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IMGVR_UViG_2904991991_000001-2904991991-2904995957

Arc-Vir

IMGVR_UViG_2904991991_000001-2904991991-2904995957

Identity

Kingdom:
archaea

Quality

73.9 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 464-595
PDB
CATH (19)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3vgpA00 3.40.50.12610 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.67 61.0 5.72e-01 100.0% 96.3%
3l8dA00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.61 54.0 4.73e-01 100.0% 98.0%
3hnrA00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.58 52.0 4.62e-01 100.0% 94.3%
8k1fC01 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.58 51.0 4.54e-01 100.0% 87.8%
2hnkA00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.57 51.0 4.31e-01 100.0% 81.7%
4ymhD00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.57 50.0 4.23e-01 100.0% 79.1%
2rbkA02 3.30.1240.10 Alpha Beta › 2-Layer Sandwich › Hypothetical Protein, Haloacid Dehalogenase-like Hydrolase; Chain: A; domain 2 › 0.55 33.0 3.70e-01 88.6% 76.2%
2grvA01 3.40.190.10 Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › Periplasmic binding protein-like II 0.55 45.0 4.11e-01 87.1% 83.9%
4xpkA00 3.40.630.30 Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Gcn5-related N-acetyltransferase (GNAT) 0.55 32.0 3.13e-01 87.1% 51.8%
4p72A04 3.30.56.10 Alpha Beta › 2-Layer Sandwich › Phenylalanyl-tRNA Synthetase; Chain B, domain 1 › 0.55 23.0 2.94e-01 86.4% 63.2%
1nv8A02 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.55 49.0 4.33e-01 100.0% 90.4%
3pgvA02 3.30.1240.10 Alpha Beta › 2-Layer Sandwich › Hypothetical Protein, Haloacid Dehalogenase-like Hydrolase; Chain: A; domain 2 › 0.54 33.0 3.63e-01 87.9% 75.2%
2zzzA02 3.30.63.10 Alpha Beta › 2-Layer Sandwich › Guanylate Kinase phosphate binding domain › Guanylate Kinase phosphate binding domain 0.53 23.0 3.12e-01 84.8% 81.7%
3r4cA02 3.30.1240.10 Alpha Beta › 2-Layer Sandwich › Hypothetical Protein, Haloacid Dehalogenase-like Hydrolase; Chain: A; domain 2 › 0.53 32.0 3.54e-01 88.6% 76.2%
2c4nA02 3.40.50.1000 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HAD superfamily/HAD-like 0.52 39.0 4.20e-01 91.7% 100.0%
2pq0A02 3.30.1240.10 Alpha Beta › 2-Layer Sandwich › Hypothetical Protein, Haloacid Dehalogenase-like Hydrolase; Chain: A; domain 2 › 0.51 31.0 3.43e-01 88.6% 76.0%
2o20A02 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.50 44.0 4.44e-01 100.0% 99.3%
5yszA03 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.50 44.0 4.42e-01 100.0% 100.0%
2pjdA01 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.50 45.0 4.27e-01 100.0% 91.7%
ECOD (49)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4960587 3110.1.1.0 a/b three-layered sandwiches › STT3/PglB/AglB core domain › STT3/PglB/AglB core domain › STT3/PglB/AglB core domain 0.88 71.0 7.74e-01 99.2% 99.1%
4962004 3110.1.1.0 a/b three-layered sandwiches › STT3/PglB/AglB core domain › STT3/PglB/AglB core domain › STT3/PglB/AglB core domain 0.84 69.0 7.32e-01 100.0% 98.3%
4997021 3110.1.1.0 a/b three-layered sandwiches › STT3/PglB/AglB core domain › STT3/PglB/AglB core domain › STT3/PglB/AglB core domain 0.77 56.0 6.37e-01 100.0% 99.0%
5027907 3110.1.1.0 a/b three-layered sandwiches › STT3/PglB/AglB core domain › STT3/PglB/AglB core domain › STT3/PglB/AglB core domain 0.73 56.0 6.04e-01 100.0% 92.2%
4994945 3110.1.1.0 a/b three-layered sandwiches › STT3/PglB/AglB core domain › STT3/PglB/AglB core domain › STT3/PglB/AglB core domain 0.73 65.0 6.27e-01 100.0% 85.5%
5053758 3110.1.1.0 a/b three-layered sandwiches › STT3/PglB/AglB core domain › STT3/PglB/AglB core domain › STT3/PglB/AglB core domain 0.71 66.0 6.44e-01 100.0% 97.2%
4952082 3110.1.1.0 a/b three-layered sandwiches › STT3/PglB/AglB core domain › STT3/PglB/AglB core domain › STT3/PglB/AglB core domain 0.69 61.0 6.21e-01 100.0% 96.9%
5019362 3110.1.1.0 a/b three-layered sandwiches › STT3/PglB/AglB core domain › STT3/PglB/AglB core domain › STT3/PglB/AglB core domain 0.68 54.0 5.90e-01 98.5% 100.0%
4996461 3110.1.1.0 a/b three-layered sandwiches › STT3/PglB/AglB core domain › STT3/PglB/AglB core domain › STT3/PglB/AglB core domain 0.68 60.0 6.08e-01 100.0% 95.4%
5029352 3110.1.1.0 a/b three-layered sandwiches › STT3/PglB/AglB core domain › STT3/PglB/AglB core domain › STT3/PglB/AglB core domain 0.68 59.0 6.11e-01 97.7% 98.4%
5029823 3110.1.1.2 a/b three-layered sandwiches › STT3/PglB/AglB core domain › STT3/PglB/AglB core domain › STT3/PglB/AglB core domain › STT3-PglB_core 0.66 61.0 5.55e-01 100.0% 88.0%
5025617 3110.1.1.0 a/b three-layered sandwiches › STT3/PglB/AglB core domain › STT3/PglB/AglB core domain › STT3/PglB/AglB core domain 0.66 62.0 5.59e-01 100.0% 77.1%
4998197 3110.1.1.0 a/b three-layered sandwiches › STT3/PglB/AglB core domain › STT3/PglB/AglB core domain › STT3/PglB/AglB core domain 0.66 59.0 5.92e-01 95.5% 98.5%
5056132 3110.1.1.0 a/b three-layered sandwiches › STT3/PglB/AglB core domain › STT3/PglB/AglB core domain › STT3/PglB/AglB core domain 0.66 60.0 5.99e-01 100.0% 96.2%
5013901 3110.1.1.0 a/b three-layered sandwiches › STT3/PglB/AglB core domain › STT3/PglB/AglB core domain › STT3/PglB/AglB core domain 0.65 59.0 5.99e-01 97.0% 98.5%
5009886 3110.1.1.0 a/b three-layered sandwiches › STT3/PglB/AglB core domain › STT3/PglB/AglB core domain › STT3/PglB/AglB core domain 0.64 58.0 5.66e-01 99.2% 99.3%
4979496 328.9.1.0 a+b two layers › IF3-like › SepF C-terminal domain › SepF C-terminal domain 0.61 32.0 4.23e-01 84.8% 100.0%
5023636 3110.1.1.21 a/b three-layered sandwiches › STT3/PglB/AglB core domain › STT3/PglB/AglB core domain › STT3/PglB/AglB core domain › PF29526 0.61 53.0 5.52e-01 100.0% 99.2%
5027697 3110.1.1.0 a/b three-layered sandwiches › STT3/PglB/AglB core domain › STT3/PglB/AglB core domain › STT3/PglB/AglB core domain 0.60 51.0 5.23e-01 100.0% 95.2%
