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IMGVR_UViG_2502082094_000002-2502082094-2502095596
Arc-VirIMGVR_UViG_2502082094_000002-2502082094-2502095596
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
medium
residues 1-105_130-196
Domain cluster:
rep: ribonucleotide_reductase_subunit_2__YP_009052007__Elephant_endotheliotropic_herpesvirus_5__768738__D11-211
Pfam (2)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF00268.28 best | Ribonuc_red_sm | 59.8 | 4.00e-16 | 63.4% | 36.6% |
| PF00268.28 | Ribonuc_red_sm | 36.7 | 4.40e-09 | 43.0% | 23.1% |
CATH (38)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5olkB01 | 1.10.620.20 | Mainly Alpha › Orthogonal Bundle › Ribonucleotide Reductase, subunit A › Ribonucleotide Reductase, subunit A | 0.99 | 98.0 | 7.96e-01 | 100.0% | 70.3% |
| 2aniA00 | 1.10.620.20 | Mainly Alpha › Orthogonal Bundle › Ribonucleotide Reductase, subunit A › Ribonucleotide Reductase, subunit A | 0.93 | 91.0 | 7.11e-01 | 100.0% | 65.3% |
| 1biqA00 | 1.10.620.20 | Mainly Alpha › Orthogonal Bundle › Ribonucleotide Reductase, subunit A › Ribonucleotide Reductase, subunit A | 0.91 | 88.0 | 6.79e-01 | 100.0% | 66.5% |
| 3ee4A00 | 1.10.620.20 | Mainly Alpha › Orthogonal Bundle › Ribonucleotide Reductase, subunit A › Ribonucleotide Reductase, subunit A | 0.91 | 87.0 | 7.11e-01 | 100.0% | 69.6% |
| 4bmoA00 | 1.10.620.20 | Mainly Alpha › Orthogonal Bundle › Ribonucleotide Reductase, subunit A › Ribonucleotide Reductase, subunit A | 0.90 | 87.0 | 7.08e-01 | 100.0% | 69.3% |
| 2rccA01 | 1.10.620.20 | Mainly Alpha › Orthogonal Bundle › Ribonucleotide Reductase, subunit A › Ribonucleotide Reductase, subunit A | 0.90 | 87.0 | 7.39e-01 | 100.0% | 76.8% |
| 1h0oA00 | 1.10.620.20 | Mainly Alpha › Orthogonal Bundle › Ribonucleotide Reductase, subunit A › Ribonucleotide Reductase, subunit A | 0.90 | 87.0 | 7.11e-01 | 100.0% | 67.0% |
| 4a5dB00 | 1.10.620.20 | Mainly Alpha › Orthogonal Bundle › Ribonucleotide Reductase, subunit A › Ribonucleotide Reductase, subunit A | 0.90 | 81.0 | 7.20e-01 | 100.0% | 69.0% |
| 3bt5A00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.74 | 60.0 | 6.36e-01 | 83.7% | 100.0% |
| 1yjgA00 | 1.20.120.240 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Lipoprotein, type 6 | 0.70 | 46.0 | 4.88e-01 | 82.6% | 72.6% |
| 3fseB02 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.70 | 56.0 | 6.14e-01 | 85.5% | 100.0% |
| 3ajmB02 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.69 | 37.0 | 4.21e-01 | 79.7% | 66.9% |
| 2rbdA01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.69 | 58.0 | 6.19e-01 | 87.2% | 100.0% |
| 1sziA02 | 1.20.120.340 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Flagellar protein FliS | 0.66 | 39.0 | 4.35e-01 | 84.3% | 73.0% |
| 2qzcA00 | 1.20.910.10 | Mainly Alpha › Up-down Bundle › Heme Oxygenase; Chain A › Heme oxygenase-like | 0.66 | 50.0 | 4.72e-01 | 79.7% | 71.3% |
| 4omfA00 | 1.10.645.10 | Mainly Alpha › Orthogonal Bundle › Cytochrome-c3 Hydrogenase; chain B › Cytochrome-c3 Hydrogenase, chain B | 0.64 | 42.0 | 3.22e-01 | 82.0% | 29.6% |
| 4k0dA00 | 1.20.120.1730 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.63 | 41.0 | 4.43e-01 | 87.2% | 76.9% |
| 2wdqC00 | 1.20.1300.10 | Mainly Alpha › Up-down Bundle › 3 helical TM bundles of succinate and fumarate reductases › Fumarate reductase/succinate dehydrogenase, transmembrane subunit | 0.63 | 28.0 | 3.35e-01 | 100.0% | 58.7% |
| 6gy8A01 | 1.20.1170.10 | Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › | 0.60 | 53.0 | 4.22e-01 | 93.0% | 88.0% |
| 3l39A01 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.60 | 43.0 | 4.15e-01 | 73.8% | 91.0% |
| 2yfaA02 | 1.20.1440.210 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › | 0.60 | 40.0 | 4.68e-01 | 96.5% | 100.0% |
| 1m56C02 | 1.20.120.80 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c oxidase, subunit III, four-helix bundle | 0.59 | 50.0 | 4.79e-01 | 99.4% | 78.1% |
