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IMGVR_UViG_2264265223_000004-2264265223-2264774713

Arc-Vir

IMGVR_UViG_2264265223_000004-2264265223-2264774713

Identity

Kingdom:
archaea

Quality

94.7 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 2-22_146-180
PDB
CATH (68)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
5exvC00 3.40.1570.10 Alpha Beta › 3-Layer(aba) Sandwich › Heme iron utilization protein-like fold › HemS/ChuS/ChuX like domains 0.77 60.0 4.24e-01 83.9% 72.7%
6eotD01 2.140.10.30 Mainly Beta › 8 Propeller › Methanol Dehydrogenase; Chain A › Dipeptidylpeptidase IV, N-terminal domain 0.77 66.0 3.80e-01 96.4% 27.5%
2xwxA03 2.60.40.2550 Mainly Beta › Sandwich › Immunoglobulin-like › 0.73 50.0 4.12e-01 71.4% 71.4%
3ll3B01 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.73 57.0 3.69e-01 85.7% 24.9%
4dm5A00 3.30.1450.10 Alpha Beta › 2-Layer Sandwich › Beta-lactamase Inhibitory Protein; Chain:B, domain 1 › 0.73 59.0 5.08e-01 100.0% 57.5%
2ap1A01 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.72 57.0 4.24e-01 85.7% 37.4%
5tz6B02 3.10.129.120 Alpha Beta › Roll › Thiol Ester Dehydrase; Chain A › 0.72 55.0 3.99e-01 82.1% 67.5%
3dsmA00 2.130.10.10 Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › YVTN repeat-like/Quinoprotein amine dehydrogenase 0.71 64.0 3.92e-01 100.0% 20.5%
3a9gA00 2.120.10.30 Mainly Beta › 6 Propeller › Neuraminidase › TolB, C-terminal domain 0.71 63.0 3.85e-01 100.0% 27.2%
1z05A02 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.70 55.0 3.99e-01 85.7% 34.4%
1plqA00 3.70.10.10 Alpha Beta › Box › Proliferating Cell Nuclear Antigen › 0.70 51.0 3.32e-01 78.6% 45.7%
2f9wA01 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.70 48.0 3.68e-01 83.9% 30.5%
1sxjH01 3.10.150.10 Alpha Beta › Roll › DNA Polymerase III; Chain A, domain 2 › DNA Polymerase III, subunit A, domain 2 0.70 50.0 3.88e-01 76.8% 94.4%
3vsfC01 2.115.10.20 Mainly Beta › 5 Propeller › Tachylectin-2; Chain A › Glycosyl hydrolase domain; family 43 0.69 60.0 3.72e-01 100.0% 29.5%
4eo3A01 3.40.30.10 Alpha Beta › 3-Layer(aba) Sandwich › Glutaredoxin › Glutaredoxin 0.69 54.0 4.01e-01 83.9% 76.8%
3htvA01 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.69 54.0 4.33e-01 85.7% 44.1%
5c86A02 2.60.40.10 Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins 0.69 47.0 3.88e-01 71.4% 79.2%
2k5qA00 2.40.50.480 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Protein of unknown function DUF1093 0.68 48.0 3.94e-01 75.0% 80.0%
6eugA00 2.115.10.20 Mainly Beta › 5 Propeller › Tachylectin-2; Chain A › Glycosyl hydrolase domain; family 43 0.68 59.0 3.65e-01 100.0% 24.5%
3h6eB01 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.68 54.0 4.48e-01 87.5% 61.6%
2gupA01 3.30.420.40 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain 0.68 51.0 4.28e-01 82.1% 47.4%
6eufA01 2.115.10.20 Mainly Beta › 5 Propeller › Tachylectin-2; Chain A › Glycosyl hydrolase domain; family 43 0.68 59.0 3.71e-01 100.0% 27.9%
