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IMGVR_UViG_2914819717_000001-2914819717-2914821919

Arc-Vir

IMGVR_UViG_2914819717_000001-2914819717-2914821919

Identity

Kingdom:
archaea

Quality

86.6 mean pLDDT

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 208-401
PDB
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF25120.2 best DUF7814 40.9 2.60e-10 73.7% 37.7%
CATH (2)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2zttA00 6.10.140.720 Special › Helix non-globular › Helix Hairpins › 0.58 22.0 3.29e-01 89.2% 83.6%
3gziA00 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.52 33.0 3.30e-01 76.3% 59.6%
ECOD (2)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3602827 3962.1.1.7 alpha arrays › N-terminal helical domain in restriction-modification system methylation subunit-like › N-terminal helical domain in restriction-modification system methylation subunit › N-terminal helical domain in restriction-modification system methylation subunit › DUF7814 0.85 75.0 7.60e-01 89.7% 99.5%
4980585 101.1.2.18 alpha arrays › HTH › HTH › winged helix domain › Ribosomal_S19e 0.51 32.0 3.33e-01 88.7% 65.6%
D2 high residues 655-736
PDB
Domain cluster: representative
CATH (64)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1kvkA02 3.30.70.890 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › GHMP kinase, C-terminal domain 0.75 54.0 4.42e-01 75.6% 95.9%
1earA02 3.30.70.790 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › UreE, C-terminal domain 0.70 48.0 5.12e-01 75.6% 84.1%
2mzjA00 3.30.70.330 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain 0.69 49.0 4.95e-01 74.4% 98.8%
3aqoA01 3.30.70.3400 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.67 49.0 4.99e-01 78.0% 98.8%
7e6gA01 3.30.70.270 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Reverse transcriptase/Diguanylate cyclase domain 0.67 49.0 4.08e-01 79.3% 66.4%
1apsA00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.66 49.0 4.67e-01 79.3% 82.7%
3ldgA01 3.30.2130.30 Alpha Beta › 2-Layer Sandwich › VC0802-like › 0.66 47.0 3.63e-01 79.3% 32.0%
3h20A01 3.30.1490.240 Alpha Beta › 2-Layer Sandwich › Dna Ligase; domain 1 › RepB DNA-primase, N-terminal domain 0.66 47.0 5.20e-01 95.1% 92.4%
3pyfA02 3.30.70.890 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › GHMP kinase, C-terminal domain 0.65 47.0 4.03e-01 78.0% 92.7%
3g8qA02 3.30.70.1940 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.65 45.0 4.59e-01 73.2% 92.5%
2wbmA03 3.30.70.240 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.64 48.0 5.08e-01 79.3% 100.0%
1zpwX00 3.30.70.240 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.64 48.0 4.86e-01 79.3% 84.1%
2jvrA00 3.30.70.330 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain 0.64 47.0 4.83e-01 79.3% 97.5%
3cedA00 3.30.70.260 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain 0.64 47.0 4.45e-01 78.0% 81.6%
2dnzA01 3.30.70.330 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain 0.64 47.0 4.52e-01 78.0% 89.2%
2cqpA00 3.30.70.330 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain 0.64 45.0 4.30e-01 74.4% 81.6%
