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IMGVR_UViG_2681812914_000001-2681812914-2682132107
Arc-VirIMGVR_UViG_2681812914_000001-2681812914-2682132107
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 66-170
Domain cluster:
representative
CATH (36)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1fouA01 | 1.10.246.30 | Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › | 0.87 | 56.0 | 6.65e-01 | 91.4% | 93.2% |
| 2bnlC00 | 1.10.490.10 | Mainly Alpha › Orthogonal Bundle › Globin-like › Globins | 0.79 | 51.0 | 4.64e-01 | 93.3% | 50.7% |
| 2ktmA00 | 1.10.790.10 | Mainly Alpha › Orthogonal Bundle › Major Prion Protein › Prion/Doppel protein, beta-ribbon domain | 0.78 | 45.0 | 5.44e-01 | 76.2% | 88.2% |
| 8hk0B03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.70 | 46.0 | 4.22e-01 | 82.9% | 51.4% |
| 2jifA03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.67 | 49.0 | 4.31e-01 | 82.9% | 51.9% |
| 3ermB00 | 1.10.10.710 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › PSPTO_1197 like | 0.65 | 37.0 | 4.70e-01 | 86.7% | 93.8% |
| 7zmgL01 | 1.10.287.3510 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.63 | 41.0 | 4.67e-01 | 92.4% | 87.5% |
| 1b48A02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.63 | 40.0 | 4.03e-01 | 81.0% | 62.4% |
| 1s05A00 | 1.20.120.10 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c/b562 | 0.63 | 45.0 | 4.25e-01 | 85.7% | 61.2% |
| 1uruA01 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.62 | 50.0 | 3.97e-01 | 85.7% | 76.1% |
| 2dq0A01 | 1.10.287.40 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain | 0.61 | 49.0 | 4.94e-01 | 85.7% | 93.5% |
| 7d3uC01 | 1.10.287.3510 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.61 | 44.0 | 4.42e-01 | 93.3% | 74.8% |
| 4gf0A02 | 1.20.1050.10 | Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › | 0.60 | 40.0 | 3.97e-01 | 77.1% | 63.7% |
| 1s7bA00 | 1.10.3730.20 | Mainly Alpha › Orthogonal Bundle › ProC C-terminal domain-like fold › | 0.60 | 39.0 | 3.96e-01 | 88.6% | 65.1% |
| 5oklA01 | 1.10.246.10 | Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › | 0.60 | 40.0 | 4.15e-01 | 93.3% | 72.3% |
| 3rv0C02 | 1.10.1520.10 | Mainly Alpha › Orthogonal Bundle › Ribonuclease iii, N-terminal Endonuclease Domain; Chain A › Ribonuclease III domain | 0.60 | 39.0 | 3.52e-01 | 76.2% | 47.2% |
| 6rzqA04 | 3.90.640.10 | Alpha Beta › Alpha-Beta Complex › Actin; Chain A, domain 4 › ATPase, substrate binding domain, subdomain 4 | 0.59 | 37.0 | 4.07e-01 | 90.5% | 77.6% |
| 2hfiA00 | 1.20.120.440 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › YppE-like | 0.59 | 39.0 | 3.73e-01 | 90.5% | 56.9% |
| 3ez0C00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.59 | 48.0 | 3.80e-01 | 86.7% | 56.7% |
| 1a41A02 | 1.20.120.380 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Type 1-topoisomerase catalytic fragment, domain 2 | 0.59 | 35.0 | 3.70e-01 | 83.8% | 66.0% |
| 1bh9B00 | 1.10.20.10 | Mainly Alpha › Orthogonal Bundle › Histone, subunit A › Histone, subunit A | 0.58 | 43.0 | 4.62e-01 | 85.7% | 91.0% |
| 5svlA01 | 1.10.287.940 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › atp-gated p2x4 ion channel | 0.58 | 35.0 | 4.11e-01 | 75.2% | 91.2% |
| 3p5pA03 | 1.10.600.10 | Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase | 0.58 | 53.0 | 3.75e-01 | 100.0% | 36.4% |
