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HNH-family_endonuclease

Euk-Vir

Brazilian_marseillevirus

HNH-family_endonuclease__YP_009238884__Brazilian_marseillevirus__1813599

Identity

Accession:
YP_009238884 ↗
Protein ID:
HNH-family_endonuclease
Kingdom:
euk

Quality

89.2 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 5-63
PDB
CATH (65)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3tw8A01 3.30.450.200 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › Longin module 0.72 55.0 4.21e-01 83.1% 37.0%
2ywqA00 3.30.160.100 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Ribosome hibernation promotion factor-like 0.72 59.0 5.19e-01 91.5% 75.0%
2k7iA01 3.30.160.160 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › YegP-like 0.71 52.0 5.61e-01 79.7% 95.8%
2dixA01 3.30.160.20 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › 0.70 60.0 5.50e-01 96.6% 92.3%
4htgA03 3.30.160.40 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Porphobilinogen deaminase, C-terminal domain 0.70 52.0 4.83e-01 83.1% 82.3%
2aehA03 2.30.29.30 Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 0.69 52.0 4.23e-01 81.4% 43.2%
1l3aA00 2.30.31.10 Mainly Beta › Roll › Transcriptional Co-activator pc4; Chain A › Transcriptional Coactivator Pc4; Chain A 0.66 47.0 3.40e-01 74.6% 72.3%
1h4rA03 2.30.29.30 Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 0.65 40.0 3.56e-01 71.2% 39.6%
1olzA01 2.130.10.10 Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › YVTN repeat-like/Quinoprotein amine dehydrogenase 0.65 48.0 2.84e-01 79.7% 46.3%
2nugB02 3.30.160.20 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › 0.65 53.0 5.05e-01 93.2% 98.6%
7r97A02 3.30.160.20 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › 0.65 50.0 4.89e-01 88.1% 100.0%
3k44B00 3.30.2450.30 Alpha Beta › 2-Layer Sandwich › Secreted effector protein pipB2 fold › 0.65 51.0 3.88e-01 86.4% 82.1%
2lezA00 3.30.2450.10 Alpha Beta › 2-Layer Sandwich › Secreted effector protein pipB2 fold › Secreted effector protein pipB2 0.64 48.0 3.86e-01 81.4% 64.2%
2l2mA00 3.30.160.20 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › 0.64 52.0 5.03e-01 94.9% 97.1%
3nvqA01 2.130.10.10 Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › YVTN repeat-like/Quinoprotein amine dehydrogenase 0.63 47.0 2.83e-01 81.4% 45.4%
1dfvA00 2.40.128.20 Mainly Beta › Beta Barrel › Lipocalin › Calycin beta-barrel core domain 0.63 43.0 3.14e-01 72.9% 59.0%
1di2A00 3.30.160.20 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › 0.63 50.0 4.81e-01 91.5% 100.0%
6pxcA00 3.30.505.10 Alpha Beta › 2-Layer Sandwich › SHC Adaptor Protein › SH2 domain 0.62 51.0 4.33e-01 94.9% 90.4%
3ebwA01 2.40.128.20 Mainly Beta › Beta Barrel › Lipocalin › Calycin beta-barrel core domain 0.62 46.0 3.49e-01 79.7% 59.2%
1d5aA01 3.30.342.10 Alpha Beta › 2-Layer Sandwich › DNA Polymerase; Chain A, domain 1 › DNA Polymerase, chain B, domain 1 0.62 45.0 3.37e-01 78.0% 86.1%
2lg1A02 2.30.29.30 Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 0.61 43.0 3.55e-01 81.4% 39.1%
3qwmA00 2.30.29.30 Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 0.61 46.0 3.60e-01 81.4% 82.7%
3jtzA00 3.30.160.390 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Integrase, DNA-binding domain 0.61 49.0 4.61e-01 93.2% 90.9%
2lmcB00 2.40.50.100 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › RNA polymerase II/Efflux pump adaptor protein, barrel-sandwich hybrid domain 0.61 44.0 4.45e-01 83.1% 77.0%
3lxrF00 1.10.4120.20 Mainly Alpha › Orthogonal Bundle › SopE-like GEF fold › 0.60 45.0 3.21e-01 81.4% 78.5%
3sreA00 2.120.10.30 Mainly Beta › 6 Propeller › Neuraminidase › TolB, C-terminal domain 0.60 42.0 2.69e-01 76.3% 29.2%
1a15A00 2.40.50.40 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › 0.60 39.0 3.78e-01 71.2% 58.2%
3m9qA01 2.30.30.140 Mainly Beta › Roll › SH3 type barrels. › 0.60 45.0 4.24e-01 81.4% 90.3%
