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IMGVR_UViG_2811995110_000237-2811995110-2813159654

Arc-Vir

IMGVR_UViG_2811995110_000237-2811995110-2813159654

Identity

Kingdom:
archaea

Quality

76.1 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 497-574
PDB
Domain cluster: representative
CATH (42)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3fnrA01 1.10.730.10 Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 0.73 53.0 4.23e-01 75.6% 51.7%
4hehA01 1.10.1240.10 Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › Methionine synthase domain 0.72 57.0 5.68e-01 88.5% 97.6%
8d7hD01 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.72 54.0 4.03e-01 78.2% 61.8%
3zgzA04 1.10.730.10 Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 0.70 48.0 3.64e-01 70.5% 39.0%
4ezbA02 1.10.1040.10 Mainly Alpha › Orthogonal Bundle › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 0.70 53.0 4.55e-01 79.5% 80.3%
2fji101 1.10.357.50 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › 0.69 56.0 4.13e-01 89.7% 64.1%
2c5iT00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.68 50.0 4.71e-01 78.2% 89.4%
2p0vA01 1.50.10.10 Mainly Alpha › Alpha/alpha barrel › Glycosyltransferase › 0.67 60.0 3.73e-01 100.0% 50.3%
3qsgA02 1.10.1040.10 Mainly Alpha › Orthogonal Bundle › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 0.67 51.0 4.45e-01 80.8% 80.9%
6hrdA01 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.67 52.0 3.92e-01 84.6% 34.6%
1uurA01 1.20.58.240 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › STAT; domain 1 0.66 50.0 4.40e-01 79.5% 87.3%
4kb2A01 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.66 46.0 4.16e-01 74.4% 87.2%
3ztaA00 1.10.490.130 Mainly Alpha › Orthogonal Bundle › Globin-like › 0.66 53.0 4.45e-01 91.0% 67.6%
4jxtA00 1.25.40.90 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.65 54.0 4.56e-01 91.0% 64.6%
3bvoB01 1.10.287.110 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › DnaJ domain 0.65 49.0 4.58e-01 82.1% 83.7%
2wvxA04 1.20.1610.10 Mainly Alpha › Up-down Bundle › Glycosyl hydrolase family fold › alpha-1,2-mannosidases domains 0.63 49.0 3.79e-01 87.2% 37.6%
2e9xD01 1.20.58.1030 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.62 46.0 3.81e-01 78.2% 52.6%
3anwA01 1.20.58.1030 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.62 51.0 4.40e-01 85.9% 61.1%
3lwjA00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.61 53.0 4.06e-01 100.0% 66.3%
2es9A00 1.20.1290.30 Mainly Alpha › Up-down Bundle › AhpD-like › 0.60 47.0 4.45e-01 88.5% 76.0%
1q0gA00 1.20.120.400 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nickel-containing superoxide dismutase 0.60 48.0 4.13e-01 84.6% 69.2%
2yfkA02 3.40.50.1370 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Aspartate/ornithine carbamoyltransferase 0.60 41.0 3.09e-01 88.5% 28.1%
4d3dB02 1.10.1040.10 Mainly Alpha › Orthogonal Bundle › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 0.59 42.0 3.61e-01 74.4% 75.2%
3deeA01 1.10.150.690 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › DUF2063 0.59 51.0 4.98e-01 96.2% 97.7%
1rrmA02 1.20.1090.10 Mainly Alpha › Up-down Bundle › Dehydroquinate synthase-like, alpha domain › Dehydroquinate synthase-like - alpha domain 0.59 45.0 3.43e-01 84.6% 72.0%
3bgeA01 1.20.272.10 Mainly Alpha › Up-down Bundle › Zinc Finger, Delta Prime; domain 3 › 0.59 47.0 4.48e-01 89.7% 80.2%
