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IMGVR_UViG_2554235495_000005-2554235495-2556168287
Arc-VirIMGVR_UViG_2554235495_000005-2554235495-2556168287
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
medium
residues 18-138
Domain cluster:
representative
CATH (18)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2dbgA00 | 1.10.533.10 | Mainly Alpha › Orthogonal Bundle › Death Domain, Fas › Death Domain, Fas | 0.60 | 35.0 | 3.73e-01 | 81.0% | 66.0% |
| 1wxpA01 | 1.10.533.10 | Mainly Alpha › Orthogonal Bundle › Death Domain, Fas › Death Domain, Fas | 0.60 | 33.0 | 3.83e-01 | 76.9% | 76.2% |
| 3pubA01 | 1.10.10.2400 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Lepidopteran low molecular weight (30 kD) lipoprotein, N-terminal domain | 0.57 | 31.0 | 3.72e-01 | 76.9% | 82.4% |
| 3juiA00 | 1.25.40.180 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.57 | 46.0 | 4.06e-01 | 86.0% | 60.9% |
| 7e1lB01 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.57 | 46.0 | 3.94e-01 | 87.6% | 81.0% |
| 2vixA03 | 1.20.1280.240 | Mainly Alpha › Up-down Bundle › Monooxygenase › | 0.57 | 40.0 | 4.19e-01 | 86.0% | 79.6% |
| 4mrsA01 | 1.20.1560.10 | Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain | 0.56 | 47.0 | 3.52e-01 | 95.0% | 86.8% |
| 1wa8A00 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.54 | 31.0 | 3.38e-01 | 83.5% | 66.7% |
| 3vvaA00 | 1.20.1260.140 | Mainly Alpha › Up-down Bundle › Ferritin › Alternative oxidase | 0.54 | 46.0 | 3.67e-01 | 95.9% | 79.7% |
| 4iw9A02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.54 | 43.0 | 4.41e-01 | 84.3% | 95.6% |
| 1lkoA01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.52 | 36.0 | 3.42e-01 | 71.1% | 97.9% |
| 5figA00 | 1.20.1270.360 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.52 | 33.0 | 3.54e-01 | 73.6% | 75.0% |
| 1rv2D04 | 1.10.287.690 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › B family DNA polymerase, finger domain | 0.52 | 30.0 | 3.79e-01 | 86.8% | 98.6% |
| 3i5pA01 | 1.25.40.450 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Nucleoporin, helical domain, N-terminal subdomain | 0.51 | 40.0 | 3.94e-01 | 98.3% | 77.9% |
| 4d0nB01 | 1.20.900.10 | Mainly Alpha › Up-down Bundle › Dbl Homology Domain; Chain A › Dbl homology (DH) domain | 0.51 | 42.0 | 3.44e-01 | 92.6% | 69.0% |
| 1ufhA00 | 3.40.630.30 | Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Gcn5-related N-acetyltransferase (GNAT) | 0.51 | 37.0 | 3.40e-01 | 82.6% | 58.7% |
| 2v6yA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.51 | 31.0 | 3.73e-01 | 78.5% | 98.7% |
| 5d91A02 | 1.20.120.1760 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › CDP-alcohol phosphotransferase transmembrane (TM) domain | 0.50 | 40.0 | 3.46e-01 | 86.8% | 85.9% |
ECOD (13)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3668020 | 131.1.1.12 ↗ | alpha complex topology › PDEase-like › HD-domain/PDEase-like › HD-domain/PDEase-like › HD_4 | 0.64 | 49.0 | 4.11e-01 | 86.8% | 47.8% |
| 5001408 | 4995.1.1.0 ↗ | alpha arrays › Methionine synthase domain-like › Methionine synthase domain-like › Methionine synthase domain-like | 0.61 | 44.0 | 4.76e-01 | 78.5% | 90.0% |
| 3580322 | 604.17.1.2 ↗ | alpha bundles › Spectrin repeat-like › MTH_863 C-terminal domain-like › MTH_863 C-terminal domain-like › PF30475 | 0.60 | 37.0 | 4.38e-01 | 80.2% | 97.3% |