3psfA04 3.30.420.140 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › YqgF/RNase H-like domain 0.68 51.0 3.73e-01 83.9% 33.5%
2w18A00 2.130.10.10 Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › YVTN repeat-like/Quinoprotein amine dehydrogenase 0.67 58.0 3.67e-01 100.0% 24.5%
6j9eJ00 3.30.160.560 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › 0.67 59.0 5.59e-01 100.0% 83.3%
5umsA02 2.30.29.30 Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 0.67 52.0 4.28e-01 85.7% 58.8%
2oqbA00 2.30.29.30 Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 0.66 60.0 4.78e-01 100.0% 75.9%
1u9tA02 3.40.1570.10 Alpha Beta › 3-Layer(aba) Sandwich › Heme iron utilization protein-like fold › HemS/ChuS/ChuX like domains 0.66 57.0 4.07e-01 96.4% 58.0%
3cm1A00 2.30.31.20 Mainly Beta › Roll › Transcriptional Co-activator pc4; Chain A › Sporulation-specific cell division protein SsgB 0.66 56.0 4.33e-01 100.0% 67.6%
3kxyJ00 3.30.1460.10 Alpha Beta › 2-Layer Sandwich › Yope Regulator; Chain: A, › 0.66 57.0 4.45e-01 100.0% 67.4%
2fgzA01 2.60.40.1130 Mainly Beta › Sandwich › Immunoglobulin-like › Rab geranylgeranyltransferase alpha-subunit, insert domain 0.66 48.0 3.78e-01 76.8% 82.6%
3k44B00 3.30.2450.30 Alpha Beta › 2-Layer Sandwich › Secreted effector protein pipB2 fold › 0.64 55.0 4.13e-01 96.4% 40.0%
3fyfA00 2.40.128.410 Mainly Beta › Beta Barrel › Lipocalin › 0.64 50.0 3.77e-01 89.3% 34.2%
2yh9B00 3.30.1450.10 Alpha Beta › 2-Layer Sandwich › Beta-lactamase Inhibitory Protein; Chain:B, domain 1 › 0.63 43.0 4.05e-01 71.4% 66.2%
4u6bA00 2.115.10.20 Mainly Beta › 5 Propeller › Tachylectin-2; Chain A › Glycosyl hydrolase domain; family 43 0.63 53.0 3.34e-01 98.2% 27.4%
2c4iA01 2.40.128.30 Mainly Beta › Beta Barrel › Lipocalin › Avidin-like 0.63 54.0 4.33e-01 100.0% 81.4%
3pvlA04 2.30.29.30 Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 0.63 56.0 4.64e-01 100.0% 73.7%
6j8yC00 3.70.10.10 Alpha Beta › Box › Proliferating Cell Nuclear Antigen › 0.62 47.0 3.06e-01 78.6% 47.5%
2oa9B02 3.30.70.3570 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › MvaI/BcnI restriction endonuclease, recognition domain 0.62 52.0 4.07e-01 96.4% 61.4%
7lt2A01 3.30.460.90 Alpha Beta › 2-Layer Sandwich › Beta Polymerase; domain 2 › 0.62 44.0 2.94e-01 76.8% 20.8%
3imoC00 3.30.920.70 Alpha Beta › 2-Layer Sandwich › Metal Transport, Frataxin; Chain A › 0.62 51.0 4.14e-01 100.0% 47.7%
1z5yE00 3.40.30.10 Alpha Beta › 3-Layer(aba) Sandwich › Glutaredoxin › Glutaredoxin 0.62 48.0 3.59e-01 83.9% 76.5%
8c5iA01 3.60.110.10 Alpha Beta › 4-Layer Sandwich › Nitrilase/N-carbamoyl-D-aminoacid amidohydrolase › Carbon-nitrogen hydrolase 0.61 51.0 3.24e-01 96.4% 57.7%
3u12A00 2.30.29.180 Mainly Beta › Roll › PH-domain like › Ubiquitin carboxyl-terminal hydrolase 26/29/37, pleckstrin homology-like domain 0.60 46.0 3.83e-01 89.3% 45.2%
2db2A01 3.30.160.20 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › 0.60 49.0 4.19e-01 92.9% 64.9%
