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IMGVR_UViG_2627853524_000001-2627853524-2627933347

Arc-Vir

IMGVR_UViG_2627853524_000001-2627853524-2627933347

Identity

Kingdom:
archaea

Quality

60.0 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 297-348
PDB
Domain cluster: representative
CATH (35)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2oxlA00 1.20.5.5260 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.75 66.0 6.27e-01 100.0% 91.9%
4dwlA00 1.20.1440.60 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 23S rRNA-intervening sequence 0.75 67.0 5.26e-01 100.0% 81.5%
4dwnA00 1.10.533.10 Mainly Alpha › Orthogonal Bundle › Death Domain, Fas › Death Domain, Fas 0.71 56.0 4.51e-01 84.6% 45.4%
3u3iA02 1.20.58.1110 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.68 56.0 4.43e-01 92.3% 83.3%
3a9fA01 1.10.760.10 Mainly Alpha › Orthogonal Bundle › Cytochrome Bc1 Complex; Chain D, domain 2 › Cytochrome c-like domain 0.68 57.0 5.34e-01 100.0% 94.1%
1svmA01 1.10.10.510 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Zinc finger, large T-antigen D1 domain 0.68 56.0 4.81e-01 98.1% 80.0%
1rvkA01 3.30.390.10 Alpha Beta › 2-Layer Sandwich › Enolase-like; domain 1 › Enolase-like, N-terminal domain 0.67 58.0 4.53e-01 100.0% 90.5%
2gxaE01 1.10.10.510 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Zinc finger, large T-antigen D1 domain 0.67 54.0 4.93e-01 98.1% 67.1%
5mq1A00 1.20.920.10 Mainly Alpha › Up-down Bundle › Histone Acetyltransferase; Chain A › Bromodomain-like 0.66 56.0 4.54e-01 100.0% 76.9%
6s10A01 1.10.1710.10 Mainly Alpha › Orthogonal Bundle › Fertility Inhibition Protein O; Chain: A; Domain 1 › ProQ/FinO domain 0.65 54.0 4.44e-01 98.1% 60.8%
8fnyA01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.64 50.0 3.41e-01 90.4% 22.8%
2w9mA02 1.10.150.20 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › 5' to 3' exonuclease, C-terminal subdomain 0.63 53.0 4.97e-01 100.0% 76.5%
3beeA00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.63 48.0 4.10e-01 86.5% 50.5%
2crbA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.61 50.0 4.10e-01 90.4% 61.9%
2blfB01 1.10.760.10 Mainly Alpha › Orthogonal Bundle › Cytochrome Bc1 Complex; Chain D, domain 2 › Cytochrome c-like domain 0.61 51.0 4.89e-01 100.0% 98.4%
2c5uA02 1.10.3550.20 Mainly Alpha › Orthogonal Bundle › eoxyguanosinetriphosphate triphosphohydrolase fold › 0.61 46.0 3.52e-01 98.1% 33.6%
2ib0A01 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.61 46.0 3.50e-01 82.7% 85.2%
2xevB00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.61 46.0 3.59e-01 84.6% 36.3%
2xzmV01 1.10.60.20 Mainly Alpha › Orthogonal Bundle › Diphtheria Toxin Repressor; domain 2 › Ribosomal protein S17 0.60 50.0 4.83e-01 100.0% 83.6%
1gqeA01 1.20.58.410 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Release factor 0.58 40.0 3.22e-01 73.1% 49.6%
1kt1A03 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.58 44.0 3.14e-01 84.6% 27.2%
6tmfT00 1.10.60.20 Mainly Alpha › Orthogonal Bundle › Diphtheria Toxin Repressor; domain 2 › Ribosomal protein S17 0.58 47.0 4.53e-01 100.0% 79.7%
6qwvH02 1.10.150.50 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Transcription Factor, Ets-1 0.58 49.0 4.79e-01 98.1% 89.7%