2dmyA00 3.30.160.20 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › 0.59 49.0 4.20e-01 93.2% 75.3%
2h1eA02 2.40.50.40 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › 0.59 43.0 4.47e-01 78.0% 89.1%
3f6gA01 3.30.160.740 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › 0.59 43.0 4.35e-01 81.4% 96.6%
4chjA00 2.30.29.30 Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 0.58 49.0 3.86e-01 93.2% 87.1%
1z9fA00 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.58 42.0 3.76e-01 79.7% 85.4%
3ulbA01 2.30.29.30 Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 0.58 42.0 3.79e-01 78.0% 81.9%
1g5hA01 3.30.930.10 Alpha Beta › 2-Layer Sandwich › BirA Bifunctional Protein; domain 2 › Bira Bifunctional Protein; Domain 2 0.58 47.0 3.12e-01 98.3% 78.9%
4f0qA02 3.40.1350.10 Alpha Beta › 3-Layer(aba) Sandwich › Trna Endonuclease; Chain: A, domain 1 › 0.57 40.0 2.89e-01 76.3% 51.0%
3ewaA02 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.57 40.0 2.68e-01 74.6% 94.4%
1c9rA04 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.57 42.0 3.56e-01 83.1% 49.5%
3a5zB01 2.30.30.30 Mainly Beta › Roll › SH3 type barrels. › 0.57 45.0 4.42e-01 89.8% 100.0%
1wv4B00 2.30.110.10 Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A 0.57 40.0 3.05e-01 74.6% 72.1%
4dy0B02 2.30.39.10 Mainly Beta › Roll › Alpha-1-antitrypsin; domain 1 › Alpha-1-antitrypsin, domain 1 0.57 47.0 3.74e-01 94.9% 82.0%
2cqaA01 2.40.50.360 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › RuvBL1 DNA/RNA binding domain 0.57 43.0 4.02e-01 83.1% 91.9%
1ci0B00 2.30.110.10 Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A 0.57 39.0 2.78e-01 74.6% 79.9%
1rypC00 3.60.20.10 Alpha Beta › 4-Layer Sandwich › Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1 › Aminohydrolase, N-terminal nucleophile (Ntn) domain 0.57 44.0 2.95e-01 86.4% 57.4%
3a57A00 2.60.270.30 Mainly Beta › Sandwich › Mutm (Fpg) Protein; Chain: A, domain 2 › Vibrio parahaemolyticus thermostable direct hemolysin 0.56 42.0 3.25e-01 83.1% 50.0%
6u7jA02 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.56 42.0 3.69e-01 81.4% 87.6%
5wceA02 3.10.150.10 Alpha Beta › Roll › DNA Polymerase III; Chain A, domain 2 › DNA Polymerase III, subunit A, domain 2 0.56 41.0 3.25e-01 79.7% 41.9%
4p78C00 3.30.920.30 Alpha Beta › 2-Layer Sandwich › Metal Transport, Frataxin; Chain A › Hypothetical protein. 0.56 42.0 4.18e-01 88.1% 83.3%
1nqzA00 3.90.79.10 Alpha Beta › Alpha-Beta Complex › Nucleoside Triphosphate Pyrophosphohydrolase › Nucleoside Triphosphate Pyrophosphohydrolase 0.55 41.0 2.99e-01 86.4% 27.5%
6mzoA01 3.40.50.11970 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.55 41.0 3.32e-01 83.1% 77.8%
3f2bA01 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.55 40.0 3.54e-01 81.4% 80.2%
5b4wA00 2.130.10.10 Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › YVTN repeat-like/Quinoprotein amine dehydrogenase 0.55 48.0 2.89e-01 100.0% 26.3%
2l33A00 3.30.160.20 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › 0.54 43.0 3.93e-01 98.3% 72.5%
2giaA00 2.30.31.40 Mainly Beta › Roll › Transcriptional Co-activator pc4; Chain A › 0.54 37.0 2.94e-01 76.3% 63.6%
1uhzA00 3.30.160.20 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › 0.54 43.0 3.88e-01 93.2% 82.0%
3l4gC04 3.30.930.10 Alpha Beta › 2-Layer Sandwich › BirA Bifunctional Protein; domain 2 › Bira Bifunctional Protein; Domain 2 0.54 42.0 2.91e-01 98.3% 88.3%
4chmB00 2.30.29.30 Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 0.54 43.0 3.46e-01 91.5% 93.5%
1uebA01 2.30.30.30 Mainly Beta › Roll › SH3 type barrels. › 0.54 43.0 4.27e-01 91.5% 100.0%
5c0pA00 2.115.10.20 Mainly Beta › 5 Propeller › Tachylectin-2; Chain A › Glycosyl hydrolase domain; family 43 0.53 43.0 2.91e-01 100.0% 90.5%
2pmaA01 2.40.70.10 Mainly Beta › Beta Barrel › Cathepsin D, subunit A; domain 1 › Acid Proteases 0.53 42.0 3.51e-01 96.6% 82.6%