4942126 328.9.1.0 a+b two layers › IF3-like › SepF C-terminal domain › SepF C-terminal domain 0.60 31.0 4.20e-01 85.6% 95.7%
4933974 328.9.1.0 a+b two layers › IF3-like › SepF C-terminal domain › SepF C-terminal domain 0.60 31.0 4.14e-01 84.1% 100.0%
3989781 3110.1.1.18 a/b three-layered sandwiches › STT3/PglB/AglB core domain › STT3/PglB/AglB core domain › STT3/PglB/AglB core domain › PF29470 0.59 46.0 4.88e-01 100.0% 95.6%
5057825 328.1.1.0 a+b two layers › IF3-like › AlbA-like › AlbA-like 0.59 32.0 4.04e-01 85.6% 92.0%
4224634 2003.1.5.81 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_25 0.59 53.0 4.56e-01 100.0% 92.8%
4988836 2003.1.5.66 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_11 0.59 52.0 5.02e-01 100.0% 97.4%
3954670 2003.1.5.66 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_11 0.59 51.0 4.52e-01 98.5% 86.0%
4974442 328.1.1.0 a+b two layers › IF3-like › AlbA-like › AlbA-like 0.58 32.0 3.99e-01 85.6% 92.0%
5053540 2003.1.5.67 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_12 0.58 52.0 4.41e-01 100.0% 92.9%
4629764 2003.1.5.81 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_25 0.58 52.0 4.48e-01 100.0% 87.6%
4132371 2003.1.5.152 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › CMAS, Methyltransf_25 0.58 52.0 4.49e-01 100.0% 91.0%
3948498 7523.1.1.3 a/b three-layered sandwiches › Periplasmic binding protein-like II › Periplasmic binding protein-like II › Periplasmic binding protein-like II › SBP_bac_5 0.58 47.0 4.33e-01 87.9% 82.9%
4964276 2003.1.5.81 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_25 0.58 51.0 4.52e-01 100.0% 87.5%
4044555 2003.1.5.151 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_23, Methyltransf_25 0.58 51.0 4.48e-01 100.0% 93.2%
3822416 101.1.2.7 alpha arrays › HTH › HTH › winged helix domain › HSF_DNA-bind 0.58 31.0 3.45e-01 83.3% 64.8%
5055619 3110.1.1.21 a/b three-layered sandwiches › STT3/PglB/AglB core domain › STT3/PglB/AglB core domain › STT3/PglB/AglB core domain › PF29526 0.57 53.0 5.08e-01 100.0% 92.0%
4999706 2003.1.5.66 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_11 0.57 50.0 4.18e-01 100.0% 77.1%
5026207 2003.1.5.67 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_12 0.57 50.0 4.63e-01 100.0% 96.0%
4215092 3012.1.1.4 a+b two layers › Cof C2 cap domain › Cof C2 cap domain › Cof C2 cap domain › Hydrolase_3 0.56 40.0 4.13e-01 91.7% 80.0%
3234681 2003.1.5.14 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_3 0.56 50.0 4.05e-01 100.0% 70.7%
5013441 2003.1.5.66 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_11 0.55 49.0 4.33e-01 100.0% 86.0%
5076758 328.9.1.0 a+b two layers › IF3-like › SepF C-terminal domain › SepF C-terminal domain 0.55 30.0 3.78e-01 84.8% 92.0%
3166251 7523.1.1.3 a/b three-layered sandwiches › Periplasmic binding protein-like II › Periplasmic binding protein-like II › Periplasmic binding protein-like II › SBP_bac_5 0.55 44.0 4.14e-01 86.4% 86.7%
3367254 2003.1.5.154 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_29, Methyltransf_11 0.54 48.0 3.17e-01 100.0% 31.5%
5001223 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.53 45.0 3.67e-01 92.4% 85.5%
4935902 247.1.1.1 a+b four layers › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Metallo-hydrolase/oxidoreductase › Lactamase_B 0.52 38.0 3.20e-01 75.0% 80.0%
4988179 327.11.2.0 a+b two layers › Alpha-lytic protease prodomain-like › KH-domains › Eukaryotic type KH-domain (KH-domain type I) 0.52 21.0 2.83e-01 91.7% 68.8%
4643722 101.1.9.16 alpha arrays › HTH › HTH › Putative DNA-binding domain › HTH_17 0.52 21.0 3.04e-01 90.9% 90.0%
4510425 2004.1.1.50 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Guanylate_kin 0.51 40.0 3.68e-01 85.6% 95.0%
3735781 101.1.2.288 alpha arrays › HTH › HTH › winged helix domain › Stk19 0.50 39.0 3.54e-01 84.8% 97.3%
D2 medium residues 1-102
PDB
Domain cluster: representative
CATH (80)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2l6jA00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.79 50.0 4.87e-01 93.1% 59.5%
1hs7A00 1.20.58.70 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.75 63.0 6.43e-01 93.1% 94.8%
1t98A02 1.20.58.590 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Chromosome partition protein MukF, middle domain 0.73 62.0 5.27e-01 91.2% 93.3%
2lw1A00 1.10.287.380 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Valyl-tRNA synthetase, C-terminal domain 0.73 46.0 4.97e-01 71.6% 75.3%
2dnxA00 1.20.58.70 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.72 65.0 6.04e-01 100.0% 90.0%
2l3lA01 1.20.58.1250 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Tubulin Binding Cofactor C, N-terminal domain 0.72 55.0 5.45e-01 97.1% 78.3%
2vxxA00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.71 58.0 4.85e-01 88.2% 84.9%
3kmiA00 1.20.120.940 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Putative aromatic acid exporter, C-terminal domain 0.70 60.0 5.00e-01 92.2% 89.5%
4oydB00 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.70 60.0 5.80e-01 94.1% 99.1%
1m56C02 1.20.120.80 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Cytochrome c oxidase, subunit III, four-helix bundle 0.69 56.0 4.51e-01 87.3% 95.9%
2fjcB00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.69 56.0 4.90e-01 89.2% 92.3%
7f16R01 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.68 51.0 3.69e-01 78.4% 72.6%
2o36A01 1.20.1050.40 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › Endopeptidase. Chain P; domain 1 0.68 59.0 5.47e-01 95.1% 96.9%
3t6gB00 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.68 59.0 5.43e-01 96.1% 73.9%
2e9xA01 1.20.58.1030 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.68 54.0 4.97e-01 84.3% 68.8%
5wp3B00 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.68 58.0 5.82e-01 93.1% 100.0%
