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IMGVR_UViG_2799112914_000002-2799112914-2800883601

Arc-Vir

IMGVR_UViG_2799112914_000002-2799112914-2800883601

Identity

Kingdom:
archaea

Quality

76.8 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 24-132
PDB
Domain cluster: representative
CATH (25)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2yb5F01 1.20.1280.250 Mainly Alpha › Up-down Bundle › Monooxygenase › 0.68 46.0 5.16e-01 82.6% 88.4%
3f4mA00 1.20.1440.160 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › Tumor necrosis factor alpha-induced protein 8-like 0.65 50.0 4.50e-01 81.7% 79.9%
4adnA01 1.20.1280.250 Mainly Alpha › Up-down Bundle › Monooxygenase › 0.63 45.0 5.02e-01 89.0% 95.3%
3ddhA02 1.10.150.240 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 0.62 35.0 3.99e-01 87.2% 74.1%
7c1iA01 1.20.120.160 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain 0.60 44.0 4.63e-01 80.7% 83.0%
3fmsA02 1.20.120.530 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › GntR ligand-binding domain-like 0.58 50.0 4.67e-01 98.2% 85.8%
3n2oA03 1.20.58.930 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.57 36.0 3.82e-01 86.2% 70.8%
1ug7A00 1.20.120.360 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Axin interactor, dorsalization-associated protein, N-terminal domain 0.57 47.0 4.51e-01 90.8% 89.1%
2yevA03 1.20.120.80 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c oxidase, subunit III, four-helix bundle 0.57 45.0 3.85e-01 86.2% 83.2%
2hz8A00 1.20.120.660 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › IL-4 antagonist (De novo design) like domain 0.57 43.0 4.31e-01 80.7% 91.3%
5d0yA00 1.10.1760.20 Mainly Alpha › Orthogonal Bundle › Arp2/3 complex 21 kDa subunit ARPC3 › 0.56 41.0 3.70e-01 77.1% 83.2%
6adqG01 1.20.120.80 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c oxidase, subunit III, four-helix bundle 0.56 44.0 3.82e-01 86.2% 87.1%
1q0gA00 1.20.120.400 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nickel-containing superoxide dismutase 0.56 43.0 4.21e-01 80.7% 87.2%
4hwhE00 1.20.58.120 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › BAG domain 0.56 37.0 4.14e-01 88.1% 85.2%
1oj6A00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.55 39.0 3.56e-01 72.5% 93.9%
1wgwA00 1.20.120.140 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › SRP54, nucleotide-binding domain 0.55 45.0 4.67e-01 89.9% 96.0%
3ieeA02 1.20.58.820 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Uncharacterised protein PF12889, C-terminal DUF3829 0.55 42.0 4.39e-01 80.7% 100.0%
2w53B00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.55 44.0 3.88e-01 89.9% 64.7%
1zvzA02 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.55 42.0 4.02e-01 80.7% 94.4%
1hbgA00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.54 39.0 3.57e-01 75.2% 92.5%
3uonA01 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.53 44.0 3.25e-01 89.9% 69.2%
3rfyA02 1.20.120.290 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Oxygen-evolving enhancer protein 3 (PsbQ), four-helix up-down bundle 0.53 40.0 4.09e-01 81.7% 93.5%
1jr7A00 3.60.130.10 Alpha Beta › 4-Layer Sandwich › Double-stranded beta-helix › Clavaminate synthase-like 0.52 45.0 3.31e-01 97.2% 85.9%
2i0mA02 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.51 34.0 3.59e-01 80.7% 74.3%
1cpqA00 1.20.120.10 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c/b562 0.50 39.0 3.75e-01 84.4% 95.3%
ECOD (24)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3651184 4957.1.1.7 a+b complex topology › helical domain in yeast RNA-polymerases › third helical domain in yeast RNA-polymerase II beta-prime subunit › third helical domain in yeast RNA-polymerase II beta-prime subunit › MOM1 0.61 35.0 4.02e-01 79.8% 80.0%