| 3647511 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.59 | 32.0 | 2.96e-01 | 90.9% | 40.0% |
| 3920796 | 110.1.1.1 ↗ | alpha arrays › DEATH domain › DEATH domain › DEATH domain › Death | 0.58 | 34.0 | 3.74e-01 | 76.9% | 72.6% |
| 169843 | 110.1.1.1 ↗ | alpha arrays › DEATH domain › DEATH domain › DEATH domain › Death | 0.56 | 35.0 | 3.76e-01 | 81.8% | 74.7% |
| 3311171 | 208.1.1.0 ↗ | beta duplicates or obligate multimers › Single-stranded left-handed beta-helix › Trimeric LpxA-like enzymes › Trimeric LpxA-like enzymes | 0.56 | 40.0 | 3.33e-01 | 73.6% | 87.1% |
| 3881145 | 110.1.1.1 ↗ | alpha arrays › DEATH domain › DEATH domain › DEATH domain › Death | 0.55 | 32.0 | 3.56e-01 | 79.3% | 73.3% |
| 3711125 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.54 | 40.0 | 3.40e-01 | 76.9% | 87.3% |
| 4874447 | 5059.1.1.2 ↗ | alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › Multi_Drug_Res | 0.53 | 40.0 | 4.29e-01 | 79.3% | 100.0% |
| 3557452 | 5069.1.1.4 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › Ferric_reduct | 0.52 | 44.0 | 3.73e-01 | 94.2% | 74.0% |
| 5027224 | 1076.1.1.1 ↗ | alpha bundles › Intramembrane protease Rce1-related › Intramembrane protease Rce1-related › Intramembrane protease Rce1-related › Rce1-like | 0.52 | 43.0 | 3.44e-01 | 90.1% | 85.7% |
| 3442429 | 603.1.1.0 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins | 0.50 | 41.0 | 3.55e-01 | 86.8% | 99.5% |
D2
medium
residues 139-201_477-551
Domain cluster:
representative
CATH (23)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1xioA00 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.65 | 49.0 | 4.22e-01 | 79.0% | 96.3% |
| 1vfpB02 | 1.20.1110.10 | Mainly Alpha › Up-down Bundle › Calcium-transporting ATPase, transmembrane domain › Calcium-transporting ATPase, transmembrane domain | 0.63 | 54.0 | 3.81e-01 | 92.8% | 54.4% |
| 3vkgA02 | 1.20.140.100 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Dynein motor heavy chain, linker domain, N-terminal subdomain | 0.61 | 51.0 | 5.03e-01 | 98.6% | 84.4% |
| 3ajmB02 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.59 | 45.0 | 4.64e-01 | 80.4% | 98.5% |
| 1at9A00 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.58 | 45.0 | 3.80e-01 | 81.2% | 66.1% |
| 3t6gB00 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.58 | 47.0 | 4.76e-01 | 100.0% | 87.3% |
| 1dowA00 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.58 | 43.0 | 3.79e-01 | 100.0% | 52.2% |
| 6xz3A01 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.57 | 44.0 | 4.76e-01 | 98.6% | 96.6% |
| 2yfaA02 | 1.20.1440.210 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › | 0.57 | 42.0 | 4.51e-01 | 100.0% | 90.5% |
| 4w8pA02 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.57 | 44.0 | 4.55e-01 | 100.0% | 86.9% |
| 2l10A00 | 1.20.1420.10 | Mainly Alpha › Up-down Bundle › A middle domain of Talin 1 › Talin, central domain | 0.57 | 43.0 | 4.14e-01 | 100.0% | 69.6% |
| 3q2qA00 | 1.10.600.10 | Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase | 0.56 | 42.0 | 3.30e-01 | 79.0% | 77.7% |
| 1zvzA02 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.56 | 44.0 | 4.62e-01 | 100.0% | 91.1% |
| 1zylA03 | 1.20.1270.170 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.56 | 35.0 | 4.02e-01 | 97.8% | 83.5% |
