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HQ332139.1__AGF91538.1__PRRG_00027__00027
Bact-VirHQ332139.1__AGF91538.1__PRRG_00027__00027
Identity
- Accession:
- HQ332139 ↗
- Kingdom:
- phage
Quality
69.3
mean pLDDT
Taxonomy
TaxID: 756283
Cluster
Singleton — not in a non-trivial cluster
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 127-220
Domain cluster:
representative
CATH (61)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3p01A01 | 6.10.140.590 | Special › Helix non-globular › Helix Hairpins › | 0.73 | 56.0 | 5.93e-01 | 100.0% | 92.8% |
| 7dswA01 | 1.20.1530.20 | Mainly Alpha › Up-down Bundle › Na+/H+ antiporter like fold › | 0.72 | 59.0 | 3.89e-01 | 98.9% | 21.0% |
| 1ldjA03 | 1.20.1310.10 | Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats | 0.71 | 61.0 | 5.69e-01 | 97.9% | 77.4% |
| 4oydB00 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.68 | 62.0 | 5.74e-01 | 100.0% | 100.0% |
| 2wbiB03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.68 | 49.0 | 4.10e-01 | 74.5% | 91.8% |
| 4dveA00 | 1.10.1760.20 | Mainly Alpha › Orthogonal Bundle › Arp2/3 complex 21 kDa subunit ARPC3 › | 0.68 | 56.0 | 4.49e-01 | 90.4% | 78.3% |
| 8ek4A01 | 1.20.120.20 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein | 0.68 | 61.0 | 5.42e-01 | 100.0% | 97.7% |
| 1rx0A03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.66 | 45.0 | 3.82e-01 | 70.2% | 88.4% |
| 1n81A00 | 1.10.3030.10 | Mainly Alpha › Orthogonal Bundle › Gametocyte protein Pfg27 › Gametocyte protein Pfg27 | 0.66 | 55.0 | 4.41e-01 | 92.6% | 45.7% |
| 3lwjA00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.65 | 58.0 | 4.64e-01 | 100.0% | 60.1% |
| 2oerA00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.65 | 59.0 | 4.74e-01 | 100.0% | 59.8% |
| 4l8iB00 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.65 | 55.0 | 5.24e-01 | 94.7% | 99.1% |
| 2etdA00 | 1.20.1440.20 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › LemA-like domain | 0.65 | 45.0 | 4.00e-01 | 73.4% | 95.7% |
| 1wkbA03 | 1.10.730.10 | Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 | 0.62 | 48.0 | 4.43e-01 | 88.3% | 63.6% |
| 4okvE00 | 6.10.140.1890 | Special › Helix non-globular › Helix Hairpins › | 0.62 | 40.0 | 4.58e-01 | 71.3% | 93.8% |
| 8b70A01 | 1.20.1740.10 | Mainly Alpha › Up-down Bundle › Amino acid/polyamine transporter I › Amino acid/polyamine transporter I | 0.62 | 51.0 | 3.40e-01 | 93.6% | 57.4% |
| 4wqoD00 | 1.20.1310.10 | Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats | 0.61 | 53.0 | 4.73e-01 | 98.9% | 97.2% |
| 6o0aA01 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.61 | 53.0 | 4.52e-01 | 94.7% | 93.3% |
| 4abnA01 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.61 | 54.0 | 3.86e-01 | 98.9% | 92.5% |
| 1tj7A01 | 1.10.275.10 | Mainly Alpha › Orthogonal Bundle › Fumarase C; Chain B, domain 1 › Fumarase/aspartase (N-terminal domain) | 0.60 | 37.0 | 3.65e-01 | 73.4% | 55.2% |
| 1fewA00 | 1.20.58.70 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.60 | 53.0 | 4.39e-01 | 100.0% | 78.6% |
| 1a00B00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.60 | 47.0 | 4.07e-01 | 85.1% | 94.5% |
| 4v1gA00 | 1.20.20.10 | Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C | 0.59 | 41.0 | 4.25e-01 | 71.3% | 80.0% |
| 1sumB01 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.59 | 53.0 | 5.10e-01 | 100.0% | 99.1% |
| 1xwmA00 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.59 | 53.0 | 4.07e-01 | 98.9% | 49.5% |
| 2xubA05 | 6.10.140.1450 | Special › Helix non-globular › Helix Hairpins › | 0.59 | 41.0 | 4.14e-01 | 72.3% | 86.5% |
| 3l8rA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.59 | 51.0 | 5.00e-01 | 96.8% | 100.0% |
| 3edvA02 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.58 | 52.0 | 4.22e-01 | 100.0% | 60.7% |
| 3ihuA02 | 1.20.120.530 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › GntR ligand-binding domain-like | 0.58 | 48.0 | 4.28e-01 | 91.5% | 82.7% |
| 2imiB02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.58 | 50.0 | 4.44e-01 | 97.9% | 93.6% |
| 1b04A03 | 1.10.287.610 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.58 | 37.0 | 4.40e-01 | 80.9% | 100.0% |
| 2jbrA01 | 1.10.540.10 | Mainly Alpha › Orthogonal Bundle › Butyryl-Coa Dehydrogenase, subunit A; domain 1 › Acyl-CoA dehydrogenase/oxidase, N-terminal domain | 0.58 | 44.0 | 4.12e-01 | 83.0% | 64.7% |
| 4hehA01 | 1.10.1240.10 | Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › Methionine synthase domain | 0.58 | 40.0 | 4.24e-01 | 81.9% | 83.1% |
| 3d7iB00 | 1.20.1290.10 | Mainly Alpha › Up-down Bundle › AhpD-like › AhpD-like | 0.58 | 36.0 | 3.57e-01 | 84.0% | 58.2% |
| 1t72A01 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.58 | 51.0 | 4.76e-01 | 100.0% | 92.3% |
| 1fioA00 | 1.20.58.70 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.57 | 51.0 | 4.08e-01 | 100.0% | 59.5% |
| 1t6jA03 | 1.10.274.20 | Mainly Alpha › Orthogonal Bundle › Enzyme I; Chain A, domain 2 › Phenylalanine ammonia-lyase 1; domain 3 | 0.57 | 45.0 | 4.40e-01 | 89.4% | 77.7% |
| 2c0kB00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.57 | 46.0 | 4.03e-01 | 88.3% | 96.0% |
| 3vprA02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.57 | 49.0 | 4.26e-01 | 96.8% | 61.4% |
| 1urvA00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.57 | 48.0 | 4.12e-01 | 93.6% | 95.5% |
| 3ljbA00 | 1.20.120.1240 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Dynamin, middle domain | 0.56 | 49.0 | 3.79e-01 | 96.8% | 66.7% |
| 1hbgA00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.56 | 44.0 | 3.84e-01 | 85.1% | 95.9% |
| 2cmrA00 | 1.20.58.1860 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.56 | 49.0 | 3.95e-01 | 100.0% | 59.9% |
| 1wn0A00 | 1.20.120.160 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain | 0.56 | 43.0 | 3.93e-01 | 98.9% | 60.3% |
| 1yhuB00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.56 | 42.0 | 3.69e-01 | 80.9% | 93.1% |
| 4yonA01 | 1.20.900.10 | Mainly Alpha › Up-down Bundle › Dbl Homology Domain; Chain A › Dbl homology (DH) domain | 0.56 | 44.0 | 3.39e-01 | 85.1% | 89.4% |
| 1aepA00 | 1.20.120.20 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein | 0.55 | 46.0 | 3.94e-01 | 91.5% | 56.9% |
| 2odvA01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.55 | 48.0 | 4.61e-01 | 98.9% | 99.1% |
| 3pwxA01 | 1.20.1330.10 | Mainly Alpha › Up-down Bundle › f41 fragment of flagellin, N-terminal domain › f41 fragment of flagellin, N-terminal domain | 0.55 | 48.0 | 3.92e-01 | 100.0% | 55.4% |
| 1fpoC02 | 1.20.1280.20 | Mainly Alpha › Up-down Bundle › Monooxygenase › HscB, C-terminal domain | 0.54 | 44.0 | 4.55e-01 | 90.4% | 95.6% |
| 4qndA00 | 1.20.1280.290 | Mainly Alpha › Up-down Bundle › Monooxygenase › | 0.54 | 45.0 | 4.49e-01 | 96.8% | 88.7% |
| 3frrA00 | 1.20.1260.60 | Mainly Alpha › Up-down Bundle › Ferritin › Vacuolar protein sorting-associated protein Ist1 | 0.54 | 47.0 | 3.84e-01 | 100.0% | 90.3% |
| 2nwbA02 | 1.20.58.480 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.53 | 46.0 | 3.51e-01 | 98.9% | 69.2% |
