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IMGVR_UViG_2905020656_000002-2905020656-2905023018

Arc-Vir

IMGVR_UViG_2905020656_000002-2905020656-2905023018

Identity

Kingdom:
archaea

Quality

83.1 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 6-140
PDB
CATH (84)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4w8hA00 3.40.50.10140 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Toll/interleukin-1 receptor homology (TIR) domain 0.79 69.0 7.12e-01 99.3% 97.6%
2y92A00 3.40.50.10140 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Toll/interleukin-1 receptor homology (TIR) domain 0.77 64.0 6.58e-01 100.0% 92.1%
7o62B01 3.40.50.450 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.77 71.0 7.25e-01 98.5% 100.0%
3qk7A01 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.75 63.0 6.34e-01 100.0% 88.4%
2khzA00 3.40.50.450 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.75 69.0 6.49e-01 100.0% 87.1%
3c5hA00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.74 68.0 5.65e-01 100.0% 95.7%
3f6cA00 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.74 60.0 6.12e-01 100.0% 88.4%
1sulB00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.73 68.0 5.94e-01 100.0% 87.7%
6m8oA00 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.73 59.0 6.33e-01 100.0% 98.3%
7pvaB01 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.73 60.0 6.37e-01 100.0% 98.3%
2j48A00 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.73 59.0 6.26e-01 100.0% 97.5%
5tqjA00 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.72 60.0 6.22e-01 100.0% 95.2%
2i2xB02 3.40.50.280 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Cobalamin-binding domain 0.71 59.0 5.96e-01 100.0% 86.9%
2b4aA00 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.71 56.0 6.01e-01 100.0% 97.4%
1srrC00 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.71 59.0 6.16e-01 99.3% 97.5%
3crnA00 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.71 60.0 6.15e-01 100.0% 93.8%
2yweA01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.71 66.0 6.21e-01 100.0% 93.8%
1p2fA01 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.71 57.0 6.03e-01 98.5% 96.6%
3b2nA00 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.71 59.0 6.21e-01 100.0% 98.3%
6qrjA03 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.71 55.0 6.01e-01 98.5% 100.0%
3h5iA00 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.71 60.0 6.21e-01 100.0% 97.6%
3hzhA00 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.70 59.0 5.94e-01 100.0% 88.8%
3rqiA01 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.70 56.0 5.77e-01 98.5% 89.0%
3eqzB00 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.70 59.0 6.13e-01 100.0% 97.6%
2dy1A01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.70 64.0 5.02e-01 100.0% 97.1%
1a04A01 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.69 58.0 6.09e-01 100.0% 97.6%
5c40B00 3.40.1190.20 Alpha Beta › 3-Layer(aba) Sandwich › UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase › Ribokinase 0.69 64.0 4.83e-01 100.0% 86.2%
4mcjG00 3.40.50.450 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.69 63.0 6.00e-01 97.0% 84.4%
5ul3A01 3.40.50.280 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Cobalamin-binding domain 0.69 64.0 6.12e-01 100.0% 87.2%
4dadA01 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.69 59.0 6.02e-01 100.0% 96.9%
4gvpA01 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.69 57.0 4.91e-01 100.0% 57.8%
1mkyA02 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.68 60.0 5.79e-01 94.8% 98.0%
5dn8A02 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.68 62.0 5.81e-01 100.0% 99.4%
5iz4A00 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.67 62.0 5.03e-01 100.0% 91.9%
3ry7A00 3.40.1190.20 Alpha Beta › 3-Layer(aba) Sandwich › UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase › Ribokinase 0.67 61.0 4.68e-01 100.0% 87.1%
2jjmA01 3.40.50.2000 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glycogen Phosphorylase B; 0.67 61.0 5.51e-01 99.3% 98.9%
3ausA00 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.67 61.0 4.88e-01 100.0% 87.4%
2w7tA00 3.40.50.880 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Class I glutamine amidotransferase (GATase) domain 0.67 61.0 4.86e-01 100.0% 94.3%
3dnfB01 3.40.1010.20 Alpha Beta › 3-Layer(aba) Sandwich › Cobalt-precorrin-4 Transmethylase; domain 1 › 4-hydroxy-3-methylbut-2-enyl diphosphate reductase, catalytic domain 0.66 37.0 4.19e-01 75.6% 73.0%
2cb0A02 3.40.50.10490 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glucose-6-phosphate isomerase like protein; domain 1 0.65 54.0 5.27e-01 99.3% 79.6%
3oidC00 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.65 59.0 4.81e-01 98.5% 91.5%
4wy5A00 3.40.50.1820 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Alpha/Beta hydrolase fold, catalytic domain 0.65 59.0 4.50e-01 100.0% 75.9%
4n7bA01 3.40.1010.20 Alpha Beta › 3-Layer(aba) Sandwich › Cobalt-precorrin-4 Transmethylase; domain 1 › 4-hydroxy-3-methylbut-2-enyl diphosphate reductase, catalytic domain 0.65 41.0 4.39e-01 83.0% 72.4%
4s1wB02 3.40.50.10490 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glucose-6-phosphate isomerase like protein; domain 1 0.65 55.0 5.36e-01 99.3% 83.6%
3nl6C02 3.40.1190.20 Alpha Beta › 3-Layer(aba) Sandwich › UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase › Ribokinase 0.65 60.0 4.61e-01 100.0% 67.3%
3abzA02 3.40.50.1700 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glycoside hydrolase family 3 C-terminal domain 0.65 57.0 5.19e-01 94.8% 81.9%
4e3zB00 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.65 59.0 4.93e-01 99.3% 93.9%
4joqA01 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.65 54.0 5.42e-01 98.5% 87.2%
6cv6D00 3.40.50.9100 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Dehydroquinase, class II 0.65 58.0 5.76e-01 99.3% 98.6%
2zj3A02 3.40.50.10490 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glucose-6-phosphate isomerase like protein; domain 1 0.63 54.0 5.27e-01 97.8% 84.5%
3pffA05 3.40.50.261 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Succinyl-CoA synthetase domains 0.63 58.0 5.31e-01 100.0% 77.7%
2c31A01 3.40.50.970 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Thiamin diphosphate (ThDP)-binding fold, Pyr/PP domains 0.63 51.0 4.63e-01 87.4% 97.9%
3tbfA02 3.40.50.10490 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Glucose-6-phosphate isomerase like protein; domain 1 0.63 54.0 5.24e-01 97.8% 84.6%
3dmyA02 3.40.50.261 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Succinyl-CoA synthetase domains 0.63 54.0 5.43e-01 100.0% 90.7%