| 5b2nA00 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.56 | 47.0 | 3.86e-01 | 92.8% | 92.0% |
| 3kv0A01 | 1.10.3520.10 | Mainly Alpha › Orthogonal Bundle › Glycolipid transfer protein, GLTP › Glycolipid transfer protein | 0.56 | 39.0 | 3.63e-01 | 95.7% | 58.2% |
| 2gs4A00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.54 | 43.0 | 4.10e-01 | 83.3% | 86.1% |
| 6ko5A02 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.54 | 43.0 | 3.34e-01 | 84.8% | 96.6% |
| 4xt1A00 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.53 | 42.0 | 3.32e-01 | 83.3% | 91.1% |
| 3ddlA00 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.52 | 47.0 | 3.85e-01 | 100.0% | 73.0% |
| 4dvyP01 | 1.10.357.130 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › | 0.51 | 43.0 | 3.83e-01 | 90.6% | 97.0% |
| 2v0oB00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.51 | 41.0 | 3.24e-01 | 84.1% | 70.5% |
| 2p7vA00 | 1.20.120.1370 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Regulator of RNA polymerase sigma(70) subunit, domain 4 | 0.50 | 44.0 | 4.26e-01 | 100.0% | 86.1% |
ECOD (30)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2388285 | 601.1.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › Vinculin | 0.68 | 47.0 | 4.49e-01 | 100.0% | 60.1% |
| 4982662 | 632.1.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain | 0.67 | 45.0 | 4.54e-01 | 87.0% | 67.9% |
| 3190737 | 5001.1.1.115 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Frag1 | 0.65 | 51.0 | 4.26e-01 | 81.2% | 76.4% |
| 3397834 | 5001.1.1.10 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Ceramidase | 0.63 | 53.0 | 4.20e-01 | 89.1% | 87.2% |
| 3862608 | 601.1.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin | 0.62 | 48.0 | 5.28e-01 | 100.0% | 100.0% |
| 4647869 | 5001.1.1.87 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › EXS | 0.62 | 48.0 | 3.63e-01 | 80.4% | 97.8% |
| 4829492 | 601.18.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Oxygen-evolving enhancer protein 3 › Oxygen-evolving enhancer protein 3 › PsbQ | 0.62 | 43.0 | 4.71e-01 | 98.6% | 88.3% |
| 4001485 | 601.1.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin | 0.61 | 46.0 | 4.62e-01 | 100.0% | 77.9% |
| 3471904 | 601.1.1.57 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › Talin_VBS2 | 0.61 | 45.0 | 4.86e-01 | 100.0% | 91.3% |
| 3509109 | 601.1.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › Vinculin | 0.60 | 45.0 | 4.84e-01 | 98.6% | 92.2% |
| 3253936 | 601.1.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin | 0.60 | 46.0 | 4.72e-01 | 100.0% | 83.0% |
| 3508614 | 601.1.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › Vinculin | 0.59 | 45.0 | 4.45e-01 | 100.0% | 75.2% |
| 3851394 | 601.1.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › Vinculin | 0.59 | 44.0 | 4.59e-01 | 100.0% | 83.1% |
| 3275768 | 601.1.1.7 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › Talin_IBS2B | 0.59 | 44.0 | 4.81e-01 | 98.6% | 94.8% |
| 3474225 | 601.1.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › Vinculin | 0.58 | 45.0 | 4.83e-01 | 100.0% | 94.2% |
| 3234201 | 601.1.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › Vinculin | 0.57 | 43.0 | 4.49e-01 | 100.0% | 86.4% |
| 5042303 | 1203.1.2.19 ↗ | alpha bundles › Shroom domain 2 › Shroom domain 2 › Human SD2 › LPG_synthase_TM | 0.57 | 43.0 | 3.45e-01 | 76.8% | 72.3% |
