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IMGVR_UViG_2654588138_000002-2654588138-2657039776
Arc-VirIMGVR_UViG_2654588138_000002-2654588138-2657039776
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 5-110
Domain cluster:
rep: SR-VP_0-2_scaffold_141_4750547_curated_closed_complete_prodigal-single.1__X__X__00649__D23-135
CATH (44)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3he1A00 | 2.30.110.20 | Mainly Beta › Roll › Pnp Oxidase; Chain A › Hcp1-like | 0.81 | 67.0 | 5.90e-01 | 86.8% | 90.5% |
| 4w64B00 | 2.30.110.20 | Mainly Beta › Roll › Pnp Oxidase; Chain A › Hcp1-like | 0.81 | 67.0 | 5.71e-01 | 86.8% | 84.4% |
| 1y12B00 | 2.30.110.20 | Mainly Beta › Roll › Pnp Oxidase; Chain A › Hcp1-like | 0.80 | 66.0 | 5.72e-01 | 86.8% | 82.7% |
| 4hkhA00 | 2.30.110.20 | Mainly Beta › Roll › Pnp Oxidase; Chain A › Hcp1-like | 0.80 | 66.0 | 5.81e-01 | 86.8% | 91.3% |
| 2x8kA01 | 2.40.30.200 | Mainly Beta › Beta Barrel › Elongation Factor Tu (Ef-tu); domain 3 › | 0.74 | 59.0 | 6.00e-01 | 84.9% | 98.1% |
| 4feuF01 | 3.30.200.20 | Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 | 0.71 | 45.0 | 5.31e-01 | 84.0% | 91.8% |
| 3pftA00 | 2.30.110.10 | Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A | 0.71 | 58.0 | 5.09e-01 | 87.7% | 81.4% |
| 8ct0B01 | 2.30.110.10 | Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A | 0.70 | 57.0 | 4.91e-01 | 87.7% | 78.9% |
| 3d37B01 | 2.30.300.10 | Mainly Beta › Roll › Phage tail proteins - horseshoe like beta roll fold › Baseplate protein-like domain - beta roll fold | 0.69 | 50.0 | 4.22e-01 | 80.2% | 46.0% |
| 3fgeA01 | 2.30.110.10 | Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A | 0.69 | 56.0 | 4.79e-01 | 87.7% | 86.6% |
| 1wruA01 | 2.30.300.10 | Mainly Beta › Roll › Phage tail proteins - horseshoe like beta roll fold › Baseplate protein-like domain - beta roll fold | 0.69 | 55.0 | 4.62e-01 | 84.9% | 72.0% |
| 3kyfA02 | 2.40.10.220 | Mainly Beta › Beta Barrel › Thrombin, subunit H › predicted glycosyltransferase like domains | 0.68 | 59.0 | 5.70e-01 | 92.5% | 88.9% |
| 5ih0A01 | 3.30.200.20 | Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 | 0.67 | 44.0 | 4.74e-01 | 84.9% | 77.4% |
| 2q9kA00 | 2.30.110.10 | Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A | 0.66 | 58.0 | 5.18e-01 | 95.3% | 77.6% |
| 5xd6B01 | 3.30.200.20 | Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 | 0.65 | 44.0 | 4.62e-01 | 84.9% | 76.6% |
| 3uimA01 | 3.30.200.20 | Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 | 0.65 | 42.0 | 4.53e-01 | 84.0% | 77.5% |
| 1wv4B00 | 2.30.110.10 | Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A | 0.63 | 55.0 | 4.94e-01 | 99.1% | 77.9% |
| 1t9mA00 | 2.30.110.10 | Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A | 0.62 | 55.0 | 4.51e-01 | 100.0% | 83.3% |
| 4pdyA01 | 3.30.200.20 | Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 | 0.61 | 42.0 | 4.39e-01 | 86.8% | 75.8% |
| 2v4jB01 | 3.30.70.3340 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.61 | 39.0 | 3.62e-01 | 87.7% | 51.5% |