5ol0B01 3.40.50.1220 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › TPP-binding domain 0.63 54.0 5.04e-01 94.1% 76.7%
4exbB00 3.20.20.100 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › NADP-dependent oxidoreductase domain 0.63 46.0 3.72e-01 75.6% 85.1%
3qtgA01 3.20.20.60 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Phosphoenolpyruvate-binding domains 0.62 44.0 3.68e-01 73.3% 87.5%
2r8wA00 3.20.20.70 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I 0.62 45.0 3.46e-01 74.8% 74.1%
3afmB00 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.61 54.0 4.53e-01 98.5% 91.9%
2zadA02 3.20.20.120 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Enolase-like C-terminal domain 0.60 43.0 3.63e-01 73.3% 81.7%
2w42B01 3.40.50.2300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Response regulator 0.60 48.0 4.63e-01 98.5% 74.1%
1j0aA02 3.40.50.1100 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.60 41.0 4.57e-01 70.4% 93.3%
1ynsA01 3.40.50.1000 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HAD superfamily/HAD-like 0.59 52.0 5.07e-01 96.3% 94.7%
4p63D00 3.40.910.10 Alpha Beta › 3-Layer(aba) Sandwich › Deoxyhypusine Synthase › Deoxyhypusine synthase 0.58 51.0 3.93e-01 96.3% 82.1%
2bkwA02 3.40.640.10 Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) 0.58 53.0 4.26e-01 100.0% 53.6%
3islA02 3.40.640.10 Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) 0.58 53.0 4.31e-01 100.0% 54.9%
3slkA02 3.90.180.10 Alpha Beta › Alpha-Beta Complex › Quinone Oxidoreductase; Chain A, domain 1 › Medium-chain alcohol dehydrogenases, catalytic domain 0.57 48.0 3.66e-01 91.1% 40.4%
4d8tA02 3.40.50.1100 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.57 42.0 4.58e-01 95.6% 93.6%
6pd1C02 3.40.640.10 Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) 0.57 52.0 4.27e-01 100.0% 54.7%
2dr1A02 3.40.640.10 Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) 0.57 51.0 4.23e-01 100.0% 55.3%
3elbA02 3.40.50.620 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HUPs 0.57 45.0 4.24e-01 84.4% 75.8%
1nijA01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.57 51.0 4.53e-01 100.0% 98.0%
1m32A02 3.40.640.10 Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) 0.56 51.0 4.22e-01 100.0% 55.3%
7e7gA01 3.40.640.10 Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) 0.56 51.0 4.16e-01 100.0% 53.8%
3caiA02 3.40.640.10 Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) 0.56 51.0 4.09e-01 98.5% 52.1%
2g80A01 3.40.50.1000 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › HAD superfamily/HAD-like 0.56 49.0 4.77e-01 94.1% 97.3%
3ffrA02 3.40.640.10 Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) 0.56 50.0 4.10e-01 100.0% 53.4%
3f0hA02 3.40.640.10 Alpha Beta › 3-Layer(aba) Sandwich › Aspartate Aminotransferase; domain 2 › Type I PLP-dependent aspartate aminotransferase-like (Major domain) 0.56 50.0 4.03e-01 100.0% 50.4%
3f2bA02 3.20.20.140 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Metal-dependent hydrolases 0.54 46.0 3.81e-01 93.3% 98.4%
1hkuA02 3.40.50.720 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › NAD(P)-binding Rossmann-like Domain 0.54 44.0 3.91e-01 88.1% 73.7%
4eqsA02 3.50.50.60 Alpha Beta › 3-Layer(bba) Sandwich › FAD/NAD(P)-binding domain › FAD/NAD(P)-binding domain 0.52 45.0 4.43e-01 94.1% 90.9%
3ctlA00 3.20.20.70 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I 0.52 44.0 3.79e-01 94.1% 75.8%
3fkkA00 3.20.20.70 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I 0.50 45.0 3.51e-01 99.3% 71.4%
2lleA00 3.20.20.70 Alpha Beta › Alpha-Beta Barrel › TIM Barrel › Aldolase class I 0.50 45.0 3.80e-01 100.0% 96.2%
ECOD (92)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
5031882 2007.15.1.0 a/b three-layered sandwiches › Flavodoxin-like › N-deoxyribosyltransferase › N-deoxyribosyltransferase 0.92 83.0 8.22e-01 98.5% 90.0%
5032175 2007.15.1.0 a/b three-layered sandwiches › Flavodoxin-like › N-deoxyribosyltransferase › N-deoxyribosyltransferase 0.86 79.0 7.59e-01 100.0% 86.0%
4951140 2007.9.1.3 a/b three-layered sandwiches › Flavodoxin-like › Toll/Interleukin receptor TIR domain › Toll/Interleukin receptor TIR domain › CAP12-PCTIR_TIR 0.86 73.0 7.48e-01 100.0% 92.3%
5021894 2007.9.1.4 a/b three-layered sandwiches › Flavodoxin-like › Toll/Interleukin receptor TIR domain › Toll/Interleukin receptor TIR domain › TIR_2 0.85 74.0 7.68e-01 97.0% 97.6%
4996608 2007.9.1.4 a/b three-layered sandwiches › Flavodoxin-like › Toll/Interleukin receptor TIR domain › Toll/Interleukin receptor TIR domain › TIR_2 0.85 76.0 6.51e-01 100.0% 63.0%
4966509 2007.9.1.4 a/b three-layered sandwiches › Flavodoxin-like › Toll/Interleukin receptor TIR domain › Toll/Interleukin receptor TIR domain › TIR_2 0.84 76.0 7.66e-01 100.0% 95.6%
4106786 2007.15.1.8 a/b three-layered sandwiches › Flavodoxin-like › N-deoxyribosyltransferase › N-deoxyribosyltransferase › CAP12-PCTIR_TIR 0.82 77.0 7.45e-01 100.0% 97.3%
5043885 2007.15.1.2 a/b three-layered sandwiches › Flavodoxin-like › N-deoxyribosyltransferase › N-deoxyribosyltransferase › Nuc_deoxyrib_tr 0.81 76.0 7.66e-01 100.0% 98.5%
4937483 2007.15.1.0 a/b three-layered sandwiches › Flavodoxin-like › N-deoxyribosyltransferase › N-deoxyribosyltransferase 0.81 65.0 7.07e-01 92.6% 99.1%
5041192 2007.9.1.4 a/b three-layered sandwiches › Flavodoxin-like › Toll/Interleukin receptor TIR domain › Toll/Interleukin receptor TIR domain › TIR_2 0.81 72.0 7.09e-01 100.0% 88.3%
5045562 2007.15.1.2 a/b three-layered sandwiches › Flavodoxin-like › N-deoxyribosyltransferase › N-deoxyribosyltransferase › Nuc_deoxyrib_tr 0.80 74.0 7.42e-01 99.3% 97.0%
3261825 2007.15.1.0 a/b three-layered sandwiches › Flavodoxin-like › N-deoxyribosyltransferase › N-deoxyribosyltransferase 0.80 63.0 6.59e-01 100.0% 88.8%
4320688 2007.15.1.2 a/b three-layered sandwiches › Flavodoxin-like › N-deoxyribosyltransferase › N-deoxyribosyltransferase › Nuc_deoxyrib_tr 0.80 76.0 7.53e-01 100.0% 98.6%
5018378 2007.15.1.0 a/b three-layered sandwiches › Flavodoxin-like › N-deoxyribosyltransferase › N-deoxyribosyltransferase 0.80 65.0 6.99e-01 84.4% 100.0%
4958602 2007.15.1.2 a/b three-layered sandwiches › Flavodoxin-like › N-deoxyribosyltransferase › N-deoxyribosyltransferase › Nuc_deoxyrib_tr 0.80 73.0 7.29e-01 98.5% 93.6%
5059581 2007.15.1.0 a/b three-layered sandwiches › Flavodoxin-like › N-deoxyribosyltransferase › N-deoxyribosyltransferase 0.80 72.0 6.99e-01 100.0% 86.7%
4960351 2007.9.1.4 a/b three-layered sandwiches › Flavodoxin-like › Toll/Interleukin receptor TIR domain › Toll/Interleukin receptor TIR domain › TIR_2 0.80 72.0 6.98e-01 96.3% 91.3%
4971285 2007.15.1.2 a/b three-layered sandwiches › Flavodoxin-like › N-deoxyribosyltransferase › N-deoxyribosyltransferase › Nuc_deoxyrib_tr 0.79 74.0 7.36e-01 98.5% 97.9%