| 3udcA01 | 1.10.287.1260 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.58 | 45.0 | 4.37e-01 | 88.6% | 74.8% |
| 6wxrA01 | 1.10.640.10 | Mainly Alpha › Orthogonal Bundle › Myeloperoxidase, subunit C › Haem peroxidase domain superfamily, animal type | 0.58 | 51.0 | 3.34e-01 | 98.1% | 74.9% |
| 3deeA01 | 1.10.150.690 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › DUF2063 | 0.57 | 38.0 | 4.12e-01 | 93.3% | 81.4% |
| 1ad6A00 | 1.10.472.10 | Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like | 0.54 | 47.0 | 3.92e-01 | 97.1% | 65.4% |
| 3f1xA01 | 1.10.3130.10 | Mainly Alpha › Orthogonal Bundle › serine acetyltransferase, domain 1 › serine acetyltransferase, domain 1 | 0.53 | 46.0 | 4.10e-01 | 95.2% | 89.3% |
| 1so2A00 | 1.10.1300.10 | Mainly Alpha › Orthogonal Bundle › Catalytic domain of cyclic nucleotide phosphodiesterase 4b2b › 3'5'-cyclic nucleotide phosphodiesterase, catalytic domain | 0.52 | 43.0 | 3.08e-01 | 93.3% | 60.1% |
| 4cemA00 | 1.25.40.180 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.52 | 49.0 | 3.41e-01 | 100.0% | 41.0% |
| 3vkgA08 | 1.10.472.130 | Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Dynein motor, AAA2 domain, small subdomain | 0.52 | 46.0 | 4.05e-01 | 100.0% | 75.6% |
| 3ccyA02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.51 | 38.0 | 3.48e-01 | 96.2% | 57.8% |
| 2e9xB02 | 1.20.58.1020 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.50 | 37.0 | 3.66e-01 | 94.3% | 72.5% |
| 1q5qH00 | 3.60.20.10 | Alpha Beta › 4-Layer Sandwich › Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1 › Aminohydrolase, N-terminal nucleophile (Ntn) domain | 0.50 | 38.0 | 2.94e-01 | 85.7% | 37.1% |
| 6vudA01 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.50 | 40.0 | 4.00e-01 | 100.0% | 81.7% |
| 3lynB00 | 1.20.150.10 | Mainly Alpha › Up-down Bundle › Lysin › Fertilization protein | 0.50 | 41.0 | 3.90e-01 | 95.2% | 75.0% |
ECOD (51)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4467968 | 605.4.1.0 ↗ | alpha duplicates or obligate multimers › ROP-like › ROP protein › ROP protein | 0.78 | 49.0 | 4.71e-01 | 86.7% | 55.8% |
| 4210734 | 632.22.1.1 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats › EzrA | 0.75 | 54.0 | 5.48e-01 | 82.9% | 74.3% |
| 4997481 | 633.21.1.0 ↗ | alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 | 0.72 | 43.0 | 4.44e-01 | 80.0% | 62.0% |
| 5075878 | 632.15.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Staphylococcal complement inhibitor (SCIN) › Staphylococcal complement inhibitor (SCIN) | 0.71 | 41.0 | 4.64e-01 | 85.7% | 75.0% |
| 3406569 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.70 | 46.0 | 4.12e-01 | 87.6% | 50.4% |
| 3665807 | 611.9.1.4 ↗ | alpha bundles › N-cbl like › Resistance protein (Rx) N-terminal domain › Resistance protein (Rx) N-terminal domain › Rx_N | 0.66 | 55.0 | 4.98e-01 | 86.7% | 92.6% |
| 3918623 | 174.1.1.43 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › CD20 | 0.66 | 45.0 | 4.03e-01 | 86.7% | 51.0% |
| 5077194 | 191.1.1.0 ↗ | alpha bundles › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain › Tetracyclin repressor-like, C-terminal domain | 0.65 | 49.0 | 4.70e-01 | 90.5% | 69.7% |
| 5054586 | 5058.1.1.0 ↗ | alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region | 0.64 | 42.0 | 4.27e-01 | 92.4% | 66.7% |
| 3465921 | 611.2.1.2 ↗ | alpha bundles › N-cbl like › N-terminal domain of cbl (N-cbl) › N-terminal domain of cbl (N-cbl) › Rx_N | 0.64 | 53.0 | 4.83e-01 | 87.6% | 86.7% |