3m0fB02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.67 55.0 5.18e-01 87.3% 74.8%
1wrdA00 1.20.58.160 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.67 59.0 6.01e-01 98.0% 100.0%
3axjB01 1.20.58.190 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 1 0.67 59.0 5.12e-01 97.1% 65.8%
5u1aL00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.66 56.0 4.81e-01 93.1% 97.0%
5z7qA00 1.20.1330.10 Mainly Alpha › Up-down Bundle › f41 fragment of flagellin, N-terminal domain › f41 fragment of flagellin, N-terminal domain 0.66 57.0 4.78e-01 95.1% 66.5%
3hiuD00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.66 56.0 4.90e-01 92.2% 93.4%
1j30A00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.66 50.0 4.43e-01 78.4% 61.0%
1br0A00 1.20.58.70 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.66 58.0 5.51e-01 97.1% 99.2%
2qvaA01 1.20.58.190 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Translin; domain 1 0.66 55.0 5.15e-01 97.1% 73.6%
2crbA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.65 48.0 4.95e-01 92.2% 82.5%
2qgmA03 1.20.1440.30 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › Biosynthetic Protein domain 0.65 45.0 4.38e-01 89.2% 62.9%
1q16C01 1.20.950.20 Mainly Alpha › Up-down Bundle › Fumarate Reductase Cytochrome B subunit › Transmembrane di-heme cytochromes, Chain C 0.65 56.0 4.42e-01 94.1% 62.6%
3ajmB02 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.65 52.0 4.84e-01 94.1% 67.7%
1io1A01 1.20.1330.10 Mainly Alpha › Up-down Bundle › f41 fragment of flagellin, N-terminal domain › f41 fragment of flagellin, N-terminal domain 0.65 55.0 4.64e-01 92.2% 66.3%
2c41C01 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.65 57.0 5.05e-01 98.0% 100.0%
2ykgA03 1.20.1320.30 Mainly Alpha › Up-down Bundle › phosphoenolpyruvate carboxylase, domain 3 › 0.65 42.0 3.88e-01 89.2% 50.4%
4id0A02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.65 52.0 5.04e-01 87.3% 78.6%
4mk3A02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.64 52.0 5.03e-01 87.3% 79.1%
2gs4A00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.64 56.0 4.89e-01 98.0% 99.4%
6xz3A01 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.64 51.0 4.93e-01 87.3% 75.2%
2nwbA02 1.20.58.480 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.64 57.0 4.37e-01 99.0% 69.2%
3fseB02 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.64 56.0 5.00e-01 96.1% 97.9%
3vprA02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.64 55.0 4.91e-01 95.1% 66.2%
3pwfA01 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.64 43.0 4.00e-01 78.4% 54.2%
1lkoA01 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.63 54.0 4.89e-01 96.1% 97.9%
1z23A00 1.20.120.830 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Serine-rich domain 0.63 55.0 4.74e-01 96.1% 77.9%
4djhA01 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.63 50.0 3.70e-01 87.3% 76.0%
2imiB02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.63 54.0 4.87e-01 94.1% 91.4%
1nfvA00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.63 54.0 4.60e-01 95.1% 87.6%
7wujE01 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.62 48.0 3.61e-01 83.3% 72.5%
2yayA02 1.20.1670.10 Mainly Alpha › Up-down Bundle › all-alpha NTP pyrophosphatase › Type II deoxyuridine triphosphatase 0.62 50.0 4.56e-01 86.3% 99.3%
3rx6A00 1.20.58.1090 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phage polarity suppression protein monomer 0.62 48.0 3.98e-01 83.3% 87.2%
1zs3A00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.62 54.0 4.58e-01 96.1% 87.7%
3gi8C00 1.20.1740.10 Mainly Alpha › Up-down Bundle › Amino acid/polyamine transporter I › Amino acid/polyamine transporter I 0.62 49.0 3.24e-01 85.3% 58.6%
2chpA00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.62 55.0 4.85e-01 98.0% 100.0%
1oxjA02 1.25.40.170 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Smaug, PHAT domain 0.62 45.0 4.47e-01 86.3% 71.6%
2fzfA01 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.62 53.0 4.73e-01 96.1% 97.3%
4rngC00 1.20.1280.290 Mainly Alpha › Up-down Bundle › Monooxygenase › 0.62 47.0 5.15e-01 93.1% 100.0%
2ib0A01 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.62 53.0 4.89e-01 96.1% 100.0%
1nlxA00 1.20.120.320 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Group V grass pollen allergen 0.62 44.0 4.39e-01 90.2% 73.1%
4ikhA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.61 50.0 4.69e-01 89.2% 71.7%
3ppuB02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.61 49.0 4.76e-01 88.2% 77.0%
3r2qA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.61 48.0 4.69e-01 86.3% 77.0%
7xxiA01 1.20.1070.10 Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins 0.61 49.0 3.60e-01 88.2% 78.6%
7dwqL01 1.20.1240.10 Mainly Alpha › Up-down Bundle › Photosystem 1 Reaction Centre Subunit Xi; Chain: L; › Photosystem I PsaL, reaction centre subunit XI 0.61 47.0 4.44e-01 83.3% 81.6%
2va8A03 1.10.3380.30 Mainly Alpha › Orthogonal Bundle › Sec63 N-terminal domain-like fold › 0.61 51.0 3.94e-01 91.2% 77.9%
1zymA02 1.10.274.10 Mainly Alpha › Orthogonal Bundle › Enzyme I; Chain A, domain 2 › PtsI, HPr-binding domain 0.60 43.0 4.05e-01 81.4% 60.3%
5ux2B01 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.60 53.0 4.18e-01 98.0% 68.7%
3ay8A02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.60 50.0 4.61e-01 94.1% 94.1%
2ondA00 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.59 52.0 3.66e-01 95.1% 34.1%
2qf9A01 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.59 50.0 4.42e-01 95.1% 98.7%
7c1iA01 1.20.120.160 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain 0.59 42.0 4.23e-01 94.1% 74.0%
3u3iA02 1.20.58.1110 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.59 47.0 4.65e-01 85.3% 82.4%
2hroA02 1.10.274.10 Mainly Alpha › Orthogonal Bundle › Enzyme I; Chain A, domain 2 › PtsI, HPr-binding domain 0.59 42.0 3.94e-01 86.3% 59.4%