3gkmA00 3.40.30.10 Alpha Beta › 3-Layer(aba) Sandwich › Glutaredoxin › Glutaredoxin 0.60 54.0 3.85e-01 100.0% 85.4%
1h7sA01 3.30.565.10 Alpha Beta › 2-Layer Sandwich › Heat Shock Protein 90 › Histidine kinase-like ATPase, C-terminal domain 0.59 45.0 3.08e-01 80.4% 36.8%
1bqnA05 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.59 45.0 3.51e-01 87.5% 36.6%
1a1xA00 2.40.15.10 Mainly Beta › Beta Barrel › Proto-oncogene - Oncogene Product P14tcl1 › TCL1/MTCP1 0.59 45.0 3.72e-01 85.7% 84.0%
4ob9A00 3.60.150.10 Alpha Beta › 4-Layer Sandwich › Chorismate synthase, AroC fold › Chorismate synthase AroC 0.58 50.0 3.15e-01 98.2% 33.9%
3eliA00 3.30.530.20 Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › START domain 0.58 49.0 3.75e-01 100.0% 54.9%
4v19S00 3.30.420.80 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribosomal protein S11/S14 0.58 48.0 3.68e-01 96.4% 68.5%
2hjjA00 3.30.160.130 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › ykff protein like domains 0.58 45.0 4.31e-01 100.0% 75.8%
2kvtA00 3.30.730.30 Alpha Beta › 2-Layer Sandwich › GCC-box Binding Domain › YaiA protein 0.57 43.0 4.05e-01 85.7% 67.6%
1ei5A01 3.40.710.10 Alpha Beta › 3-Layer(aba) Sandwich › Beta-lactamase › DD-peptidase/beta-lactamase superfamily 0.56 48.0 3.03e-01 100.0% 81.6%
2kgtA00 2.30.30.40 Mainly Beta › Roll › SH3 type barrels. › SH3 Domains 0.55 45.0 4.24e-01 94.6% 81.9%
4e6xB00 3.40.710.10 Alpha Beta › 3-Layer(aba) Sandwich › Beta-lactamase › DD-peptidase/beta-lactamase superfamily 0.54 46.0 2.97e-01 100.0% 78.1%
4tyzA00 2.30.29.30 Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 0.54 44.0 3.71e-01 100.0% 64.2%
3rf9B02 3.20.20.70 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I 0.53 46.0 2.98e-01 100.0% 94.1%
4ntqA00 3.10.380.20 Alpha Beta › Roll › Ribonuclease domain of colicin e3 (Residues 456-551) › Novel toxin 21 (CdiA), C-terminal domain 0.53 45.0 4.16e-01 100.0% 93.4%
1mpgA01 3.30.310.20 Alpha Beta › 2-Layer Sandwich › TATA-Binding Protein › DNA-3-methyladenine glycosylase AlkA, N-terminal domain 0.53 45.0 3.61e-01 96.4% 70.5%
4mtsA00 3.10.180.10 Alpha Beta › Roll › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase; domain 1 › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1 0.52 42.0 3.36e-01 94.6% 82.2%
2qpvA00 3.30.530.20 Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › START domain 0.52 43.0 3.34e-01 94.6% 59.8%
3icyA00 3.30.450.20 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › PAS domain 0.52 37.0 3.03e-01 78.6% 48.3%
3cjxA01 2.60.120.10 Mainly Beta › Sandwich › Jelly Rolls › Jelly Rolls 0.51 38.0 2.81e-01 80.4% 57.3%
3a0oA03 2.70.98.70 Mainly Beta › Distorted Sandwich › Beta-galactosidase; Chain A, domain 5 › 0.51 44.0 2.84e-01 100.0% 83.3%
3a1jB00 3.70.10.10 Alpha Beta › Box › Proliferating Cell Nuclear Antigen › 0.50 37.0 2.51e-01 85.7% 37.2%
6u8yL01 1.10.645.10 Mainly Alpha › Orthogonal Bundle › Cytochrome-c3 Hydrogenase; chain B › Cytochrome-c3 Hydrogenase, chain B 0.50 41.0 2.58e-01 98.2% 99.2%