| 5055115 | 4025.1.1.0 ↗ | alpha complex topology › alpha-helical domain in nickel-iron hydrogenase, large subunit › alpha-helical domain in nickel-iron hydrogenase, large subunit › alpha-helical domain in nickel-iron hydrogenase, large subunit | 0.64 | 48.0 | 3.66e-01 | 85.7% | 35.3% |
| 5010536 | 604.5.1.0 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) | 0.63 | 54.0 | 4.47e-01 | 92.4% | 75.7% |
| 3591456 | 5081.1.1.0 ↗ | alpha bundles › Rhomboid-like › Rhomboid-like › Rhomboid-like | 0.63 | 56.0 | 4.67e-01 | 100.0% | 87.9% |
| 3202893 | 109.3.1.148 ↗ | alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › Goodbye | 0.63 | 58.0 | 4.67e-01 | 100.0% | 97.4% |
| 3676423 | 174.1.1.72 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › DUF2985 | 0.63 | 52.0 | 4.22e-01 | 89.5% | 48.2% |
| 5074233 | 620.1.1.2 ↗ | alpha bundles › YfiT-like putative metal-dependent hydrolases › YfiT-like putative metal-dependent hydrolases › YfiT-like putative metal-dependent hydrolases › DinB | 0.63 | 47.0 | 4.12e-01 | 79.0% | 78.7% |
| 3592921 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.62 | 50.0 | 3.51e-01 | 85.7% | 90.7% |
| 3581305 | 604.12.1.92 ↗ | alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › Meckelin | 0.60 | 45.0 | 3.66e-01 | 80.0% | 87.8% |
| 3281002 | 1075.1.2.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › MacB transmembrane domain › FtsX | 0.60 | 43.0 | 3.53e-01 | 80.0% | 41.6% |
| 4059608 | 5076.1.1.1 ↗ | alpha complex topology › Mitochondrial ADP/ATP carrier-like › Mitochondrial ADP/ATP carrier › Mitochondrial ADP/ATP carrier › Mito_carr | 0.60 | 50.0 | 3.61e-01 | 88.6% | 86.0% |
| 3705510 | 5076.1.1.0 ↗ | alpha complex topology › Mitochondrial ADP/ATP carrier-like › Mitochondrial ADP/ATP carrier › Mitochondrial ADP/ATP carrier | 0.59 | 51.0 | 4.11e-01 | 94.3% | 48.3% |
| 3225544 | 4006.1.1.0 ↗ | alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain | 0.59 | 47.0 | 4.82e-01 | 86.7% | 88.0% |
| 4000187 | 5069.1.3.66 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits › 7TM_GPCR_Srw | 0.59 | 46.0 | 4.39e-01 | 90.5% | 70.7% |
| 3400140 | 5076.1.1.1 ↗ | alpha complex topology › Mitochondrial ADP/ATP carrier-like › Mitochondrial ADP/ATP carrier › Mitochondrial ADP/ATP carrier › Mito_carr | 0.59 | 48.0 | 3.48e-01 | 88.6% | 85.6% |
| 5051427 | 4070.1.1.2 ↗ | alpha arrays › FtsH protease domain-like › FtsH protease domain-like › FtsH protease domain-like › Peptidase_M50 | 0.59 | 52.0 | 4.05e-01 | 98.1% | 57.8% |
| 3373039 | 192.17.1.0 ↗ | alpha bundles › Long alpha-hairpin › Rabenosyn-5 Rab-binding domain-like › Rabenosyn-5 Rab-binding domain-like | 0.59 | 40.0 | 3.97e-01 | 93.3% | 65.2% |
| 4016645 | 5086.1.1.176 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › DUF202 | 0.59 | 47.0 | 4.58e-01 | 85.7% | 80.0% |
| 4936552 | 601.30.1.1 ↗ | alpha bundles › Four-helical up-and-down bundle › Helical bundle domain in hypothetical protein PH1320 › Helical bundle domain in hypothetical protein PH1320 › NOG1_N | 0.58 | 47.0 | 4.15e-01 | 86.7% | 60.0% |
| 3651471 | 5076.1.1.1 ↗ | alpha complex topology › Mitochondrial ADP/ATP carrier-like › Mitochondrial ADP/ATP carrier › Mitochondrial ADP/ATP carrier › Mito_carr | 0.58 | 49.0 | 3.57e-01 | 91.4% | 82.1% |