2pkeA02 1.10.150.240 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 0.58 49.0 4.38e-01 100.0% 88.5%
3s6jE02 1.10.150.240 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 0.57 49.0 4.48e-01 96.2% 75.4%
4usaA02 1.10.150.120 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › [2Fe-2S]-binding domain 0.57 42.0 3.38e-01 100.0% 37.8%
1b06A01 1.10.287.990 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Fe,Mn superoxide dismutase (SOD) domain 0.56 40.0 3.75e-01 86.5% 61.2%
2g6zA00 3.90.190.10 Alpha Beta › Alpha-Beta Complex › Protein-Tyrosine Phosphatase; Chain A › Protein tyrosine phosphatase superfamily 0.54 45.0 3.36e-01 98.1% 83.7%
4g1tA02 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.53 40.0 3.88e-01 84.6% 75.4%
2lpeA01 6.10.140.1120 Special › Helix non-globular › Helix Hairpins › 0.53 37.0 3.28e-01 96.2% 48.7%
3e3rB01 1.10.238.10 Mainly Alpha › Orthogonal Bundle › Recoverin; domain 1 › EF-hand 0.53 42.0 3.75e-01 100.0% 97.6%
2vxdA00 1.10.10.2100 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Nucleophosmin, C-terminal domain 0.52 44.0 4.40e-01 100.0% 94.4%
2khmA01 1.10.10.1350 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Spidroin domain, C-terminal domain 0.52 41.0 3.42e-01 98.1% 56.5%
2r6aC01 1.10.860.10 Mainly Alpha › Orthogonal Bundle › DNAb Helicase; Chain A › DNAb Helicase; Chain A 0.52 41.0 3.58e-01 100.0% 80.2%
3zhiA00 1.10.260.40 Mainly Alpha › Orthogonal Bundle › 434 Repressor (Amino-terminal Domain) › lambda repressor-like DNA-binding domains 0.51 39.0 3.61e-01 100.0% 64.4%
ECOD (35)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3977558 639.2.1.3 alpha arrays › HHA-like › Regulator of acid resistance influenced by indole (AriR) › Regulator of acid resistance influenced by indole (AriR) › BDM 0.82 73.0 7.23e-01 98.1% 100.0%
3986794 639.2.1.1 alpha arrays › HHA-like › Regulator of acid resistance influenced by indole (AriR) › Regulator of acid resistance influenced by indole (AriR) › YmgB 0.80 72.0 6.49e-01 100.0% 80.0%
4009124 639.2.1.5 alpha arrays › HHA-like › Regulator of acid resistance influenced by indole (AriR) › Regulator of acid resistance influenced by indole (AriR) › PF27475 0.77 68.0 6.54e-01 100.0% 93.3%
3948672 639.2.1.1 alpha arrays › HHA-like › Regulator of acid resistance influenced by indole (AriR) › Regulator of acid resistance influenced by indole (AriR) › YmgB 0.75 65.0 6.38e-01 96.2% 100.0%
5039288 102.1.1.0 alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › SAM domain-like 0.75 67.0 5.70e-01 100.0% 78.6%
4009408 639.2.1.1 alpha arrays › HHA-like › Regulator of acid resistance influenced by indole (AriR) › Regulator of acid resistance influenced by indole (AriR) › YmgB 0.75 65.0 5.97e-01 98.1% 82.4%
4009705 639.2.1.0 alpha arrays › HHA-like › Regulator of acid resistance influenced by indole (AriR) › Regulator of acid resistance influenced by indole (AriR) 0.75 66.0 6.32e-01 100.0% 95.0%
4993604 2006.1.4.50 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › DUF3368 0.74 66.0 4.49e-01 98.1% 30.6%
3943035 639.2.1.0 alpha arrays › HHA-like › Regulator of acid resistance influenced by indole (AriR) › Regulator of acid resistance influenced by indole (AriR) 0.73 62.0 5.85e-01 100.0% 87.7%
3608246 604.12.1.0 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.70 57.0 5.61e-01 88.5% 83.6%
