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IMGVR_UViG_2636415715_000001-2636415715-2637701489
Arc-VirIMGVR_UViG_2636415715_000001-2636415715-2637701489
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 9-69_231-284
Domain cluster:
representative
CATH (44)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 7e4gA01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.74 | 48.0 | 3.98e-01 | 83.5% | 38.6% |
| 2crbA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.71 | 42.0 | 4.58e-01 | 95.7% | 70.1% |
| 2wb7A03 | 1.20.120.870 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › pT26-6p, five-helical bundle domain | 0.71 | 47.0 | 4.46e-01 | 78.3% | 57.4% |
| 2z1qB04 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.70 | 47.0 | 4.41e-01 | 77.4% | 57.4% |
| 3rh3A01 | 1.20.120.930 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Uncharacterised protein PF12889, N-terminal DUF3829 | 0.65 | 46.0 | 4.34e-01 | 72.2% | 74.4% |
| 6xz3A01 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.64 | 44.0 | 4.41e-01 | 77.4% | 69.2% |
| 3agtA00 | 1.20.120.50 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hemerythrin-like | 0.63 | 42.0 | 4.00e-01 | 80.9% | 57.9% |
| 6nsjA00 | 1.25.40.600 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › AmiS/UreI transporter | 0.61 | 40.0 | 3.47e-01 | 83.5% | 42.3% |
| 2pkeA02 | 1.10.150.240 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 | 0.61 | 40.0 | 4.59e-01 | 95.7% | 97.4% |
| 4kw3A00 | 3.40.1310.20 | Alpha Beta › 3-Layer(aba) Sandwich › Replication Protein E1; Chain: A, › | 0.59 | 52.0 | 4.01e-01 | 97.4% | 61.7% |
| 3ddhA02 | 1.10.150.240 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 | 0.58 | 39.0 | 4.37e-01 | 95.7% | 95.1% |
| 7eqeB01 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.58 | 37.0 | 3.29e-01 | 86.1% | 43.8% |
| 1yuzB01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.57 | 43.0 | 4.11e-01 | 80.9% | 89.9% |
| 2o57A01 | 1.10.287.840 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Mycolic acid cyclopropane synthase domain like | 0.56 | 42.0 | 4.46e-01 | 93.0% | 85.7% |
| 7aalA01 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.56 | 41.0 | 3.17e-01 | 77.4% | 75.9% |
| 2ntxA01 | 1.20.58.2010 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › PRONE domain, subdomain 1 | 0.55 | 43.0 | 3.54e-01 | 83.5% | 51.4% |
| 2bvlA01 | 1.20.58.1190 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.55 | 40.0 | 4.51e-01 | 94.8% | 100.0% |
| 3f4mA00 | 1.20.1440.160 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › Tumor necrosis factor alpha-induced protein 8-like | 0.54 | 41.0 | 3.68e-01 | 78.3% | 63.6% |
| 1urvA00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.54 | 45.0 | 4.12e-01 | 91.3% | 94.2% |
| 1i5nB00 | 1.20.120.160 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain | 0.54 | 42.0 | 4.12e-01 | 83.5% | 89.5% |
| 3l1nA02 | 1.20.1280.140 | Mainly Alpha › Up-down Bundle › Monooxygenase › | 0.54 | 35.0 | 3.97e-01 | 93.0% | 88.5% |
| 1u89A00 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.53 | 45.0 | 4.17e-01 | 95.7% | 72.7% |
| 1cg5B00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.53 | 42.0 | 3.97e-01 | 85.2% | 90.1% |
| 1oshA00 | 1.10.565.10 | Mainly Alpha › Orthogonal Bundle › Retinoid X Receptor › Retinoid X Receptor | 0.53 | 47.0 | 3.89e-01 | 100.0% | 60.2% |
| 2qf9A01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.53 | 48.0 | 4.30e-01 | 98.3% | 89.1% |
| 4r42A01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.53 | 49.0 | 4.11e-01 | 100.0% | 80.7% |
| 5ojcA00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.53 | 44.0 | 4.03e-01 | 91.3% | 92.2% |
| 1lkoA01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.52 | 48.0 | 4.40e-01 | 97.4% | 84.8% |
| 2chpA00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.52 | 48.0 | 4.39e-01 | 99.1% | 89.2% |
| 2ib0A01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.52 | 48.0 | 4.54e-01 | 100.0% | 86.7% |
