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HSV_ICP18.5_homolog

Euk-Vir

Murid_betaherpesvirus_1

HSV_ICP18.5_homolog__YP_214068__Murid_betaherpesvirus_1__10366

Identity

Accession:
YP_214068 ↗
Protein ID:
HSV_ICP18.5_homolog
Kingdom:
euk

Quality

76.4 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 5-201
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF01366.24 best PRTP 253.1 6.40e-75 99.5% 29.9%
CATH (12)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1nzeA00 1.20.120.290 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Oxygen-evolving enhancer protein 3 (PsbQ), four-helix up-down bundle 0.67 36.0 4.64e-01 87.3% 90.2%
3fnrA01 1.10.730.10 Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 0.66 31.0 3.58e-01 83.2% 58.6%
4w8pA02 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.65 39.0 4.59e-01 88.3% 86.9%
3ls1A00 1.20.120.290 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Oxygen-evolving enhancer protein 3 (PsbQ), four-helix up-down bundle 0.64 37.0 4.35e-01 88.3% 81.2%
6xz3A01 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.63 37.0 4.59e-01 85.8% 94.9%
1xzpA02 1.20.120.430 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › tRNA modification GTPase MnmE domain 2 0.58 40.0 4.38e-01 96.4% 83.1%
2v5cA03 1.20.58.460 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Hyaluronidase post-catalytic domain-like 0.58 35.0 4.18e-01 85.3% 90.0%
1xwjA01 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.55 33.0 3.91e-01 85.8% 86.9%
1gqeA01 1.20.58.410 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Release factor 0.55 31.0 3.95e-01 75.1% 93.8%
3uonA01 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.52 42.0 3.75e-01 85.3% 70.3%
2wb7A03 1.20.120.870 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › pT26-6p, five-helical bundle domain 0.51 33.0 3.88e-01 79.7% 94.1%
2gd5A00 6.10.140.1230 Special › Helix non-globular › Helix Hairpins › 0.51 29.0 3.36e-01 75.1% 76.1%
ECOD (16)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3435434 632.1.1.13 alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain › Rx_N 0.67 30.0 4.16e-01 74.6% 81.0%
3971025 601.4.1.0 alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains 0.66 39.0 4.73e-01 88.3% 90.4%
4124285 601.1.1.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.65 38.0 4.40e-01 88.3% 77.9%
4982260 5082.1.1.1 alpha bundles › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation_efflux 0.63 44.0 4.43e-01 70.1% 100.0%
5038958 5082.1.1.1 alpha bundles › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation_efflux 0.62 45.0 4.50e-01 74.6% 97.1%
3862625 601.1.1.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.62 36.0 4.21e-01 87.8% 80.0%
3466116 192.29.1.25 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › CA109-like 0.61 35.0 4.36e-01 88.8% 90.8%
3253934 601.1.1.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.61 37.0 4.56e-01 84.8% 96.7%
5032963 5069.1.1.0 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes 0.61 39.0 4.24e-01 88.8% 76.9%
3299078 1075.4.1.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › ABC_membrane 0.59 49.0 3.35e-01 86.8% 64.1%
3729299 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.58 40.0 4.48e-01 88.8% 89.7%
5021415 3579.1.1.33 extended segments › NADH-quinone oxidoreductase subunit J › NADH-quinone oxidoreductase subunit J › NADH-quinone oxidoreductase subunit J › PsiE 0.57 32.0 3.92e-01 76.6% 84.0%
4986123 3883.1.1.1 alpha bundles › CDP-alcohol phosphotransferase helical bundle domain › CDP-alcohol phosphotransferase helical bundle domain › CDP-alcohol phosphotransferase helical bundle domain › CDP-OH_P_transf 0.56 36.0 3.57e-01 85.3% 58.6%
3440913 4006.1.1.0 alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain 0.56 30.0 3.64e-01 75.1% 77.0%
5052077 5082.1.1.1 alpha bundles › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation_efflux 0.56 39.0 4.06e-01 70.6% 90.3%
4962483 5069.1.1.0 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes 0.55 40.0 3.95e-01 91.4% 70.2%
D2 medium residues 202-263
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF01366.24 best PRTP 45.2 5.40e-12 100.0% 7.8%
CATH (1)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3eoeD01 3.40.1380.20 Alpha Beta › 3-Layer(aba) Sandwich › Pyruvate Kinase; Chain: A, domain 1 › Pyruvate kinase, C-terminal domain 0.60 42.0 3.22e-01 77.4% 33.6%
D4 medium residues 569-678
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF01366.24 best PRTP 139.1 2.00e-40 83.6% 13.9%