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IMGVR_UViG_2799112921_000001-2799112921-2800896417
Arc-VirIMGVR_UViG_2799112921_000001-2799112921-2800896417
Identity
- Kingdom:
- archaea
Quality
93.9
mean pLDDT
Cluster
Singleton — not in a non-trivial cluster
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
medium
residues 8-87
Domain cluster:
representative
CATH (76)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 6r1nA01 | 1.10.287.40 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain | 0.87 | 65.0 | 5.89e-01 | 100.0% | 60.2% |
| 4iggA01 | 1.10.287.160 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat | 0.86 | 61.0 | 6.61e-01 | 98.8% | 88.1% |
| 1ydxA02 | 1.10.287.1120 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Bipartite methylase S protein | 0.80 | 61.0 | 5.81e-01 | 100.0% | 70.0% |
| 1zkeA00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.80 | 71.0 | 7.10e-01 | 100.0% | 93.8% |
| 6vddA02 | 1.20.1060.10 | Mainly Alpha › Up-down Bundle › Taq DNA Polymerase; Chain T, domain 4 › Taq DNA Polymerase; Chain T, domain 4 | 0.79 | 73.0 | 6.39e-01 | 98.8% | 91.3% |
| 1sziA02 | 1.20.120.340 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Flagellar protein FliS | 0.79 | 60.0 | 4.95e-01 | 98.8% | 46.7% |
| 1bdp002 | 1.20.1060.10 | Mainly Alpha › Up-down Bundle › Taq DNA Polymerase; Chain T, domain 4 › Taq DNA Polymerase; Chain T, domain 4 | 0.78 | 72.0 | 6.40e-01 | 98.8% | 89.9% |
| 1t72A01 | 1.20.58.220 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 | 0.77 | 56.0 | 4.89e-01 | 100.0% | 52.1% |
| 3lnnB03 | 1.10.287.470 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.77 | 61.0 | 6.64e-01 | 95.0% | 100.0% |
| 1sj8A02 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.75 | 64.0 | 5.48e-01 | 91.3% | 95.1% |
| 2ic6A00 | 1.20.58.90 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.75 | 63.0 | 6.67e-01 | 97.5% | 100.0% |
| 2bdeA03 | 1.20.58.1160 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.74 | 56.0 | 5.69e-01 | 97.5% | 83.1% |
| 1fs0G02 | 1.10.287.80 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ATP synthase, gamma subunit, helix hairpin domain | 0.73 | 66.0 | 6.32e-01 | 100.0% | 85.4% |
| 6h9xA01 | 1.10.287.40 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain | 0.73 | 65.0 | 5.92e-01 | 98.8% | 73.5% |
| 1j5wA02 | 1.20.58.180 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Class II aaRS and biotin synthetases; domain 2 | 0.73 | 50.0 | 5.10e-01 | 100.0% | 72.7% |
| 4neoA00 | 1.10.1200.10 | Mainly Alpha › Orthogonal Bundle › Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A › ACP-like | 0.73 | 52.0 | 5.18e-01 | 75.0% | 95.2% |
| 1a36A04 | 1.10.132.10 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › | 0.72 | 62.0 | 4.70e-01 | 100.0% | 41.7% |
| 6q45G01 | 1.10.287.80 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ATP synthase, gamma subunit, helix hairpin domain | 0.71 | 64.0 | 5.15e-01 | 100.0% | 52.7% |
| 3aeiA00 | 1.10.287.370 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.71 | 67.0 | 6.31e-01 | 100.0% | 88.3% |
| 4dylA02 | 1.10.287.160 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat | 0.71 | 67.0 | 6.28e-01 | 100.0% | 88.3% |
| 4gzrB00 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.70 | 58.0 | 5.89e-01 | 100.0% | 92.2% |
