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CCD22092.1
Arc-VirHE580238__CCD22092.1__X__00004
Identity
- Accession:
- HE580238 ↗
- Protein ID:
- CCD22092.1 ↗
- Kingdom:
- archaea
Quality
74.6
mean pLDDT
Cluster
View cluster (8 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
medium
residues 19-169
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF01435.25 best | Peptidase_M48 | 33.8 | 4.20e-08 | 87.4% | 46.8% |
ECOD (24)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3959412 | 2498.1.1.10 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M48 | 0.76 | 49.0 | 5.39e-01 | 98.7% | 78.4% |
| 3586986 | 2498.1.1.29 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M78 | 0.70 | 35.0 | 3.71e-01 | 86.8% | 53.3% |
| 5029843 | 2498.1.1.0 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" | 0.67 | 41.0 | 4.47e-01 | 89.4% | 72.3% |
| 4941824 | 2498.1.1.10 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M48 | 0.57 | 53.0 | 4.18e-01 | 100.0% | 56.4% |
| 4937460 | 2498.1.1.0 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" | 0.57 | 39.0 | 4.58e-01 | 91.4% | 100.0% |
| 5019353 | 2498.1.1.10 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M48 | 0.56 | 52.0 | 4.52e-01 | 99.3% | 69.1% |
| 5081586 | 2498.1.1.10 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M48 | 0.54 | 51.0 | 4.09e-01 | 100.0% | 55.9% |
| 4293088 | 2498.1.1.10 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M48 | 0.53 | 50.0 | 3.99e-01 | 100.0% | 57.2% |
| 4998530 | 2498.1.1.10 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M48 | 0.53 | 50.0 | 4.06e-01 | 100.0% | 64.2% |
| 4961827 | 2498.1.1.10 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M48 | 0.53 | 50.0 | 4.10e-01 | 100.0% | 58.8% |
| 4987680 | 2498.1.1.10 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M48 | 0.53 | 49.0 | 3.77e-01 | 99.3% | 45.8% |
| 4436115 | 2498.1.1.10 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M48 | 0.53 | 50.0 | 3.97e-01 | 100.0% | 56.5% |
| 4990867 | 2498.1.1.10 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M48 | 0.53 | 49.0 | 3.97e-01 | 99.3% | 58.2% |
| 4565599 | 2498.1.1.10 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M48 | 0.53 | 49.0 | 3.87e-01 | 100.0% | 50.7% |
| 4456704 | 2498.1.1.10 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M48 | 0.53 | 49.0 | 3.87e-01 | 99.3% | 53.2% |
| 4984419 | 2498.1.1.10 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M48 | 0.52 | 49.0 | 4.09e-01 | 99.3% | 63.3% |
| 4983855 | 2498.1.1.10 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M48 | 0.52 | 48.0 | 4.29e-01 | 98.7% | 70.8% |
| 4958485 | 2498.1.1.10 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M48 | 0.52 | 49.0 | 3.94e-01 | 100.0% | 55.4% |
| 5042887 | 2498.1.1.10 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M48 | 0.52 | 48.0 | 3.97e-01 | 99.3% | 57.7% |
| 4971388 | 2498.1.1.0 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" | 0.52 | 46.0 | 3.73e-01 | 94.0% | 95.3% |
| 5032196 | 2498.1.1.0 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" | 0.52 | 46.0 | 3.71e-01 | 93.4% | 94.9% |
| 4943050 | 2498.1.1.10 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M48 | 0.52 | 48.0 | 3.78e-01 | 99.3% | 56.0% |
| 5053222 | 2498.1.1.10 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M48 | 0.51 | 47.0 | 3.82e-01 | 100.0% | 70.4% |
| 5072135 | 2498.1.1.10 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M48 | 0.51 | 42.0 | 3.79e-01 | 88.7% | 66.2% |
D2
medium
residues 170-235
