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IMGVR_UViG_2513237066_000002-2513237066-2513474721
Arc-VirIMGVR_UViG_2513237066_000002-2513237066-2513474721
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
medium
residues 1-90
D2
medium
residues 91-207_328-402
Domain cluster:
representative
CATH (14)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3cxbA03 | 1.10.1740.30 | Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › Secreted effector protein SifA helical domain | 0.66 | 23.0 | 3.47e-01 | 70.3% | 72.8% |
| 1s35A02 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.61 | 32.0 | 3.99e-01 | 98.4% | 83.6% |
| 2oexA01 | 1.20.120.560 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › alix/aip1 in complex with the ypdl late domain | 0.61 | 33.0 | 3.77e-01 | 87.0% | 69.2% |
| 2yfaB01 | 1.20.1440.210 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › | 0.59 | 28.0 | 3.44e-01 | 99.0% | 68.1% |
| 3mpiA01 | 1.10.540.10 | Mainly Alpha › Orthogonal Bundle › Butyryl-Coa Dehydrogenase, subunit A; domain 1 › Acyl-CoA dehydrogenase/oxidase, N-terminal domain | 0.58 | 23.0 | 2.85e-01 | 98.4% | 54.5% |
| 2oduA02 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.57 | 30.0 | 3.86e-01 | 99.0% | 89.5% |
| 6e1kA01 | 1.10.287.70 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.57 | 34.0 | 4.29e-01 | 86.5% | 99.1% |
| 3ck6C02 | 1.20.58.340 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region | 0.57 | 31.0 | 3.75e-01 | 99.0% | 81.5% |
| 2v0xA01 | 1.10.287.3160 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.56 | 33.0 | 3.55e-01 | 86.5% | 65.5% |
| 3p5pA03 | 1.10.600.10 | Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase | 0.53 | 44.0 | 3.73e-01 | 85.9% | 77.4% |
| 1wrdA00 | 1.20.58.160 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.53 | 26.0 | 3.37e-01 | 99.0% | 85.7% |
| 1cnt200 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.52 | 34.0 | 4.05e-01 | 81.8% | 97.7% |
| 1oxjA02 | 1.25.40.170 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Smaug, PHAT domain | 0.51 | 24.0 | 3.02e-01 | 98.4% | 71.6% |
| 4j05A00 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.50 | 39.0 | 2.95e-01 | 96.4% | 36.3% |
ECOD (2)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3276237 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.54 | 32.0 | 3.46e-01 | 95.3% | 66.9% |
| 4933354 | 3755.3.1.637 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › DUF7121 | 0.52 | 32.0 | 2.99e-01 | 93.2% | 47.9% |
D3
medium
residues 208-327
Domain cluster:
representative
CATH (2)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3spcA02 | 1.10.287.70 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.54 | 36.0 | 3.54e-01 | 74.2% | 63.8% |
| 1rh5A00 | 1.10.3370.10 | Mainly Alpha › Orthogonal Bundle › Preprotein translocase SecY subunit › SecY subunit domain | 0.51 | 44.0 | 3.09e-01 | 96.7% | 81.7% |
D4
medium
residues 663-764
Domain cluster:
representative
CATH (27)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3h36A00 | 1.10.10.400 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Polyribonucleotide nucleotidyltransferase, RNA-binding domain | 0.69 | 45.0 | 5.09e-01 | 87.3% | 87.2% |
| 2rt6A00 | 1.20.1270.340 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.64 | 36.0 | 3.68e-01 | 85.3% | 57.1% |
| 4cs9B02 | 1.20.120.1350 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Pneumovirus matrix protein 2 (M2), zinc-binding domain | 0.62 | 33.0 | 3.32e-01 | 90.2% | 46.7% |