| 4086368 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.57 | 43.0 | 3.84e-01 | 100.0% | 54.4% |
| 54393 | 601.1.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin | 0.57 | 44.0 | 4.63e-01 | 100.0% | 89.0% |
| 3861849 | 601.1.1.7 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › Talin_IBS2B | 0.57 | 47.0 | 3.52e-01 | 87.0% | 74.5% |
| 2642997 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.56 | 42.0 | 3.77e-01 | 100.0% | 55.7% |
| 3688659 | 5050.1.1.1 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr | 0.56 | 42.0 | 3.34e-01 | 100.0% | 38.9% |
| 3486995 | 601.1.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin | 0.55 | 42.0 | 4.31e-01 | 79.0% | 100.0% |
| 3272925 | 601.1.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin | 0.55 | 43.0 | 4.55e-01 | 100.0% | 91.2% |
| 3570945 | 3567.1.1.82 ↗ | a+b duplicates or obligate multimers › MPER trimer › MPER trimer › MPER trimer › Frag1 | 0.54 | 51.0 | 4.31e-01 | 100.0% | 65.6% |
| 3723619 | 5051.1.1.10 ↗ | alpha complex topology › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › AA_permease_2 | 0.53 | 41.0 | 2.75e-01 | 80.4% | 53.2% |
| 3625640 | 601.1.1.98 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › PF27524 | 0.53 | 43.0 | 4.13e-01 | 97.1% | 76.1% |
| 5046688 | 5001.1.1.0 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like | 0.52 | 41.0 | 3.53e-01 | 84.1% | 68.4% |
| 5014863 | 3755.3.1.524 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › AI-2E_transport | 0.51 | 40.0 | 3.13e-01 | 83.3% | 90.3% |
| 5044955 | 632.22.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats | 0.51 | 43.0 | 4.26e-01 | 97.8% | 86.9% |
D3
medium
residues 202-357
Domain cluster:
representative
CATH (21)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 8fbnB01 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.63 | 45.0 | 3.98e-01 | 100.0% | 51.4% |
| 1vcsA00 | 1.20.58.400 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › t-snare proteins | 0.60 | 36.0 | 4.42e-01 | 78.8% | 92.2% |
| 2jqqA00 | 1.20.58.1240 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.60 | 43.0 | 4.37e-01 | 83.3% | 75.3% |
| 4xriA00 | 1.25.10.10 | Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant | 0.58 | 54.0 | 3.35e-01 | 100.0% | 19.9% |
| 3onjA00 | 1.20.58.400 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › t-snare proteins | 0.58 | 35.0 | 4.40e-01 | 74.4% | 96.9% |
| 1ihgA02 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.57 | 36.0 | 3.71e-01 | 100.0% | 64.8% |
| 5dkoA02 | 1.10.3900.10 | Mainly Alpha › Orthogonal Bundle › YacF-like › YacF-like | 0.56 | 33.0 | 3.28e-01 | 100.0% | 53.3% |
| 2uubT00 | 1.20.58.110 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Ribosomal protein S20 | 0.56 | 33.0 | 3.98e-01 | 82.1% | 89.9% |
| 3l8rA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.56 | 32.0 | 3.90e-01 | 100.0% | 86.3% |
| 4hr1A00 | 1.20.1270.410 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.56 | 28.0 | 3.20e-01 | 94.2% | 61.9% |
| 3n71A03 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.55 | 35.0 | 3.17e-01 | 84.0% | 46.5% |
| 4g10A02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.55 | 37.0 | 3.92e-01 | 79.5% | 77.2% |
| 5jrcA00 | 1.20.58.2140 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.55 | 40.0 | 3.77e-01 | 100.0% | 62.9% |
