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IMGVR_UViG_2654588017_000001-2654588017-2656630136
Arc-VirIMGVR_UViG_2654588017_000001-2654588017-2656630136
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 35-78_92-125
Domain cluster:
representative
CATH (70)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1d2mA03 | 6.10.140.240 | Special › Helix non-globular › Helix Hairpins › | 0.69 | 49.0 | 5.25e-01 | 73.1% | 87.9% |
| 3h1dA01 | 3.90.1750.10 | Alpha Beta › Alpha-Beta Complex › Hect, E3 ligase catalytic domain fold › Hect, E3 ligase catalytic domains | 0.68 | 46.0 | 3.38e-01 | 94.9% | 28.4% |
| 3a06B03 | 1.10.1740.10 | Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif | 0.67 | 38.0 | 3.70e-01 | 71.8% | 50.0% |
| 3cxbA03 | 1.10.1740.30 | Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › Secreted effector protein SifA helical domain | 0.67 | 44.0 | 4.37e-01 | 85.9% | 65.4% |
| 3iieB03 | 1.10.1740.10 | Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › RNA polymerase sigma factor, region 2, helix turn helix motif | 0.66 | 37.0 | 3.64e-01 | 71.8% | 50.6% |
| 4w8pA02 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.66 | 47.0 | 3.93e-01 | 74.4% | 91.5% |
| 3rlfF04 | 1.10.3720.10 | Mainly Alpha › Orthogonal Bundle › MetI-like fold › MetI-like | 0.66 | 58.0 | 4.15e-01 | 100.0% | 46.2% |
| 2b2hA00 | 1.10.3430.10 | Mainly Alpha › Orthogonal Bundle › Ammonium transporter fold › Ammonium transporter AmtB like domains | 0.64 | 56.0 | 3.56e-01 | 97.4% | 54.2% |
| 3gi7A00 | 1.20.1270.180 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.64 | 46.0 | 4.16e-01 | 74.4% | 75.7% |
| 4ymuD00 | 1.10.3720.10 | Mainly Alpha › Orthogonal Bundle › MetI-like fold › MetI-like | 0.64 | 56.0 | 4.13e-01 | 100.0% | 41.4% |
| 1iurA01 | 1.10.287.110 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › DnaJ domain | 0.63 | 47.0 | 5.11e-01 | 98.7% | 100.0% |
| 3kb9A00 | 1.10.600.10 | Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase | 0.63 | 56.0 | 3.65e-01 | 100.0% | 50.3% |
| 1u89A00 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.63 | 45.0 | 3.75e-01 | 76.9% | 86.3% |
| 7c5wA01 | 3.10.450.50 | Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › | 0.62 | 50.0 | 3.99e-01 | 85.9% | 98.0% |
| 1grlB01 | 1.10.560.10 | Mainly Alpha › Orthogonal Bundle › GROEL; domain 1 › GroEL-like equatorial domain | 0.62 | 53.0 | 3.84e-01 | 100.0% | 78.3% |
| 3h36A00 | 1.10.10.400 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Polyribonucleotide nucleotidyltransferase, RNA-binding domain | 0.62 | 51.0 | 5.17e-01 | 97.4% | 93.6% |
| 4akgA14 | 1.20.1280.160 | Mainly Alpha › Up-down Bundle › Monooxygenase › | 0.61 | 52.0 | 4.72e-01 | 96.2% | 100.0% |
| 1gaxA02 | 1.10.730.10 | Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 | 0.61 | 54.0 | 3.87e-01 | 97.4% | 45.8% |
| 1ileA03 | 1.10.730.10 | Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 | 0.61 | 54.0 | 4.04e-01 | 97.4% | 60.2% |
| 2ra1A03 | 1.20.58.770 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.61 | 44.0 | 4.74e-01 | 93.6% | 93.7% |
| 2gfpA00 | 1.20.1720.10 | Mainly Alpha › Up-down Bundle › Multidrug resistance protein D › Multidrug resistance protein D | 0.61 | 52.0 | 3.42e-01 | 100.0% | 61.6% |
| 1nktA04 | 1.10.3060.10 | Mainly Alpha › Orthogonal Bundle › Helical scaffold and wing domains of SecA › Helical scaffold and wing domains of SecA | 0.60 | 45.0 | 3.47e-01 | 79.5% | 83.1% |
| 3h3mA00 | 1.20.58.380 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Flagellar protein flit. | 0.60 | 54.0 | 5.14e-01 | 100.0% | 85.4% |
