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HSPV185
Euk-VirHorsepox_virus
HSPV185__ABH08298__Horsepox_virus__397342
Identity
- Accession:
- ABH08298 ↗
- Protein ID:
- HSPV185
- Kingdom:
- euk
Quality
75.2
mean pLDDT
Taxonomy
Bamfordvirae›
Nucleocytoviricota›
Pokkesviricetes›
Chitovirales›
Poxviridae›
Orthopoxvirus›
Horsepox_virus
TaxID: 397342
Cluster
View cluster (14 members)3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 19-98
Domain cluster:
rep: soluble_interferon_gamma_receptor_B8__YP_009329625__BeAn_58058_virus__67082__D21-98
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF22325.3 best | CR4_N | 162.2 | 3.60e-48 | 100.0% | 100.0% |
D2
high
residues 106-208
Domain cluster:
rep: soluble_interferon-gamma_receptor-like_protein__YP_009408363__Murmansk_poxvirus__2025359__D104-203
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF07140.18 best | IFNGR1_D2 | 66.4 | 3.30e-18 | 100.0% | 95.4% |
D3
high
residues 223-270
Domain cluster:
representative
CATH (44)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3besR03 | 6.10.140.1480 | Special › Helix non-globular › Helix Hairpins › | 0.97 | 86.0 | 8.06e-01 | 93.8% | 80.4% |
| 2j5iA02 | 6.10.250.2850 | Special › Helix non-globular › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › | 0.86 | 64.0 | 6.96e-01 | 79.2% | 100.0% |
| 4nooB00 | 1.10.8.1160 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › | 0.82 | 73.0 | 5.82e-01 | 100.0% | 60.0% |
| 3vm9A02 | 6.10.140.2110 | Special › Helix non-globular › Helix Hairpins › | 0.82 | 70.0 | 6.63e-01 | 95.8% | 93.0% |
| 3bvoA02 | 1.20.1280.20 | Mainly Alpha › Up-down Bundle › Monooxygenase › HscB, C-terminal domain | 0.82 | 58.0 | 4.72e-01 | 75.0% | 44.2% |
| 2f93B00 | 1.10.287.470 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.81 | 67.0 | 6.61e-01 | 100.0% | 86.3% |
| 2ig3A00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.81 | 71.0 | 5.15e-01 | 100.0% | 37.0% |
| 4kp3C00 | 1.20.58.1770 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.80 | 71.0 | 5.95e-01 | 100.0% | 60.5% |
| 1tmxB00 | 2.60.130.10 | Mainly Beta › Sandwich › Protocatechuate 3,4-Dioxygenase, subunit A › Aromatic compound dioxygenase | 0.80 | 66.0 | 4.02e-01 | 91.7% | 15.3% |
| 2debB02 | 3.30.559.10 | Alpha Beta › 2-Layer Sandwich › Chloramphenicol Acetyltransferase › Chloramphenicol acetyltransferase-like domain | 0.79 | 67.0 | 4.06e-01 | 93.8% | 16.4% |
| 2m6uA00 | 1.20.81.20 | Mainly Alpha › Up-down Bundle › Receptor-associated Protein › | 0.78 | 61.0 | 5.22e-01 | 89.6% | 53.7% |
| 4dciA00 | 6.10.140.1110 | Special › Helix non-globular › Helix Hairpins › | 0.78 | 68.0 | 4.82e-01 | 100.0% | 34.7% |
| 4hzuS00 | 1.10.1760.20 | Mainly Alpha › Orthogonal Bundle › Arp2/3 complex 21 kDa subunit ARPC3 › | 0.77 | 65.0 | 4.56e-01 | 100.0% | 41.5% |
| 4jvtA02 | 1.10.12.10 | Mainly Alpha › Orthogonal Bundle › Lyase 2-enoyl-coa Hydratase; Chain A, domain 2 › Lyase 2-enoyl-coa Hydratase, Chain A, domain 2 | 0.77 | 58.0 | 6.10e-01 | 87.5% | 100.0% |
