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HQ317390.1__AFK66629.1__COPG_00033__00033
Bact-VirHQ317390.1__AFK66629.1__COPG_00033__00033
Identity
- Accession:
- HQ317390 ↗
- Kingdom:
- phage
Quality
74.7
mean pLDDT
Taxonomy
TaxID: 765765
Cluster
Singleton — not in a non-trivial cluster
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 6-72
Domain cluster:
representative
CATH (57)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4a17U01 | 1.10.287.310 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.71 | 56.0 | 5.36e-01 | 83.6% | 85.7% |
| 1f5oA00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.68 | 57.0 | 4.55e-01 | 98.5% | 53.7% |
| 2fji101 | 1.10.357.50 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › | 0.66 | 58.0 | 4.06e-01 | 97.0% | 58.4% |
| 1b5lA00 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.66 | 51.0 | 3.91e-01 | 83.6% | 77.0% |
| 3u3iA02 | 1.20.58.1110 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.65 | 55.0 | 4.82e-01 | 98.5% | 79.6% |
| 2l3lA01 | 1.20.58.1250 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Tubulin Binding Cofactor C, N-terminal domain | 0.65 | 51.0 | 4.36e-01 | 85.1% | 64.2% |
| 6wb9201 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.65 | 54.0 | 3.53e-01 | 94.0% | 21.5% |
| 3zheA02 | 1.25.40.760 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.65 | 54.0 | 3.95e-01 | 98.5% | 40.1% |
| 4oydB00 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.65 | 53.0 | 4.34e-01 | 88.1% | 86.3% |
| 1irxA04 | 1.10.10.770 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › | 0.65 | 49.0 | 4.14e-01 | 80.6% | 53.7% |
| 1lwbA00 | 1.20.90.10 | Mainly Alpha › Up-down Bundle › Phospholipase A2 › Phospholipase A2 domain | 0.64 | 49.0 | 4.06e-01 | 83.6% | 73.8% |
| 2ntxA02 | 1.20.58.1310 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › PRONE domain, subdomain 2 | 0.64 | 58.0 | 4.97e-01 | 100.0% | 73.8% |
| 4g1tA02 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.63 | 44.0 | 4.64e-01 | 89.6% | 80.3% |
| 1elkA00 | 1.25.40.90 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.63 | 52.0 | 4.15e-01 | 98.5% | 52.3% |
| 4kb2A01 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.62 | 52.0 | 4.40e-01 | 91.0% | 86.2% |
| 4f0uA00 | 1.10.490.20 | Mainly Alpha › Orthogonal Bundle › Globin-like › Phycocyanins | 0.62 | 51.0 | 4.05e-01 | 98.5% | 50.0% |
| 2rldA00 | 1.20.1440.60 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 23S rRNA-intervening sequence | 0.62 | 52.0 | 4.34e-01 | 91.0% | 81.6% |
| 1jkvA01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.62 | 52.0 | 3.68e-01 | 91.0% | 80.2% |
| 1sj8A02 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.62 | 49.0 | 4.01e-01 | 86.6% | 79.5% |
| 4gpkB01 | 1.25.40.1000 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.61 | 46.0 | 4.08e-01 | 83.6% | 55.6% |
| 3uj9A00 | 3.40.50.150 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 | 0.61 | 53.0 | 3.51e-01 | 94.0% | 87.2% |
| 1ax8A00 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.61 | 49.0 | 3.84e-01 | 85.1% | 45.4% |
| 2xpzA04 | 1.25.40.320 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Peptidase M1, leukotriene A4 hydrolase/aminopeptidase C-terminal domain | 0.61 | 52.0 | 4.01e-01 | 100.0% | 52.7% |
| 1gcvA00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.61 | 51.0 | 4.15e-01 | 100.0% | 61.4% |
