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IMGVR_UViG_2786546169_000001-2786546169-2786838182

Arc-Vir

IMGVR_UViG_2786546169_000001-2786546169-2786838182

Identity

Kingdom:
archaea

Quality

86.1 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 8-156
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF14280.12 best DUF4365 54.7 1.70e-14 83.2% 76.1%
CATH (18)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1ob8A00 3.40.1350.10 Alpha Beta › 3-Layer(aba) Sandwich › Trna Endonuclease; Chain: A, domain 1 › 0.72 49.0 5.38e-01 85.2% 85.7%
2ostD00 3.40.1350.10 Alpha Beta › 3-Layer(aba) Sandwich › Trna Endonuclease; Chain: A, domain 1 › 0.67 48.0 5.12e-01 97.3% 83.5%
2w8mA00 3.40.1350.50 Alpha Beta › 3-Layer(aba) Sandwich › Trna Endonuclease; Chain: A, domain 1 › D212 PD-(D/E)XK nuclease, catalytic motif 0.65 53.0 5.12e-01 88.6% 77.0%
4esjA01 3.40.210.30 Alpha Beta › 3-Layer(aba) Sandwich › PvuII Endonuclease; Chain A › Dam replacing family, catalytic PD-(D/E)XK domain 0.60 45.0 4.46e-01 79.2% 74.4%
3wknF00 6.20.50.120 Special › Other non-globular › N-terminal domain of TfIIb › 0.59 20.0 3.32e-01 89.3% 91.3%
4lqeA00 3.40.1350.140 Alpha Beta › 3-Layer(aba) Sandwich › Trna Endonuclease; Chain: A, domain 1 › MepB-like 0.57 44.0 4.41e-01 79.2% 87.9%
4oc8A01 2.30.280.20 Mainly Beta › Roll › PUA domain-like › 0.57 47.0 4.16e-01 87.9% 79.1%
1i74A02 3.10.310.20 Alpha Beta › Roll › Diaminopimelate Epimerase; Chain A, domain 1 › DHHA2 domain 0.57 41.0 4.55e-01 81.2% 94.1%
3ijmA00 3.90.1570.20 Alpha Beta › Alpha-Beta Complex › tt1808, chain A › 0.57 38.0 3.91e-01 83.2% 69.2%
4ic1D00 3.90.320.10 Alpha Beta › Alpha-Beta Complex › Lambda Exonuclease; Chain A › 0.56 39.0 3.56e-01 71.8% 54.9%
4hlbA00 3.30.70.2960 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.55 34.0 4.21e-01 88.6% 98.9%
2xi5A00 3.40.91.60 Alpha Beta › 3-Layer(aba) Sandwich › Restriction Endonuclease › 0.53 37.0 3.44e-01 83.2% 57.1%
4oc8A02 3.40.1350.10 Alpha Beta › 3-Layer(aba) Sandwich › Trna Endonuclease; Chain: A, domain 1 › 0.53 36.0 3.48e-01 79.9% 59.3%
4oa3A00 3.10.310.50 Alpha Beta › Roll › Diaminopimelate Epimerase; Chain A, domain 1 › 0.53 40.0 4.11e-01 89.3% 83.0%
5dnoA00 3.10.590.10 Alpha Beta › Roll › ph1033 like fold › ph1033 like domains 0.53 40.0 3.95e-01 80.5% 92.7%
4f0qA02 3.40.1350.10 Alpha Beta › 3-Layer(aba) Sandwich › Trna Endonuclease; Chain: A, domain 1 › 0.52 36.0 3.30e-01 79.9% 53.1%
3devA02 3.10.310.30 Alpha Beta › Roll › Diaminopimelate Epimerase; Chain A, domain 1 › 0.51 37.0 4.05e-01 91.9% 95.7%
5anpA00 3.10.310.50 Alpha Beta › Roll › Diaminopimelate Epimerase; Chain A, domain 1 › 0.50 39.0 3.94e-01 81.2% 91.7%
ECOD (25)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4957206 2008.1.1.0 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like 0.71 54.0 5.67e-01 83.2% 86.7%
5010105 2008.1.1.3 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › Hjc 0.70 48.0 5.25e-01 83.2% 83.2%
3280651 2008.1.1.0 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like 0.70 58.0 5.01e-01 87.9% 59.1%
4149106 2008.1.1.3 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › Hjc 0.69 49.0 5.14e-01 85.2% 79.3%
4981147 2008.1.1.3 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › Hjc 0.66 53.0 5.17e-01 85.2% 76.4%
4293420 2008.1.1.13 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › RecU 0.65 53.0 4.78e-01 85.9% 74.0%
3839971 2008.1.1.0 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like 0.64 50.0 4.37e-01 79.9% 57.6%
4284406 2008.1.1.13 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › RecU 0.64 52.0 5.15e-01 85.9% 90.6%
4489860 2008.1.1.13 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › RecU 0.64 52.0 5.06e-01 85.9% 84.2%
4928779 2008.1.1.0 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like 0.64 51.0 5.11e-01 85.2% 87.7%
