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IMGVR_UViG_2811995091_000018-2811995091-2813116557

Arc-Vir

IMGVR_UViG_2811995091_000018-2811995091-2813116557

Identity

Kingdom:
archaea

Quality

79.4 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 medium residues 21-88_219-294
PDB
Domain cluster: representative
CATH (78)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
8ek4A01 1.20.120.20 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein 0.88 68.0 7.14e-01 97.9% 86.5%
2efkA01 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.86 70.0 5.61e-01 84.7% 69.1%
3qweA00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.85 69.0 5.55e-01 84.7% 65.0%
4wpeA00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.84 63.0 4.98e-01 77.8% 72.4%
4oydB00 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.83 59.0 6.47e-01 95.8% 88.9%
1wp1B01 1.20.1600.10 Mainly Alpha › Up-down Bundle › Outer membrane efflux proteins (OEP) › Outer membrane efflux proteins (OEP) 0.82 59.0 4.21e-01 72.9% 77.7%
6xj1A01 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.81 65.0 5.37e-01 84.0% 73.9%
3g9gA00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.81 66.0 5.34e-01 84.0% 55.2%
1jadA00 1.20.1230.10 Mainly Alpha › Up-down Bundle › Phospholipase C Beta; Chain: A › Phospholipase C beta, distal C-terminal domain 0.81 59.0 4.85e-01 74.3% 69.0%
4m70I00 1.20.5.4130 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.81 39.0 4.48e-01 72.9% 62.0%
4dylA01 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.80 65.0 5.33e-01 84.7% 74.8%
4l8iB00 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.80 57.0 6.36e-01 98.6% 92.9%
1uruA01 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.80 65.0 5.70e-01 85.4% 73.7%
4mt4A00 1.20.1600.10 Mainly Alpha › Up-down Bundle › Outer membrane efflux proteins (OEP) › Outer membrane efflux proteins (OEP) 0.79 61.0 4.10e-01 79.2% 67.8%
3pltA00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.78 64.0 5.53e-01 85.4% 63.1%
2v0oB00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.78 58.0 4.58e-01 75.7% 69.0%
3s84A02 1.20.120.20 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein 0.77 55.0 5.38e-01 84.0% 66.9%
4nqiD00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.76 61.0 5.13e-01 83.3% 69.4%
2q12A00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.76 63.0 5.27e-01 87.5% 63.2%
6iknD01 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.76 60.0 4.80e-01 81.9% 65.2%
3hr0B01 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.75 42.0 5.58e-01 82.6% 100.0%
1t72A02 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.75 44.0 5.27e-01 95.1% 85.7%
1i4dA00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.74 58.0 5.27e-01 81.9% 65.4%
1sumB01 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.73 48.0 5.50e-01 100.0% 89.7%
2ficB00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.72 59.0 5.26e-01 86.8% 74.6%
7metA01 1.20.1560.10 Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain 0.72 64.0 4.98e-01 96.5% 45.6%
2hydA01 1.20.1560.10 Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain 0.72 64.0 4.89e-01 96.5% 43.7%
4mrsA01 1.20.1560.10 Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain 0.71 64.0 4.81e-01 97.2% 41.2%
2ch7A00 1.10.287.950 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Methyl-accepting chemotaxis protein 0.71 54.0 4.18e-01 79.2% 92.2%
7zo9A01 1.20.1560.10 Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain 0.70 63.0 4.82e-01 96.5% 45.0%
2d1lA00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.70 55.0 4.59e-01 83.3% 69.9%
3lssA01 1.10.287.40 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain 0.70 43.0 4.86e-01 88.9% 79.5%
1qu7A00 1.10.287.950 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Methyl-accepting chemotaxis protein 0.70 54.0 4.65e-01 81.2% 58.6%
5j1hA01 1.20.58.1060 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.69 54.0 4.95e-01 85.4% 63.7%
7zdtD01 1.20.1560.10 Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain 0.69 61.0 4.59e-01 93.1% 92.9%
3l1nA02 1.20.1280.140 Mainly Alpha › Up-down Bundle › Monooxygenase › 0.69 40.0 4.91e-01 96.5% 93.1%
4iggB02 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.69 38.0 4.09e-01 95.1% 62.0%
1owaA02 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.69 45.0 5.05e-01 97.9% 87.7%
7wivA01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.69 58.0 4.47e-01 91.0% 41.7%
