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IMGVR_UViG_2875952388_000001-2875952388-2875952416
Arc-VirIMGVR_UViG_2875952388_000001-2875952388-2875952416
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 308-422
Domain cluster:
rep: IMGVR_UViG_3300009360_000161-3300009360-Ga0118672_100139611__D314-428
CATH (6)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4asvA00 | 1.20.5.420 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › Immunoglobulin FC, subunit C | 0.55 | 34.0 | 3.96e-01 | 77.4% | 89.9% |
| 2prrA02 | 1.20.1290.10 | Mainly Alpha › Up-down Bundle › AhpD-like › AhpD-like | 0.53 | 38.0 | 3.74e-01 | 74.8% | 78.0% |
| 2o3fA00 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.52 | 33.0 | 3.80e-01 | 97.4% | 87.8% |
| 4iluA02 | 1.20.58.1290 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › CarD-like, C-terminal domain | 0.51 | 35.0 | 3.59e-01 | 80.9% | 72.1% |
| 3p7nA02 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.51 | 28.0 | 3.47e-01 | 77.4% | 86.1% |
| 2pbiA02 | 1.10.1240.60 | Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › | 0.50 | 35.0 | 3.70e-01 | 75.7% | 81.2% |
ECOD (10)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4942022 | 182.1.3.3 ↗ | alpha complex topology › Cryptochrome/photolyase FAD-binding domain-related › Cryptochrome/photolyase FAD-binding domain-related › PriX › DNA_primase_lrg | 0.84 | 71.0 | 7.06e-01 | 100.0% | 85.0% |
| 5030284 | 182.1.3.3 ↗ | alpha complex topology › Cryptochrome/photolyase FAD-binding domain-related › Cryptochrome/photolyase FAD-binding domain-related › PriX › DNA_primase_lrg | 0.77 | 70.0 | 6.94e-01 | 100.0% | 92.5% |
| 5081313 | 182.1.3.0 ↗ | alpha complex topology › Cryptochrome/photolyase FAD-binding domain-related › Cryptochrome/photolyase FAD-binding domain-related › PriX | 0.76 | 57.0 | 6.41e-01 | 93.9% | 100.0% |
| 5064030 | 182.1.3.0 ↗ | alpha complex topology › Cryptochrome/photolyase FAD-binding domain-related › Cryptochrome/photolyase FAD-binding domain-related › PriX | 0.75 | 58.0 | 6.31e-01 | 92.2% | 98.9% |
| 3586830 | 182.1.3.2 ↗ | alpha complex topology › Cryptochrome/photolyase FAD-binding domain-related › Cryptochrome/photolyase FAD-binding domain-related › PriX › PriCT_1 | 0.71 | 63.0 | 6.39e-01 | 98.3% | 94.8% |
| 4984330 | 3651.1.1.0 ↗ | alpha bundles › Translation initiation factor eIF-2B delta subunit N-terminal helical domain › Translation initiation factor eIF-2B delta subunit N-terminal helical domain › Translation initiation factor eIF-2B delta subunit N-terminal helical domain | 0.63 | 47.0 | 5.24e-01 | 80.0% | 98.9% |
| 4071151 | 3651.1.1.0 ↗ | alpha bundles › Translation initiation factor eIF-2B delta subunit N-terminal helical domain › Translation initiation factor eIF-2B delta subunit N-terminal helical domain › Translation initiation factor eIF-2B delta subunit N-terminal helical domain | 0.63 | 49.0 | 4.70e-01 | 81.7% | 83.8% |
| 3628756 | 601.1.1.60 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › Death_MADD | 0.59 | 48.0 | 5.13e-01 | 85.2% | 99.0% |
| 3289143 | 101.1.3.1 ↗ | alpha arrays › HTH › HTH › tetra-helical, LuxR-like › GerE | 0.53 | 29.0 | 3.32e-01 | 80.9% | 70.6% |