| 3qbrX00 | 1.10.437.10 | Mainly Alpha › Orthogonal Bundle › Apoptosis Regulator Bcl-x › Blc2-like | 0.61 | 51.0 | 4.00e-01 | 100.0% | 53.4% |
| 3k3uA00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.60 | 50.0 | 4.10e-01 | 98.5% | 76.6% |
| 2pmvA01 | 1.50.10.20 | Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase › | 0.59 | 51.0 | 3.48e-01 | 100.0% | 45.8% |
| 3ciaA04 | 1.25.40.320 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Peptidase M1, leukotriene A4 hydrolase/aminopeptidase C-terminal domain | 0.59 | 48.0 | 3.89e-01 | 98.5% | 44.3% |
| 2h7oA01 | 1.20.120.1330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Rac1-binding domain, N-terminal GTPase binding subdomain | 0.59 | 51.0 | 4.19e-01 | 97.0% | 77.2% |
| 2hjmA01 | 1.20.120.460 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › protein pf1176 like | 0.59 | 50.0 | 4.59e-01 | 91.0% | 91.9% |
| 2cqnA00 | 1.10.10.440 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › FF domain | 0.59 | 43.0 | 4.17e-01 | 79.1% | 77.9% |
| 2qgmA03 | 1.20.1440.30 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › Biosynthetic Protein domain | 0.59 | 49.0 | 4.13e-01 | 94.0% | 55.2% |
| 4rngC00 | 1.20.1280.290 | Mainly Alpha › Up-down Bundle › Monooxygenase › | 0.58 | 43.0 | 4.09e-01 | 82.1% | 86.7% |
| 2c41C01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.58 | 46.0 | 3.62e-01 | 89.6% | 89.9% |
| 1nfvA00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.58 | 46.0 | 3.52e-01 | 91.0% | 74.0% |
| 2vxxA00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.57 | 46.0 | 3.49e-01 | 91.0% | 77.9% |
| 2ds2D01 | 1.10.110.10 | Mainly Alpha › Orthogonal Bundle › Hydrophobic Seed Protein › Plant lipid-transfer and hydrophobic proteins | 0.57 | 39.0 | 4.19e-01 | 73.1% | 100.0% |
| 4gytA00 | 1.20.120.740 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › YgfB uncharacterised protein family PF03695 | 0.56 | 50.0 | 3.71e-01 | 100.0% | 63.3% |
| 2c2uA00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.56 | 38.0 | 2.93e-01 | 73.1% | 61.2% |
| 2ra1A03 | 1.20.58.770 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.56 | 44.0 | 4.54e-01 | 91.0% | 93.7% |
| 2khmA01 | 1.10.10.1350 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Spidroin domain, C-terminal domain | 0.56 | 46.0 | 4.10e-01 | 100.0% | 87.0% |
| 2lqgA00 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.56 | 48.0 | 3.77e-01 | 95.5% | 62.3% |
| 2vxdA00 | 1.10.10.2100 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Nucleophosmin, C-terminal domain | 0.56 | 39.0 | 4.18e-01 | 73.1% | 98.1% |
| 2chpA00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.55 | 44.0 | 3.51e-01 | 91.0% | 89.9% |
| 2mx8A01 | 1.10.274.70 | Mainly Alpha › Orthogonal Bundle › Enzyme I; Chain A, domain 2 › Spidroin, N-terminal domain | 0.55 | 46.0 | 4.00e-01 | 98.5% | 86.7% |
| 2f3oA00 | 3.20.70.20 | Alpha Beta › Alpha-Beta Barrel › Anaerobic Ribonucleotide-triphosphate Reductase Large Chain › | 0.55 | 45.0 | 2.61e-01 | 97.0% | 70.6% |
| 2lseA00 | 1.20.120.1360 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.55 | 45.0 | 3.97e-01 | 91.0% | 73.3% |
| 3eabE00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.55 | 47.0 | 4.31e-01 | 94.0% | 88.4% |
| 2kmfA01 | 1.20.58.810 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Photosystem II Pbs27 | 0.54 | 45.0 | 4.02e-01 | 95.5% | 72.5% |