2fyxA00 3.30.70.1290 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Transposase IS200-like 0.64 47.0 4.10e-01 79.3% 78.5%
3im8A02 3.30.70.250 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Malonyl-CoA ACP transacylase, ACP-binding 0.64 47.0 5.00e-01 79.3% 93.2%
1vw4U00 3.30.1390.20 Alpha Beta › 2-Layer Sandwich › Ribosomal Protein L30; Chain: A, › Ribosomal protein L30/L7 0.64 43.0 4.38e-01 78.0% 70.7%
4q6rA02 3.90.1150.10 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 0.64 44.0 3.84e-01 73.2% 67.2%
7vxrA01 3.40.800.10 Alpha Beta › 3-Layer(aba) Sandwich › Arginase; Chain A › Ureohydrolase domain 0.63 47.0 4.46e-01 79.3% 68.4%
1fvqA00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.63 47.0 4.93e-01 79.3% 98.6%
1tr0A00 3.30.70.100 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.63 47.0 4.32e-01 79.3% 95.3%
2i8eA01 3.30.70.240 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.63 46.0 4.82e-01 79.3% 100.0%
1darA05 3.30.70.240 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.62 46.0 4.58e-01 79.3% 81.6%
1lfpA03 3.30.70.980 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › YebC, transcriptional regulation domain 0.62 45.0 4.75e-01 78.0% 87.7%
1h2vZ00 3.30.70.330 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain 0.62 45.0 4.43e-01 79.3% 90.3%
5v7qZ00 3.30.1390.20 Alpha Beta › 2-Layer Sandwich › Ribosomal Protein L30; Chain: A, › Ribosomal protein L30/L7 0.62 42.0 4.73e-01 78.0% 98.3%
6spbZ00 3.30.1390.20 Alpha Beta › 2-Layer Sandwich › Ribosomal Protein L30; Chain: A, › Ribosomal protein L30/L7 0.62 42.0 4.73e-01 78.0% 100.0%
2qswA00 3.30.70.260 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain 0.61 43.0 4.24e-01 74.4% 85.6%
5zwnQ01 3.30.70.330 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain 0.61 41.0 4.21e-01 70.7% 100.0%
4cvqA01 3.90.1150.10 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 0.61 44.0 3.56e-01 75.6% 59.3%
1xszA03 3.30.310.140 Alpha Beta › 2-Layer Sandwich › TATA-Binding Protein › sec7 domains 0.61 43.0 3.52e-01 74.4% 82.8%
2dgwA01 3.30.70.330 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain 0.61 44.0 4.45e-01 75.6% 98.8%
8oh9B05 3.30.70.20 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.61 42.0 4.67e-01 79.3% 100.0%
4erdA00 3.30.70.330 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain 0.61 43.0 3.99e-01 75.6% 74.1%
1nrkA02 3.30.70.1400 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Aminomethyltransferase beta-barrel domains 0.60 44.0 4.41e-01 79.3% 100.0%
2lxiA00 3.30.70.330 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain 0.60 42.0 4.12e-01 74.4% 90.1%
2dgvA01 3.30.70.330 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain 0.60 44.0 4.35e-01 79.3% 92.0%
2cpfA00 3.30.70.330 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain 0.60 44.0 4.27e-01 81.7% 87.8%
3b82A06 3.30.70.240 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.60 45.0 4.01e-01 81.7% 63.6%
3gmgA00 3.30.70.1880 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Protein of unknown function DUF881 0.59 43.0 3.66e-01 78.0% 73.4%
7qddB01 3.30.70.330 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain 0.59 43.0 4.50e-01 78.0% 100.0%
