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IMGVR_UViG_2811995110_000069-2811995110-2813156823

Arc-Vir

IMGVR_UViG_2811995110_000069-2811995110-2813156823

Identity

Kingdom:
archaea

Quality

78.9 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

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Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 107-238
PDB
Domain cluster: representative
CATH (4)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2f4qA01 3.30.66.10 Alpha Beta › 2-Layer Sandwich › Viral Topoisomerase I › DNA topoisomerase I domain 0.75 34.0 4.51e-01 100.0% 79.2%
3itwA02 3.30.720.110 Alpha Beta › 2-Layer Sandwich › Signal recognition particle alu RNA binding heterodimer, srp9/1 › 0.60 24.0 3.48e-01 71.2% 83.9%
2oap202 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.55 38.0 3.05e-01 72.7% 73.3%
3gqhA02 4.10.80.40 Few Secondary Structures › Irregular › Rhinovirus 14, subunit 4 › succinate dehydrogenase protein domain 0.55 19.0 3.02e-01 92.4% 90.0%
ECOD (3)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3513421 391.1.1.7 ↗ few secondary structure elements › Fibronectin type I module-like › Fibronectin type I module-like › Fibronectin type I module › Fn1_2 0.52 27.0 3.72e-01 88.6% 100.0%
4015757 4.1.1.0 ↗ beta barrels › SH3 › SH3 › SH3 0.51 35.0 3.02e-01 91.7% 43.3%
3629049 391.1.1.7 ↗ few secondary structure elements › Fibronectin type I module-like › Fibronectin type I module-like › Fibronectin type I module › Fn1_2 0.50 26.0 3.07e-01 87.9% 69.5%
D2 high residues 468-585
PDB
Domain cluster: representative
CATH (21)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
7e5aB02 1.20.1000.10 Mainly Alpha › Up-down Bundle › Signaling Protein - Interferon-induced Guanylate-binding Protein 1; Chain A, domain 1 › Guanylate-binding protein, C-terminal domain 0.64 45.0 4.08e-01 94.9% 53.0%
1a41A02 1.20.120.380 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Type 1-topoisomerase catalytic fragment, domain 2 0.62 39.0 4.27e-01 89.0% 78.7%
2wdqC00 1.20.1300.10 Mainly Alpha › Up-down Bundle › 3 helical TM bundles of succinate and fumarate reductases › Fumarate reductase/succinate dehydrogenase, transmembrane subunit 0.60 42.0 4.23e-01 72.9% 73.6%
2vwaA00 1.20.58.1330 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Plasmodium falciparum UIS3 membrane protein 0.59 42.0 4.47e-01 98.3% 86.9%
1ku2A02 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.59 29.0 4.04e-01 85.6% 98.2%
4dveA00 1.10.1760.20 Mainly Alpha › Orthogonal Bundle › Arp2/3 complex 21 kDa subunit ARPC3 › 0.59 52.0 4.49e-01 98.3% 83.1%
1b8bA00 3.20.70.20 Alpha Beta › Alpha-Beta Barrel › Anaerobic Ribonucleotide-triphosphate Reductase Large Chain › 0.57 43.0 2.77e-01 78.0% 28.1%
3fhnA02 1.20.58.1420 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Dsl1p vesicle tethering complex, Tip20p subunit, domain B 0.57 38.0 3.85e-01 82.2% 68.4%
6humG01 1.20.120.1200 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › NADH-ubiquinone/plastoquinone oxidoreductase chain 6, subunit NuoJ 0.56 33.0 2.97e-01 83.9% 40.6%
1l0oC00 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.56 28.0 3.75e-01 89.0% 96.5%
2aj6A00 3.40.630.30 Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Gcn5-related N-acetyltransferase (GNAT) 0.55 29.0 2.89e-01 89.8% 45.8%
3fhnA03 1.10.357.100 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Dsl1p vesicle tethering complex, Tip20p subunit, domain C 0.54 42.0 3.79e-01 100.0% 56.9%
8b70A01 1.20.1740.10 Mainly Alpha › Up-down Bundle › Amino acid/polyamine transporter I › Amino acid/polyamine transporter I 0.54 45.0 3.17e-01 94.1% 63.9%
3u9rB02 3.90.226.10 Alpha Beta › Alpha-Beta Complex › 2-enoyl-CoA Hydratase; Chain A, domain 1 › 2-enoyl-CoA Hydratase; Chain A, domain 1 0.53 38.0 2.94e-01 77.1% 32.3%
3lynB00 1.20.150.10 Mainly Alpha › Up-down Bundle › Lysin › Fertilization protein 0.52 41.0 4.05e-01 95.8% 78.2%
4adnA01 1.20.1280.250 Mainly Alpha › Up-down Bundle › Monooxygenase › 0.52 31.0 3.53e-01 87.3% 81.2%
2lvfA00 1.10.110.10 Mainly Alpha › Orthogonal Bundle › Hydrophobic Seed Protein › Plant lipid-transfer and hydrophobic proteins 0.51 33.0 3.42e-01 93.2% 67.5%
3rkoF01 1.20.120.1200 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › NADH-ubiquinone/plastoquinone oxidoreductase chain 6, subunit NuoJ 0.51 33.0 2.97e-01 96.6% 48.1%
2o5iN07 1.10.132.30 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › RNA polymerase Rpb1 funnel domain 0.51 41.0 4.21e-01 87.3% 93.1%
4akgA08 1.10.472.130 Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Dynein motor, AAA2 domain, small subdomain 0.51 40.0 3.68e-01 100.0% 64.1%
2kbwA01 1.10.437.10 Mainly Alpha › Orthogonal Bundle › Apoptosis Regulator Bcl-x › Blc2-like 0.50 34.0 3.16e-01 100.0% 52.9%
ECOD (18)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3259657 605.8.1.0 ↗ alpha duplicates or obligate multimers › ROP-like › BAS1536-like › BAS1536-like 0.67 40.0 5.09e-01 89.8% 100.0%