ECOD (89)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
5003245 243.8.1.0 a+b two layers › Cystatin-like › Uracil-DNA glycosylase inhibitor protein › Uracil-DNA glycosylase inhibitor protein 0.83 57.0 5.24e-01 75.0% 57.1%
4952072 4325.1.1.0 mixed a+b and a/b › YegP-like › YegP-like › YegP-like 0.83 61.0 6.43e-01 85.7% 88.0%
5038443 243.3.1.0 a+b two layers › Cystatin-like › Cystatin/monellin › Cystatin/monellin 0.80 61.0 5.45e-01 80.4% 60.0%
3602236 284.1.3.3 a+b two layers › FKBP-like › FKBP-like › WNK1 autoinhibitory domain › DUF4346 0.79 58.0 4.87e-01 91.1% 46.3%
3977419 3844.1.1.1 a+b two layers › hydrogenase expression protein-like › hydrogenase expression protein-like › hydrogenase expression protein › HupH_C 0.79 64.0 5.25e-01 96.4% 49.0%
4965680 2484.1.1.330 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DUF460 0.78 56.0 4.02e-01 87.5% 27.7%
3995669 5.1.3.0 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed 0.78 69.0 4.44e-01 98.2% 30.2%
4959306 5.1.3.0 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed 0.76 68.0 4.12e-01 98.2% 21.8%
5052931 5.1.4.0 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed 0.76 68.0 4.04e-01 100.0% 21.3%
3587844 2484.1.1.0 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.76 57.0 4.54e-01 85.7% 40.0%
3481354 5.1.4.0 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed 0.76 68.0 4.15e-01 100.0% 22.4%
3241605 5.1.3.0 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed 0.76 62.0 3.83e-01 89.3% 28.7%
4004717 3844.1.1.1 a+b two layers › hydrogenase expression protein-like › hydrogenase expression protein-like › hydrogenase expression protein › HupH_C 0.75 58.0 4.65e-01 96.4% 42.7%
4364087 3844.1.1.1 a+b two layers › hydrogenase expression protein-like › hydrogenase expression protein-like › hydrogenase expression protein › HupH_C 0.75 63.0 4.90e-01 100.0% 44.3%
4949536 5.1.4.0 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed 0.75 66.0 4.02e-01 100.0% 24.1%
3744781 109.4.1.69 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › IKI3 0.74 66.0 4.14e-01 100.0% 50.0%
5034332 5.1.4.0 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed 0.74 66.0 4.28e-01 100.0% 31.0%
5037531 5.1.3.0 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed 0.73 65.0 3.65e-01 100.0% 12.1%
4278695 2484.1.1.101 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DDE_Tnp_IS240 0.73 56.0 5.00e-01 85.7% 58.7%
1031811 222.1.1.12 a+b two layers › Thioesterase/thiol ester dehydrase-isomerase-like › Thioesterase/thiol ester dehydrase-isomerase › Thioesterase/thiol ester dehydrase-isomerase › PS-DH 0.73 59.0 4.12e-01 87.5% 63.0%
2442100 227.1.1.1 a+b two layers › DNA clamp › DNA clamp › DNA clamp › PCNA_N 0.72 53.0 3.98e-01 78.6% 88.2%
3242741 207.1.1.81 beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Leucine-rich repeats › Leucine-rich repeats › FTH 0.72 60.0 3.82e-01 98.2% 19.0%
3240119 243.1.1.75 a+b two layers › Cystatin-like › NTF2-like › NTF2-like › PF26530 0.72 48.0 3.88e-01 75.0% 37.1%
