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IMGVR_UViG_2554235482_000003-2554235482-2556119543

Arc-Vir

IMGVR_UViG_2554235482_000003-2554235482-2556119543

Identity

Kingdom:
archaea

Quality

83.3 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 20-79
PDB
Domain cluster: representative
CATH (77)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
5mc9A02 2.60.120.200 Mainly Beta › Sandwich › Jelly Rolls › 0.78 53.0 3.72e-01 81.7% 23.1%
1lf6A01 2.70.98.10 Mainly Beta › Distorted Sandwich › Beta-galactosidase; Chain A, domain 5 › 0.70 62.0 4.03e-01 100.0% 32.2%
1ulvA01 2.70.98.10 Mainly Beta › Distorted Sandwich › Beta-galactosidase; Chain A, domain 5 › 0.70 62.0 4.02e-01 100.0% 32.0%
4orlA00 3.10.450.50 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.70 62.0 5.09e-01 100.0% 94.5%
6gh3A01 2.70.98.40 Mainly Beta › Distorted Sandwich › Beta-galactosidase; Chain A, domain 5 › Glycoside hydrolase, family 65, N-terminal domain 0.69 61.0 3.85e-01 100.0% 32.7%
2xn2A03 2.60.40.1180 Mainly Beta › Sandwich › Immunoglobulin-like › Golgi alpha-mannosidase II 0.69 55.0 4.73e-01 88.3% 96.9%
3en8A01 3.10.450.50 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.68 60.0 4.91e-01 100.0% 91.1%
5w8mA00 3.60.21.10 Alpha Beta › 4-Layer Sandwich › Purple Acid Phosphatase; chain A, domain 2 › Metallo-dependent phosphatases 0.68 58.0 4.13e-01 100.0% 85.2%
3ghjA00 3.10.180.10 Alpha Beta › Roll › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase; domain 1 › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1 0.67 52.0 4.20e-01 96.7% 44.0%
2xlpB01 3.50.50.60 Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain 0.67 47.0 2.89e-01 73.3% 43.8%
1omoA01 3.30.1780.10 Alpha Beta › 2-Layer Sandwich › ornithine cyclodeaminase, domain 1 › ornithine cyclodeaminase, domain 1 0.67 52.0 3.89e-01 85.0% 40.3%
4exrA01 3.10.450.40 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.66 57.0 5.14e-01 100.0% 70.4%
2r5vB02 3.10.180.10 Alpha Beta › Roll › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase; domain 1 › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1 0.66 58.0 4.09e-01 100.0% 37.9%
2x9oA00 3.40.1500.20 Alpha Beta › 3-Layer(aba) Sandwich › oxygen-dependent coproporphyrinogen oxidase › 0.66 57.0 3.87e-01 100.0% 30.0%
3kf3A02 2.60.120.560 Mainly Beta › Sandwich › Jelly Rolls › Exo-inulinase; domain 1 0.64 50.0 3.60e-01 86.7% 32.2%
2p25A01 3.10.180.10 Alpha Beta › Roll › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase; domain 1 › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1 0.63 56.0 4.42e-01 96.7% 52.1%
4hgzA02 2.20.25.570 Mainly Beta › Single Sheet › N-terminal domain of TfIIb › 0.63 46.0 4.63e-01 81.7% 78.3%
1jc4A00 3.10.180.10 Alpha Beta › Roll › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase; domain 1 › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1 0.63 54.0 4.16e-01 98.3% 51.7%
3pg7A02 2.30.29.30 Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 0.63 49.0 4.00e-01 88.3% 45.5%
3e3xA02 3.30.70.240 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.62 55.0 4.69e-01 100.0% 61.7%
2lexA00 2.20.25.80 Mainly Beta › Single Sheet › N-terminal domain of TfIIb › WRKY domain 0.62 51.0 5.03e-01 91.7% 87.3%
1uswA00 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.62 53.0 3.54e-01 98.3% 50.4%
1qhdA01 2.60.120.170 Mainly Beta › Sandwich › Jelly Rolls › 0.62 46.0 3.40e-01 81.7% 97.1%
3bxoA02 2.20.130.10 Mainly Beta › Single Sheet › S-adenosyl-L-methionine-dependent methyltransferases › CAC2371-like domains 0.62 47.0 4.74e-01 81.7% 88.1%
6w1kA01 3.10.180.50 Alpha Beta › Roll › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase; domain 1 › 0.62 53.0 3.48e-01 100.0% 43.1%