3k29A00 1.10.287.1700 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.69 56.0 5.40e-01 84.7% 85.7%
3cazB00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.69 54.0 4.80e-01 84.0% 61.4%
6v9zA02 1.20.1560.10 Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain 0.69 60.0 4.59e-01 94.4% 42.8%
4q4hA01 1.20.1560.10 Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain 0.69 61.0 4.70e-01 96.5% 45.0%
1vi0A02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.68 40.0 4.05e-01 97.9% 57.2%
3vkhA11 1.20.920.20 Mainly Alpha › Up-down Bundle › Histone Acetyltransferase; Chain A › 0.68 51.0 3.94e-01 77.8% 100.0%
3syvA01 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.67 54.0 4.49e-01 84.0% 54.3%
3g67A00 1.10.287.950 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Methyl-accepting chemotaxis protein 0.67 52.0 4.59e-01 81.2% 56.3%
4mh6A00 1.10.287.1700 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.67 54.0 5.21e-01 84.0% 93.1%
3r84A00 1.10.287.3490 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.67 38.0 4.94e-01 84.7% 100.0%
3l8rA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.66 44.0 5.05e-01 100.0% 93.1%
1fewA00 1.20.58.70 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.66 55.0 5.18e-01 100.0% 73.4%
2dw4A03 1.10.287.80 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ATP synthase, gamma subunit, helix hairpin domain 0.66 45.0 5.35e-01 89.6% 100.0%
7sgrA02 1.20.1560.10 Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain 0.66 59.0 4.54e-01 97.2% 44.8%
3na7A00 1.10.287.1490 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.66 49.0 4.18e-01 78.5% 49.4%
2dq0A01 1.10.287.40 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain 0.66 41.0 4.72e-01 88.2% 85.0%
1wa8A00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.65 36.0 4.24e-01 83.3% 76.8%
3qo8A01 1.10.287.40 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain 0.65 39.0 4.47e-01 91.0% 80.2%
4q4hB01 1.20.1560.10 Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain 0.65 57.0 4.36e-01 96.5% 41.3%
6tqfA01 1.20.1560.10 Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain 0.65 56.0 4.11e-01 94.4% 41.4%
4cqiA00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.64 46.0 5.20e-01 98.6% 100.0%
1u5pA01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.64 42.0 4.77e-01 97.9% 88.9%
3ajmB02 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.64 42.0 4.38e-01 98.6% 72.2%
7p3rA01 1.20.1170.10 Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › 0.63 57.0 4.41e-01 99.3% 80.6%
1wleA01 1.10.287.40 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain 0.62 40.0 4.40e-01 94.4% 79.8%
1qsdA00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.62 43.0 4.96e-01 97.2% 100.0%
3h3mA00 1.20.58.380 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Flagellar protein flit. 0.62 29.0 3.68e-01 75.7% 73.0%
3uumA00 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.62 42.0 4.53e-01 97.9% 81.1%
4k7rA01 1.20.1600.10 Mainly Alpha › Up-down Bundle › Outer membrane efflux proteins (OEP) › Outer membrane efflux proteins (OEP) 0.61 56.0 4.18e-01 98.6% 55.0%
6q45G01 1.10.287.80 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ATP synthase, gamma subunit, helix hairpin domain 0.61 43.0 4.37e-01 72.9% 80.1%
1y1uA01 1.20.1050.20 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › STAT transcription factor, all-alpha domain 0.61 55.0 5.01e-01 100.0% 81.0%
7c1iA01 1.20.120.160 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain 0.60 34.0 4.00e-01 100.0% 79.0%
1bf5A01 1.20.1050.20 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › STAT transcription factor, all-alpha domain 0.58 49.0 4.67e-01 100.0% 77.4%
2b0hA01 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.58 42.0 4.46e-01 100.0% 84.4%
2rd0B00 1.10.287.1490 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.57 46.0 4.68e-01 84.0% 87.1%
2y44A00 1.20.1260.80 Mainly Alpha › Up-down Bundle › Ferritin › 0.57 46.0 4.28e-01 90.3% 67.4%
3ofnY00 1.10.287.80 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ATP synthase, gamma subunit, helix hairpin domain 0.57 41.0 4.55e-01 78.5% 93.0%
3gi7A00 1.20.1270.180 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.56 34.0 3.85e-01 91.7% 82.5%
4yjwA00 1.20.120.930 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Uncharacterised protein PF12889, N-terminal DUF3829 0.54 43.0 4.25e-01 84.7% 100.0%