| 3oxfA05 | 1.25.40.10 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain | 0.59 | 41.0 | 4.21e-01 | 93.6% | 74.7% |
| 3w0lD02 | 3.40.50.10490 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glucose-6-phosphate isomerase like protein; domain 1 | 0.59 | 51.0 | 3.42e-01 | 100.0% | 77.5% |
| 2ra1A02 | 1.20.58.780 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.59 | 46.0 | 4.87e-01 | 89.7% | 97.1% |
| 3a7mA01 | 1.20.58.380 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Flagellar protein flit. | 0.59 | 52.0 | 4.65e-01 | 100.0% | 69.1% |
| 1rj1A00 | 1.20.140.40 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Invertase/pectin methylesterase inhibitor family protein | 0.59 | 44.0 | 3.57e-01 | 79.5% | 69.6% |
| 2bl2A00 | 1.20.120.610 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › lithium bound rotor ring of v- atpase | 0.58 | 43.0 | 3.37e-01 | 76.9% | 78.2% |
| 5ts9B00 | 1.20.59.10 | Mainly Alpha › Up-down Bundle › Chorismate Mutase Domain, subunit A › Chorismate mutase | 0.58 | 49.0 | 3.91e-01 | 100.0% | 46.0% |
| 1yuzB01 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.58 | 48.0 | 3.97e-01 | 89.7% | 88.4% |
| 1m2vB01 | 1.20.120.730 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Sec23/Sec24 helical domain | 0.58 | 52.0 | 4.04e-01 | 100.0% | 62.7% |
| 2jbwA01 | 1.20.1440.110 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › acylaminoacyl peptidase | 0.58 | 46.0 | 4.17e-01 | 94.9% | 64.1% |
| 1rqgA04 | 1.10.730.10 | Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 | 0.58 | 50.0 | 4.06e-01 | 97.4% | 68.9% |
| 1vcsA00 | 1.20.58.400 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › t-snare proteins | 0.57 | 47.0 | 4.30e-01 | 89.7% | 77.5% |
| 1ug7A00 | 1.20.120.360 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Axin interactor, dorsalization-associated protein, N-terminal domain | 0.57 | 48.0 | 4.07e-01 | 92.3% | 73.4% |
| 2ot4A03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.57 | 44.0 | 3.96e-01 | 83.3% | 67.3% |
| 6cnzF00 | 1.20.59.10 | Mainly Alpha › Up-down Bundle › Chorismate Mutase Domain, subunit A › Chorismate mutase | 0.56 | 49.0 | 3.90e-01 | 100.0% | 48.1% |
| 1wcrA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.56 | 50.0 | 4.61e-01 | 100.0% | 86.4% |
| 7e84A03 | 1.10.287.70 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.56 | 42.0 | 3.60e-01 | 79.5% | 63.4% |
| 2odmA00 | 1.10.287.750 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › SO2669-like | 0.56 | 48.0 | 4.86e-01 | 98.7% | 93.7% |
| 3zc0D00 | 1.20.58.2140 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.56 | 50.0 | 3.79e-01 | 100.0% | 54.5% |
| 1nu7D02 | 1.20.120.760 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Staphylcoagulase, helix bundle, domain 2 | 0.56 | 49.0 | 4.21e-01 | 100.0% | 80.5% |
| 2iiuA00 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.55 | 49.0 | 3.62e-01 | 100.0% | 85.1% |
| 3jz0A02 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.55 | 49.0 | 4.16e-01 | 100.0% | 96.2% |
| 1e2aA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.55 | 50.0 | 4.53e-01 | 100.0% | 87.3% |
| 5d6oA00 | 3.40.50.1820 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain | 0.54 | 41.0 | 2.72e-01 | 83.3% | 70.5% |
| 2pbeA02 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.54 | 49.0 | 4.16e-01 | 100.0% | 94.4% |
| 5gj7A01 | 1.10.540.10 | Mainly Alpha › Orthogonal Bundle › Butyryl-Coa Dehydrogenase, subunit A; domain 1 › Acyl-CoA dehydrogenase/oxidase, N-terminal domain | 0.54 | 46.0 | 3.96e-01 | 94.9% | 59.2% |
