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HSPV178b

Euk-Vir

Horsepox_virus

HSPV178b__ABH08289__Horsepox_virus__397342

Identity

Accession:
ABH08289 ↗
Protein ID:
HSPV178b
Kingdom:
euk

Quality

71.1 mean pLDDT

Taxonomy

Bamfordvirae› Nucleocytoviricota› Pokkesviricetes› Chitovirales› Poxviridae› Orthopoxvirus› Horsepox_virus

TaxID: 397342

Cluster

Singleton — not in a non-trivial cluster

3D Structure

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Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 21-96
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00625.28 best Guanylate_kin 37.6 2.70e-09 90.8% 35.2%
CATH (35)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
6rxaA01 1.10.40.30 Mainly Alpha › Orthogonal Bundle › Ribonucleotide Reductase Protein R1; domain 1 › Fumarase/aspartase (C-terminal domain) 0.72 51.0 4.92e-01 96.1% 65.5%
1tj7A03 1.10.40.30 Mainly Alpha › Orthogonal Bundle › Ribonucleotide Reductase Protein R1; domain 1 › Fumarase/aspartase (C-terminal domain) 0.70 46.0 4.81e-01 93.4% 73.2%
1dcnA03 1.10.40.30 Mainly Alpha › Orthogonal Bundle › Ribonucleotide Reductase Protein R1; domain 1 › Fumarase/aspartase (C-terminal domain) 0.69 46.0 4.79e-01 94.7% 73.6%
2px0A01 1.20.120.1380 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Flagellar FlhF biosynthesis protein, N domain 0.67 45.0 4.62e-01 94.7% 72.6%
2l4eA00 1.10.8.10 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Ubiquitin-associated (UBA) domain 0.67 37.0 4.18e-01 92.1% 71.9%
2hoqA02 1.10.150.520 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › 0.65 43.0 4.29e-01 92.1% 64.6%
2l2dA00 1.10.8.10 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Ubiquitin-associated (UBA) domain 0.65 42.0 4.32e-01 98.7% 68.5%
2khmA01 1.10.10.1350 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Spidroin domain, C-terminal domain 0.64 43.0 3.81e-01 71.1% 49.1%
3mzvA00 1.10.600.10 Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase 0.61 53.0 3.58e-01 98.7% 24.9%
2j3tD01 3.30.450.70 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › 0.60 43.0 3.56e-01 75.0% 89.6%
3cjlA00 3.10.20.850 Alpha Beta › Roll › Ubiquitin-like (UB roll) › Protein of unknown function DUF3861 0.59 43.0 4.11e-01 90.8% 65.9%
1s8nA02 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.59 41.0 4.59e-01 78.9% 96.6%
8ctsB01 1.10.287.70 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.58 38.0 3.62e-01 85.5% 58.6%
4c2uA02 1.10.10.160 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › 0.57 36.0 3.56e-01 97.4% 59.3%
1wdhA02 1.10.720.60 Mainly Alpha › Orthogonal Bundle › Transcription Termination Factor Rho, Rna-binding Domain; Chain A, Domain 1 › 0.56 40.0 3.71e-01 76.3% 95.1%
1x42A02 1.10.150.240 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 0.56 42.0 4.09e-01 92.1% 73.5%
3bvxA02 1.20.1270.50 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Glycoside hydrolase family 38, central domain 0.56 42.0 3.74e-01 81.6% 71.2%
3vkgB04 1.10.8.710 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Dynein motor, AAA1 domain, small subdomain 0.56 46.0 4.00e-01 93.4% 96.7%
2i5uA00 1.10.10.630 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › DnaD domain-like 0.55 45.0 4.51e-01 90.8% 93.5%
4akgA06 1.10.8.710 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Dynein motor, AAA1 domain, small subdomain 0.55 45.0 4.12e-01 94.7% 94.4%
3w0lD01 1.10.8.1080 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › 0.54 41.0 3.77e-01 94.7% 62.4%
4g12A02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.54 44.0 3.54e-01 89.5% 85.9%
3nqxA02 1.10.390.10 Mainly Alpha › Orthogonal Bundle › Neutral Protease; domain 2 › Neutral Protease Domain 2 0.53 42.0 3.46e-01 100.0% 45.9%
3rosA01 3.40.605.10 Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 1 › Aldehyde Dehydrogenase; Chain A, domain 1 0.53 46.0 3.14e-01 96.1% 70.9%
4fm3A00 1.20.1270.390 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.53 41.0 3.81e-01 82.9% 68.4%
6xgzE01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.52 46.0 3.22e-01 100.0% 40.3%
1j8yF01 1.20.120.140 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › SRP54, nucleotide-binding domain 0.52 43.0 4.20e-01 100.0% 83.7%
3tmpA01 3.90.70.80 Alpha Beta › Alpha-Beta Complex › Cathepsin B; Chain A › 0.52 40.0 3.24e-01 84.2% 64.0%
1um8A01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.52 44.0 3.14e-01 94.7% 70.9%
3f2eA00 1.20.58.800 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.51 37.0 3.65e-01 93.4% 69.9%
1oj7A02 1.20.1090.10 Mainly Alpha › Up-down Bundle › Dehydroquinate synthase-like, alpha domain › Dehydroquinate synthase-like - alpha domain 0.51 42.0 3.12e-01 92.1% 61.3%