ECOD (92)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3402327 3755.3.1.324 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › DUF725 0.89 72.0 6.75e-01 83.3% 85.3%
3213527 4177.1.1.1 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FCH 0.86 70.0 5.46e-01 84.7% 58.2%
3519973 4177.1.1.0 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like 0.86 71.0 5.77e-01 85.4% 84.9%
3488631 4177.1.1.0 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like 0.85 69.0 5.43e-01 84.0% 57.8%
3213281 4177.1.1.1 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FCH 0.83 67.0 5.34e-01 84.7% 70.0%
3881581 310.2.1.11 a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF › DUF4456 0.79 69.0 6.60e-01 97.2% 80.6%
4259224 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.79 62.0 6.04e-01 81.9% 84.5%
3667580 4177.1.1.0 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like 0.78 72.0 5.76e-01 98.6% 66.8%
3559586 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.78 57.0 5.65e-01 84.7% 72.7%
4980098 3834.1.1.0 alpha bundles › TcA alpha pore-forming domain › TcA alpha pore-forming domain › TcA alpha pore-forming domain 0.75 60.0 4.84e-01 84.0% 81.1%
5007124 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.74 56.0 4.36e-01 78.5% 46.9%
5019536 3755.1.1.0 alpha bundles › YscO-like › Putative type III secretion protein YscO-related › Putative type III secretion protein YscO-related 0.73 67.0 5.67e-01 100.0% 62.2%
4569106 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.73 51.0 3.47e-01 70.8% 100.0%
3505596 1075.4.1.9 alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › ABC_tran+ABC_membrane 0.73 65.0 4.62e-01 96.5% 33.3%
4030425 1075.4.1.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › ABC_membrane 0.73 66.0 4.88e-01 97.2% 40.6%
4371230 2004.1.1.615 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N, AAA_21, AAA_23, AAA_29 0.72 64.0 4.03e-01 95.8% 63.8%
3908810 4177.1.1.1 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FCH 0.72 58.0 4.54e-01 84.7% 44.4%
3967398 3755.1.1.1 alpha bundles › YscO-like › Putative type III secretion protein YscO-related › Putative type III secretion protein YscO-related › YscO 0.72 52.0 5.16e-01 74.3% 90.0%
3702347 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.72 56.0 5.27e-01 81.9% 92.0%
3952630 3755.1.1.0 alpha bundles › YscO-like › Putative type III secretion protein YscO-related › Putative type III secretion protein YscO-related 0.72 54.0 5.48e-01 77.1% 88.6%
3994267 1075.4.1.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › ABC_membrane 0.71 64.0 4.84e-01 96.5% 42.1%
3970271 3755.1.1.8 alpha bundles › YscO-like › Putative type III secretion protein YscO-related › Putative type III secretion protein YscO-related › FliJ 0.71 51.0 5.42e-01 73.6% 95.2%
3712647 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.71 58.0 4.46e-01 86.8% 44.7%
4543045 1075.4.1.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › ABC_membrane 0.70 63.0 4.92e-01 96.5% 46.7%
3718629 3755.2.1.0 alpha bundles › YscO-like › Flagellar FliJ protein › Flagellar FliJ protein 0.70 56.0 4.52e-01 82.6% 62.3%
3178828 1075.4.1.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › ABC_membrane 0.70 64.0 4.83e-01 97.2% 43.4%
3964627 1075.4.1.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › ABC_membrane 0.70 64.0 4.84e-01 100.0% 42.6%
3366371 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.70 56.0 4.52e-01 84.7% 50.0%
3989648 1203.1.2.17 alpha bundles › Shroom domain 2 › Shroom domain 2 › Human SD2 › ABC_membrane 0.70 61.0 5.51e-01 97.2% 69.0%
4036645 5086.1.1.92 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_AprE 0.69 55.0 4.99e-01 84.0% 84.6%
3968294 1075.4.1.0 alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold 0.69 62.0 4.92e-01 97.2% 49.5%
3417771 1075.4.1.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › ABC_membrane 0.69 61.0 5.27e-01 96.5% 64.0%
2321604 1075.4.1.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › ABC_membrane 0.69 61.0 4.71e-01 96.5% 45.1%
3182561 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.69 54.0 5.16e-01 82.6% 77.6%
5053334 1075.4.1.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › ABC_membrane 0.68 60.0 4.58e-01 93.8% 93.1%
4966374 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.68 52.0 4.85e-01 95.1% 64.6%
3577907 4177.1.1.0 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like 0.68 54.0 4.48e-01 84.0% 68.2%
3579748 3755.4.1.0 alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain 0.68 51.0 4.80e-01 77.1% 71.2%