2c0kB00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.58 48.0 3.97e-01 93.6% 62.4%
1i36A02 1.10.1040.10 Mainly Alpha › Orthogonal Bundle › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 0.58 40.0 3.74e-01 73.1% 88.9%
1ecaA00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.57 47.0 4.05e-01 96.2% 62.5%
3qxlA00 1.10.840.10 Mainly Alpha › Orthogonal Bundle › Son of Sevenless (SoS) protein; Chain S, domain 2 › Ras guanine-nucleotide exchange factors catalytic domain 0.57 45.0 3.30e-01 91.0% 39.6%
2fp1B00 1.20.59.10 Mainly Alpha › Up-down Bundle › Chorismate Mutase Domain, subunit A › Chorismate mutase 0.57 45.0 3.60e-01 88.5% 100.0%
5ts9B00 1.20.59.10 Mainly Alpha › Up-down Bundle › Chorismate Mutase Domain, subunit A › Chorismate mutase 0.56 43.0 3.52e-01 85.9% 100.0%
1e6bA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.56 42.0 3.80e-01 82.1% 74.8%
3tahA02 1.10.287.1770 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.55 43.0 4.17e-01 87.2% 73.9%
2ip6A00 1.20.1440.140 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 0.55 40.0 3.88e-01 76.9% 92.0%
3eupB00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.55 46.0 3.50e-01 96.2% 85.0%
1dpgA02 3.30.360.10 Alpha Beta › 2-Layer Sandwich › Dihydrodipicolinate Reductase; domain 2 › Dihydrodipicolinate Reductase; domain 2 0.54 45.0 3.04e-01 92.3% 79.9%
3knwB00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.54 41.0 3.21e-01 82.1% 84.7%
6xy4A01 1.10.437.10 Mainly Alpha › Orthogonal Bundle › Apoptosis Regulator Bcl-x › Blc2-like 0.52 41.0 3.63e-01 88.5% 63.4%
2og9A01 3.30.390.10 Alpha Beta › 2-Layer Sandwich › Enolase-like; domain 1 › Enolase-like, N-terminal domain 0.52 41.0 3.50e-01 85.9% 82.3%
1ekjA00 3.40.1050.10 Alpha Beta › 3-Layer(aba) Sandwich › Beta-carbonic Anhydrase; Chain A › Carbonic anhydrase 0.50 42.0 3.23e-01 100.0% 78.6%
3b5iA02 1.10.1200.220 Mainly Alpha › Orthogonal Bundle › Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A › 0.50 40.0 3.81e-01 89.7% 84.2%
ECOD (37)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4007623 220.1.1.150 beta barrels › PH domain-like › PH domain-like › PH domain-like › DUF986 0.82 57.0 5.37e-01 70.5% 95.6%
3666430 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.81 69.0 4.12e-01 91.0% 15.6%
3256951 6155.1.1.2 alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter › PQ-loop 0.76 52.0 4.52e-01 70.5% 67.0%
3506685 1134.1.1.0 alpha bundles › C-terminal helical domain of alanine-tRNA ligase › C-terminal helical domain of alanine-tRNA ligase › Eukaryotic C-Ala helical domain 0.75 53.0 5.46e-01 74.4% 86.7%
5073599 4156.1.1.1 alpha arrays › Sec63 N-terminal subdomain-like › Sec63 N-terminal subdomain-like › Sec63 N-terminal subdomain-like › Sec63 0.73 57.0 4.67e-01 80.8% 96.9%
3938965 5001.1.1.0 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like 0.70 55.0 3.78e-01 82.1% 41.6%
3441147 604.3.1.0 alpha bundles › Spectrin repeat-like › BAG domain › BAG domain 0.70 50.0 4.88e-01 74.4% 84.7%
3628598 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.70 55.0 5.53e-01 83.3% 91.3%
4945528 140.1.1.11 alpha bundles › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › DALR_1 0.69 51.0 3.78e-01 78.2% 39.5%
4249191 140.1.1.7 alpha bundles › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › DALR_2 0.68 48.0 3.93e-01 73.1% 47.1%
3227805 5001.1.1.63 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Srab 0.68 55.0 3.62e-01 85.9% 39.0%