| 2jaqA00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.54 | 47.0 | 3.45e-01 | 98.5% | 54.5% |
| 1z9hA03 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.54 | 45.0 | 3.59e-01 | 98.5% | 90.7% |
| 6ks6q01 | 1.10.560.10 | Mainly Alpha › Orthogonal Bundle › GROEL; domain 1 › GroEL-like equatorial domain | 0.54 | 48.0 | 3.18e-01 | 100.0% | 82.8% |
| 6b8hO01 | 1.10.520.20 | Mainly Alpha › Orthogonal Bundle › Peroxidase; domain 1 › N-terminal domain of the delta subunit of the F1F0-ATP synthase | 0.53 | 37.0 | 3.33e-01 | 74.6% | 100.0% |
| 3axjB01 | 1.20.58.190 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 1 | 0.53 | 44.0 | 3.55e-01 | 100.0% | 78.7% |
| 2qvaA01 | 1.20.58.190 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 1 | 0.53 | 46.0 | 3.78e-01 | 100.0% | 87.6% |
| 1oj7A02 | 1.20.1090.10 | Mainly Alpha › Up-down Bundle › Dehydroquinate synthase-like, alpha domain › Dehydroquinate synthase-like - alpha domain | 0.53 | 42.0 | 3.12e-01 | 92.5% | 70.6% |
| 2yqzA02 | 1.10.8.900 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › | 0.52 | 42.0 | 4.27e-01 | 97.0% | 92.6% |
ECOD (50)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4937522 | 3930.1.1.3 ↗ | alpha bundles › Helical bundle insertion in helicase domains › Helical bundle in Hef helicase › Helical bundle in Hef helicase › RNA_helicase_helical | 0.70 | 52.0 | 4.15e-01 | 86.6% | 41.6% |
| 3782664 | 5067.1.1.0 ↗ | alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain | 0.70 | 51.0 | 3.50e-01 | 79.1% | 37.1% |
| 3863014 | 109.23.1.3 ↗ | alpha superhelices › Repetitive alpha hairpins › C-terminal domain in vacuolar protein sorting-associated protein 54 › C-terminal domain in vacuolar protein sorting-associated protein 54 › BCD_RFX | 0.69 | 61.0 | 4.70e-01 | 100.0% | 67.3% |
| 4972578 | 109.23.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › C-terminal domain in vacuolar protein sorting-associated protein 54 › C-terminal domain in vacuolar protein sorting-associated protein 54 | 0.67 | 51.0 | 4.45e-01 | 80.6% | 69.7% |
| 4052114 | 604.27.1.0 ↗ | alpha bundles › Spectrin repeat-like › Triple-helical domain in insecticidal protein Cry1Ac › Triple-helical domain in insecticidal protein Cry1Ac | 0.67 | 55.0 | 5.49e-01 | 89.6% | 90.0% |
| 4169660 | 604.27.1.0 ↗ | alpha bundles › Spectrin repeat-like › Triple-helical domain in insecticidal protein Cry1Ac › Triple-helical domain in insecticidal protein Cry1Ac | 0.67 | 56.0 | 5.51e-01 | 89.6% | 90.0% |
| 3628323 | 109.4.1.1415 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › BCD_RFX | 0.66 | 58.0 | 4.37e-01 | 100.0% | 60.0% |
| 3780905 | 109.3.1.355 ↗ | alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › BCD_RFX | 0.66 | 57.0 | 4.56e-01 | 100.0% | 72.1% |
| 4370184 | 3758.2.1.1 ↗ | alpha bundles › Bacterial hemolysins-like › Biopolymer transport protein ExbB › Biopolymer transport protein ExbB › MotA_ExbB | 0.65 | 46.0 | 3.38e-01 | 76.1% | 81.5% |
| 4014888 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.64 | 55.0 | 3.66e-01 | 97.0% | 29.6% |
| 3612308 | 604.3.1.0 ↗ | alpha bundles › Spectrin repeat-like › BAG domain › BAG domain | 0.64 | 53.0 | 4.41e-01 | 89.6% | 57.5% |
| 4630964 | 610.1.1.1 ↗ | alpha arrays › ERP29 C domain-like › ERP29 C domain-like › ERP29 C domain-like › ERp29 | 0.64 | 47.0 | 4.62e-01 | 80.6% | 74.7% |
| 3259409 | 150.1.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin | 0.63 | 49.0 | 3.87e-01 | 83.6% | 40.7% |