| 1y4cA03 | 1.20.120.660 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › IL-4 antagonist (De novo design) like domain | 0.52 | 44.0 | 4.21e-01 | 97.9% | 80.5% |
| 3nbxX03 | 1.20.58.1510 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.52 | 44.0 | 4.40e-01 | 98.9% | 100.0% |
| 1vctA01 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.52 | 44.0 | 4.28e-01 | 95.7% | 92.7% |
| 3fmsA02 | 1.20.120.530 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › GntR ligand-binding domain-like | 0.52 | 42.0 | 3.73e-01 | 91.5% | 79.4% |
| 3c7jA02 | 1.20.120.530 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › GntR ligand-binding domain-like | 0.52 | 41.0 | 3.65e-01 | 89.4% | 78.8% |
| 1hciA01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.50 | 43.0 | 3.96e-01 | 96.8% | 87.3% |
| 1zymA02 | 1.10.274.10 | Mainly Alpha › Orthogonal Bundle › Enzyme I; Chain A, domain 2 › PtsI, HPr-binding domain | 0.50 | 38.0 | 3.53e-01 | 85.1% | 61.9% |
| 2hroA02 | 1.10.274.10 | Mainly Alpha › Orthogonal Bundle › Enzyme I; Chain A, domain 2 › PtsI, HPr-binding domain | 0.50 | 38.0 | 3.49e-01 | 85.1% | 60.2% |
ECOD (51)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3228465 | 604.4.1.0 ↗ | alpha bundles › Spectrin repeat-like › Alpha-hemoglobin stabilizing protein AHSP › Alpha-hemoglobin stabilizing protein AHSP | 0.79 | 70.0 | 6.72e-01 | 95.7% | 100.0% |
| 3903366 | 310.2.1.39 ↗ | a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF › PF25974 | 0.75 | 65.0 | 6.28e-01 | 94.7% | 99.0% |
| 3881044 | 621.1.1.8 ↗ | alpha bundles › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › GVIN1 | 0.73 | 65.0 | 6.24e-01 | 98.9% | 98.2% |
| 3899802 | 621.1.1.8 ↗ | alpha bundles › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › GVIN1 | 0.73 | 65.0 | 6.23e-01 | 98.9% | 99.1% |
| 3740986 | 621.1.1.3 ↗ | alpha bundles › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Sey1_3HB | 0.73 | 65.0 | 4.33e-01 | 100.0% | 31.2% |
| 4399510 | 621.1.1.0 ↗ | alpha bundles › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain | 0.72 | 65.0 | 4.96e-01 | 100.0% | 50.7% |
| 4944312 | 601.1.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin | 0.72 | 62.0 | 5.79e-01 | 94.7% | 83.5% |
| 4980095 | 310.2.1.0 ↗ | a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF | 0.71 | 56.0 | 5.41e-01 | 84.0% | 92.4% |
| 4886107 | 621.1.1.3 ↗ | alpha bundles › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Sey1_3HB | 0.71 | 59.0 | 5.84e-01 | 92.6% | 89.0% |
| 4405733 | 621.1.1.3 ↗ | alpha bundles › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Sey1_3HB | 0.70 | 62.0 | 5.12e-01 | 98.9% | 55.3% |
| 3889164 | 621.1.1.0 ↗ | alpha bundles › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain | 0.69 | 58.0 | 5.90e-01 | 93.6% | 96.7% |
| 3529162 | 601.1.1.53 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › Keratin_assoc | 0.68 | 60.0 | 5.58e-01 | 95.7% | 78.3% |
| 3706469 | 604.4.1.0 ↗ | alpha bundles › Spectrin repeat-like › Alpha-hemoglobin stabilizing protein AHSP › Alpha-hemoglobin stabilizing protein AHSP | 0.68 | 59.0 | 5.54e-01 | 97.9% | 88.7% |
| 4182059 | 621.1.1.3 ↗ | alpha bundles › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Sey1_3HB | 0.67 | 59.0 | 5.62e-01 | 98.9% | 92.7% |
| 3994046 | 129.1.1.9 ↗ | alpha arrays › 6-phosphogluconate dehydrogenase C-terminal domain-like › 6-phosphogluconate dehydrogenase C-terminal domain-like › 6-phosphogluconate dehydrogenase C-terminal domain-like › NAD_Gly3P_dh_C | 0.67 | 53.0 | 5.15e-01 | 86.2% | 81.0% |
| 3742628 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.66 | 60.0 | 5.05e-01 | 100.0% | 85.1% |
| 3606543 | 621.1.1.0 ↗ | alpha bundles › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain | 0.65 | 49.0 | 4.77e-01 | 80.9% | 86.7% |
| 3413723 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.64 | 57.0 | 5.57e-01 | 100.0% | 100.0% |
| 3596071 | 198.1.1.0 ↗ | alpha arrays › Saposin-like › Saposin-like › Saposin-like | 0.63 | 48.0 | 4.76e-01 | 80.9% | 85.0% |
| 3243484 | 532.2.1.0 ↗ | alpha arrays › Type III secretion system domain-like › Type III secretion system domains › Type III secretion system domains | 0.63 | 47.0 | 4.79e-01 | 79.8% | 88.9% |
| 3515126 | 3755.4.1.0 ↗ | alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain | 0.63 | 46.0 | 3.77e-01 | 77.7% | 83.4% |
| 5019967 | 1075.5.1.0 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter | 0.62 | 53.0 | 4.22e-01 | 93.6% | 55.3% |
| 5072135 | 2498.1.1.10 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M48 | 0.62 | 47.0 | 3.76e-01 | 80.9% | 67.7% |
| 3224983 | 106.1.1.1 ↗ | alpha arrays › Globin-like › Globin-like › Globin-like › Globin | 0.62 | 51.0 | 4.16e-01 | 90.4% | 87.0% |
| 3997392 | 106.1.1.1 ↗ | alpha arrays › Globin-like › Globin-like › Globin-like › Globin | 0.62 | 51.0 | 4.15e-01 | 89.4% | 87.2% |
| 3504889 | 604.22.1.1 ↗ | alpha bundles › Spectrin repeat-like › tubulin binding cofactor C N-terminal domain › tubulin binding cofactor C N-terminal domain › TBCC_N | 0.61 | 49.0 | 5.15e-01 | 94.7% | 100.0% |
| 2085171 | 4033.1.1.0 ↗ | alpha arrays › Acyl-CoA dehydrogenase N-terminal domain-like › Acyl-CoA dehydrogenase N-terminal domain-like › Acyl-CoA dehydrogenase N-terminal domain-like | 0.61 | 47.0 | 4.46e-01 | 85.1% | 69.3% |
| 3297061 | 632.1.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain | 0.60 | 38.0 | 3.60e-01 | 72.3% | 52.2% |
| 3257841 | 6155.1.1.2 ↗ | alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter › PQ-loop | 0.59 | 52.0 | 5.09e-01 | 97.9% | 89.0% |
| 3579748 | 3755.4.1.0 ↗ | alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain | 0.59 | 41.0 | 3.40e-01 | 72.3% | 41.2% |
| 3466553 | 1188.1.1.1 ↗ | alpha bundles › ZIP zinc transporter › ZIP zinc transporter › ZIP zinc transporter › Zip | 0.59 | 51.0 | 3.74e-01 | 100.0% | 33.3% |
| 4034409 | 1075.1.2.0 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › MacB transmembrane domain | 0.59 | 47.0 | 4.16e-01 | 89.4% | 86.2% |
| 5017736 | 3625.1.1.0 ↗ | alpha bundles › CRISPR RNA silencing complex Cmr2 subunit second helical domain › CRISPR RNA silencing complex Cmr2 subunit second helical domain › CRISPR RNA silencing complex Cmr2 subunit second helical domain | 0.59 | 43.0 | 4.16e-01 | 79.8% | 68.6% |
| 4936312 | 604.5.1.2 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU | 0.58 | 52.0 | 4.98e-01 | 100.0% | 96.4% |
| 1019365 | 604.5.1.2 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU | 0.58 | 51.0 | 4.84e-01 | 100.0% | 93.9% |
| 3988230 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.56 | 46.0 | 3.74e-01 | 92.6% | 88.2% |
| 3706209 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.56 | 49.0 | 4.27e-01 | 96.8% | 68.3% |
| 3607831 | 604.6.1.0 ↗ | alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain | 0.55 | 47.0 | 4.66e-01 | 94.7% | 96.0% |
| 3461781 | 1188.1.1.1 ↗ | alpha bundles › ZIP zinc transporter › ZIP zinc transporter › ZIP zinc transporter › Zip | 0.55 | 47.0 | 3.42e-01 | 97.9% | 40.0% |
| 3697268 | 6155.1.1.2 ↗ | alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter › PQ-loop | 0.55 | 48.0 | 4.48e-01 | 98.9% | 78.3% |
| 3634696 | 632.7.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain | 0.53 | 40.0 | 3.86e-01 | 85.1% | 68.2% |
