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HC-Pro_protein
Euk-VirWild_onion_symptomless_virus
HC-Pro_protein__YP_009259513__Wild_onion_symptomless_virus__1862127
Identity
- Accession:
- YP_009259513 ↗
- Protein ID:
- HC-Pro_protein
- Kingdom:
- euk
Quality
82.5
mean pLDDT
Taxonomy
Orthornavirae›
Pisuviricota›
Stelpaviricetes›
Patatavirales›
Potyviridae›
Potyvirus›
Wild_onion_symptomless_virus
TaxID: 1862127
Cluster
View cluster (80 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 116-173
Domain cluster:
rep: HC-Pro_protein__YP_006405405__Basella_rugose_mosaic_virus__373398__D110-165
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00851.25 best | Peptidase_C6 | 31.4 | 1.40e-07 | 100.0% | 13.2% |
D2
medium
residues 32-115
Domain cluster:
rep: HC-Pro__YP_009252411__Tobacco_mosqueado_virus__1792583__D31-64_66-104
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00851.25 best | Peptidase_C6 | 25.3 | 1.00e-05 | 100.0% | 15.7% |
CATH (48)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3k6tB00 | 1.20.5.4010 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › | 0.79 | 43.0 | 5.64e-01 | 76.2% | 93.9% |
| 3qwwA03 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.73 | 56.0 | 4.25e-01 | 94.0% | 35.6% |
| 2ondA00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.72 | 57.0 | 3.83e-01 | 95.2% | 23.1% |
| 2yjkC00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.71 | 65.0 | 5.24e-01 | 100.0% | 94.9% |
| 3oxfA05 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.69 | 49.0 | 5.17e-01 | 89.3% | 82.7% |
| 4y6cA00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.67 | 50.0 | 3.70e-01 | 88.1% | 31.1% |
| 4l8iB00 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.66 | 56.0 | 5.09e-01 | 92.9% | 93.8% |
| 2v6kA02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.66 | 56.0 | 4.80e-01 | 91.7% | 70.8% |
| 2d9dA00 | 1.20.58.120 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain | 0.66 | 58.0 | 5.74e-01 | 97.6% | 93.3% |
| 4dmvA01 | 1.20.58.1190 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.66 | 53.0 | 5.28e-01 | 97.6% | 87.1% |
| 2ijqA00 | 1.10.3450.10 | Mainly Alpha › Orthogonal Bundle › Hyaluronidase domain-like › TTHA0068-like | 0.66 | 46.0 | 3.78e-01 | 83.3% | 42.1% |
| 3nivC02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.65 | 55.0 | 4.80e-01 | 91.7% | 74.2% |
| 2mtqA00 | 1.20.58.130 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.65 | 53.0 | 5.62e-01 | 94.0% | 100.0% |
| 6fndA01 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.65 | 48.0 | 3.69e-01 | 91.7% | 35.5% |
| 4a25B01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.65 | 56.0 | 4.59e-01 | 98.8% | 90.1% |
| 2yfaA02 | 1.20.1440.210 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › | 0.64 | 55.0 | 4.98e-01 | 95.2% | 70.7% |
| 2clbA01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.63 | 56.0 | 4.56e-01 | 98.8% | 95.6% |
| 2aj4B03 | 1.20.1440.340 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › | 0.63 | 54.0 | 4.33e-01 | 92.9% | 75.9% |
| 2oduA02 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.63 | 57.0 | 5.27e-01 | 98.8% | 97.1% |
| 1he8A03 | 1.25.40.70 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Phosphatidylinositol 3-kinase, accessory domain (PIK) | 0.63 | 42.0 | 3.90e-01 | 91.7% | 52.3% |
| 1ugoA00 | 1.20.58.120 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain | 0.63 | 55.0 | 5.23e-01 | 95.2% | 85.9% |
| 4kb2A01 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.61 | 53.0 | 4.89e-01 | 95.2% | 95.4% |
| 3ujpB01 | 3.40.50.1980 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Nitrogenase molybdenum iron protein domain | 0.61 | 50.0 | 4.17e-01 | 90.5% | 97.3% |
| 1hs7A00 | 1.20.58.70 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.60 | 53.0 | 5.13e-01 | 98.8% | 97.9% |
