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HSP90h
Euk-VirMalus_domestica_virus_A
HSP90h__YP_010087862__Malus_domestica_virus_A__2664236
Identity
- Accession:
- YP_010087862 ↗
- Protein ID:
- HSP90h
- Kingdom:
- euk
Quality
76.8
mean pLDDT
Taxonomy
Orthornavirae›
Kitrinoviricota›
Alsuviricetes›
Martellivirales›
Closteroviridae›
Velarivirus›
Malus_domestica_virus_A
TaxID: 2664236
Cluster
Singleton — not in a non-trivial cluster
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 3-129
D2
high
residues 198-326
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF03225.20 best | Viral_Hsp90 | 28.8 | 6.80e-07 | 97.7% | 21.9% |
CATH (6)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1zbtA01 | 6.10.140.1950 | Special › Helix non-globular › Helix Hairpins › | 0.56 | 23.0 | 2.82e-01 | 73.6% | 55.4% |
| 3hd6A00 | 1.10.3430.10 | Mainly Alpha › Orthogonal Bundle › Ammonium transporter fold › Ammonium transporter AmtB like domains | 0.55 | 46.0 | 3.28e-01 | 90.7% | 55.1% |
| 7c1iA01 | 1.20.120.160 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain | 0.55 | 32.0 | 3.52e-01 | 86.8% | 71.0% |
| 4irlB02 | 1.10.533.10 | Mainly Alpha › Orthogonal Bundle › Death Domain, Fas › Death Domain, Fas | 0.54 | 31.0 | 3.50e-01 | 77.5% | 75.3% |
| 3cucA00 | 1.10.3290.10 | Mainly Alpha › Orthogonal Bundle › Fic-like fold › Fido-like domain | 0.52 | 39.0 | 3.17e-01 | 79.8% | 61.1% |
| 3lqhA02 | 1.20.920.10 | Mainly Alpha › Up-down Bundle › Histone Acetyltransferase; Chain A › Bromodomain-like | 0.52 | 36.0 | 3.84e-01 | 76.7% | 85.8% |
ECOD (4)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3288129 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.52 | 36.0 | 3.26e-01 | 71.3% | 91.5% |
| 3655623 | 145.1.1.1 ↗ | alpha arrays › F-box domain › F-box domain › F-box domain › F-box | 0.52 | 29.0 | 3.10e-01 | 89.9% | 59.1% |
| 4017157 | 150.1.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin | 0.51 | 44.0 | 4.08e-01 | 95.3% | 92.1% |
| 3460830 | 604.16.1.3 ↗ | alpha bundles › Spectrin repeat-like › Hypothetical membrane protein Ta0354, soluble domain › Hypothetical membrane protein Ta0354, soluble domain › Vwaint | 0.50 | 30.0 | 3.32e-01 | 89.1% | 72.4% |
D3
high
residues 331-481
Domain cluster:
rep: Hsp90__YP_010086803__Pistachio_ampelovirus_A__2093224__D326-483
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF03225.20 best | Viral_Hsp90 | 92.9 | 2.50e-26 | 100.0% | 26.4% |
CATH (5)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1a31A03 | 3.90.15.10 | Alpha Beta › Alpha-Beta Complex › Topoisomerase I; Chain A, domain 3 › Topoisomerase I; Chain A, domain 3 | 0.56 | 36.0 | 3.69e-01 | 72.8% | 65.3% |
| 1aroP05 | 1.10.150.20 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › 5' to 3' exonuclease, C-terminal subdomain | 0.56 | 36.0 | 3.29e-01 | 87.4% | 46.4% |
| 1y96A00 | 2.30.30.100 | Mainly Beta › Roll › SH3 type barrels. › | 0.54 | 27.0 | 3.31e-01 | 70.9% | 76.7% |
| 2mh9A00 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.51 | 33.0 | 3.55e-01 | 90.1% | 76.4% |
| 1kyzA01 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.50 | 28.0 | 3.26e-01 | 93.4% | 76.7% |
ECOD (14)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3587631 | 186.1.1.0 ↗ | alpha arrays › lambda integrase-N-like › lambda integrase-N › lambda integrase-N | 0.56 | 38.0 | 3.98e-01 | 94.0% | 73.6% |
| 3326456 | 2484.1.1.2 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Actin | 0.55 | 50.0 | 3.72e-01 | 100.0% | 65.1% |
| 3704631 | 2484.1.1.2 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Actin | 0.54 | 49.0 | 3.68e-01 | 99.3% | 62.1% |
| 4647653 | 2484.1.1.1 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › HSP70 | 0.53 | 48.0 | 3.45e-01 | 97.4% | 93.9% |
| 3828165 | 2484.1.1.2 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Actin | 0.53 | 48.0 | 4.14e-01 | 100.0% | 85.0% |
| 3883105 | 3226.1.1.1 ↗ | alpha complex topology › Uracil Transporter UraA › Uracil Transporter UraA › Uracil Transporter UraA › Xan_ur_permease | 0.53 | 45.0 | 3.19e-01 | 93.4% | 88.6% |
| 3380586 | 2484.1.1.2 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Actin | 0.53 | 48.0 | 3.62e-01 | 98.7% | 88.6% |
| 4028937 | 109.4.1.1255 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Adaptin_N, Cnd1 | 0.53 | 31.0 | 1.99e-01 | 92.7% | 11.4% |
| 4199985 | 2484.1.1.2 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Actin | 0.52 | 46.0 | 3.68e-01 | 97.4% | 87.4% |
| 4539356 | 2484.1.1.1 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › HSP70 | 0.51 | 45.0 | 3.38e-01 | 96.0% | 94.6% |
| 4970053 | 3896.1.1.0 ↗ | alpha duplicates or obligate multimers › Intramembrane CDP-DAG synthetase-related › Intramembrane CDP-DAG synthetase-related › Intramembrane CDP-DAG synthetase | 0.51 | 34.0 | 3.02e-01 | 88.7% | 43.8% |
| 3409778 | 192.2.1.2 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › Prefoldin | 0.51 | 28.0 | 3.05e-01 | 77.5% | 62.3% |
| 3263845 | 2484.1.1.1 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › HSP70 | 0.51 | 45.0 | 3.12e-01 | 97.4% | 61.6% |
| 3255532 | 2484.1.1.1 ↗ | mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › HSP70 | 0.50 | 44.0 | 3.96e-01 | 94.0% | 82.4% |
D4
medium
residues 130-184