3361553 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.68 51.0 4.96e-01 78.2% 81.2%
3590608 7516.1.1.2 a/b three-layered sandwiches › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Nucleotide-diphospho-sugar transferases › Glycos_transf_2 0.68 60.0 4.05e-01 96.2% 58.5%
3635931 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.68 60.0 3.74e-01 100.0% 38.9%
3940557 310.2.1.0 a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF 0.67 58.0 4.80e-01 91.0% 83.8%
4855700 4995.1.1.1 alpha arrays › Methionine synthase domain-like › Methionine synthase domain-like › Methionine synthase domain-like › B12-binding_2 0.67 47.0 4.91e-01 73.1% 100.0%
5060383 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.67 47.0 4.83e-01 74.4% 96.0%
3939938 103.4.1.1 alpha arrays › RuvA-C › Elongation factor TFIIS domain 2/ Kix domain of creb binding protein › Elongation factor TFIIS domain 2/ Kix domain of creb binding protein › KIX 0.66 42.0 4.07e-01 89.7% 58.8%
5002237 3930.1.1.3 alpha bundles › Helical bundle insertion in helicase domains › Helical bundle in Hef helicase › Helical bundle in Hef helicase › RNA_helicase_helical 0.66 46.0 3.89e-01 76.9% 43.0%
4134592 218.1.1.8 a+b two layers › Enolase-N/ribosomal protein › Enolase N-terminal domain-like › Enolase N-terminal domain-like › HrcA 0.65 53.0 4.86e-01 85.9% 98.0%
3631283 5069.1.1.82 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › PigN 0.64 46.0 3.45e-01 75.6% 78.5%
4430705 1197.1.1.1 alpha bundles › Integral membrane glycerol 3-phosphate acyltransferase PlsY › Integral membrane glycerol 3-phosphate acyltransferase PlsY › Integral membrane glycerol 3-phosphate acyltransferase PlsY › G3P_acyltransf 0.64 52.0 4.07e-01 91.0% 70.4%
3726873 601.1.2.108 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › PigN 0.64 46.0 3.50e-01 75.6% 76.7%
4958742 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.63 47.0 4.04e-01 79.5% 70.4%
3309050 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.63 48.0 3.64e-01 82.1% 36.5%
4653062 604.4.1.0 alpha bundles › Spectrin repeat-like › Alpha-hemoglobin stabilizing protein AHSP › Alpha-hemoglobin stabilizing protein AHSP 0.63 43.0 3.84e-01 70.5% 81.8%
3218875 192.7.1.58 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › PigN 0.61 47.0 3.64e-01 80.8% 72.1%
3744377 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.61 54.0 3.79e-01 100.0% 66.9%
4177919 1197.1.1.1 alpha bundles › Integral membrane glycerol 3-phosphate acyltransferase PlsY › Integral membrane glycerol 3-phosphate acyltransferase PlsY › Integral membrane glycerol 3-phosphate acyltransferase PlsY › G3P_acyltransf 0.61 51.0 3.77e-01 94.9% 65.1%
4465167 186.1.1.1 alpha arrays › lambda integrase-N-like › lambda integrase-N › lambda integrase-N › Phage_int_SAM_1 0.59 41.0 3.71e-01 73.1% 70.0%
3764523 140.1.1.4 alpha bundles › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › tRNA-synt_1e,DALR_2 0.59 42.0 3.29e-01 74.4% 43.5%
3743652 109.4.1.451 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Iml2-TPR_39 0.58 50.0 3.50e-01 96.2% 30.8%
5027489 129.1.1.3 alpha arrays › 6-phosphogluconate dehydrogenase C-terminal domain-like › 6-phosphogluconate dehydrogenase C-terminal domain-like › 6-phosphogluconate dehydrogenase C-terminal domain-like › UDPG_MGDP_dh 0.58 45.0 4.07e-01 83.3% 83.8%
4412725 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.57 51.0 3.88e-01 100.0% 71.1%