4942551 2008.1.1.59 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › PDDEXK_1 0.60 42.0 3.71e-01 71.8% 58.2%
1503110 2008.1.1.21 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › DpnI 0.60 50.0 4.81e-01 100.0% 77.9%
4967615 2008.1.1.0 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like 0.59 46.0 4.38e-01 83.2% 79.3%
1146578 2008.1.1.33 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › MepB-like 0.57 44.0 4.41e-01 79.2% 87.9%
4991854 5104.1.1.0 a+b three layers › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases 0.56 36.0 4.34e-01 79.9% 100.0%
1397885 2008.1.1.16 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › Mrr_cat 0.54 36.0 3.29e-01 79.9% 50.3%
4960647 3535.1.1.0 a+b two layers › Sex pheromone staph-cAM373 › Sex pheromone staph-cAM373 › Sex pheromone staph-cAM373 0.54 39.0 4.35e-01 74.5% 97.4%
402316 2008.1.1.65 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › L_protein_N 0.53 37.0 3.44e-01 83.2% 57.4%
3788758 63.1.1.1 beta barrels › Mannose 6-phosphate receptor domain › Mannose 6-phosphate receptor domain › Mannose 6-phosphate receptor domain › CIMR 0.53 25.0 3.27e-01 89.9% 80.0%
1147702 2008.1.1.16 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › Mrr_cat 0.53 36.0 3.48e-01 79.9% 59.6%
5070153 5104.1.1.0 a+b three layers › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases 0.53 36.0 4.06e-01 92.6% 91.3%
4168203 1143.1.1.1 beta sandwiches › beta sandwich domain in acetophenone carboxylase (Apc) alpha subunit › beta sandwich domain in acetophenone carboxylase (Apc) alpha subunit › beta sandwich domain in acetophenone carboxylase (Apc) alpha subunit › Hydant_A_C 0.52 27.0 3.54e-01 94.6% 91.3%
4008820 3105.1.1.1 a+b three layers › thylakoid acid phosphatase domain-related › thylakoid acid phosphatase domain-related › thylakoid acid phosphatase domain-related › TPM_phosphatase 0.51 39.0 4.14e-01 80.5% 97.0%
1007200 3105.1.1.1 a+b three layers › thylakoid acid phosphatase domain-related › thylakoid acid phosphatase domain-related › thylakoid acid phosphatase domain-related › TPM_phosphatase 0.51 38.0 3.87e-01 89.9% 79.3%
1918559 3105.1.1.1 a+b three layers › thylakoid acid phosphatase domain-related › thylakoid acid phosphatase domain-related › thylakoid acid phosphatase domain-related › TPM_phosphatase 0.50 39.0 3.94e-01 81.2% 91.7%
D2 medium residues 162-232
PDB
Domain cluster: representative
CATH (41)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4gpkF02 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.90 73.0 4.83e-01 84.5% 25.0%
1m5iA00 1.10.287.450 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.80 58.0 5.00e-01 76.1% 61.9%
3efzB00 1.20.190.20 Mainly Alpha › Up-down Bundle › Delta-Endotoxin; domain 1 › 14-3-3 domain 0.79 66.0 4.58e-01 90.1% 32.0%
2vq2A00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.79 58.0 4.00e-01 83.1% 25.0%
4l0rB00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.78 55.0 5.50e-01 74.6% 89.0%
6fdpA00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.77 62.0 5.08e-01 84.5% 69.2%
1nt2B02 1.10.287.660 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.77 55.0 5.68e-01 74.6% 80.6%
4yvoA00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.77 64.0 5.30e-01 88.7% 57.1%
4kvmA02 1.25.40.1010 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.77 55.0 3.80e-01 74.6% 69.0%
2crbA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.77 66.0 5.96e-01 94.4% 78.4%
4dciA00 6.10.140.1110 Special › Helix non-globular › Helix Hairpins › 0.76 54.0 4.22e-01 74.6% 46.9%
4wzxA01 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.76 62.0 6.13e-01 88.7% 96.0%
2v6yA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.75 63.0 6.27e-01 93.0% 93.3%
2l3lA01 1.20.58.1250 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Tubulin Binding Cofactor C, N-terminal domain 0.75 66.0 5.77e-01 98.6% 76.4%
