←Back to structures

HE65

Euk-Vir

Mamestra_configurata_nucleopolyhedrovirus_A

HE65__NP_613115__Mamestra_configurata_nucleopolyhedrovirus_A__207830

Identity

Accession:
NP_613115 ↗
Protein ID:
HE65
Kingdom:
euk

Quality

75.7 mean pLDDT

Taxonomy

Naldaviricetes› Lefavirales› Baculoviridae› Alphabaculovirus› Mamestra_configurata_nucleopolyhedrovirus_A

TaxID: 207830

Cluster

View cluster (8 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 476-557
PDB
Domain cluster: rep: unknown_similar_to_AMEV019__YP_008003802__Mythimna_separata_entomopoxvirus_L__1293572__D449-527
D2 medium residues 1-107_235-263
PDB
Domain cluster: rep: LR881104.1__CAD5236280.1__LLCLJKAH_00291__00291__D3-121_248-259
D3 medium residues 108-128_141-234
PDB
Domain cluster: representative
CATH (42)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4jgiA01 1.10.1240.10 Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › Methionine synthase domain 0.73 32.0 3.86e-01 98.3% 60.0%
3nbxX03 1.20.58.1510 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.71 33.0 3.54e-01 100.0% 49.5%
2q00B00 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.69 62.0 6.07e-01 95.7% 100.0%
3o10C00 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.68 59.0 5.57e-01 93.9% 99.3%
3l1nA02 1.20.1280.140 Mainly Alpha › Up-down Bundle › Monooxygenase › 0.67 30.0 3.40e-01 100.0% 54.0%
1tqgA00 1.20.120.160 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain 0.67 53.0 5.55e-01 100.0% 92.4%
6nmnA02 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.65 58.0 5.64e-01 100.0% 89.1%
1wolA00 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.64 56.0 5.50e-01 97.4% 99.2%
1i5nB00 1.20.120.160 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain 0.62 50.0 4.90e-01 98.3% 79.8%
3jrtA00 1.20.120.1060 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.62 55.0 4.89e-01 100.0% 95.2%
3am6A00 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.62 54.0 4.37e-01 97.4% 83.9%
2vwaA00 1.20.58.1330 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Plasmodium falciparum UIS3 membrane protein 0.61 32.0 3.49e-01 100.0% 58.6%
3buxB01 1.20.930.20 Mainly Alpha › Up-down Bundle › Transcription Elongation Factor S-II; Chain A › Adaptor protein Cbl, N-terminal domain 0.61 45.0 4.39e-01 87.0% 69.8%
7c4sB01 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.60 53.0 4.09e-01 100.0% 79.7%
4hr1A00 1.20.1270.410 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.60 45.0 4.51e-01 78.3% 87.3%
2wbiB03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.59 46.0 4.13e-01 81.7% 73.4%
1b0bA00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.58 38.0 3.59e-01 99.1% 53.9%
6t0bc02 1.20.120.80 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c oxidase, subunit III, four-helix bundle 0.58 51.0 4.37e-01 99.1% 68.6%
4o6yB00 1.20.120.1770 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.57 50.0 4.21e-01 100.0% 71.1%
1x8zB00 1.20.140.40 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Invertase/pectin methylesterase inhibitor family protein 0.57 42.0 3.93e-01 78.3% 66.7%
2b5dX02 1.20.1430.10 Mainly Alpha › Up-down Bundle › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase, middle domain 0.57 37.0 3.77e-01 70.4% 66.7%
5tcsA01 1.10.418.30 Mainly Alpha › Orthogonal Bundle › Actin-binding Protein, T-fimbrin; domain 1 › Ncd80 complex, Ncd80 subunit 0.56 43.0 4.38e-01 88.7% 84.4%
1yo7A00 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.56 42.0 4.18e-01 79.1% 77.5%
3p5nA00 1.10.1760.20 Mainly Alpha › Orthogonal Bundle › Arp2/3 complex 21 kDa subunit ARPC3 › 0.56 40.0 3.58e-01 78.3% 51.2%
3zh9B03 1.20.272.10 Mainly Alpha › Up-down Bundle › Zinc Finger, Delta Prime; domain 3 › 0.56 43.0 4.22e-01 82.6% 97.6%
6jpaE00 1.20.140.150 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › 0.55 42.0 3.77e-01 81.7% 73.4%
5dqqA01 1.20.120.350 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Voltage-gated potassium channels. Chain C 0.55 48.0 4.69e-01 99.1% 87.5%
3hiuD00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.55 41.0 3.75e-01 78.3% 96.1%
