←Back to structures

HNH-family_endonuclease

Euk-Vir

Golden_Marseillevirus

HNH-family_endonuclease__YP_009310317__Golden_Marseillevirus__1720526

Identity

Accession:
YP_009310317 ↗
Protein ID:
HNH-family_endonuclease
Kingdom:
euk

Quality

74.3 mean pLDDT

Taxonomy

Bamfordvirae› Nucleocytoviricota› Megaviricetes› Pimascovirales› Marseilleviridae› Marseillevirus› Golden_Marseillevirus

TaxID: 1720526

Cluster

View cluster (3 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 411-477
PDB
Domain cluster: rep: HNH-family_endonuclease__YP_009345378__Noumeavirus__1955558__D401-468
CATH (40)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3jtzA00 3.30.160.390 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Integrase, DNA-binding domain 0.68 53.0 5.07e-01 85.1% 100.0%
1okjB01 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.65 46.0 3.84e-01 82.1% 40.9%
2xa7M01 3.30.450.60 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › 0.64 41.0 3.40e-01 74.6% 35.8%
3wxmB02 3.30.420.60 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › eRF1 domain 2 0.63 48.0 4.01e-01 83.6% 70.5%
6h5bB01 3.30.450.30 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › Dynein light chain 2a, cytoplasmic 0.63 45.0 3.78e-01 77.6% 44.5%
5uaoC00 3.50.50.60 Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain 0.62 50.0 3.07e-01 94.0% 36.0%
1fr3A00 2.40.50.100 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › RNA polymerase II/Efflux pump adaptor protein, barrel-sandwich hybrid domain 0.61 38.0 3.90e-01 70.1% 62.7%
1skoB00 3.30.450.30 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › Dynein light chain 2a, cytoplasmic 0.61 42.0 3.62e-01 77.6% 43.1%
4l5tB02 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.60 42.0 3.81e-01 73.1% 75.8%
3gceA00 2.102.10.10 Mainly Beta › 3-layer Sandwich › Rieske Iron-sulfur Protein › Rieske [2Fe-2S] iron-sulphur domain 0.59 38.0 3.30e-01 76.1% 41.3%
4c12A02 3.40.1190.10 Alpha Beta › 3-Layer(aba) Sandwich › UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase › Mur-like, catalytic domain 0.59 46.0 3.22e-01 88.1% 89.5%
2l6mA00 3.30.160.400 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › 0.58 44.0 3.92e-01 83.6% 88.1%
7yh1A01 3.30.450.30 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › Dynein light chain 2a, cytoplasmic 0.58 38.0 3.32e-01 73.1% 40.4%
2ltrA00 3.30.160.20 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › 0.58 47.0 4.06e-01 89.6% 66.7%
2j3tD01 3.30.450.70 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › 0.58 40.0 3.29e-01 74.6% 38.8%
5umbA01 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.57 45.0 3.35e-01 88.1% 73.5%
2jaeA01 3.50.50.60 Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain 0.57 49.0 3.59e-01 97.0% 94.1%
4e1pA00 3.30.60.230 Alpha Beta › 2-Layer Sandwich › Wheat Germ Agglutinin (Isolectin 2); domain 1 › Lsr2, dimerisation domain 0.57 39.0 4.24e-01 73.1% 89.1%
4ktwA00 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.57 49.0 3.80e-01 100.0% 60.0%
1a73A00 3.90.75.10 Alpha Beta › Alpha-Beta Complex › Homing Intron 3 (I-Ppo) Encoded Endonuclease; Chain A › Homing Intron 3 (I-ppo) Encoded Endonuclease; Chain A 0.57 40.0 3.03e-01 73.1% 56.2%
2wesA00 3.50.50.60 Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain 0.57 48.0 2.93e-01 98.5% 39.1%
1rpyB00 3.30.505.10 Alpha Beta › 2-Layer Sandwich › SHC Adaptor Protein › SH2 domain 0.56 47.0 4.36e-01 94.0% 95.3%
1g29102 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.56 34.0 3.85e-01 73.1% 86.7%
4qdiA02 3.40.1190.10 Alpha Beta › 3-Layer(aba) Sandwich › UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase › Mur-like, catalytic domain 0.56 44.0 3.13e-01 89.6% 34.9%
1h8mA00 3.30.450.50 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › Longin domain 0.56 42.0 3.33e-01 80.6% 40.7%
3nemA01 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.56 43.0 3.77e-01 85.1% 77.1%
1kaxA02 3.30.30.30 Alpha Beta › 2-Layer Sandwich › Defensin A-like › 0.56 34.0 3.68e-01 76.1% 72.7%
2lg1A02 2.30.29.30 Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 0.56 41.0 3.51e-01 80.6% 47.0%
3u1nB01 1.10.3210.10 Mainly Alpha › Orthogonal Bundle › Hypothetical protein af1432 › Hypothetical protein af1432 0.55 48.0 3.10e-01 100.0% 69.5%
4gnxB00 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.55 39.0 3.29e-01 77.6% 95.9%
2dmwA01 3.30.450.50 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › Longin domain 0.53 40.0 3.40e-01 92.5% 47.4%