| 3axjB02 | 1.20.58.200 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 2 | 0.60 | 50.0 | 5.06e-01 | 91.7% | 91.8% |
| 3axsA01 | 3.40.50.150 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 | 0.60 | 50.0 | 3.39e-01 | 92.9% | 98.8% |
| 4oydB00 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.60 | 50.0 | 4.54e-01 | 92.9% | 92.3% |
| 1s35A02 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.60 | 52.0 | 4.79e-01 | 97.6% | 96.4% |
| 3pe0A02 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.59 | 50.0 | 4.64e-01 | 92.9% | 91.5% |
| 5k29A00 | 1.20.920.10 | Mainly Alpha › Up-down Bundle › Histone Acetyltransferase; Chain A › Bromodomain-like | 0.59 | 48.0 | 4.58e-01 | 91.7% | 76.3% |
| 1cunA01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.59 | 52.0 | 4.86e-01 | 96.4% | 100.0% |
| 3edvB01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.59 | 53.0 | 4.52e-01 | 100.0% | 79.4% |
| 8ek4A01 | 1.20.120.20 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein | 0.59 | 52.0 | 4.54e-01 | 100.0% | 97.7% |
| 6vudA01 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.59 | 51.0 | 4.73e-01 | 97.6% | 100.0% |
| 2uubT00 | 1.20.58.110 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Ribosomal protein S20 | 0.58 | 47.0 | 4.53e-01 | 95.2% | 76.8% |
| 3lbxB01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.58 | 51.0 | 4.71e-01 | 97.6% | 95.3% |
| 3cx3B01 | 3.40.50.1980 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Nitrogenase molybdenum iron protein domain | 0.58 | 50.0 | 4.12e-01 | 96.4% | 98.7% |
| 4nuuB02 | 1.20.58.830 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.58 | 48.0 | 4.28e-01 | 92.9% | 93.5% |
| 4acoA01 | 1.10.150.130 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Tyrosine recombinase, N-terminal domain | 0.57 | 49.0 | 4.48e-01 | 95.2% | 75.5% |
| 4v1gA00 | 1.20.20.10 | Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C | 0.56 | 39.0 | 3.91e-01 | 73.8% | 70.6% |
| 2i2xB01 | 1.10.1240.10 | Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › Methionine synthase domain | 0.56 | 49.0 | 4.63e-01 | 97.6% | 98.0% |
| 3fb2A01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.56 | 49.0 | 4.56e-01 | 98.8% | 100.0% |
| 2juaA00 | 1.20.1480.30 | Mainly Alpha › Up-down Bundle › hypothetical protein mp506/mpn330, domain 1 › Designed four-helix bundle protein | 0.55 | 47.0 | 4.47e-01 | 95.2% | 80.4% |
| 7cfmR01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.55 | 46.0 | 3.35e-01 | 96.4% | 78.3% |
| 5cmyA00 | 1.25.40.90 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.54 | 44.0 | 3.75e-01 | 91.7% | 81.7% |
| 2ycdA02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.54 | 43.0 | 3.88e-01 | 88.1% | 70.9% |
| 2yogA00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.53 | 45.0 | 3.45e-01 | 94.0% | 40.1% |
| 1np7A02 | 1.25.40.80 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.53 | 43.0 | 3.85e-01 | 91.7% | 63.0% |
ECOD (35)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3969284 | 633.28.1.2 ↗ | alpha bundles › Bromodomain-like › Tsi6 › Tsi6 › DUF4404 | 0.68 | 50.0 | 5.19e-01 | 92.9% | 82.5% |
| 4491518 | 7516.1.1.153 ↗ | a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Glycos_transf_2, Glyco_transf_8 | 0.67 | 57.0 | 3.46e-01 | 94.0% | 38.7% |
| 3605710 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.66 | 55.0 | 5.82e-01 | 91.7% | 100.0% |
| 3703063 | 604.3.1.0 ↗ | alpha bundles › Spectrin repeat-like › BAG domain › BAG domain | 0.66 | 55.0 | 5.34e-01 | 92.9% | 97.9% |
| 3640330 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.65 | 55.0 | 4.62e-01 | 91.7% | 67.9% |
| 3529996 | 109.4.1.198 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_12 | 0.65 | 50.0 | 3.79e-01 | 92.9% | 35.8% |