| 2xseA00 | 1.20.120.1440 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › JBP1, DNA-binding domain | 0.70 | 52.0 | 4.20e-01 | 100.0% | 40.3% |
| 6qumQ00 | 1.20.20.10 | Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C | 0.70 | 48.0 | 5.03e-01 | 100.0% | 78.4% |
| 3i9wA00 | 1.20.58.920 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.69 | 64.0 | 4.27e-01 | 97.5% | 78.9% |
| 2dq0A01 | 1.10.287.40 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain | 0.69 | 63.0 | 5.61e-01 | 98.8% | 72.0% |
| 4p9tA01 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.69 | 53.0 | 4.64e-01 | 98.8% | 55.0% |
| 6gy8A01 | 1.20.1170.10 | Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › | 0.68 | 60.0 | 3.99e-01 | 100.0% | 81.3% |
| 3nrxA00 | 1.20.58.1520 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.67 | 59.0 | 5.05e-01 | 96.2% | 61.0% |
| 1wa8A00 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.67 | 52.0 | 4.85e-01 | 100.0% | 66.7% |
| 4aflA00 | 6.10.140.1740 | Special › Helix non-globular › Helix Hairpins › | 0.67 | 62.0 | 5.66e-01 | 100.0% | 86.3% |
| 3terA00 | 1.10.287.3550 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.67 | 56.0 | 4.89e-01 | 100.0% | 60.5% |
| 2ke4A00 | 6.10.140.470 | Special › Helix non-globular › Helix Hairpins › | 0.67 | 63.0 | 5.80e-01 | 100.0% | 88.8% |
| 1rfyB00 | 1.10.287.160 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat | 0.67 | 57.0 | 5.51e-01 | 91.3% | 81.8% |
| 3ofnY00 | 1.10.287.80 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ATP synthase, gamma subunit, helix hairpin domain | 0.67 | 62.0 | 5.43e-01 | 100.0% | 89.6% |
| 1f45B00 | 1.20.1250.10 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › | 0.67 | 61.0 | 5.09e-01 | 100.0% | 81.2% |
| 3tbiB02 | 6.10.140.1670 | Special › Helix non-globular › Helix Hairpins › | 0.67 | 55.0 | 5.13e-01 | 92.5% | 72.0% |
| 3c1yA02 | 1.20.1260.110 | Mainly Alpha › Up-down Bundle › Ferritin › DNA integrity scanning linker region | 0.67 | 57.0 | 4.57e-01 | 93.8% | 49.3% |
| 2rd0B00 | 1.10.287.1490 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.67 | 58.0 | 4.76e-01 | 100.0% | 54.0% |
| 1l8dA00 | 1.10.287.510 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.67 | 62.0 | 5.66e-01 | 100.0% | 77.7% |
| 2qe7G01 | 1.10.287.80 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ATP synthase, gamma subunit, helix hairpin domain | 0.66 | 58.0 | 5.45e-01 | 100.0% | 78.4% |
| 6xm1A02 | 3.90.830.10 | Alpha Beta › Alpha-Beta Complex › Syntaxin Binding Protein 1; Chain A, domain 2 › Sec1/Munc18 (SM) protein, domain 3a | 0.66 | 53.0 | 4.71e-01 | 100.0% | 61.1% |
| 2gtsA00 | 1.10.287.850 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain | 0.66 | 54.0 | 5.56e-01 | 98.8% | 92.2% |
| 3icxA01 | 1.10.287.660 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.66 | 57.0 | 5.86e-01 | 98.8% | 98.7% |
| 3cqxC00 | 1.20.58.890 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.66 | 54.0 | 5.41e-01 | 92.5% | 84.0% |
| 3r84B00 | 6.10.280.160 | Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Mediator of RNA polymerase II transcription subunit 22 | 0.65 | 55.0 | 5.56e-01 | 100.0% | 91.3% |
| 3okqA00 | 1.20.58.1540 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Actin interacting protein 3, C-terminal domain | 0.65 | 60.0 | 5.10e-01 | 100.0% | 68.0% |
