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HC-Pro_protein
Euk-VirKonjac_mosaic_virus
HC-Pro_protein__YP_529491__Konjac_mosaic_virus__322053
Identity
- Accession:
- YP_529491 ↗
- Protein ID:
- HC-Pro_protein
- Kingdom:
- euk
Quality
84.1
mean pLDDT
Taxonomy
Orthornavirae›
Pisuviricota›
Stelpaviricetes›
Patatavirales›
Potyviridae›
Potyvirus›
Konjac_mosaic_virus
TaxID: 322053
Cluster
View cluster (80 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 29-105
Domain cluster:
rep: HC-Pro__YP_009252411__Tobacco_mosqueado_virus__1792583__D31-64_66-104
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00851.25 best | Peptidase_C6 | 26.9 | 3.20e-06 | 97.4% | 11.4% |
CATH (41)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4jvyB00 | 3.30.1370.10 | Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › K Homology domain, type 1 | 0.85 | 44.0 | 3.18e-01 | 77.9% | 21.1% |
| 2d2sA01 | 1.20.58.1210 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Exo84p, N-terminal helical domain | 0.74 | 58.0 | 4.99e-01 | 97.4% | 55.2% |
| 3n71A03 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.72 | 51.0 | 3.65e-01 | 74.0% | 44.1% |
| 2pqrA01 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.71 | 49.0 | 4.62e-01 | 90.9% | 59.1% |
| 2yjkC00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.71 | 64.0 | 5.05e-01 | 100.0% | 88.5% |
| 3oxfA05 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.71 | 50.0 | 5.12e-01 | 93.5% | 76.0% |
| 2lseA00 | 1.20.120.1360 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.70 | 51.0 | 4.67e-01 | 93.5% | 58.4% |
| 3ceqA00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.69 | 52.0 | 3.59e-01 | 94.8% | 24.4% |
| 3r2kA00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.69 | 63.0 | 4.90e-01 | 98.7% | 82.5% |
| 4dmvA01 | 1.20.58.1190 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.68 | 54.0 | 5.26e-01 | 100.0% | 80.0% |
| 1xzpA02 | 1.20.120.430 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › tRNA modification GTPase MnmE domain 2 | 0.66 | 60.0 | 4.64e-01 | 100.0% | 73.5% |
| 2bvlA01 | 1.20.58.1190 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.66 | 54.0 | 5.21e-01 | 100.0% | 80.2% |
| 5haxA01 | 1.20.58.1780 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.64 | 58.0 | 4.03e-01 | 100.0% | 40.7% |
| 4pxoA02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.64 | 57.0 | 4.81e-01 | 100.0% | 73.3% |
| 2v6kA02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.63 | 57.0 | 4.80e-01 | 100.0% | 73.8% |
| 3ebbA00 | 1.25.10.10 | Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant | 0.63 | 44.0 | 3.08e-01 | 74.0% | 37.5% |
| 1ugoA00 | 1.20.58.120 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain | 0.62 | 57.0 | 5.22e-01 | 100.0% | 85.9% |
| 5l0wB01 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.61 | 45.0 | 3.78e-01 | 94.8% | 44.2% |
| 5o5jT00 | 1.20.58.110 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Ribosomal protein S20 | 0.61 | 50.0 | 4.88e-01 | 100.0% | 83.5% |
| 4qnsA00 | 1.20.920.10 | Mainly Alpha › Up-down Bundle › Histone Acetyltransferase; Chain A › Bromodomain-like | 0.61 | 50.0 | 4.48e-01 | 89.6% | 74.5% |
| 1s35A02 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.61 | 54.0 | 4.74e-01 | 97.4% | 86.4% |
| 5tqbB01 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.61 | 54.0 | 3.48e-01 | 97.4% | 82.8% |
| 3k2jA00 | 1.20.920.10 | Mainly Alpha › Up-down Bundle › Histone Acetyltransferase; Chain A › Bromodomain-like | 0.61 | 51.0 | 4.37e-01 | 92.2% | 66.1% |