1e3mB04 1.10.1420.10 Mainly Alpha › Orthogonal Bundle › MutS, DNA mismatch repair protein; Chain A, domain 3 › 0.55 49.0 4.49e-01 100.0% 85.5%
5x56B00 1.20.58.810 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Photosystem II Pbs27 0.55 45.0 4.72e-01 99.1% 100.0%
2b0hA01 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.54 48.0 4.69e-01 100.0% 95.3%
1h6gA02 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.54 46.0 4.58e-01 95.7% 100.0%
2gscC00 1.20.1440.60 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 23S rRNA-intervening sequence 0.54 37.0 3.84e-01 75.7% 73.6%
4dwlA00 1.20.1440.60 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 23S rRNA-intervening sequence 0.53 37.0 3.79e-01 79.1% 75.0%
3rx6A00 1.20.58.1090 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phage polarity suppression protein monomer 0.53 39.0 3.31e-01 76.5% 90.9%
3kp9A01 1.20.1440.130 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › VKOR domain 0.53 39.0 3.53e-01 78.3% 67.3%
1u7lA02 1.20.1460.10 Mainly Alpha › Up-down Bundle › subunit c (vma5p) of the yeast v-atpase, domain 2 › subunit c (vma5p) of the yeast v-atpase, domain 2 0.52 39.0 3.37e-01 79.1% 52.5%
1st6A01 1.20.120.810 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Vinculin, Vh2 four-helix bundle 0.52 46.0 3.61e-01 100.0% 67.8%
1q16C01 1.20.950.20 Mainly Alpha › Up-down Bundle › Fumarate Reductase Cytochrome B subunit › Transmembrane di-heme cytochromes, Chain C 0.52 45.0 3.72e-01 97.4% 73.4%
6mgiA03 1.20.1440.90 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › Phosphoenolpyruvate/pyruvate domain 0.51 37.0 3.53e-01 76.5% 83.9%
1jm6B02 1.20.140.20 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Alpha-ketoacid/pyruvate dehydrogenase kinase, N-terminal domain 0.51 41.0 3.75e-01 87.8% 74.5%
6j5tB02 1.10.510.10 Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 0.51 40.0 3.47e-01 86.1% 96.2%
ECOD (46)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4406945 601.7.1.0 ↗ alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain 0.72 66.0 6.52e-01 100.0% 94.2%
5014864 601.7.1.0 ↗ alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain 0.71 58.0 6.04e-01 92.2% 96.2%
54497 601.7.1.0 ↗ alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain 0.65 58.0 5.67e-01 100.0% 88.3%
4977057 3960.1.1.0 ↗ alpha arrays › Aminoglycoside adenyltransferase AadA C-terminal domain › Aminoglycoside adenyltransferase AadA C-terminal domain › Aminoglycoside adenyltransferase AadA C-terminal domain 0.65 56.0 5.60e-01 96.5% 93.0%
5001173 601.7.1.1 ↗ alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain › HepT-like 0.63 54.0 5.27e-01 95.7% 100.0%
3725616 601.1.1.0 ↗ alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.63 55.0 4.94e-01 96.5% 100.0%
3275208 5001.1.1.5 ↗ alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_3 0.62 55.0 4.39e-01 99.1% 81.2%
3591754 192.29.1.0 ↗ alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.62 52.0 4.93e-01 92.2% 88.6%
3700267 601.39.1.0 ↗ alpha bundles › Four-helical up-and-down bundle › Enhancer of filamentation 1 › Enhancer of filamentation 1 0.62 53.0 4.91e-01 93.0% 96.6%
3464696 192.29.1.0 ↗ alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.61 55.0 5.33e-01 100.0% 98.5%
3735275 192.29.1.0 ↗ alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.61 54.0 4.68e-01 99.1% 92.2%
3222373 605.4.1.18 ↗ alpha duplicates or obligate multimers › ROP-like › ROP protein › ROP protein › PF29357 0.60 43.0 4.84e-01 75.7% 100.0%
3557371 3871.1.1.0 ↗ alpha duplicates or obligate multimers › PHIST › PHIST › PHIST 0.60 55.0 5.07e-01 100.0% 89.0%
3255852 616.1.1.0 ↗ alpha arrays › S15/NS1 RNA-binding domain › S15/NS1 RNA-binding domain › S15/NS1 RNA-binding domain 0.59 34.0 3.21e-01 95.7% 47.1%
5064355 310.2.1.0 ↗ a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF 0.59 35.0 3.93e-01 70.4% 75.6%
3725612 632.1.1.0 ↗ alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain 0.59 46.0 4.17e-01 81.7% 80.0%
4944283 192.29.1.0 ↗ alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.58 50.0 4.79e-01 99.1% 94.3%