3646445 3615.1.1.38 alpha bundles › Bacterial dynamin-like protein helical domain › Bacterial dynamin-like protein helical domain › Bacterial dynamin-like protein helical domain › ROH1-like 0.60 47.0 3.39e-01 84.4% 85.8%
3278112 4953.1.1.25 beta barrels › L-aspartase C-terminal domain-like › L-aspartase C-terminal domain-like › L-aspartase C-terminal domain-like › DUF4226 0.60 42.0 4.27e-01 74.3% 76.4%
54382 601.1.1.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.59 46.0 4.42e-01 81.7% 92.7%
3623172 601.1.1.1 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › Vinculin 0.58 47.0 4.46e-01 87.2% 100.0%
4886107 621.1.1.3 alpha bundles › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Sey1_3HB 0.58 40.0 4.22e-01 73.4% 78.0%
3835982 181.1.1.1 alpha bundles › Domain of the SRP/SRP receptor G proteins-like › Domain of the SRP/SRP receptor G-proteins › Domain of the SRP/SRP receptor G-proteins › SRP54_N 0.57 43.0 4.55e-01 96.3% 92.6%
3898895 601.1.1.68 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › RHG29_45_N 0.57 44.0 4.37e-01 81.7% 87.0%
3998998 601.16.1.2 alpha bundles › Four-helical up-and-down bundle › FAT domain of focal adhesion kinase › FAT domain of focal adhesion kinase › Focal_AT 0.57 44.0 4.01e-01 81.7% 79.7%
3384461 601.18.1.0 alpha bundles › Four-helical up-and-down bundle › Oxygen-evolving enhancer protein 3 › Oxygen-evolving enhancer protein 3 0.56 44.0 3.85e-01 81.7% 84.4%
3652677 601.18.1.13 alpha bundles › Four-helical up-and-down bundle › Oxygen-evolving enhancer protein 3 › Oxygen-evolving enhancer protein 3 › Vwaint 0.56 45.0 4.48e-01 88.1% 88.7%
54518 601.12.1.0 alpha bundles › Four-helical up-and-down bundle › Nickel-containing superoxide dismutase, NiSOD › Nickel-containing superoxide dismutase, NiSOD 0.56 43.0 4.22e-01 80.7% 87.2%
4929553 601.18.1.33 alpha bundles › Four-helical up-and-down bundle › Oxygen-evolving enhancer protein 3 › Oxygen-evolving enhancer protein 3 › PF30769 0.55 43.0 4.44e-01 82.6% 91.0%
3554277 601.1.2.6 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › Talin_IBS2B 0.55 43.0 3.05e-01 81.7% 34.2%
3953101 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.55 45.0 3.60e-01 90.8% 84.7%
4536674 601.1.1.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.54 42.0 3.68e-01 85.3% 93.1%
3199230 604.12.1.0 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.54 42.0 4.30e-01 85.3% 92.4%
4421867 601.1.1.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.53 42.0 3.85e-01 85.3% 82.7%
3975942 601.4.1.6 alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains › TorS_sensor_domain 0.53 40.0 3.84e-01 79.8% 82.3%
3845882 621.1.1.0 alpha bundles › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain 0.52 37.0 3.44e-01 77.1% 55.9%
3733626 310.2.1.0 a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF 0.52 38.0 3.50e-01 76.1% 75.0%
3668287 601.2.1.5 alpha bundles › Four-helical up-and-down bundle › Cytochromes › Cytochromes › Ctr 0.52 35.0 3.55e-01 76.1% 69.1%
3205696 310.2.1.0 a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF 0.51 41.0 3.82e-01 86.2% 85.2%
3706405 633.16.1.0 alpha bundles › Bromodomain-like › PMT helical bundle domain-like › PMT helical bundle domain-like 0.50 32.0 3.85e-01 86.2% 100.0%
D2 high residues 136-300
PDB
Domain cluster: representative
CATH (24)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2diuA01 3.30.70.330 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain 0.63 30.0 4.28e-01 72.1% 100.0%
1yz7A02 3.30.70.1130 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › EIF_2_alpha 0.62 34.0 4.52e-01 70.9% 97.8%
2cveA02 3.30.70.240 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.60 28.0 3.90e-01 70.9% 100.0%
1j27A00 3.30.70.1120 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › TT1725-like 0.59 35.0 4.44e-01 78.2% 98.0%