| 3594110 | 3922.1.1.0 ↗ | alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 | 0.53 | 39.0 | 3.61e-01 | 76.6% | 90.0% |
| 3927006 | 603.1.1.99 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › PF27021 | 0.53 | 42.0 | 4.31e-01 | 88.3% | 100.0% |
| 5075236 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.53 | 46.0 | 4.30e-01 | 100.0% | 93.3% |
| 5041469 | 109.3.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat | 0.52 | 46.0 | 3.48e-01 | 98.9% | 41.3% |
| 4014383 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.52 | 43.0 | 3.83e-01 | 93.6% | 85.0% |
| 3408312 | 632.7.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain | 0.52 | 44.0 | 4.06e-01 | 93.6% | 71.7% |
| 3173484 | 633.21.1.17 ↗ | alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 › PFF1_TM | 0.52 | 40.0 | 3.80e-01 | 80.9% | 88.2% |
| 3883588 | 604.1.1.125 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › SYNRG_C | 0.51 | 44.0 | 3.68e-01 | 98.9% | 57.2% |
| 3924037 | 632.11.1.2 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like › DOCK_N | 0.51 | 40.0 | 4.02e-01 | 81.9% | 82.1% |
| 3308985 | 632.7.1.1 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain › HSP70 | 0.51 | 38.0 | 3.77e-01 | 80.9% | 74.0% |
D2
high
residues 233-368
Domain cluster:
representative
CATH (16)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2lhrA00 | 1.20.58.1270 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.65 | 28.0 | 3.66e-01 | 78.7% | 69.2% |
| 4q5nA02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.62 | 44.0 | 4.73e-01 | 83.8% | 88.4% |
| 5jrcA00 | 1.20.58.2140 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.59 | 41.0 | 3.73e-01 | 97.8% | 51.6% |
| 3g7rA00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.59 | 51.0 | 4.58e-01 | 94.1% | 89.4% |
| 8amzP01 | 1.25.40.570 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.58 | 39.0 | 2.92e-01 | 93.4% | 25.1% |
| 5cwhA01 | 1.25.10.10 | Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant | 0.57 | 37.0 | 3.62e-01 | 95.6% | 57.1% |
| 3zojA00 | 1.20.1080.10 | Mainly Alpha › Up-down Bundle › Glycerol uptake facilitator protein › Glycerol uptake facilitator protein. | 0.57 | 49.0 | 4.01e-01 | 95.6% | 68.8% |
| 4htpB00 | 1.10.3260.10 | Mainly Alpha › Orthogonal Bundle › DNA ligase i, domain 1 › DNA ligase, ATP-dependent, N-terminal domain | 0.56 | 46.0 | 3.95e-01 | 89.0% | 91.4% |
| 1orjD00 | 1.20.120.340 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Flagellar protein FliS | 0.56 | 35.0 | 3.68e-01 | 94.9% | 67.2% |
| 1s2xA00 | 1.20.190.30 | Mainly Alpha › Up-down Bundle › Delta-Endotoxin; domain 1 › CAG pathogenicity island protein, CagZ | 0.54 | 40.0 | 3.70e-01 | 77.9% | 92.8% |
| 1yw0A00 | 1.20.58.480 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.53 | 43.0 | 3.60e-01 | 88.2% | 80.2% |
| 3vwaA03 | 1.25.10.10 | Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant | 0.52 | 34.0 | 2.72e-01 | 96.3% | 30.2% |
| 1t98A02 | 1.20.58.590 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Chromosome partition protein MukF, middle domain | 0.52 | 41.0 | 3.88e-01 | 84.6% | 89.0% |
| 6ofsA02 | 3.30.830.10 | Alpha Beta › 2-Layer Sandwich › Cytochrome Bc1 Complex; Chain A, domain 1 › Metalloenzyme, LuxS/M16 peptidase-like | 0.51 | 38.0 | 3.28e-01 | 77.9% | 89.5% |
| 3dkaB01 | 1.20.120.450 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › dinb family like domain | 0.50 | 31.0 | 3.18e-01 | 77.2% | 60.7% |
| 3tdoA00 | 1.20.1080.10 | Mainly Alpha › Up-down Bundle › Glycerol uptake facilitator protein › Glycerol uptake facilitator protein. | 0.50 | 43.0 | 3.59e-01 | 97.1% | 95.7% |
ECOD (23)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4498171 | 101.11.1.1 ↗ | alpha arrays › HTH › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › PNPase | 0.69 | 33.0 | 4.32e-01 | 97.8% | 81.3% |
| 3258661 | 1075.1.2.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › MacB transmembrane domain › FtsX | 0.68 | 49.0 | 4.27e-01 | 74.3% | 74.1% |
| 4099178 | 1075.1.2.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › MacB transmembrane domain › FtsX | 0.66 | 47.0 | 4.45e-01 | 74.3% | 92.7% |
| 4595954 | 101.11.1.0 ↗ | alpha arrays › HTH › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 | 0.62 | 34.0 | 4.20e-01 | 97.8% | 84.7% |
| 4323909 | 101.11.1.1 ↗ | alpha arrays › HTH › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › PNPase | 0.62 | 36.0 | 4.19e-01 | 95.6% | 81.1% |
| 3644901 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.61 | 39.0 | 3.68e-01 | 100.0% | 51.8% |
| 4304782 | 101.11.1.1 ↗ | alpha arrays › HTH › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › PNPase | 0.58 | 33.0 | 4.04e-01 | 97.8% | 88.2% |
| 3215083 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.57 | 39.0 | 3.39e-01 | 83.8% | 42.2% |
| 3544887 | 627.1.1.1 ↗ | alpha complex topology › VPS9 domain › VPS9 domain › VPS9 domain › VPS9 | 0.57 | 42.0 | 4.10e-01 | 96.3% | 68.4% |
| 5077016 | 1075.1.2.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › MacB transmembrane domain › FtsX | 0.57 | 42.0 | 3.73e-01 | 77.2% | 100.0% |
| 4003345 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.56 | 47.0 | 3.65e-01 | 93.4% | 40.6% |
| 3181695 | 109.4.1.583 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › DNA_pol_phi | 0.55 | 46.0 | 3.71e-01 | 96.3% | 45.6% |
| 3604350 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.55 | 34.0 | 3.63e-01 | 89.7% | 70.0% |
| 4630984 | 101.11.1.1 ↗ | alpha arrays › HTH › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › PNPase | 0.55 | 31.0 | 3.70e-01 | 97.8% | 84.7% |
| 4045134 | 601.4.1.3 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains › 4HB_MCP_1 | 0.55 | 38.0 | 3.89e-01 | 94.9% | 73.8% |
| 3969049 | 601.4.1.3 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains › 4HB_MCP_1 | 0.54 | 38.0 | 3.57e-01 | 94.9% | 58.8% |
| 4025205 | 601.19.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Apolipoprotein › Apolipoprotein | 0.52 | 36.0 | 3.55e-01 | 71.3% | 72.0% |
| 3551590 | 109.4.1.1647 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PF28330 | 0.52 | 46.0 | 4.09e-01 | 96.3% | 96.9% |
| 3250607 | 627.1.1.1 ↗ | alpha complex topology › VPS9 domain › VPS9 domain › VPS9 domain › VPS9 | 0.52 | 43.0 | 4.07e-01 | 99.3% | 75.0% |
| 3396744 | 603.1.1.6 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Syntaxin_2 | 0.51 | 40.0 | 3.57e-01 | 83.1% | 93.8% |
| 5056292 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.51 | 34.0 | 3.59e-01 | 75.7% | 74.4% |
| 3252200 | 603.1.1.6 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Syntaxin_2 | 0.50 | 40.0 | 3.81e-01 | 84.6% | 88.1% |
| 1251943 | 601.1.2.1 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › Vinculin | 0.50 | 38.0 | 3.99e-01 | 86.8% | 86.4% |
D3
high
residues 522-628
Domain cluster:
representative
CATH (44)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3a06B03 | 1.10.1740.10 | Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif | 0.72 | 49.0 | 5.34e-01 | 100.0% | 85.2% |
| 2k3qA00 | 1.10.274.70 | Mainly Alpha › Orthogonal Bundle › Enzyme I; Chain A, domain 2 › Spidroin, N-terminal domain | 0.70 | 45.0 | 4.42e-01 | 97.2% | 59.3% |