| 2odvA01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.65 | 59.0 | 5.20e-01 | 97.5% | 68.8% |
| 2fzlA02 | 6.10.140.1180 | Special › Helix non-globular › Helix Hairpins › | 0.65 | 47.0 | 5.13e-01 | 76.2% | 100.0% |
| 4lwsA00 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.65 | 60.0 | 5.53e-01 | 100.0% | 86.0% |
| 4jioA01 | 1.20.120.560 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › alix/aip1 in complex with the ypdl late domain | 0.65 | 60.0 | 4.68e-01 | 100.0% | 55.9% |
| 3tulB00 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.65 | 59.0 | 4.92e-01 | 100.0% | 62.4% |
| 6vq6G02 | 1.20.1460.10 | Mainly Alpha › Up-down Bundle › subunit c (vma5p) of the yeast v-atpase, domain 2 › subunit c (vma5p) of the yeast v-atpase, domain 2 | 0.64 | 55.0 | 4.29e-01 | 97.5% | 93.5% |
| 1s35A02 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.64 | 57.0 | 5.05e-01 | 95.0% | 69.1% |
| 1uurA01 | 1.20.58.240 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › STAT; domain 1 | 0.64 | 53.0 | 4.79e-01 | 100.0% | 66.4% |
| 2gd5A00 | 6.10.140.1230 | Special › Helix non-globular › Helix Hairpins › | 0.64 | 58.0 | 4.74e-01 | 100.0% | 57.7% |
| 6ynwH01 | 1.20.20.10 | Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C | 0.63 | 48.0 | 4.98e-01 | 100.0% | 86.5% |
| 3teqB00 | 1.10.287.3550 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › | 0.63 | 50.0 | 4.71e-01 | 100.0% | 70.3% |
| 2oexA02 | 1.20.140.50 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › alix/aip1 like domains | 0.62 | 56.0 | 4.15e-01 | 98.8% | 40.6% |
| 2wgmA01 | 1.20.20.10 | Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C | 0.62 | 46.0 | 4.64e-01 | 98.8% | 78.0% |
| 2i7uA00 | 6.10.250.1010 | Special › Helix non-globular › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › | 0.62 | 45.0 | 5.02e-01 | 91.3% | 100.0% |
| 3nvoB02 | 1.20.58.340 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Magnesium transport protein CorA, transmembrane region | 0.61 | 55.0 | 4.84e-01 | 97.5% | 72.4% |
| 1fntc01 | 1.20.120.180 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Proteasome activator pa28, C-terminal domain | 0.61 | 56.0 | 4.18e-01 | 100.0% | 52.1% |
| 6vudA01 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.60 | 45.0 | 4.05e-01 | 78.8% | 94.5% |
| 1m5iA00 | 1.10.287.450 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin | 0.60 | 54.0 | 4.92e-01 | 100.0% | 80.0% |
| 3fppA03 | 6.10.140.1990 | Special › Helix non-globular › Helix Hairpins › | 0.60 | 53.0 | 5.20e-01 | 98.8% | 95.5% |
| 1nu7D01 | 1.20.120.750 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Staphylcoagulase, helix bundle domain 1 | 0.57 | 49.0 | 4.10e-01 | 92.5% | 64.4% |
| 2vs0A00 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.57 | 49.0 | 4.93e-01 | 97.5% | 97.6% |
| 6q3wB02 | 3.30.70.890 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › GHMP kinase, C-terminal domain | 0.57 | 50.0 | 3.98e-01 | 100.0% | 91.0% |
| 3kb9A00 | 1.10.600.10 | Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase | 0.56 | 48.0 | 3.24e-01 | 98.8% | 87.6% |
| 4fwvA02 | 1.20.120.1680 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.56 | 48.0 | 4.10e-01 | 97.5% | 73.1% |
| 2icwG02 | 1.10.10.530 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › mam-mhc complex, Chain D, Domain 2 | 0.55 | 38.0 | 3.66e-01 | 73.8% | 62.9% |