4160317 103.2.1.2 ↗ alpha arrays › RuvA-C › ATP cone › ATP cone › ATP-cone 0.65 33.0 3.35e-01 81.4% 47.8%
4059608 5076.1.1.1 ↗ alpha complex topology › Mitochondrial ADP/ATP carrier-like › Mitochondrial ADP/ATP carrier › Mitochondrial ADP/ATP carrier › Mito_carr 0.60 51.0 3.82e-01 91.5% 84.6%
3502614 3881.1.1.1 ↗ alpha bundles › CNOT9 binding domain CN9BD (DUF3819) › CNOT9 binding domain CN9BD (DUF3819) › CNOT9 binding domain CN9BD (DUF3819) › DUF3819 0.60 50.0 3.92e-01 89.0% 51.7%
4931873 1075.1.1.12 ↗ alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain › CcmB 0.58 50.0 4.05e-01 94.1% 50.2%
3400140 5076.1.1.1 ↗ alpha complex topology › Mitochondrial ADP/ATP carrier-like › Mitochondrial ADP/ATP carrier › Mitochondrial ADP/ATP carrier › Mito_carr 0.57 49.0 3.65e-01 93.2% 83.0%
4429233 101.11.1.1 ↗ alpha arrays › HTH › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 › PNPase 0.56 37.0 4.18e-01 87.3% 91.8%
4122483 4018.1.1.1 ↗ a+b two layers › a+b domain in carbohydrate phosphatases › a+b domain in carbohydrate phosphatases › a+b domain in carbohydrate phosphatases › FBPase 0.56 43.0 3.98e-01 93.2% 62.6%
3732351 3881.1.1.1 ↗ alpha bundles › CNOT9 binding domain CN9BD (DUF3819) › CNOT9 binding domain CN9BD (DUF3819) › CNOT9 binding domain CN9BD (DUF3819) › DUF3819 0.55 48.0 3.97e-01 97.5% 64.5%
3400150 603.1.1.0 ↗ alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.55 38.0 2.89e-01 71.2% 44.2%
3373039 192.17.1.0 ↗ alpha bundles › Long alpha-hairpin › Rabenosyn-5 Rab-binding domain-like › Rabenosyn-5 Rab-binding domain-like 0.54 42.0 4.29e-01 89.8% 84.3%
3295285 3881.1.1.1 ↗ alpha bundles › CNOT9 binding domain CN9BD (DUF3819) › CNOT9 binding domain CN9BD (DUF3819) › CNOT9 binding domain CN9BD (DUF3819) › DUF3819 0.54 48.0 4.00e-01 100.0% 78.1%
3675163 3881.1.1.1 ↗ alpha bundles › CNOT9 binding domain CN9BD (DUF3819) › CNOT9 binding domain CN9BD (DUF3819) › CNOT9 binding domain CN9BD (DUF3819) › DUF3819 0.54 47.0 4.06e-01 100.0% 86.2%
4410360 1075.1.2.1 ↗ alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › MacB transmembrane domain › FtsX 0.53 45.0 3.65e-01 96.6% 89.6%
5012157 605.1.1.354 ↗ alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › MS_channel_1st_1 0.53 34.0 3.85e-01 71.2% 89.4%
3302202 3745.1.1.1 ↗ alpha bundles › Sodium/Calcium exchanger › Sodium/Calcium exchanger › Sodium/Calcium exchanger › Na_Ca_ex 0.52 42.0 3.07e-01 89.0% 69.4%
3599791 219.1.1.3 ↗ a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › UCH 0.52 40.0 2.81e-01 82.2% 89.7%
4411109 140.1.1.4 ↗ alpha bundles › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › tRNA-synt_1e,DALR_2 0.51 33.0 3.05e-01 89.8% 47.3%
D3 medium residues 3-78
PDB
Domain cluster: representative
CATH (5)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3uifA01 3.40.190.10 Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › Periplasmic binding protein-like II 0.63 35.0 2.43e-01 75.0% 18.1%
2o36A02 1.10.1370.10 Mainly Alpha › Orthogonal Bundle › Neurolysin; domain 3 › Neurolysin, domain 3 0.59 50.0 3.31e-01 100.0% 22.4%
2kfpA00 3.90.1150.30 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › 0.55 38.0 3.32e-01 73.7% 80.8%
4lw2A02 3.40.640.10 Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) 0.52 43.0 3.08e-01 94.7% 53.7%
2o8bB04 1.10.1420.10 Mainly Alpha › Orthogonal Bundle › MutS, DNA mismatch repair protein; Chain A, domain 3 › 0.52 36.0 2.97e-01 90.8% 41.2%
ECOD (5)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3742793 601.23.1.4 ↗ alpha bundles › Four-helical up-and-down bundle › DNA repair protein MutS, domain III › DNA repair protein MutS, domain III › MutS_IV, MutS_III 0.55 45.0 3.03e-01 90.8% 28.5%
4278038 2004.1.1.0 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.52 40.0 2.33e-01 86.8% 54.4%
None — 0.51 40.0 2.35e-01 89.5% 54.8%
3709669 601.23.1.4 ↗ alpha bundles › Four-helical up-and-down bundle › DNA repair protein MutS, domain III › DNA repair protein MutS, domain III › MutS_IV, MutS_III 0.51 39.0 2.67e-01 85.5% 40.6%
4066114 601.23.1.0 ↗ alpha bundles › Four-helical up-and-down bundle › DNA repair protein MutS, domain III › DNA repair protein MutS, domain III 0.50 42.0 2.90e-01 93.4% 35.6%
D4 medium residues 240-307_440-467
PDB
Domain cluster: representative
CATH (9)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2xi9A03 1.10.150.480 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › 0.59 45.0 4.50e-01 83.3% 77.2%
4krdB00 1.10.472.10 Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like 0.58 42.0 3.37e-01 76.0% 87.9%
3wiwA00 1.50.10.10 Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase › 0.54 47.0 3.22e-01 99.0% 99.5%
1euvA01 1.10.418.20 Mainly Alpha › Orthogonal Bundle › Actin-binding Protein, T-fimbrin; domain 1 › 0.52 37.0 3.60e-01 72.9% 100.0%
5xs2B02 1.10.472.10 Mainly Alpha › Orthogonal Bundle › Cyclin A; domain 1 › Cyclin-like 0.52 39.0 3.54e-01 80.2% 68.2%
4w4kA00 1.10.287.850 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HP0062-like domain 0.51 34.0 3.64e-01 100.0% 79.3%
