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HSP70h

Euk-Vir

Blackcurrant_leafroll-associated_virus_1

HSP70h__YP_009553662__Blackcurrant_leafroll-associated_virus_1__2292426

Identity

Accession:: YP_009553662 ↗
Protein ID:: HSP70h
Kingdom:: euk

Quality

84.5 mean pLDDT

Taxonomy

Orthornavirae› Kitrinoviricota› Alsuviricetes› Martellivirales› Closteroviridae› Closterovirus› Blackcurrant_leafroll-associated_virus_1

TaxID: 2292426

Cluster

View cluster (42 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 381-488

PDB

Domain cluster: rep: heat_shock_protein_70_homolog__YP_009241368__Grapevine_leafroll-associated_virus_13__1815581__D381-469

D2 high residues 506-588

PDB

Domain cluster: representative

CATH (14)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
2es9A00	1.20.1290.30	Mainly Alpha › Up-down Bundle › AhpD-like ›	0.58	40.0	3.77e-01	71.1%	99.0%
7jveC01	3.40.30.10	Alpha Beta › 3-Layer(aba) Sandwich › Glutaredoxin › Glutaredoxin	0.57	45.0	3.34e-01	88.0%	33.1%
4c0nA00	1.10.490.10	Mainly Alpha › Orthogonal Bundle › Globin-like › Globins	0.57	49.0	4.15e-01	98.8%	66.0%
8dtqA01	1.10.260.40	Mainly Alpha › Orthogonal Bundle › 434 Repressor (Amino-terminal Domain) › lambda repressor-like DNA-binding domains	0.57	47.0	4.77e-01	94.0%	98.8%
4nv0A02	1.10.150.340	Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Pyrimidine 5'-nucleotidase (UMPH-1), N-terminal domain	0.55	40.0	4.02e-01	75.9%	92.7%
1aluA00	1.20.1250.10	Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; ›	0.54	39.0	3.15e-01	74.7%	62.4%
3hhcC00	1.20.1250.60	Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › Interferon lambda	0.54	40.0	3.32e-01	78.3%	53.6%
1b0bA00	1.10.490.10	Mainly Alpha › Orthogonal Bundle › Globin-like › Globins	0.54	45.0	3.85e-01	94.0%	73.8%
3ivpD01	1.10.260.40	Mainly Alpha › Orthogonal Bundle › 434 Repressor (Amino-terminal Domain) › lambda repressor-like DNA-binding domains	0.53	39.0	4.06e-01	79.5%	92.0%
1v5kA00	1.10.418.10	Mainly Alpha › Orthogonal Bundle › Actin-binding Protein, T-fimbrin; domain 1 › Calponin-like domain	0.53	38.0	3.45e-01	75.9%	67.0%
4hfkB00	1.20.120.1620	Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) ›	0.53	44.0	4.19e-01	92.8%	91.8%
3h4cA01	1.10.472.10	Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like	0.52	36.0	3.49e-01	73.5%	80.2%
3fvvA02	1.20.1440.100	Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › SG protein - dephosphorylation function	0.52	41.0	4.30e-01	90.4%	100.0%
2of5H00	1.10.533.10	Mainly Alpha › Orthogonal Bundle › Death Domain, Fas › Death Domain, Fas	0.51	42.0	3.99e-01	91.6%	97.0%

ECOD (9)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
4936137	7000.1.1.0 ↗	alpha arrays › inserted region in the C-terminal domain of the archeal LeuRS › inserted region in the C-terminal domain of the archeal LeuRS › inserted region in the C-terminal domain of the archeal LeuRS	0.70	33.0	3.70e-01	95.2%	56.9%
3925230	2003.1.5.65 ↗	a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › DOT1	0.66	58.0	3.90e-01	100.0%	66.8%
4881917	2485.1.1.41 ↗	a+b three layers › Thioredoxin-like › Thioredoxin-like › Thioredoxin-like › Thioredoxin_4	0.64	50.0	4.21e-01	86.7%	79.2%
4932388	101.1.6.0 ↗	alpha arrays › HTH › HTH › TrpR	0.62	34.0	3.55e-01	98.8%	57.3%
3730771	4953.1.1.2 ↗	beta barrels › L-aspartase C-terminal domain-like › L-aspartase C-terminal domain-like › L-aspartase C-terminal domain-like › ADSL_C	0.58	43.0	4.34e-01	83.1%	91.8%
4203629	4044.1.1.1 ↗	alpha bundles › Helical bundle domain in prismane-like proteins › Helical bundle domain in prismane-like proteins › Helical bundle domain in prismane-like proteins › Prismane	0.57	50.0	4.61e-01	97.6%	97.3%
3955662	316.1.1.0 ↗	a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase	0.56	38.0	3.04e-01	71.1%	51.1%
4301068	194.1.1.1 ↗	alpha complex topology › Serum albumin-like › Serum albumin-like › Serum albumin-like › Serum_albumin	0.52	41.0	3.25e-01	90.4%	80.0%
3861565	150.3.1.1 ↗	alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › 4-helical cytokines › 4-helical cytokine › Hormone_1	0.51	36.0	2.76e-01	74.7%	54.0%