| 1xl7A01 | 1.10.275.20 | Mainly Alpha › Orthogonal Bundle › Fumarase C; Chain B, domain 1 › Choline/Carnitine o-acyltransferase | 0.76 | 64.0 | 4.97e-01 | 93.8% | 45.6% |
| 1tjlA00 | 1.20.120.910 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › DksA, coiled-coil domain | 0.76 | 69.0 | 4.80e-01 | 100.0% | 35.9% |
| 2cazC00 | 1.10.287.660 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.76 | 59.0 | 5.37e-01 | 100.0% | 64.1% |
| 1cxzB00 | 1.10.287.160 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat | 0.76 | 66.0 | 5.43e-01 | 97.9% | 65.1% |
| 4di1C02 | 1.10.12.10 | Mainly Alpha › Orthogonal Bundle › Lyase 2-enoyl-coa Hydratase; Chain A, domain 2 › Lyase 2-enoyl-coa Hydratase, Chain A, domain 2 | 0.76 | 57.0 | 5.97e-01 | 89.6% | 100.0% |
| 4l0rB00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.76 | 66.0 | 5.60e-01 | 95.8% | 61.6% |
| 3icxA01 | 1.10.287.660 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.75 | 66.0 | 5.73e-01 | 100.0% | 88.0% |
| 4jylA02 | 1.10.12.10 | Mainly Alpha › Orthogonal Bundle › Lyase 2-enoyl-coa Hydratase; Chain A, domain 2 › Lyase 2-enoyl-coa Hydratase, Chain A, domain 2 | 0.75 | 57.0 | 5.74e-01 | 87.5% | 83.7% |
| 3hpcX00 | 3.30.1520.10 | Alpha Beta › 2-Layer Sandwich › PX Domain › Phox-like domain | 0.74 | 63.0 | 4.49e-01 | 100.0% | 66.5% |
| 1lrzA03 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.74 | 65.0 | 5.98e-01 | 97.9% | 83.9% |
| 2ic6A00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.74 | 67.0 | 5.81e-01 | 100.0% | 91.5% |
| 5kjpA02 | 1.10.12.10 | Mainly Alpha › Orthogonal Bundle › Lyase 2-enoyl-coa Hydratase; Chain A, domain 2 › Lyase 2-enoyl-coa Hydratase, Chain A, domain 2 | 0.74 | 56.0 | 5.35e-01 | 85.4% | 100.0% |
| 4fzwA02 | 1.10.12.10 | Mainly Alpha › Orthogonal Bundle › Lyase 2-enoyl-coa Hydratase; Chain A, domain 2 › Lyase 2-enoyl-coa Hydratase, Chain A, domain 2 | 0.74 | 61.0 | 5.80e-01 | 93.8% | 96.6% |
| 2rdcA00 | 1.10.287.800 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › protein ne1242 | 0.74 | 64.0 | 4.67e-01 | 100.0% | 39.1% |
| 3zgxA02 | 6.10.140.1720 | Special › Helix non-globular › Helix Hairpins › | 0.74 | 64.0 | 5.24e-01 | 100.0% | 80.2% |
| 2gtsA00 | 1.10.287.850 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain | 0.73 | 64.0 | 5.44e-01 | 100.0% | 61.0% |
| 5z7rA02 | 1.10.12.10 | Mainly Alpha › Orthogonal Bundle › Lyase 2-enoyl-coa Hydratase; Chain A, domain 2 › Lyase 2-enoyl-coa Hydratase, Chain A, domain 2 | 0.73 | 55.0 | 5.47e-01 | 87.5% | 78.8% |
| 2yqyA00 | 1.20.120.450 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › dinb family like domain | 0.71 | 58.0 | 4.22e-01 | 89.6% | 38.9% |
| 1wtyA00 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.70 | 60.0 | 4.52e-01 | 97.9% | 39.7% |
| 1n1cA02 | 1.20.1280.20 | Mainly Alpha › Up-down Bundle › Monooxygenase › HscB, C-terminal domain | 0.70 | 57.0 | 4.91e-01 | 95.8% | 61.0% |
| 3eslA01 | 1.20.58.2070 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.69 | 58.0 | 5.02e-01 | 93.8% | 60.0% |
