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IMGVR_UViG_2529292733_000001-2529292733-2529763349
Arc-VirIMGVR_UViG_2529292733_000001-2529292733-2529763349
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 7-188
Domain cluster:
representative
CATH (41)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4gnkE00 | 1.20.1230.10 | Mainly Alpha › Up-down Bundle › Phospholipase C Beta; Chain: A › Phospholipase C beta, distal C-terminal domain | 0.67 | 47.0 | 4.31e-01 | 71.4% | 92.3% |
| 2oerA00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.66 | 42.0 | 4.31e-01 | 90.7% | 63.7% |
| 3snhA02 | 1.20.120.1240 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Dynamin, middle domain | 0.66 | 60.0 | 5.68e-01 | 100.0% | 91.2% |
| 3ljbA00 | 1.20.120.1240 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Dynamin, middle domain | 0.65 | 59.0 | 5.57e-01 | 100.0% | 88.1% |
| 4bejB02 | 1.20.120.1240 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Dynamin, middle domain | 0.64 | 58.0 | 5.43e-01 | 100.0% | 87.9% |
| 6dewA01 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.63 | 39.0 | 3.92e-01 | 80.8% | 58.4% |
| 1jadA00 | 1.20.1230.10 | Mainly Alpha › Up-down Bundle › Phospholipase C Beta; Chain: A › Phospholipase C beta, distal C-terminal domain | 0.63 | 47.0 | 4.27e-01 | 76.4% | 94.2% |
| 1vi0A02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.63 | 40.0 | 4.42e-01 | 84.6% | 78.6% |
| 4rfsS00 | 1.10.1760.20 | Mainly Alpha › Orthogonal Bundle › Arp2/3 complex 21 kDa subunit ARPC3 › | 0.62 | 41.0 | 4.12e-01 | 84.6% | 64.2% |
| 4f4cA01 | 1.20.1560.10 | Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain | 0.60 | 55.0 | 3.63e-01 | 97.8% | 71.7% |
| 4fp4A00 | 1.10.600.10 | Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase | 0.59 | 40.0 | 3.62e-01 | 85.7% | 50.6% |
| 4oydB00 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.59 | 38.0 | 4.60e-01 | 74.7% | 99.1% |
| 3v0aB02 | 1.20.1120.10 | Mainly Alpha › Up-down Bundle › "Clostridium botulinum neurotoxin B, ""coiled-coil"" domain" › "Clostridium botulinum neurotoxin b, ""coiled-coil"" domain" | 0.59 | 44.0 | 3.60e-01 | 76.4% | 57.7% |
| 2lquA01 | 1.20.1420.40 | Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Decorin-binding protein | 0.58 | 36.0 | 3.84e-01 | 87.4% | 69.5% |
| 7cfmR01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.58 | 40.0 | 3.54e-01 | 86.3% | 47.5% |
| 2v0xA01 | 1.10.287.3160 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.58 | 33.0 | 3.45e-01 | 93.4% | 60.1% |
| 7powA01 | 1.20.120.1760 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › CDP-alcohol phosphotransferase transmembrane (TM) domain | 0.58 | 37.0 | 3.62e-01 | 93.4% | 58.1% |
| 4nn1A00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.57 | 39.0 | 3.81e-01 | 83.0% | 61.0% |
| 2gs4A00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.57 | 35.0 | 3.78e-01 | 84.1% | 69.6% |
| 3emlA01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.57 | 43.0 | 3.69e-01 | 84.6% | 49.3% |
| 3fmsA02 | 1.20.120.530 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › GntR ligand-binding domain-like | 0.56 | 42.0 | 4.77e-01 | 84.6% | 99.3% |
| 6q45G01 | 1.10.287.80 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ATP synthase, gamma subunit, helix hairpin domain | 0.56 | 29.0 | 3.20e-01 | 96.2% | 59.6% |
| 4kwaB00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.54 | 36.0 | 3.58e-01 | 91.2% | 62.0% |
| 7utzR02 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.54 | 43.0 | 3.78e-01 | 83.5% | 78.8% |
| 4cqiA00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.54 | 30.0 | 3.84e-01 | 89.0% | 92.5% |
| 8ipqB01 | 1.20.1560.10 | Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain | 0.54 | 42.0 | 3.58e-01 | 80.8% | 100.0% |
| 4xt1A00 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.54 | 38.0 | 3.24e-01 | 82.4% | 44.0% |
| 2e87A01 | 1.20.120.1190 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.53 | 40.0 | 4.19e-01 | 87.9% | 87.5% |
| 2z73B01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.53 | 41.0 | 3.32e-01 | 84.1% | 41.6% |