| 3ke6A02 | 3.30.565.10 | Alpha Beta › 2-Layer Sandwich › Heat Shock Protein 90 › Histidine kinase-like ATPase, C-terminal domain | 0.59 | 50.0 | 4.75e-01 | 91.5% | 91.3% |
| 2bolB02 | 2.60.40.790 | Mainly Beta › Sandwich › Immunoglobulin-like › | 0.59 | 46.0 | 4.37e-01 | 83.0% | 98.4% |
| 4i93A01 | 3.30.200.20 | Alpha Beta › 2-Layer Sandwich › Phosphorylase Kinase; domain 1 › Phosphorylase Kinase; domain 1 | 0.59 | 41.0 | 4.33e-01 | 84.9% | 80.0% |
| 2q7aA00 | 2.60.40.1850 | Mainly Beta › Sandwich › Immunoglobulin-like › | 0.59 | 50.0 | 4.45e-01 | 92.5% | 88.2% |
| 2wcrB00 | 3.10.129.140 | Alpha Beta › Roll › Thiol Ester Dehydrase; Chain A › Helicobacter TNF-alpha-Inducing protein | 0.59 | 41.0 | 3.67e-01 | 71.7% | 78.1% |
| 4ic6C01 | 2.40.10.10 | Mainly Beta › Beta Barrel › Thrombin, subunit H › Trypsin-like serine proteases | 0.58 | 46.0 | 4.56e-01 | 89.6% | 82.7% |
| 4hudA01 | 3.30.2000.40 | Alpha Beta › 2-Layer Sandwich › STM4215-like › Myoviridae tail sheath stabiliser | 0.56 | 50.0 | 4.07e-01 | 100.0% | 95.7% |
| 1h3gA01 | 2.60.40.10 | Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins | 0.56 | 41.0 | 4.41e-01 | 77.4% | 97.8% |
| 1wnhA02 | 3.10.450.10 | Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › | 0.55 | 42.0 | 4.06e-01 | 80.2% | 89.2% |
| 4gf3A00 | 3.30.1460.10 | Alpha Beta › 2-Layer Sandwich › Yope Regulator; Chain: A, › | 0.55 | 48.0 | 4.57e-01 | 95.3% | 95.9% |
| 1j6wA00 | 3.30.1360.80 | Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › S-ribosylhomocysteinase (LuxS) | 0.55 | 43.0 | 3.72e-01 | 84.0% | 54.0% |
| 3ayhB01 | 3.30.1490.120 | Alpha Beta › 2-Layer Sandwich › Dna Ligase; domain 1 › RNA polymerase Rpb7-like, N-terminal domain | 0.54 | 37.0 | 4.08e-01 | 93.4% | 93.7% |
| 3h2bB00 | 3.40.50.150 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 | 0.53 | 44.0 | 3.59e-01 | 88.7% | 79.1% |
| 2fsdA00 | 2.60.40.2460 | Mainly Beta › Sandwich › Immunoglobulin-like › Phage bIL170 RBP, head domain | 0.52 | 43.0 | 4.26e-01 | 91.5% | 100.0% |
| 3rgaA02 | 3.10.450.50 | Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › | 0.51 | 39.0 | 3.60e-01 | 84.0% | 100.0% |
| 2pn5A10 | 2.60.40.690 | Mainly Beta › Sandwich › Immunoglobulin-like › Alpha-macroglobulin, receptor-binding domain | 0.51 | 41.0 | 3.66e-01 | 84.9% | 72.6% |
| 3wa5B00 | 2.60.120.1690 | Mainly Beta › Sandwich › Jelly Rolls › | 0.51 | 38.0 | 3.68e-01 | 86.8% | 68.5% |
| 2yh9B00 | 3.30.1450.10 | Alpha Beta › 2-Layer Sandwich › Beta-lactamase Inhibitory Protein; Chain:B, domain 1 › | 0.51 | 25.0 | 3.00e-01 | 89.6% | 67.6% |
| 3eo6A00 | 2.60.120.10 | Mainly Beta › Sandwich › Jelly Rolls › Jelly Rolls | 0.51 | 41.0 | 4.12e-01 | 85.8% | 90.6% |
| 3glaA00 | 2.60.40.790 | Mainly Beta › Sandwich › Immunoglobulin-like › | 0.51 | 38.0 | 3.94e-01 | 78.3% | 99.0% |
| 1qwdB00 | 2.40.128.20 | Mainly Beta › Beta Barrel › Lipocalin › Calycin beta-barrel core domain | 0.51 | 46.0 | 3.96e-01 | 99.1% | 65.7% |
| 3bgaA05 | 2.70.98.10 | Mainly Beta › Distorted Sandwich › Beta-galactosidase; Chain A, domain 5 › | 0.51 | 45.0 | 3.36e-01 | 99.1% | 99.6% |
| 4dsdA00 | 3.40.1420.30 | Alpha Beta › 3-Layer(aba) Sandwich › Inhibitor of vertebrate lysozyme, Ivy › | 0.50 | 40.0 | 3.77e-01 | 82.1% | 78.6% |