6bu2A00 3.10.180.10 Alpha Beta › Roll › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase; domain 1 › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1 0.62 52.0 4.02e-01 100.0% 46.7%
2fgeA01 3.30.830.10 Alpha Beta › 2-Layer Sandwich › Cytochrome Bc1 Complex; Chain A, domain 1 › Metalloenzyme, LuxS/M16 peptidase-like 0.62 50.0 3.35e-01 91.7% 88.0%
3nctA00 3.40.50.11880 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Plasmid SOS inhibition protein 0.61 52.0 4.03e-01 100.0% 42.3%
3e5dA00 3.10.180.10 Alpha Beta › Roll › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase; domain 1 › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1 0.61 52.0 4.13e-01 96.7% 49.6%
2rqxA00 2.40.50.650 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › 0.61 47.0 4.28e-01 83.3% 87.7%
4r80A00 3.10.450.630 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.61 53.0 4.95e-01 100.0% 82.9%
1plqA00 3.70.10.10 Alpha Beta › Box › Proliferating Cell Nuclear Antigen › 0.60 51.0 3.45e-01 100.0% 93.0%
1yemB00 2.40.320.10 Mainly Beta › Beta Barrel › Hypothetical Protein Pfu-838710-001 › Hypothetical Protein Pfu-838710-001 0.60 51.0 3.81e-01 100.0% 71.7%
3esiA00 3.10.129.10 Alpha Beta › Roll › Thiol Ester Dehydrase; Chain A › Hotdog Thioesterase 0.60 49.0 3.85e-01 88.3% 86.3%
3h0gH00 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.60 48.0 3.79e-01 88.3% 79.0%
3iujA02 2.130.10.120 Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › Prolyl oligopeptidase, N-terminal domain 0.60 50.0 3.22e-01 100.0% 17.9%
3d4eA01 3.30.1450.10 Alpha Beta › 2-Layer Sandwich › Beta-lactamase Inhibitory Protein; Chain:B, domain 1 › 0.60 48.0 4.35e-01 100.0% 65.5%
3hdjA01 3.30.1780.10 Alpha Beta › 2-Layer Sandwich › ornithine cyclodeaminase, domain 1 › ornithine cyclodeaminase, domain 1 0.60 49.0 3.79e-01 93.3% 47.9%
7obmA01 2.130.10.120 Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › Prolyl oligopeptidase, N-terminal domain 0.60 52.0 3.28e-01 100.0% 29.3%
3oa4A01 3.10.180.10 Alpha Beta › Roll › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase; domain 1 › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1 0.60 51.0 4.06e-01 100.0% 50.4%
3ndaA02 2.30.39.10 Mainly Beta › Roll › Alpha-1-antitrypsin; domain 1 › Alpha-1-antitrypsin, domain 1 0.60 48.0 3.84e-01 93.3% 72.7%
1k90A02 3.90.1760.10 Alpha Beta › Alpha-Beta Complex › Adenylylcyclase toxin fold › Anthrax toxin, edema factor, central domain 0.59 45.0 3.39e-01 100.0% 32.1%
3fljA00 3.10.450.50 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.59 49.0 3.91e-01 100.0% 70.9%
4hn7A00 2.40.50.650 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › 0.59 47.0 4.21e-01 86.7% 84.7%
3nybA02 3.30.460.10 Alpha Beta › 2-Layer Sandwich › Beta Polymerase; domain 2 › Beta Polymerase, domain 2 0.59 41.0 3.51e-01 78.3% 41.8%
5bv3D01 3.30.200.40 Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Scavenger mRNA decapping enzyme, N-terminal domain 0.59 48.0 3.97e-01 90.0% 83.9%
7ne4A01 2.130.10.120 Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › Prolyl oligopeptidase, N-terminal domain 0.59 51.0 3.21e-01 100.0% 24.3%
4exrA02 3.10.450.40 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.59 48.0 4.60e-01 98.3% 77.5%
3g7nB00 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.58 49.0 3.34e-01 100.0% 52.5%
2nwvA00 3.30.310.110 Alpha Beta › 2-Layer Sandwich › TATA-Binding Protein › XisI-like 0.58 47.0 4.01e-01 96.7% 56.2%
3zhaQ02 2.30.39.10 Mainly Beta › Roll › Alpha-1-antitrypsin; domain 1 › Alpha-1-antitrypsin, domain 1 0.58 50.0 3.90e-01 96.7% 67.9%
1attA01 2.30.39.10 Mainly Beta › Roll › Alpha-1-antitrypsin; domain 1 › Alpha-1-antitrypsin, domain 1 0.58 47.0 3.67e-01 93.3% 72.9%