5t0oA02 3.30.70.1430 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Multidrug efflux transporter AcrB pore domain 0.59 34.0 4.18e-01 72.1% 91.3%
2dt9A02 3.30.70.260 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain 0.58 30.0 4.06e-01 77.0% 100.0%
3s1tA02 3.30.70.260 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain 0.57 30.0 4.00e-01 77.0% 100.0%
6gdxA00 3.30.70.120 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.57 33.0 3.97e-01 75.2% 86.0%
3mwbB03 3.30.70.260 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain 0.57 30.0 3.85e-01 74.5% 88.4%
4bbyB04 3.30.70.3450 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.56 35.0 4.19e-01 76.4% 96.2%
3ungC01 3.30.70.2220 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › CRISPR-Cas system, Cmr2 subunit, D1 domain, cysteine cluster 0.56 51.0 4.50e-01 98.8% 95.4%
4kyzA00 3.30.70.600 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Ribosomal protein S10 0.55 30.0 3.05e-01 78.2% 49.7%
3pm9A03 3.30.70.2190 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.55 35.0 4.06e-01 84.2% 88.4%
5k9fA00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.54 34.0 4.09e-01 74.5% 99.0%
3lo3A00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.54 32.0 3.91e-01 77.0% 97.9%
1vx7X00 3.30.1360.210 Alpha Beta › 2-Layer Sandwich › Gyrase A; domain 2 › 0.54 32.0 4.02e-01 87.3% 100.0%
2fiuA00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.53 32.0 3.92e-01 78.2% 100.0%
6lpnA03 3.30.70.2190 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.53 34.0 3.92e-01 81.2% 91.2%
1vx7H01 3.90.930.12 Alpha Beta › Alpha-Beta Complex › Outer Surface Protein A; domain 3 › Ribosomal protein L6 0.53 29.0 3.79e-01 92.7% 100.0%
4g6vB00 3.30.70.2920 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.53 33.0 4.02e-01 84.8% 100.0%
3b8mC01 3.30.1890.10 Alpha Beta › 2-Layer Sandwich › Bacterial polysaccharide co-polymerase-like › FepE-like 0.51 39.0 4.06e-01 78.2% 100.0%
3bb5A00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.51 32.0 3.90e-01 77.0% 100.0%
6s2vC02 3.30.460.10 Alpha Beta › 2-Layer Sandwich › Beta Polymerase; domain 2 › Beta Polymerase, domain 2 0.51 36.0 3.84e-01 85.5% 82.8%
4nnzA02 3.30.830.10 Alpha Beta › 2-Layer Sandwich › Cytochrome Bc1 Complex; Chain A, domain 1 › Metalloenzyme, LuxS/M16 peptidase-like 0.51 38.0 3.60e-01 77.6% 91.4%
ECOD (50)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
5050850 244.1.1.0 a+b two layers › FAD-linked reductases, C-terminal domain-like › FAD-linked reductases-C › FAD-linked reductases-C 0.70 65.0 6.29e-01 100.0% 96.8%
4322692 304.162.1.1 a+b two layers › Alpha-beta plaits › Competence or damage-inducible protein CinA middle domain › Competence or damage-inducible protein CinA middle domain › CinA_KH 0.68 35.0 4.77e-01 84.8% 100.0%
4982514 304.162.1.0 a+b two layers › Alpha-beta plaits › Competence or damage-inducible protein CinA middle domain › Competence or damage-inducible protein CinA middle domain 0.66 32.0 4.57e-01 90.9% 100.0%
4398464 304.162.1.1 a+b two layers › Alpha-beta plaits › Competence or damage-inducible protein CinA middle domain › Competence or damage-inducible protein CinA middle domain › CinA_KH 0.66 34.0 4.60e-01 83.6% 100.0%
4616494 304.162.1.1 a+b two layers › Alpha-beta plaits › Competence or damage-inducible protein CinA middle domain › Competence or damage-inducible protein CinA middle domain › CinA_KH 0.66 34.0 4.58e-01 84.8% 100.0%
4589697 304.162.1.1 a+b two layers › Alpha-beta plaits › Competence or damage-inducible protein CinA middle domain › Competence or damage-inducible protein CinA middle domain › CinA_KH 0.65 34.0 4.56e-01 70.3% 100.0%
4999750 304.43.1.0 a+b two layers › Alpha-beta plaits › Hypothetical protein TT1725 › Hypothetical protein TT1725 0.63 36.0 4.59e-01 78.2% 97.9%