4985685 2007.15.1.2 a/b three-layered sandwiches › Flavodoxin-like › N-deoxyribosyltransferase › N-deoxyribosyltransferase › Nuc_deoxyrib_tr 0.79 75.0 7.42e-01 100.0% 96.4%
4352707 2007.15.1.2 a/b three-layered sandwiches › Flavodoxin-like › N-deoxyribosyltransferase › N-deoxyribosyltransferase › Nuc_deoxyrib_tr 0.79 75.0 7.41e-01 99.3% 98.6%
4975427 2007.15.1.2 a/b three-layered sandwiches › Flavodoxin-like › N-deoxyribosyltransferase › N-deoxyribosyltransferase › Nuc_deoxyrib_tr 0.78 70.0 7.18e-01 100.0% 98.5%
3102782 2007.15.1.2 a/b three-layered sandwiches › Flavodoxin-like › N-deoxyribosyltransferase › N-deoxyribosyltransferase › Nuc_deoxyrib_tr 0.76 71.0 6.97e-01 98.5% 97.9%
3629099 2007.9.1.0 a/b three-layered sandwiches › Flavodoxin-like › Toll/Interleukin receptor TIR domain › Toll/Interleukin receptor TIR domain 0.75 68.0 6.61e-01 97.0% 96.7%
5018379 2007.15.1.0 a/b three-layered sandwiches › Flavodoxin-like › N-deoxyribosyltransferase › N-deoxyribosyltransferase 0.75 66.0 6.65e-01 100.0% 93.3%
136673 2007.15.1.2 a/b three-layered sandwiches › Flavodoxin-like › N-deoxyribosyltransferase › N-deoxyribosyltransferase › Nuc_deoxyrib_tr 0.75 69.0 6.49e-01 100.0% 87.1%
3968493 2007.1.3.1 a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg 0.74 59.0 6.17e-01 100.0% 90.4%
167880 2007.1.3.1 a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg 0.74 60.0 6.34e-01 100.0% 95.9%
4951370 2007.1.3.1 a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg 0.73 59.0 6.27e-01 99.3% 95.8%
4939118 2007.1.3.1 a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg 0.73 60.0 6.30e-01 100.0% 96.7%
4346718 2007.1.3.1 a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg 0.73 60.0 6.37e-01 100.0% 99.2%
1893734 2007.1.3.1 a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg 0.72 60.0 6.22e-01 100.0% 95.2%
4964814 2007.1.3.72 a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › HalX 0.72 58.0 5.31e-01 100.0% 66.3%
10043 2007.1.3.1 a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg 0.71 56.0 6.01e-01 100.0% 97.4%
2568308 2007.1.3.1 a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg 0.71 56.0 5.88e-01 100.0% 91.0%
3884937 2004.1.1.122 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › IIGP 0.71 66.0 5.38e-01 100.0% 75.8%
5042694 2007.1.14.0 a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Chelatase-like 0.71 54.0 5.73e-01 100.0% 89.2%
4964836 2007.1.3.1 a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg 0.71 58.0 5.34e-01 100.0% 68.8%
3637902 2004.1.1.19 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Ras 0.71 64.0 5.45e-01 100.0% 96.8%
5074463 2007.1.3.4 a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › B12-binding 0.71 63.0 5.65e-01 100.0% 70.3%
4136811 2004.1.1.73 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › MMR_HSR1 0.70 65.0 5.51e-01 100.0% 79.1%
3401021 2007.9.1.0 a/b three-layered sandwiches › Flavodoxin-like › Toll/Interleukin receptor TIR domain › Toll/Interleukin receptor TIR domain 0.70 65.0 6.21e-01 100.0% 92.9%
3956465 2007.1.2.0 a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Periplasmic binding protein-like I 0.70 59.0 5.82e-01 100.0% 85.7%
3980653 2007.1.3.1 a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg 0.70 59.0 5.76e-01 99.3% 83.4%
3403478 2007.15.1.4 a/b three-layered sandwiches › Flavodoxin-like › N-deoxyribosyltransferase › N-deoxyribosyltransferase › Nuc_deoxyri_tr2 0.69 64.0 6.30e-01 100.0% 100.0%
3184621 2007.1.3.1 a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg 0.69 59.0 5.92e-01 100.0% 90.4%
3589573 2007.1.4.2 a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Phosphofructokinase N-terminal domain › DAGK_cat 0.69 56.0 5.96e-01 97.8% 98.3%
147673 2007.1.3.0 a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like 0.69 59.0 6.04e-01 100.0% 97.6%
4261023 2003.1.1.69 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › adh_short_C2 0.68 63.0 4.95e-01 100.0% 87.2%
4954782 2007.1.14.0 a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Chelatase-like 0.68 50.0 5.49e-01 98.5% 93.6%
4013455 2003.1.1.0 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains 0.68 62.0 4.96e-01 100.0% 89.4%
3875609 2004.1.1.512 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › URGCP 0.68 62.0 4.63e-01 100.0% 50.3%
3693282 2003.1.1.3 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains › adh_short 0.68 62.0 4.93e-01 100.0% 89.1%
5013107 2007.1.14.0 a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › Chelatase-like 0.67 49.0 5.23e-01 100.0% 87.8%
4989941 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.67 56.0 5.81e-01 99.3% 95.2%
5070945 7522.1.1.4 a/b three-layered sandwiches › TK C-terminal domain-like › TK C-terminal domain-like › TK C-terminal domain-like › PFOR_II 0.67 48.0 5.02e-01 96.3% 82.5%
4939796 2007.13.1.0 a/b three-layered sandwiches › Flavodoxin-like › Rossmann-like domains in magnesium chelatase catalytic subunit › Rossmann-like domains in magnesium chelatase catalytic subunit 0.67 57.0 5.75e-01 100.0% 91.9%
3831336 2007.13.1.2 a/b three-layered sandwiches › Flavodoxin-like › Rossmann-like domains in magnesium chelatase catalytic subunit › Rossmann-like domains in magnesium chelatase catalytic subunit › DUF3479 0.66 61.0 5.69e-01 100.0% 90.9%
5000511 2006.1.4.3 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › NYN 0.66 53.0 4.97e-01 85.2% 84.8%
4207825 2007.1.3.1 a/b three-layered sandwiches › Flavodoxin-like › Class I glutamine amidotransferase-like › CheY-like › Response_reg 0.66 57.0 5.18e-01 100.0% 70.9%
5042030 2007.6.1.4 a/b three-layered sandwiches › Flavodoxin-like › Ribosomal protein S2/SIS domain › Ribosomal protein S2/SIS domain › SIS 0.66 56.0 5.25e-01 97.8% 75.2%
5065275 2006.1.4.3 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › NYN 0.65 52.0 5.25e-01 84.4% 100.0%
5064221 7522.1.1.0 a/b three-layered sandwiches › TK C-terminal domain-like › TK C-terminal domain-like › TK C-terminal domain-like 0.65 50.0 4.68e-01 98.5% 65.5%
5056289 2006.1.4.3 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › NYN 0.65 54.0 4.82e-01 88.9% 97.4%
3697788 2006.1.4.3 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › NYN 0.65 48.0 4.58e-01 76.3% 96.8%
5031003 2006.1.4.3 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › NYN 0.64 53.0 4.98e-01 88.1% 99.4%
4971463 2007.6.1.0 a/b three-layered sandwiches › Flavodoxin-like › Ribosomal protein S2/SIS domain › Ribosomal protein S2/SIS domain 0.64 54.0 4.97e-01 97.8% 69.4%
4980524 2006.1.4.3 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › NYN 0.64 52.0 4.80e-01 88.1% 96.0%