Domain cluster:
representative
CATH (25)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4ebjA02 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.68 | 48.0 | 3.83e-01 | 74.2% | 78.5% |
| 6qs7C01 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.67 | 40.0 | 3.24e-01 | 72.7% | 30.3% |
| 2d2sA01 | 1.20.58.1210 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Exo84p, N-terminal helical domain | 0.66 | 48.0 | 4.04e-01 | 89.4% | 44.8% |
| 3l8kA01 | 3.50.50.60 | Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain | 0.63 | 38.0 | 2.69e-01 | 74.2% | 18.4% |
| 6s8bA01 | 1.10.520.30 | Mainly Alpha › Orthogonal Bundle › Peroxidase; domain 1 › AF1862-like domain | 0.61 | 51.0 | 4.05e-01 | 97.0% | 100.0% |
| 1txuA01 | 1.10.246.120 | Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › | 0.61 | 52.0 | 4.74e-01 | 100.0% | 73.4% |
| 2lm9A00 | 1.20.58.970 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.61 | 56.0 | 4.86e-01 | 100.0% | 93.8% |
| 2e52B01 | 3.40.91.70 | Alpha Beta › 3-Layer(aba) Sandwich › Restriction Endonuclease › Type II restriction endonuclease, HindIII | 0.61 | 48.0 | 3.41e-01 | 100.0% | 26.8% |
| 3kfwX03 | 1.20.58.1460 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.59 | 48.0 | 4.56e-01 | 89.4% | 76.3% |
| 6ofsA02 | 3.30.830.10 | Alpha Beta › 2-Layer Sandwich › Cytochrome Bc1 Complex; Chain A, domain 1 › Metalloenzyme, LuxS/M16 peptidase-like | 0.58 | 47.0 | 3.41e-01 | 97.0% | 67.6% |
| 2yfaA02 | 1.20.1440.210 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › | 0.58 | 48.0 | 4.04e-01 | 93.9% | 93.1% |
| 2qupA00 | 1.20.120.490 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hypothetical protein TM1646-like domain | 0.58 | 41.0 | 3.40e-01 | 75.8% | 42.0% |
| 2cwoA01 | 1.20.58.1200 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › RNA silencing suppressor P21, N-terminal domain | 0.58 | 46.0 | 4.46e-01 | 89.4% | 85.1% |
| 1dc1A02 | 1.10.238.90 | Mainly Alpha › Orthogonal Bundle › Recoverin; domain 1 › Restriction endonuclease BsobI, helical domain | 0.56 | 41.0 | 3.76e-01 | 78.8% | 93.2% |
| 1cp9A01 | 1.10.439.10 | Mainly Alpha › Orthogonal Bundle › Penicillin Amidohydrolase; domain 1 › Penicillin Amidohydrolase, domain 1 | 0.55 | 47.0 | 3.74e-01 | 98.5% | 57.5% |
| 1w5sA01 | 1.10.8.60 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › | 0.55 | 37.0 | 3.42e-01 | 80.3% | 53.4% |
| 3qqaA02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.54 | 47.0 | 3.75e-01 | 100.0% | 58.2% |
| 1i36A02 | 1.10.1040.10 | Mainly Alpha › Orthogonal Bundle › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 | 0.54 | 47.0 | 4.16e-01 | 100.0% | 93.9% |
| 5mi7A03 | 1.20.58.460 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Hyaluronidase post-catalytic domain-like | 0.53 | 45.0 | 3.10e-01 | 100.0% | 50.4% |
| 2z16B01 | 1.20.91.10 | Mainly Alpha › Up-down Bundle › Influenza Virus Matrix Protein; Chain A, domain 1 › Influenza matrix M1, N-terminal subdomain 1 | 0.53 | 45.0 | 4.28e-01 | 95.5% | 79.5% |
| 2aplA01 | 1.10.8.330 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › PG0816-like | 0.52 | 37.0 | 3.74e-01 | 75.8% | 76.5% |
| 1ax8A00 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.52 | 43.0 | 3.51e-01 | 95.5% | 47.7% |
| 3qatA01 | 3.40.366.10 | Alpha Beta › 3-Layer(aba) Sandwich › Malonyl-Coenzyme A Acyl Carrier Protein; domain 2 › Malonyl-Coenzyme A Acyl Carrier Protein, domain 2 | 0.51 | 41.0 | 2.85e-01 | 89.4% | 82.6% |
| 1z3xA01 | 1.25.40.620 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.51 | 40.0 | 3.13e-01 | 89.4% | 67.5% |