| 3pmcA00 | 1.10.490.70 | Mainly Alpha › Orthogonal Bundle › Globin-like › Histidine kinase N-terminal domain | 0.54 | 47.0 | 4.00e-01 | 100.0% | 61.4% |
| 3mvcB00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.54 | 46.0 | 3.77e-01 | 100.0% | 50.0% |
| 3c18A02 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.53 | 46.0 | 3.93e-01 | 92.3% | 79.7% |
| 1ciyA01 | 1.20.190.10 | Mainly Alpha › Up-down Bundle › Delta-Endotoxin; domain 1 › Pesticidal crystal protein, N-terminal domain | 0.53 | 43.0 | 3.15e-01 | 89.7% | 32.1% |
| 8ctsB01 | 1.10.287.70 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.53 | 40.0 | 3.93e-01 | 82.1% | 80.5% |
| 3ousA00 | 1.10.287.70 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.53 | 43.0 | 4.23e-01 | 85.9% | 93.9% |
| 1yxrA01 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.53 | 40.0 | 4.10e-01 | 92.3% | 85.1% |
| 3axjB02 | 1.20.58.200 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 2 | 0.53 | 47.0 | 4.57e-01 | 98.7% | 97.6% |
| 2bnlC00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.53 | 46.0 | 3.92e-01 | 100.0% | 60.4% |
| 1b0bA00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.53 | 45.0 | 3.77e-01 | 98.7% | 98.6% |
| 2jx0A00 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.53 | 46.0 | 3.86e-01 | 96.2% | 77.1% |
| 3b5oA00 | 1.20.910.10 | Mainly Alpha › Up-down Bundle › Heme Oxygenase; Chain A › Heme oxygenase-like | 0.52 | 47.0 | 3.36e-01 | 100.0% | 63.5% |
| 3u8vA00 | 1.20.120.660 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › IL-4 antagonist (De novo design) like domain | 0.52 | 46.0 | 4.55e-01 | 97.4% | 91.6% |
| 1h6gA02 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.52 | 44.0 | 3.77e-01 | 93.6% | 88.7% |
| 3dzaA01 | 1.20.120.1940 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › YfdX protein domain | 0.52 | 45.0 | 3.95e-01 | 97.4% | 81.2% |
| 2jqqA00 | 1.20.58.1240 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.52 | 44.0 | 3.60e-01 | 97.4% | 52.6% |
| 3f7cA00 | 1.20.1590.10 | Mainly Alpha › Up-down Bundle › YP_001051499.1 fold like › YP_001051499.1 domain like | 0.52 | 40.0 | 3.05e-01 | 87.2% | 76.4% |
| 1g2nA00 | 1.10.565.10 | Mainly Alpha › Orthogonal Bundle › Retinoid X Receptor › Retinoid X Receptor | 0.51 | 42.0 | 3.07e-01 | 100.0% | 29.7% |
| 2w31A00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.51 | 44.0 | 3.64e-01 | 100.0% | 90.1% |
| 2hsbA00 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.51 | 43.0 | 3.67e-01 | 92.3% | 88.1% |
| 1gs0A01 | 1.20.142.10 | Mainly Alpha › Up-down Bundle › Poly(ADP-ribose) Polymerase; domain 1 › Poly(ADP-ribose) polymerase, regulatory domain | 0.51 | 43.0 | 3.72e-01 | 96.2% | 72.1% |
ECOD (58)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4954907 | 632.11.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like | 0.73 | 43.0 | 4.22e-01 | 82.1% | 54.1% |
| 3314927 | 7064.1.1.5 ↗ | alpha bundles › Transmembrane domain of VIT1 › Transmembrane domain of VIT1 › Transmembrane domain of VIT1 › ALMT | 0.71 | 65.0 | 5.01e-01 | 100.0% | 47.3% |
| 3782656 | 1075.5.1.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MatE | 0.65 | 58.0 | 4.17e-01 | 100.0% | 75.5% |
| 4449608 | 1075.5.1.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MatE | 0.65 | 57.0 | 4.13e-01 | 100.0% | 44.4% |
| 3889971 | 109.4.1.1643 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › RSLD_CPSF6 | 0.64 | 50.0 | 4.49e-01 | 98.7% | 60.0% |