5uazA00 3.30.70.330 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain 0.59 43.0 4.16e-01 78.0% 88.3%
2f9jA01 3.30.70.330 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain 0.59 44.0 4.52e-01 84.1% 100.0%
4qbuA03 3.30.70.250 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Malonyl-CoA ACP transacylase, ACP-binding 0.59 43.0 4.71e-01 79.3% 98.5%
1oo0B00 3.30.70.330 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain 0.59 46.0 4.54e-01 89.0% 95.7%
1nm2A01 3.30.70.250 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Malonyl-CoA ACP transacylase, ACP-binding 0.59 44.0 4.76e-01 84.1% 98.5%
1wi8A01 3.30.70.330 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain 0.59 41.0 4.16e-01 73.2% 100.0%
4id8A00 3.30.70.20 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.59 41.0 4.50e-01 75.6% 100.0%
1gpjA01 3.30.460.30 Alpha Beta › 2-Layer Sandwich › Beta Polymerase; domain 2 › Glutamyl-tRNA reductase, N-terminal domain 0.59 43.0 3.59e-01 78.0% 54.5%
4i0wA00 3.30.70.2980 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.59 50.0 4.90e-01 98.8% 89.1%
4qu6A01 3.30.70.330 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain 0.58 42.0 4.10e-01 78.0% 91.1%
4oi3A00 3.30.70.3090 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ORF SCO4226, nickel-binding ferredoxin-like monomer 0.58 42.0 4.29e-01 79.3% 93.8%
3d3yA02 3.30.830.10 Alpha Beta › 2-Layer Sandwich › Cytochrome Bc1 Complex; Chain A, domain 1 › Metalloenzyme, LuxS/M16 peptidase-like 0.57 51.0 3.87e-01 100.0% 93.7%
8gsxA01 2.60.40.740 Mainly Beta › Sandwich › Immunoglobulin-like › 0.55 48.0 4.00e-01 100.0% 90.7%
1fu0A00 3.30.1340.10 Alpha Beta › 2-Layer Sandwich › Histidine-containing Protein; Chain: A; › HPr-like 0.55 38.0 3.77e-01 73.2% 100.0%
2d3aA02 3.30.590.10 Alpha Beta › 2-Layer Sandwich › Creatine Kinase; Chain A, domain 2 › Glutamine synthetase/guanido kinase, catalytic domain 0.53 44.0 3.27e-01 97.6% 58.7%
2acaA00 2.40.320.10 Mainly Beta › Beta Barrel › Hypothetical Protein Pfu-838710-001 › Hypothetical Protein Pfu-838710-001 0.53 38.0 3.12e-01 78.0% 93.7%
6erkA01 3.90.1150.10 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 0.53 44.0 3.58e-01 92.7% 49.7%
3vkwA01 3.30.450.420 Alpha Beta › 2-Layer Sandwich › Beta-Lactamase › 0.52 34.0 2.88e-01 100.0% 36.7%
1ad2A01 3.30.190.20 Alpha Beta › 2-Layer Sandwich › Ribulose 1,5 Bisphosphate Carboxylase/Oxygenase › Ribosomal protein L1/L10, rRNA-binding domain 0.52 43.0 3.93e-01 100.0% 91.7%
4p6qA02 3.30.70.330 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain 0.52 38.0 3.92e-01 79.3% 100.0%
3cvoA00 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.51 40.0 3.21e-01 90.2% 86.1%
ECOD (71)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3285944 5067.1.1.4 alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › MMPL 0.72 54.0 3.16e-01 79.3% 12.4%
3278261 304.28.1.13 a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain › MMPL 0.70 50.0 4.12e-01 74.4% 67.6%
3962574 5067.1.1.0 alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain 0.69 52.0 3.22e-01 79.3% 21.5%
5037711 304.120.1.0 a+b two layers › Alpha-beta plaits › Ferredoxin-like domain in ThiI › Ferredoxin-like domain in ThiI 0.68 48.0 5.24e-01 74.4% 96.9%