5035356 2006.1.4.3 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › NYN 0.64 52.0 4.63e-01 88.9% 97.0%
3605878 2006.1.4.0 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like 0.64 50.0 4.50e-01 84.4% 99.5%
4074592 2003.1.4.10 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › DHS-like NAD/FAD-binding domain › TPP_enzyme_M_2 0.63 54.0 4.99e-01 94.1% 73.5%
4967734 2006.1.4.3 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › NYN 0.63 53.0 5.42e-01 90.4% 100.0%
4987900 2006.1.2.1 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › DHH phosphoesterases › DHH 0.63 53.0 4.72e-01 94.8% 63.1%
4254011 2007.6.1.4 a/b three-layered sandwiches › Flavodoxin-like › Ribosomal protein S2/SIS domain › Ribosomal protein S2/SIS domain › SIS 0.63 53.0 4.88e-01 97.8% 69.4%
3939442 2006.1.6.0 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › vWA-like 0.63 55.0 5.34e-01 96.3% 99.3%
4947905 2007.6.1.4 a/b three-layered sandwiches › Flavodoxin-like › Ribosomal protein S2/SIS domain › Ribosomal protein S2/SIS domain › SIS 0.63 54.0 4.89e-01 97.8% 68.6%
5014193 2006.1.4.3 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › NYN 0.63 51.0 4.78e-01 87.4% 81.8%
5063937 2002.1.1.39 a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › Glyco_hydro_3 0.62 55.0 3.72e-01 98.5% 25.4%
3452896 2006.1.1.3 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like › Trehalose_PPase 0.62 56.0 4.35e-01 100.0% 87.0%
3213946 2003.1.7.2 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NagB/RpiA/CoA transferase-like › IF-2B 0.62 54.0 4.71e-01 92.6% 82.6%
4497071 2002.1.1.44 a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › TatD_DNase 0.62 48.0 3.93e-01 83.7% 98.1%
5023184 2004.1.1.159 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Mur_ligase_M 0.61 54.0 4.13e-01 97.8% 78.8%
4976916 2006.1.4.3 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › NYN 0.61 45.0 4.72e-01 76.3% 100.0%
4315670 2006.1.4.17 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like › DUF188 0.61 51.0 5.29e-01 96.3% 96.8%
5020609 7512.1.1.30 a/b three-layered sandwiches › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › UDP-Glycosyltransferase/glycogen phosphorylase › Glyco_transf_4 0.59 50.0 4.83e-01 91.9% 94.8%
3829199 2006.1.4.0 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like 0.58 46.0 4.80e-01 83.7% 90.4%
4955570 2002.1.1.0 a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels 0.57 50.0 4.08e-01 94.8% 78.4%
4978139 2002.1.1.134 a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › Amidohydro_2 0.56 51.0 3.93e-01 100.0% 90.5%
5004283 300.1.1.18 a+b three layers › Phospholipase D/nuclease › Phospholipase D/nuclease › Phospholipase D/nuclease › FilR1_middle 0.56 41.0 3.89e-01 75.6% 96.2%
5028201 2002.1.1.77 a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › RNase_P_p30 0.53 40.0 3.72e-01 80.0% 96.1%
3729019 2002.1.1.48 a/b barrels › TIM beta/alpha-barrel › TIM barrels › TIM barrels › FMN_dh 0.52 44.0 3.23e-01 91.9% 83.9%
4130118 2003.2.1.1 a/b three-layered sandwiches › Rossmann-like › Formate dehydrogenase/DMSO reductase, domains 2 and 3 › Formate dehydrogenase/DMSO reductase, domains 2 and 3 › Molybdopterin 0.51 43.0 3.73e-01 91.1% 70.5%
4255201 2484.1.1.7 mixed a+b and a/b › Ribonuclease H-like › Ribonuclease H-like › Ribonuclease H-like › Ribosomal_S11 0.51 36.0 3.94e-01 84.4% 90.9%
D2 high residues 148-188
PDB
Domain cluster: representative
CATH (45)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1j2jB00 1.20.5.170 Mainly Alpha › Up-down Bundle › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.96 82.0 8.26e-01 95.1% 92.7%
3ix7A00 3.40.50.1010 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 5'-nuclease 0.92 77.0 5.28e-01 92.7% 29.0%
2nwlC00 1.10.3860.10 Mainly Alpha › Orthogonal Bundle › Proton glutamate symport protein › Sodium:dicarboxylate symporter 0.89 77.0 4.39e-01 100.0% 10.2%
3c5wA00 1.25.10.10 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant 0.86 67.0 4.11e-01 85.4% 15.8%
3ea5D00 1.25.10.10 Mainly Alpha › Alpha Horseshoe › Leucine-rich Repeat Variant › Leucine-rich Repeat Variant 0.84 71.0 3.83e-01 100.0% 4.9%
3oo3A00 1.10.630.10 Mainly Alpha › Orthogonal Bundle › Cytochrome p450 › Cytochrome P450 0.84 73.0 4.19e-01 100.0% 11.3%
3txsC01 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.83 73.0 5.96e-01 100.0% 58.7%
4fb2A00 1.10.630.10 Mainly Alpha › Orthogonal Bundle › Cytochrome p450 › Cytochrome P450 0.83 69.0 4.00e-01 100.0% 10.7%
1owlA02 1.25.40.80 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.82 69.0 5.00e-01 100.0% 34.1%
2chnB03 1.20.58.460 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Hyaluronidase post-catalytic domain-like 0.82 71.0 4.57e-01 97.6% 41.1%
5mi7A03 1.20.58.460 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Hyaluronidase post-catalytic domain-like 0.82 71.0 4.25e-01 97.6% 28.0%
3sfvB02 6.10.140.2010 Special › Helix non-globular › Helix Hairpins › 0.81 70.0 4.44e-01 100.0% 21.0%
4iggB02 1.20.120.230 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like 0.80 71.0 5.04e-01 100.0% 66.1%
3bjdA01 1.10.1240.20 Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › Lytic transglycosylase, superhelical linker domain 0.80 66.0 5.13e-01 92.7% 45.5%
3m1cB01 3.30.390.170 Alpha Beta › 2-Layer Sandwich › Enolase-like; domain 1 › 0.79 57.0 4.18e-01 78.0% 33.0%
3fseB02 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.78 69.0 4.68e-01 100.0% 29.9%
1xjaB00 2.60.120.280 Mainly Beta › Sandwich › Jelly Rolls › Regulatory protein AraC 0.78 65.0 4.40e-01 97.6% 26.6%
4fvmA06 1.10.287.690 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › B family DNA polymerase, finger domain 0.76 61.0 5.84e-01 90.2% 81.2%
2oh3A01 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.76 66.0 4.50e-01 100.0% 29.9%
2gv9A05 1.10.287.690 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › B family DNA polymerase, finger domain 0.76 64.0 5.78e-01 100.0% 71.2%
3kkbA00 1.20.120.880 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Histidine kinase (KinB), sensor domain 0.75 66.0 4.67e-01 100.0% 79.4%
1fioA00 1.20.58.70 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.75 65.0 4.20e-01 100.0% 22.6%
4l0rB00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.74 62.0 5.25e-01 100.0% 58.9%
3ppuB02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.73 62.0 4.59e-01 100.0% 39.8%
2ee4A01 1.10.555.10 Mainly Alpha › Orthogonal Bundle › Phosphatidylinositol 3-kinase; Chain A › Rho GTPase activation protein 0.72 54.0 3.53e-01 100.0% 18.2%
4o92A02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.72 59.0 4.52e-01 100.0% 40.0%
1z0jB00 4.10.860.20 Few Secondary Structures › Irregular › DNA Excision Repair, Uvrb; Chain A › Rabenosyn, Rab binding domain 0.71 58.0 5.55e-01 97.6% 82.4%
