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IMGVR_UViG_2905025277_000001-2905025277-2905027278
Arc-VirIMGVR_UViG_2905025277_000001-2905025277-2905027278
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 6-141
Domain cluster:
rep: IMGVR_UViG_2554235478_000002-2554235478-2556103456__D1-134
CATH (33)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3layF00 | 1.20.120.1490 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.69 | 39.0 | 4.98e-01 | 73.5% | 96.2% |
| 4oydB00 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.65 | 43.0 | 4.64e-01 | 72.1% | 77.8% |
| 2m6uA00 | 1.20.81.20 | Mainly Alpha › Up-down Bundle › Receptor-associated Protein › | 0.62 | 35.0 | 4.28e-01 | 89.7% | 90.2% |
| 7xxiA01 | 1.20.1070.10 | Mainly Alpha › Up-down Bundle › Rhopdopsin 7-helix transmembrane proteins › Rhodopsin 7-helix transmembrane proteins | 0.61 | 43.0 | 3.42e-01 | 72.8% | 34.1% |
| 6vudA01 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.61 | 38.0 | 4.23e-01 | 71.3% | 78.0% |
| 1dd5A01 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.61 | 38.0 | 4.20e-01 | 72.8% | 78.0% |
| 1wdzA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.60 | 43.0 | 3.60e-01 | 73.5% | 74.9% |
| 3jrtA00 | 1.20.120.1060 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.60 | 42.0 | 3.94e-01 | 80.1% | 58.4% |
| 1i4dA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.60 | 44.0 | 3.94e-01 | 75.0% | 76.6% |
| 1iurA01 | 1.10.287.110 | Mainly Alpha › Orthogonal Bundle › Helix Hairpins › DnaJ domain | 0.58 | 28.0 | 4.03e-01 | 78.7% | 100.0% |
| 2q12A00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.58 | 42.0 | 3.46e-01 | 74.3% | 65.3% |
| 4ehsA00 | 1.10.860.10 | Mainly Alpha › Orthogonal Bundle › DNAb Helicase; Chain A › DNAb Helicase; Chain A | 0.57 | 42.0 | 4.38e-01 | 91.2% | 82.3% |
| 3behB01 | 1.20.120.540 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Voltage-gated potassium channels | 0.57 | 34.0 | 3.69e-01 | 76.5% | 68.4% |
| 1h6gA01 | 1.20.120.230 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Alpha-catenin/vinculin-like | 0.57 | 38.0 | 4.05e-01 | 93.4% | 77.3% |
| 3g9gA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.57 | 41.0 | 3.36e-01 | 73.5% | 77.2% |
| 8ek4A01 | 1.20.120.20 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Apolipoprotein | 0.57 | 40.0 | 4.05e-01 | 71.3% | 75.2% |
| 2vxgA02 | 1.10.220.100 | Mainly Alpha › Orthogonal Bundle › Annexin V; domain 1 › conserved c-terminal region of ge- 1 | 0.56 | 32.0 | 3.95e-01 | 86.0% | 89.4% |
| 2ex3B02 | 1.20.1270.230 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › DNA terminal protein Gp3, priming domain | 0.56 | 31.0 | 3.81e-01 | 95.6% | 87.7% |
| 3x29A00 | 1.20.140.150 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › | 0.54 | 44.0 | 4.19e-01 | 89.0% | 81.3% |
| 5c8aA01 | 1.10.1240.10 | Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › Methionine synthase domain | 0.54 | 30.0 | 3.75e-01 | 81.6% | 92.3% |
| 2j1oA00 | 1.10.600.10 | Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase | 0.53 | 46.0 | 3.82e-01 | 100.0% | 51.4% |
| 2fcwA00 | 1.20.81.10 | Mainly Alpha › Up-down Bundle › Receptor-associated Protein › RAP domain | 0.53 | 39.0 | 4.32e-01 | 83.1% | 97.2% |
| 2pfdA03 | 1.20.120.680 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Formiminotetrahydrofolate cyclodeaminase monomer, up-and-down helical bundle | 0.53 | 46.0 | 4.07e-01 | 97.1% | 87.7% |
| 4dyqA01 | 1.10.10.60 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like | 0.53 | 37.0 | 4.22e-01 | 98.5% | 96.1% |
| 1st6A03 | 1.20.120.810 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Vinculin, Vh2 four-helix bundle | 0.52 | 43.0 | 3.66e-01 | 89.0% | 89.1% |
