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HSPV002
Euk-VirHorsepox_virus
HSPV002__ABH08089__Horsepox_virus__397342
Identity
- Accession:
- ABH08089 ↗
- Protein ID:
- HSPV002
- Kingdom:
- euk
Quality
71.7
mean pLDDT
Taxonomy
Bamfordvirae›
Nucleocytoviricota›
Pokkesviricetes›
Chitovirales›
Poxviridae›
Orthopoxvirus›
Horsepox_virus
TaxID: 397342
Cluster
View cluster (92 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 39-246
Domain cluster:
rep: Viral_TNFR_II-like_c-terminal_fragment__YP_227393__Deerpox_virus_W-848-83__305674__D31-193
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF02250.21 best | Orthopox_35kD | 209.8 | 5.20e-62 | 100.0% | 86.5% |
CATH (18)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1cq3A00 | 2.60.240.10 | Mainly Beta › Sandwich › Viral Chemokine Inhibitor; Chain A › Major secreted virus protein | 0.84 | 81.0 | 7.91e-01 | 100.0% | 92.0% |
| 3on9A00 | 2.60.240.20 | Mainly Beta › Sandwich › Viral Chemokine Inhibitor; Chain A › | 0.79 | 57.0 | 6.51e-01 | 100.0% | 95.6% |
| 2vgaA00 | 2.60.240.10 | Mainly Beta › Sandwich › Viral Chemokine Inhibitor; Chain A › Major secreted virus protein | 0.73 | 63.0 | 6.53e-01 | 100.0% | 95.9% |
| 4bfeA02 | 2.60.40.10 | Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins | 0.69 | 26.0 | 4.06e-01 | 85.1% | 86.4% |
| 4kyzA00 | 3.30.70.600 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Ribosomal protein S10 | 0.65 | 29.0 | 3.22e-01 | 84.6% | 50.9% |
| 3ejjX03 | 2.60.40.10 | Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins | 0.65 | 27.0 | 3.80e-01 | 85.6% | 80.0% |
| 2od4B01 | 3.30.70.100 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.62 | 28.0 | 4.26e-01 | 80.3% | 100.0% |
| 3kg0A00 | 3.30.70.100 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.60 | 28.0 | 4.09e-01 | 83.2% | 94.8% |
| 1nbuA00 | 3.30.1130.10 | Alpha Beta › 2-Layer Sandwich › GTP Cyclohydrolase I, domain 2 › GTP cyclohydrolase I, C-terminal domain/NADPH-dependent 7-cyano-7-deazaguanine reductase, N-terminal domain | 0.59 | 28.0 | 3.67e-01 | 90.4% | 78.8% |
| 2cg8C01 | 3.30.1130.10 | Alpha Beta › 2-Layer Sandwich › GTP Cyclohydrolase I, domain 2 › GTP cyclohydrolase I, C-terminal domain/NADPH-dependent 7-cyano-7-deazaguanine reductase, N-terminal domain | 0.58 | 28.0 | 3.61e-01 | 90.4% | 79.0% |
| 1dhnA00 | 3.30.1130.10 | Alpha Beta › 2-Layer Sandwich › GTP Cyclohydrolase I, domain 2 › GTP cyclohydrolase I, C-terminal domain/NADPH-dependent 7-cyano-7-deazaguanine reductase, N-terminal domain | 0.58 | 28.0 | 3.62e-01 | 90.4% | 78.5% |
| 2q2eB05 | 2.60.40.2960 | Mainly Beta › Sandwich › Immunoglobulin-like › | 0.57 | 24.0 | 3.50e-01 | 74.0% | 85.7% |
| 5z0uA03 | 2.60.40.1180 | Mainly Beta › Sandwich › Immunoglobulin-like › Golgi alpha-mannosidase II | 0.56 | 21.0 | 3.10e-01 | 85.1% | 75.6% |
| 7xoiD01 | 2.60.40.1180 | Mainly Beta › Sandwich › Immunoglobulin-like › Golgi alpha-mannosidase II | 0.55 | 20.0 | 2.76e-01 | 92.3% | 60.7% |
| 2p4bB02 | 3.30.200.100 | Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › MucB/RseB, C-terminal domain | 0.54 | 26.0 | 3.76e-01 | 81.2% | 96.9% |
| 4q7aC02 | 3.30.70.360 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.54 | 29.0 | 3.91e-01 | 85.1% | 99.1% |