5ubvA02 1.10.8.60 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › 0.51 38.0 3.93e-01 93.4% 85.9%
3gfoA00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.51 45.0 3.13e-01 100.0% 40.2%
4cgyA04 1.10.290.10 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; domain 4 › Topoisomerase I, domain 4 0.50 42.0 3.69e-01 98.7% 72.8%
3ty4B00 3.40.718.10 Alpha Beta › 3-Layer(aba) Sandwich › Isopropylmalate Dehydrogenase › Isopropylmalate Dehydrogenase 0.50 42.0 2.80e-01 98.7% 84.0%
ECOD (33)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4991597 2006.1.1.1 ↗ a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like › Hydrolase 0.72 47.0 3.33e-01 92.1% 22.2%
5025739 4953.1.1.2 ↗ beta barrels › L-aspartase C-terminal domain-like › L-aspartase C-terminal domain-like › L-aspartase C-terminal domain-like › ADSL_C 0.62 47.0 4.74e-01 82.9% 81.3%
4972496 102.2.1.0 ↗ alpha arrays › HhH/H2TH › H2TH › H2TH 0.61 46.0 4.39e-01 88.2% 67.8%
5052392 102.1.3.0 ↗ alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › PAP/OAS1 substrate-binding domain 0.61 51.0 4.38e-01 92.1% 59.1%
4027697 109.4.1.0 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.60 41.0 3.24e-01 73.7% 33.8%
3706396 630.1.1.0 ↗ a+b complex topology › RuBisCo LSMT C-terminal, substrate-binding domain › RuBisCo LSMT C-terminal, substrate-binding domain › RuBisCo LSMT C-terminal, substrate-binding domain 0.58 50.0 3.97e-01 100.0% 55.9%
4998428 304.1.1.1 ↗ a+b two layers › Alpha-beta plaits › GHMP Kinase, C-terminal domain › GHMP Kinase, C-terminal domain › GHMP_kinases_C 0.58 40.0 3.36e-01 72.4% 50.4%
3840045 5054.1.1.0 ↗ alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels 0.57 38.0 3.83e-01 85.5% 66.3%
5048247 632.1.1.3 ↗ alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain › Alpha-mann_mid 0.57 45.0 4.14e-01 85.5% 76.0%
3891023 220.1.1.1 ↗ beta barrels › PH domain-like › PH domain-like › PH domain-like › PH 0.56 34.0 2.55e-01 90.8% 26.1%
4981781 5054.1.1.8 ↗ alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › Ion_trans_2 0.56 39.0 3.57e-01 80.3% 55.0%
1308538 632.1.1.3 ↗ alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain › Alpha-mann_mid 0.56 45.0 4.06e-01 88.2% 72.6%
3680449 142.1.1.22 ↗ alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors › SCAF11-like_C 0.56 49.0 4.60e-01 98.7% 85.1%
53647 632.1.1.0 ↗ alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain 0.56 42.0 3.73e-01 81.6% 71.2%
5079638 632.1.1.0 ↗ alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain 0.55 44.0 4.03e-01 86.8% 79.0%
3824733 142.1.1.0 ↗ alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors 0.54 47.0 4.53e-01 96.1% 88.2%
4881755 5054.1.1.8 ↗ alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › Ion_trans_2 0.53 40.0 3.63e-01 84.2% 60.0%
4032411 2004.1.1.5 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ABC_tran 0.53 47.0 3.25e-01 98.7% 40.4%
4095847 2004.1.1.5 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ABC_tran 0.53 44.0 3.10e-01 90.8% 30.6%
3178422 2004.1.1.0 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.53 46.0 2.71e-01 100.0% 15.0%
3318299 2004.1.1.0 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.53 47.0 3.07e-01 100.0% 32.2%
3366065 148.1.3.302 ↗ alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain › PRA1 0.52 41.0 3.66e-01 88.2% 63.5%
3213424 2004.1.1.5 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ABC_tran 0.52 46.0 3.10e-01 100.0% 35.1%
4846309 2004.1.1.7 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ABC_tran,BCA_ABC_TP_C 0.52 44.0 3.11e-01 94.7% 43.3%
4947390 7510.1.1.1 ↗ a/b three-layered sandwiches › Isocitrate/Isopropylmalate dehydrogenase-like › Isocitrate/Isopropylmalate dehydrogenase-like › Isocitrate/Isopropylmalate dehydrogenase-like › Iso_dh 0.52 41.0 3.21e-01 92.1% 72.1%
3717477 142.1.1.0 ↗ alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors 0.52 43.0 4.26e-01 92.1% 87.5%
3184513 3755.4.1.0 ↗ alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain 0.52 43.0 3.67e-01 96.1% 93.3%
3594224 2004.1.1.0 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.51 45.0 3.02e-01 98.7% 33.7%
5059378 2004.1.1.5 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ABC_tran 0.51 46.0 3.20e-01 100.0% 40.3%
3586839 2004.1.1.417 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ABC_tran, AAA_21 0.51 45.0 3.19e-01 100.0% 39.2%
3556055 2004.1.1.0 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.51 45.0 2.96e-01 100.0% 32.1%
3676853 109.4.1.1865 ↗ alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › SAP 0.51 33.0 1.97e-01 76.3% 9.5%
4942757 606.1.1.1 ↗ alpha complex topology › Nop N-terminal domain › Nop N-terminal domain › Nop N-terminal domain › Nop 0.50 35.0 3.23e-01 75.0% 62.9%