| 1uurA01 | 1.20.58.240 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › STAT; domain 1 | 0.52 | 36.0 | 3.92e-01 | 78.7% | 85.5% |
| 4tpjA00 | 1.20.1250.20 | Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains | 0.52 | 40.0 | 2.75e-01 | 78.7% | 84.9% |
| 3ok8A00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.52 | 41.0 | 3.53e-01 | 83.8% | 84.5% |
| 3owaA03 | 1.20.140.10 | Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 | 0.52 | 43.0 | 4.04e-01 | 90.4% | 87.7% |
| 3pltA00 | 1.20.1270.60 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Arfaptin homology (AH) domain/BAR domain | 0.51 | 44.0 | 3.83e-01 | 94.9% | 92.1% |
| 3bt5A00 | 1.20.1260.10 | Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle | 0.51 | 42.0 | 4.13e-01 | 89.0% | 83.4% |
| 2rldA00 | 1.20.1440.60 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 23S rRNA-intervening sequence | 0.51 | 37.0 | 3.99e-01 | 85.3% | 90.4% |
| 1q16C01 | 1.20.950.20 | Mainly Alpha › Up-down Bundle › Fumarate Reductase Cytochrome B subunit › Transmembrane di-heme cytochromes, Chain C | 0.50 | 36.0 | 3.10e-01 | 74.3% | 49.1% |
ECOD (41)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 2878134 | 150.1.1.0 ↗ | alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Ferritin | 0.73 | 42.0 | 4.17e-01 | 74.3% | 54.3% |
| 3699787 | 4177.1.1.0 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like | 0.66 | 47.0 | 3.87e-01 | 73.5% | 88.3% |
| 3267886 | 4177.1.1.8 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › BAR_3 | 0.64 | 44.0 | 3.58e-01 | 70.6% | 81.2% |
| 3260043 | 5001.1.1.123 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › PF29575 | 0.64 | 45.0 | 3.25e-01 | 71.3% | 33.3% |
| 3939680 | 4177.1.1.3 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › Arfaptin | 0.64 | 46.0 | 3.82e-01 | 74.3% | 83.0% |
| 3522695 | 4177.1.1.2 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › BAR | 0.63 | 44.0 | 3.57e-01 | 71.3% | 65.2% |
| 3956688 | 5050.1.1.9 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 | 0.63 | 47.0 | 4.05e-01 | 77.9% | 70.9% |
| 3483587 | 4177.1.1.0 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like | 0.62 | 44.0 | 3.67e-01 | 73.5% | 77.9% |
| 3212070 | 5001.1.1.41 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Srw | 0.62 | 47.0 | 3.48e-01 | 77.9% | 82.8% |
| 3855578 | 5050.1.1.0 ↗ | alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter | 0.62 | 46.0 | 3.77e-01 | 76.5% | 63.3% |
| 3235225 | 4177.1.1.5 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › Vps5 | 0.62 | 44.0 | 3.76e-01 | 72.8% | 90.0% |
| 3254000 | 4177.1.1.8 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › BAR_3 | 0.61 | 44.0 | 3.57e-01 | 74.3% | 80.0% |
| 3396804 | 603.1.1.104 ↗ | alpha bundles › STAT-like › t-snare proteins › t-snare proteins › 7tm_7 | 0.61 | 54.0 | 3.97e-01 | 97.8% | 78.2% |
| 3710154 | 2007.2.3.9 ↗ | a/b three-layered sandwiches › Flavodoxin-like › Flavoproteins/Phosphotyrosine protein phosphatases-like › (Phosphotyrosine protein) phosphatases II › PTPlike_phytase | 0.61 | 47.0 | 4.25e-01 | 91.9% | 58.4% |
| 1036846 | 310.2.1.1 ↗ | a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF › RRF | 0.61 | 40.0 | 4.19e-01 | 72.1% | 73.3% |
| 3213281 | 4177.1.1.1 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › FCH | 0.60 | 44.0 | 3.52e-01 | 76.5% | 85.2% |
| 3584613 | 1075.4.1.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › ABC_membrane | 0.59 | 45.0 | 3.51e-01 | 80.9% | 47.3% |
| 3426522 | 3562.1.1.11 ↗ | alpha bundles › Calcium release-activated calcium channel protein 1 › Calcium release-activated calcium channel protein 1 › Calcium release-activated calcium channel protein 1 › PGG | 0.58 | 50.0 | 5.03e-01 | 91.9% | 91.1% |