4016292 192.2.1.18 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › ING 0.68 54.0 5.57e-01 83.3% 91.9%
4943964 3922.1.1.355 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › ABC_membrane 0.68 61.0 4.61e-01 96.5% 42.7%
3808040 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.67 62.0 5.70e-01 100.0% 87.4%
3587375 1075.4.1.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › ABC_membrane 0.67 62.0 4.77e-01 99.3% 46.1%
5060432 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.67 48.0 5.09e-01 74.3% 92.3%
4978121 1075.4.1.0 alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold 0.67 61.0 4.69e-01 99.3% 44.6%
3341646 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.67 57.0 4.45e-01 89.6% 86.6%
4206235 3755.4.1.0 alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain 0.67 48.0 3.97e-01 73.6% 94.5%
4219808 192.1.1.0 alpha bundles › Long alpha-hairpin › GreA transcript cleavage protein, N-terminal domain › GreA transcript cleavage protein, N-terminal domain 0.66 51.0 3.85e-01 81.2% 38.0%
3574611 2004.1.1.198 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_23 0.66 57.0 4.04e-01 93.8% 33.2%
3410076 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.66 51.0 4.02e-01 92.4% 40.3%
4392204 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.66 52.0 4.45e-01 81.9% 85.9%
3279225 1075.4.1.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › ABC_membrane 0.65 60.0 4.56e-01 99.3% 93.8%
3662731 1075.4.1.0 alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold 0.65 59.0 5.03e-01 100.0% 84.7%
3520603 2004.1.1.87 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N 0.65 52.0 3.39e-01 84.7% 62.2%
4234516 1075.4.1.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › ABC_membrane 0.65 57.0 4.33e-01 97.2% 42.9%
4549103 3755.4.1.54 alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › PF30340 0.64 55.0 4.00e-01 91.0% 100.0%
3580491 174.1.1.1 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin 0.64 54.0 5.21e-01 88.2% 96.2%
4028552 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.64 49.0 4.05e-01 94.4% 46.5%
5026838 4177.1.1.0 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like 0.64 57.0 4.83e-01 100.0% 62.9%
3920552 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.63 50.0 4.34e-01 92.4% 55.7%
3448339 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.63 42.0 4.25e-01 96.5% 66.2%
3958574 3291.1.1.0 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related 0.63 43.0 4.10e-01 83.3% 60.6%
4144790 3755.3.1.592 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › PF30340 0.62 55.0 4.03e-01 97.2% 95.2%
5047075 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.62 50.0 3.84e-01 85.4% 56.2%
4955963 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.62 50.0 4.48e-01 84.7% 67.0%
3522868 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.62 45.0 4.95e-01 95.1% 92.2%
4410114 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.62 45.0 3.76e-01 75.0% 100.0%
5010596 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.62 49.0 4.32e-01 84.7% 95.0%
4468389 5086.1.1.101 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › SH3BP5 0.62 46.0 5.02e-01 91.7% 93.3%
3730423 3922.1.1.0 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 0.62 51.0 3.91e-01 87.5% 85.0%
5007101 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.62 54.0 4.06e-01 95.8% 100.0%
3727084 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.61 49.0 3.90e-01 84.0% 95.4%
3691415 2004.1.1.748 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_15, AAA_23, SbcC_Walker_B 0.61 53.0 3.66e-01 96.5% 47.2%
3165834 3291.1.1.0 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related 0.61 45.0 3.74e-01 77.1% 100.0%
3694833 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.61 45.0 4.71e-01 79.2% 83.8%
4395939 192.2.1.0 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin 0.60 46.0 3.81e-01 79.2% 92.2%
3190705 2004.1.1.433 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N, AAA_23 0.60 51.0 3.42e-01 92.4% 53.6%
3880166 192.2.1.14 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › CDK5RAP3 0.60 51.0 4.39e-01 91.7% 94.8%
4028291 2004.1.1.87 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N 0.60 52.0 3.78e-01 95.8% 35.4%
4969098 3926.1.1.0 alpha bundles › V-type proton ATPase subunit D › V-type proton ATPase subunit D › V-type proton ATPase subunit D 0.59 48.0 4.51e-01 85.4% 98.3%