2qe9B01 1.20.120.450 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › dinb family like domain 0.51 41.0 3.55e-01 88.5% 96.8%
2hkvA01 1.20.120.450 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › dinb family like domain 0.51 41.0 3.67e-01 88.5% 92.2%
4wk5A00 1.10.600.10 Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase 0.51 37.0 2.73e-01 77.1% 50.4%
ECOD (4)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3961109 620.1.1.5 ↗ alpha bundles › YfiT-like putative metal-dependent hydrolases › YfiT-like putative metal-dependent hydrolases › YfiT-like putative metal-dependent hydrolases › MDMPI_N 0.55 43.0 3.77e-01 85.4% 92.0%
5008722 2484.1.1.0 ↗ mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like 0.54 41.0 2.95e-01 83.3% 87.9%
3729323 5073.1.2.12 ↗ alpha bundles › Calcium ATPase transmembrane domain-related › Calcium ATPase transmembrane domain-related › Copper efflux ATPase transmembrane domain › PF30968 0.51 36.0 2.68e-01 74.0% 49.8%
3216252 5001.1.1.69 ↗ alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Srd 0.51 41.0 2.91e-01 88.5% 90.6%
D5 medium residues 308-375
PDB
Domain cluster: representative
CATH (43)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3vb0A01 3.10.180.10 Alpha Beta › Roll › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase; domain 1 › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1 0.77 52.0 4.15e-01 76.5% 37.2%
2qyvA01 3.40.630.10 Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Zn peptidases 0.73 54.0 3.59e-01 77.9% 80.9%
2v8qA01 3.30.310.80 Alpha Beta › 2-Layer Sandwich › TATA-Binding Protein › Kinase associated domain 1, KA1 0.73 52.0 4.76e-01 75.0% 58.4%
2bhoA00 3.30.1460.10 Alpha Beta › 2-Layer Sandwich › Yope Regulator; Chain: A, › 0.73 47.0 4.00e-01 70.6% 40.9%
3getA02 3.90.1150.10 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 0.72 51.0 4.56e-01 73.5% 75.5%
1yloA01 3.40.630.10 Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Zn peptidases 0.72 53.0 3.51e-01 77.9% 80.3%
2fvgA01 3.40.630.10 Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Zn peptidases 0.71 50.0 3.40e-01 73.5% 40.9%
4pxcA01 3.40.630.10 Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Zn peptidases 0.70 52.0 3.37e-01 79.4% 33.7%
2greA01 3.40.630.10 Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Zn peptidases 0.70 51.0 3.51e-01 77.9% 80.5%
1bh5A00 3.10.180.10 Alpha Beta › Roll › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase; domain 1 › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1 0.70 48.0 3.51e-01 72.1% 27.7%
1z2lA01 3.40.630.10 Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Zn peptidases 0.69 52.0 3.36e-01 79.4% 34.8%
2wyrA01 3.40.630.10 Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Zn peptidases 0.69 50.0 3.40e-01 76.5% 41.2%
3n5fA01 3.40.630.10 Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Zn peptidases 0.68 50.0 3.32e-01 79.4% 35.3%
3oajA02 3.10.180.10 Alpha Beta › Roll › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase; domain 1 › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1 0.67 51.0 3.93e-01 79.4% 74.3%
2jrbA00 3.30.250.20 Alpha Beta › 2-Layer Sandwich › Rec A Protein; domain 2 › L1 transposable element, C-terminal domain 0.67 44.0 4.50e-01 72.1% 70.8%
3ly1D01 3.90.1150.10 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 0.67 53.0 4.33e-01 86.8% 71.3%
3p8aA02 2.60.40.4320 Mainly Beta › Sandwich › Immunoglobulin-like › 0.66 43.0 3.99e-01 75.0% 51.1%
1ul7A00 3.30.310.80 Alpha Beta › 2-Layer Sandwich › TATA-Binding Protein › Kinase associated domain 1, KA1 0.66 53.0 4.66e-01 88.2% 62.7%
3ey7A01 3.10.180.10 Alpha Beta › Roll › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase; domain 1 › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1 0.66 43.0 3.57e-01 82.4% 38.0%
1vhoA01 3.40.630.10 Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Zn peptidases 0.65 47.0 3.24e-01 77.9% 83.0%
4q7aA01 3.40.630.10 Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Zn peptidases 0.65 47.0 3.26e-01 79.4% 41.5%
3kl9A01 3.40.630.10 Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Zn peptidases 0.65 48.0 3.21e-01 79.4% 40.4%
3isxA01 3.40.630.10 Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Zn peptidases 0.65 47.0 3.21e-01 77.9% 83.3%
3hdoA01 3.90.1150.10 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 0.63 50.0 4.09e-01 86.8% 70.8%
3p1tA01 3.90.1150.10 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 0.63 49.0 4.07e-01 83.8% 82.0%
3itwA02 3.30.720.110 Alpha Beta › 2-Layer Sandwich › Signal recognition particle alu RNA binding heterodimer, srp9/1 › 0.63 44.0 4.82e-01 79.4% 91.1%
3r4qA01 3.10.180.10 Alpha Beta › Roll › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase; domain 1 › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1 0.63 51.0 4.06e-01 88.2% 68.2%
1uu1B01 3.90.1150.10 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 0.62 49.0 4.01e-01 85.3% 75.6%
2i4lA01 3.30.930.10 Alpha Beta › 2-Layer Sandwich › BirA Bifunctional Protein; domain 2 › Bira Bifunctional Protein; Domain 2 0.62 52.0 3.33e-01 94.1% 91.2%