3gz1A00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.75 61.0 4.74e-01 87.3% 58.3%
1yozA00 1.10.3200.10 Mainly Alpha › Orthogonal Bundle › Hypothetical protein af0941 › AF0941-like 0.73 60.0 5.16e-01 90.1% 77.0%
3uumA00 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.72 63.0 5.34e-01 100.0% 89.3%
1ydxA02 1.10.287.1120 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Bipartite methylase S protein 0.72 52.0 4.79e-01 76.1% 95.6%
2cfuA02 1.25.40.880 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Alkyl sulfatase, dimerisation domain 0.72 56.0 4.40e-01 83.1% 48.2%
2ijqA00 1.10.3450.10 Mainly Alpha › Orthogonal Bundle › Hyaluronidase domain-like › TTHA0068-like 0.72 62.0 4.85e-01 94.4% 71.0%
4h63K00 1.10.287.3490 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.71 51.0 4.61e-01 76.1% 56.1%
3teqB00 1.10.287.3550 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.71 52.0 4.57e-01 76.1% 63.4%
2vs0A00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.71 51.0 4.89e-01 76.1% 68.3%
1zpyA00 6.10.140.1960 Special › Helix non-globular › Helix Hairpins › 0.71 56.0 5.10e-01 83.1% 79.1%
4c9bB00 1.25.40.180 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.71 61.0 4.03e-01 94.4% 35.7%
1c02A00 1.20.120.160 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain 0.70 60.0 4.67e-01 100.0% 45.2%
1lrzA03 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.70 48.0 5.12e-01 73.2% 85.5%
2qffA00 1.20.1270.10 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.68 46.0 4.59e-01 73.2% 67.6%
3zciA00 1.20.58.1660 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.68 58.0 4.37e-01 100.0% 67.5%
2x2vA00 1.20.20.10 Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C 0.68 47.0 4.80e-01 71.8% 80.9%
3ihvA03 1.25.40.900 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.68 59.0 4.78e-01 100.0% 75.5%
4g1tA02 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.66 47.0 5.01e-01 87.3% 90.2%
3zsuA00 1.20.120.290 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Oxygen-evolving enhancer protein 3 (PsbQ), four-helix up-down bundle 0.65 55.0 4.77e-01 98.6% 72.9%
4o8sA02 1.20.58.1790 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › JHP933, helical tail domain 0.62 46.0 4.02e-01 81.7% 52.3%
2g3bA00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.62 49.0 3.74e-01 90.1% 78.1%
3rc3A05 1.20.58.1080 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.62 52.0 4.50e-01 94.4% 64.6%
6humG01 1.20.120.1200 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › NADH-ubiquinone/plastoquinone oxidoreductase chain 6, subunit NuoJ 0.61 53.0 4.04e-01 94.4% 96.9%
3jsbA01 1.20.1440.300 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › RNA-directed RNA polymerase L, helical domain 0.60 43.0 4.09e-01 74.6% 90.1%
3zssA02 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.59 43.0 4.17e-01 78.9% 74.7%
2x6hA01 1.25.40.70 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Phosphatidylinositol 3-kinase, accessory domain (PIK) 0.56 47.0 3.60e-01 100.0% 71.0%
3flkA00 3.40.718.10 Alpha Beta › 3-Layer(aba) Sandwich › Isopropylmalate Dehydrogenase › Isopropylmalate Dehydrogenase 0.51 43.0 2.82e-01 98.6% 19.5%
ECOD (35)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3620054 140.1.1.0 alpha bundles › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 0.83 71.0 5.15e-01 93.0% 40.0%
3641586 604.12.1.48 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › Vwaint 0.80 66.0 5.59e-01 90.1% 61.7%
3460830 604.16.1.3 alpha bundles › Spectrin repeat-like › Hypothetical membrane protein Ta0354, soluble domain › Hypothetical membrane protein Ta0354, soluble domain › Vwaint 0.80 67.0 5.83e-01 91.5% 68.6%
4018440 192.2.1.0 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin 0.80 57.0 5.11e-01 74.6% 96.8%
5060651 632.22.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats 0.78 54.0 5.33e-01 74.6% 68.0%