| 3hqxA00 | 2.60.120.10 | Mainly Beta › Sandwich › Jelly Rolls › Jelly Rolls | 0.50 | 40.0 | 4.09e-01 | 86.8% | 94.3% |
ECOD (74)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4952909 | 1.1.5.0 ↗ | beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel | 0.98 | 90.0 | 9.12e-01 | 94.3% | 95.2% |
| 4878666 | 1.1.5.23 ↗ | beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › T6SS_HCP | 0.85 | 70.0 | 6.34e-01 | 86.8% | 90.6% |
| 5078836 | 1.1.13.0 ↗ | beta barrels › cradle loop barrel › RIFT-related › Phage tail proteins | 0.83 | 68.0 | 6.74e-01 | 85.8% | 100.0% |
| 4954551 | 1.1.5.0 ↗ | beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel | 0.82 | 68.0 | 6.17e-01 | 86.8% | 91.9% |
| 4982153 | 1.1.5.0 ↗ | beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel | 0.81 | 67.0 | 4.85e-01 | 86.8% | 50.0% |
| 4988100 | 1.1.13.0 ↗ | beta barrels › cradle loop barrel › RIFT-related › Phage tail proteins | 0.80 | 65.0 | 6.15e-01 | 84.9% | 100.0% |
| 3977123 | 1.1.5.23 ↗ | beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › T6SS_HCP | 0.80 | 67.0 | 5.73e-01 | 87.7% | 84.4% |
| 5081561 | 1.1.13.0 ↗ | beta barrels › cradle loop barrel › RIFT-related › Phage tail proteins | 0.80 | 58.0 | 6.62e-01 | 79.2% | 100.0% |
| 4514734 | 1.1.13.42 ↗ | beta barrels › cradle loop barrel › RIFT-related › Phage tail proteins › Tail_tube | 0.79 | 64.0 | 6.31e-01 | 84.9% | 100.0% |
| 184986 | 1.1.13.4 ↗ | beta barrels › cradle loop barrel › RIFT-related › Phage tail proteins › Sipho_tail | 0.76 | 59.0 | 5.62e-01 | 82.1% | 99.2% |
| 4959581 | 1.1.5.0 ↗ | beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel | 0.76 | 64.0 | 5.18e-01 | 92.5% | 50.0% |
| 4988103 | 1.1.13.0 ↗ | beta barrels › cradle loop barrel › RIFT-related › Phage tail proteins | 0.74 | 56.0 | 5.89e-01 | 79.2% | 98.9% |
| 4393593 | 1.1.13.5 ↗ | beta barrels › cradle loop barrel › RIFT-related › Phage tail proteins › Phage_GPD | 0.72 | 56.0 | 5.85e-01 | 81.1% | 98.9% |
| 3967435 | 1.1.13.5 ↗ | beta barrels › cradle loop barrel › RIFT-related › Phage tail proteins › Phage_GPD | 0.72 | 54.0 | 5.71e-01 | 79.2% | 95.8% |
| 184471 | 1.1.13.26 ↗ | beta barrels › cradle loop barrel › RIFT-related › Phage tail proteins › GpP-like_1st | 0.72 | 54.0 | 5.91e-01 | 78.3% | 100.0% |
| 3966280 | 1.1.13.0 ↗ | beta barrels › cradle loop barrel › RIFT-related › Phage tail proteins | 0.72 | 54.0 | 5.67e-01 | 79.2% | 95.8% |
| 3972305 | 1.1.13.0 ↗ | beta barrels › cradle loop barrel › RIFT-related › Phage tail proteins | 0.72 | 54.0 | 5.76e-01 | 78.3% | 100.0% |
| 5041372 | 1.1.13.0 ↗ | beta barrels › cradle loop barrel › RIFT-related › Phage tail proteins | 0.70 | 54.0 | 5.79e-01 | 80.2% | 97.8% |
| 4379249 | 1.1.5.25 ↗ | beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › PilZ | 0.70 | 60.0 | 5.70e-01 | 93.4% | 88.0% |
| 169881 | 1.1.5.10 ↗ | beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel › Flavin_Reduct | 0.69 | 56.0 | 4.58e-01 | 87.7% | 75.3% |
| 4031285 | 1.1.13.64 ↗ | beta barrels › cradle loop barrel › RIFT-related › Phage tail proteins › TT1_Tal | 0.69 | 52.0 | 5.57e-01 | 79.2% | 100.0% |