| 3313196 | 101.1.1.3 ↗ | alpha arrays › HTH › HTH › Three-helical HTH › Myb_DNA-binding | 0.52 | 36.0 | 3.55e-01 | 72.2% | 77.6% |
D2
high
residues 585-780
Domain cluster:
rep: MN062720.1__QDP45567.1__SEA_FUZZBUSTER_83__00083__D568-722_747-764
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF19263.6 best | DUF5906 | 53.5 | 5.20e-14 | 58.2% | 94.7% |
D3
high
residues 785-870_890-914
Domain cluster:
representative
CATH (3)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2dqlA00 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.52 | 41.0 | 4.12e-01 | 100.0% | 81.7% |
| 1vx4407 | 3.30.70.240 | Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › | 0.50 | 29.0 | 3.46e-01 | 84.7% | 88.4% |
| 3nqoB00 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.50 | 39.0 | 3.43e-01 | 85.6% | 65.0% |
ECOD (15)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5029778 | 101.1.2.43 ↗ | alpha arrays › HTH › HTH › winged helix domain › Pox_D5 | 0.89 | 68.0 | 7.63e-01 | 100.0% | 97.8% |
| 5003621 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.87 | 69.0 | 7.44e-01 | 97.3% | 95.8% |
| 3537242 | 101.1.2.34 ↗ | alpha arrays › HTH › HTH › winged helix domain › RFX_DNA_binding | 0.84 | 58.0 | 6.11e-01 | 70.3% | 80.0% |
| 3898745 | 101.1.2.34 ↗ | alpha arrays › HTH › HTH › winged helix domain › RFX_DNA_binding | 0.84 | 58.0 | 6.22e-01 | 70.3% | 87.4% |
| 5022021 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.84 | 64.0 | 6.32e-01 | 100.0% | 75.7% |
| 3883278 | 101.1.2.34 ↗ | alpha arrays › HTH › HTH › winged helix domain › RFX_DNA_binding | 0.82 | 62.0 | 6.64e-01 | 89.2% | 90.5% |
| 3177239 | 101.1.2.34 ↗ | alpha arrays › HTH › HTH › winged helix domain › RFX_DNA_binding | 0.82 | 56.0 | 5.18e-01 | 70.3% | 57.0% |
| 3689786 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.70 | 57.0 | 4.85e-01 | 84.7% | 65.9% |
| 5025840 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.63 | 43.0 | 4.55e-01 | 70.3% | 83.0% |
| 3289681 | 101.1.2.48 ↗ | alpha arrays › HTH › HTH › winged helix domain › PadR | 0.62 | 42.0 | 3.54e-01 | 70.3% | 54.9% |
| 5001284 | 101.1.2.48 ↗ | alpha arrays › HTH › HTH › winged helix domain › PadR | 0.61 | 42.0 | 3.70e-01 | 70.3% | 76.2% |
| 3206556 | 101.1.2.24 ↗ | alpha arrays › HTH › HTH › winged helix domain › MAGE | 0.55 | 38.0 | 2.98e-01 | 71.2% | 37.6% |
| 5023057 | 304.126.1.0 ↗ | a+b two layers › Alpha-beta plaits › ferredoxin-like domain in vacuolar ATP synthase subunit C › ferredoxin-like domain in vacuolar ATP synthase subunit C | 0.52 | 29.0 | 3.30e-01 | 82.9% | 74.7% |
| 5071269 | 101.1.2.48 ↗ | alpha arrays › HTH › HTH › winged helix domain › PadR | 0.52 | 46.0 | 3.79e-01 | 100.0% | 80.5% |
| 4991130 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.50 | 40.0 | 3.87e-01 | 87.4% | 93.8% |
D4
medium
residues 1-107_144-167
Domain cluster:
representative
D5
medium
residues 108-143_168-222_264-290
Domain cluster:
representative
CATH (1)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5z7cA01 | 1.10.3210.10 | Mainly Alpha › Orthogonal Bundle › Hypothetical protein af1432 › Hypothetical protein af1432 | 0.53 | 40.0 | 3.56e-01 | 81.4% | 63.1% |