5038078 304.20.1.4 a+b two layers › Alpha-beta plaits › PAP/Archaeal CCA-adding enzyme, C-terminal domain › PAP/Archaeal CCA-adding enzyme, C-terminal domain › CAA_C 0.67 47.0 4.02e-01 73.2% 88.1%
3963055 5067.1.1.4 alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › MMPL 0.66 49.0 2.92e-01 78.0% 21.0%
4196230 304.28.1.0 a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain 0.66 47.0 4.76e-01 74.4% 91.3%
4971475 304.7.1.0 a+b two layers › Alpha-beta plaits › Protease propeptides/inhibitors › Protease propeptides/inhibitors 0.66 57.0 5.76e-01 100.0% 98.8%
3265942 304.48.1.1 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › RVT_1 0.66 47.0 3.71e-01 75.6% 62.9%
3080544 887.1.1.1 a+b two layers › Ribosomal protein L30p/L7e › Ribosomal protein L30p/L7e › Ribosomal protein L30p/L7e › Ribosomal_L30 0.65 51.0 4.86e-01 100.0% 72.0%
4647651 304.9.1.0 a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD 0.65 45.0 4.06e-01 74.4% 65.0%
5006888 304.22.1.2 a+b two layers › Alpha-beta plaits › Urease metallochaperone UreE, C-terminal domain › Urease metallochaperone UreE, C-terminal domain › PF26257 0.65 48.0 5.14e-01 78.0% 92.9%
5270 304.8.1.5 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like › NIL 0.64 47.0 4.50e-01 78.0% 84.2%
4502075 304.117.1.1 a+b two layers › Alpha-beta plaits › Ferredoxin-like domain in YebC › Ferredoxin-like domain in YebC › Transcrip_reg 0.64 45.0 4.83e-01 79.3% 87.1%
3287709 304.7.1.0 a+b two layers › Alpha-beta plaits › Protease propeptides/inhibitors › Protease propeptides/inhibitors 0.64 44.0 4.83e-01 73.2% 96.9%
4826592 2498.2.1.0 mixed a+b and a/b › Zincin-like › beta-N-acetylhexosaminidase-like domain › beta-N-acetylhexosaminidase-like domain 0.63 47.0 4.43e-01 79.3% 67.0%
4646162 304.7.1.0 a+b two layers › Alpha-beta plaits › Protease propeptides/inhibitors › Protease propeptides/inhibitors 0.63 45.0 4.95e-01 75.6% 96.9%
5077051 304.24.1.0 a+b two layers › Alpha-beta plaits › EF-G C-terminal domain-like › EF-G C-terminal domain-like 0.63 46.0 4.41e-01 79.3% 67.4%
4046774 887.1.1.1 a+b two layers › Ribosomal protein L30p/L7e › Ribosomal protein L30p/L7e › Ribosomal protein L30p/L7e › Ribosomal_L30 0.62 43.0 4.78e-01 79.3% 98.3%
4604816 887.1.1.1 a+b two layers › Ribosomal protein L30p/L7e › Ribosomal protein L30p/L7e › Ribosomal protein L30p/L7e › Ribosomal_L30 0.62 42.0 4.77e-01 78.0% 100.0%
4038263 887.1.1.1 a+b two layers › Ribosomal protein L30p/L7e › Ribosomal protein L30p/L7e › Ribosomal protein L30p/L7e › Ribosomal_L30 0.62 43.0 4.77e-01 79.3% 100.0%
1518821 304.7.1.8 a+b two layers › Alpha-beta plaits › Protease propeptides/inhibitors › Protease propeptides/inhibitors › ORF_2_N 0.62 48.0 4.11e-01 82.9% 52.3%
4013619 887.1.1.0 a+b two layers › Ribosomal protein L30p/L7e › Ribosomal protein L30p/L7e › Ribosomal protein L30p/L7e 0.62 43.0 4.34e-01 78.0% 73.8%
4599941 887.1.1.0 a+b two layers › Ribosomal protein L30p/L7e › Ribosomal protein L30p/L7e › Ribosomal protein L30p/L7e 0.62 42.0 4.72e-01 78.0% 98.3%
3959456 5067.1.1.4 alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › MMPL 0.62 48.0 3.17e-01 85.4% 32.5%