5002351 304.48.1.1 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 0.54 44.0 2.93e-01 93.6% 39.7%
4052199 4163.1.1.1 alpha bundles › GINS helical bundle-like › GINS helical bundle-like › PSF1 N-terminal domain-like › Sld5 0.52 44.0 3.50e-01 96.2% 68.5%
3372933 3236.1.1.1 alpha complex topology › Cation-proton antiporter › Cation-proton antiporter (CPA) › Cation-proton antiporter (CPA) › Na_H_Exchanger 0.51 41.0 2.90e-01 93.6% 34.2%
D2 medium residues 14-74
PDB
Domain cluster: representative
CATH (2)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1ps9A01 3.20.20.70 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I 0.54 36.0 2.26e-01 70.5% 34.8%
1kx5A00 1.10.20.10 Mainly Alpha › Orthogonal Bundle › Histone, subunit A › Histone, subunit A 0.53 38.0 3.00e-01 78.7% 41.5%
ECOD (2)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3832771 2006.1.1.8 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like › 5_nucleotid 0.64 48.0 2.97e-01 80.3% 83.0%
1291955 3881.1.1.1 alpha bundles › CNOT9 binding domain CN9BD (DUF3819) › CNOT9 binding domain CN9BD (DUF3819) › CNOT9 binding domain CN9BD (DUF3819) › DUF3819 0.55 43.0 3.02e-01 91.8% 68.6%
D3 medium residues 176-264
PDB
Domain cluster: representative
CATH (17)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3k1lA01 3.30.457.40 Alpha Beta › 2-Layer Sandwich › Copper Amine Oxidase; Chain A, domain 1 › 0.62 34.0 3.45e-01 92.1% 52.2%
5bw0F00 3.30.1300.30 Alpha Beta › 2-Layer Sandwich › Pantoate--beta-alanine Ligase; Chain: A,domain 2 › GSPII I/J protein-like 0.60 39.0 3.89e-01 89.9% 64.8%
2gfgA00 2.40.320.10 Mainly Beta › Beta Barrel › Hypothetical Protein Pfu-838710-001 › Hypothetical Protein Pfu-838710-001 0.58 37.0 2.94e-01 98.9% 30.4%
3kg7B00 3.10.129.110 Alpha Beta › Roll › Thiol Ester Dehydrase; Chain A › Polyketide synthase dehydratase 0.57 51.0 3.54e-01 97.8% 63.9%
3d2uE01 3.30.500.10 Alpha Beta › 2-Layer Sandwich › Murine Class I Major Histocompatibility Complex, H2-DB; Chain A, domain 1 › MHC class I-like antigen recognition-like 0.56 49.0 3.83e-01 95.5% 92.0%
3sxxC01 3.10.450.40 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.56 40.0 3.88e-01 97.8% 65.7%
1qwoA01 3.40.50.1240 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Phosphoglycerate mutase-like 0.56 45.0 2.96e-01 88.8% 95.4%
3loyA01 3.10.450.40 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.55 41.0 3.99e-01 95.5% 69.3%
6e20A00 2.60.120.200 Mainly Beta › Sandwich › Jelly Rolls › 0.54 49.0 4.27e-01 98.9% 81.8%
1clwA00 2.160.20.20 Mainly Beta › 3 Solenoid › Pectate Lyase C-like › 0.54 36.0 2.21e-01 92.1% 11.0%
3bnvD00 3.10.129.10 Alpha Beta › Roll › Thiol Ester Dehydrase; Chain A › Hotdog Thioesterase 0.54 47.0 4.00e-01 95.5% 70.6%
3wucB00 2.60.120.200 Mainly Beta › Sandwich › Jelly Rolls › 0.53 48.0 4.14e-01 98.9% 78.1%
2o62A01 2.40.128.20 Mainly Beta › Beta Barrel › Lipocalin › Calycin beta-barrel core domain 0.51 38.0 3.37e-01 100.0% 52.7%
3l9rA01 3.30.500.10 Alpha Beta › 2-Layer Sandwich › Murine Class I Major Histocompatibility Complex, H2-DB; Chain A, domain 1 › MHC class I-like antigen recognition-like 0.51 45.0 3.60e-01 96.6% 92.6%
6gbuD00 2.30.30.40 Mainly Beta › Roll › SH3 type barrels. › SH3 Domains 0.51 31.0 3.51e-01 82.0% 82.8%
2ownA00 3.10.129.10 Alpha Beta › Roll › Thiol Ester Dehydrase; Chain A › Hotdog Thioesterase 0.50 44.0 3.22e-01 98.9% 65.6%
1ywqA00 3.40.109.10 Alpha Beta › 3-Layer(aba) Sandwich › NADH Oxidase › NADH Oxidase 0.50 43.0 3.38e-01 97.8% 62.3%