D3 medium residues 1-33_128-190_351-373

PDB

Domain cluster: rep: heat-shock_protein__NP_619695__Lettuce_infectious_yellows_virus__31713__D2-172

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF00012.27 best	HSP70	35.2	6.20e-09	56.3%	9.2%

D4 medium residues 34-127

PDB

Domain cluster: rep: Hsp70h__YP_009162624__Tobacco_virus_1__1692045__D36-122

CATH (12)

Domain ID	Class ID	Classification	TM-score	Bits	E-value	Q cov	T cov
1dbzA01	3.30.540.10	Alpha Beta › 2-Layer Sandwich › Fructose-1,6-Bisphosphatase; Chain A, domain 1 › Fructose-1,6-Bisphosphatase, subunit A, domain 1	0.61	48.0	3.93e-01	86.2%	96.2%
1b24A01	3.10.28.10	Alpha Beta › Roll › Endonuclease I-creI › Homing endonucleases	0.57	38.0	3.80e-01	81.9%	66.3%
2j0wA03	3.30.70.260	Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain	0.56	34.0	3.59e-01	83.0%	69.1%
4dzrA00	3.40.50.150	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39	0.56	42.0	3.57e-01	81.9%	79.8%
3evzA01	3.40.50.150	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39	0.54	40.0	3.40e-01	79.8%	89.8%
3gkuA03	3.30.1370.50	Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › R3H-like domain	0.54	31.0	3.50e-01	85.1%	74.6%
1totA00	3.30.60.90	Alpha Beta › 2-Layer Sandwich › Wheat Germ Agglutinin (Isolectin 2); domain 1 › Zinc finger, ZZ-type	0.53	24.0	3.00e-01	81.9%	71.2%
2cpmA00	3.30.1370.50	Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › R3H-like domain	0.51	34.0	3.49e-01	89.4%	69.1%
2n8lA00	3.30.310.210	Alpha Beta › 2-Layer Sandwich › TATA-Binding Protein ›	0.51	43.0	3.52e-01	96.8%	78.5%
2q7eA02	3.30.930.10	Alpha Beta › 2-Layer Sandwich › BirA Bifunctional Protein; domain 2 › Bira Bifunctional Protein; Domain 2	0.51	39.0	3.10e-01	84.0%	84.9%
3qwuA03	3.30.70.2160	Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits ›	0.51	39.0	3.53e-01	85.1%	84.2%
2pv0A02	3.40.50.150	Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39	0.51	43.0	3.47e-01	98.9%	84.3%

ECOD (11)

UID	F-ID	Classification	TM-score	Bits	E-value	Q cov	T cov
4934172	242.1.1.7 ↗	a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases › LAGLIDADG_3	0.59	37.0	4.11e-01	83.0%	84.3%
3602142	242.1.1.7 ↗	a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases › LAGLIDADG_3	0.59	39.0	3.79e-01	85.1%	60.0%
3602910	242.1.1.7 ↗	a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases › LAGLIDADG_3	0.59	36.0	3.75e-01	81.9%	64.4%
3173837	327.11.2.35 ↗	a+b two layers › Alpha-lytic protease prodomain-like › KH-domains › Eukaryotic type KH-domain (KH-domain type I) › PF29984	0.59	43.0	3.84e-01	79.8%	90.3%
3623603	320.1.1.0 ↗	a+b two layers › R3H domain-like › R3H domain › R3H domain	0.57	36.0	3.49e-01	85.1%	55.2%
None	—		0.55	39.0	3.05e-01	74.5%	70.0%
None	—		0.55	39.0	3.05e-01	74.5%	70.0%
4031808	320.1.1.3 ↗	a+b two layers › R3H domain-like › R3H domain › R3H domain › YlmH_1st	0.54	33.0	3.37e-01	87.2%	62.2%
2849954	320.2.1.1 ↗	a+b two layers › R3H domain-like › Ribosomal protein S8, N-terminal domain › Ribosomal protein S8, N-terminal domain › Ribosomal_S8	0.53	32.0	3.48e-01	84.0%	72.4%
5064595	219.1.1.13 ↗	a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Transglut_core	0.53	41.0	3.22e-01	85.1%	64.5%
5029251	242.1.1.0 ↗	a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases	0.51	36.0	3.82e-01	97.9%	83.5%

D5 medium residues 191-232_307-350

PDB

Domain cluster: rep: NC_005856.1__YP_006576.1__P1_gp110__00106__D281-382

Pfam (1)

Accession	Name	Score	E-value	Q cov	HMM cov
PF00012.27 best	HSP70	27.5	1.30e-06	57.0%	6.8%

D6 medium residues 233-306

PDB

Domain cluster: rep: p67__YP_003075968__Carrot_yellow_leaf_virus__656190__D231-307