3dcxA00 2.30.29.50 Mainly Beta › Roll › PH-domain like › Bacterial Pleckstrin homology domain 0.52 37.0 3.16e-01 81.4% 40.2%
3fyfA00 2.40.128.410 Mainly Beta › Beta Barrel › Lipocalin › 0.52 38.0 2.91e-01 79.7% 76.5%
3dghA02 3.50.50.60 Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain 0.51 37.0 3.05e-01 81.4% 100.0%
1t6aA02 3.30.310.120 Alpha Beta › 2-Layer Sandwich › TATA-Binding Protein › Rbstp2229 like protein 0.51 37.0 3.44e-01 79.7% 69.2%
1fhoA00 2.30.29.30 Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 0.51 37.0 3.09e-01 83.1% 87.4%
ECOD (70)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4026643 330.1.1.0 a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like 0.75 61.0 5.48e-01 91.5% 81.2%
3659202 1.1.11.0 beta barrels › cradle loop barrel › RIFT-related › Type II restriction endonuclease effector domain 0.74 47.0 4.23e-01 72.9% 47.5%
4188237 4325.1.1.1 mixed a+b and a/b › YegP-like › YegP-like › YegP-like › DUF1508 0.74 56.0 5.83e-01 81.4% 87.3%
3551723 223.2.1.4 a+b three layers › Profilin-like › profilin-like › profilin-like › DENN,uDENN 0.73 56.0 4.08e-01 83.1% 31.9%
3591940 223.2.1.19 a+b three layers › Profilin-like › profilin-like › profilin-like › Intu_longin_1 0.71 53.0 3.69e-01 83.1% 24.7%
3505384 5.1.4.0 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed 0.70 49.0 3.07e-01 74.6% 23.7%
4360067 896.1.1.1 a+b two layers › SRP9/14-like › Signal recognition particle alu RNA binding heterodimer SRP9/14-related › Signal recognition particle alu RNA binding heterodimer SRP9/14-related › Ribosomal_L38e 0.70 52.0 4.70e-01 79.7% 62.0%
3584575 220.1.1.1 beta barrels › PH domain-like › PH domain-like › PH domain-like › PH 0.68 49.0 3.54e-01 83.1% 27.1%
5080919 220.1.1.0 beta barrels › PH domain-like › PH domain-like › PH domain-like 0.67 48.0 4.01e-01 81.4% 42.9%
3327993 5.1.4.156 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › Ge1_WD40 0.67 49.0 3.09e-01 78.0% 30.0%
4115704 330.4.1.1 a+b two layers › dsRBD-like › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobil_deamC 0.67 53.0 5.03e-01 91.5% 84.0%
3927637 10.1.1.17 beta sandwiches › jelly-roll › Concanavalin A-like › Concanavalin A-like lectins/glucanases › Laminin_G_2 0.67 48.0 3.32e-01 76.3% 61.0%
3291683 4221.1.1.0 a+b two layers › YkuJ-like › YkuJ-like › YkuJ-like 0.66 55.0 4.84e-01 94.9% 82.2%
3385523 2.1.1.0 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein 0.66 50.0 4.03e-01 79.7% 66.4%
3940690 375.1.1.0 few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related 0.66 46.0 3.79e-01 72.9% 87.6%
3900115 220.1.1.1 beta barrels › PH domain-like › PH domain-like › PH domain-like › PH 0.66 49.0 3.80e-01 81.4% 36.2%
4023893 220.1.1.1 beta barrels › PH domain-like › PH domain-like › PH domain-like › PH 0.66 49.0 4.04e-01 79.7% 43.6%
3508601 220.1.1.47 beta barrels › PH domain-like › PH domain-like › PH domain-like › PH_16 0.66 50.0 3.52e-01 83.1% 54.7%
4973114 218.1.1.0 a+b two layers › Enolase-N/ribosomal protein › Enolase N-terminal domain-like › Enolase N-terminal domain-like 0.66 49.0 4.29e-01 83.1% 55.8%
4479389 2.1.1.15 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › tRNA_anti-codon 0.66 49.0 3.91e-01 79.7% 65.2%
3964724 3675.1.1.1 a+b complex topology › DNA gyrase subunit B insertion domain › DNA gyrase subunit B insertion domain › DNA gyrase subunit B insertion domain › GyrB_insert 0.65 49.0 3.59e-01 79.7% 48.4%
4019656 220.1.1.211 beta barrels › PH domain-like › PH domain-like › PH domain-like › DUF7612 0.64 47.0 3.65e-01 79.7% 34.8%
5072644 218.1.1.2 a+b two layers › Enolase-N/ribosomal protein › Enolase N-terminal domain-like › Enolase N-terminal domain-like › Enolase_N 0.64 48.0 3.81e-01 83.1% 86.2%
401241 218.1.1.2 a+b two layers › Enolase-N/ribosomal protein › Enolase N-terminal domain-like › Enolase N-terminal domain-like › Enolase_N 0.64 47.0 3.60e-01 81.4% 49.7%
5054090 218.1.1.2 a+b two layers › Enolase-N/ribosomal protein › Enolase N-terminal domain-like › Enolase N-terminal domain-like › Enolase_N 0.64 48.0 3.86e-01 83.1% 85.8%