| 3277087 | 192.4.1.0 ↗ | alpha bundles › Long alpha-hairpin › Ribosomal protein L29 (L29p) › Ribosomal protein L29 (L29p) | 0.63 | 52.0 | 4.95e-01 | 94.0% | 76.8% |
| 3599875 | 3291.1.1.0 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related | 0.63 | 50.0 | 4.27e-01 | 96.4% | 52.1% |
| 5067572 | 604.5.1.0 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) | 0.62 | 56.0 | 5.17e-01 | 98.8% | 98.1% |
| 3778716 | 604.1.1.1 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin | 0.62 | 51.0 | 4.80e-01 | 91.7% | 91.4% |
| 3247875 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.61 | 47.0 | 3.87e-01 | 95.2% | 44.4% |
| 3271444 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.60 | 53.0 | 3.70e-01 | 96.4% | 73.5% |
| 3985371 | 5054.1.1.8 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › Ion_trans_2 | 0.60 | 53.0 | 3.81e-01 | 95.2% | 39.1% |
| 3484907 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.60 | 52.0 | 4.69e-01 | 98.8% | 87.5% |
| 3904075 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.59 | 52.0 | 4.76e-01 | 96.4% | 99.1% |
| 3396401 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.59 | 52.0 | 4.70e-01 | 98.8% | 99.1% |
| 3398622 | 604.6.1.1 ↗ | alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain › GAT | 0.59 | 49.0 | 4.88e-01 | 94.0% | 96.7% |
| 3909893 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.59 | 53.0 | 4.45e-01 | 100.0% | 100.0% |
| 3701328 | 109.4.1.1362 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › COG5_C | 0.59 | 48.0 | 4.21e-01 | 98.8% | 59.2% |
| 3518885 | 633.1.1.1 ↗ | alpha bundles › Bromodomain-like › Bromodomain › Bromodomain › Bromodomain | 0.58 | 47.0 | 4.74e-01 | 96.4% | 89.4% |
| 3171100 | 603.1.1.100 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › PF27017 | 0.58 | 49.0 | 4.67e-01 | 94.0% | 94.0% |
| 1019380 | 604.5.1.2 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU | 0.58 | 50.0 | 4.67e-01 | 98.8% | 96.3% |
| 3841673 | 604.1.1.1 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin | 0.57 | 48.0 | 4.54e-01 | 91.7% | 96.0% |
| 3930855 | 604.1.1.1 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin | 0.57 | 50.0 | 4.60e-01 | 97.6% | 99.1% |
| 3581268 | 604.1.1.104 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › ANC1_spectrin | 0.57 | 48.0 | 4.64e-01 | 94.0% | 100.0% |
| 3484929 | 604.1.1.1 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin | 0.57 | 48.0 | 4.57e-01 | 94.0% | 97.0% |
| 5001522 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.57 | 48.0 | 4.55e-01 | 95.2% | 98.1% |
| 4999401 | 4995.1.1.0 ↗ | alpha arrays › Methionine synthase domain-like › Methionine synthase domain-like › Methionine synthase domain-like | 0.56 | 38.0 | 3.86e-01 | 70.2% | 100.0% |
| 3713209 | 192.2.1.0 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin | 0.56 | 39.0 | 3.64e-01 | 72.6% | 65.7% |
| 3782809 | 603.1.1.17 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › SNARE | 0.56 | 45.0 | 3.54e-01 | 89.3% | 61.1% |
| 4485359 | 103.2.1.0 ↗ | alpha arrays › RuvA-C › ATP cone › ATP cone | 0.54 | 37.0 | 3.59e-01 | 91.7% | 62.1% |
| 3287159 | 5041.1.1.0 ↗ | extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C | 0.54 | 44.0 | 4.35e-01 | 89.3% | 95.6% |
| 3784313 | 103.2.1.2 ↗ | alpha arrays › RuvA-C › ATP cone › ATP cone › ATP-cone | 0.54 | 36.0 | 3.60e-01 | 89.3% | 65.6% |
| 869286 | 5069.1.3.4 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits › CybS | 0.53 | 36.0 | 3.20e-01 | 70.2% | 54.3% |
| 3678021 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.51 | 41.0 | 3.26e-01 | 90.5% | 69.2% |
D3
medium
residues 273-458
Domain cluster:
rep: HC-Pro_protein__YP_006590094__Chinese_yam_necrotic_mosaic_virus__128818__D95-261
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00851.25 best | Peptidase_C6 | 239.8 | 8.30e-71 | 99.5% | 41.6% |