| 1oj6A00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.52 | 43.0 | 4.06e-01 | 92.2% | 97.3% |
| 2fzfA01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.52 | 48.0 | 4.39e-01 | 100.0% | 88.7% |
| 2c41C01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.52 | 47.0 | 4.27e-01 | 97.4% | 87.9% |
| 5ux1D00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.52 | 46.0 | 3.90e-01 | 100.0% | 66.5% |
| 1a00B00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.52 | 42.0 | 3.89e-01 | 87.8% | 93.2% |
| 1lvfB00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.52 | 40.0 | 4.24e-01 | 98.3% | 90.4% |
| 3kwoA00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.51 | 46.0 | 4.27e-01 | 100.0% | 87.9% |
| 2vxxA00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.51 | 47.0 | 4.08e-01 | 100.0% | 79.1% |
| 1binA00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.51 | 42.0 | 3.97e-01 | 91.3% | 93.7% |
| 2gs4A00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.51 | 45.0 | 4.13e-01 | 100.0% | 85.4% |
| 3hyuA00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.51 | 41.0 | 3.92e-01 | 89.6% | 90.8% |
| 2cfuA02 | 1.25.40.880 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Alkyl sulfatase, dimerisation domain | 0.50 | 34.0 | 3.16e-01 | 95.7% | 55.3% |
| 2pl2A00 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.50 | 39.0 | 3.27e-01 | 81.7% | 50.0% |
| 2q00B00 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.50 | 37.0 | 3.66e-01 | 77.4% | 76.2% |
ECOD (45)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4978312 | 604.12.1.1 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › MIT | 0.76 | 42.0 | 5.45e-01 | 97.4% | 91.4% |
| 3272556 | 604.12.1.1 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › MIT | 0.76 | 44.0 | 3.60e-01 | 99.1% | 34.4% |
| 3268622 | 604.12.1.1 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › MIT | 0.76 | 44.0 | 4.64e-01 | 99.1% | 63.8% |
| 4972182 | 604.12.1.1 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › MIT | 0.76 | 43.0 | 5.56e-01 | 99.1% | 94.3% |
| 3731082 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.76 | 44.0 | 5.44e-01 | 99.1% | 89.3% |
| 4947260 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.76 | 44.0 | 5.25e-01 | 99.1% | 83.7% |
| 4999686 | 604.12.1.1 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › MIT | 0.75 | 43.0 | 5.30e-01 | 99.1% | 88.0% |
| 4977808 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.75 | 43.0 | 5.56e-01 | 99.1% | 95.7% |
| 4998520 | 604.12.1.1 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › MIT | 0.73 | 41.0 | 5.04e-01 | 97.4% | 85.3% |
| 5072449 | 604.12.1.1 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › MIT | 0.72 | 42.0 | 4.72e-01 | 98.3% | 74.4% |
| 3785380 | 5051.1.1.6 ↗ | alpha complex topology › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › Aa_trans | 0.64 | 58.0 | 3.93e-01 | 100.0% | 95.7% |
| 4879693 | 5054.1.1.0 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels | 0.63 | 40.0 | 3.79e-01 | 80.9% | 53.3% |
| 3586940 | 5051.1.1.2 ↗ | alpha complex topology › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › Sodium:neurotransmitter symporter family (SNF)-like › AA_permease | 0.63 | 56.0 | 3.79e-01 | 100.0% | 89.4% |
| 2543302 | 5054.1.1.58 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › YVC1_C | 0.63 | 40.0 | 3.47e-01 | 80.9% | 42.2% |
| 3579611 | 3883.1.1.1 ↗ | alpha bundles › CDP-alcohol phosphotransferase helical bundle domain › CDP-alcohol phosphotransferase helical bundle domain › CDP-alcohol phosphotransferase helical bundle domain › CDP-OH_P_transf | 0.60 | 48.0 | 3.98e-01 | 84.3% | 75.5% |
| 3290592 | 191.1.1.64 ↗ | alpha bundles › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › DUF4254 | 0.59 | 45.0 | 4.29e-01 | 78.3% | 90.8% |
| 3727013 | 633.21.1.28 ↗ | alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 › SOG2 | 0.57 | 42.0 | 3.62e-01 | 78.3% | 51.9% |