3649062 218.1.1.2 a+b two layers › Enolase-N/ribosomal protein › Enolase N-terminal domain-like › Enolase N-terminal domain-like › Enolase_N 0.63 48.0 3.62e-01 83.1% 86.5%
4278743 2.1.1.15 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › tRNA_anti-codon 0.63 46.0 3.82e-01 79.7% 66.4%
4099166 2.1.1.15 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › tRNA_anti-codon 0.63 46.0 3.81e-01 79.7% 66.4%
4238204 2.1.1.15 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › tRNA_anti-codon 0.63 46.0 3.86e-01 79.7% 70.5%
3781077 375.1.1.26 few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related › Rpr2 0.63 45.0 3.73e-01 76.3% 82.5%
3479661 330.1.1.0 a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like 0.63 53.0 4.45e-01 100.0% 86.4%
3605574 319.1.1.0 beta sandwiches › HSP20-like › HSP20-like chaperones › HSP20-like chaperones 0.63 47.0 3.41e-01 83.1% 37.7%
3730099 330.1.1.1 a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like › dsrm 0.62 52.0 4.90e-01 94.9% 85.1%
3990098 2.1.1.15 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › tRNA_anti-codon 0.62 47.0 3.88e-01 83.1% 75.5%
4478350 218.1.1.2 a+b two layers › Enolase-N/ribosomal protein › Enolase N-terminal domain-like › Enolase N-terminal domain-like › Enolase_N 0.62 47.0 3.81e-01 83.1% 90.8%
3288884 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.62 51.0 4.29e-01 93.2% 86.7%
3230224 708.1.1.0 beta complex topology › ETN0001 domain-like › ETN0001 domain-like › NAC/WRKY/GCM/WOPR domain 0.62 46.0 3.37e-01 81.4% 58.3%
4965392 802.1.1.0 a+b two layers › Hypothetical protein TM0160 › Hypothetical protein TM0160 › Hypothetical protein TM0160 0.62 43.0 4.54e-01 76.3% 86.0%
3282699 2.1.1.15 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › tRNA_anti-codon 0.62 45.0 3.70e-01 79.7% 63.5%
3510281 246.3.1.4 a+b four layers › Carbon-nitrogen hydrolase-like › DNase I-like › DNase I-like › Exo_endo_phos2 0.62 45.0 3.07e-01 76.3% 23.9%
4032678 2.1.1.15 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › tRNA_anti-codon 0.62 47.0 3.97e-01 83.1% 83.0%
3549045 330.1.1.1 a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like › dsrm 0.61 51.0 4.33e-01 100.0% 87.3%
3994778 220.1.1.0 beta barrels › PH domain-like › PH domain-like › PH domain-like 0.61 48.0 3.70e-01 88.1% 55.4%
5029083 2.1.1.0 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein 0.61 47.0 3.52e-01 83.1% 98.0%
3642022 218.1.1.2 a+b two layers › Enolase-N/ribosomal protein › Enolase N-terminal domain-like › Enolase N-terminal domain-like › Enolase_N 0.61 46.0 3.92e-01 83.1% 78.0%
3287903 802.1.1.1 a+b two layers › Hypothetical protein TM0160 › Hypothetical protein TM0160 › Hypothetical protein TM0160 › BFN_dom 0.61 42.0 4.49e-01 72.9% 86.0%
3466584 2.1.1.0 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein 0.60 45.0 4.43e-01 83.1% 87.7%
3387410 2.1.1.0 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein 0.60 44.0 3.60e-01 79.7% 67.8%
4032340 2.1.1.15 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › tRNA_anti-codon 0.60 44.0 3.69e-01 79.7% 69.5%
3216768 330.1.1.0 a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like 0.60 47.0 4.11e-01 96.6% 66.7%
3626785 4041.1.1.1 a+b complex topology › insertion domain in beta subunit of DNA dependent RNA-polymerase › insertion domain in beta subunit of DNA dependent RNA-polymerase › insertion domain in beta subunit of DNA dependent RNA-polymerase › RNA_pol_Rpb2_2 0.59 44.0 3.19e-01 81.4% 78.9%
3348638 330.1.1.1 a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like › dsrm 0.59 49.0 4.07e-01 98.3% 71.3%
3604446 2004.1.1.480 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N, AAA_21, AAA_29 0.59 43.0 2.51e-01 79.7% 21.1%
4477850 2.1.1.15 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › tRNA_anti-codon 0.59 44.0 3.81e-01 83.1% 81.0%