3195461 887.1.1.1 a+b two layers › Ribosomal protein L30p/L7e › Ribosomal protein L30p/L7e › Ribosomal protein L30p/L7e › Ribosomal_L30 0.62 43.0 4.10e-01 78.0% 62.1%
4960543 304.163.1.0 a+b two layers › Alpha-beta plaits › ATP-binding protein TM_1403 insertion domain › ATP-binding protein TM_1403 insertion domain 0.62 42.0 4.74e-01 78.0% 98.3%
3684485 887.1.1.1 a+b two layers › Ribosomal protein L30p/L7e › Ribosomal protein L30p/L7e › Ribosomal protein L30p/L7e › Ribosomal_L30 0.62 43.0 4.24e-01 89.0% 67.8%
4260605 304.56.1.2 a+b two layers › Alpha-beta plaits › CRISPR associated protein Cas2-like › CRISPR associated protein Cas2-like › CRISPR_Cas2 0.61 45.0 4.39e-01 79.3% 73.1%
4129069 887.1.1.1 a+b two layers › Ribosomal protein L30p/L7e › Ribosomal protein L30p/L7e › Ribosomal protein L30p/L7e › Ribosomal_L30 0.61 42.0 4.31e-01 79.3% 74.7%
4568363 304.1.1.1 a+b two layers › Alpha-beta plaits › GHMP Kinase, C-terminal domain › GHMP Kinase, C-terminal domain › GHMP_kinases_C 0.61 44.0 3.86e-01 75.6% 96.8%
3963438 304.15.1.0 a+b two layers › Alpha-beta plaits › Viral DNA-binding domain › Viral DNA-binding domain 0.61 44.0 4.78e-01 78.0% 96.9%
4074028 887.1.1.1 a+b two layers › Ribosomal protein L30p/L7e › Ribosomal protein L30p/L7e › Ribosomal protein L30p/L7e › Ribosomal_L30 0.61 43.0 4.62e-01 79.3% 92.3%
5004165 304.3.1.0 a+b two layers › Alpha-beta plaits › HMA-related › HMA, heavy metal-associated domain 0.61 45.0 4.74e-01 78.0% 94.3%
3259891 304.9.1.1 a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › RRM_1 0.61 42.0 4.24e-01 73.2% 81.2%
2774914 887.1.1.1 a+b two layers › Ribosomal protein L30p/L7e › Ribosomal protein L30p/L7e › Ribosomal protein L30p/L7e › Ribosomal_L30 0.61 41.0 3.90e-01 78.0% 57.4%
5068619 205.1.1.1 a+b two layers › 4Fe-4S ferredoxin › 4Fe-4S ferredoxin › 4Fe-4S ferredoxin › Fer4 0.60 41.0 4.61e-01 76.8% 100.0%
3897640 304.9.1.18 a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › Tap-RNA_bind 0.60 47.0 4.62e-01 84.1% 93.3%
5037704 304.8.1.0 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like 0.60 44.0 4.63e-01 79.3% 97.3%
3783820 887.1.1.1 a+b two layers › Ribosomal protein L30p/L7e › Ribosomal protein L30p/L7e › Ribosomal protein L30p/L7e › Ribosomal_L30 0.60 42.0 4.17e-01 79.3% 70.6%
4988867 304.120.1.0 a+b two layers › Alpha-beta plaits › Ferredoxin-like domain in ThiI › Ferredoxin-like domain in ThiI 0.60 43.0 4.71e-01 79.3% 96.9%
3243697 304.9.1.1 a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › RRM_1 0.60 45.0 4.27e-01 79.3% 96.8%
4971880 304.6.1.1 a+b two layers › Alpha-beta plaits › FAD-linked oxidases, C-terminal domain › FAD-linked oxidases, C-terminal domain › FAD-oxidase_C 0.60 45.0 3.28e-01 81.7% 42.1%
5048812 304.6.1.1 a+b two layers › Alpha-beta plaits › FAD-linked oxidases, C-terminal domain › FAD-linked oxidases, C-terminal domain › FAD-oxidase_C 0.60 43.0 3.09e-01 78.0% 35.6%
3653322 4113.1.1.1 beta barrels › VC0467-like › VC0467-like › VC0467-like › DUF179 0.59 49.0 3.68e-01 93.9% 42.7%
5015541 205.1.1.22 a+b two layers › 4Fe-4S ferredoxin › 4Fe-4S ferredoxin › 4Fe-4S ferredoxin › Fer4_21 0.59 41.0 4.25e-01 78.0% 80.0%