1e5tA02 2.130.10.120 Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › Prolyl oligopeptidase, N-terminal domain 0.58 49.0 3.11e-01 100.0% 24.1%
3stoA02 2.30.39.10 Mainly Beta › Roll › Alpha-1-antitrypsin; domain 1 › Alpha-1-antitrypsin, domain 1 0.57 47.0 3.63e-01 93.3% 73.3%
2oq8A00 2.60.40.2930 Mainly Beta › Sandwich › Immunoglobulin-like › 0.57 48.0 3.71e-01 100.0% 56.0%
4zk3A02 2.30.39.10 Mainly Beta › Roll › Alpha-1-antitrypsin; domain 1 › Alpha-1-antitrypsin, domain 1 0.57 48.0 3.84e-01 96.7% 70.9%
1wz9A02 2.30.39.10 Mainly Beta › Roll › Alpha-1-antitrypsin; domain 1 › Alpha-1-antitrypsin, domain 1 0.57 48.0 3.72e-01 96.7% 70.4%
6qk7A01 2.130.10.10 Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › YVTN repeat-like/Quinoprotein amine dehydrogenase 0.57 49.0 3.13e-01 100.0% 18.2%
3pzfA01 2.30.39.10 Mainly Beta › Roll › Alpha-1-antitrypsin; domain 1 › Alpha-1-antitrypsin, domain 1 0.57 48.0 3.53e-01 100.0% 96.6%
1ugiD00 3.10.450.20 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › Bacteriophage PBS2, uracil-glycosylase inhibitor 0.56 48.0 4.39e-01 98.3% 87.8%
1uypA01 2.115.10.20 Mainly Beta › 5 Propeller › Tachylectin-2; Chain A › Glycosyl hydrolase domain; family 43 0.56 48.0 3.10e-01 100.0% 20.5%
5t5lA00 2.60.120.200 Mainly Beta › Sandwich › Jelly Rolls › 0.56 40.0 2.74e-01 76.7% 48.5%
1yr2A02 2.130.10.120 Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › Prolyl oligopeptidase, N-terminal domain 0.56 48.0 3.06e-01 100.0% 23.0%
3f40A00 3.10.450.50 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.56 46.0 3.91e-01 100.0% 89.2%
1o5yA00 3.10.690.10 Alpha Beta › Roll › Bifunctional nuclease domain › Bifunctional nuclease domain 0.55 39.0 3.05e-01 75.0% 32.9%
7bysA01 2.115.10.20 Mainly Beta › 5 Propeller › Tachylectin-2; Chain A › Glycosyl hydrolase domain; family 43 0.55 46.0 2.95e-01 93.3% 24.4%
3f8xB00 3.10.450.50 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.55 45.0 3.67e-01 100.0% 78.0%
4ftxB01 3.30.450.30 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › Dynein light chain 2a, cytoplasmic 0.55 42.0 3.47e-01 100.0% 42.2%
1y4wA01 2.115.10.20 Mainly Beta › 5 Propeller › Tachylectin-2; Chain A › Glycosyl hydrolase domain; family 43 0.55 48.0 2.97e-01 100.0% 17.2%
3sc7X01 2.115.10.20 Mainly Beta › 5 Propeller › Tachylectin-2; Chain A › Glycosyl hydrolase domain; family 43 0.55 48.0 2.99e-01 100.0% 18.8%
1e2rA02 2.140.10.20 Mainly Beta › 8 Propeller › Methanol Dehydrogenase; Chain A › C-terminal (heme d1) domain of cytochrome cd1-nitrite reductase 0.54 47.0 2.83e-01 100.0% 19.0%
2xklA00 2.40.128.20 Mainly Beta › Beta Barrel › Lipocalin › Calycin beta-barrel core domain 0.54 38.0 2.94e-01 75.0% 51.0%
6mlyB01 2.115.10.20 Mainly Beta › 5 Propeller › Tachylectin-2; Chain A › Glycosyl hydrolase domain; family 43 0.54 47.0 3.11e-01 100.0% 26.3%
2i5hA01 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.54 43.0 4.04e-01 86.7% 98.6%
3pieB05 2.30.30.30 Mainly Beta › Roll › SH3 type barrels. › 0.51 36.0 3.62e-01 78.3% 78.1%
1maiA00 2.30.29.30 Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) 0.50 36.0 2.97e-01 80.0% 38.7%
7bwcA01 2.115.10.20 Mainly Beta › 5 Propeller › Tachylectin-2; Chain A › Glycosyl hydrolase domain; family 43 0.50 41.0 2.69e-01 98.3% 23.8%
ECOD (93)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
5014253 243.3.1.0 a+b two layers › Cystatin-like › Cystatin/monellin › Cystatin/monellin 0.72 61.0 5.82e-01 100.0% 80.0%
4027680 241.15.1.2 a+b two layers › Type III secretory system chaperone-like › FP (Fbxo7/PI31) dimerization domain › FP (Fbxo7/PI31) dimerization domain › PI31_Prot_N 0.72 63.0 4.80e-01 100.0% 44.1%