4552570 2.1.1.15 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › tRNA_anti-codon 0.59 43.0 3.63e-01 81.4% 72.7%
3172576 277.1.1.0 a+b two layers › PX domain › PX domain › PX domain 0.58 44.0 3.59e-01 84.7% 100.0%
3959920 2.1.1.15 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › tRNA_anti-codon 0.57 42.0 3.49e-01 81.4% 63.5%
None 0.57 43.0 2.63e-01 79.7% 26.8%
3961321 223.3.1.2 a+b three layers › Profilin-like › a+b domain in beta-lactamase/transpeptidase-like proteins › a+b domain in beta-lactamase/transpeptidase-like proteins › Peptidase_S11 0.57 43.0 3.73e-01 89.8% 58.2%
3231587 220.1.1.0 beta barrels › PH domain-like › PH domain-like › PH domain-like 0.57 40.0 3.58e-01 76.3% 64.4%
4188650 2.1.1.15 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › tRNA_anti-codon 0.56 42.0 3.61e-01 83.1% 75.2%
3658860 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.55 40.0 2.72e-01 78.0% 27.7%
5056920 2004.1.1.58 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Mg_chelatase 0.55 41.0 2.59e-01 79.7% 54.8%
4932479 2484.1.1.34 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 0.55 45.0 2.93e-01 96.6% 35.7%
3257362 220.1.1.1 beta barrels › PH domain-like › PH domain-like › PH domain-like › PH 0.55 41.0 3.41e-01 83.1% 86.4%
3882636 214.1.1.11 a+b two layers › SH2 › SH2 › SH2 › PF27628 0.55 44.0 3.47e-01 91.5% 76.2%
4308192 2.1.1.15 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › tRNA_anti-codon 0.55 43.0 3.25e-01 89.8% 71.6%
5018514 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.54 42.0 3.25e-01 84.7% 65.9%
4000391 206.1.1.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase 0.53 40.0 2.61e-01 83.1% 33.1%
3300719 7.1.1.0 beta barrels › PDZ domain › PDZ domain › PDZ domain 0.51 38.0 3.15e-01 86.4% 98.3%
D2 high residues 71-163
PDB
D3 high residues 177-233
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00847.27 best AP2 33.9 4.30e-08 82.5% 79.6%
CATH (37)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1k3eB02 3.30.1460.10 Alpha Beta › 2-Layer Sandwich › Yope Regulator; Chain: A, › 0.73 63.0 5.20e-01 98.2% 96.2%
2jkgA00 3.30.450.30 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › Dynein light chain 2a, cytoplasmic 0.70 53.0 3.84e-01 84.2% 30.9%
1z47A03 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.61 40.0 4.17e-01 84.2% 77.6%
1utbB01 3.40.190.10 Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › Periplasmic binding protein-like II 0.61 44.0 3.47e-01 93.0% 35.2%
2j3tD01 3.30.450.70 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › 0.61 47.0 3.66e-01 87.7% 38.8%
5mmiG01 3.90.930.12 Alpha Beta › Alpha-Beta Complex › Outer Surface Protein A; domain 3 › Ribosomal protein L6 0.60 51.0 4.52e-01 94.7% 96.4%
3j7aF03 2.30.30.30 Mainly Beta › Roll › SH3 type barrels. › 0.60 38.0 3.56e-01 96.5% 50.7%
1b9mA03 2.40.50.100 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › RNA polymerase II/Efflux pump adaptor protein, barrel-sandwich hybrid domain 0.60 41.0 3.85e-01 84.2% 54.9%
1zarA02 3.30.200.20 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 0.60 45.0 4.02e-01 80.7% 65.4%
3n89A02 3.30.310.210 Alpha Beta › 2-Layer Sandwich › TATA-Binding Protein › 0.59 46.0 3.54e-01 86.0% 51.1%
6hoxA01 2.60.120.200 Mainly Beta › Sandwich › Jelly Rolls › 0.58 50.0 3.36e-01 100.0% 44.8%
3ed3A01 3.40.30.10 Alpha Beta › 3-Layer(aba) Sandwich › Glutaredoxin › Glutaredoxin 0.57 42.0 3.41e-01 82.5% 76.9%
4eo0A00 3.30.110.160 Alpha Beta › 2-Layer Sandwich › Translation Initiation Factor IF3 › 0.57 43.0 3.52e-01 82.5% 91.5%
4mfzA02 3.40.630.120 Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › 0.56 41.0 3.10e-01 78.9% 34.0%
2pw4A00 1.10.3300.10 Mainly Alpha › Orthogonal Bundle › Jann2411-like fold › Jann2411-like domain 0.56 50.0 3.47e-01 100.0% 72.7%
3k44B00 3.30.2450.30 Alpha Beta › 2-Layer Sandwich › Secreted effector protein pipB2 fold › 0.56 42.0 3.26e-01 84.2% 75.7%