3230066 3684.1.1.0 ↗ alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like 0.58 52.0 4.87e-01 100.0% 92.1%
5014336 192.29.1.0 ↗ alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.58 52.0 4.81e-01 100.0% 90.3%
3732719 601.1.1.25 ↗ alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › GIT1_C 0.58 52.0 4.92e-01 99.1% 93.3%
3328692 7015.1.1.0 ↗ alpha bundles › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain 0.57 43.0 4.07e-01 81.7% 77.2%
3584217 632.7.1.0 ↗ alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain 0.57 40.0 4.04e-01 73.0% 81.7%
4953536 5073.1.2.0 ↗ alpha bundles › Calcium ATPase transmembrane domain-related › Calcium ATPase transmembrane domain-related › Copper efflux ATPase transmembrane domain 0.56 44.0 3.56e-01 97.4% 42.5%
3651030 633.4.1.1 ↗ alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI 0.56 44.0 3.87e-01 84.3% 70.3%
3221738 192.29.1.172 ↗ alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › PF29678 0.56 47.0 4.47e-01 94.8% 86.4%
3523264 633.23.1.22 ↗ alpha bundles › Bromodomain-like › Claudin › Claudin › MARVEL 0.55 41.0 3.93e-01 76.5% 72.3%
3944997 3236.1.1.3 ↗ alpha complex topology › Cation-proton antiporter › Cation-proton antiporter (CPA) › Cation-proton antiporter (CPA) › Mem_trans 0.55 49.0 3.66e-01 100.0% 64.9%
4879693 5054.1.1.0 ↗ alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels 0.55 49.0 4.69e-01 100.0% 86.9%
3230759 192.29.1.0 ↗ alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.55 49.0 3.82e-01 100.0% 48.3%
3390092 192.29.1.0 ↗ alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.55 50.0 4.79e-01 100.0% 96.2%
3970926 3236.1.1.3 ↗ alpha complex topology › Cation-proton antiporter › Cation-proton antiporter (CPA) › Cation-proton antiporter (CPA) › Mem_trans 0.55 48.0 3.63e-01 100.0% 66.3%
3867721 5001.1.1.5 ↗ alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_3 0.55 47.0 3.79e-01 100.0% 77.2%
3974312 5050.1.1.9 ↗ alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.54 47.0 4.01e-01 98.3% 65.6%
3492595 192.29.1.11 ↗ alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › FerA 0.54 48.0 4.71e-01 100.0% 94.4%
54292 633.10.1.0 ↗ alpha bundles › Bromodomain-like › IVS-encoded protein-like › IVS-encoded protein-like 0.53 41.0 4.11e-01 80.9% 80.9%
54287 633.10.1.0 ↗ alpha bundles › Bromodomain-like › IVS-encoded protein-like › IVS-encoded protein-like 0.53 38.0 3.89e-01 75.7% 74.8%
5078867 603.1.1.0 ↗ alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.53 34.0 3.79e-01 91.3% 83.3%
3563976 601.4.1.79 ↗ alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains › 4HB_KIF14 0.53 46.0 4.14e-01 97.4% 84.4%
4026169 5050.1.1.28 ↗ alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › BT1 0.52 46.0 3.94e-01 100.0% 67.9%
4982818 601.30.1.1 ↗ alpha bundles › Four-helical up-and-down bundle › Helical bundle domain in hypothetical protein PH1320 › Helical bundle domain in hypothetical protein PH1320 › NOG1_N 0.52 44.0 4.40e-01 93.9% 97.5%
3364448 5050.1.1.28 ↗ alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › BT1 0.52 45.0 3.78e-01 99.1% 63.8%
3964875 4953.1.1.0 ↗ beta barrels › L-aspartase C-terminal domain-like › L-aspartase C-terminal domain-like › L-aspartase C-terminal domain-like 0.52 37.0 3.58e-01 74.8% 88.1%
3167982 109.4.1.1677 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › HAT_Syf1_M, HAT_Syf1_CNRKL1_N 0.52 37.0 2.61e-01 74.8% 57.1%
3613499 601.4.1.0 ↗ alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains 0.51 45.0 4.07e-01 100.0% 77.0%
4023423 5057.1.1.0 ↗ alpha bundles › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore 0.50 44.0 3.85e-01 100.0% 85.0%
3286236 5050.1.1.9 ↗ alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.50 43.0 3.61e-01 100.0% 58.6%
D4 medium residues 264-294_420-473
PDB
Domain cluster: rep: he65__YP_009112583__Agrotis_segetum_nucleopolyhedrovirus_B__1580580__D258-283_404-459
D5 medium residues 295-419
PDB
Domain cluster: rep: LacPavin_0818_WC40_scaffold_26136_prodigal-single.1__X__X__00216__D38-133