| 4w4kA00 | 1.10.287.850 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain | 0.55 | 48.0 | 4.84e-01 | 98.8% | 93.9% |
| 3favD00 | 1.10.287.1060 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like | 0.55 | 46.0 | 4.66e-01 | 97.5% | 96.2% |
| 3ibpA01 | 1.20.58.850 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.54 | 42.0 | 4.40e-01 | 87.5% | 95.8% |
| 3nb0B03 | 6.10.260.10 | Special › Helix non-globular › F1FO ATP Synthase › | 0.53 | 47.0 | 4.66e-01 | 98.8% | 94.0% |
| 1vt0M02 | 1.10.1740.160 | Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › | 0.53 | 34.0 | 3.37e-01 | 95.0% | 57.8% |
ECOD (73)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5064482 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.88 | 64.0 | 4.91e-01 | 100.0% | 37.0% |
| 3579763 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.81 | 70.0 | 6.18e-01 | 100.0% | 66.4% |
| 3239087 | 192.7.1.0 ↗ | alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm | 0.80 | 69.0 | 5.99e-01 | 100.0% | 62.6% |
| 4358 | 605.6.1.1 ↗ | alpha duplicates or obligate multimers › ROP-like › HP1531-like › HP1531-like › DUF2443 | 0.80 | 71.0 | 7.17e-01 | 100.0% | 96.2% |
| 4182291 | 223.1.1.5 ↗ | a+b three layers › Profilin-like › sensor domains › sensor domains › HrcA | 0.78 | 74.0 | 4.99e-01 | 100.0% | 33.3% |
| 3217110 | 3939.1.1.0 ↗ | alpha duplicates or obligate multimers › XRCC4 C-terminal oligomerization domain › XRCC4 C-terminal oligomerization domain › XRCC4 C-terminal oligomerization domain | 0.78 | 66.0 | 6.52e-01 | 98.8% | 84.7% |
| 3501227 | 192.22.1.0 ↗ | alpha bundles › Long alpha-hairpin › Ral binding domain of RLIP76 › Ral binding domain of RLIP76 | 0.76 | 61.0 | 6.57e-01 | 93.8% | 97.1% |
| 3988260 | 7516.1.1.2 ↗ | a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Glycos_transf_2 | 0.76 | 59.0 | 3.83e-01 | 100.0% | 20.3% |
| 4953123 | 2004.1.1.198 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_23 | 0.74 | 68.0 | 4.25e-01 | 100.0% | 26.2% |
| 3294774 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.74 | 71.0 | 4.90e-01 | 100.0% | 79.1% |
| 3258925 | 192.8.1.0 ↗ | alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain | 0.74 | 61.0 | 6.50e-01 | 96.2% | 100.0% |
| 4989041 | 7094.1.1.4 ↗ | alpha bundles › Paddle domain of mitochondrial dynamin › Paddle domain of mitochondrial dynamin › Paddle domain of mitochondrial dynamin › PF27273 | 0.74 | 61.0 | 6.40e-01 | 92.5% | 95.9% |
| 3848917 | 3939.1.1.0 ↗ | alpha duplicates or obligate multimers › XRCC4 C-terminal oligomerization domain › XRCC4 C-terminal oligomerization domain › XRCC4 C-terminal oligomerization domain | 0.74 | 59.0 | 5.84e-01 | 98.8% | 80.0% |
| 3960437 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.73 | 66.0 | 5.03e-01 | 96.2% | 48.2% |
| 4018104 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.73 | 68.0 | 4.47e-01 | 100.0% | 94.2% |
| 3764851 | 192.8.1.0 ↗ | alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain | 0.72 | 61.0 | 5.82e-01 | 100.0% | 78.9% |
| 3793248 | 174.1.1.1 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin | 0.72 | 63.0 | 4.83e-01 | 97.5% | 44.8% |
| 3473220 | 5086.1.1.209 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › LIN9_C | 0.72 | 69.0 | 5.94e-01 | 100.0% | 69.6% |
| 3635376 | 3755.3.1.298 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › ING | 0.72 | 67.0 | 5.49e-01 | 98.8% | 61.5% |