| 1fftC00 | 1.20.120.80 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c oxidase, subunit III, four-helix bundle | 0.62 | 50.0 | 4.08e-01 | 86.3% | 90.8% |
| 4l0fA00 | 1.10.630.10 | Mainly Alpha › Orthogonal Bundle › Cytochrome p450 › Cytochrome P450 | 0.60 | 47.0 | 3.11e-01 | 85.3% | 77.8% |
| 5awwY00 | 1.10.3370.10 | Mainly Alpha › Orthogonal Bundle › Preprotein translocase SecY subunit › SecY subunit domain | 0.59 | 51.0 | 3.46e-01 | 100.0% | 32.3% |
| 1yozA00 | 1.10.3200.10 | Mainly Alpha › Orthogonal Bundle › Hypothetical protein af0941 › AF0941-like | 0.58 | 42.0 | 4.11e-01 | 86.3% | 68.1% |
| 1sumB01 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.58 | 45.0 | 4.43e-01 | 82.4% | 77.6% |
| 3lsjA02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.57 | 50.0 | 4.39e-01 | 100.0% | 64.7% |
| 5u56A02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.57 | 42.0 | 4.12e-01 | 84.3% | 71.4% |
| 1bf5A01 | 1.20.1050.20 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › STAT transcription factor, all-alpha domain | 0.57 | 45.0 | 3.77e-01 | 83.3% | 70.2% |
| 4nuuB02 | 1.20.58.830 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.57 | 46.0 | 4.30e-01 | 86.3% | 87.0% |
| 4ymuD00 | 1.10.3720.10 | Mainly Alpha › Orthogonal Bundle › MetI-like fold › MetI-like | 0.56 | 47.0 | 3.74e-01 | 92.2% | 60.9% |
| 2ra1A01 | 1.20.58.790 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.56 | 42.0 | 4.31e-01 | 92.2% | 81.6% |
| 5nl6B01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.56 | 44.0 | 4.23e-01 | 85.3% | 78.5% |
| 1y1uA01 | 1.20.1050.20 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › STAT transcription factor, all-alpha domain | 0.55 | 43.0 | 3.47e-01 | 82.4% | 48.7% |
| 1uurA01 | 1.20.58.240 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › STAT; domain 1 | 0.54 | 42.0 | 4.10e-01 | 83.3% | 85.5% |
| 4hehA01 | 1.10.1240.10 | Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › Methionine synthase domain | 0.53 | 33.0 | 3.56e-01 | 86.3% | 74.7% |
| 8sbeA02 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.53 | 45.0 | 3.70e-01 | 93.1% | 50.8% |
| 3rv0C02 | 1.10.1520.10 | Mainly Alpha › Orthogonal Bundle › Ribonuclease iii, N-terminal Endonuclease Domain; Chain A › Ribonuclease III domain | 0.53 | 44.0 | 3.93e-01 | 91.2% | 86.8% |
| 8itfR01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.53 | 47.0 | 3.43e-01 | 98.0% | 87.9% |
| 3ck6C02 | 1.20.58.340 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region | 0.53 | 42.0 | 3.98e-01 | 84.3% | 75.6% |
| 2ntxA02 | 1.20.58.1310 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › PRONE domain, subdomain 2 | 0.53 | 32.0 | 3.22e-01 | 90.2% | 57.3% |
| 1ylmA00 | 1.20.120.580 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › bsu32300-like | 0.51 | 46.0 | 4.10e-01 | 98.0% | 78.2% |
| 2v0xA01 | 1.10.287.3160 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.51 | 39.0 | 3.28e-01 | 79.4% | 66.7% |
| 2yksA02 | 1.20.58.390 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Neurotransmitter-gated ion-channel transmembrane domain | 0.51 | 45.0 | 4.34e-01 | 100.0% | 96.6% |
| 2r40D00 | 1.10.565.10 | Mainly Alpha › Orthogonal Bundle › Retinoid X Receptor › Retinoid X Receptor | 0.51 | 44.0 | 3.44e-01 | 98.0% | 49.4% |
ECOD (24)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3401287 | 603.2.1.12 ↗ | alpha bundles › STAT-like › STAT › STAT › 7tm_7 | 0.67 | 50.0 | 3.29e-01 | 78.4% | 63.1% |