2npnA02 3.30.950.10 Alpha Beta › 2-Layer Sandwich › Methyltransferase, Cobalt-precorrin-4 Transmethylase; Domain 2 › Tetrapyrrole methylase, C-terminal domain 0.56 45.0 3.71e-01 93.0% 47.7%
1gutA00 2.40.50.100 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › RNA polymerase II/Efflux pump adaptor protein, barrel-sandwich hybrid domain 0.56 39.0 3.78e-01 84.2% 61.2%
3h7mA01 3.40.190.10 Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › Periplasmic binding protein-like II 0.55 40.0 3.16e-01 82.5% 34.3%
5mz2I00 3.30.190.10 Alpha Beta › 2-Layer Sandwich › Ribulose 1,5 Bisphosphate Carboxylase/Oxygenase › Ribulose bisphosphate carboxylase, small subunit 0.55 44.0 3.50e-01 96.5% 87.1%
2wweA01 3.30.1520.10 Alpha Beta › 2-Layer Sandwich › PX Domain › Phox-like domain 0.55 45.0 3.89e-01 100.0% 65.4%
2h7fX02 3.90.15.10 Alpha Beta › Alpha-Beta Complex › Topoisomerase I; Chain A, domain 3 › Topoisomerase I; Chain A, domain 3 0.55 46.0 3.02e-01 93.0% 94.2%
4pk9A00 3.40.1090.10 Alpha Beta › 3-Layer(aba) Sandwich › Cytosolic phospholipase A2 catalytic domain › Cytosolic phospholipase A2 catalytic domain 0.54 45.0 2.83e-01 100.0% 59.9%
4hscX04 2.60.40.1430 Mainly Beta › Sandwich › Immunoglobulin-like › Perfringolysin, domain 4 0.54 43.0 3.53e-01 89.5% 78.2%
2z3gB00 3.40.140.10 Alpha Beta › 3-Layer(aba) Sandwich › Cytidine Deaminase; domain 2 › Cytidine Deaminase, domain 2 0.54 46.0 3.64e-01 100.0% 84.3%
1v2yA00 3.10.20.90 Alpha Beta › Roll › Ubiquitin-like (UB roll) › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1 0.54 38.0 3.21e-01 87.7% 41.9%
5jk0B01 1.10.443.10 Mainly Alpha › Orthogonal Bundle › hpI Integrase; Chain A › Intergrase catalytic core 0.54 39.0 2.78e-01 77.2% 90.2%
1tg0A00 2.30.30.40 Mainly Beta › Roll › SH3 type barrels. › SH3 Domains 0.54 32.0 3.14e-01 70.2% 50.0%
4zg5A00 3.40.1210.10 Alpha Beta › 3-Layer(aba) Sandwich › Stationary-phase Survival Protein Sure Homolog; Chain: A, › Survival protein SurE-like phosphatase/nucleotidase 0.54 41.0 2.80e-01 87.7% 27.1%
1jb7A02 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.54 44.0 3.62e-01 98.2% 70.7%
1xttB00 3.40.50.2020 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.53 39.0 2.71e-01 80.7% 74.5%
1wi0A00 3.10.20.90 Alpha Beta › Roll › Ubiquitin-like (UB roll) › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1 0.52 40.0 3.40e-01 93.0% 85.8%
6aqgA01 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.52 42.0 3.36e-01 100.0% 56.0%
3h20A01 3.30.1490.240 Alpha Beta › 2-Layer Sandwich › Dna Ligase; domain 1 › RepB DNA-primase, N-terminal domain 0.51 38.0 3.76e-01 96.5% 77.3%
3t91B00 3.60.40.10 Alpha Beta › 4-Layer Sandwich › Phosphatase 2c; domain 1 › PPM-type phosphatase domain 0.51 44.0 2.98e-01 98.2% 40.2%
7trwA01 3.40.190.10 Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › Periplasmic binding protein-like II 0.50 39.0 3.38e-01 91.2% 98.0%
3w1eA03 2.40.10.410 Mainly Beta › Beta Barrel › Thrombin, subunit H › FlgT, C-terminal domain 0.50 35.0 3.18e-01 78.9% 91.0%
ECOD (68)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4026211 252.2.1.1 a+b two layers › DNA-binding domain › GCC-box binding domain-like › GCC-box binding domain-like › AP2 0.93 75.0 8.02e-01 84.2% 98.0%
4024768 330.3.1.7 a+b two layers › dsRBD-like › Peptidyl-tRNA hydrolase domain-like › Peptidyl-tRNA hydrolase domain-like › AP2 0.92 77.0 7.85e-01 87.7% 92.7%
4029439 252.2.1.0 a+b two layers › DNA-binding domain › GCC-box binding domain-like › GCC-box binding domain-like 0.91 77.0 7.13e-01 91.2% 73.9%
4030552 252.2.1.0 a+b two layers › DNA-binding domain › GCC-box binding domain-like › GCC-box binding domain-like 0.90 69.0 5.92e-01 80.7% 55.3%
4029229 252.2.1.0 a+b two layers › DNA-binding domain › GCC-box binding domain-like › GCC-box binding domain-like 0.90 66.0 7.02e-01 77.2% 94.0%
4028716 252.2.1.0 a+b two layers › DNA-binding domain › GCC-box binding domain-like › GCC-box binding domain-like 0.87 73.0 5.38e-01 89.5% 40.0%