| 3968713 | 1.1.13.5 ↗ | beta barrels › cradle loop barrel › RIFT-related › Phage tail proteins › Phage_GPD | 0.68 | 52.0 | 5.59e-01 | 81.1% | 97.8% |
| 4371717 | 206.1.1.11 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › APH | 0.67 | 50.0 | 3.73e-01 | 91.5% | 31.4% |
| 4889788 | 1.1.13.0 ↗ | beta barrels › cradle loop barrel › RIFT-related › Phage tail proteins | 0.67 | 51.0 | 5.30e-01 | 80.2% | 100.0% |
| 3329275 | 206.1.1.20 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › PK_Tyr_Ser-Thr | 0.67 | 50.0 | 3.57e-01 | 90.6% | 27.7% |
| 4883825 | 1.1.13.20 ↗ | beta barrels › cradle loop barrel › RIFT-related › Phage tail proteins › Prophage_tailD1 | 0.67 | 50.0 | 5.40e-01 | 79.2% | 98.9% |
| 164720 | 1.1.5.0 ↗ | beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel | 0.66 | 58.0 | 5.18e-01 | 95.3% | 77.6% |
| 3312396 | 206.1.1.20 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › PK_Tyr_Ser-Thr | 0.66 | 50.0 | 3.54e-01 | 91.5% | 26.5% |
| 3966522 | 225.1.1.11 ↗ | a+b two layers › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase › DUF6272 | 0.66 | 53.0 | 4.48e-01 | 86.8% | 93.7% |
| 3804680 | 206.1.1.1 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase | 0.65 | 49.0 | 3.40e-01 | 91.5% | 23.9% |
| 4960006 | 1.1.5.0 ↗ | beta barrels › cradle loop barrel › RIFT-related › FMN-binding split barrel | 0.65 | 56.0 | 5.64e-01 | 96.2% | 100.0% |
| 3678082 | 206.1.1.20 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › PK_Tyr_Ser-Thr | 0.65 | 48.0 | 2.79e-01 | 90.6% | 8.6% |
| 3833385 | 206.1.1.20 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › PK_Tyr_Ser-Thr | 0.64 | 47.0 | 4.16e-01 | 91.5% | 54.0% |
| 3679265 | 206.1.1.0 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase | 0.64 | 48.0 | 3.93e-01 | 90.6% | 43.1% |
| 3314292 | 206.1.1.20 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › PK_Tyr_Ser-Thr | 0.64 | 47.0 | 3.35e-01 | 91.5% | 25.5% |
| 3317603 | 206.1.1.20 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › PK_Tyr_Ser-Thr | 0.63 | 48.0 | 3.46e-01 | 91.5% | 28.1% |
| 3672488 | 206.1.1.20 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › PK_Tyr_Ser-Thr | 0.63 | 49.0 | 3.38e-01 | 91.5% | 24.5% |
| 3645097 | 206.1.1.20 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › PK_Tyr_Ser-Thr | 0.63 | 48.0 | 3.36e-01 | 90.6% | 25.8% |
| 3593335 | 206.1.1.0 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase | 0.62 | 45.0 | 3.31e-01 | 91.5% | 28.6% |
| 3457708 | 206.1.1.20 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › PK_Tyr_Ser-Thr | 0.61 | 46.0 | 3.71e-01 | 91.5% | 40.5% |
| 3177693 | 206.1.1.1 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase | 0.61 | 47.0 | 3.20e-01 | 91.5% | 22.9% |
| 4978012 | 206.1.1.0 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase | 0.61 | 51.0 | 3.55e-01 | 91.5% | 28.4% |
| 3322500 | 206.1.1.20 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › PK_Tyr_Ser-Thr | 0.61 | 50.0 | 3.50e-01 | 91.5% | 28.1% |
| 3476907 | 206.1.1.1 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase | 0.60 | 49.0 | 3.47e-01 | 91.5% | 29.1% |