ECOD (1)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3580795 | 140.1.1.0 ↗ | alpha bundles › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 0.59 | 41.0 | 3.71e-01 | 72.0% | 57.5% |
D6
medium
residues 435-518
Domain cluster:
rep: IMGVR_UViG_3300009362_000174-3300009362-Ga0118673_10090134__D7-95
CATH (20)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3e3vA03 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.74 | 48.0 | 5.67e-01 | 81.0% | 100.0% |
| 3e3vA01 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.73 | 45.0 | 5.40e-01 | 83.3% | 98.1% |
| 2x48A00 | 1.10.10.60 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like | 0.70 | 34.0 | 4.12e-01 | 70.2% | 70.4% |
| 2b8iA00 | 1.20.1280.100 | Mainly Alpha › Up-down Bundle › Monooxygenase › Pas factor, saposin domain | 0.59 | 40.0 | 4.13e-01 | 95.2% | 75.3% |
| 2kw3C00 | 6.10.290.30 | Special › Helix non-globular › Four Helix Bundle (Hemerythrin (Met), subunit A) › Regulatory factor X-associated C-terminal binding domain | 0.59 | 35.0 | 3.97e-01 | 75.0% | 79.0% |
| 3ajvC02 | 3.40.1350.10 | Alpha Beta › 3-Layer(aba) Sandwich › Trna Endonuclease; Chain: A, domain 1 › | 0.58 | 32.0 | 3.12e-01 | 79.8% | 48.4% |
| 3onqA01 | 1.20.5.5100 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › | 0.56 | 29.0 | 3.86e-01 | 78.6% | 100.0% |
| 1kaeA03 | 1.20.5.1300 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › | 0.56 | 28.0 | 3.37e-01 | 91.7% | 72.7% |
| 1gzsB00 | 1.10.4120.10 | Mainly Alpha › Orthogonal Bundle › SopE-like GEF fold › SopE-like, GEF domain | 0.55 | 48.0 | 3.94e-01 | 100.0% | 84.2% |
| 1vq0A02 | 3.90.1280.10 | Alpha Beta › Alpha-Beta Complex › CBS domain Like › HSP33 redox switch-like | 0.54 | 34.0 | 3.98e-01 | 91.7% | 96.5% |
| 3hlbD00 | 3.40.710.10 | Alpha Beta › 3-Layer(aba) Sandwich › Beta-lactamase › DD-peptidase/beta-lactamase superfamily | 0.53 | 41.0 | 2.71e-01 | 85.7% | 63.4% |
| 1f2uB00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.53 | 34.0 | 2.88e-01 | 72.6% | 37.9% |
| 1te2A02 | 1.10.150.240 | Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 | 0.53 | 36.0 | 3.87e-01 | 86.9% | 81.9% |
| 4pdyA02 | 3.90.1200.10 | Alpha Beta › Alpha-Beta Complex › Aminoglycoside 3'-phosphotransferase; Chain: A, domain 2 › Aminoglycoside phosphotransferase (APH), C-terminal lobe | 0.53 | 45.0 | 3.38e-01 | 98.8% | 83.3% |
| 5y6qB02 | 3.30.390.50 | Alpha Beta › 2-Layer Sandwich › Enolase-like; domain 1 › CO dehydrogenase flavoprotein, C-terminal domain | 0.52 | 38.0 | 3.56e-01 | 86.9% | 61.3% |
| 3hkoA02 | 1.10.510.10 | Mainly Alpha › Orthogonal Bundle › Transferase(Phosphotransferase); domain 1 › Transferase(Phosphotransferase) domain 1 | 0.51 | 39.0 | 2.97e-01 | 84.5% | 70.4% |
| 5mdtA00 | 1.25.40.90 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › | 0.51 | 41.0 | 3.48e-01 | 90.5% | 50.0% |
| 4g09A03 | 1.20.5.1300 | Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › | 0.51 | 26.0 | 3.07e-01 | 79.8% | 70.9% |
| 3ikhA00 | 3.40.1190.20 | Alpha Beta › 3-Layer(aba) Sandwich › UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase › Ribokinase | 0.51 | 37.0 | 2.56e-01 | 75.0% | 78.3% |
| 1rypK00 | 3.60.20.10 | Alpha Beta › 4-Layer Sandwich › Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1 › Aminohydrolase, N-terminal nucleophile (Ntn) domain | 0.50 | 39.0 | 3.04e-01 | 85.7% | 71.7% |