2rrfA00 2.30.29.160 Mainly Beta › Roll › PH-domain like › Zinc finger FYVE domain-containing protein 21, C-terminal 0.53 44.0 3.59e-01 100.0% 46.8%
2lc4A00 2.30.30.830 Mainly Beta › Roll › SH3 type barrels. › 0.53 41.0 3.46e-01 83.6% 65.8%
2nugB02 3.30.160.20 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › 0.53 43.0 4.25e-01 89.6% 85.9%
8f5dA05 3.40.1190.10 Alpha Beta › 3-Layer(aba) Sandwich › UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase › Mur-like, catalytic domain 0.53 45.0 3.18e-01 97.0% 35.7%
1u3eM01 3.90.75.20 Alpha Beta › Alpha-Beta Complex › Homing Intron 3 (I-Ppo) Encoded Endonuclease; Chain A › 0.52 36.0 3.11e-01 71.6% 54.7%
4l2iB00 3.40.50.620 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HUPs 0.52 40.0 2.73e-01 85.1% 54.0%
3zl8A02 3.40.1190.10 Alpha Beta › 3-Layer(aba) Sandwich › UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase › Mur-like, catalytic domain 0.52 42.0 2.99e-01 92.5% 33.6%
3u1wA01 3.10.450.360 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.51 39.0 2.94e-01 86.6% 71.0%
3o0wA01 2.60.120.200 Mainly Beta › Sandwich › Jelly Rolls › 0.51 42.0 2.94e-01 94.0% 46.6%
ECOD (66)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4026211 252.2.1.1 ↗ a+b two layers › DNA-binding domain › GCC-box binding domain-like › GCC-box binding domain-like › AP2 0.93 63.0 7.27e-01 70.1% 100.0%
4026577 252.2.1.1 ↗ a+b two layers › DNA-binding domain › GCC-box binding domain-like › GCC-box binding domain-like › AP2 0.91 64.0 7.09e-01 73.1% 94.5%
4024768 330.3.1.7 ↗ a+b two layers › dsRBD-like › Peptidyl-tRNA hydrolase domain-like › Peptidyl-tRNA hydrolase domain-like › AP2 0.89 64.0 7.02e-01 74.6% 96.4%
4028791 252.2.1.1 ↗ a+b two layers › DNA-binding domain › GCC-box binding domain-like › GCC-box binding domain-like › AP2 0.89 68.0 7.45e-01 79.1% 100.0%
4029439 252.2.1.0 ↗ a+b two layers › DNA-binding domain › GCC-box binding domain-like › GCC-box binding domain-like 0.88 70.0 6.99e-01 83.6% 87.0%
4025434 252.2.1.1 ↗ a+b two layers › DNA-binding domain › GCC-box binding domain-like › GCC-box binding domain-like › AP2 0.88 65.0 6.24e-01 77.6% 73.3%
4030681 252.2.1.1 ↗ a+b two layers › DNA-binding domain › GCC-box binding domain-like › GCC-box binding domain-like › AP2 0.87 66.0 6.71e-01 79.1% 86.2%
4028013 252.2.1.1 ↗ a+b two layers › DNA-binding domain › GCC-box binding domain-like › GCC-box binding domain-like › AP2 0.87 75.0 7.19e-01 91.0% 85.3%
4027687 330.3.1.0 ↗ a+b two layers › dsRBD-like › Peptidyl-tRNA hydrolase domain-like › Peptidyl-tRNA hydrolase domain-like 0.85 66.0 7.28e-01 83.6% 100.0%
4023919 252.2.1.1 ↗ a+b two layers › DNA-binding domain › GCC-box binding domain-like › GCC-box binding domain-like › AP2 0.84 62.0 6.35e-01 77.6% 87.7%
4029445 252.2.1.1 ↗ a+b two layers › DNA-binding domain › GCC-box binding domain-like › GCC-box binding domain-like › AP2 0.81 61.0 6.69e-01 79.1% 96.4%
3164102 252.2.1.0 ↗ a+b two layers › DNA-binding domain › GCC-box binding domain-like › GCC-box binding domain-like 0.78 51.0 6.03e-01 95.5% 100.0%
4026802 252.2.1.0 ↗ a+b two layers › DNA-binding domain › GCC-box binding domain-like › GCC-box binding domain-like 0.75 65.0 5.28e-01 94.0% 63.3%
3979711 252.2.1.6 ↗ a+b two layers › DNA-binding domain › GCC-box binding domain-like › GCC-box binding domain-like › Arm-DNA-bind_2 0.72 52.0 5.27e-01 79.1% 78.5%
4007983 252.2.1.5 ↗ a+b two layers › DNA-binding domain › GCC-box binding domain-like › GCC-box binding domain-like › Arm-DNA-bind_3 0.68 55.0 4.96e-01 89.6% 85.3%
3242105 207.1.1.81 ↗ beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats › FTH 0.67 50.0 3.62e-01 82.1% 44.0%
1515939 244.1.1.6 ↗ a+b two layers › FAD-linked reductases, C-terminal domain-like › FAD-linked reductases-C › FAD-linked reductases-C › Amino_oxidase 0.66 38.0 2.40e-01 70.1% 11.9%
3496925 7568.1.1.0 ↗ a/b three-layered sandwiches › BRCT domain › BRCT domain › BRCT domain 0.65 44.0 3.04e-01 71.6% 47.1%
3620870 223.2.1.0 ↗ a+b three layers › Profilin-like › profilin-like › profilin-like 0.64 44.0 3.91e-01 77.6% 49.0%
3928803 4967.1.1.0 ↗ alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases 0.61 50.0 3.63e-01 92.5% 69.0%
3722269 330.1.1.1 ↗ a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like › dsrm 0.61 46.0 4.56e-01 82.1% 95.7%
4973804 220.1.1.0 ↗ beta barrels › PH domain-like › PH domain-like › PH domain-like 0.61 40.0 3.91e-01 71.6% 60.0%