| 3837073 | 206.1.1.20 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › PK_Tyr_Ser-Thr | 0.60 | 48.0 | 3.48e-01 | 91.5% | 30.7% |
| 3674718 | 206.1.1.1 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase | 0.60 | 50.0 | 3.42e-01 | 90.6% | 27.6% |
| 3209472 | 206.1.1.11 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › APH | 0.60 | 49.0 | 3.45e-01 | 92.5% | 28.6% |
| 3652231 | 206.1.1.20 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › PK_Tyr_Ser-Thr | 0.60 | 50.0 | 3.64e-01 | 90.6% | 40.5% |
| 3432155 | 206.1.1.20 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › PK_Tyr_Ser-Thr | 0.59 | 49.0 | 4.07e-01 | 91.5% | 51.4% |
| 3677503 | 206.1.1.1 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase | 0.59 | 47.0 | 3.26e-01 | 91.5% | 26.1% |
| 3310878 | 206.1.1.20 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › PK_Tyr_Ser-Thr | 0.59 | 48.0 | 2.97e-01 | 90.6% | 15.7% |
| 3818900 | 206.1.1.72 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase, Pkinase_fungal | 0.59 | 48.0 | 3.41e-01 | 91.5% | 30.0% |
| 3223139 | 206.1.1.0 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase | 0.59 | 45.0 | 3.18e-01 | 90.6% | 26.5% |
| 4513450 | 319.1.1.0 ↗ | beta sandwiches › HSP20-like › HSP20-like chaperones › HSP20-like chaperones | 0.59 | 43.0 | 4.40e-01 | 77.4% | 97.1% |
| 3351405 | 206.1.1.1 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase | 0.58 | 48.0 | 3.31e-01 | 91.5% | 26.6% |
| 3950370 | 881.4.1.3 ↗ | a+b three layers › Mog1p/PsbP-like › C-terminal domain in sigma-E factor regulatory protein rseB › C-terminal domain in sigma-E factor regulatory protein rseB › DUF4245 | 0.58 | 48.0 | 4.18e-01 | 86.8% | 72.9% |
| 4987232 | 304.102.1.2 ↗ | a+b two layers › Alpha-beta plaits › Pseudouridine synthase › Pseudouridine synthase › TruD | 0.58 | 45.0 | 3.75e-01 | 82.1% | 94.1% |
| 3439329 | 206.1.1.1 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase | 0.58 | 46.0 | 3.18e-01 | 91.5% | 24.6% |
| 3655500 | 206.1.1.1 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase | 0.58 | 49.0 | 3.46e-01 | 91.5% | 32.0% |
| 3333877 | 206.1.1.1 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase | 0.58 | 47.0 | 3.25e-01 | 91.5% | 25.9% |
| 5010092 | 881.1.1.0 ↗ | a+b three layers › Mog1p/PsbP-like › Mog1p/PsbP-like › Mog1p/PsbP-like | 0.57 | 43.0 | 4.25e-01 | 86.8% | 73.0% |
| 3452245 | 206.1.1.1 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase | 0.57 | 48.0 | 3.31e-01 | 90.6% | 28.0% |
| 3628091 | 206.1.1.1 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase | 0.57 | 49.0 | 2.97e-01 | 92.5% | 14.7% |
| 3832784 | 206.1.1.1 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase | 0.57 | 48.0 | 3.32e-01 | 91.5% | 28.1% |
| 3289852 | 881.1.1.0 ↗ | a+b three layers › Mog1p/PsbP-like › Mog1p/PsbP-like › Mog1p/PsbP-like | 0.57 | 46.0 | 3.81e-01 | 88.7% | 77.2% |
| 3668463 | 331.3.1.0 ↗ | a+b two layers › TBP-like › Bet v1-like › Bet v1-like | 0.57 | 47.0 | 3.60e-01 | 89.6% | 75.4% |
| 4952518 | 881.1.1.0 ↗ | a+b three layers › Mog1p/PsbP-like › Mog1p/PsbP-like › Mog1p/PsbP-like | 0.57 | 43.0 | 4.28e-01 | 87.7% | 77.3% |