5020822 2007.1.14.25 a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Chelatase-like › PF27317 0.70 56.0 4.32e-01 86.5% 80.9%
5065894 4995.1.1.1 alpha arrays › Methionine synthase domain-like › Methionine synthase domain-like › Methionine synthase domain-like › B12-binding_2 0.70 61.0 5.17e-01 98.1% 76.5%
4953832 7000.1.1.0 alpha arrays › inserted region in the C-terminal domain of the archeal LeuRS › inserted region in the C-terminal domain of the archeal LeuRS › inserted region in the C-terminal domain of the archeal LeuRS 0.69 50.0 4.98e-01 100.0% 74.5%
5045223 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.67 54.0 4.53e-01 100.0% 52.2%
3719014 7525.1.1.1 a/b three-layered sandwiches › Phosphoglycerate mutase-like › Phosphoglycerate mutase-like › Phosphoglycerate mutase-like › His_Phos_1 0.67 60.0 3.54e-01 100.0% 22.9%
4126378 621.1.1.3 alpha bundles › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Sey1_3HB 0.67 54.0 4.24e-01 92.3% 67.0%
3237792 101.35.1.0 alpha arrays › HTH › DNA repair regulatory protein RecX › DNA repair regulatory protein RecX 0.64 53.0 4.75e-01 96.2% 74.7%
4934319 101.1.2.947 alpha arrays › HTH › HTH › winged helix domain › PF27234 0.62 50.0 4.75e-01 100.0% 77.8%
4940562 179.1.1.0 alpha bundles › CO dehydrogenase ISP C-domain like › CO dehydrogenase ISP C-domain like › CO dehydrogenase ISP C-domain like 0.61 47.0 4.55e-01 92.3% 76.7%
3492451 101.35.1.18 alpha arrays › HTH › DNA repair regulatory protein RecX › DNA repair regulatory protein RecX › HSD3 0.60 48.0 4.54e-01 98.1% 74.3%
3931563 101.35.1.0 alpha arrays › HTH › DNA repair regulatory protein RecX › DNA repair regulatory protein RecX 0.60 49.0 4.78e-01 100.0% 88.3%
3494078 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.60 48.0 4.61e-01 98.1% 80.0%
3479514 101.1.2.318 alpha arrays › HTH › HTH › winged helix domain › HSD3 0.60 50.0 4.64e-01 98.1% 80.0%
3702315 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.59 49.0 3.11e-01 98.1% 18.7%
4020688 610.1.1.0 alpha arrays › ERP29 C domain-like › ERP29 C domain-like › ERP29 C domain-like 0.57 46.0 3.88e-01 98.1% 60.0%
3335640 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.56 47.0 4.44e-01 98.1% 86.2%
4952235 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.56 44.0 3.64e-01 88.5% 46.0%
3583094 109.4.1.75 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › IFRD 0.56 42.0 3.11e-01 88.5% 46.7%
3261687 2002.1.1.346 a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › MS_TIM-barrel, MS_C 0.56 47.0 2.75e-01 98.1% 21.5%
5061859 7579.1.1.44 a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases › Abhydrolase_6 0.55 47.0 3.03e-01 98.1% 32.5%
3339435 109.4.1.1257 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR_1, PPR_2 0.55 46.0 3.44e-01 98.1% 55.9%
4322883 601.13.1.11 alpha bundles › Four-helical up-and-down bundle › Flagellar export chaperone FliS › Flagellar export chaperone FliS › FlaF 0.53 39.0 3.33e-01 84.6% 86.0%
3576832 1075.4.1.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › ABC_membrane 0.53 44.0 2.74e-01 98.1% 48.7%
3723093 108.1.1.0 alpha arrays › EF-hand › EF-hand-related › EF-hand 0.52 43.0 3.70e-01 98.1% 73.3%
5022532 101.1.2.0 alpha arrays › HTH › HTH › winged helix domain 0.50 42.0 3.81e-01 98.1% 68.0%
D2 medium residues 7-96_158-188
PDB