5022421 2.1.1.15 ↗ beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › tRNA_anti-codon 0.61 42.0 3.48e-01 73.1% 59.2%
5076118 223.2.1.0 ↗ a+b three layers › Profilin-like › profilin-like › profilin-like 0.60 40.0 3.19e-01 91.0% 31.7%
5000498 896.1.1.1 ↗ a+b two layers › SRP9/14-like › Signal recognition particle alu RNA binding heterodimer SRP9/14-related › Signal recognition particle alu RNA binding heterodimer SRP9/14-related › Ribosomal_L38e 0.60 38.0 4.02e-01 70.1% 71.7%
4052768 3675.1.1.0 ↗ a+b complex topology › DNA gyrase subunit B insertion domain › DNA gyrase subunit B insertion domain › DNA gyrase subunit B insertion domain 0.60 43.0 3.27e-01 76.1% 56.0%
5044629 223.2.1.0 ↗ a+b three layers › Profilin-like › profilin-like › profilin-like 0.59 43.0 3.62e-01 77.6% 47.8%
5050909 223.2.1.0 ↗ a+b three layers › Profilin-like › profilin-like › profilin-like 0.59 41.0 3.34e-01 73.1% 40.0%
4980097 223.2.1.0 ↗ a+b three layers › Profilin-like › profilin-like › profilin-like 0.58 42.0 3.47e-01 76.1% 42.4%
4034138 7520.1.1.0 ↗ a/b three-layered sandwiches › CinA-like › CinA-like › CinA-like 0.58 48.0 3.92e-01 94.0% 90.2%
5072591 223.2.1.0 ↗ a+b three layers › Profilin-like › profilin-like › profilin-like 0.58 45.0 3.77e-01 92.5% 48.7%
4945493 223.2.1.0 ↗ a+b three layers › Profilin-like › profilin-like › profilin-like 0.58 42.0 3.47e-01 77.6% 43.2%
5075279 223.2.1.0 ↗ a+b three layers › Profilin-like › profilin-like › profilin-like 0.58 45.0 3.76e-01 91.0% 48.7%
4996855 223.2.1.0 ↗ a+b three layers › Profilin-like › profilin-like › profilin-like 0.58 41.0 3.40e-01 76.1% 43.2%
3707662 223.2.1.42 ↗ a+b three layers › Profilin-like › profilin-like › profilin-like › Synaptobrevin 0.57 50.0 3.75e-01 97.0% 72.7%
3234330 330.1.1.1 ↗ a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like › dsrm 0.57 46.0 3.95e-01 89.6% 63.6%
3678841 330.1.1.1 ↗ a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like › dsrm 0.57 43.0 4.03e-01 82.1% 78.8%
4091986 2484.1.1.37 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Pan_kinase 0.57 40.0 3.43e-01 88.1% 44.3%
3736764 3711.1.1.0 ↗ alpha bundles › LTXXQ motif family protein › LTXXQ motif family protein › LTXXQ motif family protein 0.56 45.0 3.33e-01 88.1% 36.7%
3231733 223.2.1.8 ↗ a+b three layers › Profilin-like › profilin-like › profilin-like › Sybindin 0.56 40.0 3.19e-01 76.1% 37.9%
5077660 223.2.1.0 ↗ a+b three layers › Profilin-like › profilin-like › profilin-like 0.56 45.0 3.52e-01 92.5% 40.0%
4947581 223.2.1.0 ↗ a+b three layers › Profilin-like › profilin-like › profilin-like 0.56 42.0 3.65e-01 91.0% 50.9%
3728783 223.2.1.15 ↗ a+b three layers › Profilin-like › profilin-like › profilin-like › Longin 0.56 41.0 3.31e-01 97.0% 38.6%
3882038 223.2.1.3 ↗ a+b three layers › Profilin-like › profilin-like › profilin-like › Clat_adaptor_s 0.56 43.0 3.30e-01 97.0% 36.1%
4978284 223.2.1.0 ↗ a+b three layers › Profilin-like › profilin-like › profilin-like 0.55 44.0 3.61e-01 91.0% 47.5%
3233504 206.1.1.20 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › PK_Tyr_Ser-Thr 0.55 44.0 2.93e-01 89.6% 76.7%
4454256 2.1.1.15 ↗ beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › tRNA_anti-codon 0.55 38.0 3.11e-01 74.6% 52.4%
4188283 325.1.7.0 ↗ a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif 0.55 39.0 3.72e-01 74.6% 76.2%
3238130 227.1.1.12 ↗ a+b two layers › DNA clamp › DNA clamp › DNA clamp › Rad9 0.55 39.0 3.01e-01 74.6% 55.2%
3600795 223.2.1.0 ↗ a+b three layers › Profilin-like › profilin-like › profilin-like 0.55 38.0 2.99e-01 71.6% 37.2%
3715965 223.2.1.8 ↗ a+b three layers › Profilin-like › profilin-like › profilin-like › Sybindin 0.55 37.0 2.94e-01 71.6% 34.7%
5051623 223.2.1.20 ↗ a+b three layers › Profilin-like › profilin-like › profilin-like › Fuz_longin_1 0.55 41.0 3.30e-01 79.1% 70.8%
5000550 5.1.4.43 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › FG-GAP_3 0.54 47.0 3.04e-01 98.5% 92.9%
5053655 223.2.1.0 ↗ a+b three layers › Profilin-like › profilin-like › profilin-like 0.54 38.0 3.10e-01 73.1% 37.8%
4962202 2484.1.1.49 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Hydant_A_N 0.54 41.0 3.36e-01 83.6% 66.7%
3839291 300.1.1.8 ↗ a+b three layers › Phospholipase D/nuclease › Phospholipase D/nuclease › Phospholipase D/nuclease › PLDc_2 0.53 45.0 3.11e-01 95.5% 66.4%
5049789 223.2.1.0 ↗ a+b three layers › Profilin-like › profilin-like › profilin-like 0.53 42.0 3.43e-01 92.5% 45.6%