| 4jbjA01 | 2.40.50.140 | Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins | 0.54 | 24.0 | 3.21e-01 | 97.6% | 76.4% |
| 1yqfB00 | 3.10.280.10 | Alpha Beta › Roll › Mitochondrial Matrix Protein; Chain A › Mitochondrial glycoprotein | 0.51 | 25.0 | 2.75e-01 | 72.1% | 51.4% |
ECOD (16)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 161466 | 527.1.1.1 ↗ | beta sandwiches › Soluble secreted chemokine inhibitor, VCCI › Soluble secreted chemokine inhibitor, VCCI › Soluble secreted chemokine inhibitor, VCCI › Orthopox_35kD | 0.84 | 82.0 | 7.70e-01 | 100.0% | 89.7% |
| 4855718 | 527.1.1.1 ↗ | beta sandwiches › Soluble secreted chemokine inhibitor, VCCI › Soluble secreted chemokine inhibitor, VCCI › Soluble secreted chemokine inhibitor, VCCI › Orthopox_35kD | 0.73 | 63.0 | 6.55e-01 | 100.0% | 95.4% |
| 5083518 | 304.25.1.12 ↗ | a+b two layers › Alpha-beta plaits › Bacterial exopeptidase dimerisation domain › Bacterial exopeptidase dimerisation domain › Pcc1 | 0.65 | 28.0 | 4.38e-01 | 80.8% | 98.8% |
| 5189 | 304.4.1.0 ↗ | a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel | 0.62 | 29.0 | 4.12e-01 | 83.7% | 92.0% |
| 3602312 | 325.1.6.4 ↗ | a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Duplicated hybrid motif › PS_Dcarbxylase | 0.62 | 34.0 | 3.68e-01 | 96.6% | 62.9% |
| 1177762 | 230.1.1.4 ↗ | a+b two layers › T-fold › Tetrahydrobiopterin biosynthesis enzymes-like › Tetrahydrobiopterin biosynthesis enzymes-like › FolB | 0.60 | 28.0 | 3.69e-01 | 90.4% | 78.4% |
| 4677406 | 230.1.1.4 ↗ | a+b two layers › T-fold › Tetrahydrobiopterin biosynthesis enzymes-like › Tetrahydrobiopterin biosynthesis enzymes-like › FolB | 0.60 | 29.0 | 3.76e-01 | 90.4% | 78.2% |
| 3962326 | 230.1.1.0 ↗ | a+b two layers › T-fold › Tetrahydrobiopterin biosynthesis enzymes-like › Tetrahydrobiopterin biosynthesis enzymes-like | 0.58 | 28.0 | 3.65e-01 | 90.9% | 78.3% |
| 3375193 | 230.1.1.4 ↗ | a+b two layers › T-fold › Tetrahydrobiopterin biosynthesis enzymes-like › Tetrahydrobiopterin biosynthesis enzymes-like › FolB | 0.58 | 28.0 | 3.49e-01 | 90.9% | 73.1% |
| 4008120 | 5.1.5.139 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 8-bladed › DUF1481 | 0.57 | 29.0 | 3.72e-01 | 92.8% | 82.5% |
| 4980945 | 304.4.1.0 ↗ | a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel | 0.57 | 29.0 | 4.09e-01 | 84.1% | 99.0% |
| 3943581 | 881.4.1.1 ↗ | a+b three layers › Mog1p/PsbP-like › C-terminal domain in sigma-E factor regulatory protein rseB › C-terminal domain in sigma-E factor regulatory protein rseB › MucB_RseB_C | 0.56 | 27.0 | 3.61e-01 | 80.3% | 85.5% |
| 3608837 | 10.2.1.0 ↗ | beta sandwiches › jelly-roll › Nucleoplasmin-like/VP (viral coat and capsid proteins) › Nucleoplasmin-like/VP (viral coat and capsid proteins) | 0.55 | 29.0 | 3.28e-01 | 80.8% | 63.2% |
| 5074212 | 331.10.2.0 ↗ | a+b two layers › TBP-like › S-adenosylmethionine decarboxylase-related › Bacterial S-adenosylmethionine decarboxylase | 0.54 | 27.0 | 3.67e-01 | 85.6% | 90.9% |
| 3579137 | 243.3.1.18 ↗ | a+b two layers › Cystatin-like › Cystatin/monellin › Cystatin/monellin › NIDO | 0.53 | 25.0 | 3.43e-01 | 85.6% | 87.5% |
| 3921186 | 67.1.1.1 ↗ | beta sandwiches › HSP40/DnaJ peptide-binding domain › HSP40/DnaJ peptide-binding domain › HSP40/DnaJ peptide-binding domain › DnaJ_C | 0.50 | 27.0 | 3.25e-01 | 85.1% | 80.0% |