3447336 109.4.1.1207 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_TmcB 0.78 58.0 4.76e-01 83.1% 45.8%
3870558 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.76 67.0 5.63e-01 98.6% 93.3%
3268622 604.12.1.1 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › MIT 0.75 68.0 5.93e-01 100.0% 76.2%
5076876 604.12.1.1 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › MIT 0.75 56.0 5.45e-01 80.3% 78.8%
4947260 604.12.1.0 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.75 59.0 5.68e-01 84.5% 86.3%
5061334 632.22.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats 0.74 52.0 5.08e-01 76.1% 66.3%
4024570 604.12.1.2 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › Vta1 0.74 59.0 5.36e-01 87.3% 90.5%
5048081 604.12.1.0 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.74 67.0 6.61e-01 100.0% 100.0%
3750022 604.1.1.1 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin 0.72 63.0 5.48e-01 98.6% 94.5%
3966676 109.32.1.0 alpha superhelices › Repetitive alpha hairpins › Alkylsulfatase SdsA1 linker domain › Alkylsulfatase SdsA1 linker domain 0.72 57.0 4.98e-01 83.1% 68.0%
4549397 3755.1.1.0 alpha bundles › YscO-like › Putative type III secretion protein YscO-related › Putative type III secretion protein YscO-related 0.70 49.0 3.82e-01 76.1% 33.5%
4527308 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.70 59.0 3.99e-01 94.4% 36.6%
3357085 6155.1.1.1 alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter › MtN3_slv 0.70 59.0 5.66e-01 97.2% 100.0%
4016635 3922.1.1.0 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 0.68 49.0 4.42e-01 77.5% 59.0%
5053424 5081.1.1.1 alpha bundles › Rhomboid-like › Rhomboid-like › Rhomboid-like › Rhomboid 0.67 54.0 4.04e-01 88.7% 77.2%
4001581 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.67 54.0 4.17e-01 90.1% 75.2%
3729252 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.67 55.0 4.70e-01 90.1% 100.0%
3487591 603.1.1.169 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Mito_morph_reg 0.67 56.0 5.50e-01 98.6% 96.2%
4977760 106.1.1.0 alpha arrays › Globin-like › Globin-like › Globin-like 0.63 49.0 4.22e-01 88.7% 71.7%
3690687 622.1.1.0 alpha bundles › YvfG-like › HSC20 (HSCB), C-terminal oligomerisation domain › HSC20 (HSCB), C-terminal oligomerisation domain 0.62 51.0 5.06e-01 90.1% 97.3%
1128224 109.32.1.1 alpha superhelices › Repetitive alpha hairpins › Alkylsulfatase SdsA1 linker domain › Alkylsulfatase SdsA1 linker domain › Alkyl_sulf_dimr 0.62 49.0 4.51e-01 88.7% 64.9%
5006655 5069.1.1.2 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › Ni_hydr_CYTB 0.62 54.0 3.90e-01 100.0% 75.8%
3967960 601.1.3.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › A middle domain of Talin 1 0.61 53.0 4.29e-01 97.2% 80.0%
5079025 632.22.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats 0.61 53.0 5.33e-01 93.0% 100.0%
5051215 192.11.1.1 alpha bundles › Long alpha-hairpin › C-terminal UvrC-binding domain of UvrB › C-terminal UvrC-binding domain of UvrB › UVR 0.60 51.0 5.05e-01 100.0% 97.3%
3993765 627.1.1.0 alpha complex topology › VPS9 domain › VPS9 domain › VPS9 domain 0.59 43.0 4.15e-01 81.7% 70.6%
5062044 632.11.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like 0.57 50.0 4.86e-01 97.2% 88.7%
5059279 632.11.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like 0.57 52.0 4.98e-01 100.0% 97.5%
1422930 109.32.1.1 alpha superhelices › Repetitive alpha hairpins › Alkylsulfatase SdsA1 linker domain › Alkylsulfatase SdsA1 linker domain › Alkyl_sulf_dimr 0.57 43.0 3.93e-01 84.5% 61.6%
5069212 632.11.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like 0.53 42.0 4.42e-01 84.5% 100.0%
D3 medium residues 233-295
PDB
Domain cluster: representative
CATH (4)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3nymA00 6.10.290.10 Special › Helix non-globular › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.85 75.0 5.84e-01 93.7% 64.5%