5035423 295.1.1.0 a+b two layers › ssDNA-binding transcriptional regulator domain-like › ssDNA-binding transcriptional regulator domain › ssDNA-binding transcriptional regulator domain 0.72 50.0 4.49e-01 81.7% 51.8%
3401172 1116.1.1.1 a+b two layers › Polycystin-mucolipin domain › Polycystin-mucolipin domain › Polycystin-mucolipin domain › Polycystin_dom 0.70 61.0 4.15e-01 100.0% 80.0%
3242315 145.1.1.0 alpha arrays › F-box domain › F-box domain › F-box domain 0.70 52.0 5.42e-01 85.0% 89.1%
4996023 2.1.1.77 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › RNA_pol_RpbG 0.69 54.0 4.26e-01 83.3% 82.6%
4955671 7089.1.1.0 a+b two layers › Methane monooxygenase hydroxylase, MmoD › Methane monooxygenase hydroxylase, MmoD › Methane monooxygenase hydroxylase, MmoD 0.68 53.0 4.87e-01 85.0% 68.8%
5043413 4252.1.1.0 beta barrels › AttH-like › AttH-like › AttH-like 0.67 59.0 4.89e-01 100.0% 75.5%
1170463 243.3.1.3 a+b two layers › Cystatin-like › Cystatin/monellin › Cystatin/monellin › PepSY 0.66 57.0 4.94e-01 100.0% 62.6%
5019886 243.3.1.3 a+b two layers › Cystatin-like › Cystatin/monellin › Cystatin/monellin › PepSY 0.66 60.0 5.56e-01 100.0% 81.3%
3613801 5.1.2.0 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 5-bladed 0.66 59.0 3.60e-01 100.0% 21.9%
4955898 2.1.1.27 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › RNA_pol_Rpb8 0.66 52.0 4.20e-01 85.0% 80.9%
3579989 5.1.4.116 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › IKI3 0.65 59.0 3.60e-01 100.0% 19.2%
3947082 243.3.1.0 a+b two layers › Cystatin-like › Cystatin/monellin › Cystatin/monellin 0.64 56.0 4.95e-01 100.0% 67.8%
None 0.64 55.0 5.23e-01 100.0% 82.9%
3511321 5.1.4.298 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › Beta-prop_ELP1_1st, Beta-prop_ELP1_2nd 0.64 57.0 3.25e-01 100.0% 11.4%
4032029 243.1.1.0 a+b two layers › Cystatin-like › NTF2-like › NTF2-like 0.64 54.0 4.67e-01 95.0% 89.5%
3188039 2.1.1.27 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › RNA_pol_Rpb8 0.64 52.0 3.85e-01 88.3% 82.4%
3206031 708.1.1.0 beta complex topology › ETN0001 domain-like › ETN0001 domain-like › NAC/WRKY/GCM/WOPR domain 0.63 55.0 4.71e-01 100.0% 66.3%
5011042 3692.1.1.0 a+b two layers › Ornithine cyclodeaminase-like enzymes dimerization domain › Ornithine cyclodeaminase-like enzymes dimerization domain › Ornithine cyclodeaminase-like enzymes dimerization domain 0.63 51.0 4.01e-01 90.0% 44.6%
154755 4059.1.1.0 a+b complex topology › Serpins › Serpins › Serpins 0.63 50.0 3.09e-01 88.3% 48.5%
3979044 206.1.3.40 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › ATP-grasp › ATPgrasp_YheCD 0.63 46.0 3.13e-01 80.0% 23.5%
3509388 10.1.1.0 beta sandwiches › jelly-roll › Concanavalin A-like › Concanavalin A-like lectins/glucanases 0.63 51.0 3.04e-01 90.0% 17.7%
4948189 2.1.1.0 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein 0.63 49.0 3.88e-01 83.3% 80.5%
5012271 5.1.4.14 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › Peptidase_S9_N 0.63 55.0 3.50e-01 100.0% 19.0%
3578584 5.1.8.0 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › putative conserved lipoprotein NT01CX_1156 0.63 56.0 4.57e-01 100.0% 66.4%
3423079 5.1.4.231 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › FBA_3 0.62 48.0 3.07e-01 100.0% 16.5%
1160752 211.1.1.1 a+b two layers › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase › Glyoxalase 0.62 42.0 4.16e-01 73.3% 66.2%
4033429 243.3.1.3 a+b two layers › Cystatin-like › Cystatin/monellin › Cystatin/monellin › PepSY 0.62 53.0 4.82e-01 100.0% 71.2%
3804776 5.1.3.118 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed › FBA_3 0.62 55.0 3.47e-01 100.0% 23.9%
3738911 5.1.5.1 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 8-bladed › WD40 0.62 56.0 3.35e-01 100.0% 17.7%