2mbgA01 1.10.555.10 Mainly Alpha › Orthogonal Bundle › Phosphatidylinositol 3-kinase; Chain A › Rho GTPase activation protein 0.71 55.0 3.53e-01 85.4% 30.2%
3h36A00 1.10.10.400 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Polyribonucleotide nucleotidyltransferase, RNA-binding domain 0.71 62.0 5.06e-01 100.0% 52.6%
3l0mA02 1.20.1280.280 Mainly Alpha › Up-down Bundle › Monooxygenase › 0.70 60.0 4.91e-01 100.0% 64.1%
4q5rA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.70 57.0 4.32e-01 100.0% 50.9%
2rkhA02 1.20.1280.20 Mainly Alpha › Up-down Bundle › Monooxygenase › HscB, C-terminal domain 0.70 62.0 5.08e-01 100.0% 56.6%
1r4gA00 1.10.8.10 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › Ubiquitin-associated (UBA) domain 0.69 53.0 4.92e-01 87.8% 66.0%
1vw4L01 3.90.1030.10 Alpha Beta › Alpha-Beta Complex › 50s Ribosomal Protein L17; Chain: A, › Ribosomal protein L17 0.69 57.0 3.95e-01 92.7% 30.4%
4htpB00 1.10.3260.10 Mainly Alpha › Orthogonal Bundle › DNA ligase i, domain 1 › DNA ligase, ATP-dependent, N-terminal domain 0.69 55.0 3.55e-01 100.0% 19.4%
4hkaA02 1.10.287.3810 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.68 56.0 5.16e-01 90.2% 76.5%
7ztbB01 3.30.460.10 Alpha Beta › 2-Layer Sandwich › Beta Polymerase; domain 2 › Beta Polymerase, domain 2 0.67 56.0 3.84e-01 100.0% 25.2%
1ufhA00 3.40.630.30 Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Gcn5-related N-acetyltransferase (GNAT) 0.67 46.0 3.12e-01 75.6% 19.4%
3bcvA00 3.90.550.10 Alpha Beta › Alpha-Beta Complex › Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A › Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A 0.66 52.0 3.40e-01 92.7% 19.4%
1tmxB00 2.60.130.10 Mainly Beta › Sandwich › Protocatechuate 3,4-Dioxygenase, subunit A › Aromatic compound dioxygenase 0.65 56.0 3.40e-01 97.6% 14.3%
3vurA02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.64 53.0 3.96e-01 100.0% 50.4%
2xkoA02 1.10.10.10 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain 0.61 45.0 3.48e-01 78.0% 33.0%
4fd4A00 3.40.630.30 Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Gcn5-related N-acetyltransferase (GNAT) 0.60 54.0 3.38e-01 100.0% 20.3%
3oyxA02 1.20.58.1560 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.59 42.0 3.89e-01 95.1% 55.2%
3tw8A03 6.10.140.1000 Special › Helix non-globular › Helix Hairpins › 0.54 45.0 4.51e-01 92.7% 92.7%
ECOD (42)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4010516 10.12.1.8 beta sandwiches › jelly-roll › Double-stranded beta-helix › Double-stranded beta-helix › AraC_binding 0.94 84.0 5.55e-01 97.6% 28.3%
3187132 386.1.1.10 few secondary structure elements › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › beta-beta-alpha zinc fingers › MAT1 0.89 71.0 6.08e-01 92.7% 55.4%
3706828 109.4.1.3254 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Importin_rep_4, TPR_IPO5 0.88 73.0 3.83e-01 90.2% 47.0%
3988736 632.17.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › C protein alpha-antigen helical bundle domain › C protein alpha-antigen helical bundle domain 0.84 69.0 6.11e-01 92.7% 63.3%
3683800 109.4.1.2662 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › HEAT, Importin_rep_4, Importin_rep_6, HEAT_GCN1, TPR_IMB1, TPR_IPO5 0.83 68.0 3.58e-01 90.2% 3.3%
3976663 3812.1.1.1 alpha bundles › Type III secretion protein YscE › Type III secretion protein YscE › Type III secretion protein YscE › T3SS_needle_E 0.83 75.0 6.38e-01 100.0% 66.2%
3977737 3831.1.1.1 alpha bundles › Secreted protein of unknown function DUF1311 › Secreted protein of unknown function DUF1311 › Secreted protein of unknown function DUF1311 › LprI 0.82 66.0 4.77e-01 95.1% 32.2%
4423918 5045.1.1.1 alpha bundles › F1F0 ATP synthase subunit A › F1F0 ATP synthase subunit A › F1F0 ATP synthase subunit A › ATP-synt_A 0.81 71.0 4.31e-01 100.0% 17.2%
3361840 3796.1.1.0 alpha arrays › Iron-regulated surface determinant protein H linker domain › Iron-regulated surface determinant protein H linker domain › Iron-regulated surface determinant protein H linker domain 0.80 65.0 6.65e-01 90.2% 95.0%
3447429 109.4.1.1471 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › TPR_IPO5 0.79 67.0 4.14e-01 95.1% 36.8%
3492075 3729.1.1.1 alpha arrays › Legumain prodomain › Legumain prodomain › Legumain prodomain › Legum_prodom 0.79 70.0 4.92e-01 100.0% 33.9%
3855328 4006.1.1.1 alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF 0.79 68.0 5.21e-01 100.0% 44.2%
3489618 109.4.1.871 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › INTS1_R4 0.78 59.0 3.82e-01 85.4% 18.6%
57654 4970.1.1.0 alpha bundles › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I › fingers domain in bacteriophage RB69-like DNA polymerase I 0.78 67.0 6.17e-01 100.0% 79.6%
3987389 2004.1.1.5 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › ABC_tran 0.78 67.0 3.75e-01 100.0% 8.5%
3619577 192.5.1.0 alpha bundles › Long alpha-hairpin › HR1 repeat › HR1 repeat 0.78 68.0 5.26e-01 100.0% 47.8%
3757869 4006.1.1.0 alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain 0.77 67.0 5.14e-01 100.0% 44.2%
4136151 4006.1.1.1 alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF 0.77 64.0 4.83e-01 100.0% 39.0%
3484694 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.77 67.0 3.91e-01 100.0% 13.0%
5071514 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.77 65.0 5.32e-01 95.1% 85.3%
3811835 7076.1.1.0 0.77 66.0 5.70e-01 100.0% 66.2%
4001318 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.76 67.0 5.51e-01 100.0% 57.3%
4041347 192.7.1.2 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N 0.76 67.0 4.88e-01 100.0% 39.1%
5077460 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.75 61.0 5.28e-01 95.1% 70.6%
3279737 564.1.1.4 alpha arrays › N-terminal, cytoplasmic domain of anti-sigma factors › N-terminal, cytoplasmic domain of anti-sigma factors › N-terminal, cytoplasmic domain of anti-sigma factors › RskA_N 0.75 64.0 5.60e-01 95.1% 91.7%
2095477 1170.1.2.2 beta barrels › IL8-related › IL8-related › chemokine-related domain in glycoprotein L (gL) 0.75 59.0 4.11e-01 90.2% 28.8%
4040184 605.1.1.4 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA_3 0.75 65.0 6.14e-01 100.0% 86.0%
3402327 3755.3.1.324 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › DUF725 0.74 64.0 4.25e-01 100.0% 65.9%
3414399 5086.1.1.106 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › DUF725 0.74 62.0 4.12e-01 100.0% 24.1%
3614078 3922.1.1.0 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 0.74 63.0 4.56e-01 100.0% 35.8%
4975245 603.1.1.0 alpha bundles › STAT-like › t-snare proteins › t-snare proteins 0.72 58.0 4.76e-01 100.0% 50.0%