| 6ko5A02 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.53 | 41.0 | 3.53e-01 | 84.6% | 50.3% |
| 4jgwA01 | 1.20.870.10 | Mainly Alpha › Up-down Bundle › Son of sevenless (SoS) protein; Chain S, domain 1 › Son of sevenless (SoS) protein Chain: S domain 1 | 0.53 | 24.0 | 2.64e-01 | 91.8% | 48.7% |
| 8etcb01 | 1.20.120.1190 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.52 | 38.0 | 4.20e-01 | 85.7% | 93.8% |
| 2nrjA01 | 1.20.1170.10 | Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › | 0.52 | 42.0 | 3.45e-01 | 84.1% | 90.0% |
| 7dl9A01 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.52 | 35.0 | 3.43e-01 | 84.6% | 61.9% |
| 7xk2R01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.52 | 38.0 | 3.43e-01 | 86.3% | 52.5% |
| 2genA00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.52 | 34.0 | 3.40e-01 | 91.8% | 62.8% |
| 6me6B02 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.51 | 38.0 | 3.33e-01 | 80.8% | 48.9% |
| 2v6kA02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.51 | 32.0 | 3.70e-01 | 89.0% | 86.2% |
| 1sziA02 | 1.20.120.340 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Flagellar protein FliS | 0.51 | 36.0 | 4.08e-01 | 89.0% | 96.4% |
| 3syvA01 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.51 | 39.0 | 3.51e-01 | 79.1% | 87.8% |
| 3kkdA00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.50 | 36.0 | 3.51e-01 | 92.3% | 66.2% |
ECOD (41)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3621548 | 5079.1.1.1 ↗ | alpha duplicates or obligate multimers › Magnesium transporter MgtE membrane domain › Magnesium transporter MgtE membrane domain › Magnesium transporter MgtE membrane domain › MgtE | 0.69 | 58.0 | 5.49e-01 | 95.1% | 74.4% |
| 4667858 | 6108.1.1.1 ↗ | alpha bundles › Middle and GTPase effector domains in dynamin-related proteins › Middle and GTPase effector domains in dynamin-related proteins › Middle and GTPase effector domains in dynamin-related proteins › Dynamin_M,GED | 0.68 | 62.0 | 5.17e-01 | 100.0% | 69.1% |
| 5050120 | 5079.1.1.1 ↗ | alpha duplicates or obligate multimers › Magnesium transporter MgtE membrane domain › Magnesium transporter MgtE membrane domain › Magnesium transporter MgtE membrane domain › MgtE | 0.68 | 53.0 | 5.39e-01 | 92.9% | 82.7% |
| 2080227 | 6108.1.1.1 ↗ | alpha bundles › Middle and GTPase effector domains in dynamin-related proteins › Middle and GTPase effector domains in dynamin-related proteins › Middle and GTPase effector domains in dynamin-related proteins › Dynamin_M,GED | 0.66 | 46.0 | 4.85e-01 | 70.9% | 84.2% |
| 4580144 | 1075.1.2.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › MacB transmembrane domain › FtsX | 0.65 | 49.0 | 4.92e-01 | 79.1% | 76.3% |
| 3607500 | 310.2.1.0 ↗ | a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF | 0.63 | 44.0 | 4.39e-01 | 72.5% | 68.6% |
| 3743731 | 3615.1.1.0 ↗ | alpha bundles › Bacterial dynamin-like protein helical domain › Bacterial dynamin-like protein helical domain › Bacterial dynamin-like protein helical domain | 0.61 | 53.0 | 5.07e-01 | 96.2% | 80.0% |
| 4422739 | 5045.1.1.1 ↗ | alpha bundles › F1F0 ATP synthase subunit A › F1F0 ATP synthase subunit A › F1F0 ATP synthase subunit A › ATP-synt_A | 0.61 | 49.0 | 4.54e-01 | 91.2% | 67.1% |
| 4656035 | 5001.1.1.9 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › TAS2R | 0.61 | 47.0 | 4.02e-01 | 84.6% | 49.0% |
| 3958112 | 1075.1.2.0 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › MacB transmembrane domain | 0.59 | 48.0 | 4.39e-01 | 90.1% | 64.1% |
| 4581508 | 601.19.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Apolipoprotein › Apolipoprotein › Apolipoprotein | 0.59 | 54.0 | 5.14e-01 | 99.5% | 90.0% |
| 3511834 | 1075.1.2.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › MacB transmembrane domain › FtsX | 0.58 | 41.0 | 4.71e-01 | 75.3% | 100.0% |
| 3881581 | 310.2.1.11 ↗ | a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF › DUF4456 | 0.57 | 41.0 | 4.31e-01 | 72.5% | 93.3% |
| 4931100 | 7064.1.1.1 ↗ | alpha bundles › Transmembrane domain of VIT1 › Transmembrane domain of VIT1 › Transmembrane domain of VIT1 › VIT1 | 0.57 | 45.0 | 4.54e-01 | 87.4% | 83.3% |