4679312 304.162.1.1 a+b two layers › Alpha-beta plaits › Competence or damage-inducible protein CinA middle domain › Competence or damage-inducible protein CinA middle domain › CinA_KH 0.62 32.0 4.35e-01 83.6% 100.0%
4679600 304.60.1.2 a+b two layers › Alpha-beta plaits › Ribosomal protein L10-like › Ribosomal protein L10-like › Ribosomal_L10 0.61 38.0 3.99e-01 85.5% 65.8%
3602951 304.39.1.1 a+b two layers › Alpha-beta plaits › Mechanosensitive channel protein MscS (YggB), C-terminal domain › Mechanosensitive channel protein MscS (YggB), C-terminal domain › MS_channel_3rd 0.61 35.0 4.35e-01 87.9% 90.5%
4561218 304.113.1.1 a+b two layers › Alpha-beta plaits › Alpha subunit of glutamate synthase, insertion domain › Alpha subunit of glutamate synthase, insertion domain › GATase_2 0.59 37.0 4.33e-01 70.3% 86.7%
4053535 304.24.1.0 a+b two layers › Alpha-beta plaits › EF-G C-terminal domain-like › EF-G C-terminal domain-like 0.59 33.0 4.10e-01 72.7% 91.6%
4552747 304.113.1.1 a+b two layers › Alpha-beta plaits › Alpha subunit of glutamate synthase, insertion domain › Alpha subunit of glutamate synthase, insertion domain › GATase_2 0.59 37.0 4.39e-01 70.9% 90.4%
3178234 304.117.1.1 a+b two layers › Alpha-beta plaits › Ferredoxin-like domain in YebC › Ferredoxin-like domain in YebC › Transcrip_reg 0.59 33.0 4.22e-01 74.5% 98.9%
3957166 304.43.1.0 a+b two layers › Alpha-beta plaits › Hypothetical protein TT1725 › Hypothetical protein TT1725 0.58 34.0 4.28e-01 77.6% 97.9%
3972831 3016.1.1.0 a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases 0.58 29.0 3.78e-01 89.1% 90.0%
4159687 304.58.1.0 a+b two layers › Alpha-beta plaits › FepE-like › FepE-like 0.58 44.0 3.62e-01 78.2% 99.6%
4331892 304.113.1.1 a+b two layers › Alpha-beta plaits › Alpha subunit of glutamate synthase, insertion domain › Alpha subunit of glutamate synthase, insertion domain › GATase_2 0.58 37.0 4.37e-01 70.3% 92.2%
3947199 304.126.1.5 a+b two layers › Alpha-beta plaits › ferredoxin-like domain in vacuolar ATP synthase subunit C › ferredoxin-like domain in vacuolar ATP synthase subunit C › PrmA 0.58 34.0 4.19e-01 75.8% 95.0%
3941324 327.11.2.11 a+b two layers › Alpha-lytic protease prodomain-like › KH-domains › Eukaryotic type KH-domain (KH-domain type I) › KH_1_3 0.56 40.0 4.43e-01 77.6% 92.3%
3967050 304.58.1.0 a+b two layers › Alpha-beta plaits › FepE-like › FepE-like 0.56 42.0 3.38e-01 78.2% 100.0%
3767943 304.6.1.1 a+b two layers › Alpha-beta plaits › FAD-linked oxidases, C-terminal domain › FAD-linked oxidases, C-terminal domain › FAD-oxidase_C 0.56 34.0 3.29e-01 77.0% 51.3%
3643801 304.113.1.1 a+b two layers › Alpha-beta plaits › Alpha subunit of glutamate synthase, insertion domain › Alpha subunit of glutamate synthase, insertion domain › GATase_2 0.56 40.0 3.65e-01 87.3% 56.3%
3692240 304.4.1.0 a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel 0.55 37.0 4.20e-01 75.2% 91.7%
5005971 304.48.1.31 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › Cas10-Cmr2_palm2 0.55 45.0 3.03e-01 87.3% 37.1%
5026676 304.6.1.1 a+b two layers › Alpha-beta plaits › FAD-linked oxidases, C-terminal domain › FAD-linked oxidases, C-terminal domain › FAD-oxidase_C 0.55 35.0 3.09e-01 76.4% 41.2%
4388112 304.5.1.18 a+b two layers › Alpha-beta plaits › GlnB-like › GlnB-like › PrmA 0.55 33.0 4.01e-01 75.8% 93.3%
5077294 329.1.1.2 a+b two layers › Prokaryotic AspRS, insert domain › Prokaryotic AspRS, insert domain › Prokaryotic AspRS, insert domain › DUF4443 0.55 33.0 4.17e-01 90.9% 100.0%
3962099 304.4.1.0 a+b two layers › Alpha-beta plaits › Dimeric alpha+beta barrel › Dimeric alpha+beta barrel 0.55 33.0 4.05e-01 75.8% 94.3%