4975739 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.59 49.0 3.65e-01 89.6% 37.4%
4320633 2004.1.1.433 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N, AAA_23 0.59 51.0 3.52e-01 91.0% 76.9%
3862009 3755.3.1.293 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › TBCA_PH 0.59 53.0 5.18e-01 100.0% 91.3%
5068463 3758.1.1.0 alpha bundles › Bacterial hemolysins-like › Bacterial hemolysins › Bacterial hemolysins 0.58 54.0 4.93e-01 100.0% 89.2%
3182497 2004.1.1.87 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N 0.58 50.0 3.59e-01 93.8% 39.3%
3251434 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.58 51.0 4.75e-01 95.8% 95.0%
3697385 2004.1.1.87 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N 0.58 48.0 3.52e-01 91.7% 34.0%
4018888 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.57 52.0 3.80e-01 100.0% 76.7%
3571433 3939.1.1.220 alpha duplicates or obligate multimers › XRCC4 C-terminal oligomerization domain › XRCC4 C-terminal oligomerization domain › XRCC4 C-terminal oligomerization domain › KIF21A 0.56 49.0 4.72e-01 94.4% 85.0%
3275656 174.1.1.1 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin 0.54 44.0 4.39e-01 86.8% 99.3%
3625262 174.1.1.1 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin 0.53 46.0 4.39e-01 93.8% 95.9%
3626951 174.1.1.1 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin 0.53 43.0 4.29e-01 86.8% 99.3%
3628600 174.1.1.1 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin 0.50 40.0 3.99e-01 84.0% 94.7%
D2 medium residues 89-218
PDB
Domain cluster: representative
CATH (53)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4a17U01 1.10.287.310 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.89 46.0 5.99e-01 70.8% 87.0%
1yxrA01 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.79 42.0 5.61e-01 70.0% 93.2%
1fpoC02 1.20.1280.20 Mainly Alpha › Up-down Bundle › Monooxygenase › HscB, C-terminal domain 0.77 53.0 6.22e-01 85.4% 100.0%
1nafA02 1.20.58.160 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.75 44.0 5.41e-01 70.0% 90.6%
3fnbA01 1.20.1440.110 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › acylaminoacyl peptidase 0.74 44.0 4.69e-01 75.4% 66.7%
3nzpB03 1.20.58.930 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.72 43.0 5.42e-01 99.2% 98.7%
7csoA01 1.20.900.10 Mainly Alpha › Up-down Bundle › Dbl Homology Domain; Chain A › Dbl homology (DH) domain 0.72 49.0 4.09e-01 70.0% 83.6%
2vzbB00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.71 49.0 4.48e-01 70.8% 82.6%
1jgcA00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.70 50.0 4.60e-01 72.3% 80.0%
4yonA01 1.20.900.10 Mainly Alpha › Up-down Bundle › Dbl Homology Domain; Chain A › Dbl homology (DH) domain 0.70 48.0 4.03e-01 70.0% 88.0%
8fbnB01 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.69 48.0 3.90e-01 70.0% 43.2%
3mq1A01 1.20.58.970 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.69 46.0 5.47e-01 70.8% 96.7%
1s3qG00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.69 49.0 4.52e-01 73.1% 80.4%
3hiuD00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.69 49.0 4.61e-01 72.3% 85.5%
2fzfA01 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.68 48.0 4.53e-01 70.8% 90.0%
3fseB02 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.68 49.0 4.69e-01 73.1% 91.0%
3n2oA03 1.20.58.930 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.68 42.0 4.86e-01 98.5% 84.4%
2lm9A00 1.20.58.970 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.68 48.0 5.55e-01 76.2% 99.0%
3qhbA00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.68 48.0 4.30e-01 73.1% 81.6%
4etrB00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.68 47.0 4.91e-01 71.5% 88.5%
2rbdA01 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.68 47.0 4.49e-01 71.5% 88.7%
1uurA01 1.20.58.240 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › STAT; domain 1 0.66 48.0 5.22e-01 75.4% 93.6%
4cybD00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.65 47.0 4.22e-01 73.1% 80.7%
2p0nA00 1.20.120.520 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › nmb1532 protein domain like 0.65 45.0 4.18e-01 70.8% 91.9%
1k90B03 1.20.140.60 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › 0.64 42.0 4.43e-01 73.1% 73.9%
4nt1A00 1.10.3520.10 Mainly Alpha › Orthogonal Bundle › Glycolipid transfer protein, GLTP › Glycolipid transfer protein 0.63 47.0 4.06e-01 76.2% 94.0%
1vctA01 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.63 44.0 4.79e-01 75.4% 85.3%