3385229 2003.1.9.1 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › Activating enzymes of the ubiquitin-like proteins › ThiF 0.72 60.0 3.53e-01 100.0% 11.8%
3602838 101.1.8.0 alpha arrays › HTH › HTH › DNA breaking-rejoining enzymes 0.71 56.0 3.89e-01 87.8% 26.4%
4147979 4006.1.1.1 alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF 0.71 60.0 4.62e-01 100.0% 42.0%
4429835 4006.1.1.1 alpha bundles › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › Release factor (Pfam 00472) N-terminal alpha helical domain › PCRF 0.70 59.0 4.52e-01 100.0% 45.0%
3409567 3755.3.1.324 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin › DUF725 0.69 60.0 3.96e-01 100.0% 26.7%
4297392 192.6.1.1 alpha bundles › Long alpha-hairpin › Epsilon subunit of F1F0-ATP synthase C-terminal domain › Epsilon subunit of F1F0-ATP synthase C-terminal domain › ATP-synt_DE 0.68 55.0 5.27e-01 100.0% 78.0%
3580283 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.65 50.0 4.28e-01 100.0% 48.2%
None 0.64 47.0 3.05e-01 78.0% 15.2%
3232664 192.17.1.0 alpha bundles › Long alpha-hairpin › Rabenosyn-5 Rab-binding domain-like › Rabenosyn-5 Rab-binding domain-like 0.64 44.0 4.31e-01 73.2% 68.9%
5081198 4244.1.1.0 a/b three-layered sandwiches › EreA/ChaN-like › EreA/ChaN-like › EreA/ChaN-like 0.61 46.0 3.15e-01 90.2% 21.7%
3998578 142.1.1.41 alpha complex topology › Sigma2 domain-like › Sigma2 domain of RNA polymerase sigma factors › Sigma2 domain of RNA polymerase sigma factors › RabGAP-TBC 0.51 42.0 3.66e-01 100.0% 60.0%
D3 high residues 198-276
PDB
Domain cluster: representative
CATH (75)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4abmD00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.89 72.0 7.34e-01 88.6% 87.0%
1cxzB00 1.10.287.160 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat 0.88 67.0 6.53e-01 84.8% 73.3%
2lm9A00 1.20.58.970 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.88 68.0 6.32e-01 86.1% 66.7%
3mq1A01 1.20.58.970 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.88 69.0 6.52e-01 87.3% 70.7%
3na7A00 1.10.287.1490 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.86 67.0 4.63e-01 88.6% 27.4%
3l9fA02 6.10.140.1570 Special › Helix non-globular › Helix Hairpins › 0.85 65.0 6.49e-01 82.3% 77.8%
1vw4T01 6.10.330.20 Special › Helix non-globular › Monooxygenase › 0.85 66.0 5.77e-01 84.8% 57.1%
4wpeA00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.84 69.0 4.62e-01 87.3% 26.5%
3hr0B01 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.84 68.0 6.89e-01 87.3% 87.3%
4mh6A00 1.10.287.1700 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.84 68.0 5.27e-01 87.3% 42.8%
4nb5B02 1.10.287.160 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat 0.83 64.0 7.00e-01 84.8% 100.0%
1uurA01 1.20.58.240 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › STAT; domain 1 0.83 63.0 5.58e-01 86.1% 57.3%
1sumB01 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.83 65.0 5.79e-01 87.3% 60.7%
1t72A02 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.83 65.0 6.06e-01 83.5% 72.4%
4iloA00 1.10.287.1490 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.83 66.0 4.55e-01 88.6% 28.0%
1yxrA01 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.83 56.0 5.79e-01 74.7% 74.3%
2yevC00 6.10.280.110 Special › Helix non-globular › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.82 62.0 6.87e-01 78.5% 100.0%
4ijjB00 1.20.120.910 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › DksA, coiled-coil domain 0.82 67.0 5.56e-01 86.1% 56.2%
3rq9A00 1.10.287.2500 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.82 59.0 5.94e-01 83.5% 75.6%
4aflA00 6.10.140.1740 Special › Helix non-globular › Helix Hairpins › 0.81 67.0 6.08e-01 88.6% 67.6%
3lssA01 1.10.287.40 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain 0.81 70.0 6.11e-01 91.1% 89.3%
4hr1A00 1.20.1270.410 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › 0.81 61.0 5.25e-01 81.0% 52.5%
2y39A00 1.20.120.1490 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.81 71.0 6.33e-01 94.9% 76.4%
1urfA00 1.10.287.160 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat 0.81 67.0 6.72e-01 89.9% 90.1%
2ix5A03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.81 71.0 5.59e-01 94.9% 52.9%
1x4tA01 1.10.287.660 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.80 57.0 6.51e-01 78.5% 100.0%
3d36B02 1.10.287.130 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Signal transduction histidine kinase, dimerisation/phosphotransfer (DHp) domain 0.80 56.0 6.22e-01 77.2% 93.4%
1j5wA02 1.20.58.180 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Class II aaRS and biotin synthetases; domain 2 0.80 55.0 5.56e-01 73.4% 72.7%
1vctA01 1.20.58.220 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphate transport system protein phou homolog 2; domain 2 0.80 62.0 5.51e-01 82.3% 63.3%
1u5pA01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.79 63.0 5.65e-01 84.8% 65.7%
4biuE01 1.10.287.130 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Signal transduction histidine kinase, dimerisation/phosphotransfer (DHp) domain 0.79 58.0 5.39e-01 87.3% 62.2%
2dw4A03 1.10.287.80 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ATP synthase, gamma subunit, helix hairpin domain 0.79 65.0 5.98e-01 88.6% 72.3%
2gscC00 1.20.1440.60 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 23S rRNA-intervening sequence 0.78 60.0 5.32e-01 94.9% 58.2%
4v1gA00 1.20.20.10 Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C 0.78 65.0 6.40e-01 89.9% 84.7%
2ficB00 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.78 69.0 5.13e-01 98.7% 79.6%
1cunA01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.78 56.0 5.14e-01 75.9% 62.7%
3icxA01 1.10.287.660 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.78 62.0 6.35e-01 87.3% 90.7%
1lvfB00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.77 63.0 5.67e-01 86.1% 66.3%
4dylA01 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.77 65.0 4.49e-01 91.1% 71.6%
2js5A00 1.10.287.660 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.77 59.0 6.19e-01 81.0% 90.1%
5dn6J00 1.20.20.10 Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C 0.77 62.0 6.39e-01 86.1% 91.9%
1yg2A02 6.10.140.190 Special › Helix non-globular › Helix Hairpins › 0.76 61.0 5.81e-01 84.8% 78.9%
3r84A00 1.10.287.3490 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.76 62.0 6.17e-01 87.3% 98.8%
1ydxA02 1.10.287.1120 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Bipartite methylase S protein 0.76 61.0 5.91e-01 87.3% 80.0%
2dq0A01 1.10.287.40 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain 0.76 63.0 5.75e-01 92.4% 97.2%