| 3583518 | 109.4.1.1400 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PF27614, PF30377 | 0.66 | 52.0 | 3.41e-01 | 85.3% | 27.8% |
| 3799208 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.65 | 52.0 | 3.38e-01 | 85.3% | 27.2% |
| 3563871 | 603.1.1.121 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › PF30821 | 0.64 | 51.0 | 4.97e-01 | 87.3% | 96.5% |
| 4026675 | 603.1.1.172 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › DUF1617 | 0.61 | 46.0 | 4.46e-01 | 84.3% | 69.6% |
| 3210369 | 603.1.1.108 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › PF27599 | 0.60 | 43.0 | 4.00e-01 | 84.3% | 59.2% |
| 3389029 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.60 | 46.0 | 4.40e-01 | 80.4% | 73.9% |
| 3726384 | 604.4.1.0 ↗ | alpha bundles › Spectrin repeat-like › Alpha-hemoglobin stabilizing protein AHSP › Alpha-hemoglobin stabilizing protein AHSP | 0.58 | 39.0 | 4.12e-01 | 82.4% | 77.8% |
| 5000698 | 604.38.1.0 ↗ | alpha bundles › Spectrin repeat-like › Legionella effector SdeA 3-helical bundle › Legionella effector SdeA 3-helical bundle | 0.58 | 39.0 | 3.89e-01 | 83.3% | 65.7% |
| 4676221 | 1188.1.1.3 ↗ | alpha bundles › ZIP zinc transporter › ZIP zinc transporter › ZIP zinc transporter › Mntp | 0.57 | 43.0 | 3.63e-01 | 100.0% | 44.7% |
| 4195230 | 150.1.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin | 0.57 | 43.0 | 4.10e-01 | 80.4% | 88.3% |
| 5083475 | 4121.1.1.1 ↗ | a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like › CorA | 0.57 | 45.0 | 3.30e-01 | 85.3% | 36.7% |
| 3402945 | 4953.1.1.0 ↗ | beta barrels › L-aspartase C-terminal domain-like › L-aspartase C-terminal domain-like › L-aspartase C-terminal domain-like | 0.56 | 39.0 | 3.86e-01 | 88.2% | 66.4% |
| 3923226 | 5001.1.1.1 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 | 0.56 | 50.0 | 3.60e-01 | 100.0% | 83.8% |
| 4014747 | 4163.1.2.1 ↗ | alpha bundles › GINS helical bundle-like › GINS helical bundle-like › PSF2 C-terminal domain-like › Sld5 | 0.56 | 38.0 | 3.58e-01 | 70.6% | 72.8% |
| 3786522 | 604.6.1.22 ↗ | alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain › EMC4 | 0.55 | 41.0 | 4.09e-01 | 86.3% | 73.6% |
| 4962867 | 1075.3.1.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC importer transmembrane domain fold › Type I ABC importer transmembrane domain fold › BPD_transp_1 | 0.55 | 44.0 | 3.38e-01 | 87.3% | 79.2% |
| 3269429 | 603.2.1.2 ↗ | alpha bundles › STAT-like › STAT › STAT › Dict-STAT-coil | 0.55 | 48.0 | 4.58e-01 | 95.1% | 82.6% |
| 3190748 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.55 | 47.0 | 3.56e-01 | 93.1% | 40.8% |
| 4598870 | 5001.1.1.1 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 | 0.55 | 48.0 | 3.53e-01 | 100.0% | 87.5% |
| 4008711 | 1075.3.1.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC importer transmembrane domain fold › Type I ABC importer transmembrane domain fold › BPD_transp_1 | 0.55 | 42.0 | 3.38e-01 | 85.3% | 65.3% |
| 3272245 | 4121.1.1.1 ↗ | a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like › CorA | 0.54 | 38.0 | 2.82e-01 | 72.5% | 42.2% |
| 3812000 | 7023.1.1.3 ↗ | alpha bundles › helical ridge domain of D-alanyl transfer protein › helical ridge domain of D-alanyl transfer protein › helical ridge domain of D-alanyl transfer protein › MBOAT_2 | 0.54 | 48.0 | 4.51e-01 | 100.0% | 87.2% |
| 4927356 | 192.15.1.0 ↗ | alpha bundles › Long alpha-hairpin › Endosomal sorting complex assembly domains › Endosomal sorting complex assembly domains | 0.53 | 39.0 | 3.88e-01 | 78.4% | 74.3% |