| 3183435 | 109.4.1.1126 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_SYO1 | 0.63 | 55.0 | 3.72e-01 | 98.5% | 32.5% |
| 3409326 | 3930.1.1.6 ↗ | alpha bundles › Helical bundle insertion in helicase domains › Helical bundle in Hef helicase › Helical bundle in Hef helicase › Dicer_PBD | 0.63 | 51.0 | 4.02e-01 | 86.6% | 74.1% |
| 4032384 | 604.3.1.0 ↗ | alpha bundles › Spectrin repeat-like › BAG domain › BAG domain | 0.63 | 51.0 | 4.86e-01 | 89.6% | 87.5% |
| 3220115 | 109.59.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › Intraflagellar transport protein 80 (IFT80) C-terminal domain › Intraflagellar transport protein 80 (IFT80) C-terminal domain | 0.63 | 51.0 | 5.02e-01 | 98.5% | 86.7% |
| 4963427 | 604.2.1.0 ↗ | alpha bundles › Spectrin repeat-like › Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain › Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain | 0.62 | 53.0 | 4.62e-01 | 89.6% | 70.5% |
| 5047422 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.62 | 51.0 | 4.34e-01 | 88.1% | 83.8% |
| 4198477 | 3758.2.1.1 ↗ | alpha bundles › Bacterial hemolysins-like › Biopolymer transport protein ExbB › Biopolymer transport protein ExbB › MotA_ExbB | 0.62 | 44.0 | 3.10e-01 | 76.1% | 83.1% |
| 3549954 | 3930.1.1.0 ↗ | alpha bundles › Helical bundle insertion in helicase domains › Helical bundle in Hef helicase › Helical bundle in Hef helicase | 0.62 | 47.0 | 3.09e-01 | 83.6% | 22.0% |
| 3411779 | 109.25.1.7 ↗ | alpha superhelices › Repetitive alpha hairpins › GPCR-autoproteolysis inducing domain subdomain A › GPCR-autoproteolysis inducing domain subdomain A › PF26588 | 0.61 | 52.0 | 4.49e-01 | 100.0% | 75.7% |
| 3652633 | 3930.1.1.0 ↗ | alpha bundles › Helical bundle insertion in helicase domains › Helical bundle in Hef helicase › Helical bundle in Hef helicase | 0.61 | 46.0 | 3.74e-01 | 82.1% | 52.3% |
| 3408518 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.61 | 53.0 | 4.24e-01 | 94.0% | 54.4% |
| 3748301 | 109.23.1.3 ↗ | alpha superhelices › Repetitive alpha hairpins › C-terminal domain in vacuolar protein sorting-associated protein 54 › C-terminal domain in vacuolar protein sorting-associated protein 54 › BCD_RFX | 0.61 | 52.0 | 4.07e-01 | 100.0% | 64.5% |
| 2138684 | 2003.1.5.201 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_25, Methyltransf_31 | 0.60 | 52.0 | 3.47e-01 | 94.0% | 86.8% |
| 3194115 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.60 | 49.0 | 2.94e-01 | 100.0% | 22.5% |
| 3942852 | 3636.1.1.0 ↗ | a+b two layers › XPD arch domain › XPD arch domain › XPD arch domain | 0.60 | 51.0 | 3.64e-01 | 91.0% | 64.4% |
| 5010469 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.59 | 42.0 | 3.61e-01 | 100.0% | 47.6% |
| 3297572 | 109.4.1.1257 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR_1, PPR_2 | 0.59 | 51.0 | 3.92e-01 | 100.0% | 46.3% |
| 3597239 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.59 | 51.0 | 3.27e-01 | 100.0% | 40.6% |
| 3704321 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.59 | 50.0 | 4.63e-01 | 94.0% | 81.2% |
| 3192246 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.58 | 48.0 | 3.70e-01 | 89.6% | 79.3% |
| 4152389 | 206.1.1.17 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Kdo | 0.58 | 48.0 | 3.40e-01 | 98.5% | 80.4% |
| 3303572 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.57 | 48.0 | 3.79e-01 | 97.0% | 44.7% |