D3 medium residues 97-157
PDB
Domain cluster: representative
CATH (53)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2xzmE01 3.30.160.20 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › 0.82 60.0 4.76e-01 100.0% 40.5%
2qkpD00 3.30.450.20 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › PAS domain 0.73 49.0 3.82e-01 83.6% 32.1%
3bf2A00 3.30.160.150 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Lipoprotein like domain 0.72 64.0 5.08e-01 100.0% 59.2%
3caxA02 3.30.450.20 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › PAS domain 0.71 47.0 3.58e-01 83.6% 30.4%
2n8xA00 3.30.160.150 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Lipoprotein like domain 0.70 63.0 4.56e-01 100.0% 49.4%
4jgwA01 1.20.870.10 Mainly Alpha › Up-down Bundle › Son of sevenless (SoS) protein; Chain S, domain 1 › Son of sevenless (SoS) protein Chain: S domain 1 0.70 51.0 3.82e-01 78.7% 43.6%
4ywzB00 3.30.450.20 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › PAS domain 0.69 47.0 3.61e-01 83.6% 30.1%
2rs7A01 3.30.160.20 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › 0.68 51.0 4.81e-01 100.0% 67.6%
1m6kA00 3.40.710.10 Alpha Beta › 3-Layer(aba) Sandwich › Beta-lactamase › DD-peptidase/beta-lactamase superfamily 0.67 52.0 3.51e-01 100.0% 21.6%
1zhhB01 3.30.450.220 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › LuxQ periplasmic domain, N-terminal subdomain 0.66 48.0 3.64e-01 80.3% 34.4%
5bw0F00 3.30.1300.30 Alpha Beta › 2-Layer Sandwich › Pantoate--beta-alanine Ligase; Chain: A,domain 2 › GSPII I/J protein-like 0.66 53.0 4.66e-01 100.0% 59.3%
1tzzB01 3.30.390.10 Alpha Beta › 2-Layer Sandwich › Enolase-like; domain 1 › Enolase-like, N-terminal domain 0.65 58.0 4.68e-01 100.0% 90.8%
2fggA01 3.30.160.240 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Rv1738 0.65 53.0 5.00e-01 100.0% 73.3%
1s5uE00 3.10.129.10 Alpha Beta › Roll › Thiol Ester Dehydrase; Chain A › Hotdog Thioesterase 0.64 48.0 3.70e-01 85.2% 36.0%
2kigA00 2.30.29.110 Mainly Beta › Roll › PH-domain like › 0.64 58.0 4.23e-01 100.0% 82.0%
3hm0A00 3.10.129.10 Alpha Beta › Roll › Thiol Ester Dehydrase; Chain A › Hotdog Thioesterase 0.64 44.0 3.50e-01 85.2% 34.9%
2gj3A00 3.30.450.20 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › PAS domain 0.64 43.0 3.48e-01 70.5% 37.0%
4ffeX00 3.30.500.10 Alpha Beta › 2-Layer Sandwich › Murine Class I Major Histocompatibility Complex, H2-DB; Chain A, domain 1 › MHC class I-like antigen recognition-like 0.64 43.0 3.28e-01 70.5% 65.3%
2v0uA00 3.30.450.20 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › PAS domain 0.63 56.0 4.24e-01 100.0% 42.5%
2gaiA03 2.70.20.10 Mainly Beta › Distorted Sandwich › Topoisomerase I; domain 3 › Topoisomerase I, domain 3 0.62 56.0 4.42e-01 100.0% 54.5%
4ibnA01 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.62 55.0 3.87e-01 100.0% 83.0%
2bi0A01 3.10.129.10 Alpha Beta › Roll › Thiol Ester Dehydrase; Chain A › Hotdog Thioesterase 0.62 45.0 3.36e-01 83.6% 31.4%
3k3dA00 3.30.450.20 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › PAS domain 0.61 40.0 3.24e-01 70.5% 33.3%
4f0jA00 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.60 44.0 2.84e-01 80.3% 61.9%
6m9yA00 3.30.1300.40 Alpha Beta › 2-Layer Sandwich › Pantoate--beta-alanine Ligase; Chain: A,domain 2 › 0.60 39.0 4.02e-01 70.5% 70.2%