| 2m6uA00 | 1.20.81.20 | Mainly Alpha › Up-down Bundle › Receptor-associated Protein › | 0.66 | 46.0 | 5.10e-01 | 96.3% | 92.7% |
| 3frrA00 | 1.20.1260.60 | Mainly Alpha › Up-down Bundle › Ferritin › Vacuolar protein sorting-associated protein Ist1 | 0.65 | 44.0 | 3.70e-01 | 70.1% | 66.7% |
| 2qywA00 | 1.20.58.400 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › t-snare proteins | 0.65 | 41.0 | 4.36e-01 | 75.7% | 71.6% |
| 1aj3A00 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.64 | 43.0 | 4.50e-01 | 75.7% | 74.5% |
| 3gi7A00 | 1.20.1270.180 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.64 | 49.0 | 5.01e-01 | 92.5% | 84.5% |
| 1cunA01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.63 | 43.0 | 4.45e-01 | 75.7% | 73.5% |
| 1sumB01 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.61 | 42.0 | 4.25e-01 | 78.5% | 70.1% |
| 1owaA02 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.61 | 42.0 | 4.29e-01 | 77.6% | 71.7% |
| 2rdcA00 | 1.10.287.800 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › protein ne1242 | 0.61 | 45.0 | 4.21e-01 | 77.6% | 71.4% |
| 4omfA00 | 1.10.645.10 | Mainly Alpha › Orthogonal Bundle › Cytochrome-c3 Hydrogenase; chain B › Cytochrome-c3 Hydrogenase, chain B | 0.60 | 45.0 | 3.04e-01 | 76.6% | 49.1% |
| 2i0mA01 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.60 | 39.0 | 3.99e-01 | 76.6% | 66.0% |
| 1u5pA01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.59 | 42.0 | 4.27e-01 | 80.4% | 73.1% |
| 5gj7A03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.59 | 41.0 | 3.67e-01 | 72.0% | 74.8% |
| 4gc0A01 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.58 | 46.0 | 3.53e-01 | 85.0% | 77.5% |
| 1t98A02 | 1.20.58.590 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Chromosome partition protein MukF, middle domain | 0.58 | 43.0 | 3.73e-01 | 77.6% | 58.9% |
| 1fioA00 | 1.20.58.70 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.58 | 41.0 | 3.44e-01 | 76.6% | 41.6% |
| 5nl6A02 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.57 | 40.0 | 3.99e-01 | 79.4% | 70.4% |
| 1zymA02 | 1.10.274.10 | Mainly Alpha › Orthogonal Bundle › Enzyme I; Chain A, domain 2 › PtsI, HPr-binding domain | 0.57 | 42.0 | 4.00e-01 | 76.6% | 94.4% |
| 3edvB01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.57 | 42.0 | 3.85e-01 | 80.4% | 59.6% |
| 3ck6C02 | 1.20.58.340 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region | 0.57 | 39.0 | 3.76e-01 | 74.8% | 62.2% |
| 1fewA00 | 1.20.58.70 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.56 | 43.0 | 3.68e-01 | 81.3% | 59.5% |
| 1u00A02 | 1.20.1270.10 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.56 | 38.0 | 4.06e-01 | 100.0% | 78.1% |
| 1bf5A01 | 1.20.1050.20 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › STAT transcription factor, all-alpha domain | 0.56 | 41.0 | 3.57e-01 | 76.6% | 64.9% |
| 1kl9A02 | 1.10.150.190 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Translation initiation factor 2; subunit 1; domain 2 | 0.56 | 39.0 | 4.12e-01 | 98.1% | 82.6% |
| 1r0dA00 | 1.20.1410.10 | Mainly Alpha › Up-down Bundle › I/LWEQ domain › I/LWEQ domain | 0.55 | 48.0 | 4.02e-01 | 98.1% | 87.6% |
| 4bemJ00 | 1.20.120.610 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › lithium bound rotor ring of v- atpase | 0.55 | 47.0 | 4.02e-01 | 97.2% | 56.4% |
| 4kc9A02 | 1.20.120.1750 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.54 | 40.0 | 3.18e-01 | 77.6% | 64.3% |
| 1gvnA00 | 1.10.8.130 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › | 0.54 | 39.0 | 4.22e-01 | 99.1% | 92.0% |
| 3mhsB00 | 1.10.246.140 | Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › ENY2/SUS1 | 0.54 | 36.0 | 3.84e-01 | 80.4% | 80.2% |
| 2qvwA04 | 1.10.1520.10 | Mainly Alpha › Orthogonal Bundle › Ribonuclease iii, N-terminal Endonuclease Domain; Chain A › Ribonuclease III domain | 0.53 | 48.0 | 4.38e-01 | 100.0% | 89.0% |
| 4ijjB00 | 1.20.120.910 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › DksA, coiled-coil domain | 0.53 | 44.0 | 4.13e-01 | 87.9% | 76.9% |
| 1cnt200 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.53 | 34.0 | 3.21e-01 | 86.0% | 53.1% |
| 3ls1A00 | 1.20.120.290 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Oxygen-evolving enhancer protein 3 (PsbQ), four-helix up-down bundle | 0.53 | 35.0 | 3.31e-01 | 95.3% | 54.9% |
| 4cqiA00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.52 | 39.0 | 3.90e-01 | 78.5% | 82.2% |
| 6o7uc01 | 1.20.120.610 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › lithium bound rotor ring of v- atpase | 0.52 | 45.0 | 3.79e-01 | 97.2% | 63.7% |
| 3a98A02 | 1.20.1270.350 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Dedicator of cytokinesis N-terminal subdomain | 0.51 | 35.0 | 3.82e-01 | 88.8% | 86.2% |
| 2ot4A03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.51 | 39.0 | 3.98e-01 | 97.2% | 80.4% |
| 2bl2A00 | 1.20.120.610 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › lithium bound rotor ring of v- atpase | 0.51 | 45.0 | 4.04e-01 | 100.0% | 78.8% |
| 4g80T00 | 1.20.120.350 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Voltage-gated potassium channels. Chain C | 0.51 | 37.0 | 3.45e-01 | 76.6% | 76.3% |
| 2d1lA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.50 | 45.0 | 3.43e-01 | 98.1% | 76.3% |
| 2c0kB00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.50 | 41.0 | 3.78e-01 | 92.5% | 94.6% |
| 2ddhA04 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.50 | 40.0 | 3.69e-01 | 83.2% | 69.7% |
ECOD (58)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3270180 | 5063.1.1.0 ↗ | alpha bundles › Photosystem I reaction center subunit X, PsaK › Photosystem I reaction center subunit X, PsaK › Photosystem I reaction center subunit X, PsaK | 0.74 | 49.0 | 5.34e-01 | 72.9% | 80.0% |
| 3794529 | 148.1.3.193 ↗ | alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain › TRAP-gamma | 0.74 | 64.0 | 5.69e-01 | 95.3% | 95.5% |
| 4216505 | 2003.1.1.0 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains | 0.72 | 53.0 | 4.00e-01 | 90.7% | 32.3% |
| 4943992 | 1075.1.2.0 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › MacB transmembrane domain | 0.71 | 50.0 | 4.19e-01 | 72.0% | 44.8% |
| 4216519 | 2003.1.1.0 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains | 0.71 | 53.0 | 3.94e-01 | 89.7% | 31.7% |
| 3576309 | 103.4.1.0 ↗ | alpha arrays › RuvA-C › Elongation factor TFIIS domain 2/ Kix domain of creb binding protein › Elongation factor TFIIS domain 2/ Kix domain of creb binding protein | 0.71 | 50.0 | 5.18e-01 | 96.3% | 78.0% |
| 4504853 | 547.1.1.0 ↗ | alpha duplicates or obligate multimers › Glutamyl tRNA-reductase dimerization domain › Glutamyl tRNA-reductase dimerization domain › Glutamyl tRNA-reductase dimerization domain | 0.69 | 50.0 | 5.16e-01 | 95.3% | 81.0% |
| 3974017 | 1075.1.2.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › MacB transmembrane domain › FtsX | 0.67 | 52.0 | 4.29e-01 | 82.2% | 55.8% |
| 4079949 | 2003.1.1.0 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains | 0.67 | 50.0 | 3.72e-01 | 87.9% | 31.9% |