ECOD (27)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3963566 4056.1.1.5 beta barrels › Barrel domain in upper collar protein › Barrel domain in upper collar protein › Barrel domain in upper collar protein › P22_portal 0.77 71.0 5.90e-01 100.0% 64.4%
4891117 4038.1.1.11 alpha bundles › Alpha-helical domain in upper collar protein › Alpha-helical domain in upper collar protein › Alpha-helical domain in upper collar protein › SU10_portal 0.70 63.0 3.84e-01 100.0% 18.3%
3930600 243.5.1.0 a+b two layers › Cystatin-like › Amine oxidase N-terminal region › Amine oxidase N-terminal region 0.68 46.0 4.64e-01 85.4% 68.9%
2537708 4056.1.1.4 beta barrels › Barrel domain in upper collar protein › Barrel domain in upper collar protein › Barrel domain in upper collar protein › Head-tail_con 0.68 56.0 4.87e-01 100.0% 59.4%
4083689 283.2.1.1 a+b duplicates or obligate multimers › Creatinase/aminopeptidase-like › gpW/gp25-like › gpW/gp25-like › GPW_gp25 0.67 35.0 3.27e-01 85.4% 41.3%
3959737 222.1.1.0 a+b two layers › Thioesterase/thiol ester dehydrase-isomerase-like › Thioesterase/thiol ester dehydrase-isomerase › Thioesterase/thiol ester dehydrase-isomerase 0.58 51.0 4.32e-01 94.4% 79.3%
3737819 243.5.1.1 a+b two layers › Cystatin-like › Amine oxidase N-terminal region › Amine oxidase N-terminal region › Cu_amine_oxidN2 0.58 42.0 4.11e-01 95.5% 70.5%
3592832 4.1.1.0 beta barrels › SH3 › SH3 › SH3 0.57 47.0 3.93e-01 88.8% 63.9%
3443454 10.1.1.2 beta sandwiches › jelly-roll › Concanavalin A-like › Concanavalin A-like lectins/glucanases › Lectin_legB 0.57 51.0 3.71e-01 100.0% 86.8%
4943139 7504.1.1.1 a/b three-layered sandwiches › ITPase-like › ITPase-like › ITPase-like › Ham1p_like 0.57 47.0 3.68e-01 89.9% 75.8%
3303238 10.1.1.11 beta sandwiches › jelly-roll › Concanavalin A-like › Concanavalin A-like lectins/glucanases › Glyco_hydro_16 0.57 42.0 3.79e-01 100.0% 57.5%
4968624 7504.1.1.1 a/b three-layered sandwiches › ITPase-like › ITPase-like › ITPase-like › Ham1p_like 0.57 47.0 3.67e-01 89.9% 77.4%
4992208 2003.1.5.81 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_25 0.56 30.0 2.14e-01 82.0% 18.8%
4135248 10.1.1.4 beta sandwiches › jelly-roll › Concanavalin A-like › Concanavalin A-like lectins/glucanases › Gal-bind_lectin 0.55 49.0 4.34e-01 98.9% 83.1%
3916127 233.1.1.0 a+b two layers › MHC antigen-recognition domain › MHC antigen-recognition domain › MHC antigen-recognition domain 0.55 48.0 3.79e-01 95.5% 87.8%
3690784 10.1.1.22 beta sandwiches › jelly-roll › Concanavalin A-like › Concanavalin A-like lectins/glucanases › DUF1349 0.54 48.0 3.55e-01 100.0% 64.7%
3223910 210.1.2.8 a+b four layers › Ntn/PP2C › Ntn › Penicillin acylase, catalytic domain › TANGO2 0.53 43.0 3.10e-01 89.9% 97.1%
4203230 5.1.3.19 beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 6-bladed › Hira 0.53 49.0 3.76e-01 100.0% 50.3%
3194546 2003.1.1.39 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › Sacchrp_dh_NADP 0.53 43.0 2.75e-01 87.6% 59.5%
5043798 10.1.1.0 beta sandwiches › jelly-roll › Concanavalin A-like › Concanavalin A-like lectins/glucanases 0.52 46.0 3.70e-01 100.0% 64.3%
5026656 7504.1.1.1 a/b three-layered sandwiches › ITPase-like › ITPase-like › ITPase-like › Ham1p_like 0.52 42.0 3.33e-01 89.9% 72.3%
3208973 4099.1.1.4 a+b two layers › Kinetochore globular domain-like › Kinetochore globular domain-like › Kinetochore globular domain-like › CENP-O 0.52 37.0 3.44e-01 88.8% 57.9%