3njaA02 2.10.70.100 Mainly Beta › Ribbon › Complement Module; domain 1 › 0.60 41.0 4.67e-01 80.3% 95.7%
4hoiB00 3.30.450.20 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › PAS domain 0.60 42.0 3.50e-01 83.6% 40.4%
4id2A00 2.40.128.510 Mainly Beta › Beta Barrel › Lipocalin › Protein of unknown function DUF4738 0.59 51.0 3.93e-01 100.0% 42.6%
3icyA00 3.30.450.20 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › PAS domain 0.59 40.0 3.20e-01 80.3% 36.4%
2il5A00 3.30.530.20 Alpha Beta › 2-Layer Sandwich › Alpha-D-Glucose-1,6-Bisphosphate; Chain A, domain 4 › START domain 0.59 41.0 3.03e-01 100.0% 27.8%
1rm6A03 3.30.365.10 Alpha Beta › 2-Layer Sandwich › Aldehyde Oxidoreductase; domain 4 › Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain 0.59 41.0 3.20e-01 73.8% 57.6%
6kjuB01 3.30.450.20 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › PAS domain 0.58 40.0 3.26e-01 82.0% 37.6%
1njkA00 3.10.129.10 Alpha Beta › Roll › Thiol Ester Dehydrase; Chain A › Hotdog Thioesterase 0.57 49.0 3.80e-01 96.7% 43.6%
2cduA03 3.30.390.30 Alpha Beta › 2-Layer Sandwich › Enolase-like; domain 1 › FAD/NAD-linked reductase, C-terminal dimerisation domain 0.57 44.0 3.73e-01 88.5% 85.0%
6zxbA02 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.57 48.0 3.74e-01 96.7% 93.8%
3qcpA01 3.40.30.10 Alpha Beta › 3-Layer(aba) Sandwich › Glutaredoxin › Glutaredoxin 0.56 47.0 3.57e-01 100.0% 66.1%
3o2zF00 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.55 41.0 3.89e-01 82.0% 88.3%
4ep4A00 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.54 43.0 3.25e-01 98.4% 33.1%
6yfiB01 3.30.380.10 Alpha Beta › 2-Layer Sandwich › MS2 Viral Coat Protein › MS2 Viral Coat Protein 0.54 46.0 3.64e-01 98.4% 69.6%
2bolA03 2.60.40.790 Mainly Beta › Sandwich › Immunoglobulin-like › 0.54 44.0 3.80e-01 88.5% 62.4%
3volA00 3.30.450.20 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › PAS domain 0.54 35.0 2.77e-01 70.5% 29.0%
3fhwA00 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.53 47.0 4.02e-01 100.0% 78.8%
3en2A00 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.53 45.0 4.04e-01 100.0% 81.3%
2bbhA01 3.30.460.20 Alpha Beta › 2-Layer Sandwich › Beta Polymerase; domain 2 › CorA soluble domain-like 0.52 38.0 2.99e-01 96.7% 33.1%
2dchX02 3.10.28.10 Alpha Beta › Roll › Endonuclease I-creI › Homing endonucleases 0.52 42.0 3.51e-01 90.2% 64.0%
2f96A00 3.30.420.10 Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › Ribonuclease H-like superfamily/Ribonuclease H 0.52 44.0 3.17e-01 100.0% 41.8%
2w4yA00 2.40.160.220 Mainly Beta › Beta Barrel › Porin › 0.52 44.0 3.59e-01 98.4% 60.7%
5aj3Q00 2.40.50.140 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins 0.52 39.0 3.30e-01 83.6% 63.3%
1s3rA02 3.30.1040.20 Alpha Beta › 2-Layer Sandwich › Carboxypeptidase Inhibitor; Chain A › 0.52 35.0 3.79e-01 80.3% 83.0%
3ebyA00 3.10.450.50 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.51 42.0 3.28e-01 98.4% 48.4%
3llcA00 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.51 47.0 3.01e-01 100.0% 98.1%
2y3uA02 3.30.980.50 Alpha Beta › 2-Layer Sandwich › Threonyl-tRNA Synthetase; Chain A, domain 2 › 0.50 37.0 3.14e-01 82.0% 76.1%
4jf8A00 3.10.450.230 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › VirB8 protein 0.50 42.0 3.33e-01 100.0% 47.9%