| 4106793 | 7023.1.1.3 ↗ | alpha bundles › helical ridge domain of D-alanyl transfer protein › helical ridge domain of D-alanyl transfer protein › helical ridge domain of D-alanyl transfer protein › MBOAT_2 | 0.58 | 48.0 | 4.23e-01 | 92.4% | 60.0% |
| 5055976 | 4126.1.1.1 ↗ | a/b three-layered sandwiches › beta-carbonic anhydrase-like › beta-carbonic anhydrase › beta-carbonic anhydrase › Pro_CA | 0.58 | 52.0 | 4.22e-01 | 100.0% | 83.5% |
| 3488092 | 5041.1.1.25 ↗ | extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › Myelin_PLP | 0.58 | 45.0 | 4.15e-01 | 82.9% | 74.1% |
| 3692494 | 633.23.1.22 ↗ | alpha bundles › Bromodomain-like › Claudin › Claudin › MARVEL | 0.58 | 43.0 | 3.86e-01 | 85.7% | 55.9% |
| 3350634 | 5076.1.1.1 ↗ | alpha complex topology › Mitochondrial ADP/ATP carrier-like › Mitochondrial ADP/ATP carrier › Mitochondrial ADP/ATP carrier › Mito_carr | 0.58 | 49.0 | 3.65e-01 | 93.3% | 43.3% |
| 3911662 | 633.23.1.1 ↗ | alpha bundles › Bromodomain-like › Claudin › Claudin › PMP22_Claudin | 0.57 | 46.0 | 3.70e-01 | 85.7% | 56.1% |
| 3265368 | 2498.1.1.11 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M48,Peptidase_M48_N | 0.57 | 48.0 | 3.22e-01 | 91.4% | 36.1% |
| 3453075 | 3543.1.1.4 ↗ | alpha complex topology › Acid-activated urea channel › Acid-activated urea channel › Acid-activated urea channel › DUF716 | 0.57 | 46.0 | 3.44e-01 | 86.7% | 89.4% |
| 4933555 | 141.1.1.3 ↗ | alpha bundles › Terpenoid synthases › Terpenoid synthases › Terpenoid synthases › UbiA | 0.57 | 48.0 | 3.47e-01 | 92.4% | 49.8% |
| 3181323 | 192.29.1.296 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › Ceramidase | 0.56 | 45.0 | 4.14e-01 | 86.7% | 67.2% |
| 3310401 | 5076.1.1.1 ↗ | alpha complex topology › Mitochondrial ADP/ATP carrier-like › Mitochondrial ADP/ATP carrier › Mitochondrial ADP/ATP carrier › Mito_carr | 0.56 | 47.0 | 3.55e-01 | 93.3% | 40.4% |
| 3678220 | 5076.1.1.1 ↗ | alpha complex topology › Mitochondrial ADP/ATP carrier-like › Mitochondrial ADP/ATP carrier › Mitochondrial ADP/ATP carrier › Mito_carr | 0.55 | 46.0 | 3.30e-01 | 93.3% | 39.4% |
| 3739454 | 192.5.1.38 ↗ | alpha bundles › Long alpha-hairpin › HR1 repeat › HR1 repeat › NEDD4_Bsd2 | 0.55 | 41.0 | 4.12e-01 | 100.0% | 79.0% |
| 3688424 | 2003.1.5.79 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_23 | 0.55 | 43.0 | 3.12e-01 | 84.8% | 45.6% |
| 4293733 | 4006.1.1.1 ↗ | alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF | 0.54 | 44.0 | 4.42e-01 | 85.7% | 90.5% |
| 4977678 | 192.1.1.50 ↗ | alpha bundles › Long alpha-hairpin › GreA transcript cleavage protein, N-terminal domain › GreA transcript cleavage protein, N-terminal domain › EMC3_TMCO1 | 0.54 | 37.0 | 3.29e-01 | 74.3% | 46.9% |
| 3391293 | 101.1.10.13 ↗ | alpha arrays › HTH › HTH › Cyclin-like › DUF3452 | 0.53 | 47.0 | 4.47e-01 | 97.1% | 82.5% |
| 3288971 | 101.1.1.30 ↗ | alpha arrays › HTH › HTH › Three-helical HTH › Sigma70_r3,Sigma70_r4 | 0.53 | 33.0 | 2.90e-01 | 81.9% | 43.3% |
| 4662266 | 109.3.1.274 ↗ | alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › DUF2868 | 0.52 | 48.0 | 3.58e-01 | 99.0% | 74.8% |
| 4992051 | 5069.1.3.1 ↗ | alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits › Sdh_cyt | 0.51 | 42.0 | 3.82e-01 | 89.5% | 73.8% |
| 3934899 | 6155.1.1.2 ↗ | alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter › PQ-loop | 0.51 | 38.0 | 3.42e-01 | 90.5% | 56.6% |
| 4506168 | 601.1.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin | 0.51 | 42.0 | 4.01e-01 | 92.4% | 80.0% |