1vmgA00 1.10.287.1080 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › MazG-like 0.81 60.0 5.47e-01 77.8% 64.6%
4x5mA00 1.20.1280.290 Mainly Alpha › Up-down Bundle › Monooxygenase › 0.79 61.0 5.46e-01 85.7% 60.5%
2f93B00 1.10.287.470 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.64 48.0 5.25e-01 84.1% 100.0%
D4 medium residues 296-360
PDB
Domain cluster: representative
CATH (8)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1z0jB00 4.10.860.20 Few Secondary Structures › Irregular › DNA Excision Repair, Uvrb; Chain A › Rabenosyn, Rab binding domain 0.85 60.0 6.69e-01 73.8% 94.1%
1yzmA00 4.10.860.20 Few Secondary Structures › Irregular › DNA Excision Repair, Uvrb; Chain A › Rabenosyn, Rab binding domain 0.84 57.0 6.62e-01 72.3% 100.0%
3r6nA02 1.20.58.1060 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.76 66.0 4.98e-01 96.9% 41.3%
2gtsA00 1.10.287.850 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain 0.76 67.0 6.34e-01 98.5% 92.2%
2lhrA00 1.20.58.1270 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.74 48.0 4.50e-01 70.8% 55.1%
3lbxB01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.70 59.0 5.15e-01 100.0% 60.7%
1grjA01 1.10.287.180 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Transcription elongation factor, GreA/GreB, N-terminal domain 0.70 57.0 5.52e-01 92.3% 85.1%
6ynwH01 1.20.20.10 Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C 0.68 59.0 5.72e-01 98.5% 94.6%
ECOD (3)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4930198 605.1.1.2 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › H-kinase_dim 0.83 66.0 6.85e-01 92.3% 91.7%
3230775 192.1.1.25 alpha bundles › Long alpha-hairpin › GreA transcript cleavage protein, N-terminal domain › GreA transcript cleavage protein, N-terminal domain › VPS18_RING_C 0.78 62.0 5.19e-01 86.2% 50.9%
4831662 5043.1.1.1 extended segments › Sensor proteins transmembrane domains › Htr2 transmembrane domain-like › Htr2 transmembrane domain-like › Htr2 0.67 56.0 5.67e-01 93.8% 92.4%
D5 medium residues 361-444
PDB
Domain cluster: representative
CATH (23)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4i1aA00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.85 73.0 4.94e-01 91.7% 28.8%
3t9jA00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.84 62.0 5.11e-01 77.4% 100.0%
2qqyA00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.81 61.0 5.11e-01 79.8% 99.3%
1s3qG00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.80 62.0 4.93e-01 82.1% 85.9%
2katA00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.80 64.0 5.73e-01 90.5% 62.6%
1qqeA00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.80 67.0 4.59e-01 91.7% 28.1%
3ma5A00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.78 62.0 6.09e-01 90.5% 78.9%
1sr2A00 1.20.120.160 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain 0.77 56.0 5.01e-01 78.6% 55.2%
3ly7A02 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.75 62.0 5.03e-01 90.5% 49.7%
1zs3A00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.75 53.0 4.16e-01 73.8% 88.9%
1bbhA00 1.20.120.10 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c/b562 0.75 56.0 4.87e-01 81.0% 80.2%
2pqrA01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.73 60.0 5.85e-01 89.3% 81.7%
7ewfA01 1.25.40.990 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.72 62.0 4.40e-01 94.0% 57.4%
3unoE00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.71 49.0 3.87e-01 71.4% 98.8%
2xgjA03 1.10.3380.30 Mainly Alpha › Orthogonal Bundle › Sec63 N-terminal domain-like fold › 0.69 53.0 3.87e-01 81.0% 95.8%
3u4tB00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.68 55.0 3.95e-01 90.5% 30.7%
4me2A00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.68 51.0 3.96e-01 90.5% 35.6%
4egwA02 1.20.58.340 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region 0.67 51.0 4.55e-01 81.0% 96.6%
