10.3380.10 | Mainly Alpha › Orthogonal Bundle › Sec63 N-terminal domain-like fold › Sec63 N-terminal domain-like domain | 0.61 | 49.0 | 4.15e-01 | 85.1% | 83.9% |
| 2jqqA00 | 1.20.58.1240 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.60 | 51.0 | 4.26e-01 | 95.4% | 53.2% |
| 3p5nA00 | 1.10.1760.20 | Mainly Alpha › Orthogonal Bundle › Arp2/3 complex 21 kDa subunit ARPC3 › | 0.58 | 46.0 | 3.76e-01 | 86.2% | 47.6% |
| 3nivC02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.58 | 46.0 | 4.15e-01 | 87.4% | 72.6% |
| 4oydB00 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.58 | 47.0 | 4.30e-01 | 89.7% | 93.2% |
| 2v6kA02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.58 | 46.0 | 4.06e-01 | 87.4% | 70.0% |
| 2odmA00 | 1.10.287.750 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › SO2669-like | 0.57 | 47.0 | 4.87e-01 | 92.0% | 100.0% |
| 2uubT00 | 1.20.58.110 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Ribosomal protein S20 | 0.56 | 44.0 | 4.32e-01 | 92.0% | 76.8% |
| 1yxrA01 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.56 | 43.0 | 4.58e-01 | 88.5% | 98.6% |
| 2ys8A00 | 1.10.287.110 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › DnaJ domain | 0.56 | 47.0 | 4.70e-01 | 96.6% | 90.0% |
| 1quuA01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.55 | 48.0 | 4.30e-01 | 98.9% | 90.5% |
| 2ld7B00 | 1.20.1160.11 | Mainly Alpha › Up-down Bundle › Paired amphipathic helix 2 (pah2 repeat) › Paired amphipathic helix | 0.55 | 35.0 | 3.67e-01 | 88.5% | 73.3% |
| 2radA03 | 1.20.1440.30 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › Biosynthetic Protein domain | 0.55 | 46.0 | 4.11e-01 | 95.4% | 70.1% |
| 1s35A02 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.54 | 47.0 | 4.42e-01 | 98.9% | 100.0% |
| 2hk0A00 | 3.20.20.150 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Divalent-metal-dependent TIM barrel enzymes | 0.54 | 42.0 | 2.93e-01 | 83.9% | 39.6% |
| 1iyhB02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.54 | 43.0 | 4.09e-01 | 89.7% | 81.5% |
| 3pe0A02 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.53 | 43.0 | 4.12e-01 | 90.8% | 89.6% |
| 6vudA01 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.53 | 46.0 | 4.34e-01 | 97.7% | 100.0% |
| 2vixA03 | 1.20.1280.240 | Mainly Alpha › Up-down Bundle › Monooxygenase › | 0.53 | 45.0 | 4.14e-01 | 94.3% | 95.6% |
| 3pe0A01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.52 | 44.0 | 4.26e-01 | 94.3% | 100.0% |
| 3fr3B02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.52 | 42.0 | 3.95e-01 | 92.0% | 72.2% |
| 1vw4L02 | 1.10.246.170 | Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › | 0.52 | 35.0 | 3.56e-01 | 77.0% | 69.4% |
| 3k7dA02 | 3.30.460.10 | Alpha Beta › 2-Layer Sandwich › Beta Polymerase; domain 2 › Beta Polymerase, domain 2 | 0.52 | 42.0 | 3.11e-01 | 90.8% | 72.8% |
| 3e4bA00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.51 | 41.0 | 2.66e-01 | 87.4% | 23.3% |
| 1q16C01 | 1.20.950.20 | Mainly Alpha › Up-down Bundle › Fumarate Reductase Cytochrome B subunit › Transmembrane di-heme cytochromes, Chain C | 0.51 | 43.0 | 3.25e-01 | 93.1% | 52.8% |
ECOD (17)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4344916 | 109.4.1.1498 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › ATP13, PF30078 | 0.63 | 48.0 | 3.07e-01 | 100.0% | 16.4% |
| 4201754 | 604.9.1.1 ↗ | alpha bundles › Spectrin repeat-like › Ribosomal protein S20 › Ribosomal protein S20 › Ribosomal_S20p | 0.60 | 47.0 | 4.59e-01 | 92.0% | 77.9% |
| 3373039 | 192.17.1.0 ↗ | alpha bundles › Long alpha-hairpin › Rabenosyn-5 Rab-binding domain-like › Rabenosyn-5 Rab-binding domain-like | 0.60 | 47.0 | 4.33e-01 | 86.2% | 71.3% |
| 3890439 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.58 | 51.0 | 4.60e-01 | 100.0% | 89.6% |
| 5047419 | 1075.1.2.0 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › MacB transmembrane domain | 0.58 | 45.0 | 3.77e-01 | 86.2% | 75.0% |
| 3534085 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.57 | 50.0 | 4.60e-01 | 97.7% | 91.3% |
| 3484929 | 604.1.1.1 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin | 0.56 | 45.0 | 4.36e-01 | 88.5% | 97.0% |
| 5044715 | 633.6.1.1 ↗ | alpha bundles › Bromodomain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA_dh_1 | 0.56 | 47.0 | 3.80e-01 | 94.3% | 85.3% |
| 3389546 | 604.1.1.1 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin | 0.55 | 45.0 | 4.71e-01 | 92.0% | 97.5% |
| 3755130 | 604.1.1.1 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin | 0.55 | 46.0 | 4.33e-01 | 92.0% | 98.1% |
| 3758972 | 604.1.1.1 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin | 0.55 | 48.0 | 4.47e-01 | 97.7% | 97.3% |
| 3497641 | 604.1.1.1 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin | 0.55 | 45.0 | 4.31e-01 | 90.8% | 100.0% |
| 3306390 | 604.9.1.1 ↗ | alpha bundles › Spectrin repeat-like › Ribosomal protein S20 › Ribosomal protein S20 › Ribosomal_S20p | 0.54 | 46.0 | 4.37e-01 | 96.6% | 84.8% |
| 59125 | 109.1.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › Glutathione S-transferase (GST)-C › Glutathione S-transferase (GST)-C | 0.53 | 43.0 | 3.85e-01 | 90.8% | 70.1% |
| 3458610 | 101.1.10.13 ↗ | alpha arrays › HTH › HTH › Cyclin-like › DUF3452 | 0.53 | 40.0 | 3.55e-01 | 87.4% | 55.4% |
| 3559718 | 604.1.1.1 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin | 0.52 | 45.0 | 4.16e-01 | 95.4% | 93.6% |
| 3584182 | 604.9.1.18 ↗ | alpha bundles › Spectrin repeat-like › Ribosomal protein S20 › Ribosomal protein S20 › Zip | 0.50 | 38.0 | 3.92e-01 | 85.1% | 91.8% |
D3
medium
residues 295-458
Domain cluster:
rep: HC-Pro_protein__YP_006590094__Chinese_yam_necrotic_mosaic_virus__128818__D95-261
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00851.25 best | Peptidase_C6 | 241.7 | 2.20e-71 | 100.0% | 37.3% |