1kz7A01 1.20.900.10 Mainly Alpha › Up-down Bundle › Dbl Homology Domain; Chain A › Dbl homology (DH) domain 0.59 50.0 4.14e-01 97.1% 58.5%
1ihgA02 1.25.40.10 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › Tetratricopeptide repeat domain 0.58 48.0 4.25e-01 88.2% 68.3%
2lqgA00 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.58 49.0 4.47e-01 94.1% 72.5%
7dl9B02 1.20.1250.20 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains 0.58 49.0 3.84e-01 89.2% 52.2%
3kyiA00 1.20.120.160 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain 0.58 50.0 4.64e-01 96.1% 99.2%
8sbeA02 1.20.1250.20 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains 0.56 48.0 3.89e-01 91.2% 57.2%
4ri6A02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.56 44.0 4.26e-01 87.3% 73.9%
2fx0A02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.56 44.0 4.12e-01 94.1% 68.2%
1sr2A00 1.20.120.160 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain 0.54 37.0 3.60e-01 91.2% 62.1%
1vdyA00 1.25.40.90 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.54 44.0 3.99e-01 90.2% 80.7%
ECOD (93)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3353480 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.83 52.0 4.83e-01 93.1% 52.0%
3902495 603.1.1.23 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Sec20 0.82 71.0 5.41e-01 92.2% 64.5%
3577937 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.81 70.0 6.76e-01 92.2% 87.8%
3892002 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.81 74.0 6.28e-01 96.1% 93.5%
3397028 603.1.1.23 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Sec20 0.80 68.0 5.35e-01 89.2% 48.2%
3516162 603.1.1.23 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Sec20 0.79 70.0 5.82e-01 94.1% 60.0%
3684136 604.1.1.154 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › PF27021 0.79 68.0 6.64e-01 91.2% 100.0%
3496310 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.78 65.0 6.15e-01 88.2% 85.8%
3704699 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.78 67.0 6.94e-01 92.2% 100.0%
3669330 604.1.1.148 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › TBCC_N 0.78 61.0 6.56e-01 91.2% 100.0%
3318923 603.1.1.124 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › V-SNARE, V-SNARE_C 0.77 69.0 5.90e-01 95.1% 80.6%
1145703 604.5.1.3 alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › ArAE_1_C 0.77 66.0 6.86e-01 91.2% 98.9%
3202583 604.6.1.1 alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain › GAT 0.76 63.0 6.39e-01 93.1% 90.0%
3184584 603.1.1.100 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › PF27017 0.76 68.0 6.17e-01 97.1% 83.0%
3312910 603.1.1.111 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › TBCC_N 0.75 62.0 6.52e-01 95.1% 98.9%
3506533 3684.1.1.0 alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like 0.75 68.0 5.61e-01 98.0% 79.4%
3990051 604.5.1.2 alpha bundles › Spectrin repeat-like › PhoU-like (Pfam 01895) › PhoU-like (Pfam 01895) › PhoU 0.75 65.0 5.12e-01 94.1% 50.0%
3473984 603.1.1.97 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Syntaxin, SNARE 0.75 69.0 5.06e-01 100.0% 55.3%
3614441 150.1.1.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin 0.75 68.0 5.82e-01 99.0% 66.9%
3490044 603.1.1.99 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › PF27021 0.74 64.0 5.91e-01 94.1% 80.8%
3936807 603.1.1.1 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › Syntaxin 0.74 62.0 5.01e-01 90.2% 87.9%
3969575 601.3.1.1 alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain › Hpt 0.74 53.0 4.79e-01 89.2% 56.3%
3972329 633.5.1.0 alpha bundles › Bromodomain-like › LemA-like › LemA-like 0.73 54.0 4.55e-01 76.5% 93.3%
3517342 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.73 63.0 5.18e-01 94.1% 60.5%
3740645 604.6.1.1 alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain › GAT 0.73 59.0 6.20e-01 91.2% 98.9%
3692512 604.6.1.0 alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain 0.72 64.0 5.94e-01 100.0% 76.2%
3405261 604.22.1.1 alpha bundles › Spectrin repeat-like › tubulin binding cofactor C N-terminal domain › tubulin binding cofactor C N-terminal domain › TBCC_N 0.72 62.0 5.85e-01 98.0% 78.3%
3504303 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.72 61.0 6.20e-01 91.2% 100.0%
3603360 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.72 63.0 6.10e-01 97.1% 92.2%
3970386 601.4.1.0 alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains 0.72 64.0 5.78e-01 96.1% 74.1%
3641813 604.6.1.1 alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain › GAT 0.71 59.0 6.13e-01 95.1% 96.8%
3478117 603.1.1.17 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › SNARE 0.71 62.0 5.06e-01 96.1% 75.8%
3631429 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.71 63.0 5.37e-01 96.1% 72.5%
3912101 604.6.1.1 alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain › GAT 0.71 60.0 6.12e-01 94.1% 94.0%
3481122 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.71 60.0 6.06e-01 92.2% 100.0%
3487223 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.70 60.0 6.22e-01 94.1% 100.0%
3734058 604.6.1.1 alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain › GAT 0.70 63.0 6.29e-01 98.0% 96.2%
3784493 603.1.1.17 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › SNARE 0.70 61.0 4.60e-01 96.1% 45.2%
3572847 604.1.1.162 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › DUF4716 0.70 60.0 5.80e-01 93.1% 86.1%
3222454 2002.1.1.150 a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › NAGidase 0.70 61.0 3.91e-01 95.1% 90.8%
3211477 603.2.1.14 alpha bundles › STAT-like › STAT › STAT › STATB_N 0.70 59.0 5.27e-01 92.2% 83.4%
3616727 603.1.1.98 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › SNARE, Syntaxin_2 0.70 61.0 4.84e-01 97.1% 72.9%