| 3968401 | 109.4.1.86 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › DUF924 | 0.57 | 49.0 | 3.62e-01 | 100.0% | 36.8% |
| 4963879 | 2003.1.5.66 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_11 | 0.57 | 48.0 | 3.38e-01 | 98.5% | 94.0% |
| 3345919 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.56 | 50.0 | 4.26e-01 | 100.0% | 71.8% |
| 3657582 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.56 | 49.0 | 3.75e-01 | 100.0% | 44.9% |
| 3669053 | 109.4.1.98 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.56 | 50.0 | 3.24e-01 | 100.0% | 26.1% |
| 3258934 | 301.6.1.0 ↗ | a+b three layers › Bacillus chorismate mutase-like › Tubulin C-terminal domain-like › Tubulin C-terminal domain-like | 0.55 | 48.0 | 3.35e-01 | 98.5% | 48.9% |
| 3664654 | 109.4.1.1 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › 14-3-3 | 0.55 | 49.0 | 3.73e-01 | 100.0% | 87.1% |
| 5032086 | 2006.1.4.50 ↗ | a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › DUF3368 | 0.55 | 46.0 | 3.46e-01 | 98.5% | 89.4% |
| 3505950 | 633.1.1.0 ↗ | alpha bundles › Bromodomain-like › Bromodomain › Bromodomain | 0.54 | 43.0 | 3.91e-01 | 86.6% | 80.0% |
| 4063722 | 2003.1.1.188 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › Methyltransf_12, KR | 0.54 | 46.0 | 2.68e-01 | 100.0% | 29.3% |
| 3342534 | 604.5.1.31 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › TRAM_LAG1_CLN8 | 0.54 | 47.0 | 3.25e-01 | 100.0% | 51.0% |
| 3678110 | 593.1.1.1 ↗ | alpha bundles › GroEL equatorial domain-like › GroEL equatorial domain-like › GroEL equatorial domain-like › Cpn60_TCP1 | 0.53 | 46.0 | 3.16e-01 | 98.5% | 84.2% |
| 5019263 | 4953.1.1.0 ↗ | beta barrels › L-aspartase C-terminal domain-like › L-aspartase C-terminal domain-like › L-aspartase C-terminal domain-like | 0.53 | 44.0 | 3.89e-01 | 91.0% | 88.0% |
| 3307044 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.53 | 39.0 | 3.52e-01 | 83.6% | 74.3% |
| 3676117 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.53 | 45.0 | 3.02e-01 | 97.0% | 27.2% |
D2
high
residues 111-185
Domain cluster:
representative
CATH (37)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1omvA01 | 1.10.238.10 | Mainly Alpha › Orthogonal Bundle › Recoverin; domain 1 › EF-hand | 0.74 | 51.0 | 4.90e-01 | 84.0% | 62.8% |
| 2b3tA01 | 1.10.8.10 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Ubiquitin-associated (UBA) domain | 0.72 | 55.0 | 5.31e-01 | 81.3% | 83.3% |
| 3eeeA00 | 3.90.1520.10 | Alpha Beta › Alpha-Beta Complex › H-NOX domain › H-NOX domain | 0.70 | 52.0 | 3.85e-01 | 78.7% | 31.9% |
| 6yetA01 | 1.10.238.10 | Mainly Alpha › Orthogonal Bundle › Recoverin; domain 1 › EF-hand | 0.70 | 54.0 | 5.06e-01 | 90.7% | 68.1% |
| 4fwiB00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.70 | 50.0 | 3.34e-01 | 77.3% | 22.3% |
| 2yz2B00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.66 | 49.0 | 3.39e-01 | 80.0% | 27.0% |
| 4hluD00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.65 | 47.0 | 3.29e-01 | 76.0% | 28.6% |
| 1nvmA02 | 1.10.8.60 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › | 0.64 | 42.0 | 4.40e-01 | 81.3% | 78.1% |
| 4huqA00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.63 | 45.0 | 3.09e-01 | 76.0% | 24.6% |
| 3t0yA01 | 1.10.1740.10 | Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif | 0.62 | 42.0 | 4.46e-01 | 70.7% | 86.4% |