5057579 5.1.4.43 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › FG-GAP_3 0.72 64.0 3.86e-01 100.0% 32.5%
4102064 3844.1.1.1 a+b two layers › hydrogenase expression protein-like › hydrogenase expression protein-like › hydrogenase expression protein › HupH_C 0.72 57.0 4.66e-01 96.4% 46.7%
1249950 809.2.1.0 a+b two layers › BLIP-like › BT0923-like › BT0923-like 0.71 64.0 5.56e-01 100.0% 67.9%
3605927 708.1.1.0 beta complex topology › ETN0001 domain-like › ETN0001 domain-like › NAC/WRKY/GCM/WOPR domain 0.71 53.0 4.14e-01 80.4% 51.7%
4088247 5.1.5.4 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 8-bladed › DPPIV_N 0.71 63.0 3.71e-01 100.0% 17.8%
5055952 5.1.5.0 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 8-bladed 0.71 63.0 3.88e-01 100.0% 22.1%
3277064 5.1.4.0 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed 0.71 62.0 4.33e-01 96.4% 35.3%
3968013 5.1.4.0 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed 0.71 62.0 4.01e-01 100.0% 28.1%
5013654 5.1.5.11 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 8-bladed › PQQ_2 0.71 63.0 3.88e-01 100.0% 21.5%
3929846 5.1.3.0 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed 0.71 62.0 3.89e-01 100.0% 35.1%
4591449 7556.1.1.1 a/b three-layered sandwiches › Fe-only hydrogenase › Fe-only hydrogenase › Fe-only hydrogenase › Fe_hyd_lg_C 0.70 50.0 2.93e-01 73.2% 18.9%
3653889 5.1.3.0 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed 0.70 61.0 3.77e-01 100.0% 27.6%
3520418 227.1.1.1 a+b two layers › DNA clamp › DNA clamp › DNA clamp › PCNA_N 0.70 51.0 3.77e-01 78.6% 91.3%
3975425 3844.1.1.1 a+b two layers › hydrogenase expression protein-like › hydrogenase expression protein-like › hydrogenase expression protein › HupH_C 0.70 60.0 4.88e-01 98.2% 51.4%
3238362 5.1.4.0 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed 0.70 61.0 3.84e-01 100.0% 26.5%
3700528 220.1.1.0 beta barrels › PH domain-like › PH domain-like › PH domain-like 0.69 61.0 4.72e-01 100.0% 67.2%
3221976 5.1.4.1 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › WD40 0.69 62.0 3.70e-01 100.0% 27.5%
4030625 219.1.1.97 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › CEPT76_peptidase 0.69 59.0 3.92e-01 96.4% 46.1%
5054384 331.10.2.0 a+b two layers › TBP-like › S-adenosylmethionine decarboxylase-related › Bacterial S-adenosylmethionine decarboxylase 0.69 48.0 4.50e-01 75.0% 58.6%
3755983 708.1.1.0 beta complex topology › ETN0001 domain-like › ETN0001 domain-like › NAC/WRKY/GCM/WOPR domain 0.69 53.0 4.48e-01 83.9% 55.8%
3515139 220.1.1.0 beta barrels › PH domain-like › PH domain-like › PH domain-like 0.69 50.0 3.51e-01 76.8% 39.7%
3627778 220.1.1.64 beta barrels › PH domain-like › PH domain-like › PH domain-like › FERM_C1_MyoVII 0.68 56.0 4.61e-01 89.3% 91.0%
4413086 2484.1.1.37 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Pan_kinase 0.68 52.0 3.95e-01 83.9% 60.7%
5079230 216.1.1.0 a+b two layers › UBC-like › UBC-like › UBC-like 0.68 58.0 4.83e-01 100.0% 61.0%