ECOD (75)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3672943 330.1.1.0 a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like 0.81 64.0 6.28e-01 100.0% 78.5%
3285565 223.1.1.0 a+b three layers › Profilin-like › sensor domains › sensor domains 0.75 52.0 4.30e-01 88.5% 41.9%
3821765 5.1.3.118 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed › FBA_3 0.75 54.0 3.40e-01 100.0% 14.7%
4951932 223.1.1.3 a+b three layers › Profilin-like › sensor domains › sensor domains › GAF 0.73 50.0 3.19e-01 83.6% 14.7%
3703112 223.1.1.0 a+b three layers › Profilin-like › sensor domains › sensor domains 0.72 50.0 3.93e-01 78.7% 36.7%
4978072 512.1.1.0 a+b two layers › a+b domain in putative modulator of DNA gyrase, PmbA/TldD (Pfam 01523) › a+b domain in putative modulator of DNA gyrase, PmbA/TldD (Pfam 01523) › a+b domain in putative modulator of DNA gyrase, PmbA/TldD (Pfam 01523) 0.71 66.0 5.31e-01 100.0% 58.2%
3789933 11.10.1.0 beta sandwiches › Immunoglobulin-like beta-sandwich › TRAF domain-like › TRAF domain-like 0.71 50.0 4.14e-01 73.8% 42.9%
3849982 109.6.1.2 alpha superhelices › Repetitive alpha hairpins › Ras GEF › Ras GEF › RasGEF,RasGEF_N 0.71 53.0 3.14e-01 82.0% 86.3%
3289119 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.70 50.0 3.04e-01 98.4% 11.9%
3481504 330.4.1.1 a+b two layers › dsRBD-like › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobil_deamC 0.70 61.0 4.91e-01 100.0% 64.2%
5046056 223.1.1.13 a+b three layers › Profilin-like › sensor domains › sensor domains › PAS_3 0.69 48.0 3.77e-01 83.6% 33.3%
5062193 244.3.1.3 a+b two layers › FAD-linked reductases, C-terminal domain-like › SufE/NifU › SufE/NifU › CO_deh_flav_C 0.69 51.0 4.12e-01 100.0% 42.7%
3751112 223.2.1.29 a+b three layers › Profilin-like › profilin-like › profilin-like › DENND11 0.69 64.0 4.67e-01 100.0% 40.7%
4931487 223.1.1.14 a+b three layers › Profilin-like › sensor domains › sensor domains › PAS_4 0.69 47.0 3.71e-01 82.0% 34.4%
5034773 223.1.1.25 a+b three layers › Profilin-like › sensor domains › sensor domains › PAS_9 0.68 46.0 3.77e-01 82.0% 39.1%
5019574 223.1.1.2 a+b three layers › Profilin-like › sensor domains › sensor domains › PAS 0.68 48.0 3.89e-01 83.6% 39.1%
3244569 330.1.1.1 a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like › dsrm 0.66 53.0 4.75e-01 100.0% 62.4%
3624927 330.1.1.1 a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like › dsrm 0.66 51.0 4.32e-01 100.0% 49.5%
3588721 223.1.1.2 a+b three layers › Profilin-like › sensor domains › sensor domains › PAS 0.66 47.0 3.83e-01 80.3% 40.0%
3971053 223.1.1.14 a+b three layers › Profilin-like › sensor domains › sensor domains › PAS_4 0.66 46.0 3.82e-01 82.0% 40.9%
4130033 2004.1.1.87 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N 0.65 47.0 2.90e-01 95.1% 12.1%
4962734 223.1.1.14 a+b three layers › Profilin-like › sensor domains › sensor domains › PAS_4 0.65 44.0 3.64e-01 80.3% 39.1%
3510355 216.1.1.4 a+b two layers › UBC-like › UBC-like › UBC-like › RWD 0.65 54.0 4.43e-01 96.7% 80.0%
4951183 223.1.1.14 a+b three layers › Profilin-like › sensor domains › sensor domains › PAS_4 0.65 44.0 3.61e-01 83.6% 37.4%
3410286 216.1.1.0 a+b two layers › UBC-like › UBC-like › UBC-like 0.65 54.0 4.76e-01 96.7% 87.4%