4wbtA01 3.90.1150.10 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 0.61 47.0 3.80e-01 85.3% 73.6%
2kjzA01 3.30.720.120 Alpha Beta › 2-Layer Sandwich › Signal recognition particle alu RNA binding heterodimer, srp9/1 › 0.60 38.0 4.12e-01 72.1% 81.5%
3fcdB00 3.10.180.10 Alpha Beta › Roll › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase; domain 1 › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1 0.59 45.0 3.82e-01 85.3% 90.8%
3m2oA01 3.30.720.120 Alpha Beta › 2-Layer Sandwich › Signal recognition particle alu RNA binding heterodimer, srp9/1 › 0.59 38.0 4.10e-01 70.6% 84.9%
4innA00 2.40.128.520 Mainly Beta › Beta Barrel › Lipocalin › 0.57 41.0 3.23e-01 75.0% 88.4%
1xqaA01 3.10.180.10 Alpha Beta › Roll › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase; domain 1 › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1 0.57 45.0 3.84e-01 85.3% 62.7%
4b1bA00 3.50.50.60 Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain 0.55 40.0 2.47e-01 77.9% 66.1%
3oxhA01 3.10.180.10 Alpha Beta › Roll › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase; domain 1 › 2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1 0.55 46.0 3.71e-01 94.1% 89.8%
6u9hF02 3.30.70.1150 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT-like. Chain A, domain 2 0.55 38.0 3.65e-01 72.1% 66.2%
4oagB02 3.30.460.90 Alpha Beta › 2-Layer Sandwich › Beta Polymerase; domain 2 › 0.54 43.0 3.26e-01 92.6% 79.0%
1b77A00 3.70.10.10 Alpha Beta › Box › Proliferating Cell Nuclear Antigen › 0.52 39.0 2.74e-01 80.9% 26.3%
1x99A00 2.60.270.20 Mainly Beta › Sandwich › Mutm (Fpg) Protein; Chain: A, domain 2 › Cytolysin/lectin 0.52 38.0 3.06e-01 79.4% 93.8%
1yt5A01 3.40.50.10330 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Probable inorganic polyphosphate/atp-NAD kinase; domain 1 0.51 37.0 3.04e-01 77.9% 52.3%
4n03A02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.50 38.0 2.85e-01 82.4% 50.0%
ECOD (58)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3279654 241.1.1.0 ↗ a+b two layers › Type III secretory system chaperone-like › Type III secretory system chaperone › Type III secretory system chaperone 0.81 54.0 4.24e-01 76.5% 34.8%
4944777 2011.1.1.0 ↗ a/b three-layered sandwiches › Phosphorylase/hydrolase-like › Zn-dependent exopeptidases › Zn-dependent exopeptidases 0.74 55.0 3.60e-01 77.9% 79.6%
4029007 211.1.1.0 ↗ a+b two layers › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase 0.74 45.0 4.82e-01 75.0% 70.0%
5044356 2011.1.1.11 ↗ a/b three-layered sandwiches › Phosphorylase/hydrolase-like › Zn-dependent exopeptidases › Zn-dependent exopeptidases › Peptidase_M42 0.73 54.0 3.58e-01 77.9% 83.5%
399248 2011.1.1.6 ↗ a/b three-layered sandwiches › Phosphorylase/hydrolase-like › Zn-dependent exopeptidases › Zn-dependent exopeptidases › Peptidase_M20 0.73 54.0 3.93e-01 79.4% 66.8%
3310862 211.1.1.0 ↗ a+b two layers › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase 0.72 48.0 5.13e-01 79.4% 78.3%
3984219 2011.1.1.11 ↗ a/b three-layered sandwiches › Phosphorylase/hydrolase-like › Zn-dependent exopeptidases › Zn-dependent exopeptidases › Peptidase_M42 0.72 53.0 3.48e-01 77.9% 83.6%
3969292 2011.1.1.11 ↗ a/b three-layered sandwiches › Phosphorylase/hydrolase-like › Zn-dependent exopeptidases › Zn-dependent exopeptidases › Peptidase_M42 0.72 53.0 3.51e-01 77.9% 77.4%
5052624 2011.1.1.6 ↗ a/b three-layered sandwiches › Phosphorylase/hydrolase-like › Zn-dependent exopeptidases › Zn-dependent exopeptidases › Peptidase_M20 0.72 54.0 3.53e-01 79.4% 47.3%
4994338 2011.1.1.11 ↗ a/b three-layered sandwiches › Phosphorylase/hydrolase-like › Zn-dependent exopeptidases › Zn-dependent exopeptidases › Peptidase_M42 0.71 52.0 3.48e-01 77.9% 83.3%
4964281 2011.1.1.6 ↗ a/b three-layered sandwiches › Phosphorylase/hydrolase-like › Zn-dependent exopeptidases › Zn-dependent exopeptidases › Peptidase_M20 0.71 51.0 3.46e-01 75.0% 44.3%
4034586 2011.1.1.6 ↗ a/b three-layered sandwiches › Phosphorylase/hydrolase-like › Zn-dependent exopeptidases › Zn-dependent exopeptidases › Peptidase_M20 0.70 52.0 3.44e-01 77.9% 83.0%
5036488 2011.1.1.6 ↗ a/b three-layered sandwiches › Phosphorylase/hydrolase-like › Zn-dependent exopeptidases › Zn-dependent exopeptidases › Peptidase_M20 0.70 51.0 3.50e-01 77.9% 78.0%
4200482 3016.1.1.1 ↗ a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › Aminotran_1_2 0.70 50.0 4.42e-01 73.5% 72.4%
3989230 2011.1.1.11 ↗ a/b three-layered sandwiches › Phosphorylase/hydrolase-like › Zn-dependent exopeptidases › Zn-dependent exopeptidases › Peptidase_M42 0.69 50.0 3.41e-01 77.9% 82.7%
5022425 2011.1.1.6 ↗ a/b three-layered sandwiches › Phosphorylase/hydrolase-like › Zn-dependent exopeptidases › Zn-dependent exopeptidases › Peptidase_M20 0.69 52.0 3.45e-01 79.4% 42.4%
1213130 2011.1.1.11 ↗ a/b three-layered sandwiches › Phosphorylase/hydrolase-like › Zn-dependent exopeptidases › Zn-dependent exopeptidases › Peptidase_M42 0.69 47.0 4.84e-01 76.5% 75.4%