3186004 604.6.1.1 alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain › GAT 0.70 59.0 5.97e-01 92.2% 94.0%
3587934 1075.1.2.0 alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › MacB transmembrane domain 0.70 58.0 4.49e-01 91.2% 86.8%
5081021 5067.1.1.0 alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain 0.70 54.0 4.83e-01 83.3% 62.8%
3994734 109.3.1.297 alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › CUE 0.69 61.0 4.44e-01 97.1% 72.1%
3221766 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.69 60.0 6.00e-01 95.1% 95.2%
3770274 603.1.1.198 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › DUF4716 0.69 57.0 5.91e-01 89.2% 100.0%
3691077 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.69 61.0 5.48e-01 98.0% 87.1%
3586442 604.6.1.1 alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain › GAT 0.68 59.0 5.80e-01 97.1% 90.0%
3346653 604.6.1.1 alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain › GAT 0.67 59.0 5.89e-01 100.0% 95.2%
4124285 601.1.1.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.67 55.0 4.90e-01 97.1% 62.8%
3805103 604.6.1.1 alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain › GAT 0.67 56.0 5.59e-01 98.0% 89.5%
3236489 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.66 57.0 5.18e-01 94.1% 72.6%
3781725 3291.1.1.12 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › DUF1689 0.66 46.0 4.33e-01 71.6% 80.8%
3253936 601.1.1.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin 0.66 56.0 5.13e-01 93.1% 71.9%
3524427 604.1.1.113 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › SYNE3 0.66 57.0 5.70e-01 95.1% 92.4%
3724188 109.3.1.93 alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › DUF6987 0.66 55.0 4.35e-01 92.2% 54.9%
3231871 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.66 55.0 5.07e-01 91.2% 73.1%
3205696 310.2.1.0 a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF 0.66 56.0 5.17e-01 96.1% 94.1%
3269103 604.6.1.0 alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain 0.65 55.0 4.94e-01 93.1% 69.0%
3163928 1075.5.1.4 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › Polysacc_synt 0.65 53.0 4.30e-01 88.2% 71.8%
3576407 622.4.1.0 alpha bundles › YvfG-like › Mite allergen Der p 5-related › Mite allergen Der p 5-related 0.65 54.0 5.27e-01 92.2% 100.0%
3419853 192.29.1.19 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › Cornichon 0.65 57.0 5.06e-01 96.1% 69.7%
3740238 601.1.2.0 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) 0.65 56.0 4.87e-01 97.1% 64.8%
3823532 192.29.1.19 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › Cornichon 0.65 56.0 5.04e-01 96.1% 69.7%
3655350 5069.1.1.10 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › DUF4079 0.64 58.0 5.04e-01 100.0% 72.9%
4020089 6155.1.1.2 alpha duplicates or obligate multimers › TOG superfamily › SWEET transporter › SWEET transporter › PQ-loop 0.64 52.0 4.70e-01 94.1% 63.6%
5057941 1075.5.1.0 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter 0.64 51.0 4.34e-01 86.3% 61.2%
3713984 3615.1.1.0 alpha bundles › Bacterial dynamin-like protein helical domain › Bacterial dynamin-like protein helical domain › Bacterial dynamin-like protein helical domain 0.64 58.0 5.17e-01 98.0% 98.6%
3807101 3684.1.1.20 alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › DUF4079 0.64 57.0 5.13e-01 100.0% 77.9%
3919099 621.1.1.8 alpha bundles › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain › GVIN1 0.64 54.0 4.92e-01 92.2% 86.7%
3940580 604.6.1.14 alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain › RasGAP_C 0.64 58.0 5.59e-01 100.0% 93.9%
3890798 161.1.1.7 alpha complex topology › Helical scaffold and wing domains of SecA › Helical scaffold and wing domains of SecA › Helical scaffold and wing domains of SecA › Serinc 0.64 50.0 4.29e-01 83.3% 91.9%
3572533 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.64 55.0 4.09e-01 97.1% 37.5%
4564490 2500.1.1.2 a/b barrels › Ten stranded beta/alpha barrel › Ten stranded beta/alpha barrel › Ten stranded beta/alpha barrel › Ribonuc_red_lgC 0.64 50.0 3.14e-01 92.2% 15.4%
4020884 603.5.1.6 alpha bundles › STAT-like › FlgN-like › FlgN-like › DUF6987 0.63 55.0 4.77e-01 98.0% 77.6%
3928548 601.4.1.48 alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains › Cornichon 0.63 56.0 5.01e-01 99.0% 76.6%
4942036 1075.5.1.8 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › Polysacc_synt_3 0.63 45.0 3.51e-01 73.5% 65.7%
4137366 109.3.1.181 alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat › Serinc 0.63 50.0 4.28e-01 84.3% 92.5%
4488200 604.12.1.0 alpha bundles › Spectrin repeat-like › MIT domain › MIT domain 0.63 56.0 5.52e-01 100.0% 100.0%
3989110 1075.5.1.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MatE 0.62 52.0 4.19e-01 92.2% 80.5%
3251839 601.1.2.4 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › Talin_R4 0.62 54.0 4.96e-01 97.1% 75.6%
5040870 1075.5.1.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter › MatE 0.61 50.0 3.97e-01 91.2% 78.7%
4960309 5058.1.1.101 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › DUF1622 0.61 50.0 4.88e-01 87.3% 86.4%
3931307 601.1.2.4 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) › Talin_R4 0.59 46.0 4.19e-01 85.3% 66.2%
3277788 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.59 53.0 4.03e-01 99.0% 58.8%
4973614 5069.1.3.26 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Fumarate reductase respiratory complex transmembrane subunits › DUF1622 0.57 47.0 4.58e-01 89.2% 89.1%
3769842 7558.1.1.1 a/b three-layered sandwiches › Glycerol-3-phosphate (1)-acyltransferase › Glycerol-3-phosphate (1)-acyltransferase › Glycerol-3-phosphate (1)-acyltransferase › Acyltransferase 0.56 50.0 3.73e-01 98.0% 55.5%