| 1hr5A00 | 1.20.5.420 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C | 0.69 | 55.0 | 5.52e-01 | 87.5% | 93.8% |
| 1jxzC02 | 1.10.12.10 | Mainly Alpha › Orthogonal Bundle › Lyase 2-enoyl-coa Hydratase; Chain A, domain 2 › Lyase 2-enoyl-coa Hydratase, Chain A, domain 2 | 0.68 | 50.0 | 4.77e-01 | 87.5% | 66.7% |
| 1dciA02 | 1.10.12.10 | Mainly Alpha › Orthogonal Bundle › Lyase 2-enoyl-coa Hydratase; Chain A, domain 2 › Lyase 2-enoyl-coa Hydratase, Chain A, domain 2 | 0.68 | 55.0 | 5.11e-01 | 93.8% | 93.7% |
| 4qfeK02 | 1.10.287.2460 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.68 | 45.0 | 4.76e-01 | 70.8% | 100.0% |
| 3k2nA00 | 3.30.450.40 | Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › GAF domain | 0.67 | 58.0 | 3.95e-01 | 100.0% | 74.0% |
| 1eg3A02 | 6.10.140.70 | Special › Helix non-globular › Helix Hairpins › | 0.66 | 45.0 | 4.57e-01 | 72.9% | 71.4% |
| 3qkaE02 | 1.10.287.2460 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.63 | 46.0 | 4.71e-01 | 87.5% | 93.0% |
| 1dk8A02 | 1.10.167.10 | Mainly Alpha › Orthogonal Bundle › Regulator of G-protein Signalling 4; domain 2 › Regulator of G-protein Signalling 4, domain 2 | 0.59 | 48.0 | 4.09e-01 | 95.8% | 52.9% |
| 2x1lB02 | 2.170.220.10 | Mainly Beta › Beta Complex › Methionyl-trna Synthetase; domain 2 › | 0.55 | 37.0 | 3.36e-01 | 85.4% | 47.4% |
ECOD (30)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 197868 | 614.1.1.0 ↗ | alpha duplicates or obligate multimers › L27 domain › L27 domain › L27 domain | 0.97 | 86.0 | 8.39e-01 | 93.8% | 88.2% |
| 3879791 | 378.1.1.0 ↗ | few secondary structure elements › His-Me finger endonucleases › His-Me finger endonucleases › His-Me finger endonucleases | 0.91 | 82.0 | 5.18e-01 | 100.0% | 21.8% |
| 3583325 | 4082.1.1.0 ↗ | alpha duplicates or obligate multimers › Hairy Orange domain › Hairy Orange domain › Hairy Orange domain | 0.90 | 82.0 | 7.35e-01 | 100.0% | 73.8% |
| 3535165 | 7023.1.1.0 ↗ | alpha bundles › helical ridge domain of D-alanyl transfer protein › helical ridge domain of D-alanyl transfer protein › helical ridge domain of D-alanyl transfer protein | 0.87 | 76.0 | 5.59e-01 | 97.9% | 40.0% |
| 3477975 | 7023.1.1.0 ↗ | alpha bundles › helical ridge domain of D-alanyl transfer protein › helical ridge domain of D-alanyl transfer protein › helical ridge domain of D-alanyl transfer protein | 0.86 | 74.0 | 5.52e-01 | 95.8% | 41.7% |
| 3563871 | 603.1.1.121 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › PF30821 | 0.85 | 74.0 | 5.57e-01 | 100.0% | 42.6% |
| 3653641 | 10.12.1.3 ↗ | beta sandwiches › jelly-roll › Double-stranded beta-helix › Double-stranded beta-helix › Cupin_1 | 0.83 | 68.0 | 4.19e-01 | 91.7% | 16.3% |
| 4323124 | 109.3.1.2 ↗ | alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › Ank,Ank_2 | 0.83 | 71.0 | 4.27e-01 | 97.9% | 14.5% |
| 4666568 | 109.3.1.2 ↗ | alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › Ank,Ank_2 | 0.83 | 71.0 | 4.21e-01 | 97.9% | 13.4% |