| 4bf9A02 | 1.20.225.30 | Mainly Alpha › Up-down Bundle › Bacteriocin As-48; Chain A › Dihydrouridine synthase, C-terminal recognition domain | 0.50 | 39.0 | 3.87e-01 | 98.5% | 83.6% |
ECOD (24)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1680005 | 604.30.1.1 ↗ | alpha bundles › Spectrin repeat-like › Gamma-secretase subunit PEN-2 › Gamma-secretase subunit PEN-2 › PEN-2 | 0.69 | 50.0 | 4.38e-01 | 89.4% | 51.0% |
| 5041648 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.66 | 59.0 | 4.22e-01 | 100.0% | 35.8% |
| 4944364 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.65 | 59.0 | 4.01e-01 | 100.0% | 33.8% |
| 5073730 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.65 | 58.0 | 4.16e-01 | 100.0% | 41.1% |
| 3285813 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.65 | 57.0 | 4.04e-01 | 100.0% | 33.7% |
| 5013317 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.64 | 57.0 | 4.12e-01 | 100.0% | 36.0% |
| 3696174 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.64 | 55.0 | 4.38e-01 | 100.0% | 51.4% |
| 3958664 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.63 | 55.0 | 4.21e-01 | 100.0% | 43.2% |
| 5038703 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.62 | 53.0 | 3.87e-01 | 100.0% | 37.0% |
| 3972403 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.62 | 53.0 | 3.87e-01 | 100.0% | 36.0% |
| 5045259 | 5050.1.1.14 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › ATG22 | 0.62 | 54.0 | 3.88e-01 | 100.0% | 34.0% |
| 4977940 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.61 | 53.0 | 3.82e-01 | 100.0% | 34.0% |
| 4565029 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.60 | 53.0 | 3.76e-01 | 100.0% | 33.8% |
| 4023291 | 632.7.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain | 0.60 | 42.0 | 3.68e-01 | 74.2% | 61.0% |
| 3470112 | 610.2.1.1 ↗ | alpha arrays › ERP29 C domain-like › Helical domain of Sec23/24 › Helical domain of Sec23/24 › Sec23_helical | 0.59 | 51.0 | 4.40e-01 | 100.0% | 75.5% |
| 5035526 | 604.39.1.5 ↗ | alpha bundles › Spectrin repeat-like › S-component of energy-coupling factor (ECF) transporters › S-component of energy-coupling factor (ECF) transporters › ECF_trnsprt | 0.58 | 49.0 | 3.60e-01 | 100.0% | 34.9% |
| 3522803 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.55 | 45.0 | 3.20e-01 | 90.9% | 38.6% |
| 3635468 | 604.30.1.0 ↗ | alpha bundles › Spectrin repeat-like › Gamma-secretase subunit PEN-2 › Gamma-secretase subunit PEN-2 | 0.55 | 45.0 | 4.27e-01 | 100.0% | 76.5% |
| 3186154 | 622.1.1.7 ↗ | alpha bundles › YvfG-like › HSC20 (HSCB), C-terminal oligomerisation domain › HSC20 (HSCB), C-terminal oligomerisation domain › DUF7607 | 0.54 | 44.0 | 3.87e-01 | 98.5% | 83.6% |
| 3202558 | 610.2.1.1 ↗ | alpha arrays › ERP29 C domain-like › Helical domain of Sec23/24 › Helical domain of Sec23/24 › Sec23_helical | 0.53 | 44.0 | 3.94e-01 | 100.0% | 73.3% |
| 4501358 | 206.1.1.32 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › LepB_N | 0.53 | 42.0 | 2.87e-01 | 95.5% | 42.6% |
| 3598656 | 632.22.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats | 0.53 | 40.0 | 3.61e-01 | 90.9% | 57.9% |
| 3957878 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.53 | 43.0 | 3.57e-01 | 100.0% | 62.1% |
| 4239374 | 4156.1.1.4 ↗ | alpha arrays › Sec63 N-terminal subdomain-like › Sec63 N-terminal subdomain-like › Sec63 N-terminal subdomain-like › HA2_C | 0.51 | 39.0 | 3.06e-01 | 86.4% | 72.9% |