| 3281552 | 881.4.1.3 ↗ | a+b three layers › Mog1p/PsbP-like › C-terminal domain in sigma-E factor regulatory protein rseB › C-terminal domain in sigma-E factor regulatory protein rseB › DUF4245 | 0.56 | 45.0 | 4.19e-01 | 86.8% | 67.4% |
| 3462996 | 206.1.1.20 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › PK_Tyr_Ser-Thr | 0.56 | 47.0 | 3.28e-01 | 91.5% | 27.7% |
| 3438188 | 206.1.1.1 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase | 0.55 | 46.0 | 3.25e-01 | 91.5% | 34.5% |
| 3672513 | 206.1.1.74 ↗ | a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase, PK_Tyr_Ser-Thr | 0.55 | 45.0 | 3.12e-01 | 90.6% | 25.9% |
| 5068348 | 11.12.1.0 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Nicotinic receptor ligand binding domain-like › Nicotinic receptor ligand binding domain-like | 0.53 | 43.0 | 3.81e-01 | 90.6% | 88.5% |
| 3982720 | 2003.1.5.109 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_20 | 0.52 | 43.0 | 3.11e-01 | 88.7% | 59.3% |
| 4160544 | 295.1.1.0 ↗ | a+b two layers › ssDNA-binding transcriptional regulator domain-like › ssDNA-binding transcriptional regulator domain › ssDNA-binding transcriptional regulator domain | 0.51 | 36.0 | 3.19e-01 | 98.1% | 50.7% |
D2
high
residues 299-347_386-489
Domain cluster:
representative
CATH (12)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3c18A02 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.70 | 47.0 | 5.26e-01 | 74.5% | 87.3% |
| 1y4cA03 | 1.20.120.660 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › IL-4 antagonist (De novo design) like domain | 0.66 | 46.0 | 5.24e-01 | 74.5% | 95.6% |
| 3ihuA02 | 1.20.120.530 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › GntR ligand-binding domain-like | 0.61 | 43.0 | 4.54e-01 | 91.5% | 80.6% |
| 7c1iA01 | 1.20.120.160 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain | 0.61 | 38.0 | 4.54e-01 | 75.2% | 95.0% |
| 1r2jA03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.55 | 42.0 | 4.38e-01 | 84.3% | 85.4% |
| 2rfqC03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.54 | 44.0 | 4.26e-01 | 86.9% | 84.0% |
| 3b9qA01 | 1.20.120.140 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › SRP54, nucleotide-binding domain | 0.53 | 30.0 | 3.64e-01 | 86.3% | 89.9% |
| 3hl6A02 | 1.20.58.700 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.53 | 33.0 | 3.73e-01 | 83.7% | 82.6% |
| 4ap2B01 | 1.20.1310.10 | Mainly Alpha › Up-down Bundle › 5 helical Cullin repeat like › Cullin Repeats | 0.52 | 27.0 | 2.91e-01 | 78.4% | 56.0% |
| 1rx0A03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.52 | 42.0 | 4.27e-01 | 86.3% | 91.0% |
| 2c0uA03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.52 | 42.0 | 4.05e-01 | 85.0% | 85.2% |
| 1xzpA02 | 1.20.120.430 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › tRNA modification GTPase MnmE domain 2 | 0.51 | 41.0 | 4.00e-01 | 86.3% | 86.7% |
ECOD (12)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4969920 | 601.7.1.2 ↗ | alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain › HEPN | 0.75 | 54.0 | 5.87e-01 | 74.5% | 93.1% |