| 3626992 | 632.8.1.2 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › alpha-2-Macroglobulin receptor associated protein (RAP) domain 1 › alpha-2-Macroglobulin receptor associated protein (RAP) domain 1 › Alpha-2-MRAP_C | 0.82 | 69.0 | 5.36e-01 | 95.8% | 44.8% |
| 5072135 | 2498.1.1.10 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M48 | 0.82 | 72.0 | 4.76e-01 | 100.0% | 26.2% |
| 3236471 | 5054.1.1.8 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › Ion_trans_2 | 0.82 | 71.0 | 4.39e-01 | 100.0% | 31.1% |
| 3620869 | 101.1.9.106 ↗ | alpha arrays › HTH › HTH › Putative DNA-binding domain › Ion_trans | 0.81 | 69.0 | 5.52e-01 | 100.0% | 48.4% |
| 3186617 | 2004.1.1.30 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Helicase_C | 0.81 | 69.0 | 4.19e-01 | 100.0% | 14.9% |
| 3244309 | 5054.1.1.0 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels | 0.80 | 64.0 | 4.01e-01 | 89.6% | 17.6% |
| 4942548 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.80 | 70.0 | 4.87e-01 | 97.9% | 32.0% |
| 3220837 | 397.7.1.0 ↗ | few secondary structure elements › Toxic hairpin › Ribosome-inactivating protein luffin P1 › Ribosome-inactivating protein luffin P1 | 0.79 | 60.0 | 6.48e-01 | 83.3% | 97.5% |
| 3354521 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.79 | 69.0 | 5.86e-01 | 100.0% | 60.0% |
| 3623989 | 323.1.1.6 ↗ | a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › Carn_acyltransf | 0.79 | 67.0 | 4.65e-01 | 93.8% | 29.9% |
| 3708341 | 323.1.1.6 ↗ | a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › Carn_acyltransf | 0.78 | 66.0 | 3.83e-01 | 93.8% | 11.3% |
| 3770340 | 5041.1.1.2 ↗ | extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › TMEM169 | 0.77 | 65.0 | 5.15e-01 | 100.0% | 53.3% |
| 3897959 | 198.1.1.8 ↗ | alpha arrays › Saposin-like › Saposin-like › Saposin-like › SapA+SapB_2+SapB_1 | 0.76 | 57.0 | 4.30e-01 | 83.3% | 33.9% |
| 3261605 | 198.1.1.2 ↗ | alpha arrays › Saposin-like › Saposin-like › Saposin-like › SapB_2,SapB_1 | 0.75 | 62.0 | 5.22e-01 | 91.7% | 55.0% |
| 3585439 | 5054.1.1.8 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › Ion_trans_2 | 0.74 | 65.0 | 4.10e-01 | 100.0% | 42.0% |
| 3613914 | 3922.1.1.0 ↗ | alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 | 0.72 | 64.0 | 5.51e-01 | 100.0% | 69.3% |
| 4600409 | 507.1.1.0 ↗ | alpha arrays › DnaB helicase N-terminal domain-related › DnaB helicase N-terminal domain-related › DnaB helicase N-terminal domain-related | 0.71 | 64.0 | 4.56e-01 | 100.0% | 37.8% |
| 4957365 | 5069.1.3.0 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits | 0.70 | 62.0 | 4.76e-01 | 100.0% | 47.3% |
| 3486248 | 6132.1.1.0 ↗ | alpha bundles › Nudix hydrolase N-terminal dimerization domain › Nudix hydrolase N-terminal dimerization domain › Nudix hydrolase N-terminal dimerization domain | 0.69 | 56.0 | 5.07e-01 | 89.6% | 67.7% |
| 3512231 | 103.1.1.0 ↗ | alpha arrays › RuvA-C › RuvA-C, UBA, CRAL/TRIO-N, HBS1 › UBA-like domain | 0.66 | 44.0 | 4.67e-01 | 81.2% | 100.0% |
| 4024235 | 2004.1.1.14 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › GTP_EFTU | 0.63 | 50.0 | 3.14e-01 | 93.8% | 15.4% |