3925780 5.1.4.14 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › Peptidase_S9_N 0.62 54.0 3.34e-01 100.0% 21.6%
3509217 11.10.1.0 beta sandwiches › Immunoglobulin-like beta-sandwich › TRAF domain-like › TRAF domain-like 0.61 47.0 3.64e-01 83.3% 54.1%
3551728 4059.1.1.1 a+b complex topology › Serpins › Serpins › Serpins › Serpin 0.61 49.0 2.99e-01 88.3% 50.1%
3809675 59.1.3.1 beta complex topology › triple barrel › triple barrel › RNA polymerase I subunits A49/A34.5 dimerization domains › RNA_pol_I_A49 0.61 52.0 4.25e-01 100.0% 84.2%
3547737 4059.1.1.1 a+b complex topology › Serpins › Serpins › Serpins › Serpin 0.61 49.0 3.03e-01 90.0% 49.3%
279848 4059.1.1.0 a+b complex topology › Serpins › Serpins › Serpins 0.61 48.0 2.98e-01 88.3% 49.6%
4426077 241.1.1.2 a+b two layers › Type III secretory system chaperone-like › Type III secretory system chaperone › Type III secretory system chaperone › Autophagy_act_C 0.60 52.0 3.95e-01 100.0% 38.7%
3199763 220.1.1.202 beta barrels › PH domain-like › PH domain-like › PH domain-like › PH_FT_N 0.60 51.0 4.10e-01 96.7% 86.4%
3962383 243.1.1.18 a+b two layers › Cystatin-like › NTF2-like › NTF2-like › SnoaL_2 0.60 52.0 4.18e-01 100.0% 85.6%
4262036 4059.1.1.1 a+b complex topology › Serpins › Serpins › Serpins › Serpin 0.60 48.0 3.00e-01 90.0% 47.4%
5045363 5.1.4.14 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › Peptidase_S9_N 0.60 51.0 3.24e-01 100.0% 17.1%
3534903 4059.1.1.1 a+b complex topology › Serpins › Serpins › Serpins › Serpin 0.60 49.0 2.96e-01 90.0% 47.9%
3168539 109.4.1.69 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › IKI3 0.60 51.0 3.24e-01 100.0% 18.7%
136196 2.1.1.27 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein › RNA_pol_Rpb8 0.60 48.0 3.79e-01 88.3% 79.0%
5028551 2008.1.1.0 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like 0.60 50.0 4.40e-01 96.7% 75.8%
1122053 2003.1.5.81 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_25 0.60 44.0 2.92e-01 80.0% 19.7%
3924310 5.1.4.0 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed 0.59 51.0 3.18e-01 100.0% 22.4%
3618350 5.1.4.14 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › Peptidase_S9_N 0.59 50.0 3.15e-01 100.0% 22.4%
3973387 5.1.5.74 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 8-bladed › DUF3686 0.59 51.0 3.28e-01 100.0% 24.2%
1170462 243.3.1.3 a+b two layers › Cystatin-like › Cystatin/monellin › Cystatin/monellin › PepSY 0.59 48.0 4.85e-01 98.3% 90.2%
4017732 220.1.1.202 beta barrels › PH domain-like › PH domain-like › PH domain-like › PH_FT_N 0.58 50.0 3.78e-01 96.7% 72.7%
3805925 5.1.3.118 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed › FBA_3 0.58 47.0 2.99e-01 100.0% 17.0%
4220972 5.1.3.0 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed 0.58 52.0 3.18e-01 100.0% 19.7%
3918321 4059.1.1.1 a+b complex topology › Serpins › Serpins › Serpins › Serpin 0.58 50.0 3.08e-01 96.7% 41.1%
3843221 4059.1.1.1 a+b complex topology › Serpins › Serpins › Serpins › Serpin 0.58 46.0 2.91e-01 93.3% 42.9%
141145 4059.1.1.0 a+b complex topology › Serpins › Serpins › Serpins 0.58 46.0 2.88e-01 90.0% 49.2%
358183 4059.1.1.0 a+b complex topology › Serpins › Serpins › Serpins 0.58 46.0 2.84e-01 88.3% 50.8%
3487083 4059.1.1.0 a+b complex topology › Serpins › Serpins › Serpins 0.58 47.0 2.91e-01 93.3% 45.6%
3409976 4059.1.1.1 a+b complex topology › Serpins › Serpins › Serpins › Serpin 0.58 46.0 2.84e-01 88.3% 48.9%
3489562 4059.1.1.1 a+b complex topology › Serpins › Serpins › Serpins › Serpin 0.57 46.0 2.84e-01 90.0% 49.4%
4199509 4059.1.1.1 a+b complex topology › Serpins › Serpins › Serpins › Serpin 0.57 49.0 3.04e-01 96.7% 41.1%
2538921 5.1.2.8 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 5-bladed › Glyco_hydro_43 0.57 50.0 3.23e-01 100.0% 28.0%