| 4g1uD00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.62 | 51.0 | 3.56e-01 | 93.3% | 26.8% |
| 5v89A02 | 1.10.238.200 | Mainly Alpha › Orthogonal Bundle › Recoverin; domain 1 › Cullin, PONY binding domain | 0.61 | 48.0 | 4.40e-01 | 98.7% | 63.7% |
| 4yerA01 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.61 | 49.0 | 3.56e-01 | 89.3% | 43.8% |
| 8dv0A01 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.60 | 42.0 | 3.25e-01 | 74.7% | 47.8% |
| 3iieB03 | 1.10.1740.10 | Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif | 0.60 | 45.0 | 4.34e-01 | 80.0% | 75.3% |
| 1ufzA01 | 1.10.8.10 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Ubiquitin-associated (UBA) domain | 0.60 | 38.0 | 4.12e-01 | 81.3% | 82.8% |
| 2jmlA00 | 1.10.1660.10 | Mainly Alpha › Orthogonal Bundle › Multidrug-efflux Transporter Regulator; Chain: A; Domain 2 › | 0.60 | 47.0 | 4.61e-01 | 85.3% | 79.0% |
| 1s7hA02 | 3.30.70.930 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.59 | 46.0 | 4.51e-01 | 85.3% | 81.7% |
| 2w02B01 | 1.10.150.640 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › AcsD, thumb domain, helical bundle | 0.58 | 40.0 | 4.05e-01 | 70.7% | 98.6% |
| 1zq9A02 | 1.10.8.480 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › | 0.58 | 45.0 | 4.20e-01 | 88.0% | 81.6% |
| 2nr7A00 | 1.20.141.10 | Mainly Alpha › Up-down Bundle › Chitosanase, subunit A; domain 1 › Chitosanase, subunit A, domain 1 | 0.58 | 51.0 | 3.80e-01 | 100.0% | 79.4% |
| 4nqfA00 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.58 | 48.0 | 3.86e-01 | 90.7% | 74.5% |
| 1sxjE02 | 1.10.8.60 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › | 0.56 | 40.0 | 4.23e-01 | 82.7% | 87.5% |
| 6abqB00 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.56 | 38.0 | 3.41e-01 | 70.7% | 65.1% |
| 1qasA01 | 1.10.238.10 | Mainly Alpha › Orthogonal Bundle › Recoverin; domain 1 › EF-hand | 0.55 | 45.0 | 4.37e-01 | 98.7% | 80.7% |
| 2p3yA02 | 1.10.3360.10 | Mainly Alpha › Orthogonal Bundle › VPA0735-like fold › VPA0735-like domain | 0.55 | 41.0 | 3.63e-01 | 78.7% | 80.4% |
| 3vayA02 | 1.20.120.1600 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.55 | 43.0 | 4.16e-01 | 92.0% | 75.9% |
| 2gf4A00 | 1.20.1270.110 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Uncharacterised protein family UPF0058 | 0.55 | 44.0 | 4.26e-01 | 90.7% | 79.5% |
| 7oq4Z01 | 1.20.120.950 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Uncharacterised protein DUF5062 | 0.55 | 40.0 | 3.70e-01 | 78.7% | 70.4% |
| 4n4gA01 | 1.20.920.10 | Mainly Alpha › Up-down Bundle › Histone Acetyltransferase; Chain A › Bromodomain-like | 0.54 | 45.0 | 3.98e-01 | 93.3% | 66.7% |
| 2zxqA06 | 1.20.1270.70 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Designed single chain three-helix bundle | 0.54 | 42.0 | 4.39e-01 | 88.0% | 97.0% |
| 2ougA00 | 3.30.70.940 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › NusG, N-terminal domain | 0.53 | 46.0 | 3.82e-01 | 100.0% | 78.7% |
| 4hr1A00 | 1.20.1270.410 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.53 | 42.0 | 3.61e-01 | 85.3% | 79.7% |
| 1u0mA01 | 3.40.47.10 | Alpha Beta › 3-Layer(aba) Sandwich › Peroxisomal Thiolase; Chain A, domain 1 › Thiolase/Chalcone synthase | 0.53 | 45.0 | 3.37e-01 | 97.3% | 72.3% |
| 1v1gA00 | 1.10.238.10 | Mainly Alpha › Orthogonal Bundle › Recoverin; domain 1 › EF-hand | 0.52 | 45.0 | 3.45e-01 | 100.0% | 72.9% |