| 134276 | 3831.1.1.1 ↗ | alpha bundles › Secreted protein of unknown function DUF1311 › Secreted protein of unknown function DUF1311 › Secreted protein of unknown function DUF1311 › LprI | 0.64 | 46.0 | 4.16e-01 | 74.4% | 75.7% |
| 3693277 | 1075.5.1.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MatE | 0.64 | 57.0 | 4.07e-01 | 100.0% | 71.7% |
| 3722567 | 1075.5.1.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MatE | 0.63 | 57.0 | 4.11e-01 | 100.0% | 75.5% |
| 5041648 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.63 | 53.0 | 4.01e-01 | 100.0% | 38.4% |
| 4290271 | 604.9.1.1 ↗ | alpha bundles › Spectrin repeat-like › Ribosomal protein S20 › Ribosomal protein S20 › Ribosomal_S20p | 0.62 | 48.0 | 4.59e-01 | 98.7% | 71.1% |
| 3742790 | 621.1.1.7 ↗ | alpha bundles › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › EMC6 | 0.62 | 55.0 | 5.14e-01 | 100.0% | 86.3% |
| 4964622 | 604.5.1.2 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU | 0.61 | 51.0 | 3.78e-01 | 93.6% | 41.8% |
| 4998387 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.61 | 52.0 | 3.95e-01 | 100.0% | 38.5% |
| 4972771 | 7516.1.1.2 ↗ | a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Glycos_transf_2 | 0.61 | 55.0 | 3.63e-01 | 100.0% | 26.5% |
| 3276574 | 3890.1.1.1 ↗ | alpha bundles › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Transmembrane Bax inhibitor motif (TMBIM) proteins › Bax1-I | 0.61 | 51.0 | 3.80e-01 | 96.2% | 90.4% |
| 4962929 | 1075.5.1.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MatE | 0.60 | 53.0 | 3.87e-01 | 100.0% | 48.9% |
| 3539335 | 3874.1.1.4 ↗ | extended segments › Agnoprotein › Agnoprotein › Agnoprotein › UPF0220 | 0.60 | 44.0 | 3.64e-01 | 78.2% | 99.3% |
| 3727403 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.60 | 52.0 | 3.92e-01 | 100.0% | 40.0% |
| 3214122 | 150.5.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like | 0.59 | 41.0 | 3.50e-01 | 73.1% | 92.6% |
| 3527051 | 604.12.1.0 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain | 0.59 | 47.0 | 4.44e-01 | 94.9% | 70.5% |
| 3971899 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.59 | 49.0 | 3.70e-01 | 100.0% | 36.5% |
| 3846608 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.59 | 47.0 | 3.16e-01 | 89.7% | 56.9% |
| 3204386 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.59 | 53.0 | 4.60e-01 | 100.0% | 97.5% |
| 3992787 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.58 | 49.0 | 3.83e-01 | 100.0% | 42.3% |
| 3944827 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.58 | 50.0 | 3.91e-01 | 98.7% | 82.8% |
| 3388186 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.58 | 50.0 | 3.77e-01 | 100.0% | 37.7% |
| 3652677 | 601.18.1.13 ↗ | alpha bundles › Four-helical up-and-down bundle › Oxygen-evolving enhancer protein 3 › Oxygen-evolving enhancer protein 3 › Vwaint | 0.58 | 52.0 | 4.53e-01 | 100.0% | 67.0% |
| 5048577 | 621.1.1.0 ↗ | alpha bundles › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain | 0.58 | 51.0 | 5.12e-01 | 100.0% | 98.8% |
| 5071516 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.58 | 50.0 | 3.69e-01 | 100.0% | 35.5% |
| 4002913 | 106.1.1.0 ↗ | alpha arrays › Globin-like › Globin-like › Globin-like | 0.57 | 51.0 | 4.01e-01 | 100.0% | 47.3% |
| 4960491 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.57 | 49.0 | 3.67e-01 | 100.0% | 37.0% |
| 3501428 | 106.1.1.0 ↗ | alpha arrays › Globin-like › Globin-like › Globin-like | 0.57 | 50.0 | 4.05e-01 | 100.0% | 51.6% |
| 3938517 | 106.1.1.0 ↗ | alpha arrays › Globin-like › Globin-like › Globin-like | 0.57 | 50.0 | 3.84e-01 | 100.0% | 43.7% |
