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HSPV194
Euk-VirHorsepox_virus
HSPV194__ABH08307__Horsepox_virus__397342
Identity
- Accession:
- ABH08307 ↗
- Protein ID:
- HSPV194
- Kingdom:
- euk
Quality
85.1
mean pLDDT
Taxonomy
Bamfordvirae›
Nucleocytoviricota›
Pokkesviricetes›
Chitovirales›
Poxviridae›
Orthopoxvirus›
Horsepox_virus
TaxID: 397342
Cluster
Singleton — not in a non-trivial cluster
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
medium
residues 16-124
Domain cluster:
rep: Ankyrin__YP_009143502__Raccoonpox_virus__10256__D1-135
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00023.37 best | Ank | 20.8 | 5.20e-04 | 32.1% | 90.9% |
D2
medium
residues 125-308
Domain cluster:
rep: MN180249.1__QHJ75400.1__X__00002__D85-208
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF13637.13 best | Ank_4 | 23.7 | 6.50e-05 | 26.1% | 78.0% |
D3
medium
residues 309-461
Domain cluster:
rep: hypothetical_protein_VARVgp187__NP_042231__Variola_virus__10255__D321-452
Pfam (2)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00023.37 best | Ank | 25.5 | 1.60e-05 | 21.6% | 93.9% |
| PF13606.13 | Ank_3 | 28.0 | 2.40e-06 | 19.6% | 96.8% |
D4
medium
residues 462-517
Domain cluster:
rep: CPXV211_protein__NP_619992__Cowpox_virus__10243__D445-520
D5
medium
residues 518-574
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF09372.16 best | PRANC | 39.2 | 1.00e-09 | 91.2% | 51.5% |
CATH (26)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3iylB02 | 1.10.2050.10 | Mainly Alpha › Orthogonal Bundle › Protein mu-1, chain B, domain 3 › Protein mu-1, chain B, domain 3 | 0.65 | 53.0 | 4.08e-01 | 91.2% | 50.7% |
| 1aabA00 | 1.10.30.10 | Mainly Alpha › Orthogonal Bundle › DNA Binding (I), subunit A › High mobility group box domain | 0.65 | 46.0 | 4.13e-01 | 82.5% | 53.0% |
| 2w9zA01 | 1.10.472.10 | Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like | 0.64 | 56.0 | 4.26e-01 | 98.2% | 67.7% |
| 4bxoA02 | 1.10.150.20 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › 5' to 3' exonuclease, C-terminal subdomain | 0.64 | 36.0 | 3.48e-01 | 75.4% | 46.3% |
| 2lwxA00 | 1.10.8.840 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Ribosome-associated complex head domain | 0.62 | 51.0 | 4.54e-01 | 96.5% | 64.8% |
| 2ebiA01 | 1.10.10.60 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like | 0.62 | 42.0 | 4.06e-01 | 80.7% | 62.1% |
| 3nb0B03 | 6.10.260.10 | Special › Helix non-globular › F1FO ATP Synthase › | 0.61 | 41.0 | 3.75e-01 | 77.2% | 48.8% |
| 3vuqB00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.61 | 44.0 | 3.21e-01 | 78.9% | 25.0% |
| 3b5iA02 | 1.10.1200.220 | Mainly Alpha › Orthogonal Bundle › Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A › | 0.61 | 47.0 | 4.12e-01 | 89.5% | 56.8% |
| 4c5fA02 | 1.10.530.10 | Mainly Alpha › Orthogonal Bundle › Lysozyme › | 0.60 | 51.0 | 3.74e-01 | 98.2% | 80.4% |
| 3ph0C00 | 1.25.40.1040 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.60 | 34.0 | 3.56e-01 | 70.2% | 58.5% |
| 3cdlA01 | 1.10.10.60 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like | 0.60 | 39.0 | 3.99e-01 | 73.7% | 70.4% |
| 3icxA01 | 1.10.287.660 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.59 | 40.0 | 3.69e-01 | 70.2% | 90.7% |
| 6xxvC00 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.59 | 42.0 | 3.43e-01 | 75.4% | 43.2% |
| 1b8dA00 | 1.10.490.20 | Mainly Alpha › Orthogonal Bundle › Globin-like › Phycocyanins | 0.59 | 49.0 | 3.65e-01 | 100.0% | 71.3% |
| 1uurA03 | 1.10.238.10 | Mainly Alpha › Orthogonal Bundle › Recoverin; domain 1 › EF-hand | 0.56 | 39.0 | 3.53e-01 | 77.2% | 60.2% |
| 5gp9A01 | 1.10.10.60 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like | 0.56 | 34.0 | 3.60e-01 | 71.9% | 70.8% |