2gl2B00 1.10.287.1700 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.76 60.0 5.41e-01 86.1% 63.3%
5jrcA00 1.20.58.2140 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.76 55.0 4.14e-01 78.5% 32.3%
4nsmA00 6.10.250.2770 Special › Helix non-globular › Single alpha-helices involved in coiled-coils or other helix-helix interfaces › 0.75 59.0 6.26e-01 86.1% 93.0%
1gaxA05 1.10.287.380 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Valyl-tRNA synthetase, C-terminal domain 0.75 57.0 5.91e-01 81.0% 87.7%
1ij5A01 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.74 59.0 6.07e-01 91.1% 90.8%
1wp7A00 1.10.287.770 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › YojJ-like 0.74 56.0 6.08e-01 82.3% 100.0%
2q0oC00 1.10.287.160 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat 0.74 59.0 5.80e-01 87.3% 80.2%
2efkA01 1.20.1270.60 Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain 0.74 65.0 4.53e-01 98.7% 77.5%
3pe0A01 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.74 54.0 4.97e-01 77.2% 60.4%
3qo8A01 1.10.287.40 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain 0.74 63.0 5.69e-01 93.7% 88.7%
7ymiZ01 1.10.287.740 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Photosystem II PsbZ, reaction centre 0.73 51.0 5.74e-01 81.0% 98.3%
4okvE00 6.10.140.1890 Special › Helix non-globular › Helix Hairpins › 0.73 56.0 6.06e-01 91.1% 98.5%
4rm7A03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.73 62.0 5.15e-01 94.9% 57.6%
1u7lA02 1.20.1460.10 Mainly Alpha › Up-down Bundle › subunit c (vma5p) of the yeast v-atpase, domain 2 › subunit c (vma5p) of the yeast v-atpase, domain 2 0.72 62.0 4.77e-01 96.2% 82.0%
2b5uA02 1.10.287.620 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix Hairpins 0.72 55.0 4.45e-01 84.8% 87.0%
4it4A02 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.72 55.0 5.27e-01 82.3% 70.3%
3t98B00 6.10.140.1350 Special › Helix non-globular › Helix Hairpins › 0.71 57.0 5.62e-01 87.3% 81.4%
2lw1A00 1.10.287.380 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Valyl-tRNA synthetase, C-terminal domain 0.71 56.0 5.53e-01 87.3% 81.2%
1vf7A03 1.10.287.470 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.70 51.0 5.70e-01 77.2% 100.0%
6qumQ00 1.20.20.10 Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C 0.70 54.0 5.59e-01 89.9% 90.5%
3jcuZ00 1.10.287.740 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Photosystem II PsbZ, reaction centre 0.70 51.0 5.53e-01 78.5% 100.0%
6tqfA01 1.20.1560.10 Mainly Alpha › Up-down Bundle › ABC transporter transmembrane region fold › ABC transporter type 1, transmembrane domain 0.70 62.0 3.97e-01 100.0% 37.1%
4oydB00 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.69 59.0 5.18e-01 93.7% 63.2%
4u7iA00 1.20.58.80 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit 0.69 50.0 4.79e-01 87.3% 65.6%
4l8jA04 1.10.287.470 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.69 49.0 5.43e-01 74.7% 100.0%
1wleA01 1.10.287.40 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Serine-tRNA synthetase, tRNA binding domain 0.67 59.0 5.25e-01 98.7% 99.1%
3rrkA02 1.20.1460.20 Mainly Alpha › Up-down Bundle › subunit c (vma5p) of the yeast v-atpase, domain 2 › 0.67 57.0 4.61e-01 94.9% 71.0%
3uumA00 1.20.58.60 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.67 52.0 4.61e-01 87.3% 56.6%
6xxvC00 1.10.132.20 Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor 0.65 55.0 4.92e-01 92.4% 65.8%
1zbtA01 6.10.140.1950 Special › Helix non-globular › Helix Hairpins › 0.61 56.0 5.53e-01 100.0% 95.2%
ECOD (82)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3968144 605.1.1.1 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA 0.93 71.0 7.82e-01 82.3% 96.9%
4649114 3559.1.1.1 a+b complex topology › Mediator of RNA polymerase II transcription subunit 22 › Mediator of RNA polymerase II transcription subunit 22 › Mediator of RNA polymerase II transcription subunit 22 › Med22 0.90 68.0 6.17e-01 87.3% 62.0%
4946455 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.89 75.0 7.54e-01 88.6% 87.5%
3890044 3922.1.1.0 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 0.89 71.0 7.59e-01 83.5% 97.1%
4096596 223.1.1.0 a+b three layers › Profilin-like › sensor domains › sensor domains 0.86 69.0 4.14e-01 83.5% 14.8%
4523639 5086.1.1.92 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_AprE 0.86 71.0 5.22e-01 87.3% 37.9%
3973695 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.86 71.0 5.19e-01 87.3% 45.3%
4036645 5086.1.1.92 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_AprE 0.86 71.0 5.16e-01 87.3% 44.1%
141918 101.1.2.49 alpha arrays › HTH › HTH › winged helix domain › PadR,Vir_act_alpha_C 0.85 65.0 4.94e-01 82.3% 37.1%
3973283 325.1.7.27 a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif › HH_AprE 0.84 69.0 5.06e-01 87.3% 36.9%
3975632 5086.1.1.92 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_AprE 0.84 69.0 5.13e-01 87.3% 38.9%
5012108 2004.1.1.0 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases 0.84 73.0 4.77e-01 92.4% 25.2%
3505608 192.29.1.1 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB_dom 0.84 66.0 6.76e-01 82.3% 86.7%
1313624 5086.1.1.92 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_AprE 0.83 69.0 5.31e-01 88.6% 60.5%
3266175 3755.4.1.0 alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain 0.83 68.0 5.95e-01 87.3% 60.0%
5060491 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.83 68.0 5.89e-01 88.6% 59.2%
2429105 4992.1.1.0 extended segments › RelB-like › RelB-like › RelB-like 0.83 64.0 6.65e-01 82.3% 100.0%
3735607 192.29.1.0 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) 0.82 66.0 6.64e-01 87.3% 86.3%
3973285 3755.1.1.28 alpha bundles › YscO-like › Putative type III secretion protein YscO-related › Putative type III secretion protein YscO-related › PF25876 0.82 67.0 5.52e-01 87.3% 94.8%
3968781 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.82 68.0 5.45e-01 88.6% 69.7%
3550353 3602.1.1.0 alpha bundles › Kinase suppressor of Ras 1 helical hairpin domain › Kinase suppressor of Ras 1 helical hairpin domain › Kinase suppressor of Ras 1 helical hairpin domain 0.82 61.0 6.66e-01 87.3% 95.4%
4006721 325.1.7.50 a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif › PF25876 0.82 66.0 6.51e-01 87.3% 84.7%
4563674 192.7.1.4 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Val_tRNA-synt_C 0.81 64.0 6.81e-01 83.5% 94.3%
3192159 4207.1.2.0 alpha duplicates or obligate multimers › Mediator hinge subcomplex-like › Mediator hinge subcomplex-like › MED7 hinge region 0.81 74.0 6.55e-01 98.7% 91.8%
4642325 5086.1.1.84 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_MFP_RND 0.81 67.0 5.61e-01 88.6% 88.5%