5013512 2011.1.1.6 ↗ a/b three-layered sandwiches › Phosphorylase/hydrolase-like › Zn-dependent exopeptidases › Zn-dependent exopeptidases › Peptidase_M20 0.68 50.0 3.37e-01 77.9% 77.3%
5075779 331.4.1.0 ↗ a+b two layers › TBP-like › Kinase associated domain 1, KA1 › Kinase associated domain 1, KA1 0.68 48.0 4.56e-01 73.5% 71.2%
4041356 2011.1.1.6 ↗ a/b three-layered sandwiches › Phosphorylase/hydrolase-like › Zn-dependent exopeptidases › Zn-dependent exopeptidases › Peptidase_M20 0.68 49.0 3.33e-01 76.5% 42.0%
3282669 211.1.1.11 ↗ a+b two layers › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase › Glyoxalase_6 0.67 46.0 3.79e-01 73.5% 39.2%
3642252 331.4.1.0 ↗ a+b two layers › TBP-like › Kinase associated domain 1, KA1 › Kinase associated domain 1, KA1 0.66 46.0 4.01e-01 75.0% 49.1%
5074972 2011.1.1.6 ↗ a/b three-layered sandwiches › Phosphorylase/hydrolase-like › Zn-dependent exopeptidases › Zn-dependent exopeptidases › Peptidase_M20 0.66 49.0 3.34e-01 79.4% 42.0%
10167 2011.1.1.11 ↗ a/b three-layered sandwiches › Phosphorylase/hydrolase-like › Zn-dependent exopeptidases › Zn-dependent exopeptidases › Peptidase_M42 0.65 46.0 4.67e-01 76.5% 76.1%
5728 211.1.1.1 ↗ a+b two layers › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase › Glyoxalase 0.65 44.0 4.81e-01 77.9% 87.5%
3913070 331.4.1.3 ↗ a+b two layers › TBP-like › Kinase associated domain 1, KA1 › Kinase associated domain 1, KA1 › AdenylateSensor 0.64 52.0 4.81e-01 91.2% 68.2%
5024187 2011.1.1.6 ↗ a/b three-layered sandwiches › Phosphorylase/hydrolase-like › Zn-dependent exopeptidases › Zn-dependent exopeptidases › Peptidase_M20 0.64 46.0 3.23e-01 77.9% 81.7%
429187 330.9.1.1 ↗ a+b two layers › dsRBD-like › C-terminal domain in LINE-1 ORF1p › C-terminal domain in LINE-1 ORF1p › Tnp_22_dsRBD 0.63 45.0 4.34e-01 75.0% 96.1%
4962294 211.1.1.0 ↗ a+b two layers › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase 0.63 42.0 4.21e-01 73.5% 67.1%
3625467 316.1.1.0 ↗ a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase 0.63 52.0 4.00e-01 91.2% 67.1%
3793760 211.1.1.0 ↗ a+b two layers › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase 0.63 43.0 4.59e-01 80.9% 81.7%
3702242 331.4.1.0 ↗ a+b two layers › TBP-like › Kinase associated domain 1, KA1 › Kinase associated domain 1, KA1 0.62 51.0 4.30e-01 88.2% 56.4%
3222359 331.4.1.0 ↗ a+b two layers › TBP-like › Kinase associated domain 1, KA1 › Kinase associated domain 1, KA1 0.62 52.0 4.39e-01 89.7% 56.0%
3219274 331.4.1.0 ↗ a+b two layers › TBP-like › Kinase associated domain 1, KA1 › Kinase associated domain 1, KA1 0.62 49.0 4.49e-01 85.3% 69.7%
3490491 331.4.1.1 ↗ a+b two layers › TBP-like › Kinase associated domain 1, KA1 › Kinase associated domain 1, KA1 › KA1 0.62 49.0 4.41e-01 86.8% 65.3%
3937269 103.1.1.0 ↗ alpha arrays › RuvA-C › RuvA-C, UBA, CRAL/TRIO-N, HBS1 › UBA-like domain 0.62 51.0 3.69e-01 91.2% 33.0%
5039760 211.1.1.0 ↗ a+b two layers › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase 0.61 42.0 4.22e-01 76.5% 70.0%
3677415 331.4.1.2 ↗ a+b two layers › TBP-like › Kinase associated domain 1, KA1 › Kinase associated domain 1, KA1 › NAF 0.61 53.0 4.41e-01 97.1% 68.3%
5060093 330.7.1.2 ↗ a+b two layers › dsRBD-like › PI-Pfui intein middle domain › PI-Pfui intein middle domain › HicA_toxin 0.61 42.0 4.10e-01 70.6% 66.2%
3935896 331.4.1.0 ↗ a+b two layers › TBP-like › Kinase associated domain 1, KA1 › Kinase associated domain 1, KA1 0.60 53.0 4.23e-01 95.6% 51.5%
4994238 316.1.1.18 ↗ a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase › AbiEii 0.59 47.0 3.07e-01 94.1% 43.6%
5051779 331.4.1.0 ↗ a+b two layers › TBP-like › Kinase associated domain 1, KA1 › Kinase associated domain 1, KA1 0.59 47.0 4.04e-01 88.2% 61.8%
4407103 327.16.1.0 ↗ a+b two layers › Alpha-lytic protease prodomain-like › Ring-building motif II in type III secretion system › Ring-building motif II in type III secretion system 0.59 44.0 4.71e-01 80.9% 93.3%
5011354 316.1.1.39 ↗ a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase › DUF2204 0.58 47.0 3.53e-01 91.2% 79.5%
4990267 316.1.1.39 ↗ a+b three layers › Nucleotidyltransferase-like › Nucleotidyltransferase › Nucleotidyltransferase › DUF2204 0.58 48.0 3.55e-01 92.6% 79.3%
4976589 331.10.2.0 ↗ a+b two layers › TBP-like › S-adenosylmethionine decarboxylase-related › Bacterial S-adenosylmethionine decarboxylase 0.56 41.0 3.71e-01 91.2% 55.8%
3268843 331.18.1.4 ↗ a+b two layers › TBP-like › C-terminal TBP-like domain of Roc › C-terminal TBP-like domain of Roc › COR-B 0.56 42.0 3.18e-01 82.4% 38.9%
3739666 247.1.1.38 ↗ a+b four layers › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › CPSF73-100_C 0.55 40.0 3.65e-01 82.4% 57.8%
3205722 206.1.1.0 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase 0.55 40.0 2.82e-01 79.4% 25.8%
3471348 314.1.1.12 ↗ a+b three layers › Class II aaRS and biotin synthetases › Class II aaRS and biotin synthetases › Class II aaRS and biotin synthetases › LplA-B_cat 0.55 47.0 3.17e-01 97.1% 95.2%