| 1zoyD00 | 1.20.1300.10 | Mainly Alpha › Up-down Bundle › 3 helical TM bundles of succinate and fumarate reductases › Fumarate reductase/succinate dehydrogenase, transmembrane subunit | 0.51 | 40.0 | 3.69e-01 | 86.7% | 84.3% |
| 1wdhA02 | 1.10.720.60 | Mainly Alpha › Orthogonal Bundle › Transcription Termination Factor Rho, Rna-binding Domain; Chain A, Domain 1 › | 0.51 | 37.0 | 3.38e-01 | 80.0% | 56.9% |
ECOD (45)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3509739 | 108.1.1.0 ↗ | alpha arrays › EF-hand › EF-hand-related › EF-hand | 0.82 | 64.0 | 6.84e-01 | 82.7% | 100.0% |
| 3486838 | 108.1.1.29 ↗ | alpha arrays › EF-hand › EF-hand-related › EF-hand › EF-hand_7 | 0.75 | 57.0 | 5.44e-01 | 88.0% | 70.6% |
| 3931317 | 108.1.1.0 ↗ | alpha arrays › EF-hand › EF-hand-related › EF-hand | 0.74 | 60.0 | 4.44e-01 | 96.0% | 34.4% |
| 4316395 | 2003.1.5.46 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › MTS | 0.74 | 57.0 | 3.85e-01 | 82.7% | 72.6% |
| 3931416 | 108.1.1.0 ↗ | alpha arrays › EF-hand › EF-hand-related › EF-hand | 0.69 | 55.0 | 4.90e-01 | 90.7% | 61.0% |
| 3387113 | 2004.1.1.5 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ABC_tran | 0.69 | 52.0 | 3.67e-01 | 80.0% | 43.5% |
| 3670216 | 108.1.1.113 ↗ | alpha arrays › EF-hand › EF-hand-related › EF-hand › EF-hand_5, EF-hand_6 | 0.69 | 52.0 | 5.01e-01 | 88.0% | 71.8% |
| 3720237 | 108.1.1.0 ↗ | alpha arrays › EF-hand › EF-hand-related › EF-hand | 0.69 | 51.0 | 5.15e-01 | 81.3% | 78.7% |
| 331054 | 2004.1.1.5 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ABC_tran | 0.68 | 49.0 | 3.37e-01 | 77.3% | 26.3% |
| 5024613 | 2004.1.1.5 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ABC_tran | 0.67 | 49.0 | 3.41e-01 | 77.3% | 42.3% |
| 3941557 | 2004.1.1.417 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ABC_tran, AAA_21 | 0.67 | 51.0 | 3.51e-01 | 81.3% | 39.6% |
| 4030506 | 108.1.1.0 ↗ | alpha arrays › EF-hand › EF-hand-related › EF-hand | 0.67 | 52.0 | 4.82e-01 | 93.3% | 67.4% |
| 5029464 | 142.1.1.0 ↗ | alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors | 0.66 | 54.0 | 5.33e-01 | 89.3% | 85.0% |
| 3768733 | 102.2.1.0 ↗ | alpha arrays › HhH/H2TH › H2TH › H2TH | 0.66 | 53.0 | 5.24e-01 | 97.3% | 83.7% |
| 4364993 | 2004.1.1.6 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ABC_tran,oligo_HPY | 0.65 | 49.0 | 2.92e-01 | 81.3% | 16.9% |
| 3883134 | 108.1.1.73 ↗ | alpha arrays › EF-hand › EF-hand-related › EF-hand › EF-hand_5+EF-hand_7 | 0.65 | 48.0 | 4.71e-01 | 84.0% | 73.8% |
| 3629072 | 108.1.1.21 ↗ | alpha arrays › EF-hand › EF-hand-related › EF-hand › SPARC_Ca_bdg | 0.65 | 50.0 | 5.16e-01 | 93.3% | 90.0% |
| 5028806 | 2004.1.1.5 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ABC_tran | 0.64 | 48.0 | 3.33e-01 | 80.0% | 38.4% |
| 3796793 | 108.1.1.26 ↗ | alpha arrays › EF-hand › EF-hand-related › EF-hand › EF-hand_5 | 0.64 | 52.0 | 5.11e-01 | 97.3% | 83.7% |
| 3791538 | 108.1.1.0 ↗ | alpha arrays › EF-hand › EF-hand-related › EF-hand | 0.64 | 52.0 | 4.58e-01 | 97.3% | 60.9% |
| 3278774 | 142.1.1.3 ↗ | alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors › Sigma70_r2 | 0.62 | 53.0 | 4.82e-01 | 98.7% | 85.7% |
| 4531707 | 109.3.1.33 ↗ | alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › Ank_2,Ank_3 | 0.60 | 37.0 | 2.87e-01 | 82.7% | 26.9% |