8amzT01 1.25.40.990 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.62 54.0 3.89e-01 100.0% 33.0%
5jajA03 1.20.1320.30 Mainly Alpha › Up-down Bundle › phosphoenolpyruvate carboxylase, domain 3 › 0.59 53.0 4.78e-01 100.0% 93.1%
3rlfF01 1.20.58.370 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › MalF N-terminal region-like 0.59 48.0 4.77e-01 88.1% 84.9%
3r2cA00 1.10.940.10 Mainly Alpha › Orthogonal Bundle › N-utilizing Substance Protein B Homolog; Chain A › NusB-like 0.59 44.0 3.84e-01 82.1% 86.2%
4rngC00 1.20.1280.290 Mainly Alpha › Up-down Bundle › Monooxygenase › 0.55 41.0 4.20e-01 79.8% 98.8%
ECOD (27)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4999446 109.4.1.198 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_12 0.88 77.0 5.19e-01 95.2% 28.1%
4969803 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.86 74.0 5.33e-01 91.7% 35.0%
4932747 109.4.1.198 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_12 0.85 73.0 6.91e-01 95.2% 78.0%
3275782 109.4.1.244 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › RPN6_N 0.84 73.0 5.02e-01 95.2% 29.8%
4374848 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.83 72.0 4.53e-01 92.9% 50.9%
3508752 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.83 73.0 6.50e-01 95.2% 68.7%
4996068 109.4.1.210 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_19 0.83 66.0 4.50e-01 91.7% 25.8%
5049930 109.4.1.192 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_8 0.80 71.0 5.67e-01 100.0% 50.3%
4304744 109.4.1.206 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › YfiO 0.80 56.0 4.91e-01 84.5% 50.8%
3644462 109.4.1.1891 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_7, TPR_8, TPR_16 0.80 65.0 5.02e-01 100.0% 41.1%
3509325 109.4.1.235 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › SRP68 0.79 71.0 4.54e-01 100.0% 26.4%
3624841 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.76 62.0 5.63e-01 89.3% 67.0%
3341298 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.76 57.0 4.61e-01 79.8% 62.6%
3901044 109.4.1.210 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_19 0.75 64.0 5.17e-01 91.7% 49.7%
5012561 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.71 64.0 4.73e-01 100.0% 40.5%
4998434 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.71 64.0 4.00e-01 100.0% 27.7%
3277865 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.70 57.0 4.96e-01 91.7% 57.8%
4944010 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.69 56.0 5.23e-01 89.3% 78.1%
3178762 109.4.1.356 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Fungal_trans 0.68 62.0 4.65e-01 100.0% 53.7%
4962215 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.67 57.0 4.90e-01 95.2% 72.6%
5057208 632.15.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Staphylococcal complement inhibitor (SCIN) › Staphylococcal complement inhibitor (SCIN) 0.67 52.0 4.87e-01 100.0% 69.0%
None 0.65 60.0 4.02e-01 100.0% 52.0%
3659459 109.4.1.109 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Sel1 0.63 52.0 3.46e-01 94.0% 38.1%
4950248 601.1.1.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.60 48.0 4.68e-01 89.3% 85.3%
3705127 509.1.1.0 alpha bundles › PAH2 domain › PAH2 domain › PAH2 domain 0.55 46.0 4.52e-01 95.2% 89.5%
4928934 6049.1.1.0 alpha bundles › PH0832-like › PH0832-like › PH0832-like 0.54 41.0 3.67e-01 84.5% 60.8%
3979125 1075.5.1.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MatE 0.50 44.0 3.34e-01 100.0% 59.5%
D6 medium residues 445-496
PDB
Domain cluster: representative
CATH (16)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4jneA03 3.90.640.10 Alpha Beta › Alpha-Beta Complex › Actin; Chain A, domain 4 › ATPase, substrate binding domain, subdomain 4 0.75 51.0 4.26e-01 78.8% 42.0%