ECOD (20)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 5003620 | 2004.1.1.409 ↗ | a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › DUF5906 | 0.91 | 83.0 | 5.32e-01 | 100.0% | 24.2% |
| 3326759 | 284.1.3.1 ↗ | a+b two layers › FKBP-like › FKBP-like › WNK1 autoinhibitory domain › SNF5 | 0.68 | 45.0 | 4.72e-01 | 90.5% | 76.0% |
| 4001707 | 284.1.3.0 ↗ | a+b two layers › FKBP-like › FKBP-like › WNK1 autoinhibitory domain | 0.62 | 45.0 | 4.52e-01 | 98.8% | 76.5% |
| 3680302 | 6113.1.1.0 ↗ | alpha duplicates or obligate multimers › Dimerization element domain in modular polyketide synthases › Dimerization element domain in modular polyketide synthases › Dimerization element domain in modular polyketide synthases | 0.62 | 33.0 | 3.48e-01 | 94.0% | 56.0% |
| 3472467 | 284.1.3.0 ↗ | a+b two layers › FKBP-like › FKBP-like › WNK1 autoinhibitory domain | 0.61 | 38.0 | 3.99e-01 | 91.7% | 69.3% |
| 5024884 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.61 | 46.0 | 4.67e-01 | 84.5% | 82.4% |
| 3361 | 107.1.1.6 ↗ | alpha arrays › Cytochrome c-like › Cytochrome c › Cytochrome c › Dehyd-heme_bind | 0.59 | 45.0 | 4.58e-01 | 86.9% | 82.1% |
| 3238459 | 616.1.1.0 ↗ | alpha arrays › S15/NS1 RNA-binding domain › S15/NS1 RNA-binding domain › S15/NS1 RNA-binding domain | 0.57 | 29.0 | 3.27e-01 | 77.4% | 61.5% |
| 3369751 | 101.1.2.245 ↗ | alpha arrays › HTH › HTH › winged helix domain › PORR | 0.54 | 39.0 | 2.67e-01 | 98.8% | 20.3% |
| 3692667 | 5.1.4.223 ↗ | beta duplicates or obligate multimers › beta-propeller-like › beta-propeller › 7-bladed › Beta-prop_RIC1_2nd | 0.53 | 36.0 | 2.33e-01 | 71.4% | 20.7% |
| 4940842 | 304.28.1.38 ↗ | a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain › CAA_C | 0.53 | 39.0 | 3.05e-01 | 78.6% | 73.5% |
| 4867395 | 3820.1.1.1 ↗ | a+b complex topology › CRISPR-associated endonuclease Cas9 C-terminal domain › CRISPR-associated endonuclease Cas9 C-terminal domain › CRISPR-associated endonuclease Cas9 C-terminal domain › Cas9_PI | 0.52 | 42.0 | 3.42e-01 | 88.1% | 61.1% |
| 4996608 | 2007.9.1.4 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Toll/Interleukin receptor TIR domain › Toll/Interleukin receptor TIR domain › TIR_2 | 0.52 | 32.0 | 2.52e-01 | 92.9% | 26.0% |
| 5016556 | 4.1.1.0 ↗ | beta barrels › SH3 › SH3 › SH3 | 0.52 | 31.0 | 3.11e-01 | 100.0% | 55.6% |
| 5016114 | 2007.1.14.32 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Chelatase-like › 2-thiour_desulf | 0.52 | 42.0 | 3.44e-01 | 92.9% | 68.2% |
| 4951908 | 2007.1.14.32 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Chelatase-like › 2-thiour_desulf | 0.51 | 40.0 | 2.99e-01 | 88.1% | 48.1% |
| 3616581 | 7512.1.1.6 ↗ | a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glyco_transf_20 | 0.51 | 39.0 | 2.71e-01 | 85.7% | 65.1% |
| 4027206 | 101.1.2.0 ↗ | alpha arrays › HTH › HTH › winged helix domain | 0.51 | 42.0 | 3.67e-01 | 96.4% | 67.9% |
| 4020842 | 3209.1.1.0 ↗ | a+b two layers › RPL28 › RPL28 › RPL28 | 0.50 | 42.0 | 3.66e-01 | 96.4% | 87.9% |
| 3629581 | 7512.1.1.6 ↗ | a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glyco_transf_20 | 0.50 | 41.0 | 2.86e-01 | 90.5% | 57.5% |