| 3h0dB02 | 1.10.1200.150 | Mainly Alpha › Orthogonal Bundle › Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A › Transcriptional repressor of class III stress genes, C-terminal domain | 0.55 | 39.0 | 3.61e-01 | 78.9% | 64.2% |
| 4nphA02 | 1.20.1270.330 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.55 | 37.0 | 3.43e-01 | 70.2% | 98.6% |
| 1v9mA03 | 1.20.1690.10 | Mainly Alpha › Up-down Bundle › V-type ATP synthase subunit C fold › V-type ATP synthase subunit C domain | 0.55 | 38.0 | 3.31e-01 | 73.7% | 90.6% |
| 2a3qA00 | 1.10.287.1080 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › MazG-like | 0.54 | 37.0 | 3.03e-01 | 71.9% | 61.9% |
| 3fyaB00 | 1.10.260.40 | Mainly Alpha › Orthogonal Bundle › 434 Repressor (Amino-terminal Domain) › lambda repressor-like DNA-binding domains | 0.53 | 44.0 | 4.03e-01 | 94.7% | 81.8% |
| 1c9bA01 | 1.10.472.10 | Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like | 0.53 | 43.0 | 3.76e-01 | 98.2% | 79.4% |
| 6ncrA02 | 1.10.240.10 | Mainly Alpha › Orthogonal Bundle › Tyrosyl-Transfer RNA Synthetase › Tyrosyl-Transfer RNA Synthetase | 0.52 | 37.0 | 3.12e-01 | 78.9% | 65.7% |
| 2w02B01 | 1.10.150.640 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › AcsD, thumb domain, helical bundle | 0.51 | 39.0 | 3.59e-01 | 84.2% | 86.5% |
| 2xseA00 | 1.20.120.1440 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › JBP1, DNA-binding domain | 0.50 | 40.0 | 3.04e-01 | 94.7% | 41.5% |
ECOD (16)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3479759 | 101.1.1.0 ↗ | alpha arrays › HTH › HTH › Three-helical HTH | 0.66 | 47.0 | 4.37e-01 | 78.9% | 58.7% |
| 3959862 | 191.1.1.0 ↗ | alpha bundles › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain | 0.64 | 47.0 | 3.74e-01 | 80.7% | 38.3% |
| 3618598 | 219.1.1.0 ↗ | a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases | 0.61 | 52.0 | 4.14e-01 | 100.0% | 82.4% |
| 3927398 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.60 | 44.0 | 3.79e-01 | 84.2% | 51.4% |
| 4116362 | 632.7.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain | 0.60 | 52.0 | 4.69e-01 | 98.2% | 85.0% |
| 3229793 | 198.1.1.0 ↗ | alpha arrays › Saposin-like › Saposin-like › Saposin-like | 0.59 | 42.0 | 3.80e-01 | 78.9% | 55.3% |
| 3195747 | 3788.1.1.0 ↗ | alpha bundles › Viral accessory protein x (Vpx) / viral protein r (Vpr) › Viral accessory protein x (Vpx) / viral protein r (Vpr) › Viral accessory protein x (Vpx) / viral protein r (Vpr) | 0.58 | 40.0 | 3.89e-01 | 77.2% | 68.6% |
| 3284022 | 106.1.1.1 ↗ | alpha arrays › Globin-like › Globin-like › Globin-like › Globin | 0.58 | 47.0 | 3.49e-01 | 94.7% | 68.8% |
| 5018716 | 150.5.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like | 0.57 | 38.0 | 3.65e-01 | 70.2% | 67.1% |
| 4596646 | 7579.1.1.10 ↗ | a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases › Thioesterase | 0.57 | 50.0 | 3.29e-01 | 100.0% | 45.5% |
| 4412399 | 306.7.1.1 ↗ | a+b two layers › Glucose permease domain IIB-like › Trigger factor ribosome-binding domain › Trigger factor ribosome-binding domain › Trigger_N | 0.57 | 46.0 | 3.66e-01 | 89.5% | 44.3% |
| 5027220 | 5041.1.1.0 ↗ | extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C | 0.56 | 37.0 | 3.71e-01 | 75.4% | 66.7% |
| 3243267 | 5001.1.1.60 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Srx | 0.55 | 45.0 | 2.91e-01 | 93.0% | 31.5% |
| 4329038 | 375.1.9.15 ↗ | few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Zinc-nucleated domain of serine integrase › Insulin | 0.54 | 44.0 | 3.89e-01 | 93.0% | 86.7% |
| 4014878 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.54 | 42.0 | 2.64e-01 | 86.0% | 15.5% |
| 3286369 | 101.1.2.136 ↗ | alpha arrays › HTH › HTH › winged helix domain › HTH_20 | 0.54 | 39.0 | 3.28e-01 | 77.2% | 47.5% |