| 3588971 | 6026.1.1.0 ↗ | alpha duplicates or obligate multimers › cwf21 domain › cwf21 domain › cwf21 domain | 0.66 | 44.0 | 5.09e-01 | 79.4% | 97.3% |
| None | — | 0.66 | 51.0 | 3.73e-01 | 91.6% | 31.6% | |
| 5040620 | 1075.1.2.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › MacB transmembrane domain › FtsX | 0.66 | 50.0 | 3.94e-01 | 80.4% | 43.6% |
| 4944939 | 5069.1.1.0 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes | 0.65 | 48.0 | 4.31e-01 | 76.6% | 89.3% |
| 4670167 | 547.1.1.1 ↗ | alpha duplicates or obligate multimers › Glutamyl tRNA-reductase dimerization domain › Glutamyl tRNA-reductase dimerization domain › Glutamyl tRNA-reductase dimerization domain › GlutR_dimer | 0.64 | 48.0 | 4.82e-01 | 89.7% | 77.3% |
| 3921752 | 5050.1.1.1 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr | 0.64 | 51.0 | 3.97e-01 | 86.0% | 75.3% |
| None | — | 0.64 | 49.0 | 3.64e-01 | 91.6% | 32.2% | |
| 3601437 | 5054.1.1.0 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels | 0.63 | 43.0 | 3.99e-01 | 70.1% | 78.5% |
| 5062487 | 1075.1.2.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › MacB transmembrane domain › FtsX | 0.63 | 50.0 | 4.28e-01 | 85.0% | 58.9% |
| 1019364 | 604.5.1.2 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU | 0.61 | 42.0 | 4.19e-01 | 78.5% | 67.6% |
| 3187995 | 603.1.1.3 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › V-SNARE | 0.61 | 39.0 | 3.94e-01 | 75.7% | 62.7% |
| 3577234 | 604.1.1.1 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin | 0.60 | 40.0 | 4.04e-01 | 73.8% | 67.6% |
| 4360723 | 632.7.1.1 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain › HSP70 | 0.60 | 39.0 | 4.27e-01 | 96.3% | 78.9% |
| 5026525 | 633.7.1.0 ↗ | alpha bundles › Bromodomain-like › Bacillus cereus metalloprotein-like › Bacillus cereus metalloprotein-like | 0.60 | 35.0 | 3.71e-01 | 87.9% | 64.3% |
| 3577228 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.59 | 43.0 | 4.19e-01 | 81.3% | 68.7% |
| 3504303 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.59 | 41.0 | 4.30e-01 | 78.5% | 77.0% |
| 3807101 | 3684.1.1.20 ↗ | alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › DUF4079 | 0.59 | 44.0 | 3.98e-01 | 77.6% | 80.0% |
| 3347764 | 105.1.1.45 ↗ | alpha duplicates or obligate multimers › HLH-like › HLH, helix-loop-helix DNA-binding domain › HLH, helix-loop-helix DNA-binding domain › PF26576 | 0.59 | 36.0 | 3.44e-01 | 99.1% | 52.0% |
| 3240453 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.59 | 41.0 | 4.21e-01 | 79.4% | 76.0% |
| 3548865 | 5050.1.1.8 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › FPN1 | 0.59 | 50.0 | 3.23e-01 | 92.5% | 67.4% |
| 3854050 | 604.12.1.43 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › Tim17 | 0.59 | 47.0 | 4.42e-01 | 100.0% | 69.6% |
| 4683095 | 632.7.1.1 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain › HSP70 | 0.58 | 39.0 | 4.51e-01 | 99.1% | 92.5% |
| 3862625 | 601.1.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin | 0.58 | 42.0 | 3.83e-01 | 74.8% | 76.4% |
| 4655075 | 632.7.1.1 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain › HSP70 | 0.58 | 38.0 | 4.14e-01 | 96.3% | 78.9% |
| 3575792 | 109.3.1.28 ↗ | alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › DC_STAMP | 0.58 | 51.0 | 4.27e-01 | 96.3% | 57.7% |
| 3228529 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.57 | 43.0 | 3.88e-01 | 79.4% | 83.3% |
| 3388455 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.57 | 44.0 | 4.35e-01 | 98.1% | 78.3% |
| 5047946 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.56 | 45.0 | 3.56e-01 | 85.0% | 80.9% |
| 3972080 | 4953.1.1.29 ↗ | beta barrels › L-aspartase C-terminal domain-like › L-aspartase C-terminal domain-like › L-aspartase C-terminal domain-like › DUF1631 | 0.56 | 51.0 | 4.31e-01 | 99.1% | 77.7% |
| 4946930 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.56 | 47.0 | 3.71e-01 | 91.6% | 80.0% |
| 4574698 | 632.18.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › hypothetical protein PA2901 › hypothetical protein PA2901 | 0.56 | 37.0 | 3.70e-01 | 98.1% | 63.5% |
| 3496310 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.56 | 40.0 | 3.86e-01 | 76.6% | 65.8% |
| 3477269 | 3755.4.1.0 ↗ | alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain | 0.56 | 39.0 | 3.49e-01 | 72.9% | 87.1% |
| 4628636 | 1075.1.1.4 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain › ABC2_membrane_3 | 0.56 | 48.0 | 3.64e-01 | 95.3% | 78.8% |
| 3221299 | 310.2.1.0 ↗ | a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF | 0.56 | 41.0 | 3.89e-01 | 79.4% | 71.1% |
| 5055115 | 4025.1.1.0 ↗ | alpha complex topology › alpha-helical domain in nickel-iron hydrogenase, large subunit › alpha-helical domain in nickel-iron hydrogenase, large subunit › alpha-helical domain in nickel-iron hydrogenase, large subunit | 0.56 | 40.0 | 3.17e-01 | 75.7% | 84.3% |
| 3257705 | 632.22.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats | 0.55 | 40.0 | 4.24e-01 | 87.9% | 85.3% |
| 5010966 | 1075.1.1.0 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain | 0.55 | 49.0 | 3.71e-01 | 100.0% | 63.5% |
| 3655293 | 622.4.1.0 ↗ | alpha bundles › YvfG-like › Mite allergen Der p 5-related › Mite allergen Der p 5-related | 0.55 | 48.0 | 3.88e-01 | 97.2% | 88.3% |
| 5055566 | 3922.1.1.0 ↗ | alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 | 0.54 | 50.0 | 4.86e-01 | 98.1% | 94.8% |
| 4505591 | 5050.1.1.25 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › TLC | 0.54 | 44.0 | 3.40e-01 | 87.9% | 75.5% |
| 4288763 | 5086.1.1.123 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › DUF445 | 0.54 | 39.0 | 3.46e-01 | 74.8% | 83.7% |
| 3880538 | 632.1.1.28 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain › DUF2678 | 0.52 | 38.0 | 4.17e-01 | 95.3% | 96.5% |
| 3564395 | 5031.1.1.4 ↗ | extended segments › Photosystem II reaction center protein J, PsbJ › Photosystem II reaction center protein J, PsbJ › Photosystem II reaction center protein J, PsbJ › Yip1 | 0.52 | 44.0 | 3.67e-01 | 97.2% | 98.0% |
| 3606622 | 1188.1.1.1 ↗ | alpha bundles › ZIP zinc transporter › ZIP zinc transporter › ZIP zinc transporter › Zip | 0.52 | 45.0 | 3.31e-01 | 97.2% | 78.7% |
| 3253663 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.52 | 41.0 | 3.92e-01 | 82.2% | 80.8% |
| 4393454 | 632.15.1.6 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Staphylococcal complement inhibitor (SCIN) › Staphylococcal complement inhibitor (SCIN) › DUF2678 | 0.52 | 38.0 | 3.97e-01 | 90.7% | 83.0% |
| 4282122 | 192.15.1.134 ↗ | alpha bundles › Long alpha-hairpin › Endosomal sorting complex assembly domains › Endosomal sorting complex assembly domains › PF27742 | 0.51 | 40.0 | 3.65e-01 | 84.1% | 66.9% |
| 4556245 | 607.1.1.1 ↗ | alpha arrays › Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain › Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain › Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain › PEP-utilisers_N | 0.50 | 40.0 | 3.95e-01 | 97.2% | 80.9% |
D4
high
residues 668-764
Domain cluster:
representative
CATH (13)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5domA00 | 1.10.110.10 | Mainly Alpha › Orthogonal Bundle › Hydrophobic Seed Protein › Plant lipid-transfer and hydrophobic proteins | 0.61 | 46.0 | 4.80e-01 | 90.7% | 88.9% |