| 3914266 | 150.3.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › 4-helical cytokines › 4-helical cytokine | 0.56 | 48.0 | 4.25e-01 | 93.0% | 65.6% |
| 5014460 | 150.1.1.3 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › Rubrerythrin | 0.55 | 50.0 | 4.43e-01 | 97.4% | 82.4% |
| 3941077 | 106.1.1.0 ↗ | alpha arrays › Globin-like › Globin-like › Globin-like | 0.55 | 46.0 | 4.38e-01 | 93.0% | 95.7% |
| 3911818 | 3832.1.1.1 ↗ | alpha bundles › Tumor necrosis factor alpha-induced protein 8-like protein 2 › Tumor necrosis factor alpha-induced protein 8-like protein 2 › Tumor necrosis factor alpha-induced protein 8-like protein 2 › DUF758 | 0.54 | 41.0 | 3.61e-01 | 78.3% | 61.2% |
| 3914806 | 106.1.1.1 ↗ | alpha arrays › Globin-like › Globin-like › Globin-like › Globin | 0.54 | 44.0 | 4.01e-01 | 87.8% | 90.3% |
| 3645318 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.54 | 43.0 | 3.99e-01 | 82.6% | 72.9% |
| 3306960 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.54 | 43.0 | 3.95e-01 | 82.6% | 70.3% |
| 4871777 | 106.1.1.1 ↗ | alpha arrays › Globin-like › Globin-like › Globin-like › Globin | 0.54 | 44.0 | 4.08e-01 | 89.6% | 94.0% |
| 3663532 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.53 | 42.0 | 3.42e-01 | 82.6% | 50.7% |
| 3284 | 106.1.1.1 ↗ | alpha arrays › Globin-like › Globin-like › Globin-like › Globin | 0.53 | 42.0 | 3.97e-01 | 85.2% | 90.1% |
| 3244338 | 106.1.1.1 ↗ | alpha arrays › Globin-like › Globin-like › Globin-like › Globin | 0.53 | 44.0 | 3.87e-01 | 91.3% | 84.5% |
| 3518542 | 106.1.1.1 ↗ | alpha arrays › Globin-like › Globin-like › Globin-like › Globin | 0.53 | 43.0 | 3.74e-01 | 88.7% | 80.6% |
| 5012225 | 611.6.1.1 ↗ | alpha bundles › N-cbl like › PT26-6P helical domain › PT26-6P helical domain › PT26-6P_helical | 0.53 | 49.0 | 4.51e-01 | 100.0% | 97.2% |
| 3599402 | 102.1.4.0 ↗ | alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › Nop C-terminal domain | 0.53 | 42.0 | 4.04e-01 | 85.2% | 79.2% |
| 3672762 | 109.4.1.191 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_7 | 0.53 | 43.0 | 2.57e-01 | 100.0% | 13.8% |
| 4578863 | 106.1.1.1 ↗ | alpha arrays › Globin-like › Globin-like › Globin-like › Globin | 0.52 | 42.0 | 3.83e-01 | 87.8% | 88.1% |
| 3711833 | 7015.1.1.0 ↗ | alpha bundles › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain | 0.52 | 44.0 | 3.93e-01 | 96.5% | 63.6% |
| 3795477 | 109.1.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › Glutathione S-transferase (GST)-C › Glutathione S-transferase (GST)-C | 0.52 | 47.0 | 4.22e-01 | 100.0% | 87.5% |
| 51101 | 106.1.1.0 ↗ | alpha arrays › Globin-like › Globin-like › Globin-like | 0.52 | 41.0 | 3.92e-01 | 87.8% | 93.7% |
| 3767618 | 7015.1.1.0 ↗ | alpha bundles › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain | 0.52 | 44.0 | 4.33e-01 | 95.7% | 85.6% |
| 3366982 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.52 | 40.0 | 2.62e-01 | 80.0% | 23.5% |
| 4215090 | 131.1.1.12 ↗ | alpha complex topology › PDEase-like › HD-domain/PDEase-like › HD-domain/PDEase-like › HD_4 | 0.51 | 39.0 | 3.21e-01 | 80.0% | 66.3% |
| 4965313 | 150.1.2.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Heme oxygenase/Ribonucleotide reductase | 0.51 | 39.0 | 3.27e-01 | 80.0% | 99.5% |
| 3923390 | 106.1.1.1 ↗ | alpha arrays › Globin-like › Globin-like › Globin-like › Globin | 0.51 | 41.0 | 3.71e-01 | 87.8% | 91.5% |
| 3701591 | 102.1.4.1 ↗ | alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › Nop C-terminal domain › Nop | 0.51 | 41.0 | 3.94e-01 | 86.1% | 78.5% |
| 3601936 | 106.1.1.1 ↗ | alpha arrays › Globin-like › Globin-like › Globin-like › Globin | 0.51 | 41.0 | 3.92e-01 | 89.6% | 93.6% |
| 3354908 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.51 | 40.0 | 3.69e-01 | 98.3% | 65.5% |
| 3288395 | 150.1.1.12 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › DUF4439 | 0.51 | 46.0 | 4.39e-01 | 100.0% | 86.7% |
D2
medium
residues 70-80_144-230
Domain cluster:
rep: IMGVR_UViG_3300011187_000160-3300011187-Ga0136596_100129912__D2-87
D3
medium
residues 81-143