2g2dA00 1.20.1200.10 Mainly Alpha › Up-down Bundle › Hypothetical Protein Ta1238; Chain: A; › Cobalamin adenosyltransferase-like 0.63 44.0 4.14e-01 72.3% 90.0%
5jrcA00 1.20.58.2140 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.62 47.0 4.13e-01 77.7% 58.1%
1b5lA00 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.62 43.0 4.09e-01 73.8% 60.5%
1bf5A01 1.20.1050.20 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › STAT transcription factor, all-alpha domain 0.62 45.0 4.15e-01 75.4% 64.3%
2fji101 1.10.357.50 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › 0.62 44.0 3.77e-01 73.1% 84.2%
1u89A00 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.62 45.0 4.45e-01 76.2% 76.3%
3lbxB01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.61 43.0 4.71e-01 75.4% 87.9%
2ntxA01 1.20.58.2010 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › PRONE domain, subdomain 1 0.61 49.0 4.14e-01 83.8% 81.4%
2qqyA00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.61 43.0 4.20e-01 70.0% 92.0%
3d19B00 1.20.1260.120 Mainly Alpha › Up-down Bundle › Ferritin › Protein of unknown function DUF2935 0.60 55.0 4.31e-01 98.5% 96.6%
4nwpD00 1.20.1200.10 Mainly Alpha › Up-down Bundle › Hypothetical Protein Ta1238; Chain: A; › Cobalamin adenosyltransferase-like 0.59 42.0 4.03e-01 72.3% 90.6%
7p3rA01 1.20.1170.10 Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › 0.59 45.0 3.32e-01 78.5% 90.8%
1wvtA00 1.20.1200.10 Mainly Alpha › Up-down Bundle › Hypothetical Protein Ta1238; Chain: A; › Cobalamin adenosyltransferase-like 0.59 41.0 3.99e-01 72.3% 90.5%
2r6tB01 1.20.1200.10 Mainly Alpha › Up-down Bundle › Hypothetical Protein Ta1238; Chain: A; › Cobalamin adenosyltransferase-like 0.59 41.0 3.84e-01 72.3% 85.5%
1rx0A03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.58 41.0 3.89e-01 73.1% 83.2%
5cy5B00 1.20.1200.10 Mainly Alpha › Up-down Bundle › Hypothetical Protein Ta1238; Chain: A; › Cobalamin adenosyltransferase-like 0.58 40.0 3.88e-01 71.5% 91.3%
4in3B00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.58 47.0 3.01e-01 86.2% 77.1%
5wp3B00 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.57 41.0 4.57e-01 78.5% 95.1%
2yfaA02 1.20.1440.210 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 0.56 45.0 4.77e-01 96.9% 95.7%
4dwlA00 1.20.1440.60 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 23S rRNA-intervening sequence 0.56 41.0 4.42e-01 76.2% 94.4%
1yo7A00 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.56 46.0 4.78e-01 100.0% 95.0%
1s2xA00 1.20.190.30 Mainly Alpha › Up-down Bundle › Delta-Endotoxin; domain 1 › CAG pathogenicity island protein, CagZ 0.55 41.0 3.72e-01 78.5% 63.9%
1foeA01 1.20.900.10 Mainly Alpha › Up-down Bundle › Dbl Homology Domain; Chain A › Dbl homology (DH) domain 0.55 40.0 3.50e-01 76.2% 80.5%
4gouA03 1.20.900.10 Mainly Alpha › Up-down Bundle › Dbl Homology Domain; Chain A › Dbl homology (DH) domain 0.53 46.0 3.99e-01 92.3% 75.1%
2fefA01 1.20.1440.70 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › PA2201 N-terminal domain-like 0.52 45.0 4.60e-01 100.0% 97.6%
1f6fA00 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.51 46.0 4.12e-01 99.2% 79.2%
ECOD (64)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3874130 133.1.1.5 alpha bundles › DH domain-like › DBL homology domain (DH-domain) › DBL homology domain (DH-domain) › DH_Alsin 0.75 53.0 4.48e-01 72.3% 96.7%
1177227 133.1.1.1 alpha bundles › DH domain-like › DBL homology domain (DH-domain) › DBL homology domain (DH-domain) › RhoGEF 0.75 52.0 4.10e-01 70.0% 75.9%
4019884 133.1.1.1 alpha bundles › DH domain-like › DBL homology domain (DH-domain) › DBL homology domain (DH-domain) › RhoGEF 0.75 52.0 4.16e-01 70.0% 79.6%
5046472 604.3.1.0 alpha bundles › Spectrin repeat-like › BAG domain › BAG domain 0.74 47.0 5.41e-01 73.1% 87.4%
3941051 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.72 50.0 4.57e-01 71.5% 63.5%
4026662 4207.1.2.0 alpha duplicates or obligate multimers › Mediator hinge subcomplex-like › Mediator hinge subcomplex-like › MED7 hinge region 0.71 45.0 4.46e-01 76.2% 60.0%
3886331 133.1.1.1 alpha bundles › DH domain-like › DBL homology domain (DH-domain) › DBL homology domain (DH-domain) › RhoGEF 0.71 49.0 3.96e-01 70.0% 79.6%
3512539 133.1.1.1 alpha bundles › DH domain-like › DBL homology domain (DH-domain) › DBL homology domain (DH-domain) › RhoGEF 0.71 49.0 4.09e-01 70.0% 87.4%