| 2jepB00 | 3.20.20.80 | Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Glycosidases | 0.57 | 47.0 | 3.23e-01 | 92.8% | 34.5% |
| 1oe8A02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.55 | 43.0 | 4.01e-01 | 100.0% | 66.1% |
| 1d2zB00 | 1.10.533.10 | Mainly Alpha › Orthogonal Bundle › Death Domain, Fas › Death Domain, Fas | 0.54 | 39.0 | 3.43e-01 | 77.3% | 52.0% |
| 2vl7A02 | 1.10.275.30 | Mainly Alpha › Orthogonal Bundle › Fumarase C; Chain B, domain 1 › | 0.54 | 41.0 | 3.97e-01 | 81.4% | 88.2% |
| 3pasA00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.54 | 46.0 | 3.80e-01 | 100.0% | 79.5% |
| 1sg6A02 | 1.20.1090.10 | Mainly Alpha › Up-down Bundle › Dehydroquinate synthase-like, alpha domain › Dehydroquinate synthase-like - alpha domain | 0.53 | 38.0 | 3.01e-01 | 74.2% | 67.5% |
| 3bbyA02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.52 | 45.0 | 4.24e-01 | 96.9% | 80.3% |
| 3gehA02 | 1.20.120.430 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › tRNA modification GTPase MnmE domain 2 | 0.52 | 36.0 | 3.12e-01 | 73.2% | 78.4% |
| 3nivC02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.51 | 41.0 | 3.79e-01 | 100.0% | 67.7% |
| 7ccmB01 | 1.10.437.10 | Mainly Alpha › Orthogonal Bundle › Apoptosis Regulator Bcl-x › Blc2-like | 0.51 | 40.0 | 3.62e-01 | 88.7% | 62.9% |
| 4gltA02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.50 | 40.0 | 3.82e-01 | 100.0% | 74.6% |
| 2kmfA01 | 1.20.58.810 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Photosystem II Pbs27 | 0.50 | 37.0 | 3.64e-01 | 94.8% | 73.5% |
ECOD (14)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3479013 | 101.1.1.0 ↗ | alpha arrays › HTH › HTH › Three-helical HTH | 0.70 | 42.0 | 5.00e-01 | 72.2% | 89.2% |
| 3806923 | 185.1.1.4 ↗ | alpha superhelices › Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin-like › Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin/Protein HNS-dependent expression A HdeA › Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin › Prolamin_like | 0.69 | 54.0 | 5.48e-01 | 88.7% | 84.0% |
| 3477131 | 101.1.1.227 ↗ | alpha arrays › HTH › HTH › Three-helical HTH › HTH_NOL4_2nd | 0.68 | 42.0 | 4.83e-01 | 73.2% | 85.7% |
| 3785194 | 101.1.1.377 ↗ | alpha arrays › HTH › HTH › Three-helical HTH › PF29033 | 0.61 | 47.0 | 4.19e-01 | 81.4% | 85.9% |
| 1322519 | 101.1.2.188 ↗ | alpha arrays › HTH › HTH › winged helix domain › Roquin_1_2-like_ROQ | 0.61 | 36.0 | 3.69e-01 | 74.2% | 60.0% |
| 3240680 | 601.1.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › Vinculin | 0.58 | 42.0 | 3.81e-01 | 77.3% | 81.5% |
| 3457612 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.55 | 39.0 | 3.29e-01 | 74.2% | 89.4% |
| 3429545 | 3651.1.1.1 ↗ | alpha bundles › Translation initiation factor eIF-2B delta subunit N-terminal helical domain › Translation initiation factor eIF-2B delta subunit N-terminal helical domain › Translation initiation factor eIF-2B delta subunit N-terminal helical domain › IF-2B | 0.55 | 40.0 | 3.70e-01 | 95.9% | 60.0% |
| 3710221 | 197.1.1.7 ↗ | alpha bundles › Acyl-CoA binding protein-like › Acyl-CoA binding protein-like › Acyl-CoA binding protein-like › PriCT_2 | 0.54 | 39.0 | 3.81e-01 | 100.0% | 69.1% |
| 3191246 | 109.1.1.1 ↗ | alpha superhelices › Repetitive alpha hairpins › Glutathione S-transferase (GST)-C › Glutathione S-transferase (GST)-C › GST_C | 0.53 | 44.0 | 3.93e-01 | 100.0% | 64.3% |
| 4028749 | 627.1.1.1 ↗ | alpha complex topology › VPS9 domain › VPS9 domain › VPS9 domain › VPS9 | 0.53 | 42.0 | 3.72e-01 | 90.7% | 72.3% |
| 3291651 | 532.1.1.1 ↗ | alpha arrays › Type III secretion system domain-like › Antibiotic binding domain of TipA-like multidrug resistance regulators › Antibiotic binding domain of TipA-like multidrug resistance regulators › TipAS | 0.52 | 43.0 | 4.15e-01 | 95.9% | 90.4% |
| 3953728 | 101.1.1.202 ↗ | alpha arrays › HTH › HTH › Three-helical HTH › HTH_21 | 0.51 | 32.0 | 3.63e-01 | 71.1% | 90.8% |
| 5051817 | 2003.1.5.62 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Eco57I | 0.50 | 45.0 | 3.05e-01 | 100.0% | 29.0% |
D5
medium
residues 379-462
Domain cluster:
representative
CATH (27)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1cpzA00 | 3.30.70.100 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.70 | 33.0 | 3.61e-01 | 97.6% | 52.9% |
| 2xzmG00 | 1.10.455.10 | Mainly Alpha › Orthogonal Bundle › Ribosomal Protein S7 › Ribosomal protein S7/S5 | 0.69 | 41.0 | 3.14e-01 | 76.2% | 26.0% |
| 4mt1A07 | 3.30.70.1440 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Multidrug efflux transporter AcrB pore domain | 0.68 | 39.0 | 3.71e-01 | 98.8% | 46.1% |
| 3znuA00 | 3.30.70.1060 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Dimeric alpha+beta barrel | 0.66 | 39.0 | 3.75e-01 | 94.0% | 51.1% |
| 3h36A00 | 1.10.10.400 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Polyribonucleotide nucleotidyltransferase, RNA-binding domain | 0.66 | 52.0 | 5.40e-01 | 100.0% | 91.0% |
| 1ybtB00 | 3.30.70.1230 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Nucleotide cyclase, GGDEF domain | 0.64 | 46.0 | 3.59e-01 | 75.0% | 70.3% |
| 4mtnA01 | 3.30.1480.10 | Alpha Beta › 2-Layer Sandwich › N Utilization Substance Protein A; Chain:P; domain 4 › NusA, N-terminal domain | 0.63 | 39.0 | 3.73e-01 | 91.7% | 54.7% |
| 1y96D00 | 2.30.30.100 | Mainly Beta › Roll › SH3 type barrels. › | 0.60 | 33.0 | 3.40e-01 | 70.2% | 55.4% |
| 3aa0B01 | 1.20.58.570 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › F-actin capping protein, alpha/beta subunit, N-terminal domain | 0.58 | 41.0 | 4.03e-01 | 98.8% | 69.3% |
| 7dwqL01 | 1.20.1240.10 | Mainly Alpha › Up-down Bundle › Photosystem 1 Reaction Centre Subunit Xi; Chain: L; › Photosystem I PsaL, reaction centre subunit XI | 0.57 | 51.0 | 4.48e-01 | 100.0% | 78.4% |
| 3h8vB00 | 3.40.50.720 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain | 0.56 | 40.0 | 2.93e-01 | 75.0% | 49.1% |
| 1rz3A00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.56 | 48.0 | 3.82e-01 | 100.0% | 61.7% |
| 2yksA02 | 1.20.58.390 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Neurotransmitter-gated ion-channel transmembrane domain | 0.55 | 45.0 | 4.07e-01 | 100.0% | 64.1% |
| 5hdiA00 | 1.10.630.10 | Mainly Alpha › Orthogonal Bundle › Cytochrome p450 › Cytochrome P450 | 0.55 | 50.0 | 3.20e-01 | 100.0% | 31.7% |
| 1wp1B01 | 1.20.1600.10 | Mainly Alpha › Up-down Bundle › Outer membrane efflux proteins (OEP) › Outer membrane efflux proteins (OEP) | 0.55 | 48.0 | 3.20e-01 | 98.8% | 95.7% |
| 3cxjA00 | 3.30.1460.10 | Alpha Beta › 2-Layer Sandwich › Yope Regulator; Chain: A, › | 0.55 | 39.0 | 3.23e-01 | 100.0% | 43.1% |
| 2zdiC00 | 1.10.287.370 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.54 | 39.0 | 3.33e-01 | 77.4% | 58.1% |
| 4yt3A00 | 1.10.630.10 | Mainly Alpha › Orthogonal Bundle › Cytochrome p450 › Cytochrome P450 | 0.54 | 47.0 | 3.10e-01 | 100.0% | 66.5% |
| 3i6vA01 | 3.40.190.10 | Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › Periplasmic binding protein-like II | 0.54 | 33.0 | 2.86e-01 | 77.4% | 38.1% |
