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Hsp70h

Euk-Vir

Tobacco_virus_1

Hsp70h__YP_009162624__Tobacco_virus_1__1692045

Identity

Accession:
YP_009162624 ↗
Protein ID:
Hsp70h
Kingdom:
euk

Quality

83.6 mean pLDDT

Taxonomy

Orthornavirae› Kitrinoviricota› Alsuviricetes› Martellivirales› Closteroviridae› Closterovirus› Tobacco_virus_1

TaxID: 1692045

Cluster

View cluster (42 members)

3D Structure

Download PDB Download Scores JSON

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 231-360
PDB
Domain cluster: rep: HSP_70h__YP_762625__Strawberry_chlorotic_fleck-associated_virus__399314__D232-349
D2 high residues 393-502
PDB
Domain cluster: rep: heat_shock_protein_70_homolog__YP_009241368__Grapevine_leafroll-associated_virus_13__1815581__D381-469
D3 high residues 520-602
PDB
Domain cluster: representative
CATH (12)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4r8zA00 1.10.3210.10 Mainly Alpha › Orthogonal Bundle › Hypothetical protein af1432 › Hypothetical protein af1432 0.67 57.0 4.24e-01 95.2% 91.7%
3t69A02 3.30.420.310 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › 2-keto-3-deoxy-galactonokinase, C-terminal domain 0.65 34.0 2.50e-01 86.7% 18.6%
2ot4A03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.63 43.0 3.98e-01 71.1% 86.9%
3h4cA01 1.10.472.10 Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like 0.61 45.0 4.28e-01 77.1% 83.3%
1gnlA01 1.20.1270.20 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.61 52.0 4.42e-01 95.2% 73.4%
4px7A00 1.20.144.10 Mainly Alpha › Up-down Bundle › Vanadium-containing Chloroperoxidase; domain 1 › Phosphatidic acid phosphatase type 2/haloperoxidase 0.58 42.0 3.02e-01 75.9% 55.0%
2b9rA01 1.10.472.10 Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like 0.57 46.0 4.00e-01 92.8% 70.0%
3fhdA01 1.20.120.860 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Herpesvirus alkaline exonuclease, N-terminal domain 0.56 41.0 3.56e-01 78.3% 63.2%
4gr6B00 1.10.1200.210 Mainly Alpha › Orthogonal Bundle › Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A › Chaperonin-like RbcX 0.54 43.0 4.09e-01 91.6% 74.3%
2eduA01 1.10.150.280 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › AF1531-like domain 0.53 40.0 4.09e-01 81.9% 91.4%
3lcnB00 1.10.340.40 Mainly Alpha › Orthogonal Bundle › Endonuclease III; domain 1 › Nuclear abundant poly(A) RNA-bind protein 2, N-terminal domain 0.53 43.0 4.16e-01 91.6% 80.4%
1khyD00 1.10.1780.10 Mainly Alpha › Orthogonal Bundle › Double Clp-N motif › Clp, N-terminal domain 0.50 36.0 3.10e-01 75.9% 97.8%
ECOD (13)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3672657 3755.4.1.23 ↗ alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › DUF7032 0.65 45.0 3.67e-01 71.1% 58.7%
3241631 101.1.10.7 ↗ alpha arrays › HTH › HTH › Cyclin-like › Cyclin_C 0.62 52.0 4.31e-01 95.2% 69.7%
3517691 101.1.10.7 ↗ alpha arrays › HTH › HTH › Cyclin-like › Cyclin_C 0.61 50.0 4.51e-01 92.8% 81.7%
3991361 101.1.10.7 ↗ alpha arrays › HTH › HTH › Cyclin-like › Cyclin_C 0.60 49.0 4.29e-01 91.6% 74.6%
3719289 101.1.10.7 ↗ alpha arrays › HTH › HTH › Cyclin-like › Cyclin_C 0.60 49.0 4.24e-01 91.6% 82.2%
3736558 101.1.10.7 ↗ alpha arrays › HTH › HTH › Cyclin-like › Cyclin_C 0.59 49.0 4.43e-01 92.8% 76.5%
4542785 101.1.10.7 ↗ alpha arrays › HTH › HTH › Cyclin-like › Cyclin_C 0.59 48.0 4.29e-01 90.4% 80.0%
3310282 101.1.10.7 ↗ alpha arrays › HTH › HTH › Cyclin-like › Cyclin_C 0.59 48.0 4.28e-01 90.4% 80.0%
3272263 101.1.10.7 ↗ alpha arrays › HTH › HTH › Cyclin-like › Cyclin_C 0.58 47.0 4.22e-01 90.4% 80.8%
3494861 101.1.10.0 ↗ alpha arrays › HTH › HTH › Cyclin-like 0.56 41.0 4.00e-01 78.3% 82.1%
3412630 101.1.10.7 ↗ alpha arrays › HTH › HTH › Cyclin-like › Cyclin_C 0.55 44.0 3.82e-01 90.4% 85.9%
3836118 101.1.10.7 ↗ alpha arrays › HTH › HTH › Cyclin-like › Cyclin_C 0.54 44.0 4.07e-01 91.6% 84.5%
3243583 198.1.1.1 ↗ alpha arrays › Saposin-like › Saposin-like › Saposin-like › SapB_2 0.54 33.0 3.36e-01 89.2% 60.0%
D4 medium residues 1-35_123-195_361-384