4980299 304.6.1.0 a+b two layers › Alpha-beta plaits › FAD-linked oxidases, C-terminal domain › FAD-linked oxidases, C-terminal domain 0.55 34.0 3.00e-01 80.0% 40.0%
5022760 304.48.1.31 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › Cas10-Cmr2_palm2 0.54 49.0 3.63e-01 98.2% 48.1%
5000138 304.6.1.1 a+b two layers › Alpha-beta plaits › FAD-linked oxidases, C-terminal domain › FAD-linked oxidases, C-terminal domain › FAD-oxidase_C 0.54 33.0 2.98e-01 80.0% 40.4%
3301489 304.9.1.0 a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD 0.54 34.0 4.00e-01 83.0% 93.6%
4980941 304.6.1.1 a+b two layers › Alpha-beta plaits › FAD-linked oxidases, C-terminal domain › FAD-linked oxidases, C-terminal domain › FAD-oxidase_C 0.54 34.0 3.04e-01 81.8% 41.2%
3955802 304.6.1.1 a+b two layers › Alpha-beta plaits › FAD-linked oxidases, C-terminal domain › FAD-linked oxidases, C-terminal domain › FAD-oxidase_C 0.53 34.0 3.05e-01 76.4% 43.3%
4947319 304.6.1.1 a+b two layers › Alpha-beta plaits › FAD-linked oxidases, C-terminal domain › FAD-linked oxidases, C-terminal domain › FAD-oxidase_C 0.53 34.0 2.99e-01 81.2% 41.8%
5073072 304.6.1.1 a+b two layers › Alpha-beta plaits › FAD-linked oxidases, C-terminal domain › FAD-linked oxidases, C-terminal domain › FAD-oxidase_C 0.53 36.0 3.18e-01 76.4% 45.6%
4433350 304.28.1.13 a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain › MMPL 0.53 32.0 3.92e-01 70.3% 100.0%
3930715 327.11.2.11 a+b two layers › Alpha-lytic protease prodomain-like › KH-domains › Eukaryotic type KH-domain (KH-domain type I) › KH_1_3 0.53 39.0 4.28e-01 78.2% 94.6%
4996585 304.6.1.1 a+b two layers › Alpha-beta plaits › FAD-linked oxidases, C-terminal domain › FAD-linked oxidases, C-terminal domain › FAD-oxidase_C 0.53 34.0 3.00e-01 83.0% 41.6%
4953444 304.8.1.111 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › MCR_D 0.53 33.0 3.55e-01 75.8% 72.5%
3592806 304.34.1.0 a+b two layers › Alpha-beta plaits › Nucleoside diphosphate kinases › Nucleoside diphosphate kinases 0.52 39.0 4.27e-01 76.4% 98.5%
5049918 304.6.1.1 a+b two layers › Alpha-beta plaits › FAD-linked oxidases, C-terminal domain › FAD-linked oxidases, C-terminal domain › FAD-oxidase_C 0.52 34.0 3.01e-01 76.4% 42.4%
5052311 304.8.1.0 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like 0.52 32.0 3.89e-01 70.3% 100.0%
3511125 304.6.1.1 a+b two layers › Alpha-beta plaits › FAD-linked oxidases, C-terminal domain › FAD-linked oxidases, C-terminal domain › FAD-oxidase_C 0.51 36.0 3.13e-01 83.6% 46.4%
5048812 304.6.1.1 a+b two layers › Alpha-beta plaits › FAD-linked oxidases, C-terminal domain › FAD-linked oxidases, C-terminal domain › FAD-oxidase_C 0.51 35.0 2.96e-01 77.6% 41.1%
4438218 304.8.1.0 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like 0.51 34.0 3.97e-01 79.4% 100.0%
4940105 309.1.1.14 a+b two layers › LuxS, MPP, ThrRS/AlaRS common domain › LuxS, MPP, ThrRS/AlaRS common domain › LuxS/MPP-like metallohydrolase › MZB 0.51 31.0 3.27e-01 100.0% 65.2%
4073600 331.2.1.1 a+b two layers › TBP-like › Phosphoglucomutase, C-terminal domain › Phosphoglucomutase, C-terminal domain › PGM_PMM_IV 0.50 32.0 3.92e-01 89.1% 98.2%
5048262 304.6.1.0 a+b two layers › Alpha-beta plaits › FAD-linked oxidases, C-terminal domain › FAD-linked oxidases, C-terminal domain 0.50 37.0 3.17e-01 76.4% 46.8%
D3 high residues 324-431
PDB
Domain cluster: representative
CATH (27)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4nqfA00 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.72 60.0 5.46e-01 90.7% 79.3%
2hsbA00 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.70 56.0 5.39e-01 86.1% 84.9%
1ylmA00 1.20.120.580 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › bsu32300-like 0.70 60.0 5.49e-01 93.5% 85.9%
2q00B00 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.69 55.0 5.27e-01 84.3% 90.2%