3002372 129.1.1.5 alpha arrays › 6-phosphogluconate dehydrogenase C-terminal domain-like › 6-phosphogluconate dehydrogenase C-terminal domain-like › 6-phosphogluconate dehydrogenase C-terminal domain-like › Ferric_reduct 0.56 47.0 3.68e-01 96.1% 80.7%
3989408 1075.1.1.0 alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › ABCG5/ABCG8 transmembrane domain 0.56 47.0 3.58e-01 95.1% 78.1%
3505857 601.19.1.0 alpha bundles › Four-helical up-and-down bundle › Apolipoprotein › Apolipoprotein 0.55 50.0 4.41e-01 98.0% 76.6%
3943266 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.54 45.0 3.70e-01 89.2% 53.0%
D3 medium residues 149-290
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF20176.4 best DUF6541 31.2 1.00e-07 100.0% 20.9%
CATH (9)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4xvxA03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.61 42.0 4.24e-01 70.4% 94.6%
1y1uA01 1.20.1050.20 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › STAT transcription factor, all-alpha domain 0.59 42.0 3.75e-01 71.8% 97.4%
3p4tA03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.58 41.0 4.06e-01 71.8% 96.7%
1urvA00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.56 43.0 4.27e-01 82.4% 86.4%
7powA01 1.20.120.1760 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › CDP-alcohol phosphotransferase transmembrane (TM) domain 0.55 41.0 3.67e-01 77.5% 72.2%
2fji101 1.10.357.50 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › 0.54 44.0 3.87e-01 87.3% 91.4%
1auwA02 1.20.200.10 Mainly Alpha › Up-down Bundle › Fumarase C; Chain A, domain 2 › Fumarase/aspartase (Central domain) 0.52 43.0 3.65e-01 88.0% 88.2%
4gmnA00 1.25.10.10 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant 0.51 46.0 3.09e-01 100.0% 32.1%
2nrlA00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.50 39.0 3.88e-01 81.7% 92.4%
ECOD (26)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
5039691 109.3.1.0 alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat 0.86 75.0 6.45e-01 92.3% 61.9%
5004522 3352.1.1.0 alpha bundles › STT3/PglB/AglB transmembrane domain › STT3/PglB/AglB transmembrane domain › STT3/PglB/AglB transmembrane domain 0.84 78.0 5.31e-01 100.0% 30.3%
4983607 3352.1.1.0 alpha bundles › STT3/PglB/AglB transmembrane domain › STT3/PglB/AglB transmembrane domain › STT3/PglB/AglB transmembrane domain 0.83 77.0 5.34e-01 100.0% 32.9%
4960586 3352.1.1.0 alpha bundles › STT3/PglB/AglB transmembrane domain › STT3/PglB/AglB transmembrane domain › STT3/PglB/AglB transmembrane domain 0.82 77.0 5.37e-01 100.0% 35.7%
5037300 3352.1.1.0 alpha bundles › STT3/PglB/AglB transmembrane domain › STT3/PglB/AglB transmembrane domain › STT3/PglB/AglB transmembrane domain 0.80 72.0 5.20e-01 100.0% 36.8%
4941642 3352.1.1.0 alpha bundles › STT3/PglB/AglB transmembrane domain › STT3/PglB/AglB transmembrane domain › STT3/PglB/AglB transmembrane domain 0.79 73.0 5.22e-01 100.0% 36.1%
4996744 3352.1.1.8 alpha bundles › STT3/PglB/AglB transmembrane domain › STT3/PglB/AglB transmembrane domain › STT3/PglB/AglB transmembrane domain › PTPS_related 0.79 74.0 5.20e-01 100.0% 35.4%
4996762 3352.1.1.3 alpha bundles › STT3/PglB/AglB transmembrane domain › STT3/PglB/AglB transmembrane domain › STT3/PglB/AglB transmembrane domain › PMT 0.79 73.0 5.45e-01 100.0% 42.1%
4996764 3352.1.1.2 alpha bundles › STT3/PglB/AglB transmembrane domain › STT3/PglB/AglB transmembrane domain › STT3/PglB/AglB transmembrane domain › PMT_2 0.78 72.0 5.25e-01 100.0% 39.4%
5060319 3352.1.1.2 alpha bundles › STT3/PglB/AglB transmembrane domain › STT3/PglB/AglB transmembrane domain › STT3/PglB/AglB transmembrane domain › PMT_2 0.78 73.0 5.28e-01 100.0% 40.5%
5057313 3352.1.1.2 alpha bundles › STT3/PglB/AglB transmembrane domain › STT3/PglB/AglB transmembrane domain › STT3/PglB/AglB transmembrane domain › PMT_2 0.78 73.0 5.20e-01 100.0% 40.3%
4970070 3352.1.1.2 alpha bundles › STT3/PglB/AglB transmembrane domain › STT3/PglB/AglB transmembrane domain › STT3/PglB/AglB transmembrane domain › PMT_2 0.77 72.0 5.13e-01 99.3% 38.1%
3590458 3352.1.1.8 alpha bundles › STT3/PglB/AglB transmembrane domain › STT3/PglB/AglB transmembrane domain › STT3/PglB/AglB transmembrane domain › PTPS_related 0.75 69.0 4.91e-01 99.3% 35.1%
4934584 3352.1.1.0 alpha bundles › STT3/PglB/AglB transmembrane domain › STT3/PglB/AglB transmembrane domain › STT3/PglB/AglB transmembrane domain 0.73 64.0 5.08e-01 100.0% 48.4%
5056770 3352.1.1.2 alpha bundles › STT3/PglB/AglB transmembrane domain › STT3/PglB/AglB transmembrane domain › STT3/PglB/AglB transmembrane domain › PMT_2 0.73 66.0 4.72e-01 97.2% 61.5%
3282747 3352.1.1.15 alpha bundles › STT3/PglB/AglB transmembrane domain › STT3/PglB/AglB transmembrane domain › STT3/PglB/AglB transmembrane domain › GT87 0.70 57.0 4.34e-01 100.0% 38.4%
4016104 109.4.1.356 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Fungal_trans 0.63 50.0 3.44e-01 83.8% 34.7%
4029380 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.61 55.0 4.65e-01 98.6% 59.2%
3697260 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.60 42.0 3.65e-01 71.1% 98.5%
3724992 603.1.1.17 alpha bundles › STAT-like › t-snare proteins › t-snare proteins › SNARE 0.59 42.0 3.34e-01 71.1% 77.0%
4987048 109.10.1.0 alpha superhelices › Repetitive alpha hairpins › Translin › Translin 0.59 52.0 4.87e-01 96.5% 83.4%
3193381 5001.1.1.0 alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like 0.55 47.0 3.86e-01 91.5% 74.1%
4160680 109.4.1.502 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Med12-LCEWAV 0.54 49.0 3.26e-01 100.0% 31.0%
3412831 7015.1.1.0 alpha bundles › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain › Palmitoyltransferase DHHC transmembrane domain 0.53 38.0 3.74e-01 72.5% 92.7%
3244400 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.53 48.0 3.57e-01 100.0% 85.2%
3790404 109.4.1.0 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat 0.50 41.0 3.77e-01 98.6% 65.1%
D4 medium residues 332-459