| 3976906 | 601.7.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain | 0.75 | 53.0 | 5.62e-01 | 71.9% | 96.2% |
| 4999712 | 601.7.1.20 ↗ | alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain › Abi_C | 0.73 | 52.0 | 5.49e-01 | 73.9% | 93.6% |
| 4948130 | 601.7.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain | 0.72 | 53.0 | 5.64e-01 | 75.8% | 95.6% |
| 4950656 | 601.7.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain | 0.72 | 53.0 | 5.66e-01 | 75.2% | 96.2% |
| 3962320 | 601.7.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain | 0.67 | 47.0 | 5.24e-01 | 72.5% | 95.0% |
| 3441563 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.66 | 49.0 | 4.60e-01 | 75.2% | 86.1% |
| 3325799 | 5050.1.1.1 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr | 0.63 | 45.0 | 4.93e-01 | 72.5% | 88.8% |
| 4020994 | 5069.1.1.0 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes | 0.63 | 46.0 | 4.74e-01 | 75.8% | 93.1% |
| 3529791 | 601.1.3.1 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › A middle domain of Talin 1 › Talin_middle | 0.59 | 43.0 | 4.19e-01 | 75.2% | 71.8% |
| 4624369 | 5069.1.1.15 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › Cytochrom_C_asm | 0.58 | 42.0 | 4.35e-01 | 75.8% | 99.3% |
| 5010233 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.53 | 39.0 | 2.78e-01 | 75.8% | 28.9% |
D3
medium
residues 111-209
Domain cluster:
representative
CATH (11)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1r0uA00 | 2.40.128.20 | Mainly Beta › Beta Barrel › Lipocalin › Calycin beta-barrel core domain | 0.67 | 40.0 | 3.55e-01 | 76.8% | 40.8% |
| 1pfoA02 | 3.30.1040.20 | Alpha Beta › 2-Layer Sandwich › Carboxypeptidase Inhibitor; Chain A › | 0.58 | 29.0 | 3.78e-01 | 81.8% | 88.7% |
| 1fm2B03 | 2.30.120.10 | Mainly Beta › Roll › Penicillin G acylase, beta-roll domain › Aminohydrolase, N-terminal nucleophile (Ntn) domain, beta-sheet knob region | 0.56 | 36.0 | 4.19e-01 | 85.9% | 100.0% |
| 1f0cA02 | 2.30.39.10 | Mainly Beta › Roll › Alpha-1-antitrypsin; domain 1 › Alpha-1-antitrypsin, domain 1 | 0.54 | 32.0 | 3.04e-01 | 98.0% | 48.3% |
| 6mw4A01 | 2.60.120.1290 | Mainly Beta › Sandwich › Jelly Rolls › | 0.54 | 40.0 | 3.61e-01 | 93.9% | 58.5% |
| 1c8uA01 | 3.10.129.10 | Alpha Beta › Roll › Thiol Ester Dehydrase; Chain A › Hotdog Thioesterase | 0.53 | 31.0 | 2.65e-01 | 90.9% | 36.5% |
| 6nvxB02 | 2.30.120.10 | Mainly Beta › Roll › Penicillin G acylase, beta-roll domain › Aminohydrolase, N-terminal nucleophile (Ntn) domain, beta-sheet knob region | 0.53 | 38.0 | 4.16e-01 | 89.9% | 98.7% |
| 4wksC02 | 2.30.120.10 | Mainly Beta › Roll › Penicillin G acylase, beta-roll domain › Aminohydrolase, N-terminal nucleophile (Ntn) domain, beta-sheet knob region | 0.52 | 37.0 | 4.07e-01 | 84.8% | 100.0% |
| 4i0wD02 | 2.60.120.1290 | Mainly Beta › Sandwich › Jelly Rolls › | 0.52 | 37.0 | 3.42e-01 | 93.9% | 57.7% |
| 4yfbC02 | 2.30.120.10 | Mainly Beta › Roll › Penicillin G acylase, beta-roll domain › Aminohydrolase, N-terminal nucleophile (Ntn) domain, beta-sheet knob region | 0.51 | 38.0 | 4.12e-01 | 84.8% | 100.0% |