3986460 223.1.1.24 a+b three layers › Profilin-like › sensor domains › sensor domains › PAS_8 0.64 48.0 3.88e-01 82.0% 41.7%
3417120 330.4.1.1 a+b two layers › dsRBD-like › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobil_deamC 0.64 56.0 4.53e-01 100.0% 59.2%
3729142 2008.1.1.0 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like 0.63 51.0 3.42e-01 91.8% 21.1%
5037445 2003.1.5.81 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_25 0.63 49.0 3.18e-01 100.0% 19.6%
4857423 11.1.1.0 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like 0.63 42.0 3.61e-01 72.1% 44.7%
3488617 395.1.1.0 few secondary structure elements › Midkine-related › Midkine-related › Midkine-related 0.63 40.0 4.58e-01 83.6% 88.9%
5083856 223.1.1.2 a+b three layers › Profilin-like › sensor domains › sensor domains › PAS 0.63 44.0 3.59e-01 82.0% 39.1%
5000965 512.1.1.0 a+b two layers › a+b domain in putative modulator of DNA gyrase, PmbA/TldD (Pfam 01523) › a+b domain in putative modulator of DNA gyrase, PmbA/TldD (Pfam 01523) › a+b domain in putative modulator of DNA gyrase, PmbA/TldD (Pfam 01523) 0.63 54.0 4.75e-01 100.0% 64.4%
3711026 7.1.1.16 beta barrels › PDZ domain › PDZ domain › PDZ domain › DUF7762 0.63 49.0 3.98e-01 83.6% 100.0%
3690327 4099.1.1.2 a+b two layers › Kinetochore globular domain-like › Kinetochore globular domain-like › Kinetochore globular domain-like › Spindle_Spc25 0.63 54.0 4.54e-01 100.0% 80.9%
3791028 277.1.1.1 a+b two layers › PX domain › PX domain › PX domain › PX 0.63 53.0 4.33e-01 100.0% 89.6%
3789159 5.1.4.0 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed 0.62 54.0 3.22e-01 100.0% 17.6%
3819047 2484.1.1.67 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RVT_3 0.62 51.0 3.98e-01 100.0% 40.7%
5057039 243.3.1.0 a+b two layers › Cystatin-like › Cystatin/monellin › Cystatin/monellin 0.61 42.0 3.91e-01 72.1% 62.8%
3600849 223.1.1.0 a+b three layers › Profilin-like › sensor domains › sensor domains 0.61 53.0 4.04e-01 100.0% 41.3%
3953766 222.1.1.0 a+b two layers › Thioesterase/thiol ester dehydrase-isomerase-like › Thioesterase/thiol ester dehydrase-isomerase › Thioesterase/thiol ester dehydrase-isomerase 0.61 44.0 3.17e-01 83.6% 25.9%
3289451 243.1.1.63 a+b two layers › Cystatin-like › NTF2-like › NTF2-like › DUF6841 0.61 49.0 3.75e-01 100.0% 38.6%
3836840 2484.1.1.67 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RVT_3 0.60 48.0 3.80e-01 100.0% 40.0%
3824181 375.1.1.21 few secondary structure elements › Rubredoxin-like › Rubredoxin-related › Rubredoxin-related › zf-ZPR1 0.59 48.0 4.92e-01 95.1% 90.0%
4984061 2484.1.1.59 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › NurA 0.59 51.0 3.29e-01 100.0% 21.6%
3959244 223.1.1.13 a+b three layers › Profilin-like › sensor domains › sensor domains › PAS_3 0.59 43.0 3.80e-01 80.3% 52.2%
137752 223.1.1.13 a+b three layers › Profilin-like › sensor domains › sensor domains › PAS_3 0.59 40.0 3.20e-01 80.3% 36.4%
3998954 223.2.1.37 a+b three layers › Profilin-like › profilin-like › profilin-like › C9orf72-like 0.59 52.0 4.08e-01 100.0% 59.2%
5055280 331.4.1.0 a+b two layers › TBP-like › Kinase associated domain 1, KA1 › Kinase associated domain 1, KA1 0.58 49.0 3.68e-01 93.4% 51.0%
4927462 2484.1.1.59 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › NurA 0.58 43.0 2.93e-01 100.0% 19.3%