5073031 223.2.1.0 ↗ a+b three layers › Profilin-like › profilin-like › profilin-like 0.53 42.0 3.33e-01 94.0% 40.7%
3244220 207.1.1.81 ↗ beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats › FTH 0.53 40.0 2.84e-01 82.1% 51.4%
5071231 223.2.1.0 ↗ a+b three layers › Profilin-like › profilin-like › profilin-like 0.52 41.0 3.27e-01 92.5% 41.4%
4028520 192.4.1.34 ↗ alpha bundles › Long alpha-hairpin › Ribosomal protein L29 (L29p) › Ribosomal protein L29 (L29p) › Pescadillo_N 0.52 38.0 3.05e-01 80.6% 71.3%
4129337 2.1.1.15 ↗ beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › tRNA_anti-codon 0.52 41.0 3.21e-01 92.5% 84.8%
4249934 2484.1.1.37 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Pan_kinase 0.51 39.0 3.29e-01 95.5% 46.7%
5076505 2.1.1.15 ↗ beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › tRNA_anti-codon 0.51 41.0 3.32e-01 92.5% 93.6%
1733393 244.1.1.8 ↗ a+b two layers › FAD-linked reductases, C-terminal domain-like › FAD-linked reductases-C › FAD-linked reductases-C › Trp_halogenase 0.51 35.0 3.15e-01 71.6% 76.3%
4890693 2002.4.1.1 ↗ a/b barrels › TIM beta/alpha-barrel › Nicotinate/Quinolinate PRTase C-terminal domain-like › Nicotinate/Quinolinate PRTase C-terminal domain-like › NAPRTase 0.50 40.0 2.64e-01 89.6% 69.0%
D2 medium residues 26-91
PDB
Domain cluster: rep: putative_HNH-family_endonuclease__YP_009094766__Melbournevirus__1560514__D15-66
D3 medium residues 184-246
PDB
Domain cluster: representative
CATH (61)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1txdA02 2.30.29.30 Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 0.71 53.0 4.25e-01 93.7% 41.3%
1rl2A01 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.70 42.0 4.48e-01 81.0% 67.9%
1b69A00 3.30.160.60 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Classic Zinc Finger 0.68 53.0 5.22e-01 85.7% 94.2%
3go2A01 3.30.390.10 Alpha Beta › 2-Layer Sandwich › Enolase-like; domain 1 › Enolase-like, N-terminal domain 0.68 51.0 4.31e-01 87.3% 46.5%
2ffgA00 3.30.720.20 Alpha Beta › 2-Layer Sandwich › Signal recognition particle alu RNA binding heterodimer, srp9/1 › Protein of unknown function DUF1797 0.67 54.0 5.04e-01 88.9% 71.2%
2jkgA00 3.30.450.30 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › Dynein light chain 2a, cytoplasmic 0.67 54.0 4.07e-01 92.1% 40.0%
3o6qA02 3.30.70.2720 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.66 49.0 4.14e-01 88.9% 45.6%
2zylA01 2.102.10.10 Mainly Beta › 3-layer Sandwich › Rieske Iron-sulfur Protein › Rieske [2Fe-2S] iron-sulphur domain 0.66 43.0 3.32e-01 82.5% 31.1%
1ci3M02 2.40.50.100 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › RNA polymerase II/Efflux pump adaptor protein, barrel-sandwich hybrid domain 0.66 43.0 4.45e-01 81.0% 72.4%
1hp7A01 2.30.39.10 Mainly Beta › Roll › Alpha-1-antitrypsin; domain 1 › Alpha-1-antitrypsin, domain 1 0.65 46.0 4.00e-01 74.6% 67.4%
2xrnA02 3.30.450.40 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › GAF domain 0.65 53.0 3.93e-01 93.7% 37.9%
1z47A03 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.64 40.0 4.38e-01 77.8% 81.6%
4tyzA00 2.30.29.30 Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 0.63 43.0 3.67e-01 85.7% 41.3%
2v95A02 2.30.39.10 Mainly Beta › Roll › Alpha-1-antitrypsin; domain 1 › Alpha-1-antitrypsin, domain 1 0.63 45.0 3.53e-01 74.6% 53.5%
5inwA02 2.30.39.10 Mainly Beta › Roll › Alpha-1-antitrypsin; domain 1 › Alpha-1-antitrypsin, domain 1 0.63 44.0 3.68e-01 74.6% 60.2%
3kf6A00 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.61 50.0 3.96e-01 92.1% 58.8%
2j3tD01 3.30.450.70 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › 0.61 49.0 3.83e-01 90.5% 41.0%
3cetB01 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.61 43.0 3.70e-01 79.4% 44.5%
6aqgA01 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.60 44.0 3.52e-01 81.0% 53.2%
4r9iA02 2.30.39.10 Mainly Beta › Roll › Alpha-1-antitrypsin; domain 1 › Alpha-1-antitrypsin, domain 1 0.60 43.0 3.69e-01 76.2% 64.0%
2zgyA01 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.60 44.0 3.25e-01 81.0% 51.7%
3k44B00 3.30.2450.30 Alpha Beta › 2-Layer Sandwich › Secreted effector protein pipB2 fold › 0.60 48.0 3.74e-01 88.9% 85.7%
7wffb01 2.70.98.10 Mainly Beta › Distorted Sandwich › Beta-galactosidase; Chain A, domain 5 › 0.60 46.0 2.97e-01 84.1% 86.8%
3zqsA01 3.10.110.10 Alpha Beta › Roll › Ubiquitin Conjugating Enzyme › Ubiquitin Conjugating Enzyme 0.60 48.0 4.38e-01 92.1% 92.0%