| 4flbA00 | 1.25.40.90 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.60 | 44.0 | 3.70e-01 | 90.9% | 45.8% |
| 3hmfA00 | 1.20.920.10 | Mainly Alpha › Up-down Bundle › Histone Acetyltransferase; Chain A › Bromodomain-like | 0.59 | 50.0 | 4.35e-01 | 92.2% | 68.1% |
| 3pe0A01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.59 | 52.0 | 4.77e-01 | 97.4% | 93.1% |
| 2pftA00 | 1.20.1280.170 | Mainly Alpha › Up-down Bundle › Monooxygenase › Exocyst complex component Exo70 | 0.59 | 51.0 | 3.16e-01 | 100.0% | 37.0% |
| 8ek4A01 | 1.20.120.20 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein | 0.59 | 48.0 | 4.03e-01 | 89.6% | 80.5% |
| 3qwwA03 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.59 | 53.0 | 3.91e-01 | 98.7% | 78.5% |
| 3fb2A01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.58 | 50.0 | 4.59e-01 | 97.4% | 90.5% |
| 4nuuB02 | 1.20.58.830 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.58 | 52.0 | 4.47e-01 | 100.0% | 92.7% |
| 3lbxB01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.57 | 50.0 | 4.52e-01 | 100.0% | 90.7% |
| 1cunA01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.56 | 49.0 | 4.48e-01 | 97.4% | 94.1% |
| 1m62A00 | 1.20.58.120 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain | 0.56 | 49.0 | 4.72e-01 | 98.7% | 87.4% |
| 4id0A02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.56 | 49.0 | 4.40e-01 | 100.0% | 82.1% |
| 3jsbA01 | 1.20.1440.300 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › RNA-directed RNA polymerase L, helical domain | 0.55 | 38.0 | 3.83e-01 | 89.6% | 70.4% |
| 1np7A02 | 1.25.40.80 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.53 | 42.0 | 3.65e-01 | 90.9% | 55.5% |
| 1rq0A01 | 6.10.140.160 | Special › Helix non-globular › Helix Hairpins › | 0.52 | 39.0 | 3.86e-01 | 81.8% | 92.8% |
| 5mq1A00 | 1.20.920.10 | Mainly Alpha › Up-down Bundle › Histone Acetyltransferase; Chain A › Bromodomain-like | 0.52 | 40.0 | 3.71e-01 | 96.1% | 63.9% |
| 7xpzA01 | 1.20.1720.10 | Mainly Alpha › Up-down Bundle › Multidrug resistance protein D › Multidrug resistance protein D | 0.51 | 46.0 | 2.90e-01 | 100.0% | 90.1% |
| 5g05P02 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.50 | 43.0 | 3.20e-01 | 96.1% | 40.8% |
ECOD (33)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3522050 | 109.3.1.131 ↗ | alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › INT_SG_DDX_CT_C | 0.74 | 50.0 | 5.15e-01 | 94.8% | 73.0% |
| 4970859 | 601.28.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › VPS28 C-terminal domain-like › VPS28 C-terminal domain-like | 0.74 | 55.0 | 5.04e-01 | 96.1% | 61.0% |
| 3529996 | 109.4.1.198 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_12 | 0.72 | 51.0 | 3.78e-01 | 89.6% | 30.0% |
| 3726818 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.69 | 53.0 | 4.21e-01 | 94.8% | 40.6% |
| 2765423 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.69 | 49.0 | 3.84e-01 | 90.9% | 35.4% |
| 3605710 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.68 | 58.0 | 5.93e-01 | 93.5% | 93.3% |
| 3969284 | 633.28.1.2 ↗ | alpha bundles › Bromodomain-like › Tsi6 › Tsi6 › DUF4404 | 0.65 | 49.0 | 4.88e-01 | 98.7% | 78.8% |
| 3396169 | 633.12.1.3 ↗ | alpha bundles › Bromodomain-like › Ta0600-like › Ta0600-like › PIEZO | 0.64 | 50.0 | 4.16e-01 | 93.5% | 47.1% |
| 3255703 | 310.2.1.0 ↗ | a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF | 0.64 | 56.0 | 5.03e-01 | 98.7% | 89.9% |