1250267 222.1.1.17 a+b two layers › Thioesterase/thiol ester dehydrase-isomerase-like › Thioesterase/thiol ester dehydrase-isomerase › Thioesterase/thiol ester dehydrase-isomerase › PKS_DH_N 0.52 43.0 3.94e-01 94.4% 88.7%
3974671 243.19.1.0 a+b two layers › Cystatin-like › Phi ETA orf 56-like protein C-terminal domains › Phi ETA orf 56-like protein C-terminal domains 0.52 35.0 3.60e-01 86.5% 72.9%
3905773 233.1.1.1 a+b two layers › MHC antigen-recognition domain › MHC antigen-recognition domain › MHC antigen-recognition domain › MHC_I 0.51 43.0 3.55e-01 98.9% 98.3%
3597025 292.2.1.0 a+b two layers › RIP/Polo-box domain › Polo-box domain › Polo-box domain 0.51 35.0 3.39e-01 100.0% 61.9%
3259637 222.1.1.0 a+b two layers › Thioesterase/thiol ester dehydrase-isomerase-like › Thioesterase/thiol ester dehydrase-isomerase › Thioesterase/thiol ester dehydrase-isomerase 0.50 41.0 3.38e-01 91.0% 65.1%
D4 medium residues 400-466
PDB
Domain cluster: representative
CATH (20)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4r78A02 3.90.1200.10 Alpha Beta › Alpha-Beta Complex › Aminoglycoside 3'-phosphotransferase; Chain: A, domain 2 › Aminoglycoside phosphotransferase (APH), C-terminal lobe 0.67 44.0 3.16e-01 91.0% 24.1%
4djbA00 3.30.70.2870 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Mastadenovirus E4 ORF3 0.66 43.0 3.57e-01 100.0% 38.1%
1hbxA01 3.40.1810.10 Alpha Beta › 3-Layer(aba) Sandwich › SRF-like › Transcription factor, MADS-box 0.63 43.0 4.29e-01 71.6% 70.4%
3duzA03 6.10.250.3010 Special › Helix non-globular › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.63 42.0 4.06e-01 76.1% 61.0%
4oycB00 3.30.300.30 Alpha Beta › 2-Layer Sandwich › GMP Synthetase; Chain A, domain 3 › ANL, C-terminal domain 0.63 43.0 3.86e-01 70.1% 96.6%
2o8bA04 1.10.1420.10 Mainly Alpha › Orthogonal Bundle › MutS, DNA mismatch repair protein; Chain A, domain 3 › 0.62 41.0 3.76e-01 83.6% 54.2%
7wu7501 1.10.287.370 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.62 49.0 4.10e-01 91.0% 65.9%
1c7uA01 3.40.1810.10 Alpha Beta › 3-Layer(aba) Sandwich › SRF-like › Transcription factor, MADS-box 0.60 41.0 4.28e-01 71.6% 77.8%
1xttB00 3.40.50.2020 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.56 38.0 2.66e-01 70.1% 35.6%
1fxkC00 1.10.287.370 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.54 45.0 3.58e-01 91.0% 71.4%
6wqbA01 3.40.630.30 Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Gcn5-related N-acetyltransferase (GNAT) 0.54 39.0 3.13e-01 79.1% 47.3%
1cg2A01 3.40.630.10 Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Zn peptidases 0.54 42.0 2.88e-01 89.6% 93.5%
5ig0A00 3.10.450.50 Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › 0.52 44.0 3.47e-01 91.0% 59.5%
6lw5A01 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.52 43.0 2.84e-01 94.0% 86.4%
1kyzA01 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.52 35.0 3.08e-01 70.1% 97.1%
1vyiA00 1.20.120.820 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Phosphoprotein, C-terminal domain 0.52 39.0 3.28e-01 80.6% 76.6%
2q7eA02 3.30.930.10 Alpha Beta › 2-Layer Sandwich › BirA Bifunctional Protein; domain 2 › Bira Bifunctional Protein; Domain 2 0.52 38.0 2.75e-01 80.6% 59.9%
2mp4A00 3.40.20.10 Alpha Beta › 3-Layer(aba) Sandwich › Severin › Severin 0.51 41.0 3.17e-01 91.0% 64.8%