4029445 252.2.1.1 a+b two layers › DNA-binding domain › GCC-box binding domain-like › GCC-box binding domain-like › AP2 0.86 66.0 6.78e-01 80.7% 85.5%
4026200 252.2.1.0 a+b two layers › DNA-binding domain › GCC-box binding domain-like › GCC-box binding domain-like 0.80 70.0 6.50e-01 94.7% 77.1%
5064976 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.71 53.0 3.89e-01 82.5% 56.2%
169012 223.2.1.1 a+b three layers › Profilin-like › profilin-like › profilin-like › Profilin 0.69 57.0 4.07e-01 93.0% 32.4%
4995243 3501.1.1.1 a+b two layers › protein PCC1 › protein PCC1 › protein PCC1 › Pcc1 0.68 51.0 4.72e-01 82.5% 97.3%
4405858 2003.1.1.3 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › adh_short 0.68 45.0 2.81e-01 71.9% 12.4%
3999192 223.2.1.0 a+b three layers › Profilin-like › profilin-like › profilin-like 0.67 54.0 4.88e-01 89.5% 66.3%
5002351 304.48.1.1 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 0.65 48.0 2.89e-01 77.2% 13.6%
3237267 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.65 56.0 4.68e-01 100.0% 68.6%
3286928 245.2.1.0 a+b two layers › Ribonuclease PH domain 2-like › YbaB › YbaB 0.65 47.0 4.81e-01 77.2% 83.6%
4947471 206.1.1.0 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase 0.64 45.0 2.94e-01 73.7% 17.7%
5019536 3755.1.1.0 alpha bundles › YscO-like › Putative type III secretion protein YscO-related › Putative type III secretion protein YscO-related 0.63 44.0 2.91e-01 71.9% 25.3%
3213981 5001.1.1.1 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 0.63 51.0 3.16e-01 91.2% 31.1%
3587631 186.1.1.0 alpha arrays › lambda integrase-N-like › lambda integrase-N › lambda integrase-N 0.63 50.0 3.72e-01 91.2% 35.0%
4995715 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.62 51.0 3.45e-01 100.0% 40.0%
3164555 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.62 49.0 3.71e-01 98.2% 33.3%
3255946 220.1.1.0 beta barrels › PH domain-like › PH domain-like › PH domain-like 0.62 42.0 3.76e-01 75.4% 50.0%
5050853 2004.1.1.16 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Arf 0.62 51.0 3.35e-01 94.7% 20.7%
3225917 2498.1.1.23 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M49 0.62 48.0 2.72e-01 86.0% 19.4%
5038957 323.1.1.1 a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › 2-oxoacid_dh 0.61 44.0 2.92e-01 78.9% 86.5%
3203514 2484.1.1.24 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.61 51.0 3.76e-01 93.0% 34.2%
3838435 101.1.8.1 alpha arrays › HTH › HTH › DNA breaking-rejoining enzymes › Phage_integrase 0.61 43.0 3.69e-01 75.4% 47.4%
3423775 601.16.1.8 alpha bundles › Four-helical up-and-down bundle › FAT domain of focal adhesion kinase › FAT domain of focal adhesion kinase › DUF1218 0.61 51.0 3.79e-01 94.7% 83.9%
1211453 2498.1.1.23 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M49 0.61 46.0 2.63e-01 86.0% 19.0%
5018285 213.1.1.25 a+b three layers › Nat/Ivy › Acyl-CoA N-acyltransferases (Nat) › Acyl-CoA N-acyltransferases (Nat) › Acetyltransf_3 0.60 46.0 3.81e-01 86.0% 79.1%
3930150 5001.1.1.66 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Srg 0.60 49.0 3.18e-01 98.2% 52.3%
4353121 218.1.1.8 a+b two layers › Enolase-N/ribosomal protein › Enolase N-terminal domain-like › Enolase N-terminal domain-like › HrcA 0.60 48.0 4.08e-01 91.2% 56.0%
3704074 223.2.1.19 a+b three layers › Profilin-like › profilin-like › profilin-like › Intu_longin_1 0.59 47.0 3.44e-01 89.5% 31.5%
3430282 601.1.2.68 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › DUF1218 0.58 47.0 3.33e-01 87.7% 98.8%
4023956 3871.1.1.1 alpha duplicates or obligate multimers › PHIST › PHIST › PHIST › PRESAN 0.58 49.0 3.78e-01 94.7% 95.4%
4355046 218.1.1.8 a+b two layers › Enolase-N/ribosomal protein › Enolase N-terminal domain-like › Enolase N-terminal domain-like › HrcA 0.58 44.0 3.82e-01 89.5% 51.6%
4988423 4210.1.1.0 a+b two layers › WGR domain › WGR domain › WGR domain 0.58 45.0 4.12e-01 98.2% 65.0%