3248196 133.1.1.1 alpha bundles › DH domain-like › DBL homology domain (DH-domain) › DBL homology domain (DH-domain) › RhoGEF 0.71 48.0 4.11e-01 70.0% 85.7%
3260973 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.70 48.0 5.24e-01 72.3% 82.7%
5062016 604.5.1.0 alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) 0.70 49.0 5.50e-01 75.4% 93.0%
3271067 133.1.1.1 alpha bundles › DH domain-like › DBL homology domain (DH-domain) › DBL homology domain (DH-domain) › RhoGEF 0.69 48.0 4.01e-01 70.0% 85.6%
3300554 109.4.1.235 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › SRP68 0.69 50.0 3.31e-01 77.7% 19.6%
3794795 603.1.1.3 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › V-SNARE 0.69 48.0 5.42e-01 75.4% 92.0%
4958744 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.68 47.0 5.08e-01 72.3% 82.7%
4074827 603.1.1.97 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Syntaxin, SNARE 0.68 50.0 3.85e-01 75.4% 40.4%
3530780 310.2.1.2 a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF › MIX23 0.68 47.0 4.72e-01 70.0% 91.5%
3242496 133.1.1.1 alpha bundles › DH domain-like › DBL homology domain (DH-domain) › DBL homology domain (DH-domain) › RhoGEF 0.68 48.0 3.92e-01 72.3% 84.3%
3248840 150.1.1.8 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › DUF2383 0.67 46.0 4.42e-01 70.0% 86.0%
3400366 174.1.1.1 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin 0.67 50.0 4.87e-01 76.9% 87.1%
3259226 3758.1.1.0 alpha bundles › Bacterial hemolysins-like › Bacterial hemolysins › Bacterial hemolysins 0.67 52.0 4.40e-01 80.0% 76.9%
3513855 633.23.1.22 alpha bundles › Bromodomain-like › Claudin › Claudin › MARVEL 0.66 50.0 4.86e-01 77.7% 83.4%
3615269 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.66 49.0 4.09e-01 76.2% 65.7%
3501934 626.1.1.1 alpha complex topology › Formin homology 2 domain (FH2 domain) › Formin homology 2 domain (FH2 domain) › Formin homology 2 domain (FH2 domain) › FH2 0.66 47.0 3.33e-01 73.1% 48.1%
3220199 174.1.1.1 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin 0.65 48.0 4.47e-01 74.6% 88.4%
4018653 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.65 48.0 4.53e-01 74.6% 74.0%
4026054 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.65 46.0 4.26e-01 71.5% 80.4%
4958743 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.65 45.0 4.76e-01 72.3% 80.0%
3998192 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.64 46.0 2.73e-01 73.8% 19.0%
4962299 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.64 47.0 4.44e-01 76.2% 71.0%
3266050 5001.1.1.81 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › THH1_TOM1-3_dom 0.64 46.0 3.58e-01 73.8% 70.8%
3397047 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.64 46.0 4.75e-01 75.4% 86.4%
3690382 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.63 46.0 4.42e-01 75.4% 79.3%
3733397 109.42.1.0 alpha superhelices › Repetitive alpha hairpins › E3 ubiquitin-protein ligase SHPRH first helical domain › E3 ubiquitin-protein ligase SHPRH first helical domain 0.62 46.0 4.02e-01 76.2% 53.7%
3216756 109.4.1.3210 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Vps54, Vps54_N 0.62 50.0 3.25e-01 86.9% 17.9%
4863092 150.3.1.28 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › 4-helical cytokines › 4-helical cytokine › GCSF 0.61 50.0 5.38e-01 96.9% 98.2%
3712159 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.61 46.0 4.31e-01 77.7% 72.9%
3559937 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.60 43.0 4.75e-01 75.4% 92.4%
3991672 109.4.1.1373 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Syndetin_C, Vps54_N 0.60 47.0 3.01e-01 83.8% 26.4%
3773859 604.1.1.1 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin 0.60 43.0 4.68e-01 75.4% 91.4%
5001558 604.5.1.2 alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU 0.59 47.0 4.16e-01 100.0% 56.9%
3478235 633.23.1.0 alpha bundles › Bromodomain-like › Claudin › Claudin 0.58 51.0 5.17e-01 97.7% 94.5%
3276237 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.57 52.0 4.85e-01 100.0% 80.6%
3276862 3758.1.1.0 alpha bundles › Bacterial hemolysins-like › Bacterial hemolysins › Bacterial hemolysins 0.56 52.0 4.36e-01 100.0% 74.4%
4021431 174.1.1.0 few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain 0.56 51.0 5.01e-01 100.0% 90.0%
3234447 5001.1.1.34 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Srb 0.56 53.0 3.90e-01 100.0% 68.1%
3471983 633.23.1.0 alpha bundles › Bromodomain-like › Claudin › Claudin 0.56 45.0 4.38e-01 83.8% 92.1%