1v4aA03 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.68 51.0 4.59e-01 80.6% 85.6%
3t46A00 1.20.1270.10 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.63 42.0 4.90e-01 99.1% 97.3%
2f33A01 1.10.238.10 Mainly Alpha › Orthogonal Bundle › Recoverin; domain 1 › EF-hand 0.62 30.0 3.55e-01 72.2% 66.2%
1wn0A00 1.20.120.160 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain 0.61 40.0 3.81e-01 89.8% 55.7%
2hpsA00 1.10.238.10 Mainly Alpha › Orthogonal Bundle › Recoverin; domain 1 › EF-hand 0.59 47.0 4.02e-01 88.0% 67.9%
2qffA00 1.20.1270.10 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.59 38.0 4.43e-01 79.6% 95.9%
2xzmO02 1.10.287.10 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › S15/NS1, RNA-binding 0.59 32.0 3.85e-01 72.2% 81.4%
1qguB04 1.20.89.10 Mainly Alpha › Up-down Bundle › Nitrogenase Molybdenum-iron Protein, subunit B; domain 4 › Nitrogenase Molybdenum-iron Protein, subunit B, domain 4 0.56 31.0 3.52e-01 90.7% 69.9%
2rt6A00 1.20.1270.340 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.56 46.0 4.84e-01 97.2% 99.0%
7e4gA01 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.56 43.0 3.58e-01 82.4% 93.9%
3owaA03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.56 47.0 4.02e-01 91.7% 82.5%
4id0A02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.56 34.0 3.38e-01 78.7% 57.1%
5zw7A03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.55 46.0 4.11e-01 90.7% 71.7%
4kc9A02 1.20.120.1750 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.55 46.0 3.65e-01 96.3% 44.8%
5af7B03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.54 45.0 4.08e-01 90.7% 73.6%
1siqA03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.53 44.0 3.97e-01 91.7% 74.2%
1rx0A03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.53 44.0 3.96e-01 90.7% 71.6%
4nn1A00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.53 37.0 3.00e-01 71.3% 51.2%
4x28C03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.53 44.0 4.06e-01 92.6% 79.0%
2x1lA03 1.10.730.10 Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 0.52 46.0 3.93e-01 100.0% 60.5%
4e40A00 1.20.1260.80 Mainly Alpha › Up-down Bundle › Ferritin › 0.52 44.0 3.39e-01 92.6% 82.9%
6z74C02 1.20.120.530 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › GntR ligand-binding domain-like 0.52 40.0 3.57e-01 99.1% 56.6%
6t0bc02 1.20.120.80 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c oxidase, subunit III, four-helix bundle 0.51 42.0 3.52e-01 89.8% 59.2%
ECOD (38)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
5050851 601.7.1.0 alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain 0.88 84.0 7.79e-01 100.0% 83.1%
4929723 601.7.1.0 alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain 0.82 76.0 6.69e-01 100.0% 70.3%
5004861 601.7.1.0 alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain 0.73 57.0 5.94e-01 83.3% 99.0%
4994061 601.7.1.1 alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain › HepT-like 0.72 61.0 5.54e-01 91.7% 89.5%
5081529 3931.1.1.0 alpha bundles › MtlR-like › MtlR-like › MtlR-like 0.71 58.0 5.33e-01 85.2% 83.0%
4032006 601.7.1.1 alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain › HepT-like 0.71 60.0 5.58e-01 91.7% 83.7%
5077593 601.7.1.1 alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain › HepT-like 0.71 57.0 5.21e-01 88.0% 87.6%
5029372 601.7.1.2 alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain › HEPN 0.71 56.0 5.32e-01 85.2% 83.6%
5031714 601.7.1.2 alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain › HEPN 0.70 53.0 5.44e-01 79.6% 88.5%
4967550 601.7.1.1 alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain › HepT-like 0.69 56.0 5.19e-01 86.1% 85.9%
4933023 601.7.1.1 alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain › HepT-like 0.68 59.0 5.24e-01 93.5% 84.0%