| 4471170 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.72 | 67.0 | 4.11e-01 | 98.8% | 55.7% |
| 4956384 | 3755.4.1.0 ↗ | alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain | 0.72 | 61.0 | 4.49e-01 | 100.0% | 37.4% |
| 4575178 | 606.1.1.0 ↗ | alpha complex topology › Nop N-terminal domain › Nop N-terminal domain › Nop N-terminal domain | 0.72 | 66.0 | 4.95e-01 | 100.0% | 44.3% |
| 3169125 | 4015.1.1.1 ↗ | alpha complex topology › alpha-helical domain in sec1/munc18-like (SM) proteins › alpha-helical domain in sec1/munc18-like (SM) proteins › alpha-helical domain in sec1/munc18-like (SM) proteins › Sec1 | 0.71 | 65.0 | 4.37e-01 | 100.0% | 47.0% |
| 3596479 | 3922.1.1.0 ↗ | alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 | 0.71 | 67.0 | 5.57e-01 | 100.0% | 61.5% |
| None | — | 0.71 | 67.0 | 5.56e-01 | 100.0% | 61.5% | |
| 3857357 | 192.2.1.0 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin | 0.71 | 67.0 | 5.94e-01 | 100.0% | 75.5% |
| 4956930 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.71 | 63.0 | 4.50e-01 | 100.0% | 41.7% |
| 3519972 | 192.5.1.14 ↗ | alpha bundles › Long alpha-hairpin › HR1 repeat › HR1 repeat › HR1_TOCA | 0.71 | 65.0 | 6.24e-01 | 97.5% | 94.4% |
| 3393869 | 604.6.1.2 ↗ | alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain › ANTH | 0.71 | 64.0 | 4.44e-01 | 95.0% | 33.8% |
| 4366813 | 192.7.1.2 ↗ | alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N | 0.70 | 66.0 | 5.86e-01 | 100.0% | 72.7% |
| 3692753 | 5086.1.1.12 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › Uds1 | 0.70 | 66.0 | 5.21e-01 | 100.0% | 67.3% |
| 3718482 | 603.2.1.0 ↗ | alpha bundles › STAT-like › STAT › STAT | 0.70 | 65.0 | 5.01e-01 | 100.0% | 57.3% |
| 3623411 | 192.2.1.0 ↗ | alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin | 0.70 | 65.0 | 6.07e-01 | 98.8% | 97.9% |
| 4108474 | 192.7.1.2 ↗ | alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N | 0.69 | 66.0 | 5.69e-01 | 100.0% | 69.6% |
| 4002563 | 192.8.1.303 ↗ | alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain › Tmemb_cc2 | 0.69 | 64.0 | 4.75e-01 | 97.5% | 43.3% |
| 5008445 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.69 | 58.0 | 6.00e-01 | 96.2% | 98.7% |
| 3717072 | 3567.1.1.0 ↗ | a+b duplicates or obligate multimers › MPER trimer › MPER trimer › MPER trimer | 0.69 | 61.0 | 4.89e-01 | 100.0% | 51.7% |
| 4279265 | 2004.1.1.481 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N, AAA_29 | 0.69 | 63.0 | 3.95e-01 | 98.8% | 22.1% |
| 3494198 | 328.7.1.0 ↗ | a+b two layers › IF3-like › Smr domain › Smr domain | 0.69 | 64.0 | 4.73e-01 | 100.0% | 42.1% |
| 3594138 | 604.32.1.0 ↗ | alpha bundles › Spectrin repeat-like › Recombination protein uvsY › Recombination protein uvsY | 0.69 | 62.0 | 5.33e-01 | 96.2% | 66.7% |
| 3923564 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.68 | 64.0 | 4.02e-01 | 100.0% | 21.9% |
| 4007316 | 3291.1.1.4 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › PspA_IM30 | 0.68 | 63.0 | 4.99e-01 | 100.0% | 81.9% |
| 3221283 | 604.5.1.0 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) | 0.68 | 63.0 | 5.09e-01 | 100.0% | 55.2% |
| 4015178 | 3755.4.1.0 ↗ | alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain | 0.68 | 63.0 | 4.95e-01 | 100.0% | 51.6% |