3862912 4059.1.1.1 a+b complex topology › Serpins › Serpins › Serpins › Serpin 0.57 47.0 2.88e-01 93.3% 43.9%
3411613 5.1.4.0 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed 0.57 50.0 3.09e-01 100.0% 17.1%
3687610 9.2.1.2 beta barrels › Lipocalins/Streptavidin › Avidin/Streptavidin › Avidin/Streptavidin › Vac_ImportDeg 0.57 49.0 3.29e-01 100.0% 78.7%
3594434 10.32.1.0 beta sandwiches › jelly-roll › Galactose-binding domain-like › Galactose-binding domain-like 0.57 49.0 3.45e-01 96.7% 52.6%
3633627 243.1.1.0 a+b two layers › Cystatin-like › NTF2-like › NTF2-like 0.57 48.0 3.74e-01 100.0% 97.2%
4948574 2484.1.1.34 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › DNA_pol_B_exo1 0.56 41.0 2.51e-01 78.3% 38.5%
2389142 4059.1.1.0 a+b complex topology › Serpins › Serpins › Serpins 0.56 48.0 2.99e-01 96.7% 41.5%
4946505 243.3.1.0 a+b two layers › Cystatin-like › Cystatin/monellin › Cystatin/monellin 0.56 48.0 4.65e-01 98.3% 88.6%
3469884 4059.1.1.0 a+b complex topology › Serpins › Serpins › Serpins 0.56 45.0 2.78e-01 90.0% 48.1%
3588678 243.3.1.3 a+b two layers › Cystatin-like › Cystatin/monellin › Cystatin/monellin › PepSY 0.56 47.0 4.61e-01 100.0% 87.7%
5082957 5.1.2.0 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 5-bladed 0.56 46.0 2.98e-01 93.3% 19.6%
3923839 4.1.1.0 beta barrels › SH3 › SH3 › SH3 0.56 38.0 3.69e-01 73.3% 74.3%
3277940 3844.2.1.1 a+b two layers › hydrogenase expression protein-like › MybT EspG5 chaperone › MybT EspG5 chaperone › ESX-1_EspG 0.56 45.0 3.15e-01 98.3% 41.2%
4632151 4059.1.1.1 a+b complex topology › Serpins › Serpins › Serpins › Serpin 0.56 47.0 2.93e-01 96.7% 43.2%
3452696 5.1.3.0 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed 0.56 48.0 3.09e-01 100.0% 25.4%
2803312 4059.1.1.1 a+b complex topology › Serpins › Serpins › Serpins › Serpin 0.55 47.0 2.90e-01 96.7% 43.5%
3442715 5.1.3.144 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed › b-prop_At3g26010-like 0.55 46.0 3.02e-01 100.0% 24.1%
3686359 5.1.4.155 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › MIOS_WD40 0.55 48.0 2.96e-01 100.0% 28.2%
3378208 145.1.1.0 alpha arrays › F-box domain › F-box domain › F-box domain 0.55 41.0 2.77e-01 81.7% 20.2%
3923143 633.23.1.17 alpha bundles › Bromodomain-like › Claudin › Claudin › DuoxA 0.55 44.0 2.97e-01 90.0% 28.7%
3427602 5.1.3.67 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed › FBA_1 0.55 47.0 3.01e-01 100.0% 21.3%
3965259 243.3.1.16 a+b two layers › Cystatin-like › Cystatin/monellin › Cystatin/monellin › PepSY_2 0.55 46.0 4.37e-01 100.0% 79.7%
3930831 5.1.3.0 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed 0.54 44.0 2.97e-01 100.0% 26.4%
3394128 4059.1.1.1 a+b complex topology › Serpins › Serpins › Serpins › Serpin 0.54 46.0 2.87e-01 96.7% 41.9%
3890948 5.1.4.8 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › CNH 0.54 47.0 2.86e-01 100.0% 16.2%
4428983 5.1.4.321 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › PF30361 0.54 47.0 2.80e-01 100.0% 19.4%
3994238 220.1.1.0 beta barrels › PH domain-like › PH domain-like › PH domain-like 0.52 40.0 3.41e-01 83.3% 53.0%
4026437 5.1.3.36 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed › CyRPA 0.52 42.0 2.77e-01 100.0% 23.1%
4890891 108.1.1.0 alpha arrays › EF-hand › EF-hand-related › EF-hand 0.51 42.0 3.34e-01 98.3% 49.3%
3936037 220.1.1.0 beta barrels › PH domain-like › PH domain-like › PH domain-like 0.51 40.0 3.48e-01 83.3% 56.7%
D2 high residues 82-178
PDB
Domain cluster: representative
CATH (28)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
7qh2C03 3.30.70.2740 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.70 48.0 5.25e-01 100.0% 87.2%