1684639 4955.1.1.0 a+b two layers › permuted ferredoxin-like domain in yeast RNA-polymerase beta-prime subunit › permuted ferredoxin-like domain in yeast RNA-polymerase beta-prime subunit › permuted ferredoxin-like domain in yeast RNA-polymerase beta-prime subunit 0.57 39.0 3.57e-01 70.2% 64.1%
3484153 2498.1.1.0 mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" 0.57 48.0 2.69e-01 93.0% 97.8%
4962375 2484.1.1.49 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Hydant_A_N 0.57 45.0 3.55e-01 98.2% 39.3%
4890942 2004.1.1.93 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Dynein_heavy 0.57 44.0 3.26e-01 98.2% 32.4%
3966747 325.1.4.3 a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Nicotinate/Quinolinate PRTase N-terminal domain-like › NAPRTase_N 0.56 43.0 3.32e-01 87.7% 73.1%
5068175 2484.1.1.49 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Hydant_A_N 0.56 47.0 3.75e-01 100.0% 75.4%
4945973 2484.1.1.49 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Hydant_A_N 0.56 46.0 3.65e-01 100.0% 71.9%
138326 101.1.8.2 alpha arrays › HTH › HTH › DNA breaking-rejoining enzymes › Topoisom_I 0.56 43.0 3.28e-01 84.2% 40.3%
3719707 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.56 43.0 2.88e-01 86.0% 57.1%
3391166 5001.1.1.1 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 0.56 46.0 2.82e-01 93.0% 75.6%
3963148 2.1.1.15 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › tRNA_anti-codon 0.55 40.0 3.47e-01 80.7% 47.0%
3981752 829.1.1.1 a+b duplicates or obligate multimers › NinB › NinB › NinB › NinB 0.55 43.0 3.40e-01 87.7% 68.5%
3591474 4106.1.1.1 few secondary structure elements › Zinc hairpin stack › Zinc hairpin stack › Zinc hairpin stack › DHHC 0.54 47.0 3.21e-01 100.0% 83.2%
3592085 4015.1.1.1 alpha complex topology › alpha-helical domain in sec1/munc18-like (SM) proteins › alpha-helical domain in sec1/munc18-like (SM) proteins › alpha-helical domain in sec1/munc18-like (SM) proteins › Sec1 0.54 45.0 2.89e-01 93.0% 29.2%
3284000 4107.1.1.2 alpha arrays › Jann2411-like › Jann2411-like › Jann2411-like › zf-CGNR 0.53 46.0 3.31e-01 100.0% 85.4%
3498724 2002.1.1.106 a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › GDPD 0.53 40.0 2.53e-01 84.2% 46.0%
3731198 219.1.1.110 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Peptidase_C1, Peptidase_C1_2 0.53 44.0 2.67e-01 100.0% 25.1%
3578208 4.1.1.0 beta barrels › SH3 › SH3 › SH3 0.53 33.0 3.37e-01 75.4% 60.0%
4028937 109.4.1.1255 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Adaptin_N, Cnd1 0.53 45.0 2.54e-01 94.7% 16.3%
3533796 2003.1.1.4 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains 0.52 43.0 2.76e-01 98.2% 46.7%
5018572 304.48.1.72 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_N 0.52 42.0 2.91e-01 87.7% 46.1%
3303184 206.1.1.20 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › PK_Tyr_Ser-Thr 0.52 38.0 2.31e-01 77.2% 12.0%
5039314 192.2.1.0 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin 0.52 44.0 3.23e-01 94.7% 64.5%
3918235 2003.1.1.3 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › adh_short 0.52 42.0 2.71e-01 98.2% 65.5%
4473615 513.1.1.1 a+b two layers › Obg GTP-binding protein C-terminal domain-like › Obg GTP-binding protein C-terminal domain › Obg GTP-binding protein C-terminal domain › DUF1967 0.51 39.0 3.36e-01 84.2% 56.4%
3213493 5001.1.1.1 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 0.51 44.0 2.74e-01 94.7% 61.3%
4138932 304.48.1.72 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_N 0.51 40.0 2.53e-01 87.7% 28.7%
4595166 5076.2.1.0 alpha complex topology › Mitochondrial ADP/ATP carrier-like › Putative sulfate permease CysZ › Putative sulfate permease CysZ 0.51 43.0 2.81e-01 91.2% 25.3%
3641356 221.1.1.44 a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like › Rad60-SLD 0.50 35.0 3.33e-01 89.5% 58.7%
3560843 221.1.1.0 a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like 0.50 40.0 3.30e-01 91.2% 54.5%