| 5004434 | 3558.1.1.0 ↗ | alpha arrays › HSDR subunit helical domain › HSDR subunit helical domain › HSDR subunit helical domain | 0.68 | 61.0 | 5.24e-01 | 97.5% | 64.2% |
| 3681007 | 604.1.1.3 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › MAP65_ASE1 | 0.68 | 58.0 | 5.36e-01 | 100.0% | 73.0% |
| 3602776 | 605.6.1.12 ↗ | alpha duplicates or obligate multimers › ROP-like › HP1531-like › HP1531-like › PF27273 | 0.68 | 57.0 | 5.72e-01 | 92.5% | 98.8% |
| 4402843 | 604.1.1.20 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › AKNA | 0.68 | 53.0 | 4.73e-01 | 98.8% | 59.1% |
| 5047074 | 2004.1.1.87 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N | 0.67 | 62.0 | 3.92e-01 | 100.0% | 26.5% |
| 3861615 | 150.1.1.190 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › SAP130_C | 0.67 | 58.0 | 5.37e-01 | 100.0% | 75.0% |
| 4572974 | 3922.1.1.79 ↗ | alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › SAP130_C | 0.67 | 58.0 | 5.09e-01 | 100.0% | 65.2% |
| 3960197 | 3291.1.1.4 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › PspA_IM30 | 0.66 | 61.0 | 4.34e-01 | 98.8% | 38.1% |
| 3650048 | 109.1.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › Glutathione S-transferase (GST)-C › Glutathione S-transferase (GST)-C | 0.66 | 57.0 | 4.07e-01 | 97.5% | 32.8% |
| 3239791 | 2004.1.1.0 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases | 0.65 | 60.0 | 4.53e-01 | 100.0% | 49.4% |
| 3697399 | 3755.3.1.0 ↗ | alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin | 0.64 | 59.0 | 4.60e-01 | 98.8% | 66.9% |
| 3598199 | 3755.1.1.0 ↗ | alpha bundles › YscO-like › Putative type III secretion protein YscO-related › Putative type III secretion protein YscO-related | 0.64 | 59.0 | 4.41e-01 | 100.0% | 64.9% |
| 4623646 | 2004.1.1.480 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N, AAA_21, AAA_29 | 0.64 | 59.0 | 3.69e-01 | 100.0% | 27.7% |
| 4046724 | 3922.1.1.0 ↗ | alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 | 0.64 | 59.0 | 4.68e-01 | 98.8% | 63.3% |
| 3698292 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.64 | 48.0 | 3.98e-01 | 100.0% | 44.8% |
| 5039563 | 604.5.1.0 ↗ | alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) | 0.64 | 54.0 | 4.12e-01 | 97.5% | 65.4% |
| 3926392 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.63 | 52.0 | 4.44e-01 | 93.8% | 100.0% |
| 3277932 | 150.5.1.52 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like › PE | 0.62 | 53.0 | 5.14e-01 | 100.0% | 83.3% |
| 3607135 | 5086.1.1.0 ↗ | alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins | 0.62 | 56.0 | 4.66e-01 | 100.0% | 59.3% |
| 3232800 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.61 | 51.0 | 3.46e-01 | 93.8% | 26.1% |
| 3564741 | 3860.1.1.322 ↗ | alpha bundles › Myosin VI lever arm › Myosin VI lever arm › Myosin VI lever arm › KELK | 0.61 | 54.0 | 3.47e-01 | 100.0% | 22.5% |
| 4868767 | 3559.1.1.1 ↗ | a+b complex topology › Mediator of RNA polymerase II transcription subunit 22 › Mediator of RNA polymerase II transcription subunit 22 › Mediator of RNA polymerase II transcription subunit 22 › Med22 | 0.60 | 54.0 | 4.56e-01 | 100.0% | 64.1% |
| 3441963 | 605.1.1.222 ↗ | alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › DUF4220 | 0.60 | 55.0 | 4.85e-01 | 100.0% | 85.2% |