2uurA00 2.60.120.200 Mainly Beta › Sandwich › Jelly Rolls › 0.59 50.0 3.47e-01 93.7% 40.0%
1nbwA04 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.59 45.0 3.62e-01 84.1% 72.7%
1xksA00 2.130.10.10 Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › YVTN repeat-like/Quinoprotein amine dehydrogenase 0.59 45.0 2.77e-01 82.5% 20.1%
2ya0A01 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.58 44.0 3.51e-01 81.0% 66.4%
1b44D00 2.40.50.110 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › 0.58 45.0 3.78e-01 88.9% 49.1%
1gutA00 2.40.50.100 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › RNA polymerase II/Efflux pump adaptor protein, barrel-sandwich hybrid domain 0.58 39.0 3.85e-01 77.8% 64.2%
1y96A00 2.30.30.100 Mainly Beta › Roll › SH3 type barrels. › 0.58 41.0 3.81e-01 77.8% 68.6%
3c96A01 3.50.50.60 Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain 0.57 50.0 3.71e-01 100.0% 69.0%
5x6vF00 3.30.450.190 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › 0.57 45.0 3.80e-01 96.8% 48.3%
5l09B00 3.30.450.80 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › Transcription factor LuxR-like, autoinducer-binding domain 0.57 47.0 3.63e-01 98.4% 55.5%
2d42A02 3.10.450.380 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.57 40.0 3.96e-01 73.0% 96.9%
2vr5B01 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.57 47.0 3.58e-01 92.1% 53.0%
3f1sA02 2.30.39.10 Mainly Beta › Roll › Alpha-1-antitrypsin; domain 1 › Alpha-1-antitrypsin, domain 1 0.57 48.0 3.57e-01 92.1% 46.7%
2czoA00 3.30.1520.10 Alpha Beta › 2-Layer Sandwich › PX Domain › Phox-like domain 0.56 48.0 3.87e-01 100.0% 68.5%
6hoxA01 2.60.120.200 Mainly Beta › Sandwich › Jelly Rolls › 0.55 46.0 3.16e-01 93.7% 37.1%
4x30A02 2.30.39.10 Mainly Beta › Roll › Alpha-1-antitrypsin; domain 1 › Alpha-1-antitrypsin, domain 1 0.55 47.0 3.54e-01 92.1% 52.8%
1bqnA05 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.55 44.0 3.56e-01 92.1% 67.2%
1xmtA00 3.40.630.30 Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Gcn5-related N-acetyltransferase (GNAT) 0.55 38.0 3.35e-01 74.6% 48.4%
2hzrA00 2.40.128.20 Mainly Beta › Beta Barrel › Lipocalin › Calycin beta-barrel core domain 0.54 44.0 3.40e-01 93.7% 84.5%
1mtpA02 2.30.39.10 Mainly Beta › Roll › Alpha-1-antitrypsin; domain 1 › Alpha-1-antitrypsin, domain 1 0.54 39.0 3.50e-01 77.8% 67.0%
3a0oA03 2.70.98.70 Mainly Beta › Distorted Sandwich › Beta-galactosidase; Chain A, domain 5 › 0.54 45.0 2.98e-01 95.2% 88.6%
2xcmC00 2.60.40.790 Mainly Beta › Sandwich › Immunoglobulin-like › 0.54 37.0 3.31e-01 76.2% 50.0%
2wweA01 3.30.1520.10 Alpha Beta › 2-Layer Sandwich › PX Domain › Phox-like domain 0.54 47.0 4.03e-01 100.0% 74.0%
1ykdB02 3.30.450.40 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › GAF domain 0.54 45.0 3.30e-01 96.8% 64.2%
7q04F01 2.102.10.10 Mainly Beta › 3-layer Sandwich › Rieske Iron-sulfur Protein › Rieske [2Fe-2S] iron-sulphur domain 0.54 41.0 3.50e-01 85.7% 51.4%
2z3gB00 3.40.140.10 Alpha Beta › 3-Layer(aba) Sandwich › Cytidine Deaminase; domain 2 › Cytidine Deaminase, domain 2 0.53 41.0 3.32e-01 84.1% 72.4%
1lm0A00 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.53 39.0 3.42e-01 81.0% 63.4%
4ckbD03 2.40.50.830 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › 0.52 42.0 3.50e-01 98.4% 73.1%
1vhzA01 3.90.79.10 Alpha Beta › Alpha-Beta Complex › Nucleoside Triphosphate Pyrophosphohydrolase › Nucleoside Triphosphate Pyrophosphohydrolase 0.52 37.0 2.78e-01 77.8% 50.6%
2eigA00 2.60.120.200 Mainly Beta › Sandwich › Jelly Rolls › 0.52 42.0 2.88e-01 88.9% 68.7%
2jzlA00 2.30.60.10 Mainly Beta › Roll › HIV-inactivating Protein, Cyanovirin-n › Cyanovirin-N 0.52 36.0 3.13e-01 76.2% 87.4%
2qa4I01 3.30.1550.10 Alpha Beta › 2-Layer Sandwich › Ribosomal protein L11, N-terminal domain › Ribosomal protein L11/L12, N-terminal domain 0.52 28.0 2.95e-01 77.8% 52.7%
2y1sA00 2.30.60.10 Mainly Beta › Roll › HIV-inactivating Protein, Cyanovirin-n › Cyanovirin-N 0.52 38.0 3.31e-01 82.5% 91.7%
1zarA02 3.30.200.20 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 0.52 37.0 3.39e-01 74.6% 59.3%
5iroD00 2.60.40.3530 Mainly Beta › Sandwich › Immunoglobulin-like › 0.51 42.0 3.67e-01 95.2% 59.8%
3l8kA02 3.50.50.60 Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain 0.51 37.0 3.00e-01 77.8% 96.0%
1nltA03 2.60.260.20 Mainly Beta › Sandwich › HSP40/DNAj peptide-binding domain › Urease metallochaperone UreE, N-terminal domain 0.51 39.0 3.70e-01 93.7% 68.3%