| 4nwpD00 | 1.20.1200.10 | Mainly Alpha › Up-down Bundle › Hypothetical Protein Ta1238; Chain: A; › Cobalamin adenosyltransferase-like | 0.59 | 47.0 | 5.01e-01 | 83.1% | 98.0% |
| 2iiuA00 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.58 | 45.0 | 4.25e-01 | 97.1% | 67.3% |
| 1aepA00 | 1.20.120.20 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein | 0.58 | 37.0 | 3.92e-01 | 95.3% | 70.6% |
| 1t98A02 | 1.20.58.590 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Chromosome partition protein MukF, middle domain | 0.58 | 44.0 | 4.50e-01 | 85.5% | 82.2% |
| 3caxA01 | 1.20.120.520 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › nmb1532 protein domain like | 0.58 | 48.0 | 4.38e-01 | 88.4% | 68.2% |
| 4yonA01 | 1.20.900.10 | Mainly Alpha › Up-down Bundle › Dbl Homology Domain; Chain A › Dbl homology (DH) domain | 0.58 | 46.0 | 4.27e-01 | 83.7% | 97.2% |
| 6grjB01 | 1.20.1170.10 | Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › | 0.57 | 52.0 | 4.19e-01 | 96.5% | 86.9% |
| 6h2dS01 | 1.20.1170.10 | Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › | 0.56 | 50.0 | 4.59e-01 | 95.3% | 93.7% |
| 3x0uB01 | 1.20.190.10 | Mainly Alpha › Up-down Bundle › Delta-Endotoxin; domain 1 › Pesticidal crystal protein, N-terminal domain | 0.56 | 44.0 | 3.95e-01 | 98.8% | 58.8% |
| 8bb6A01 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.53 | 44.0 | 3.20e-01 | 86.6% | 87.8% |
| 1r8iA00 | 1.20.58.430 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Type IV secretion system, VirB5-domain | 0.52 | 42.0 | 4.09e-01 | 84.3% | 95.2% |
| 1i4dA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.52 | 42.0 | 4.09e-01 | 84.3% | 97.9% |
| 3cazB00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.51 | 40.0 | 3.74e-01 | 81.4% | 89.5% |
| 3vkhA11 | 1.20.920.20 | Mainly Alpha › Up-down Bundle › Histone Acetyltransferase; Chain A › | 0.51 | 37.0 | 3.06e-01 | 92.4% | 40.4% |
| 3mzvA00 | 1.10.600.10 | Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase | 0.51 | 40.0 | 3.30e-01 | 83.1% | 100.0% |
| 2ficB00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.51 | 39.0 | 3.72e-01 | 80.2% | 91.5% |
ECOD (37)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2388926 | 150.1.2.1 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Heme oxygenase/Ribonucleotide reductase › Ribonuc_red_sm | 0.99 | 98.0 | 7.74e-01 | 100.0% | 65.3% |
| 5009513 | 150.1.2.1 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Heme oxygenase/Ribonucleotide reductase › Ribonuc_red_sm | 0.92 | 89.0 | 6.98e-01 | 100.0% | 63.1% |
| 436631 | 150.1.2.1 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Heme oxygenase/Ribonucleotide reductase › Ribonuc_red_sm | 0.92 | 89.0 | 6.74e-01 | 100.0% | 64.2% |
| 1726039 | 150.1.2.1 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Heme oxygenase/Ribonucleotide reductase › Ribonuc_red_sm | 0.92 | 89.0 | 6.81e-01 | 100.0% | 66.7% |
| 5009507 | 150.1.2.1 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Heme oxygenase/Ribonucleotide reductase › Ribonuc_red_sm | 0.92 | 88.0 | 6.90e-01 | 100.0% | 62.8% |
| 4603349 | 150.1.2.1 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Heme oxygenase/Ribonucleotide reductase › Ribonuc_red_sm | 0.91 | 89.0 | 6.70e-01 | 100.0% | 54.6% |
| 4267558 | 150.1.2.1 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Heme oxygenase/Ribonucleotide reductase › Ribonuc_red_sm | 0.91 | 88.0 | 6.92e-01 | 100.0% | 63.0% |
| 56518 | 150.1.2.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Heme oxygenase/Ribonucleotide reductase | 0.91 | 88.0 | 6.77e-01 | 100.0% | 66.7% |
| 5009559 | 150.1.2.1 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Heme oxygenase/Ribonucleotide reductase › Ribonuc_red_sm | 0.91 | 88.0 | 7.02e-01 | 100.0% | 66.2% |