| 3795092 | 622.4.1.0 ↗ | alpha bundles › YvfG-like › Mite allergen Der p 5-related › Mite allergen Der p 5-related | 0.60 | 53.0 | 4.47e-01 | 100.0% | 69.6% |
| 3291596 | 150.5.1.52 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › ESAT-6 like › ESAT-6 like › PE | 0.58 | 50.0 | 4.66e-01 | 100.0% | 75.0% |
| 3271624 | 2004.1.1.184 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_11 | 0.57 | 50.0 | 3.18e-01 | 100.0% | 24.4% |
| 3640760 | 3291.1.1.17 ↗ | alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › DUF202 | 0.56 | 49.0 | 4.36e-01 | 98.8% | 69.1% |
| 5028472 | 5058.1.1.16 ↗ | alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › MS_channel_1st_1 | 0.55 | 48.0 | 4.58e-01 | 100.0% | 82.2% |
| 3881907 | 2498.1.1.64 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M48_N | 0.53 | 45.0 | 3.21e-01 | 93.8% | 30.4% |
D2
medium
residues 88-148
Domain cluster:
representative
CATH (20)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2n00A00 | 1.10.533.10 | Mainly Alpha › Orthogonal Bundle › Death Domain, Fas › Death Domain, Fas | 0.76 | 67.0 | 5.77e-01 | 98.4% | 75.8% |
| 6ncvA00 | 1.10.533.10 | Mainly Alpha › Orthogonal Bundle › Death Domain, Fas › Death Domain, Fas | 0.74 | 63.0 | 5.58e-01 | 98.4% | 83.5% |
| 5dvwA00 | 1.20.120.1160 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.71 | 62.0 | 4.88e-01 | 100.0% | 65.2% |
| 1y8qC00 | 3.40.50.720 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain | 0.65 | 43.0 | 2.71e-01 | 72.1% | 13.2% |
| 1af7A01 | 1.10.155.10 | Mainly Alpha › Orthogonal Bundle › Chemotaxis Receptor Methyltransferase Cher; domain 1 › Chemotaxis receptor methyltransferase CheR, N-terminal domain | 0.62 | 47.0 | 4.42e-01 | 86.9% | 76.2% |
| 1tt5C01 | 3.40.50.720 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain | 0.59 | 42.0 | 2.66e-01 | 75.4% | 15.7% |
| 1vw4L02 | 1.10.246.170 | Mainly Alpha › Orthogonal Bundle › Serum Albumin; Chain A, Domain 1 › | 0.56 | 42.0 | 3.80e-01 | 80.3% | 95.3% |
| 3nbiA01 | 1.10.8.1020 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › RecQ-mediated genome instability protein 1, N-terminal domain | 0.56 | 42.0 | 4.36e-01 | 88.5% | 87.9% |
| 2cycA01 | 3.40.50.620 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HUPs | 0.54 | 46.0 | 3.15e-01 | 96.7% | 31.4% |
| 2knaA01 | 1.10.8.10 | Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Ubiquitin-associated (UBA) domain | 0.53 | 35.0 | 3.65e-01 | 82.0% | 75.9% |
| 3dtoA01 | 1.10.472.50 | Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › HD-domain/PDEase-like | 0.53 | 43.0 | 3.89e-01 | 98.4% | 64.8% |
| 2be4A02 | 1.10.238.10 | Mainly Alpha › Orthogonal Bundle › Recoverin; domain 1 › EF-hand | 0.53 | 42.0 | 3.59e-01 | 86.9% | 72.3% |
| 1td6A03 | 1.10.472.40 | Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Hypothetical protein mg237 homolog; domain 3 | 0.53 | 44.0 | 3.95e-01 | 100.0% | 66.3% |
| 4ga4A01 | 1.20.970.10 | Mainly Alpha › Up-down Bundle › Transferase, Pyrimidine Nucleoside Phosphorylase; Chain A, domain 3 › Transferase, Pyrimidine Nucleoside Phosphorylase; Chain C | 0.53 | 35.0 | 3.41e-01 | 70.5% | 61.2% |
| 6kjoA01 | 1.20.920.60 | Mainly Alpha › Up-down Bundle › Histone Acetyltransferase; Chain A › | 0.52 | 40.0 | 3.38e-01 | 91.8% | 73.4% |
| 3vkgA14 | 6.10.140.1060 | Special › Helix non-globular › Helix Hairpins › | 0.52 | 35.0 | 3.22e-01 | 73.8% | 53.8% |