ECOD (81)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4027687 330.3.1.0 ↗ a+b two layers › dsRBD-like › Peptidyl-tRNA hydrolase domain-like › Peptidyl-tRNA hydrolase domain-like 0.84 68.0 7.22e-01 85.7% 100.0%
4026200 252.2.1.0 ↗ a+b two layers › DNA-binding domain › GCC-box binding domain-like › GCC-box binding domain-like 0.84 71.0 6.82e-01 90.5% 88.6%
3506540 220.1.1.20 ↗ beta barrels › PH domain-like › PH domain-like › PH domain-like › PH_TFIIH 0.71 57.0 4.68e-01 90.5% 48.7%
4058734 218.1.1.8 ↗ a+b two layers › Enolase-N/ribosomal protein › Enolase N-terminal domain-like › Enolase N-terminal domain-like › HrcA 0.70 52.0 4.59e-01 85.7% 53.7%
3812379 1.1.1.27 ↗ beta barrels › cradle loop barrel › RIFT-related › acid protease › Asp, TAXi_N 0.69 41.0 2.71e-01 90.5% 16.2%
3260957 214.1.1.0 ↗ a+b two layers › SH2 › SH2 › SH2 0.69 53.0 4.21e-01 84.1% 74.6%
3707662 223.2.1.42 ↗ a+b three layers › Profilin-like › profilin-like › profilin-like › Synaptobrevin 0.69 58.0 4.32e-01 95.2% 72.1%
3629460 207.1.1.0 ↗ beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats 0.68 49.0 3.23e-01 95.2% 17.8%
4190453 223.1.1.7 ↗ a+b three layers › Profilin-like › sensor domains › sensor domains › Autoind_bind 0.67 52.0 3.81e-01 82.5% 47.9%
3610082 896.1.1.0 ↗ a+b two layers › SRP9/14-like › Signal recognition particle alu RNA binding heterodimer SRP9/14-related › Signal recognition particle alu RNA binding heterodimer SRP9/14-related 0.67 38.0 3.81e-01 74.6% 55.4%
3637147 2003.1.1.0 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains 0.66 56.0 3.67e-01 96.8% 78.1%
2983288 101.1.2.0 ↗ alpha arrays › HTH › HTH › winged helix domain 0.65 45.0 4.05e-01 73.0% 51.7%
3597823 330.16.1.3 ↗ a+b two layers › dsRBD-like › ODA16 N-terminal domain › ODA16 N-terminal domain › CEP19 0.64 46.0 4.46e-01 76.2% 77.1%
3534125 10.1.1.0 ↗ beta sandwiches › jelly-roll › Concanavalin A-like › Concanavalin A-like lectins/glucanases 0.64 54.0 3.67e-01 93.7% 38.2%
3224134 223.2.1.0 ↗ a+b three layers › Profilin-like › profilin-like › profilin-like 0.64 52.0 4.05e-01 95.2% 40.0%
5061951 66.1.1.4 ↗ beta sandwiches › ISP domain › ISP domain › ISP domain › FtrD-like 0.64 46.0 3.72e-01 82.5% 40.7%
3515855 391.1.1.0 ↗ few secondary structure elements › Fibronectin type I module-like › Fibronectin type I module-like › Fibronectin type I module 0.63 38.0 3.29e-01 71.4% 37.0%
3547439 4059.1.1.1 ↗ a+b complex topology › Serpins › Serpins › Serpins › Serpin 0.63 44.0 2.88e-01 74.6% 24.2%
3838435 101.1.8.1 ↗ alpha arrays › HTH › HTH › DNA breaking-rejoining enzymes › Phage_integrase 0.62 44.0 3.85e-01 74.6% 51.6%
5012885 10.1.1.35 ↗ beta sandwiches › jelly-roll › Concanavalin A-like › Concanavalin A-like lectins/glucanases › Laminin_G_3 0.62 50.0 3.44e-01 88.9% 35.5%
3368395 206.1.1.1 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase 0.62 51.0 3.31e-01 93.7% 39.1%
5017958 9.1.1.0 ↗ beta barrels › Lipocalins/Streptavidin › Lipocalins › Lipocalins 0.62 47.0 3.67e-01 85.7% 77.3%
4662143 10.1.1.17 ↗ beta sandwiches › jelly-roll › Concanavalin A-like › Concanavalin A-like lectins/glucanases › Laminin_G_2 0.61 53.0 3.57e-01 93.7% 37.3%
3913519 216.1.1.9 ↗ a+b two layers › UBC-like › UBC-like › UBC-like › FANCL_d2 0.61 51.0 4.39e-01 95.2% 61.0%
3748155 10.1.1.17 ↗ beta sandwiches › jelly-roll › Concanavalin A-like › Concanavalin A-like lectins/glucanases › Laminin_G_2 0.61 52.0 3.64e-01 93.7% 41.0%
4931302 802.1.1.0 ↗ a+b two layers › Hypothetical protein TM0160 › Hypothetical protein TM0160 › Hypothetical protein TM0160 0.61 39.0 4.21e-01 71.4% 82.0%
3815957 5.1.3.67 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed › FBA_1 0.61 43.0 2.78e-01 76.2% 98.8%
3820521 2004.1.1.1 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA 0.61 47.0 2.98e-01 82.5% 28.5%
3405285 394.1.1.0 ↗ few secondary structure elements › Invertebrate chitin-binding proteins › Invertebrate chitin-binding proteins › Invertebrate chitin-binding proteins 0.61 46.0 4.35e-01 85.7% 95.0%
4432262 319.1.1.3 ↗ beta sandwiches › HSP20-like › HSP20-like chaperones › HSP20-like chaperones › CS 0.61 42.0 3.39e-01 82.5% 37.5%
3607454 220.1.1.306 ↗ beta barrels › PH domain-like › PH domain-like › PH domain-like › PH_22 0.60 43.0 3.79e-01 77.8% 82.0%
3658595 2.1.1.130 ↗ beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › DUF223 0.60 41.0 4.04e-01 71.4% 68.6%