| 2radA03 | 1.20.1440.30 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › Biosynthetic Protein domain | 0.52 | 33.0 | 3.63e-01 | 98.7% | 77.2% |
| 8a0rA02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.52 | 35.0 | 3.77e-01 | 98.7% | 80.8% |
| 3iv0A00 | 1.25.40.390 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.52 | 47.0 | 3.38e-01 | 100.0% | 65.7% |
| 3e7qA00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.52 | 46.0 | 4.17e-01 | 96.2% | 78.4% |
| 6k6iA00 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.52 | 43.0 | 3.87e-01 | 100.0% | 63.9% |
| 2f3oA00 | 3.20.70.20 | Alpha Beta › Alpha-Beta Barrel › Anaerobic Ribonucleotide-triphosphate Reductase Large Chain › | 0.51 | 44.0 | 2.85e-01 | 94.2% | 96.6% |
| 4qhpA05 | 1.25.50.10 | Mainly Alpha › Alpha Horseshoe › Zincin-like fold › Peptidase M1, alanyl aminopeptidase, C-terminal domain | 0.50 | 44.0 | 3.48e-01 | 96.2% | 71.3% |
| 4gycA00 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.50 | 42.0 | 3.74e-01 | 100.0% | 63.6% |
ECOD (26)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3806870 | 611.3.1.0 ↗ | alpha bundles › N-cbl like › Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 › Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 | 0.67 | 40.0 | 4.95e-01 | 82.7% | 93.0% |
| 3631616 | 109.4.1.509 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › RRP12_HEAT | 0.65 | 54.0 | 4.58e-01 | 98.7% | 55.1% |
| 4998153 | 3352.1.1.0 ↗ | alpha bundles › STT3/PglB/AglB transmembrane domain › STT3/PglB/AglB transmembrane domain › STT3/PglB/AglB transmembrane domain | 0.65 | 53.0 | 3.82e-01 | 85.9% | 51.4% |
| 3182673 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.65 | 43.0 | 3.89e-01 | 100.0% | 48.2% |
| 3765900 | 109.4.1.470 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › INTS2 | 0.63 | 47.0 | 5.17e-01 | 100.0% | 96.8% |
| 3974496 | 3352.1.1.3 ↗ | alpha bundles › STT3/PglB/AglB transmembrane domain › STT3/PglB/AglB transmembrane domain › STT3/PglB/AglB transmembrane domain › PMT | 0.62 | 50.0 | 3.75e-01 | 86.5% | 53.3% |
| 3295175 | 109.4.1.2172 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PF28518 | 0.61 | 48.0 | 3.93e-01 | 100.0% | 43.7% |
| 3786684 | 109.4.1.269 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › EFR3 | 0.60 | 46.0 | 4.34e-01 | 100.0% | 66.8% |
| 4492735 | 4982.1.1.1 ↗ | alpha arrays › KaiA/RbsU domain-like › KaiA/RbsU domain › KaiA/RbsU domain › KaiA | 0.59 | 42.0 | 4.57e-01 | 76.9% | 87.7% |
| 3665501 | 109.4.1.1317 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Vps53_N, VPS53_C | 0.57 | 50.0 | 3.23e-01 | 96.8% | 21.8% |
| 3489166 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.57 | 51.0 | 4.03e-01 | 99.4% | 47.4% |
| 3675605 | 603.1.1.17 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › SNARE | 0.56 | 47.0 | 4.04e-01 | 89.7% | 71.8% |
| 3818564 | 109.4.1.1317 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Vps53_N, VPS53_C | 0.56 | 48.0 | 3.50e-01 | 98.1% | 33.5% |
| 3678902 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.56 | 48.0 | 4.30e-01 | 92.9% | 81.4% |
| 3565139 | 109.4.1.330 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › BIG2_C | 0.55 | 49.0 | 3.43e-01 | 100.0% | 30.7% |