| 3801576 | 4953.1.1.0 ↗ | beta barrels › L-aspartase C-terminal domain-like › L-aspartase C-terminal domain-like › L-aspartase C-terminal domain-like | 0.59 | 47.0 | 4.31e-01 | 89.3% | 66.0% |
| 5041714 | 102.2.1.3 ↗ | alpha arrays › HhH/H2TH › H2TH › H2TH › NFACT_N | 0.59 | 52.0 | 4.20e-01 | 100.0% | 64.0% |
| 3699807 | 108.1.1.27 ↗ | alpha arrays › EF-hand › EF-hand-related › EF-hand › EF-hand_6 | 0.59 | 48.0 | 4.33e-01 | 92.0% | 73.3% |
| 3527360 | 633.23.1.1 ↗ | alpha bundles › Bromodomain-like › Claudin › Claudin › PMP22_Claudin | 0.58 | 42.0 | 3.14e-01 | 77.3% | 66.7% |
| 5053673 | 101.1.9.0 ↗ | alpha arrays › HTH › HTH › Putative DNA-binding domain | 0.57 | 44.0 | 4.64e-01 | 85.3% | 100.0% |
| 4462712 | 103.1.1.6 ↗ | alpha arrays › RuvA-C › RuvA-C, UBA, CRAL/TRIO-N, HBS1 › UBA-like domain › RuvA_C | 0.57 | 38.0 | 4.11e-01 | 76.0% | 88.3% |
| 3620069 | 633.1.1.0 ↗ | alpha bundles › Bromodomain-like › Bromodomain › Bromodomain | 0.57 | 45.0 | 4.14e-01 | 97.3% | 64.8% |
| 5028356 | 601.7.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain | 0.56 | 41.0 | 3.63e-01 | 82.7% | 75.2% |
| 3353681 | 304.48.1.1 ↗ | a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 | 0.56 | 42.0 | 3.25e-01 | 82.7% | 70.6% |
| 3298619 | 108.1.1.1 ↗ | alpha arrays › EF-hand › EF-hand-related › EF-hand › EF-hand_1 | 0.55 | 45.0 | 4.27e-01 | 92.0% | 82.2% |
| 3592 | 632.12.1.1 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Vng1086c-like › Vng1086c-like › UPF0058 | 0.55 | 44.0 | 4.24e-01 | 90.7% | 78.7% |
| 3169508 | 309.1.1.1 ↗ | a+b two layers › LuxS, MPP, ThrRS/AlaRS common domain › LuxS, MPP, ThrRS/AlaRS common domain › LuxS/MPP-like metallohydrolase › Peptidase_M16 | 0.54 | 45.0 | 3.35e-01 | 93.3% | 76.0% |
| 3595497 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.53 | 42.0 | 2.96e-01 | 89.3% | 35.2% |
| 3282607 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.53 | 36.0 | 3.16e-01 | 70.7% | 45.6% |
| 4276306 | 309.1.1.1 ↗ | a+b two layers › LuxS, MPP, ThrRS/AlaRS common domain › LuxS, MPP, ThrRS/AlaRS common domain › LuxS/MPP-like metallohydrolase › Peptidase_M16 | 0.53 | 44.0 | 3.17e-01 | 94.7% | 66.0% |
| 5047749 | 601.28.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › VPS28 C-terminal domain-like › VPS28 C-terminal domain-like | 0.53 | 39.0 | 3.85e-01 | 82.7% | 78.8% |
| 3931888 | 633.1.1.1 ↗ | alpha bundles › Bromodomain-like › Bromodomain › Bromodomain › Bromodomain | 0.52 | 43.0 | 3.75e-01 | 97.3% | 71.2% |
| 3995944 | 2004.1.1.5 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ABC_tran | 0.52 | 40.0 | 2.46e-01 | 88.0% | 16.9% |
| 3976109 | 632.7.1.61 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain › BREX_BrxC_helical | 0.51 | 40.0 | 3.68e-01 | 89.3% | 100.0% |
| 5074496 | 601.28.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › VPS28 C-terminal domain-like › VPS28 C-terminal domain-like | 0.51 | 38.0 | 3.80e-01 | 84.0% | 81.2% |
| 3931889 | 633.1.1.1 ↗ | alpha bundles › Bromodomain-like › Bromodomain › Bromodomain › Bromodomain | 0.51 | 41.0 | 3.70e-01 | 96.0% | 78.3% |
| 3259425 | 103.1.1.3 ↗ | alpha arrays › RuvA-C › RuvA-C, UBA, CRAL/TRIO-N, HBS1 › UBA-like domain › CRAL_TRIO_N | 0.51 | 42.0 | 3.92e-01 | 93.3% | 78.9% |
| 3503962 | 4967.1.1.29 ↗ | alpha bundles › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › helical bundle domain in reverse transcriptase-like polymerases › DUF7047 | 0.50 | 39.0 | 3.84e-01 | 86.7% | 86.3% |