| 3470297 | 150.1.2.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Heme oxygenase/Ribonucleotide reductase | 0.91 | 88.0 | 6.79e-01 | 100.0% | 57.6% |
| 3274715 | 150.1.2.1 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Heme oxygenase/Ribonucleotide reductase › Ribonuc_red_sm | 0.90 | 76.0 | 6.91e-01 | 86.0% | 78.6% |
| 56563 | 150.1.2.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Heme oxygenase/Ribonucleotide reductase | 0.90 | 87.0 | 7.11e-01 | 100.0% | 68.0% |
| 151585 | 150.1.2.1 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Heme oxygenase/Ribonucleotide reductase › Ribonuc_red_sm | 0.89 | 86.0 | 7.21e-01 | 100.0% | 72.0% |
| 1684591 | 150.1.2.1 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Heme oxygenase/Ribonucleotide reductase › Ribonuc_red_sm | 0.89 | 85.0 | 6.95e-01 | 100.0% | 70.0% |
| 2846952 | 150.1.2.1 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Heme oxygenase/Ribonucleotide reductase › Ribonuc_red_sm | 0.89 | 85.0 | 6.74e-01 | 100.0% | 61.7% |
| 2391405 | 150.1.2.1 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Heme oxygenase/Ribonucleotide reductase › Ribonuc_red_sm | 0.88 | 85.0 | 6.72e-01 | 100.0% | 61.5% |
| 3957842 | 150.1.2.10 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Heme oxygenase/Ribonucleotide reductase › AurF | 0.81 | 77.0 | 6.27e-01 | 100.0% | 68.5% |
| 3727197 | 5069.1.1.7 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › Cytochrom_B561 | 0.67 | 41.0 | 4.13e-01 | 84.3% | 60.0% |
| 3623633 | 633.21.1.0 ↗ | alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 | 0.66 | 42.0 | 4.61e-01 | 83.1% | 76.6% |
| 3585044 | 601.1.1.4 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › VBS | 0.64 | 38.0 | 3.98e-01 | 82.6% | 62.6% |
| 2492086 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.64 | 43.0 | 4.65e-01 | 83.1% | 79.6% |
| 3917162 | 150.1.1.36 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › Otopetrin | 0.62 | 47.0 | 4.49e-01 | 79.7% | 83.9% |
| 3236500 | 174.1.1.1 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin | 0.61 | 45.0 | 5.02e-01 | 100.0% | 95.6% |
| 3638405 | 633.21.1.0 ↗ | alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 | 0.61 | 48.0 | 4.90e-01 | 80.8% | 100.0% |
| 3616821 | 633.21.1.0 ↗ | alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 | 0.61 | 43.0 | 4.94e-01 | 100.0% | 96.2% |
| 3655954 | 5050.1.1.2 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › PTR2 | 0.61 | 44.0 | 3.93e-01 | 73.8% | 93.3% |
| 3231853 | 174.1.1.13 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › DUF2700 | 0.61 | 43.0 | 5.00e-01 | 99.4% | 100.0% |
| 3888824 | 601.1.2.11 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › CD20 | 0.60 | 45.0 | 4.82e-01 | 98.8% | 88.7% |
| 3933806 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.60 | 44.0 | 4.98e-01 | 99.4% | 100.0% |
| 3621306 | 150.1.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin | 0.57 | 44.0 | 4.89e-01 | 98.8% | 100.0% |
| 3580885 | 601.4.1.12 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains › DNA_repr_REX1B | 0.56 | 35.0 | 3.84e-01 | 76.2% | 73.8% |
| 3616343 | 601.1.1.97 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › DNA_repr_REX1B | 0.56 | 35.0 | 3.90e-01 | 76.2% | 79.3% |
| 3475773 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.54 | 40.0 | 2.99e-01 | 75.6% | 34.7% |
| 5005400 | 5069.1.1.3 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › Cyt_bd_oxida_I | 0.53 | 37.0 | 3.77e-01 | 82.6% | 72.7% |
| 3184974 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.51 | 37.0 | 3.26e-01 | 73.8% | 70.0% |
| 4967542 | 1075.5.1.0 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter | 0.51 | 37.0 | 3.28e-01 | 75.0% | 85.2% |
| 4438378 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.50 | 36.0 | 3.52e-01 | 73.8% | 82.6% |
D2
medium
residues 106-129_197-281
Domain cluster:
rep: IMGVR_UViG_3300032296_002551-3300032296-Ga0335303_15791441__D38-122