| 3501178 | 3755.4.1.31 ↗ | alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Fry_C | 0.58 | 48.0 | 4.22e-01 | 90.4% | 77.6% |
| 4071991 | 310.2.1.1 ↗ | a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF › RRF | 0.58 | 40.0 | 3.67e-01 | 72.1% | 86.5% |
| 2033699 | 601.7.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain | 0.57 | 37.0 | 3.50e-01 | 78.7% | 52.7% |
| 3989648 | 1203.1.2.17 ↗ | alpha bundles › Shroom domain 2 › Shroom domain 2 › Human SD2 › ABC_membrane | 0.57 | 44.0 | 3.86e-01 | 80.9% | 70.5% |
| 3697193 | 604.6.1.0 ↗ | alpha bundles › Spectrin repeat-like › GAT-like domain › GAT-like domain | 0.57 | 45.0 | 4.63e-01 | 94.1% | 87.7% |
| 4034051 | 1075.4.1.1 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › ABC_membrane | 0.57 | 47.0 | 3.58e-01 | 89.7% | 88.3% |
| 3772061 | 109.4.1.809 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Codanin-1_C | 0.56 | 41.0 | 3.10e-01 | 76.5% | 30.3% |
| 3464517 | 3562.1.1.11 ↗ | alpha bundles › Calcium release-activated calcium channel protein 1 › Calcium release-activated calcium channel protein 1 › Calcium release-activated calcium channel protein 1 › PGG | 0.56 | 50.0 | 4.67e-01 | 96.3% | 82.8% |
| 4030659 | 2498.1.1.6 ↗ | mixed a+b and a/b › Zincin-like › "Metalloproteases (""zincins"") catalytic domain" › "Metalloproteases (""zincins"") catalytic domain" › Peptidase_M3 | 0.54 | 43.0 | 2.74e-01 | 83.8% | 44.7% |
| 3231382 | 5001.1.1.27 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Sre | 0.54 | 45.0 | 3.48e-01 | 90.4% | 63.7% |
| 3634169 | 4177.1.1.27 ↗ | alpha duplicates or obligate multimers › BAR/IMD domain-like › BAR/IMD domain-like › BAR/IMD domain-like › BAR_4 | 0.54 | 40.0 | 3.24e-01 | 77.2% | 78.2% |
| 3216699 | 5001.1.1.63 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Srab | 0.54 | 45.0 | 3.51e-01 | 92.6% | 69.5% |
| 4888150 | 1075.4.1.9 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › Type I ABC exporter transmembrane domain fold › ABC_tran+ABC_membrane | 0.54 | 42.0 | 3.26e-01 | 84.6% | 46.5% |
| 4026288 | 1075.5.1.0 ↗ | alpha bundles › Type II ABC exporter transmembrane domain fold › Multidrug and toxic compound extrusion (MATE) transporter › Multidrug and toxic compound extrusion (MATE) transporter | 0.53 | 42.0 | 3.58e-01 | 89.7% | 52.1% |
| 3232821 | 4106.1.1.1 ↗ | few secondary structure elements › Zinc hairpin stack › Zinc hairpin stack › Zinc hairpin stack › DHHC | 0.52 | 43.0 | 3.92e-01 | 91.9% | 94.9% |
| 3782069 | 633.21.1.0 ↗ | alpha bundles › Bromodomain-like › Uncharacterized protein PA2107 › Uncharacterized protein PA2107 | 0.52 | 39.0 | 3.94e-01 | 77.9% | 86.7% |
| 3222173 | 5001.1.1.84 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Srz | 0.51 | 41.0 | 3.34e-01 | 88.2% | 48.9% |
| 4978525 | 4121.1.1.1 ↗ | a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like › CorA | 0.51 | 46.0 | 3.74e-01 | 99.3% | 93.7% |
| 3237172 | 5001.1.1.41 ↗ | alpha bundles › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › Family A G protein-coupled receptor-like › 7TM_GPCR_Srw | 0.51 | 43.0 | 3.30e-01 | 94.1% | 44.9% |
| 3347110 | 3684.1.1.2 ↗ | alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › BPS1 | 0.51 | 38.0 | 3.21e-01 | 79.4% | 58.4% |
| 4021431 | 174.1.1.0 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain | 0.51 | 40.0 | 4.00e-01 | 85.3% | 81.4% |
| 3831865 | 633.4.1.1 ↗ | alpha bundles › Bromodomain-like › Plant invertase/pectin methylesterase inhibitor › Plant invertase/pectin methylesterase inhibitor › PMEI | 0.50 | 38.0 | 3.90e-01 | 78.7% | 86.9% |
| 3596893 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.50 | 45.0 | 2.92e-01 | 98.5% | 41.2% |