4e1oA03 3.90.1150.10 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 0.70 45.0 4.57e-01 100.0% 65.3%
4oj3B00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.70 40.0 4.11e-01 100.0% 57.9%
1yj7B01 3.30.70.1530 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Hypothetical protein rpa1041 0.68 39.0 4.46e-01 100.0% 77.5%
2qmaA02 3.90.1150.10 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 0.68 41.0 3.82e-01 97.9% 47.2%
3hbxA03 3.90.1150.160 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › 0.66 45.0 4.68e-01 100.0% 76.1%
1usmA00 3.30.1360.20 Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › Transcriptional coactivator/pterin dehydratase 0.66 43.0 4.78e-01 100.0% 84.4%
1vk8A00 3.30.70.930 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.66 39.0 3.99e-01 100.0% 61.3%
1svvB02 3.90.1150.10 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 0.65 37.0 3.83e-01 100.0% 57.6%
3m05B01 3.30.70.120 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.65 41.0 4.19e-01 100.0% 66.3%
5tjjB02 3.30.450.40 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › GAF domain 0.61 54.0 4.38e-01 94.8% 95.5%
6t8qA00 3.40.640.10 Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) 0.61 40.0 2.64e-01 100.0% 15.0%
2cveA02 3.30.70.240 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.61 36.0 4.08e-01 99.0% 83.3%
1lxnA00 3.30.70.930 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.61 37.0 3.74e-01 100.0% 60.2%
3bc8A03 3.90.1150.10 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 0.60 49.0 4.42e-01 100.0% 63.0%
5b7sB01 3.90.1150.10 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 0.57 39.0 3.53e-01 100.0% 50.4%
6vh5C03 3.30.70.260 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain 0.57 38.0 3.93e-01 99.0% 73.0%
1r89A02 3.30.460.10 Alpha Beta › 2-Layer Sandwich › Beta Polymerase; domain 2 › Beta Polymerase, domain 2 0.57 47.0 4.28e-01 96.9% 68.0%
4lvnP00 3.30.70.2380 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.56 37.0 3.96e-01 100.0% 79.0%
1b9hA02 3.90.1150.10 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 0.54 47.0 4.17e-01 97.9% 66.2%
1rjjA00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.54 40.0 3.91e-01 100.0% 70.3%
7xhzA01 3.30.1240.10 Alpha Beta › 2-Layer Sandwich › Hypothetical Protein, Haloacid Dehalogenase-like Hydrolase; Chain: A; domain 2 › 0.53 45.0 4.20e-01 94.8% 87.0%
2yqrA01 3.30.1370.10 Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S8; Chain: A, domain 1 › K Homology domain, type 1 0.53 43.0 4.31e-01 100.0% 84.5%
7x4qA01 3.30.460.10 Alpha Beta › 2-Layer Sandwich › Beta Polymerase; domain 2 › Beta Polymerase, domain 2 0.53 44.0 3.81e-01 97.9% 58.3%
3fzqA02 3.30.1240.10 Alpha Beta › 2-Layer Sandwich › Hypothetical Protein, Haloacid Dehalogenase-like Hydrolase; Chain: A; domain 2 › 0.53 47.0 4.42e-01 96.9% 83.5%
5tpvB00 2.60.120.10 Mainly Beta › Sandwich › Jelly Rolls › Jelly Rolls 0.52 33.0 2.99e-01 94.8% 44.2%
3b8xA02 3.90.1150.10 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 0.51 40.0 3.74e-01 95.9% 66.1%
7rsfA01 3.30.70.360 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.50 45.0 4.20e-01 100.0% 82.6%
ECOD (29)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
5038487 304.5.1.0 a+b two layers › Alpha-beta plaits › GlnB-like › GlnB-like 0.71 41.0 4.30e-01 100.0% 61.1%
2092693 316.1.1.21 a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase › Aminoglyc_resit 0.70 47.0 3.79e-01 97.9% 37.3%
4070661 3016.1.1.0 a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases 0.69 44.0 5.17e-01 99.0% 96.9%
3276622 3016.1.1.0 a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases 0.68 48.0 5.40e-01 100.0% 94.7%