1bd3A00 3.40.50.2020 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.51 41.0 2.87e-01 89.6% 83.9%
2af6A01 3.30.70.3180 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.50 37.0 2.91e-01 77.6% 52.7%
ECOD (49)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3594109 192.2.1.0 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin 0.75 59.0 4.52e-01 89.6% 38.0%
3989790 3433.1.2.1 a+b duplicates or obligate multimers › ParB dimerization domain › ParB dimerization domain › Chromosome-encoded ParB dimerization domain › ParB_dimer 0.67 31.0 3.55e-01 97.0% 56.0%
4410759 192.2.1.2 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › Prefoldin 0.67 54.0 4.54e-01 88.1% 54.8%
3515407 192.2.1.2 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › Prefoldin 0.67 52.0 3.96e-01 86.6% 45.2%
3238753 192.2.1.2 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › Prefoldin 0.67 52.0 3.89e-01 86.6% 42.9%
3457354 192.2.1.2 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › Prefoldin 0.67 54.0 4.17e-01 88.1% 60.7%
4934732 192.2.1.2 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › Prefoldin 0.66 54.0 4.50e-01 91.0% 69.2%
3229643 192.2.1.2 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › Prefoldin 0.66 53.0 4.36e-01 91.0% 49.2%
4828613 263.1.1.1 a+b three layers › SRF-like › SRF-like › SRF-like › SRF-TF 0.66 44.0 4.15e-01 70.1% 58.0%
3661638 263.1.1.1 a+b three layers › SRF-like › SRF-like › SRF-like › SRF-TF 0.65 45.0 3.96e-01 71.6% 51.6%
3781870 263.1.1.1 a+b three layers › SRF-like › SRF-like › SRF-like › SRF-TF 0.65 45.0 4.10e-01 71.6% 56.5%
3318217 263.1.1.1 a+b three layers › SRF-like › SRF-like › SRF-like › SRF-TF 0.65 44.0 4.19e-01 71.6% 62.5%
6784 263.1.1.1 a+b three layers › SRF-like › SRF-like › SRF-like › SRF-TF 0.64 44.0 4.07e-01 71.6% 58.8%
3491256 192.2.1.2 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › Prefoldin 0.64 50.0 3.74e-01 86.6% 41.7%
4191334 192.2.1.2 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › Prefoldin 0.64 52.0 4.19e-01 91.0% 59.0%
3818050 263.1.1.1 a+b three layers › SRF-like › SRF-like › SRF-like › SRF-TF 0.64 44.0 4.13e-01 71.6% 63.7%
3991902 192.2.1.2 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › Prefoldin 0.63 49.0 4.25e-01 86.6% 69.1%
4029228 192.2.1.2 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › Prefoldin 0.63 48.0 3.58e-01 86.6% 31.1%
4945806 192.2.1.0 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin 0.63 46.0 3.89e-01 83.6% 45.0%
4626792 192.2.1.2 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › Prefoldin 0.62 47.0 3.71e-01 82.1% 42.8%
3215880 601.23.1.4 alpha bundles › Four-helical up-and-down bundle › DNA repair protein MutS, domain III › DNA repair protein MutS, domain III › MutS_IV, MutS_III 0.60 49.0 3.12e-01 89.6% 55.8%
4936526 192.2.1.2 alpha bundles › Long alpha-hairpin › Prefoldin › Prefoldin › Prefoldin 0.60 45.0 3.72e-01 86.6% 42.0%
3801153 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.59 46.0 2.82e-01 83.6% 23.7%
4067342 5069.1.1.15 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › Cytochrom_C_asm 0.58 50.0 3.13e-01 94.0% 39.0%
5077402 2007.15.1.0 a/b three-layered sandwiches › Flavodoxin-like › N-deoxyribosyltransferase › N-deoxyribosyltransferase 0.58 44.0 3.35e-01 88.1% 51.9%
3734132 3542.1.1.3 alpha arrays › Presenilin family intramembrane aspartate proteases › Presenilin family intramembrane aspartate proteases › Presenilin family intramembrane aspartate proteases › Peptidase_A22B 0.57 50.0 3.25e-01 98.5% 64.8%