5078972 331.10.2.0 ↗ a+b two layers › TBP-like › S-adenosylmethionine decarboxylase-related › Bacterial S-adenosylmethionine decarboxylase 0.54 41.0 3.84e-01 85.3% 65.9%
3496522 5.1.4.0 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed 0.53 43.0 2.66e-01 92.6% 88.1%
3252018 331.18.1.4 ↗ a+b two layers › TBP-like › C-terminal TBP-like domain of Roc › C-terminal TBP-like domain of Roc › COR-B 0.52 41.0 3.09e-01 86.8% 36.5%
3396232 331.10.2.0 ↗ a+b two layers › TBP-like › S-adenosylmethionine decarboxylase-related › Bacterial S-adenosylmethionine decarboxylase 0.51 38.0 3.42e-01 82.4% 58.0%
3168171 304.112.1.10 ↗ a+b two layers › Alpha-beta plaits › Argonaute, N-terminal domain › Argonaute, N-terminal domain › Med13_N 0.51 36.0 3.39e-01 80.9% 60.0%
1544420 2004.1.1.21 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › RecA 0.51 39.0 2.88e-01 83.8% 73.6%
3514864 211.1.1.0 ↗ a+b two layers › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase 0.51 34.0 3.73e-01 80.9% 85.5%
3990829 59.1.1.2 ↗ beta complex topology › triple barrel › triple barrel › Rap30/74 interaction domains-like › RNA_pol_Rpc4 0.50 34.0 2.90e-01 70.6% 53.4%
D6 medium residues 376-439
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF01028.26 best Topoisom_I 29.5 6.80e-07 93.8% 20.2%
CATH (39)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3m4aA03 3.90.15.10 Alpha Beta › Alpha-Beta Complex › Topoisomerase I; Chain A, domain 3 › Topoisomerase I; Chain A, domain 3 0.86 70.0 5.65e-01 100.0% 47.5%
2h7fX02 3.90.15.10 Alpha Beta › Alpha-Beta Complex › Topoisomerase I; Chain A, domain 3 › Topoisomerase I; Chain A, domain 3 0.80 68.0 4.50e-01 100.0% 24.5%
1a31A03 3.90.15.10 Alpha Beta › Alpha-Beta Complex › Topoisomerase I; Chain A, domain 3 › Topoisomerase I; Chain A, domain 3 0.75 68.0 5.10e-01 100.0% 42.7%
1a41A01 3.90.15.10 Alpha Beta › Alpha-Beta Complex › Topoisomerase I; Chain A, domain 3 › Topoisomerase I; Chain A, domain 3 0.73 59.0 4.73e-01 98.4% 44.9%
5jk0B01 1.10.443.10 Mainly Alpha › Orthogonal Bundle › hpI Integrase; Chain A › Intergrase catalytic core 0.66 56.0 4.13e-01 98.4% 35.8%
1ci3M02 2.40.50.100 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › RNA polymerase II/Efflux pump adaptor protein, barrel-sandwich hybrid domain 0.62 42.0 4.40e-01 98.4% 77.6%
3c4bA02 3.30.160.20 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › 0.62 36.0 3.57e-01 71.9% 52.2%
1nr4C00 2.40.50.40 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › 0.61 43.0 4.36e-01 87.5% 75.8%
4jn7A01 3.30.390.10 Alpha Beta › 2-Layer Sandwich › Enolase-like; domain 1 › Enolase-like, N-terminal domain 0.60 41.0 3.40e-01 100.0% 38.7%
1ykdB02 3.30.450.40 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › GAF domain 0.60 49.0 3.60e-01 93.8% 78.6%
1eqtA00 2.40.50.40 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › 0.60 43.0 4.31e-01 78.1% 74.6%
2w9jA00 3.30.720.10 Alpha Beta › 2-Layer Sandwich › Signal recognition particle alu RNA binding heterodimer, srp9/1 › Signal recognition particle alu RNA binding heterodimer, srp9/1 0.60 37.0 3.60e-01 70.3% 54.9%
2d42A02 3.10.450.380 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.59 40.0 4.03e-01 70.3% 83.1%
3k44B00 3.30.2450.30 Alpha Beta › 2-Layer Sandwich › Secreted effector protein pipB2 fold › 0.58 43.0 3.36e-01 79.7% 89.3%
5mmiG01 3.90.930.12 Alpha Beta › Alpha-Beta Complex › Outer Surface Protein A; domain 3 › Ribosomal protein L6 0.57 38.0 3.55e-01 95.3% 52.4%
4hcsA00 2.40.50.40 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › 0.57 42.0 4.23e-01 89.1% 77.6%
7tzoA01 1.10.1070.11 Mainly Alpha › Orthogonal Bundle › Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, Domain 5 › Phosphatidylinositol 3-/4-kinase, catalytic domain 0.57 43.0 3.17e-01 82.8% 54.6%
1gutA00 2.40.50.100 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › RNA polymerase II/Efflux pump adaptor protein, barrel-sandwich hybrid domain 0.56 39.0 3.90e-01 98.4% 70.1%
5tprA02 1.20.1090.10 Mainly Alpha › Up-down Bundle › Dehydroquinate synthase-like, alpha domain › Dehydroquinate synthase-like - alpha domain 0.56 46.0 3.29e-01 93.8% 85.6%
2b4wA00 2.115.10.20 Mainly Beta › 5 Propeller › Tachylectin-2; Chain A › Glycosyl hydrolase domain; family 43 0.56 42.0 2.76e-01 82.8% 88.0%
2x5cA01 3.30.70.3590 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.56 39.0 3.57e-01 76.6% 63.7%
1y96A00 2.30.30.100 Mainly Beta › Roll › SH3 type barrels. › 0.56 43.0 3.95e-01 85.9% 66.3%
2wtzA02 3.40.1190.10 Alpha Beta › 3-Layer(aba) Sandwich › UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase › Mur-like, catalytic domain 0.55 38.0 2.65e-01 73.4% 28.6%
3uoxB01 3.50.50.60 Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain 0.55 43.0 2.83e-01 85.9% 97.3%
1iucA00 2.120.10.70 Mainly Beta › 6 Propeller › Neuraminidase › Fucose-specific lectin 0.55 46.0 3.02e-01 98.4% 80.1%
2ffgA00 3.30.720.20 Alpha Beta › 2-Layer Sandwich › Signal recognition particle alu RNA binding heterodimer, srp9/1 › Protein of unknown function DUF1797 0.53 38.0 3.56e-01 93.8% 61.3%