3487886 2485.2.1.0 ↗ a+b three layers › Thioredoxin-like › RNA 3'-terminal phosphate cyclase, RPTC, insert domain › RNA 3'-terminal phosphate cyclase, RPTC, insert domain 0.60 50.0 4.36e-01 98.4% 75.2%
3999192 223.2.1.0 ↗ a+b three layers › Profilin-like › profilin-like › profilin-like 0.60 46.0 4.32e-01 98.4% 67.5%
5078315 5.1.4.1 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › WD40 0.60 45.0 2.60e-01 81.0% 9.2%
3910338 10.1.1.0 ↗ beta sandwiches › jelly-roll › Concanavalin A-like › Concanavalin A-like lectins/glucanases 0.60 52.0 3.85e-01 100.0% 55.3%
4962375 2484.1.1.49 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Hydant_A_N 0.59 45.0 3.61e-01 84.1% 40.7%
3541447 10.1.1.0 ↗ beta sandwiches › jelly-roll › Concanavalin A-like › Concanavalin A-like lectins/glucanases 0.59 52.0 3.79e-01 100.0% 52.2%
1830108 2484.8.1.1 ↗ mixed a+b and a/b › Ribonuclease H-like › Separase pseudo-protease domain (PPD) › Separase pseudo-protease domain (PPD) › Peptidase_C50 0.59 47.0 3.12e-01 90.5% 71.2%
3220752 2.1.1.0 ↗ beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein 0.59 46.0 3.88e-01 85.7% 77.3%
3961395 2003.1.2.6 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › FAD/NAD(P)-binding domain › FMO-like,NAD_binding_8 0.59 52.0 3.07e-01 100.0% 82.1%
3787501 277.1.1.1 ↗ a+b two layers › PX domain › PX domain › PX domain › PX 0.59 51.0 3.91e-01 95.2% 83.6%
3941411 223.1.1.3 ↗ a+b three layers › Profilin-like › sensor domains › sensor domains › GAF 0.59 53.0 3.81e-01 98.4% 52.9%
3177990 4015.1.1.1 ↗ alpha complex topology › alpha-helical domain in sec1/munc18-like (SM) proteins › alpha-helical domain in sec1/munc18-like (SM) proteins › alpha-helical domain in sec1/munc18-like (SM) proteins › Sec1 0.59 52.0 3.40e-01 96.8% 55.3%
4028996 220.1.1.0 ↗ beta barrels › PH domain-like › PH domain-like › PH domain-like 0.59 40.0 3.20e-01 73.0% 33.8%
3991073 4.8.1.0 ↗ beta barrels › SH3 › Chromo domain-like › Chromo domain-like 0.58 35.0 3.74e-01 77.8% 69.1%
3704328 292.2.1.0 ↗ a+b two layers › RIP/Polo-box domain › Polo-box domain › Polo-box domain 0.58 43.0 3.98e-01 79.4% 69.9%
3664617 2.1.1.223 ↗ beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › PF28721 0.58 43.0 3.96e-01 81.0% 61.2%
4023956 3871.1.1.1 ↗ alpha duplicates or obligate multimers › PHIST › PHIST › PHIST › PRESAN 0.58 46.0 3.78e-01 92.1% 100.0%
3618450 319.1.1.0 ↗ beta sandwiches › HSP20-like › HSP20-like chaperones › HSP20-like chaperones 0.58 40.0 3.44e-01 82.5% 45.0%
3507420 2.1.1.0 ↗ beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein 0.58 42.0 3.76e-01 79.4% 70.5%
4026408 4.1.1.219 ↗ beta barrels › SH3 › SH3 › SH3 › LSM12_LSM 0.58 42.0 3.62e-01 77.8% 59.0%
3736330 2003.1.2.6 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › FAD/NAD(P)-binding domain › FMO-like,NAD_binding_8 0.58 50.0 2.96e-01 100.0% 92.4%
3197429 244.2.1.10 ↗ a+b two layers › FAD-linked reductases, C-terminal domain-like › FAD/NAD-linked reduatases, dimerisation (C-terminal) domain › FAD/NAD-linked reduatases, dimerisation (C-terminal) domain › NDH2_C 0.58 48.0 3.19e-01 100.0% 59.4%
4020029 2003.1.3.26 ↗ a/b three-layered sandwiches › Rossmann-like › Rossmann-related › Nucleotide-binding domain › FMO-like, NAD_binding_8 0.57 43.0 2.55e-01 82.5% 10.8%
3719687 220.1.1.0 ↗ beta barrels › PH domain-like › PH domain-like › PH domain-like 0.57 41.0 3.93e-01 77.8% 64.0%
4961195 223.2.1.0 ↗ a+b three layers › Profilin-like › profilin-like › profilin-like 0.57 47.0 3.86e-01 96.8% 49.6%
5077400 192.2.1.0 ↗ alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin 0.57 47.0 4.03e-01 93.7% 56.7%
5039314 192.2.1.0 ↗ alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin 0.56 48.0 3.57e-01 93.7% 68.4%
223811 3583.1.1.1 ↗ few secondary structure elements › FusB family Zn-binding domain › FusB family Zn-binding domain › FusB family Zn-binding domain › FBP_C 0.56 43.0 3.59e-01 87.3% 74.4%
3541856 376.1.3.1 ↗ few secondary structure elements › RING/U-box-like › RING/U-box-like › FYVE/PHD zinc finger › PHD 0.56 46.0 3.47e-01 88.9% 93.8%
2512825 10.1.1.25 ↗ beta sandwiches › jelly-roll › Concanavalin A-like › Concanavalin A-like lectins/glucanases › Toxin_R_bind_N 0.55 46.0 3.18e-01 93.7% 38.1%
4353121 218.1.1.8 ↗ a+b two layers › Enolase-N/ribosomal protein › Enolase N-terminal domain-like › Enolase N-terminal domain-like › HrcA 0.55 46.0 4.02e-01 93.7% 62.0%
5034090 192.2.1.0 ↗ alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin 0.55 48.0 3.58e-01 95.2% 67.7%