5021156 5.1.3.0 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed 0.68 59.0 4.08e-01 100.0% 39.0%
3936442 220.1.1.0 beta barrels › PH domain-like › PH domain-like › PH domain-like 0.67 55.0 4.70e-01 96.4% 74.0%
360186 809.1.1.2 a+b two layers › BLIP-like › beta-lactamase-inhibitor protein, BLIP › beta-lactamase-inhibitor protein, BLIP › BLIP 0.67 46.0 4.21e-01 76.8% 54.8%
4965041 247.1.1.1 a+b four layers › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Lactamase_B 0.66 52.0 3.31e-01 85.7% 74.2%
4643569 2484.1.1.37 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Pan_kinase 0.66 51.0 3.85e-01 83.9% 60.0%
4938162 11.1.1.0 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.66 57.0 4.92e-01 98.2% 83.3%
4606701 7556.1.1.1 a/b three-layered sandwiches › Fe-only hydrogenase › Fe-only hydrogenase › Fe-only hydrogenase › Fe_hyd_lg_C 0.66 46.0 2.83e-01 71.4% 20.3%
4012865 222.1.1.0 a+b two layers › Thioesterase/thiol ester dehydrase-isomerase-like › Thioesterase/thiol ester dehydrase-isomerase › Thioesterase/thiol ester dehydrase-isomerase 0.66 54.0 3.91e-01 91.1% 88.4%
4216191 3844.1.1.1 a+b two layers › hydrogenase expression protein-like › hydrogenase expression protein-like › hydrogenase expression protein › HupH_C 0.65 51.0 4.18e-01 100.0% 45.7%
3737835 241.15.1.0 a+b two layers › Type III secretory system chaperone-like › FP (Fbxo7/PI31) dimerization domain › FP (Fbxo7/PI31) dimerization domain 0.65 56.0 4.68e-01 100.0% 55.0%
4023222 7556.1.1.0 a/b three-layered sandwiches › Fe-only hydrogenase › Fe-only hydrogenase › Fe-only hydrogenase 0.65 48.0 2.92e-01 78.6% 18.0%
4660064 2484.1.1.37 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Pan_kinase 0.64 49.0 3.76e-01 83.9% 59.2%
4248250 4041.1.1.1 a+b complex topology › insertion domain in beta subunit of DNA dependent RNA-polymerase › insertion domain in beta subunit of DNA dependent RNA-polymerase › insertion domain in beta subunit of DNA dependent RNA-polymerase › RNA_pol_Rpb2_2 0.64 45.0 3.10e-01 75.0% 22.2%
3614410 227.1.1.0 a+b two layers › DNA clamp › DNA clamp › DNA clamp 0.64 47.0 3.46e-01 80.4% 85.1%
4975431 331.3.1.0 a+b two layers › TBP-like › Bet v1-like › Bet v1-like 0.63 53.0 4.53e-01 92.9% 80.0%
3265334 216.1.1.0 a+b two layers › UBC-like › UBC-like › UBC-like 0.63 45.0 3.66e-01 76.8% 47.3%
4508538 7556.1.1.1 a/b three-layered sandwiches › Fe-only hydrogenase › Fe-only hydrogenase › Fe-only hydrogenase › Fe_hyd_lg_C 0.63 51.0 3.03e-01 87.5% 27.2%
5082332 244.4.1.2 a+b two layers › FAD-linked reductases, C-terminal domain-like › Ni-Fe binding domain in nickel-iron hydrogenase large subunit › Ni-Fe binding domain in nickel-iron hydrogenase large subunit › NiFeSe_Hases 0.63 45.0 3.71e-01 76.8% 57.0%
3281300 4.1.1.426 beta barrels › SH3 › SH3 › SH3 › PF31188 0.62 46.0 4.43e-01 85.7% 70.8%
3670605 330.1.1.3 a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like › Dicer_dimer 0.62 51.0 4.38e-01 92.9% 72.2%