| 3720604 | 109.4.1.1418 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_7, TPR_12 | 0.63 | 58.0 | 3.56e-01 | 100.0% | 60.2% |
| 3939668 | 604.7.1.0 ↗ | alpha bundles › Spectrin repeat-like › Tubulin chaperone cofactor A › Tubulin chaperone cofactor A | 0.62 | 47.0 | 3.38e-01 | 80.5% | 70.0% |
| 4018207 | 310.2.1.0 ↗ | a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF | 0.61 | 54.0 | 4.25e-01 | 100.0% | 65.5% |
| 3242447 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.60 | 51.0 | 4.62e-01 | 94.8% | 90.5% |
| 3900969 | 604.1.1.1 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin | 0.60 | 53.0 | 4.64e-01 | 98.7% | 86.1% |
| 3522864 | 604.1.1.1 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin | 0.59 | 51.0 | 4.53e-01 | 94.8% | 84.5% |
| 3786282 | 603.1.1.5 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Syntaxin-6_N | 0.59 | 52.0 | 4.46e-01 | 97.4% | 80.0% |
| 3368223 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.59 | 51.0 | 3.76e-01 | 98.7% | 40.0% |
| 3570651 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.58 | 50.0 | 4.74e-01 | 97.4% | 94.7% |
| 3271444 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.58 | 51.0 | 3.53e-01 | 100.0% | 42.2% |
| 3518885 | 633.1.1.1 ↗ | alpha bundles › Bromodomain-like › Bromodomain › Bromodomain › Bromodomain | 0.57 | 47.0 | 4.58e-01 | 94.8% | 82.4% |
| 3243599 | 601.1.2.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) | 0.57 | 50.0 | 4.40e-01 | 98.7% | 86.1% |
| 3474685 | 604.1.1.1 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin | 0.57 | 49.0 | 4.33e-01 | 98.7% | 85.2% |
| 3579784 | 604.1.1.1 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin | 0.56 | 49.0 | 4.23e-01 | 98.7% | 78.4% |
| 3895625 | 604.1.1.1 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin | 0.56 | 48.0 | 4.14e-01 | 98.7% | 76.9% |
| 3773859 | 604.1.1.1 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin | 0.56 | 48.0 | 4.41e-01 | 97.4% | 90.5% |
| 3876659 | 220.1.1.0 ↗ | beta barrels › PH domain-like › PH domain-like › PH domain-like | 0.56 | 47.0 | 3.29e-01 | 93.5% | 36.0% |
| 4927391 | 6049.1.1.0 ↗ | alpha bundles › PH0832-like › PH0832-like › PH0832-like | 0.56 | 37.0 | 3.87e-01 | 92.2% | 75.7% |
| 3757581 | 604.1.1.1 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin | 0.55 | 47.0 | 4.27e-01 | 94.8% | 88.6% |
| 3559718 | 604.1.1.1 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin | 0.55 | 46.0 | 4.18e-01 | 94.8% | 83.6% |
| 3497641 | 604.1.1.1 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin | 0.55 | 47.0 | 4.38e-01 | 97.4% | 96.0% |
| 3489764 | 604.1.1.1 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin | 0.55 | 47.0 | 4.27e-01 | 97.4% | 91.4% |
| 3559937 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.53 | 45.0 | 4.14e-01 | 97.4% | 91.4% |
| 4485359 | 103.2.1.0 ↗ | alpha arrays › RuvA-C › ATP cone › ATP cone | 0.52 | 37.0 | 3.53e-01 | 98.7% | 61.1% |
D2
high
residues 112-169
Domain cluster:
rep: HC-Pro_protein__YP_006405405__Basella_rugose_mosaic_virus__373398__D110-165
D3
medium
residues 176-268_323-339
Domain cluster:
rep: HC-Pro__YP_001936179__Verbena_virus_Y__515446__D186-209_223-267_313-337
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00851.25 best | Peptidase_C6 | 67.0 | 2.20e-18 | 92.7% | 18.9% |
D4
medium
residues 269-322_340-456
Domain cluster:
rep: HC-Pro_protein__YP_006590094__Chinese_yam_necrotic_mosaic_virus__128818__D95-261
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00851.25 best | Peptidase_C6 | 208.4 | 2.90e-61 | 99.4% | 41.6% |