PDB
Domain cluster: rep: heat-shock_protein__NP_619695__Lettuce_infectious_yellows_virus__31713__D2-172
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF00012.27 best HSP70 34.1 1.30e-08 54.5% 10.3%
D5 medium residues 36-122
PDB
Domain cluster: representative
CATH (9)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1qypA00 2.20.25.10 Mainly Beta › Single Sheet › N-terminal domain of TfIIb › 0.64 31.0 3.74e-01 100.0% 68.4%
3po3S02 2.20.25.10 Mainly Beta › Single Sheet › N-terminal domain of TfIIb › 0.61 29.0 3.17e-01 100.0% 51.4%
2n8lA00 3.30.310.210 Alpha Beta › 2-Layer Sandwich › TATA-Binding Protein › 0.57 46.0 3.67e-01 90.8% 71.7%
1x49A01 3.30.160.20 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › 0.55 30.0 3.26e-01 100.0% 62.9%
3l4gC04 3.30.930.10 Alpha Beta › 2-Layer Sandwich › BirA Bifunctional Protein; domain 2 › Bira Bifunctional Protein; Domain 2 0.54 44.0 3.20e-01 92.0% 79.9%
6gmhI02 2.20.25.10 Mainly Beta › Single Sheet › N-terminal domain of TfIIb › 0.53 34.0 3.67e-01 77.0% 81.2%
3nybA02 3.30.460.10 Alpha Beta › 2-Layer Sandwich › Beta Polymerase; domain 2 › Beta Polymerase, domain 2 0.51 41.0 3.87e-01 89.7% 92.7%
3qwuA03 3.30.70.2160 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.51 41.0 3.64e-01 93.1% 85.6%
5w2fA01 3.30.780.10 Alpha Beta › 2-Layer Sandwich › Translation Initiation Factor Eif1 › SUI1-like domain 0.50 33.0 3.39e-01 89.7% 68.6%
ECOD (19)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3705742 375.1.1.7 ↗ few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related › TFIIS_C 0.65 31.0 3.71e-01 100.0% 67.2%
5048721 375.1.1.7 ↗ few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related › TFIIS_C 0.64 31.0 3.52e-01 100.0% 60.0%
3816604 375.1.1.7 ↗ few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related › TFIIS_C 0.63 30.0 3.42e-01 100.0% 58.5%
5038934 375.1.1.7 ↗ few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related › TFIIS_C 0.63 30.0 3.61e-01 100.0% 67.2%
3804890 375.1.1.7 ↗ few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related › TFIIS_C 0.62 29.0 3.49e-01 100.0% 64.4%
4963635 375.1.1.7 ↗ few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related › TFIIS_C 0.60 30.0 3.30e-01 100.0% 56.5%
3598298 375.1.1.0 ↗ few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related 0.60 32.0 3.67e-01 100.0% 71.7%
4938000 242.1.1.7 ↗ a+b two layers › Homing endonucleases-like › Homing endonucleases › Homing endonucleases › LAGLIDADG_3 0.58 37.0 3.69e-01 92.0% 58.9%
3263635 375.1.1.0 ↗ few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related 0.58 30.0 3.33e-01 100.0% 61.5%
4013714 375.1.1.0 ↗ few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related 0.57 30.0 3.72e-01 100.0% 89.6%
4101190 330.1.1.1 ↗ a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like › dsrm 0.57 32.0 3.38e-01 100.0% 60.0%
3951204 321.1.1.11 ↗ a+b two layers › Glutamine synthetase-like › Glutamine synthetase/guanido kinase › Glutamine synthetase/guanido kinase › DUF2126 0.55 44.0 3.06e-01 92.0% 65.4%
3487047 375.1.1.0 ↗ few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related 0.55 31.0 3.60e-01 97.7% 80.0%
3445009 103.4.1.0 ↗ alpha arrays › RuvA-C › Elongation factor TFIIS domain 2/ Kix domain of creb binding protein › Elongation factor TFIIS domain 2/ Kix domain of creb binding protein 0.54 29.0 2.31e-01 100.0% 22.9%
3655146 221.1.2.0 ↗ a+b two layers › beta-Grasp › Ubiquitin-related › Alpha-L RNA-binding motif 0.54 40.0 3.94e-01 100.0% 74.7%
1179397 316.1.1.36 ↗ a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase › MTPAP-like_central 0.52 42.0 3.55e-01 92.0% 67.3%
None — 0.51 35.0 3.52e-01 89.7% 68.9%
3585868 327.11.2.1 ↗ a+b two layers › Alpha-lytic protease prodomain-like › KH-domains › Eukaryotic type KH-domain (KH-domain type I) › KH_1 0.50 35.0 3.54e-01 82.8% 74.1%
4360324 3398.1.1.2 ↗ a/b three-layered sandwiches › STING C-terminal domain › STING C-terminal domain › STING C-terminal domain › prok_STING 0.50 34.0 2.86e-01 89.7% 38.7%