| 1cp9B02 | 2.30.120.10 | Mainly Beta › Roll › Penicillin G acylase, beta-roll domain › Aminohydrolase, N-terminal nucleophile (Ntn) domain, beta-sheet knob region | 0.50 | 35.0 | 3.83e-01 | 89.9% | 98.6% |
ECOD (3)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1789717 | 719.1.1.0 ↗ | beta barrels › XRCC4, N-terminal domain-like › XRCC4, N-terminal domain › XRCC4, N-terminal domain | 0.51 | 32.0 | 3.65e-01 | 76.8% | 88.6% |
| 4921900 | 11.1.1.41 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › Arrestin_C | 0.50 | 38.0 | 3.27e-01 | 79.8% | 89.9% |
| 3573769 | 220.1.1.0 ↗ | beta barrels › PH domain-like › PH domain-like › PH domain-like | 0.50 | 41.0 | 3.54e-01 | 90.9% | 72.5% |
D4
medium
residues 210-260_279-298
Domain cluster:
representative
CATH (7)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2xz0D00 | 1.10.1200.10 | Mainly Alpha › Orthogonal Bundle › Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A › ACP-like | 0.58 | 40.0 | 3.87e-01 | 98.6% | 63.4% |
| 6pzjA02 | 3.30.450.20 | Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › PAS domain | 0.57 | 39.0 | 3.08e-01 | 71.8% | 73.0% |
| 2w40A01 | 3.30.420.40 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain | 0.56 | 38.0 | 2.67e-01 | 71.8% | 80.7% |
| 1emsA02 | 3.30.428.10 | Alpha Beta › 2-Layer Sandwich › HIT family, subunit A › HIT-like | 0.55 | 46.0 | 3.78e-01 | 93.0% | 66.9% |
| 1l3lA01 | 3.30.450.80 | Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › Transcription factor LuxR-like, autoinducer-binding domain | 0.55 | 38.0 | 2.83e-01 | 71.8% | 54.1% |
| 4htlA01 | 3.30.420.40 | Alpha Beta › 2-Layer Sandwich › Nucleotidyltransferase; domain 5 › ATPase, nucleotide binding domain | 0.52 | 36.0 | 3.22e-01 | 71.8% | 87.0% |
| 1m55A00 | 3.40.1310.20 | Alpha Beta › 3-Layer(aba) Sandwich › Replication Protein E1; Chain: A, › | 0.51 | 46.0 | 3.35e-01 | 100.0% | 58.0% |
ECOD (8)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4527834 | 245.2.1.1 ↗ | a+b two layers › Ribonuclease PH domain 2-like › YbaB › YbaB › YbaB_DNA_bd | 0.65 | 28.0 | 2.98e-01 | 97.2% | 44.6% |
| 3513438 | 223.1.1.0 ↗ | a+b three layers › Profilin-like › sensor domains › sensor domains | 0.64 | 29.0 | 2.66e-01 | 100.0% | 31.6% |
| 3993195 | 859.1.1.0 ↗ | a+b two layers › The spindle assembly checkpoint protein mad2 › The spindle assembly checkpoint protein mad2 › The spindle assembly checkpoint protein mad2 | 0.57 | 39.0 | 3.22e-01 | 70.4% | 38.5% |
| 3390846 | 7516.1.1.1 ↗ | a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › NTP_transferase | 0.57 | 39.0 | 2.63e-01 | 70.4% | 36.1% |
| 4380266 | 223.1.1.0 ↗ | a+b three layers › Profilin-like › sensor domains › sensor domains | 0.55 | 38.0 | 2.66e-01 | 71.8% | 55.2% |
| 3438309 | 109.4.1.1271 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › PPR, PPR_2, TPR_24 | 0.55 | 38.0 | 2.48e-01 | 71.8% | 31.5% |
| 3237990 | 633.23.1.0 ↗ | alpha bundles › Bromodomain-like › Claudin › Claudin | 0.51 | 35.0 | 2.56e-01 | 71.8% | 93.3% |
| 3503970 | 5.1.4.1 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › WD40 | 0.50 | 34.0 | 2.21e-01 | 70.4% | 27.2% |