| 1io7A00 | 1.10.630.10 | Mainly Alpha › Orthogonal Bundle › Cytochrome p450 › Cytochrome P450 | 0.54 | 47.0 | 3.12e-01 | 100.0% | 66.9% |
| 3a32A02 | 3.40.50.800 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Anticodon-binding domain | 0.54 | 45.0 | 3.89e-01 | 96.4% | 96.5% |
| 7z67A01 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.54 | 47.0 | 3.52e-01 | 100.0% | 61.5% |
| 3nc3B00 | 1.10.630.10 | Mainly Alpha › Orthogonal Bundle › Cytochrome p450 › Cytochrome P450 | 0.52 | 45.0 | 2.99e-01 | 100.0% | 70.1% |
| 1jrmA00 | 3.30.1200.10 | Alpha Beta › 2-Layer Sandwich › Conserved Hypothetical Protein Mth637; Chain: A; › YggU-like | 0.52 | 35.0 | 3.34e-01 | 71.4% | 97.1% |
| 1x8dA01 | 3.30.70.100 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.52 | 31.0 | 2.99e-01 | 100.0% | 48.5% |
| 1hczA02 | 2.40.50.100 | Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › RNA polymerase II/Efflux pump adaptor protein, barrel-sandwich hybrid domain | 0.51 | 31.0 | 3.44e-01 | 92.9% | 83.1% |
| 2eabA02 | 1.50.10.10 | Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase › | 0.50 | 39.0 | 2.45e-01 | 84.5% | 28.0% |
ECOD (41)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3581467 | 167.1.1.1 ↗ | alpha arrays › Ribosomal protein S7 › Ribosomal protein S7 › Ribosomal protein S7 › Ribosomal_S7 | 0.72 | 41.0 | 3.49e-01 | 76.2% | 36.2% |
| 4948389 | 2004.1.1.164 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Roc | 0.68 | 40.0 | 3.27e-01 | 95.2% | 31.0% |
| 3408002 | 304.8.1.49 ↗ | a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › R1_ABCA1 | 0.66 | 38.0 | 3.51e-01 | 98.8% | 43.6% |
| 3604644 | 2004.1.1.712 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DUF87, HerA_C, TrwB_AAD_bind | 0.66 | 59.0 | 3.77e-01 | 100.0% | 21.5% |
| 3368067 | 109.4.1.583 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › DNA_pol_phi | 0.63 | 45.0 | 3.05e-01 | 100.0% | 19.7% |
| 3733878 | 109.4.1.819 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Sec8_C | 0.63 | 58.0 | 3.34e-01 | 100.0% | 12.4% |
| 3969345 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.62 | 43.0 | 3.14e-01 | 72.6% | 66.8% |
| 3243251 | 167.1.1.1 ↗ | alpha arrays › Ribosomal protein S7 › Ribosomal protein S7 › Ribosomal protein S7 › Ribosomal_S7 | 0.62 | 44.0 | 3.31e-01 | 73.8% | 65.5% |
| 3267765 | 4099.1.1.0 ↗ | a+b two layers › Kinetochore globular domain-like › Kinetochore globular domain-like › Kinetochore globular domain-like | 0.62 | 34.0 | 3.07e-01 | 76.2% | 40.9% |
| 3409778 | 192.2.1.2 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › Prefoldin | 0.61 | 41.0 | 3.63e-01 | 77.4% | 45.4% |
| 2755642 | 167.1.1.1 ↗ | alpha arrays › Ribosomal protein S7 › Ribosomal protein S7 › Ribosomal protein S7 › Ribosomal_S7 | 0.60 | 43.0 | 3.20e-01 | 73.8% | 60.6% |
| 3494833 | 5001.1.1.1 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 | 0.60 | 42.0 | 2.68e-01 | 73.8% | 55.3% |
| 3627712 | 5001.1.1.0 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like | 0.60 | 44.0 | 2.63e-01 | 76.2% | 28.2% |
| 4442629 | 3563.1.1.1 ↗ | alpha bundles › Twin arginine protein translocation system component TatC › Twin arginine protein translocation system component TatC › Twin arginine protein translocation system component TatC › TatC | 0.59 | 46.0 | 3.29e-01 | 100.0% | 28.3% |
| 3357805 | 3887.2.1.1 ↗ | a+b two layers › Yeast killer toxin-like › Antifungal protein ginkbilobin-2 › Antifungal protein ginkbilobin-2 › Stress-antifung | 0.57 | 41.0 | 4.33e-01 | 76.2% | 93.3% |
| 3860270 | 5001.1.1.5 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_3 | 0.57 | 42.0 | 2.94e-01 | 78.6% | 71.1% |
| 3215753 | 3226.1.1.1 ↗ | alpha complex topology › Uracil Transporter UraA › Uracil Transporter UraA › Uracil Transporter UraA › Xan_ur_permease | 0.57 | 48.0 | 3.08e-01 | 98.8% | 72.7% |
| 4387434 | 5064.1.1.1 ↗ | alpha bundles › Photosystem I reaction center subunit XI, PsaL › Photosystem I reaction center subunit XI, PsaL › Photosystem I reaction center subunit XI, PsaL › PsaL | 0.56 | 50.0 | 3.96e-01 | 100.0% | 57.8% |
| 3384050 | 601.1.1.91 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › DUF1218 | 0.56 | 41.0 | 3.26e-01 | 78.6% | 90.3% |
| 3787728 | 7.1.1.0 ↗ | beta barrels › PDZ domain › PDZ domain › PDZ domain | 0.55 | 39.0 | 4.16e-01 | 72.6% | 92.9% |
| 3463054 | 5050.1.1.108 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › PUCC, Nodulin-like, NFD4_C | 0.55 | 50.0 | 3.04e-01 | 100.0% | 59.8% |
| 4951776 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.54 | 41.0 | 3.91e-01 | 79.8% | 94.7% |
| 3472968 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.53 | 48.0 | 3.00e-01 | 100.0% | 18.5% |
| 3453219 | 109.3.1.2 ↗ | alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › Ank,Ank_2 | 0.53 | 40.0 | 2.91e-01 | 79.8% | 70.8% |
| 5040519 | 2.1.1.0 ↗ | beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein | 0.53 | 41.0 | 2.91e-01 | 83.3% | 43.1% |
| 3579987 | 220.1.1.160 ↗ | beta barrels › PH domain-like › PH domain-like › PH domain-like › PH_MADD | 0.52 | 41.0 | 3.85e-01 | 100.0% | 67.3% |
| 3592257 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.52 | 45.0 | 3.37e-01 | 96.4% | 54.4% |
| 3723552 | 109.4.1.356 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Fungal_trans | 0.52 | 44.0 | 2.86e-01 | 100.0% | 45.0% |
| 4988260 | 268.2.1.0 ↗ | a+b two layers › Sterol carrier protein-like › LytR-Cps2A-Psr (LCP) enzymes › LytR-Cps2A-Psr (LCP) enzymes | 0.52 | 43.0 | 3.26e-01 | 94.0% | 37.7% |
| 1697856 | 4963.1.1.3 ↗ | alpha complex topology › N-terminal additional helical subdomain in reovirus polymerase lambda3 › N-terminal additional helical subdomain in reovirus polymerase lambda3 › N-terminal additional helical subdomain in reovirus polymerase lambda3 › CPV_RdRP_N | 0.52 | 44.0 | 3.02e-01 | 100.0% | 82.6% |
| 4595166 | 5076.2.1.0 ↗ | alpha complex topology › Mitochondrial ADP/ATP carrier-like › Putative sulfate permease CysZ › Putative sulfate permease CysZ | 0.52 | 35.0 | 2.69e-01 | 71.4% | 60.4% |
| 3466238 | 206.1.1.14 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › ABC1 | 0.52 | 45.0 | 2.88e-01 | 100.0% | 81.8% |
| 4962836 | 5001.1.1.292 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › HisKA_7TM | 0.51 | 36.0 | 2.69e-01 | 75.0% | 34.7% |
| 4979121 | 3281.1.1.0 ↗ | alpha complex topology › Sodium/proton antiporter subunits-like › Sodium/proton antiporter subunits-like › NADH-quinone oxidoreductase subunit L (NuoL)-related | 0.51 | 44.0 | 2.59e-01 | 95.2% | 22.1% |
| 3310916 | 5069.1.1.55 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › DUF1218 | 0.51 | 37.0 | 2.99e-01 | 77.4% | 86.5% |
| 4304389 | 5086.1.1.119 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › RRG1_C | 0.51 | 38.0 | 2.74e-01 | 77.4% | 37.7% |
| 3484260 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.51 | 43.0 | 2.82e-01 | 92.9% | 25.1% |
| 3389668 | 220.1.1.160 ↗ | beta barrels › PH domain-like › PH domain-like › PH domain-like › PH_MADD | 0.51 | 40.0 | 3.83e-01 | 100.0% | 74.0% |
| 4987009 | 3837.1.1.1 ↗ | alpha bundles › Uncharacterized conserved protein Dip1984 › Uncharacterized conserved protein Dip1984 › Uncharacterized conserved protein Dip1984 › DUF6847 | 0.50 | 37.0 | 3.09e-01 | 78.6% | 44.7% |