3617723 7515.1.1.19 a/b three-layered sandwiches › Alkaline phosphatase-like › Alkaline phosphatase-like › Alkaline phosphatase-like › Sulfatase, Phosphodiest 0.66 44.0 3.11e-01 88.0% 21.1%
5039571 601.7.1.0 alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain 0.66 54.0 4.30e-01 88.0% 51.6%
5031295 601.7.1.1 alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain › HepT-like 0.65 58.0 5.33e-01 97.2% 85.7%
5029781 601.7.1.0 alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain 0.64 51.0 5.18e-01 86.1% 97.1%
4484278 601.7.1.48 alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain › PF29375 0.64 50.0 4.86e-01 84.3% 80.0%
5058510 601.7.1.0 alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain 0.63 50.0 4.97e-01 84.3% 90.0%
5045789 601.7.1.0 alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain 0.62 46.0 4.95e-01 77.8% 98.9%
4970859 601.28.1.0 alpha bundles › Four-helical up-and-down bundle › VPS28 C-terminal domain-like › VPS28 C-terminal domain-like 0.62 43.0 4.45e-01 88.0% 77.0%
3487517 109.4.1.1375 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_SYVN1_N 0.61 43.0 3.36e-01 73.1% 78.3%
3646269 148.1.3.0 alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain 0.60 39.0 4.13e-01 100.0% 74.7%
5036461 632.11.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like 0.60 45.0 4.85e-01 88.0% 94.4%
5031855 632.15.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Staphylococcal complement inhibitor (SCIN) › Staphylococcal complement inhibitor (SCIN) 0.60 42.0 4.69e-01 88.0% 97.5%
4949602 601.7.1.34 alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain › DUF4129 0.58 44.0 4.65e-01 82.4% 92.6%
3243151 601.7.1.0 alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain 0.58 51.0 4.60e-01 100.0% 74.8%
3623448 633.6.1.1 alpha bundles › Bromodomain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA_dh_1 0.57 47.0 4.04e-01 89.8% 63.5%
4030141 103.4.1.0 alpha arrays › RuvA-C › Elongation factor TFIIS domain 2/ Kix domain of creb binding protein › Elongation factor TFIIS domain 2/ Kix domain of creb binding protein 0.56 44.0 4.46e-01 88.0% 81.8%
4978581 3684.1.1.0 alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like 0.55 39.0 4.09e-01 88.9% 81.0%
4032361 5039.1.1.2 alpha bundles › Cytochrome c oxidase subunit III-like › Cytochrome c oxidase subunit III-like › Cytochrome c oxidase subunit III-like › DUF420 0.54 44.0 4.14e-01 88.9% 87.4%
3491897 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.54 46.0 3.88e-01 93.5% 78.4%
3967016 633.6.1.1 alpha bundles › Bromodomain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA_dh_1 0.54 45.0 3.92e-01 91.7% 69.7%
5005724 3755.3.1.637 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › DUF7121 0.53 37.0 2.99e-01 73.1% 35.3%
1824764 1189.1.1.4 alpha bundles › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › VSG (variant surface glycoprotein) N-terminal domain and haptoglobin-hemoglobin receptor › HpHbR 0.53 44.0 3.38e-01 89.8% 81.1%
4656331 611.1.1.0 alpha bundles › N-cbl like › Transferrin receptor ectodomain, C-terminal domain › Transferrin receptor ectodomain, C-terminal domain 0.52 47.0 4.16e-01 100.0% 79.4%
4957532 3755.3.1.637 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › DUF7121 0.52 38.0 3.60e-01 75.9% 66.2%
3442404 192.11.1.0 alpha bundles › Long alpha-hairpin › C-terminal UvrC-binding domain of UvrB › C-terminal UvrC-binding domain of UvrB 0.52 39.0 3.12e-01 99.1% 38.4%
3379189 611.9.1.4 alpha bundles › N-cbl like › Resistance protein (Rx) N-terminal domain › Resistance protein (Rx) N-terminal domain › Rx_N 0.52 43.0 3.99e-01 91.7% 74.3%
3646106 140.1.1.4 alpha bundles › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › tRNA-synt_1e,DALR_2 0.51 41.0 3.39e-01 99.1% 48.2%