3buxB03 3.30.505.10 Alpha Beta › 2-Layer Sandwich › SHC Adaptor Protein › SH2 domain 0.53 44.0 4.04e-01 100.0% 69.8%
4qxaB00 2.30.29.230 Mainly Beta › Roll › PH-domain like › 0.53 41.0 3.33e-01 92.2% 55.8%
7kfuC02 1.20.120.920 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › CRISPR-associated endonuclease Cas1, C-terminal domain 0.52 38.0 2.64e-01 89.1% 22.3%
5cflA02 3.40.50.12100 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Stimulator of interferon genes protein 0.52 36.0 2.79e-01 71.9% 74.8%
2eenA00 2.40.320.10 Mainly Beta › Beta Barrel › Hypothetical Protein Pfu-838710-001 › Hypothetical Protein Pfu-838710-001 0.52 40.0 2.98e-01 85.9% 40.7%
5oomJ01 3.30.1550.10 Alpha Beta › 2-Layer Sandwich › Ribosomal protein L11, N-terminal domain › Ribosomal protein L11/L12, N-terminal domain 0.51 36.0 3.61e-01 95.3% 74.2%
1e0bA00 2.40.50.40 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › 0.51 37.0 3.85e-01 82.8% 85.2%
4bwgD00 2.40.50.110 Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › 0.51 41.0 3.73e-01 96.9% 87.6%
1ywuA00 2.40.10.220 Mainly Beta › Beta Barrel › Thrombin, subunit H › predicted glycosyltransferase like domains 0.51 42.0 3.47e-01 93.8% 86.4%
2v4dE01 2.40.420.20 Mainly Beta › Beta Barrel › conserved putative lor/sdh protein from methanococcus maripaludis s2 fold › 0.51 41.0 3.84e-01 93.8% 76.2%
1ri6A00 2.130.10.10 Mainly Beta › 7 Propeller › Methylamine Dehydrogenase; Chain H › YVTN repeat-like/Quinoprotein amine dehydrogenase 0.51 42.0 2.74e-01 98.4% 95.2%
4kghA00 3.15.10.10 Alpha Beta › Super Roll › Bactericidal permeability-increasing protein; domain 1 › Bactericidal permeability-increasing protein; domain 1 0.51 40.0 3.05e-01 96.9% 68.4%
2k49A00 2.30.29.80 Mainly Beta › Roll › PH-domain like › 0.50 41.0 3.39e-01 90.6% 73.7%
ECOD (63)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3282325 101.1.8.2 ↗ alpha arrays › HTH › HTH › DNA breaking-rejoining enzymes › Topoisom_I 0.85 71.0 5.27e-01 100.0% 37.4%
5044666 101.1.8.2 ↗ alpha arrays › HTH › HTH › DNA breaking-rejoining enzymes › Topoisom_I 0.81 73.0 5.38e-01 100.0% 48.1%
3599060 101.1.8.0 ↗ alpha arrays › HTH › HTH › DNA breaking-rejoining enzymes 0.81 68.0 4.72e-01 100.0% 29.5%
138326 101.1.8.2 ↗ alpha arrays › HTH › HTH › DNA breaking-rejoining enzymes › Topoisom_I 0.80 68.0 5.19e-01 100.0% 42.4%
4988246 300.1.1.6 ↗ a+b three layers › Phospholipase D/nuclease › Phospholipase D/nuclease › Phospholipase D/nuclease › Regulator_TrmB 0.77 56.0 4.35e-01 76.6% 74.8%
3886079 101.1.8.2 ↗ alpha arrays › HTH › HTH › DNA breaking-rejoining enzymes › Topoisom_I 0.75 67.0 4.66e-01 100.0% 31.2%
5035060 101.1.8.0 ↗ alpha arrays › HTH › HTH › DNA breaking-rejoining enzymes 0.75 61.0 4.98e-01 90.6% 55.8%
4357768 101.1.8.0 ↗ alpha arrays › HTH › HTH › DNA breaking-rejoining enzymes 0.74 59.0 4.69e-01 98.4% 43.1%
4654713 300.1.1.0 ↗ a+b three layers › Phospholipase D/nuclease › Phospholipase D/nuclease › Phospholipase D/nuclease 0.74 55.0 4.22e-01 81.2% 35.2%
5028306 101.1.8.1 ↗ alpha arrays › HTH › HTH › DNA breaking-rejoining enzymes › Phage_integrase 0.74 61.0 4.46e-01 98.4% 33.3%
4253165 101.1.8.1 ↗ alpha arrays › HTH › HTH › DNA breaking-rejoining enzymes › Phage_integrase 0.72 62.0 4.88e-01 98.4% 45.0%
4947463 101.1.8.0 ↗ alpha arrays › HTH › HTH › DNA breaking-rejoining enzymes 0.72 53.0 4.54e-01 98.4% 48.6%
3291526 101.1.8.0 ↗ alpha arrays › HTH › HTH › DNA breaking-rejoining enzymes 0.71 62.0 4.54e-01 98.4% 56.6%
3804378 263.1.1.1 ↗ a+b three layers › SRF-like › SRF-like › SRF-like › SRF-TF 0.71 36.0 3.38e-01 87.5% 41.3%
3987739 207.4.1.6 ↗ beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › C-CAP/cofactor C-like › C-CAP/cofactor C-like › CFSR 0.70 40.0 2.65e-01 89.1% 15.0%
3383138 2.1.1.0 ↗ beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein 0.69 56.0 5.30e-01 98.4% 74.4%
5001443 300.1.1.0 ↗ a+b three layers › Phospholipase D/nuclease › Phospholipase D/nuclease › Phospholipase D/nuclease 0.68 48.0 3.88e-01 76.6% 81.5%
3287619 207.2.1.20 ↗ beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Pectin lyase-like › Pectin lyase-like › Pectate_lyase_3 0.66 41.0 2.48e-01 75.0% 9.4%
2983288 101.1.2.0 ↗ alpha arrays › HTH › HTH › winged helix domain 0.65 45.0 4.13e-01 75.0% 71.9%
5082761 101.1.8.1 ↗ alpha arrays › HTH › HTH › DNA breaking-rejoining enzymes › Phage_integrase 0.64 54.0 4.34e-01 98.4% 46.9%
4890599 1.1.7.80 ↗ beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C › RND-MFP_C 0.64 39.0 3.95e-01 73.4% 59.1%
4625348 325.1.7.3 ↗ a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif › Apocytochr_F_C 0.63 42.0 4.35e-01 98.4% 73.3%
4930437 220.1.1.219 ↗ beta barrels › PH domain-like › PH domain-like › PH domain-like › CheF-arch 0.63 51.0 4.41e-01 92.2% 62.9%
3973145 4.8.1.0 ↗ beta barrels › SH3 › Chromo domain-like › Chromo domain-like 0.62 40.0 4.25e-01 71.9% 78.2%
1168794 330.1.1.8 ↗ a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like › Dicer_dsRBD 0.62 36.0 3.19e-01 71.9% 36.8%