PDB
Domain cluster: representative
CATH (36)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2pmrA00 1.20.1270.90 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › AF1782-like 0.75 45.0 5.58e-01 81.2% 100.0%
1lrzA03 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.70 35.0 4.98e-01 89.8% 100.0%
2yqyA00 1.20.120.450 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › dinb family like domain 0.68 48.0 4.92e-01 97.7% 74.6%
1sumB01 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.68 36.0 3.96e-01 96.1% 62.6%
4e6nA02 6.10.140.1010 Special › Helix non-globular › Helix Hairpins › 0.66 33.0 4.30e-01 93.8% 89.4%
3qweA00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.66 46.0 3.63e-01 71.1% 83.8%
1wp7A00 1.10.287.770 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › YojJ-like 0.65 34.0 4.42e-01 93.8% 96.9%
4hr1A00 1.20.1270.410 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.65 48.0 4.99e-01 76.6% 95.8%
3o6xA02 1.20.120.1560 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.65 52.0 4.95e-01 85.2% 91.9%
3t6gB00 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.65 45.0 4.51e-01 72.7% 68.7%
3hl0A02 1.20.1090.10 Mainly Alpha › Up-down Bundle › Dehydroquinate synthase-like, alpha domain › Dehydroquinate synthase-like - alpha domain 0.62 44.0 3.91e-01 85.2% 49.2%
1yo7A00 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.58 48.0 5.00e-01 96.1% 99.2%
1rj1A00 1.20.140.40 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Invertase/pectin methylesterase inhibitor family protein 0.57 48.0 4.61e-01 98.4% 81.8%
3craA02 1.10.287.1080 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › MazG-like 0.57 36.0 3.64e-01 79.7% 63.3%
1sj8A02 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.57 48.0 4.89e-01 100.0% 99.2%
5cqgA03 1.10.10.2210 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › 0.56 25.0 3.12e-01 82.0% 65.8%
1eq1A00 1.20.120.20 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein 0.56 47.0 4.39e-01 93.8% 72.3%
1pduA00 1.10.565.10 Mainly Alpha › Orthogonal Bundle › Retinoid X Receptor › Retinoid X Receptor 0.56 48.0 3.98e-01 93.8% 99.1%
3edvB01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.55 35.0 3.48e-01 95.3% 60.3%
4jgiA01 1.10.1240.10 Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › Methionine synthase domain 0.55 32.0 3.87e-01 81.2% 90.0%
1bgcA00 1.20.1250.10 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › 0.55 45.0 4.22e-01 96.1% 72.8%
1jmwA00 1.20.120.30 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Aspartate receptor, ligand-binding domain 0.54 39.0 3.79e-01 75.8% 65.8%
2yfaA02 1.20.1440.210 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 0.54 44.0 4.57e-01 93.0% 94.0%
1wkbA03 1.10.730.10 Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 0.54 37.0 3.84e-01 75.0% 74.4%
4uvmA00 1.20.1250.20 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains 0.54 48.0 3.25e-01 100.0% 39.2%
2cfqA02 1.20.1250.20 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains 0.53 48.0 4.09e-01 100.0% 92.5%
1t72A02 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.53 35.0 3.96e-01 73.4% 87.8%
2q5zB00 1.10.287.1080 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › MazG-like 0.53 32.0 3.62e-01 93.8% 79.8%
3kflA03 1.10.730.10 Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 0.53 43.0 3.92e-01 87.5% 94.9%
7dl9B02 1.20.1250.20 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains 0.52 46.0 4.03e-01 100.0% 99.0%
3o7pA01 1.20.1250.20 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains 0.52 45.0 3.85e-01 96.9% 91.7%
8h4pA01 1.10.600.10 Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase 0.51 41.0 3.23e-01 89.1% 95.4%
4u7iA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.51 35.0 3.95e-01 76.6% 95.7%
4gc0A02 1.20.1250.20 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains 0.51 45.0 3.80e-01 100.0% 80.5%
2oduA02 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.51 37.0 4.02e-01 75.8% 91.4%
1ileA03 1.10.730.10 Mainly Alpha › Orthogonal Bundle › Isoleucyl-tRNA Synthetase; Domain 1 › Isoleucyl-tRNA Synthetase; Domain 1 0.51 42.0 3.66e-01 88.3% 63.4%
ECOD (76)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
5012657 632.11.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like 0.71 48.0 5.49e-01 74.2% 93.7%
3647788 632.1.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › Families 57/38 glycoside transferase middle domain › Families 57/38 glycoside transferase middle domain 0.68 48.0 5.46e-01 74.2% 98.9%
3692483 3755.4.1.0 alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain 0.64 47.0 4.26e-01 75.0% 78.2%
4140649 140.1.1.4 alpha bundles › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › tRNA-synt_1e,DALR_2 0.61 43.0 4.24e-01 73.4% 82.1%
3745002 601.1.1.98 alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › PF27524 0.60 44.0 4.16e-01 75.8% 98.1%
3186527 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.58 52.0 4.30e-01 100.0% 82.9%
3724837 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.57 52.0 4.22e-01 100.0% 80.8%
4010333 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.57 52.0 4.33e-01 100.0% 90.9%
3982121 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.57 44.0 4.01e-01 82.0% 63.4%
3945617 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.57 49.0 4.40e-01 96.1% 94.6%
3721208 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.56 51.0 4.30e-01 100.0% 93.9%
3813600 633.4.1.1 alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI 0.56 47.0 4.70e-01 96.1% 94.1%
5049263 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.56 50.0 4.30e-01 100.0% 91.9%
3957445 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.56 41.0 4.36e-01 78.9% 85.2%
3742401 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.55 50.0 4.23e-01 100.0% 89.8%