3971758 5086.1.1.84 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_MFP_RND 0.81 66.0 6.47e-01 87.3% 84.7%
3968997 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.80 66.0 5.55e-01 88.6% 88.5%
5083949 5086.1.1.84 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_MFP_RND 0.80 66.0 5.52e-01 88.6% 99.2%
3740490 4177.1.1.0 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like 0.80 72.0 5.13e-01 100.0% 77.8%
5063047 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.80 68.0 6.32e-01 93.7% 74.0%
4959390 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.79 60.0 6.28e-01 79.7% 95.7%
3947741 5086.1.1.84 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_MFP_RND 0.79 64.0 5.56e-01 87.3% 66.7%
4940099 2004.1.1.198 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › AAA_23 0.79 71.0 4.45e-01 97.5% 21.4%
4420750 192.7.1.4 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Val_tRNA-synt_C 0.79 62.0 6.60e-01 84.8% 94.3%
3720652 4177.1.1.5 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › Vps5 0.79 72.0 4.92e-01 100.0% 70.2%
3969543 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.78 64.0 6.53e-01 87.3% 94.7%
4045132 192.8.1.0 alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain 0.78 64.0 5.68e-01 87.3% 87.3%
4009031 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.78 63.0 6.16e-01 87.3% 100.0%
4174593 3922.1.1.248 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › PF25876 0.78 63.0 6.47e-01 87.3% 96.0%
3702347 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.78 63.0 4.87e-01 88.6% 43.4%
3965957 5086.1.1.84 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_MFP_RND 0.78 63.0 6.43e-01 86.1% 94.7%
3987006 5086.1.1.93 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_EMRA 0.78 63.0 5.19e-01 87.3% 55.7%
3969814 5086.1.1.84 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_MFP_RND 0.78 64.0 6.56e-01 88.6% 96.0%
4267909 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.78 63.0 4.66e-01 87.3% 44.1%
4983461 3922.1.1.0 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 0.77 63.0 5.43e-01 87.3% 59.2%
3964187 5086.1.1.84 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_MFP_RND 0.77 63.0 6.32e-01 87.3% 88.7%
3166260 1.1.7.123 beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C › PF25885 0.77 63.0 5.28e-01 87.3% 60.0%
None 0.77 60.0 3.86e-01 83.5% 18.9%
3694833 3755.3.1.0 alpha bundles › YscO-like › CT398 helical hairpin › CT398 helical hairpin 0.77 63.0 5.32e-01 88.6% 85.4%
3981585 5086.1.1.84 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_MFP_RND 0.77 63.0 6.47e-01 88.6% 96.0%
4606689 148.1.3.26 alpha arrays › Histone-like › Histone-related › AAA+ ATPase lid domain › AAA_lid_9 0.77 65.0 4.75e-01 89.9% 57.9%
1759951 5086.1.1.88 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_CyaD 0.77 62.0 4.64e-01 87.3% 37.5%
4010479 325.1.7.48 a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif › PF25885 0.77 62.0 5.22e-01 87.3% 60.8%
3964081 5069.1.1.0 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes 0.76 68.0 5.44e-01 96.2% 98.0%
3382780 2006.1.1.8 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like › 5_nucleotid 0.76 63.0 4.01e-01 87.3% 19.7%
3971026 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.76 63.0 5.41e-01 89.9% 61.6%
3386973 5086.1.1.84 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_MFP_RND 0.76 62.0 5.95e-01 88.6% 95.6%
3551506 4177.1.1.1 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FCH 0.76 64.0 4.29e-01 92.4% 66.0%
3967813 5086.1.1.93 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_EMRA 0.76 62.0 5.26e-01 88.6% 60.8%
3331502 192.8.1.0 alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain 0.76 61.0 4.16e-01 88.6% 24.6%
3973636 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.76 62.0 6.39e-01 88.6% 96.0%
3974231 5086.1.1.84 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_MFP_RND 0.76 60.0 6.32e-01 84.8% 98.6%
3837413 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.75 60.0 4.84e-01 86.1% 45.3%
3670746 3291.1.1.0 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related 0.75 60.0 5.24e-01 87.3% 58.3%
3974625 5086.1.1.84 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_MFP_RND 0.75 61.0 6.40e-01 87.3% 100.0%
3945031 5086.1.1.86 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_YBHG 0.75 61.0 5.13e-01 87.3% 55.4%
3984493 325.1.7.28 a+b complex topology › alpha/beta-Hammerhead/Barrel-sandwich hybrid › alpha/beta-Hammerhead/Barrel-sandwich hybrid › Single hybrid motif › HH_YBHG 0.75 61.0 5.12e-01 87.3% 57.7%
4362754 5086.1.1.86 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_YBHG 0.75 61.0 5.26e-01 87.3% 58.3%
3169497 4323.1.1.1 alpha bundles › helical bundle domain in vacuolar ATP synthase subunit C › helical bundle domain in vacuolar ATP synthase subunit C › helical bundle domain in vacuolar ATP synthase subunit C › V_ATPase_I 0.75 65.0 5.45e-01 96.2% 69.6%
3708789 3922.1.1.0 alpha bundles › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 › Helical domain in structural maintenance of chromosomes protein 3 0.74 60.0 5.66e-01 88.6% 73.7%
4525341 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.74 60.0 6.31e-01 87.3% 100.0%
3948872 5086.1.1.0 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins 0.74 59.0 5.05e-01 87.3% 55.4%
4429194 192.7.1.2 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N 0.73 59.0 5.37e-01 91.1% 90.9%
1291200 4177.1.1.1 alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FCH 0.73 64.0 4.37e-01 100.0% 73.8%
5077093 4323.1.1.0 alpha bundles › helical bundle domain in vacuolar ATP synthase subunit C › helical bundle domain in vacuolar ATP synthase subunit C › helical bundle domain in vacuolar ATP synthase subunit C 0.72 61.0 5.16e-01 94.9% 80.7%
3970512 5086.1.1.189 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_CzcB 0.72 56.0 5.72e-01 82.3% 86.7%
4258322 5086.1.1.189 alpha bundles › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › helical hairpin of HlyD-like secretion proteins › HH_CzcB 0.72 55.0 5.80e-01 82.3% 92.9%
4263341 192.7.1.2 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N 0.71 62.0 5.53e-01 98.7% 95.7%
4654983 605.2.1.3 alpha duplicates or obligate multimers › ROP-like › Hypothetical protein D-63 › Hypothetical protein D-63 › Seryl_tRNA_N 0.70 59.0 5.36e-01 94.9% 93.6%
4028291 2004.1.1.87 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SMC_N 0.70 56.0 3.55e-01 88.6% 16.9%
3496957 2003.1.2.0 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › FAD/NAD(P)-binding domain 0.68 54.0 3.26e-01 88.6% 12.3%
3494616 4106.1.1.1 few secondary structure elements › Zinc hairpin stack › Zinc hairpin stack › Zinc hairpin stack › DHHC 0.62 49.0 4.79e-01 86.1% 78.8%