4944386 220.1.1.0 ↗ beta barrels › PH domain-like › PH domain-like › PH domain-like 0.61 50.0 4.26e-01 93.8% 60.0%
5054141 2.14.1.0 ↗ beta barrels › OB-fold › HupF/HypC-like › HupF/HypC-like 0.61 40.0 4.33e-01 98.4% 86.0%
3815957 5.1.3.67 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed › FBA_1 0.60 49.0 3.13e-01 92.2% 98.1%
4277215 300.1.1.6 ↗ a+b three layers › Phospholipase D/nuclease › Phospholipase D/nuclease › Phospholipase D/nuclease › Regulator_TrmB 0.60 51.0 3.83e-01 96.9% 43.3%
3255946 220.1.1.0 ↗ beta barrels › PH domain-like › PH domain-like › PH domain-like 0.59 47.0 4.47e-01 90.6% 85.0%
3487901 4263.2.1.0 ↗ a+b two layers › TTHA1528-like › FtsH Periplasmic Domain › FtsH Periplasmic Domain 0.59 48.0 4.60e-01 92.2% 82.7%
4492087 325.1.7.3 ↗ a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif › Apocytochr_F_C 0.58 43.0 4.32e-01 98.4% 78.5%
4349950 325.1.7.0 ↗ a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif 0.58 42.0 4.34e-01 100.0% 83.3%
4435672 325.1.7.0 ↗ a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif 0.57 41.0 4.13e-01 100.0% 76.9%
4099964 325.1.7.3 ↗ a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif › Apocytochr_F_C 0.57 42.0 4.20e-01 98.4% 78.5%
3941152 4.8.1.0 ↗ beta barrels › SH3 › Chromo domain-like › Chromo domain-like 0.57 38.0 3.88e-01 100.0% 69.2%
5017964 220.1.1.322 ↗ beta barrels › PH domain-like › PH domain-like › PH domain-like › DUF6141 0.56 41.0 3.72e-01 78.1% 75.3%
4119875 325.1.7.0 ↗ a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif 0.56 40.0 4.07e-01 100.0% 76.9%
4117297 4.1.1.0 ↗ beta barrels › SH3 › SH3 › SH3 0.55 35.0 3.45e-01 73.4% 58.6%
4975450 300.1.1.0 ↗ a+b three layers › Phospholipase D/nuclease › Phospholipase D/nuclease › Phospholipase D/nuclease 0.55 39.0 3.38e-01 78.1% 42.4%
4456732 325.1.7.0 ↗ a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif 0.55 40.0 3.75e-01 100.0% 62.5%
3786015 5.1.5.1 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 8-bladed › WD40 0.55 44.0 2.53e-01 90.6% 33.6%
3222570 220.1.1.0 ↗ beta barrels › PH domain-like › PH domain-like › PH domain-like 0.55 42.0 3.55e-01 85.9% 49.6%
3786356 7502.1.1.0 ↗ a/b three-layered sandwiches › Anticodon-binding domain of Class II aaRS › Anticodon-binding domain of Class II aaRS › Anticodon-binding domain of Class II aaRS 0.55 41.0 3.47e-01 81.2% 98.2%
4280539 109.21.1.8 ↗ alpha superhelices › Repetitive alpha hairpins › Nucleoporin NUP85/Nucleoporin NUP145 C-terminal domain › Nucleoporin NUP85/Nucleoporin NUP145 C-terminal domain › WD40 0.54 43.0 2.48e-01 90.6% 31.0%
3662757 206.1.1.20 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › PK_Tyr_Ser-Thr 0.54 41.0 2.96e-01 84.4% 30.7%
3472026 220.1.1.27 ↗ beta barrels › PH domain-like › PH domain-like › PH domain-like › PH_RBD 0.54 42.0 3.46e-01 85.9% 72.5%
3509521 101.1.1.0 ↗ alpha arrays › HTH › HTH › Three-helical HTH 0.53 41.0 3.17e-01 84.4% 81.3%
4856688 220.1.1.0 ↗ beta barrels › PH domain-like › PH domain-like › PH domain-like 0.53 41.0 3.97e-01 89.1% 76.0%
3701985 2004.1.1.427 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › RHSP, RHS_N 0.53 44.0 2.72e-01 98.4% 38.4%
4184523 1.1.7.80 ↗ beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C › RND-MFP_C 0.52 43.0 3.80e-01 95.3% 87.0%
4937843 2005.1.1.7 ↗ a/b three-layered sandwiches › HUP domain-like › HUP domains › HUP domains › tRNA-synt_1d 0.52 40.0 2.51e-01 84.4% 17.6%
3574069 604.12.1.62 ↗ alpha bundles › Spectrin repeat-like › MIT domain › MIT domain › DuoxA 0.52 38.0 3.05e-01 79.7% 40.0%
3573585 4.8.1.0 ↗ beta barrels › SH3 › Chromo domain-like › Chromo domain-like 0.52 38.0 4.07e-01 87.5% 94.4%
5011439 802.1.1.0 ↗ a+b two layers › Hypothetical protein TM0160 › Hypothetical protein TM0160 › Hypothetical protein TM0160 0.52 44.0 3.49e-01 100.0% 87.6%
3587237 252.2.1.2 ↗ a+b two layers › DNA-binding domain › GCC-box binding domain-like › GCC-box binding domain-like › Integrase_DNA 0.52 40.0 3.81e-01 89.1% 70.7%
5057630 2008.1.1.107 ↗ a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › NERD 0.52 40.0 2.99e-01 85.9% 43.5%
3170899 7502.1.1.0 ↗ a/b three-layered sandwiches › Anticodon-binding domain of Class II aaRS › Anticodon-binding domain of Class II aaRS › Anticodon-binding domain of Class II aaRS 0.52 40.0 3.49e-01 87.5% 70.5%
4559415 2004.1.1.0 ↗ a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.51 43.0 2.66e-01 100.0% 52.6%
4056113 1.1.7.80 ↗ beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C › RND-MFP_C 0.51 41.0 3.65e-01 93.8% 67.0%
3263687 5.1.4.276 ↗ beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › WD40, Beta-prop_WDR75_2nd 0.51 42.0 2.74e-01 96.9% 81.8%
3547409 604.1.1.153 ↗ alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › DUF4455 0.51 41.0 2.87e-01 87.5% 79.5%
3307884 206.1.1.74 ↗ a+b complex topology › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase/SAICAR synthase/ATP-grasp › Protein kinase › Pkinase, PK_Tyr_Ser-Thr 0.50 43.0 2.85e-01 98.4% 55.9%