| 5030487 | 604.39.1.0 ↗ | alpha bundles › Spectrin repeat-like › S-component of energy-coupling factor (ECF) transporters › S-component of energy-coupling factor (ECF) transporters | 0.56 | 41.0 | 3.95e-01 | 96.2% | 64.3% |
| 3179380 | 5069.1.1.0 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes | 0.56 | 43.0 | 4.43e-01 | 83.0% | 84.0% |
| 4077080 | 5045.1.1.1 ↗ | alpha bundles › F1F0 ATP synthase subunit A › F1F0 ATP synthase subunit A › F1F0 ATP synthase subunit A › ATP-synt_A | 0.55 | 49.0 | 4.39e-01 | 95.6% | 69.4% |
| 4141759 | 5045.1.1.1 ↗ | alpha bundles › F1F0 ATP synthase subunit A › F1F0 ATP synthase subunit A › F1F0 ATP synthase subunit A › ATP-synt_A | 0.55 | 48.0 | 4.47e-01 | 93.4% | 74.3% |
| 4945433 | 5076.2.1.9 ↗ | alpha complex topology › Mitochondrial ADP/ATP carrier-like › Putative sulfate permease CysZ › Putative sulfate permease CysZ › Choline_transpo | 0.55 | 50.0 | 4.44e-01 | 99.5% | 89.4% |
| 4974383 | 1075.5.1.4 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › Polysacc_synt | 0.55 | 42.0 | 4.04e-01 | 91.8% | 69.8% |
| 3861789 | 5001.1.1.9 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › TAS2R | 0.54 | 43.0 | 3.57e-01 | 84.1% | 49.7% |
| 4218519 | 5045.1.1.1 ↗ | alpha bundles › F1F0 ATP synthase subunit A › F1F0 ATP synthase subunit A › F1F0 ATP synthase subunit A › ATP-synt_A | 0.54 | 46.0 | 4.30e-01 | 94.0% | 74.5% |
| 4032308 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.53 | 40.0 | 4.14e-01 | 80.2% | 82.9% |
| 5002996 | 1075.5.1.4 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › Polysacc_synt | 0.53 | 41.0 | 3.97e-01 | 92.3% | 71.2% |
| 5035080 | 5069.1.1.0 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes | 0.53 | 33.0 | 3.55e-01 | 84.6% | 71.6% |
| 3989110 | 1075.5.1.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MatE | 0.53 | 42.0 | 4.07e-01 | 92.3% | 74.6% |
| 3463576 | 3684.1.1.2 ↗ | alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › BPS1 | 0.52 | 43.0 | 4.09e-01 | 87.4% | 75.9% |
| 3480000 | 5001.1.1.5 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_3 | 0.52 | 41.0 | 3.56e-01 | 84.6% | 54.9% |
| 3843924 | 5001.1.1.9 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › TAS2R | 0.52 | 40.0 | 3.44e-01 | 80.8% | 70.3% |
| 3279977 | 1075.5.1.0 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter | 0.52 | 39.0 | 3.72e-01 | 91.2% | 66.3% |
| 5028176 | 1075.5.1.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MatE | 0.52 | 41.0 | 3.55e-01 | 90.7% | 54.2% |
| 5035878 | 1075.5.1.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MatE | 0.52 | 41.0 | 3.91e-01 | 90.7% | 70.7% |
| 2671884 | 601.1.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › Vinculin | 0.52 | 36.0 | 3.88e-01 | 87.9% | 84.1% |
| 4952080 | 1075.5.1.0 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter | 0.52 | 39.0 | 3.81e-01 | 90.1% | 70.2% |
| 3589541 | 5082.1.1.1 ↗ | alpha bundles › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation efflux protein transmembrane domain-like › Cation_efflux | 0.51 | 34.0 | 3.42e-01 | 91.8% | 63.2% |
| 3618454 | 5001.1.1.5 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_3 | 0.51 | 40.0 | 3.64e-01 | 84.6% | 79.2% |
| 3964740 | 1075.5.1.12 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MurJ, Polysacc_synt_3 | 0.51 | 41.0 | 3.64e-01 | 91.8% | 58.1% |
| 4177736 | 1075.1.2.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › MacB transmembrane domain › FtsX | 0.50 | 45.0 | 4.35e-01 | 97.3% | 95.2% |
| 3691307 | 601.33.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › CHAD domain › CHAD domain | 0.50 | 43.0 | 4.14e-01 | 92.3% | 94.8% |
| 5059074 | 5076.2.1.18 ↗ | alpha complex topology › Mitochondrial ADP/ATP carrier-like › Putative sulfate permease CysZ › Putative sulfate permease CysZ › DUF6159 | 0.50 | 46.0 | 4.29e-01 | 97.8% | 96.8% |
| 5058663 | 1075.5.1.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MatE | 0.50 | 40.0 | 3.84e-01 | 90.7% | 71.4% |
D2
high
residues 194-274
Domain cluster:
rep: KT021004.1__ALA06374.1__P1312_001__00001__D177-245