3627409 6166.1.1.1 alpha bundles › N-terminal domain of Delta(14)-sterol reductase, MaSR1 › N-terminal domain of Delta(14)-sterol reductase, MaSR1 › N-terminal domain of Delta(14)-sterol reductase, MaSR1 › ERG4_ERG24 0.57 39.0 2.79e-01 71.6% 60.5%
4340675 3186.1.1.1 a+b two layers › C-terminal domain of FliK › C-terminal domain of FliK › C-terminal domain of FliK › Flg_hook 0.56 42.0 3.80e-01 80.6% 93.3%
3519143 5001.1.1.0 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like 0.55 46.0 2.97e-01 91.0% 30.8%
4212883 7573.1.1.4 a/b three-layered sandwiches › PRTase-like › PRTase-like › PRTase-like › UPRTase 0.54 37.0 2.59e-01 70.1% 35.1%
4011414 633.23.1.0 alpha bundles › Bromodomain-like › Claudin › Claudin 0.54 45.0 3.07e-01 88.1% 28.4%
3798502 601.23.1.1 alpha bundles › Four-helical up-and-down bundle › DNA repair protein MutS, domain III › DNA repair protein MutS, domain III › MutS_III 0.54 45.0 2.93e-01 92.5% 55.0%
3536880 601.23.1.4 alpha bundles › Four-helical up-and-down bundle › DNA repair protein MutS, domain III › DNA repair protein MutS, domain III › MutS_IV, MutS_III 0.54 44.0 2.84e-01 91.0% 57.8%
3727253 3922.1.1.250 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › ATG14 0.54 47.0 2.94e-01 97.0% 52.5%
3178507 601.23.1.4 alpha bundles › Four-helical up-and-down bundle › DNA repair protein MutS, domain III › DNA repair protein MutS, domain III › MutS_IV, MutS_III 0.54 47.0 2.95e-01 94.0% 57.8%
4033997 4070.1.1.3 alpha arrays › FtsH protease domain-like › FtsH protease domain-like › FtsH protease domain-like › DUF3267 0.53 46.0 3.59e-01 100.0% 98.1%
4026519 3871.1.1.1 alpha duplicates or obligate multimers › PHIST › PHIST › PHIST › PRESAN 0.53 40.0 3.19e-01 98.5% 40.0%
4033043 616.1.1.41 alpha arrays › S15/NS1 RNA-binding domain › S15/NS1 RNA-binding domain › S15/NS1 RNA-binding domain › Terminase_4 0.53 45.0 4.04e-01 91.0% 71.1%
3798149 601.23.1.0 alpha bundles › Four-helical up-and-down bundle › DNA repair protein MutS, domain III › DNA repair protein MutS, domain III 0.53 40.0 2.65e-01 83.6% 65.4%
4002132 5001.1.1.1 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7tm_1 0.52 46.0 2.98e-01 100.0% 84.0%
4489568 140.1.1.21 alpha bundles › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › tRNA-synt_1e, CysS_C 0.52 40.0 2.89e-01 85.1% 46.5%
3789210 601.23.1.1 alpha bundles › Four-helical up-and-down bundle › DNA repair protein MutS, domain III › DNA repair protein MutS, domain III › MutS_III 0.52 45.0 2.90e-01 97.0% 57.2%
4816472 5073.1.1.0 alpha bundles › Calcium ATPase transmembrane domain-related › Calcium ATPase transmembrane domain-related › Calcium ATPase transmembrane domain M 0.51 37.0 3.10e-01 94.0% 44.1%
4028937 109.4.1.1255 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Adaptin_N, Cnd1 0.51 41.0 2.34e-01 94.0% 7.9%
3632622 320.1.1.0 a+b two layers › R3H domain-like › R3H domain › R3H domain 0.51 39.0 3.37e-01 85.1% 93.6%
3425722 386.1.1.117 few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › DUF7028 0.51 37.0 3.38e-01 76.1% 90.6%
3218266 5001.1.1.41 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Srw 0.51 45.0 2.83e-01 100.0% 25.1%
3719707 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.51 41.0 2.76e-01 88.1% 25.3%
3620976 10.4.1.0 beta sandwiches › jelly-roll › Spermadhesin, CUB domain › Spermadhesin, CUB domain 0.50 36.0 2.55e-01 94.0% 23.7%