| 3795231 | 109.4.1.330 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › BIG2_C | 0.55 | 45.0 | 3.69e-01 | 100.0% | 48.2% |
| 4240444 | 109.3.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat | 0.55 | 47.0 | 3.44e-01 | 100.0% | 36.4% |
| 3351521 | 603.1.1.98 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › SNARE, Syntaxin_2 | 0.55 | 46.0 | 4.31e-01 | 89.7% | 94.7% |
| 3286286 | 5069.1.1.87 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › PF26314 | 0.55 | 44.0 | 3.31e-01 | 86.5% | 58.3% |
| 3232177 | 109.4.1.1297 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TIMELESS, PF27570 | 0.54 | 48.0 | 3.31e-01 | 97.4% | 45.8% |
| 3882635 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.53 | 36.0 | 4.06e-01 | 100.0% | 88.3% |
| 4034578 | 601.7.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain | 0.53 | 30.0 | 3.29e-01 | 100.0% | 65.4% |
| 3794747 | 109.4.1.1 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › 14-3-3 | 0.52 | 41.0 | 3.36e-01 | 99.4% | 44.3% |
| 3864354 | 109.4.1.330 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › BIG2_C | 0.51 | 47.0 | 3.75e-01 | 100.0% | 80.6% |
| 57900 | 5001.1.1.0 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like | 0.50 | 42.0 | 3.75e-01 | 100.0% | 63.6% |
| 4012748 | 4121.1.1.0 ↗ | a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like | 0.50 | 39.0 | 3.14e-01 | 82.1% | 58.7% |
D4
medium
residues 358-371_399-476
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF04932.21 best | Wzy_C | 43.3 | 4.60e-11 | 79.3% | 45.0% |
CATH (4)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2doeA00 | 1.10.10.440 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › FF domain | 0.58 | 40.0 | 4.20e-01 | 72.8% | 79.5% |
| 3k9vA00 | 1.10.630.10 | Mainly Alpha › Orthogonal Bundle › Cytochrome p450 › Cytochrome P450 | 0.57 | 47.0 | 3.08e-01 | 93.5% | 73.1% |
| 3e1sA01 | 1.10.10.2220 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › | 0.52 | 40.0 | 4.02e-01 | 83.7% | 87.4% |
| 1mukA02 | 3.90.1850.10 | Alpha Beta › Alpha-Beta Complex › RNA-directed RNA polymerase lambda-3 › RNA-directed RNA polymerase lambda-3 | 0.51 | 37.0 | 2.36e-01 | 77.2% | 70.4% |
ECOD (7)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3989196 | 7011.1.1.6 ↗ | alpha bundles › RodA transmembrane domain › RodA transmembrane domain › RodA transmembrane domain › Wzy_C | 0.80 | 59.0 | 3.86e-01 | 100.0% | 19.7% |
| 4301705 | 7011.1.1.6 ↗ | alpha bundles › RodA transmembrane domain › RodA transmembrane domain › RodA transmembrane domain › Wzy_C | 0.77 | 59.0 | 3.66e-01 | 100.0% | 15.7% |
| 4524855 | 7011.1.1.6 ↗ | alpha bundles › RodA transmembrane domain › RodA transmembrane domain › RodA transmembrane domain › Wzy_C | 0.72 | 56.0 | 3.62e-01 | 100.0% | 19.2% |
| 3164267 | 3352.1.1.39 ↗ | alpha bundles › STT3/PglB/AglB transmembrane domain › STT3/PglB/AglB transmembrane domain › STT3/PglB/AglB transmembrane domain › Wzy_C | 0.67 | 62.0 | 4.07e-01 | 98.9% | 30.9% |
| 3687002 | 148.1.1.7 ↗ | alpha arrays › Histone-like › Histone-related › Histone › TAF | 0.63 | 38.0 | 3.55e-01 | 81.5% | 47.0% |
| 5083675 | 7011.1.1.6 ↗ | alpha bundles › RodA transmembrane domain › RodA transmembrane domain › RodA transmembrane domain › Wzy_C | 0.63 | 59.0 | 3.77e-01 | 100.0% | 45.9% |
| 3780971 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.59 | 46.0 | 4.48e-01 | 85.9% | 88.6% |