3172011 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.55 50.0 4.19e-01 100.0% 89.5%
3976756 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.55 49.0 4.21e-01 100.0% 89.0%
3697052 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.55 49.0 4.17e-01 100.0% 90.7%
5076868 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.55 48.0 4.24e-01 100.0% 93.0%
3429331 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.55 49.0 4.20e-01 100.0% 91.0%
4826576 150.1.1.5 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin › DUF305 0.55 36.0 4.11e-01 70.3% 98.8%
3750858 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.54 48.0 3.95e-01 100.0% 80.0%
4978685 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.54 43.0 3.80e-01 85.2% 64.2%
3491562 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.54 47.0 4.02e-01 100.0% 85.3%
2642997 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.54 46.0 4.14e-01 99.2% 95.4%
3440427 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.54 47.0 3.99e-01 100.0% 91.1%
3869297 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.54 47.0 3.98e-01 100.0% 83.6%
3279693 5050.1.1.60 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_3 0.53 47.0 4.09e-01 100.0% 90.0%
3287410 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.53 47.0 4.12e-01 100.0% 91.6%
3178339 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.53 46.0 3.96e-01 100.0% 83.6%
4971768 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.53 46.0 4.11e-01 97.7% 94.7%
4410536 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.53 45.0 4.03e-01 96.9% 92.3%
3627931 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.53 42.0 3.51e-01 84.4% 60.0%
3599020 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.53 46.0 3.99e-01 100.0% 87.4%
3738413 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.53 46.0 3.97e-01 100.0% 85.9%
3280349 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.53 47.0 4.11e-01 100.0% 94.4%
3693145 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.53 46.0 4.00e-01 100.0% 87.3%
3190090 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.53 47.0 3.84e-01 100.0% 77.1%
3280348 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.53 46.0 4.05e-01 100.0% 93.0%
3870187 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.52 45.0 3.89e-01 100.0% 87.6%
5079610 5050.1.1.1 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr 0.52 46.0 4.00e-01 100.0% 90.2%
3608820 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.52 46.0 3.96e-01 100.0% 87.4%
4979759 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.52 45.0 3.99e-01 99.2% 98.0%
3971653 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.52 46.0 4.08e-01 100.0% 98.9%
3690688 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.52 45.0 4.03e-01 100.0% 95.9%
3731713 5050.1.1.1 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr 0.52 41.0 3.30e-01 84.4% 48.1%
3801210 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.52 45.0 3.73e-01 100.0% 77.9%
3179436 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.52 44.0 3.87e-01 100.0% 87.4%
3932082 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.52 46.0 3.93e-01 100.0% 92.6%
4955946 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.52 46.0 4.19e-01 100.0% 96.6%
4962298 5059.1.1.1 alpha bundles › Drug/Metabolite transporter › Drug/Metabolite transporter › Drug/Metabolite transporter › EamA 0.52 43.0 3.38e-01 92.2% 90.8%
4443875 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.52 45.0 3.80e-01 100.0% 81.3%
3941776 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.52 45.0 3.93e-01 100.0% 94.1%
3587615 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.51 46.0 4.08e-01 100.0% 100.0%
3945104 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.51 44.0 3.80e-01 100.0% 86.2%
3721821 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.51 45.0 3.53e-01 100.0% 62.4%
4544919 140.1.1.4 alpha bundles › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › tRNA-synt_1e,DALR_2 0.51 43.0 3.69e-01 93.8% 100.0%
4978610 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.51 44.0 3.97e-01 100.0% 94.7%
3388186 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.51 44.0 3.91e-01 100.0% 91.2%
5010974 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.51 44.0 3.90e-01 100.0% 90.2%
3974312 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.51 44.0 3.95e-01 99.2% 98.5%
3476205 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.51 44.0 3.88e-01 96.9% 96.5%
4033448 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.51 44.0 3.86e-01 100.0% 87.6%
3926890 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.51 44.0 3.77e-01 100.0% 83.1%
2774319 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.51 44.0 3.73e-01 98.4% 86.5%
3584465 5050.1.1.0 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter 0.51 41.0 4.13e-01 86.7% 89.2%
3780193 5050.1.1.1 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr 0.51 45.0 4.02e-01 100.0% 95.8%
3685182 5050.1.1.1 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr 0.51 44.0 3.61e-01 100.0% 75.8%
4941333 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.51 44.0 4.03e-01 96.9% 98.9%
3687595 5050.1.1.1 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Sugar_tr 0.51 44.0 3.64e-01 100.0% 79.6%
4033447 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.51 45.0 4.00e-01 100.0% 98.4%
4306496 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.51 44.0 3.70e-01 100.0% 77.4%
4846601 603.5.1.1 alpha bundles › STAT-like › FlgN-like › FlgN-like › FlgN 0.51 36.0 3.76e-01 78.1% 78.7%
3685520 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.50 43.0 3.75e-01 100.0% 84.5%
3532431 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.50 44.0 3.81e-01 100.0% 87.1%
3511776 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.50 44.0 3.83e-01 100.0% 92.7%