1491757 719.1.1.3 beta barrels › XRCC4, N-terminal domain-like › XRCC4, N-terminal domain › XRCC4, N-terminal domain › PAXX 0.58 39.0 4.21e-01 95.1% 86.0%
3542721 243.3.1.0 a+b two layers › Cystatin-like › Cystatin/monellin › Cystatin/monellin 0.57 51.0 4.08e-01 100.0% 61.7%
170126 223.1.1.16 a+b three layers › Profilin-like › sensor domains › sensor domains › LuxQ-periplasm 0.57 46.0 3.17e-01 90.2% 46.6%
4950605 223.1.1.14 a+b three layers › Profilin-like › sensor domains › sensor domains › PAS_4 0.57 40.0 3.22e-01 82.0% 36.0%
3724634 243.1.1.63 a+b two layers › Cystatin-like › NTF2-like › NTF2-like › DUF6841 0.57 46.0 3.59e-01 100.0% 40.0%
4551342 223.1.1.0 a+b three layers › Profilin-like › sensor domains › sensor domains 0.56 47.0 4.32e-01 100.0% 74.1%
4973550 223.1.1.0 a+b three layers › Profilin-like › sensor domains › sensor domains 0.56 39.0 3.19e-01 83.6% 37.5%
3425790 243.3.1.19 a+b two layers › Cystatin-like › Cystatin/monellin › Cystatin/monellin › DUF3615 0.56 44.0 3.93e-01 100.0% 57.9%
3612689 2.1.1.0 beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein 0.56 48.0 4.02e-01 98.4% 89.1%
3565382 304.112.1.1 a+b two layers › Alpha-beta plaits › Argonaute, N-terminal domain › Argonaute, N-terminal domain › ArgoL1 0.56 38.0 2.85e-01 73.8% 36.1%
3355925 7579.1.1.0 a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases 0.56 48.0 3.03e-01 98.4% 91.3%
3272235 304.112.1.0 a+b two layers › Alpha-beta plaits › Argonaute, N-terminal domain › Argonaute, N-terminal domain 0.56 38.0 2.97e-01 73.8% 40.6%
4373837 243.1.1.6 a+b two layers › Cystatin-like › NTF2-like › NTF2-like › VirB8 0.55 48.0 3.73e-01 100.0% 48.6%
4008723 223.1.1.2 a+b three layers › Profilin-like › sensor domains › sensor domains › PAS 0.54 37.0 2.97e-01 72.1% 34.6%
5002369 243.1.1.0 a+b two layers › Cystatin-like › NTF2-like › NTF2-like 0.54 46.0 3.76e-01 95.1% 50.4%
4944821 295.1.1.0 a+b two layers › ssDNA-binding transcriptional regulator domain-like › ssDNA-binding transcriptional regulator domain › ssDNA-binding transcriptional regulator domain 0.53 40.0 4.11e-01 91.8% 86.7%
3517350 5.1.5.4 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 8-bladed › DPPIV_N 0.52 41.0 2.63e-01 100.0% 16.6%
4931355 223.1.1.13 a+b three layers › Profilin-like › sensor domains › sensor domains › PAS_3 0.52 38.0 3.21e-01 80.3% 45.5%
3447011 243.3.1.19 a+b two layers › Cystatin-like › Cystatin/monellin › Cystatin/monellin › DUF3615 0.51 41.0 3.18e-01 100.0% 35.8%
3930324 11.10.1.5 beta sandwiches › Immunoglobulin-like beta-sandwich › TRAF domain-like › TRAF domain-like › MATH_2 0.51 42.0 3.43e-01 100.0% 71.9%
4020985 3863.1.1.0 beta barrels › Virulence associated protein B (Vapb) › Virulence associated protein B (Vapb) › Virulence associated protein B (Vapb) 0.51 43.0 3.36e-01 100.0% 70.3%
3925865 214.1.1.1 a+b two layers › SH2 › SH2 › SH2 › SH2 0.51 41.0 3.47e-01 100.0% 60.8%
3600656 206.1.1.0 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase 0.50 41.0 2.59e-01 95.1% 24.5%
4022543 225.1.1.0 a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 0.50 44.0 2.95e-01 98.4% 80.9%
3634542 4099.1.1.0 a+b two layers › Kinetochore globular domain-like › Kinetochore globular domain-like › Kinetochore globular domain-like 0.50 40.0 3.15e-01 100.0% 52.7%