3412753 5.1.4.0 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed 0.55 47.0 2.94e-01 98.4% 50.5%
4933497 2.1.1.0 ↗ beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein 0.55 38.0 3.35e-01 74.6% 67.6%
4091216 3844.2.1.2 ↗ a+b two layers › hydrogenase expression protein-like › MybT EspG5 chaperone › MybT EspG5 chaperone › DUF5081 0.55 43.0 3.07e-01 88.9% 41.0%
3721277 207.1.1.0 ↗ beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats 0.54 44.0 2.92e-01 95.2% 43.2%
4997112 223.2.1.0 ↗ a+b three layers › Profilin-like › profilin-like › profilin-like 0.54 45.0 3.62e-01 98.4% 46.2%
1385077 223.1.1.3 ↗ a+b three layers › Profilin-like › sensor domains › sensor domains › GAF 0.54 45.0 3.37e-01 96.8% 69.4%
3638300 220.1.1.95 ↗ beta barrels › PH domain-like › PH domain-like › PH domain-like › VID27_PH 0.53 38.0 3.05e-01 77.8% 37.1%
4033192 2.1.1.0 ↗ beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein 0.53 42.0 3.47e-01 92.1% 77.7%
4964362 6030.1.1.1 ↗ a+b two layers › Middle domain of ribosomal protein S2-related protein › Middle domain of ribosomal protein S2-related protein › Middle domain of ribosomal protein S2-related protein › DR2241 0.53 42.0 3.52e-01 90.5% 90.0%
3928430 4.1.1.223 ↗ beta barrels › SH3 › SH3 › SH3 › KIF2A-like_1st 0.53 37.0 3.63e-01 73.0% 78.6%
4947615 3604.1.1.0 ↗ a+b two layers › Uncharacterized protein MK0293 C-terminal domain › Uncharacterized protein MK0293 C-terminal domain › Uncharacterized protein MK0293 C-terminal domain 0.53 37.0 3.69e-01 88.9% 72.3%
5057630 2008.1.1.107 ↗ a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › NERD 0.52 40.0 2.94e-01 82.5% 57.6%
3606266 5.1.4.0 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed 0.52 43.0 2.57e-01 92.1% 21.0%
3319006 101.1.2.497 ↗ alpha arrays › HTH › HTH › winged helix domain › PF25874 0.52 36.0 3.05e-01 73.0% 41.8%
3789268 192.2.1.0 ↗ alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin 0.52 44.0 3.29e-01 95.2% 70.0%
3926118 4.1.1.223 ↗ beta barrels › SH3 › SH3 › SH3 › KIF2A-like_1st 0.51 35.0 3.56e-01 73.0% 93.3%
4280539 109.21.1.8 ↗ alpha superhelices › Repetitive alpha hairpins › Nucleoporin NUP85/Nucleoporin NUP145 C-terminal domain › Nucleoporin NUP85/Nucleoporin NUP145 C-terminal domain › WD40 0.51 44.0 2.49e-01 96.8% 35.0%
D4 medium residues 252-342
PDB
Domain cluster: representative
CATH (7)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2db2A01 3.30.160.20 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › 0.57 43.0 4.32e-01 81.3% 92.6%
2a5hA03 6.20.120.40 Special › Other non-globular › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › 0.55 23.0 2.69e-01 85.7% 46.8%
1jnrB02 6.20.260.10 Special › Other non-globular › Signal recognition particle alu RNA binding heterodimer, srp9/1 › Adenylylsulphate reductase, beta subunit, C-terminal domain 0.54 24.0 2.51e-01 90.1% 42.2%
2dsyD00 3.30.160.250 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › 0.53 42.0 4.38e-01 85.7% 96.3%
4fd0A01 2.60.40.3630 Mainly Beta › Sandwich › Immunoglobulin-like › 0.53 28.0 3.02e-01 87.9% 57.0%
3sk1A02 3.30.720.110 Alpha Beta › 2-Layer Sandwich › Signal recognition particle alu RNA binding heterodimer, srp9/1 › 0.52 26.0 3.11e-01 91.2% 70.7%
1w2tA02 2.60.120.560 Mainly Beta › Sandwich › Jelly Rolls › Exo-inulinase; domain 1 0.51 35.0 3.16e-01 72.5% 94.0%
ECOD (6)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4959884 4100.1.1.0 ↗ a+b duplicates or obligate multimers › TTHA1013/TTHA0281-like › TTHA1013/TTHA0281-like › TTHA1013/TTHA0281-like 0.66 40.0 4.86e-01 75.8% 100.0%
4979564 331.1.1.0 ↗ a+b two layers › TBP-like › TATA-box binding protein-like › TATA-box binding protein-like 0.62 29.0 3.24e-01 94.5% 55.7%
4929701 4100.1.1.0 ↗ a+b duplicates or obligate multimers › TTHA1013/TTHA0281-like › TTHA1013/TTHA0281-like › TTHA1013/TTHA0281-like 0.60 39.0 4.64e-01 81.3% 100.0%
5001324 220.1.1.0 ↗ beta barrels › PH domain-like › PH domain-like › PH domain-like 0.54 37.0 3.57e-01 82.4% 61.0%
3577264 207.1.1.0 ↗ beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats 0.54 41.0 3.49e-01 81.3% 56.7%
3912274 1170.1.1.1 ↗ beta barrels › IL8-related › IL8-related › IL8 › IL8 0.53 32.0 3.58e-01 73.6% 78.6%
D5 medium residues 343-410
PDB
Domain cluster: rep: ON911716.1__UUV45277.1__X__00019__D2-75
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF13392.13 best HNH_3 32.0 1.00e-07 58.8% 67.4%