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ICP22

Euk-Vir

Macropodid_alphaherpesvirus_1

ICP22__YP_009227219__Macropodid_alphaherpesvirus_1__137443

Identity

Accession:
YP_009227219 ↗
Protein ID:
ICP22
Kingdom:
euk

Quality

46.8 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 263-344
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF02479.22 best Herpes_IE68 61.7 8.10e-17 96.3% 53.0%
CATH (14)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4wzxA01 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.64 33.0 3.52e-01 92.7% 56.0%
2guzA00 1.10.287.110 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › DnaJ domain 0.63 34.0 3.67e-01 91.5% 60.6%
1yxrA01 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.60 33.0 3.51e-01 92.7% 60.8%
2fji102 1.10.357.70 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Exocyst complex component Sec6, C-terminal domain 0.55 41.0 3.25e-01 82.9% 64.7%
3r84A00 1.10.287.3490 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.55 32.0 3.29e-01 92.7% 59.3%
4pcqA01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.54 31.0 3.80e-01 95.1% 94.0%
3da1A03 1.10.8.870 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Alpha-glycerophosphate oxidase, cap domain 0.54 43.0 3.73e-01 90.2% 68.4%
3l8rA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.51 36.0 3.38e-01 74.4% 99.0%
2a3vB01 1.10.150.130 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Tyrosine recombinase, N-terminal domain 0.51 36.0 3.48e-01 74.4% 93.6%
5je8B02 1.10.1040.10 Mainly Alpha › Orthogonal Bundle › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 0.51 42.0 3.73e-01 95.1% 69.5%
3ghyA02 1.10.1040.10 Mainly Alpha › Orthogonal Bundle › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 0.51 42.0 3.69e-01 92.7% 81.6%
3wxmB03 3.30.1330.30 Alpha Beta › 2-Layer Sandwich › 60s Ribosomal Protein L30; Chain: A; › Ribosomal protein L30/S12 0.51 33.0 3.05e-01 76.8% 51.4%
2lvsA01 1.10.10.60 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like 0.50 33.0 3.82e-01 93.9% 100.0%
2vsoF01 1.25.40.180 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.50 44.0 3.24e-01 98.8% 58.9%
ECOD (6)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3619662 192.12.1.3 alpha bundles › Long alpha-hairpin › Transcriptional repressor TraM › Transcriptional repressor TraM › DUF747 0.62 33.0 3.40e-01 90.2% 52.5%
3801688 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.61 37.0 3.41e-01 92.7% 48.6%
3560818 109.4.1.1497 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › HEAT, CLASP_N, XMAP215_CLASP_TOG 0.53 38.0 2.41e-01 79.3% 26.6%
3743077 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.52 37.0 3.29e-01 75.6% 77.6%
3502677 101.1.2.22 alpha arrays › HTH › HTH › winged helix domain › PCI 0.52 43.0 3.65e-01 96.3% 60.0%
3792971 102.1.1.0 alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › SAM domain-like 0.51 34.0 3.63e-01 93.9% 79.5%