| 2i7uA00 | 6.10.250.1010 | Special › Helix non-globular › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › | 0.51 | 37.0 | 3.74e-01 | 78.7% | 93.5% |
| 4o1pD02 | 1.10.510.10 | Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 | 0.51 | 41.0 | 2.79e-01 | 91.8% | 51.6% |
| 1d3yA01 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.51 | 38.0 | 3.60e-01 | 86.9% | 67.6% |
| 1l0oC00 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.50 | 35.0 | 3.63e-01 | 77.0% | 78.9% |
ECOD (19)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4505497 | 103.5.1.1 ↗ | alpha arrays › RuvA-C › post-HMGL domain-like › post-HMGL domain-like › PYC_OADA | 0.71 | 49.0 | 4.79e-01 | 100.0% | 66.2% |
| 3428698 | 706.1.1.3 ↗ | beta complex topology › Head domain of nucleotide exchange factor GrpE › Head domain of nucleotide exchange factor GrpE › Head domain of nucleotide exchange factor GrpE › GIL1_IRKI_C | 0.68 | 58.0 | 4.00e-01 | 100.0% | 57.4% |
| 3269226 | 101.1.10.0 ↗ | alpha arrays › HTH › HTH › Cyclin-like | 0.61 | 43.0 | 4.03e-01 | 96.7% | 61.3% |
| 3404906 | 4044.1.1.0 ↗ | alpha bundles › Helical bundle domain in prismane-like proteins › Helical bundle domain in prismane-like proteins › Helical bundle domain in prismane-like proteins | 0.60 | 51.0 | 4.45e-01 | 100.0% | 86.0% |
| 3403877 | 108.1.1.25 ↗ | alpha arrays › EF-hand › EF-hand-related › EF-hand › EF-hand_4 | 0.60 | 46.0 | 3.91e-01 | 83.6% | 75.0% |
| 4310452 | 108.1.1.25 ↗ | alpha arrays › EF-hand › EF-hand-related › EF-hand › EF-hand_4 | 0.59 | 45.0 | 3.71e-01 | 83.6% | 64.3% |
| None | — | 0.58 | 45.0 | 3.77e-01 | 85.2% | 66.4% | |
| 3877840 | 108.1.1.25 ↗ | alpha arrays › EF-hand › EF-hand-related › EF-hand › EF-hand_4 | 0.57 | 41.0 | 4.02e-01 | 95.1% | 70.0% |
| 3739208 | 148.1.3.0 ↗ | alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain | 0.57 | 45.0 | 4.48e-01 | 100.0% | 86.2% |
| 3596044 | 108.1.1.0 ↗ | alpha arrays › EF-hand › EF-hand-related › EF-hand | 0.56 | 47.0 | 3.90e-01 | 100.0% | 95.0% |
| 3545484 | 103.1.1.53 ↗ | alpha arrays › RuvA-C › RuvA-C, UBA, CRAL/TRIO-N, HBS1 › UBA-like domain › TTC3_9th | 0.56 | 42.0 | 4.21e-01 | 88.5% | 80.0% |
| 3531746 | 603.1.1.105 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › PF31021 | 0.56 | 39.0 | 3.29e-01 | 73.8% | 55.2% |
| 3865590 | 103.1.1.24 ↗ | alpha arrays › RuvA-C › RuvA-C, UBA, CRAL/TRIO-N, HBS1 › UBA-like domain › BIRC2-3-like_UBA | 0.56 | 38.0 | 3.79e-01 | 88.5% | 69.2% |
| 4973140 | 632.7.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain | 0.54 | 40.0 | 3.74e-01 | 88.5% | 64.0% |
| 3388607 | 603.1.1.105 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › PF31021 | 0.54 | 36.0 | 3.14e-01 | 80.3% | 43.0% |
| 3465537 | 7579.1.1.5 ↗ | a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases › Peptidase_S10 | 0.53 | 41.0 | 2.75e-01 | 98.4% | 20.0% |
| 3973232 | 7577.1.1.1 ↗ | a/b three-layered sandwiches › PLP-dependent transferases › PLP-dependent transferases › PLP-dependent transferases › Aminotran_1_2 | 0.53 | 42.0 | 2.89e-01 | 95.1% | 88.1% |
| 3330730 | 7579.1.1.5 ↗ | a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases › Peptidase_S10 | 0.51 | 41.0 | 2.82e-01 | 100.0% | 22.8% |
| 3684022 | 7579.1.1.5 ↗ | a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases › Peptidase_S10 | 0.51 | 42.0 | 2.59e-01 | 100.0% | 13.7% |