3d2fA04 3.90.640.10 Alpha Beta › Alpha-Beta Complex › Actin; Chain A, domain 4 › ATPase, substrate binding domain, subdomain 4 0.75 51.0 4.30e-01 78.8% 44.0%
3ragB00 3.40.50.410 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › von Willebrand factor, type A domain 0.69 52.0 3.51e-01 86.5% 53.5%
1xu0A00 1.10.790.10 Mainly Alpha › Orthogonal Bundle › Major Prion Protein › Prion/Doppel protein, beta-ribbon domain 0.63 55.0 4.40e-01 98.1% 93.1%
3fayA00 1.10.506.10 Mainly Alpha › Orthogonal Bundle › GTPase Activation - p120GAP; domain 1 › GTPase Activation - p120gap; domain 1 0.60 50.0 3.07e-01 100.0% 59.9%
4wctA01 3.50.50.60 Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain 0.60 49.0 3.28e-01 96.2% 70.8%
4i8oA03 1.10.8.1130 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Bacterial toxin RNase RnlA/LsoA, C-terminal Dmd-binding domain 0.59 38.0 3.59e-01 78.8% 50.7%
3fxdB00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.59 41.0 4.03e-01 88.5% 67.2%
4h9nC00 1.20.58.2170 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.58 48.0 3.26e-01 96.2% 23.9%
2vd5B02 1.10.510.10 Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 0.58 51.0 3.45e-01 100.0% 81.9%
4qbuA02 3.40.366.10 Alpha Beta › 3-Layer(aba) Sandwich › Malonyl-Coenzyme A Acyl Carrier Protein; domain 2 › Malonyl-Coenzyme A Acyl Carrier Protein, domain 2 0.58 49.0 3.23e-01 100.0% 58.9%
2ib0A01 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.57 49.0 3.70e-01 100.0% 83.0%
1v9mA01 1.10.132.50 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › ATP synthase (C/AC39) subunit, domain 3 0.54 46.0 3.58e-01 96.2% 47.0%
1x4oA00 1.10.10.790 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Surp module 0.52 37.0 3.44e-01 84.6% 55.1%
1ck7A01 3.40.390.10 Alpha Beta › 3-Layer(aba) Sandwich › Collagenase (Catalytic Domain) › Collagenase (Catalytic Domain) 0.51 38.0 2.52e-01 84.6% 17.9%
8igrI01 2.40.270.10 Mainly Beta › Beta Barrel › Dna-directed Rna Polymerase Ii 140kd Polypeptide; Chain: B; Domain 6 › DNA-directed RNA polymerase, subunit 2, domain 6 0.51 40.0 2.87e-01 90.4% 65.3%
ECOD (11)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4002839 2484.1.1.1 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › HSP70 0.76 52.0 3.36e-01 78.8% 17.2%
3461725 592.2.1.2 alpha arrays › PWI domain-like › YugE-like › YugE-like › WGG 0.64 49.0 3.75e-01 92.3% 35.8%
4287928 3018.1.1.0 a+b two layers › MesJ substrate recognition domain-like › MesJ substrate recognition domain-like › MesJ substrate recognition domain-like 0.63 55.0 4.63e-01 100.0% 65.6%
3390532 193.1.1.41 alpha bundles › CH domain-like › Calponin-homology domain-like › Calponin-homology domain-like › WHIM1 0.61 50.0 3.47e-01 96.2% 84.0%
3710673 2005.1.1.1 a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains › tRNA-synt_1 0.61 49.0 3.13e-01 88.5% 41.2%
3268188 386.1.1.0 few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers 0.59 42.0 4.49e-01 78.8% 100.0%
3798818 206.1.1.1 a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase 0.59 50.0 3.13e-01 100.0% 50.3%
3940154 2005.1.1.1 a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains › tRNA-synt_1 0.57 42.0 2.63e-01 86.5% 26.4%
3600130 246.3.1.1 a+b four layers › Carbon-nitrogen hydrolase-like › DNase I-like › DNase I-like › Exo_endo_phos 0.56 48.0 3.00e-01 100.0% 71.2%
3221064 174.1.1.13 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › DUF2700 0.55 45.0 3.31e-01 92.3% 33.8%
3715687 2008.1.1.0 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like 0.53 45.0 2.87e-01 98.1% 18.9%
D7 medium residues 497-592
PDB
Domain cluster: representative
CATH (2)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3euwA02 3.30.360.10 Alpha Beta › 2-Layer Sandwich › Dihydrodipicolinate Reductase; domain 2 › Dihydrodipicolinate Reductase; domain 2 0.53 41.0 3.30e-01 86.5% 73.7%
3ecqA01 2.60.120.870 Mainly Beta › Sandwich › Jelly Rolls › 0.50 37.0 3.08e-01 80.2% 61.7%