| 4163021 | 5054.1.1.8 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › Ion_trans_2 | 0.56 | 43.0 | 4.00e-01 | 82.1% | 76.0% |
| 3972311 | 5059.1.1.0 ↗ | alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter | 0.56 | 50.0 | 3.38e-01 | 100.0% | 48.3% |
| 3231223 | 5054.1.1.0 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels | 0.56 | 41.0 | 3.13e-01 | 78.2% | 58.3% |
| 3940998 | 5057.1.1.0 ↗ | alpha bundles › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore › Neurotransmitter-gated ion-channel transmembrane pore | 0.55 | 50.0 | 4.06e-01 | 100.0% | 95.2% |
| 4056054 | 604.10.1.1 ↗ | alpha bundles › Spectrin repeat-like › Enzyme IIa from lactose specific PTS, IIa-lac › Enzyme IIa from lactose specific PTS, IIa-lac › PTS_IIA | 0.55 | 49.0 | 4.42e-01 | 100.0% | 81.8% |
| 3513623 | 106.1.1.1 ↗ | alpha arrays › Globin-like › Globin-like › Globin-like › Globin | 0.55 | 48.0 | 3.84e-01 | 100.0% | 51.5% |
| 3278344 | 1075.1.2.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › MacB transmembrane domain › FtsX | 0.55 | 47.0 | 3.64e-01 | 100.0% | 61.1% |
| 354272 | 5054.1.1.8 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › Ion_trans_2 | 0.54 | 42.0 | 3.89e-01 | 80.8% | 88.5% |
| 4976283 | 5054.1.1.8 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › Ion_trans_2 | 0.54 | 39.0 | 3.46e-01 | 75.6% | 67.0% |
| 5042372 | 5054.1.1.8 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › Ion_trans_2 | 0.54 | 40.0 | 3.64e-01 | 78.2% | 72.1% |
| 3740894 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.54 | 48.0 | 4.59e-01 | 98.7% | 93.3% |
| 4939024 | 604.5.1.2 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU | 0.54 | 47.0 | 3.54e-01 | 98.7% | 41.9% |
| 2846829 | 5054.1.1.8 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › Ion_trans_2 | 0.54 | 40.0 | 3.83e-01 | 79.5% | 84.6% |
| 5013034 | 5054.1.1.8 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › Ion_trans_2 | 0.54 | 38.0 | 3.66e-01 | 74.4% | 84.4% |
| 4959254 | 4953.1.1.41 ↗ | beta barrels › L-aspartase C-terminal domain-like › L-aspartase C-terminal domain-like › L-aspartase C-terminal domain-like › DUF6789 | 0.53 | 46.0 | 3.83e-01 | 100.0% | 76.0% |
| 3459019 | 5054.1.1.0 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels | 0.53 | 39.0 | 3.41e-01 | 76.9% | 72.2% |
| 4976784 | 604.5.1.2 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU | 0.53 | 46.0 | 4.15e-01 | 100.0% | 95.5% |
| 4524416 | 5054.1.1.8 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › Ion_trans_2 | 0.52 | 42.0 | 3.81e-01 | 85.9% | 73.3% |
| 4159391 | 622.1.1.1 ↗ | alpha bundles › YvfG-like › HSC20 (HSCB), C-terminal oligomerisation domain › HSC20 (HSCB), C-terminal oligomerisation domain › HSCB_C | 0.52 | 47.0 | 4.39e-01 | 100.0% | 86.3% |
| 3959665 | 632.1.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain | 0.52 | 42.0 | 3.98e-01 | 88.5% | 80.0% |
| 4995939 | 5054.1.1.8 ↗ | alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › Ion_trans_2 | 0.52 | 38.0 | 3.46e-01 | 78.2% | 73.3% |
| 169963 | 106.1.1.7 ↗ | alpha arrays › Globin-like › Globin-like › Globin-like › Protoglobin | 0.51 | 44.0 | 3.64e-01 | 100.0% | 90.1% |
| 3953975 | 632.1.1.3 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain › Alpha-mann_mid | 0.51 | 41.0 | 3.90e-01 | 88.5% | 80.0% |
| 3409714 | 604.3.1.1 ↗ | alpha bundles › Spectrin repeat-like › BAG domain › BAG domain › BAG | 0.51 | 44.0 | 4.15e-01 | 98.7% | 79.0% |
| 3482907 | 3291.1.1.0 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related | 0.51 | 46.0 | 4.05e-01 | 100.0% | 87.8% |