4959054 11.1.1.0 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.61 52.0 4.59e-01 98.2% 96.5%
3799509 225.1.1.7 a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c_3 0.60 45.0 3.06e-01 80.4% 37.6%
3841889 225.1.1.7 a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c_3 0.60 45.0 3.02e-01 80.4% 37.6%
3472236 225.1.1.7 a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › HATPase_c_3 0.59 45.0 2.99e-01 80.4% 35.6%
3255344 220.1.1.27 beta barrels › PH domain-like › PH domain-like › PH domain-like › PH_RBD 0.59 49.0 3.99e-01 100.0% 72.5%
3604410 2004.1.1.293 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_15 0.58 50.0 3.55e-01 100.0% 33.3%
4945471 375.1.1.0 few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related 0.58 48.0 4.69e-01 100.0% 89.2%
4312097 295.1.1.15 a+b two layers › ssDNA-binding transcriptional regulator domain-like › ssDNA-binding transcriptional regulator domain › ssDNA-binding transcriptional regulator domain › UPF0128 0.58 46.0 3.41e-01 96.4% 84.6%
3563547 220.1.1.27 beta barrels › PH domain-like › PH domain-like › PH domain-like › PH_RBD 0.57 46.0 3.76e-01 100.0% 72.0%
4856205 1032.1.1.2 alpha arrays › Toxin A (TcdA) helical domain › Toxin A (TcdA) helical domain › Toxin A (TcdA) helical domain › TcdA_TcdB_pore, PF30720 0.56 39.0 2.68e-01 75.0% 34.9%
3208809 9.2.1.2 beta barrels › Lipocalins/Streptavidin › Avidin/Streptavidin › Avidin/Streptavidin › Vac_ImportDeg 0.55 44.0 3.08e-01 98.2% 57.1%
6297 331.1.1.3 a+b two layers › TBP-like › TATA-box binding protein-like › TATA-box binding protein-like › AlkA_N 0.54 44.0 3.70e-01 91.1% 53.5%
3596085 12.1.1.0 beta sandwiches › Glycosyl hydrolase domain-like › Glycosyl hydrolase domain › Glycosyl hydrolase domain 0.54 45.0 4.10e-01 98.2% 75.0%
3810543 220.1.1.20 beta barrels › PH domain-like › PH domain-like › PH domain-like › PH_TFIIH 0.54 45.0 3.72e-01 100.0% 67.3%
3651210 386.1.1.0 few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers 0.53 39.0 3.85e-01 96.4% 76.7%
3946798 244.2.1.7 a+b two layers › FAD-linked reductases, C-terminal domain-like › FAD/NAD-linked reduatases, dimerisation (C-terminal) domain › FAD/NAD-linked reduatases, dimerisation (C-terminal) domain › Rubredoxin_C 0.53 44.0 3.66e-01 98.2% 70.5%
3972580 331.1.1.3 a+b two layers › TBP-like › TATA-box binding protein-like › TATA-box binding protein-like › AlkA_N 0.53 42.0 3.75e-01 96.4% 62.5%
3232165 4.1.1.54 beta barrels › SH3 › SH3 › SH3 › SH3_2 0.53 42.0 3.74e-01 94.6% 96.7%
3600818 2485.1.1.0 a+b three layers › Thioredoxin-like › Thioredoxin-like › Thioredoxin-like 0.52 46.0 3.17e-01 100.0% 90.4%
2491359 243.19.1.0 a+b two layers › Cystatin-like › Phi ETA orf 56-like protein C-terminal domains › Phi ETA orf 56-like protein C-terminal domains 0.52 42.0 3.34e-01 98.2% 50.0%
3710561 4.1.1.92 beta barrels › SH3 › SH3 › SH3 › SH3_9 0.50 43.0 4.17e-01 100.0% 92.3%
3585016 4.1.1.1 beta barrels › SH3 › SH3 › SH3 › SH3_1 0.50 39.0 3.83e-01 87.5% 83.3%
D2 high residues 34-144
PDB