3406678 3016.1.1.0 a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases 0.66 45.0 5.01e-01 100.0% 92.0%
5000825 304.24.1.0 a+b two layers › Alpha-beta plaits › EF-G C-terminal domain-like › EF-G C-terminal domain-like 0.64 40.0 4.30e-01 100.0% 72.9%
4990267 316.1.1.39 a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase › DUF2204 0.63 42.0 3.41e-01 95.9% 35.6%
3785807 2008.2.1.1 a/b three-layered sandwiches › Restriction endonuclease-like › tRNA-intron endonuclease catalytic domain-like › tRNA-intron endonuclease catalytic domain-like › tRNA_int_endo 0.61 34.0 3.05e-01 85.6% 36.7%
5014624 316.1.1.2 a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase › NTP_transf_2 0.60 41.0 4.05e-01 91.8% 65.4%
4360849 865.1.1.1 beta complex topology › PheT/TilS domain › PheT/TilS domain › PheT/TilS domain › B3_4 0.59 54.0 4.17e-01 100.0% 80.0%
3269946 304.60.1.0 a+b two layers › Alpha-beta plaits › Ribosomal protein L10-like › Ribosomal protein L10-like 0.58 41.0 3.96e-01 100.0% 64.5%
5030507 3016.1.1.0 a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases 0.57 40.0 4.25e-01 100.0% 83.3%
4999371 241.1.1.0 a+b two layers › Type III secretory system chaperone-like › Type III secretory system chaperone › Type III secretory system chaperone 0.57 50.0 4.31e-01 100.0% 62.0%
4952830 4070.1.1.0 alpha arrays › FtsH protease domain-like › FtsH protease domain-like › FtsH protease domain-like 0.56 40.0 3.24e-01 96.9% 40.0%
3489101 304.60.1.0 a+b two layers › Alpha-beta plaits › Ribosomal protein L10-like › Ribosomal protein L10-like 0.56 43.0 3.57e-01 100.0% 47.9%
3587730 3016.1.1.6 a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › DegT_DnrJ_EryC1 0.55 45.0 4.27e-01 100.0% 74.8%
3631932 221.1.1.0 a+b two layers › beta-Grasp › Ubiquitin-related › Ubiquitin-like 0.54 33.0 3.53e-01 73.2% 69.0%
3743309 327.11.2.0 a+b two layers › Alpha-lytic protease prodomain-like › KH-domains › Eukaryotic type KH-domain (KH-domain type I) 0.54 39.0 4.19e-01 100.0% 90.0%
4956709 304.116.1.0 a+b two layers › Alpha-beta plaits › Ferredoxin-like domain in release factor › Ferredoxin-like domain in release factor 0.54 40.0 4.07e-01 100.0% 80.0%
3181858 304.20.1.0 a+b two layers › Alpha-beta plaits › PAP/Archaeal CCA-adding enzyme, C-terminal domain › PAP/Archaeal CCA-adding enzyme, C-terminal domain 0.54 49.0 4.19e-01 100.0% 67.7%
3609079 223.2.1.0 a+b three layers › Profilin-like › profilin-like › profilin-like 0.54 28.0 2.51e-01 80.4% 31.7%
3983718 304.48.1.14 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › GGDEF 0.53 39.0 3.73e-01 100.0% 67.0%
3723942 327.11.2.59 a+b two layers › Alpha-lytic protease prodomain-like › KH-domains › Eukaryotic type KH-domain (KH-domain type I) › PF29993 0.52 43.0 4.39e-01 100.0% 92.6%
1147602 314.1.1.7 a+b three layers › Class II aaRS and biotin synthetases › Class II aaRS and biotin synthetases › Class II aaRS and biotin synthetases › AsnA 0.51 44.0 3.53e-01 95.9% 66.5%
5040740 4070.1.1.2 alpha arrays › FtsH protease domain-like › FtsH protease domain-like › FtsH protease domain-like › Peptidase_M50 0.51 44.0 3.50e-01 97.9% 57.2%
3229486 327.11.2.0 a+b two layers › Alpha-lytic protease prodomain-like › KH-domains › Eukaryotic type KH-domain (KH-domain type I) 0.51 46.0 4.49e-01 100.0% 93.3%
3685451 304.4.1.0 a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel 0.51 45.0 3.98e-01 100.0% 74.5%
5073773 304.25.1.1 a+b two layers › Alpha-beta plaits › Bacterial exopeptidase dimerisation domain › Bacterial exopeptidase dimerisation domain › M20_dimer 0.50 41.0 3.89e-01 96.9% 74.2%
5033537 4070.1.1.0 alpha arrays › FtsH protease domain-like › FtsH protease domain-like › FtsH protease domain-like 0.50 44.0 3.52e-01 99.0% 58.5%