| 3348024 | 109.4.1.583 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › DNA_pol_phi | 0.50 | 44.0 | 3.70e-01 | 100.0% | 57.3% |
| 3791945 | 5054.1.1.2 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › Ion_trans | 0.50 | 37.0 | 2.72e-01 | 78.6% | 29.8% |
D6
medium
residues 463-519
Domain cluster:
representative
CATH (33)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1dd5A01 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.74 | 63.0 | 5.20e-01 | 100.0% | 95.4% |
| 2xgcA02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.71 | 60.0 | 4.69e-01 | 96.5% | 60.9% |
| 1wpaA01 | 6.10.140.340 | Special › Helix non-globular › Helix Hairpins › | 0.71 | 48.0 | 3.98e-01 | 70.2% | 40.4% |
| 1vkeB00 | 1.20.1290.10 | Mainly Alpha › Up-down Bundle › AhpD-like › AhpD-like | 0.71 | 61.0 | 5.07e-01 | 98.2% | 59.4% |
| 2yx8A00 | 1.10.150.510 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Receptor activity modifying family | 0.68 | 54.0 | 4.97e-01 | 93.0% | 93.8% |
| 2mtqA00 | 1.20.58.130 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.68 | 56.0 | 5.25e-01 | 94.7% | 95.9% |
| 2wviA00 | 1.25.40.430 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.67 | 57.0 | 4.17e-01 | 96.5% | 53.8% |
| 6vudA01 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.67 | 57.0 | 4.72e-01 | 100.0% | 96.3% |
| 1c5aA00 | 1.20.91.20 | Mainly Alpha › Up-down Bundle › Influenza Virus Matrix Protein; Chain A, domain 1 › Anaphylotoxins (complement system) | 0.67 | 52.0 | 5.09e-01 | 94.7% | 78.5% |
| 2p4vA01 | 1.10.287.180 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Transcription elongation factor, GreA/GreB, N-terminal domain | 0.67 | 45.0 | 4.12e-01 | 70.2% | 60.5% |
| 3ehfD01 | 1.20.5.1930 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › | 0.66 | 44.0 | 4.33e-01 | 70.2% | 65.1% |
| 3sqiA01 | 1.10.150.540 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › | 0.66 | 55.0 | 4.68e-01 | 96.5% | 62.6% |
| 3anwA01 | 1.20.58.1030 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.66 | 51.0 | 4.09e-01 | 84.2% | 68.1% |
| 2kw6A00 | 6.10.140.1300 | Special › Helix non-globular › Helix Hairpins › | 0.65 | 43.0 | 4.19e-01 | 70.2% | 70.8% |
| 1rv2D04 | 1.10.287.690 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › B family DNA polymerase, finger domain | 0.64 | 43.0 | 4.06e-01 | 70.2% | 100.0% |
| 2d2sA02 | 1.20.58.1220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Exo84p, C-terminal helical domain | 0.64 | 52.0 | 4.46e-01 | 96.5% | 79.2% |
| 1vcsA00 | 1.20.58.400 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › t-snare proteins | 0.64 | 54.0 | 4.50e-01 | 96.5% | 92.2% |
| 4aifA00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.64 | 54.0 | 4.09e-01 | 96.5% | 59.0% |
| 4a8eA02 | 1.10.443.10 | Mainly Alpha › Orthogonal Bundle › hpI Integrase; Chain A › Intergrase catalytic core | 0.63 | 43.0 | 3.03e-01 | 71.9% | 81.6% |
| 3gxhA00 | 3.90.190.10 | Alpha Beta › Alpha-Beta Complex › Protein-Tyrosine Phosphatase; Chain A › Protein tyrosine phosphatase superfamily | 0.62 | 49.0 | 3.75e-01 | 94.7% | 91.7% |
| 3gziA00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.61 | 51.0 | 3.56e-01 | 96.5% | 51.2% |
| 4iw9A02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.60 | 49.0 | 3.97e-01 | 91.2% | 66.4% |
| 3v5uA01 | 6.10.280.80 | Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › NCX, peripheral helical region | 0.60 | 41.0 | 3.73e-01 | 71.9% | 90.8% |
| 3fnbA01 | 1.20.1440.110 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › acylaminoacyl peptidase | 0.59 | 50.0 | 4.06e-01 | 96.5% | 62.3% |
| 3r2kA00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.59 | 51.0 | 3.74e-01 | 96.5% | 49.4% |
| 2p5tA00 | 1.10.8.130 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › | 0.59 | 40.0 | 3.50e-01 | 71.9% | 48.9% |
| 5fhiA02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.58 | 48.0 | 3.76e-01 | 100.0% | 94.2% |
| 2jx0A00 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.58 | 48.0 | 3.75e-01 | 96.5% | 70.2% |
| 1wpbG01 | 1.10.287.680 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.57 | 40.0 | 4.09e-01 | 73.7% | 75.9% |
| 1lb3A00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.57 | 47.0 | 3.53e-01 | 100.0% | 82.0% |
| 1x2nA01 | 1.10.10.60 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like | 0.57 | 44.0 | 4.38e-01 | 93.0% | 86.7% |
| 2qkdA04 | 2.60.120.1040 | Mainly Beta › Sandwich › Jelly Rolls › ZPR1, A/B domain | 0.56 | 43.0 | 3.35e-01 | 84.2% | 48.0% |
| 1nktA04 | 1.10.3060.10 | Mainly Alpha › Orthogonal Bundle › Helical scaffold and wing domains of SecA › Helical scaffold and wing domains of SecA | 0.53 | 39.0 | 2.88e-01 | 87.7% | 27.1% |
ECOD (14)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4301189 | 3812.1.1.4 ↗ | alpha bundles › Type III secretion protein YscE › Type III secretion protein YscE › Type III secretion protein YscE › GrpE | 0.68 | 46.0 | 4.55e-01 | 70.2% | 81.7% |
| 4652719 | 3291.1.1.0 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related | 0.67 | 49.0 | 4.13e-01 | 77.2% | 90.5% |
| 5037511 | 2004.1.1.293 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_15 | 0.65 | 51.0 | 3.07e-01 | 91.2% | 12.4% |
| 3258173 | 101.1.1.0 ↗ | alpha arrays › HTH › HTH › Three-helical HTH | 0.64 | 47.0 | 4.82e-01 | 78.9% | 100.0% |
| 3674428 | 145.1.1.3 ↗ | alpha arrays › F-box domain › F-box domain › F-box domain › F-box-like | 0.60 | 49.0 | 4.85e-01 | 94.7% | 90.0% |
| 4680316 | 3694.1.1.0 ↗ | alpha bundles › Tail specific protease helical domain › Tail specific protease helical domain › Tail specific protease helical domain | 0.60 | 49.0 | 4.36e-01 | 89.5% | 86.3% |
| 3993978 | 192.7.1.0 ↗ | alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm | 0.59 | 39.0 | 3.73e-01 | 70.2% | 74.3% |
| 5048198 | 7000.1.1.0 ↗ | alpha arrays › inserted region in the C-terminal domain of the archeal LeuRS › inserted region in the C-terminal domain of the archeal LeuRS › inserted region in the C-terminal domain of the archeal LeuRS | 0.58 | 49.0 | 4.50e-01 | 94.7% | 85.3% |
| 5016327 | 605.1.1.2 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › H-kinase_dim | 0.58 | 39.0 | 3.70e-01 | 70.2% | 67.1% |
| 4586835 | 101.1.1.36 ↗ | alpha arrays › HTH › HTH › Three-helical HTH › Homeobox_KN | 0.57 | 46.0 | 4.43e-01 | 93.0% | 81.5% |
| 3170882 | 603.1.1.210 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Tmemb_170 | 0.55 | 47.0 | 3.77e-01 | 98.2% | 80.0% |
| 3612722 | 3932.1.1.0 ↗ | alpha bundles › CRISPR/Cas system-associated protein Csm6 6H domain › CRISPR/Cas system-associated protein Csm6 6H domain › CRISPR/Cas system-associated protein Csm6 6H domain | 0.54 | 41.0 | 4.14e-01 | 96.5% | 86.7% |
| 134553 | 191.1.1.0 ↗ | alpha bundles › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain | 0.53 | 41.0 | 3.47e-01 | 98.2% | 74.2% |
| 4494528 | 632.2.1.40 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Bacterial immunoglobulin/albumin-binding domains › Bacterial immunoglobulin/albumin-binding domains › DUF515 | 0.50 | 42.0 | 4.26e-01 | 96.5% | 100.0% |
D7
medium
residues 769-844