3682306 633.23.1.32 alpha bundles › Bromodomain-like › Claudin › Claudin › CASP_dom 0.56 52.0 4.75e-01 98.5% 99.4%
3416161 133.1.1.1 alpha bundles › DH domain-like › DBL homology domain (DH-domain) › DBL homology domain (DH-domain) › RhoGEF 0.56 44.0 3.76e-01 83.1% 64.4%
3228068 5001.1.1.45 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Sra 0.56 52.0 3.81e-01 100.0% 64.5%
3477817 133.1.1.1 alpha bundles › DH domain-like › DBL homology domain (DH-domain) › DBL homology domain (DH-domain) › RhoGEF 0.56 47.0 3.77e-01 90.0% 95.9%
3572169 633.23.1.22 alpha bundles › Bromodomain-like › Claudin › Claudin › MARVEL 0.55 49.0 4.92e-01 100.0% 94.6%
3875003 133.1.1.1 alpha bundles › DH domain-like › DBL homology domain (DH-domain) › DBL homology domain (DH-domain) › RhoGEF 0.55 45.0 3.80e-01 87.7% 85.9%
3436346 604.5.1.32 alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › TMEM120A-B 0.55 50.0 4.01e-01 99.2% 60.4%
3731259 5042.1.1.1 extended segments › Magnesium transport protein CorA, transmembrane region › Magnesium transport protein CorA, transmembrane region › Magnesium transport protein CorA, transmembrane region › CorA 0.55 36.0 3.22e-01 86.9% 48.6%
3217573 5001.1.1.45 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Sra 0.54 49.0 3.68e-01 100.0% 66.8%
3565220 633.23.1.22 alpha bundles › Bromodomain-like › Claudin › Claudin › MARVEL 0.54 50.0 4.87e-01 100.0% 91.0%
3735343 1075.5.1.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MatE 0.53 48.0 3.97e-01 100.0% 84.7%
4019304 633.21.1.0 alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 0.53 49.0 4.16e-01 100.0% 71.7%
3949475 5067.1.1.0 alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain 0.52 47.0 4.05e-01 100.0% 85.7%
3967617 604.5.1.0 alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) 0.52 46.0 4.29e-01 96.9% 84.2%
3918141 633.23.1.0 alpha bundles › Bromodomain-like › Claudin › Claudin 0.51 44.0 4.47e-01 100.0% 94.6%
3731804 5058.1.1.37 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › PF25886 0.51 37.0 3.55e-01 73.8% 75.2%
3996 150.3.1.1 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › 4-helical cytokines › 4-helical cytokine › Hormone_1 0.51 46.0 4.12e-01 99.2% 79.2%
D3 medium residues 295-472
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF10145.15 best PhageMin_Tail 73.9 2.40e-20 82.6% 69.7%
D4 medium residues 473-525
PDB
Domain cluster: representative
CATH (5)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3aayA02 3.40.250.10 Alpha Beta › 3-Layer(aba) Sandwich › Oxidized Rhodanese; domain 1 › Rhodanese-like domain 0.63 52.0 3.88e-01 90.6% 69.5%
2wlrA03 3.40.250.10 Alpha Beta › 3-Layer(aba) Sandwich › Oxidized Rhodanese; domain 1 › Rhodanese-like domain 0.57 45.0 3.32e-01 88.7% 65.5%
3bbyA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.54 35.0 2.84e-01 96.2% 30.8%
2e8eA00 3.30.300.20 Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › K homology (KH) domain 0.54 41.0 3.14e-01 84.9% 65.2%
2ziuA02 1.10.150.670 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Crossover junction endonuclease EME1, DNA-binding domain 0.53 37.0 3.24e-01 73.6% 68.7%
ECOD (8)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4030882 159.1.2.6 alpha bundles › all-alpha NTP pyrophosphatases › all-alpha NTP pyrophosphatases › MazG-related › PhageMin_Tail 0.77 69.0 4.54e-01 100.0% 26.7%
3945172 3826.1.1.0 alpha bundles › Copper-sensitive operon repressor (CsoR) › Copper-sensitive operon repressor (CsoR) › Copper-sensitive operon repressor (CsoR) 0.67 59.0 3.92e-01 98.1% 25.7%
3468055 601.7.1.0 alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain 0.59 50.0 3.94e-01 100.0% 53.3%
3724092 2003.1.1.148 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › adh_short, KR 0.55 45.0 2.78e-01 88.7% 32.5%
5048211 7584.1.1.0 a/b three-layered sandwiches › Rossmann-like domain in Acetyl-CoA synthetase-like proteins › Rossmann-like domain in Acetyl-CoA synthetase-like proteins › Rossmann-like domain in Acetyl-CoA synthetase-like proteins 0.55 47.0 2.84e-01 100.0% 25.9%
3736172 2484.1.1.4 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › RNase_H 0.54 43.0 3.01e-01 90.6% 62.1%
3193637 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.51 40.0 2.23e-01 94.3% 19.3%
4936947 5104.1.1.0 a+b three layers › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases › C-terminal domain in DHH phosphoesterases 0.50 39.0 3.02e-01 88.7% 39.2%