4251588 887.1.1.1 a+b two layers › Ribosomal protein L30p/L7e › Ribosomal protein L30p/L7e › Ribosomal protein L30p/L7e › Ribosomal_L30 0.59 41.0 4.44e-01 79.3% 95.2%
4034033 304.28.1.13 a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain › MMPL 0.58 51.0 4.13e-01 100.0% 83.0%
1759006 887.1.1.1 a+b two layers › Ribosomal protein L30p/L7e › Ribosomal protein L30p/L7e › Ribosomal protein L30p/L7e › Ribosomal_L30 0.58 40.0 4.42e-01 76.8% 100.0%
4205556 205.1.1.39 a+b two layers › 4Fe-4S ferredoxin › 4Fe-4S ferredoxin › 4Fe-4S ferredoxin › Fer4, Fer4_21 0.58 42.0 4.06e-01 85.4% 67.7%
3453388 304.9.1.1 a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › RRM_1 0.58 43.0 4.15e-01 79.3% 90.5%
4977851 205.1.1.22 a+b two layers › 4Fe-4S ferredoxin › 4Fe-4S ferredoxin › 4Fe-4S ferredoxin › Fer4_21 0.58 41.0 4.14e-01 81.7% 72.9%
4145835 205.1.1.39 a+b two layers › 4Fe-4S ferredoxin › 4Fe-4S ferredoxin › 4Fe-4S ferredoxin › Fer4, Fer4_21 0.58 42.0 4.25e-01 86.6% 76.5%
4384275 305.1.1.1 a+b two layers › DCoH-like › RBP11-like subunits of RNA polymerase › RBP11-like subunits of RNA polymerase › RNA_pol_L 0.58 43.0 3.53e-01 79.3% 44.8%
4028233 887.1.1.0 a+b two layers › Ribosomal protein L30p/L7e › Ribosomal protein L30p/L7e › Ribosomal protein L30p/L7e 0.58 44.0 3.37e-01 98.8% 33.3%
5026942 205.1.1.16 a+b two layers › 4Fe-4S ferredoxin › 4Fe-4S ferredoxin › 4Fe-4S ferredoxin › Fer4_7 0.57 40.0 4.34e-01 78.0% 93.8%
4205471 205.1.1.22 a+b two layers › 4Fe-4S ferredoxin › 4Fe-4S ferredoxin › 4Fe-4S ferredoxin › Fer4_21 0.57 42.0 4.10e-01 87.8% 72.2%
4206419 205.1.1.39 a+b two layers › 4Fe-4S ferredoxin › 4Fe-4S ferredoxin › 4Fe-4S ferredoxin › Fer4, Fer4_21 0.57 39.0 4.17e-01 82.9% 85.7%
4418041 2006.1.1.11 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › HAD-like › Hydrolase_3 0.56 39.0 2.72e-01 73.2% 27.6%
161738 304.9.1.1 a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › RRM_1 0.56 42.0 3.79e-01 80.5% 72.2%
3955789 304.28.1.13 a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain › MMPL 0.56 48.0 3.03e-01 100.0% 63.1%
4539039 305.1.1.1 a+b two layers › DCoH-like › RBP11-like subunits of RNA polymerase › RBP11-like subunits of RNA polymerase › RNA_pol_L 0.55 41.0 3.55e-01 82.9% 48.9%
3232200 11.1.5.37 beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Common fold of diphtheria toxin/transcription factors/cytochrome f › muHD 0.55 46.0 3.87e-01 100.0% 88.7%
3479779 887.1.1.0 a+b two layers › Ribosomal protein L30p/L7e › Ribosomal protein L30p/L7e › Ribosomal protein L30p/L7e 0.54 43.0 3.92e-01 89.0% 78.3%
4834258 205.1.1.20 a+b two layers › 4Fe-4S ferredoxin › 4Fe-4S ferredoxin › 4Fe-4S ferredoxin › Fer4_15 0.54 40.0 4.26e-01 85.4% 97.1%
4072642 304.28.1.0 a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain 0.54 46.0 3.84e-01 100.0% 87.1%
3336783 304.5.1.0 a+b two layers › Alpha-beta plaits › GlnB-like › GlnB-like 0.53 37.0 3.87e-01 78.0% 82.7%
3273120 304.9.1.1 a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › RRM_1 0.52 43.0 4.01e-01 97.6% 91.8%
3230414 887.1.1.0 a+b two layers › Ribosomal protein L30p/L7e › Ribosomal protein L30p/L7e › Ribosomal protein L30p/L7e 0.52 43.0 3.97e-01 96.3% 69.0%
3612289 304.9.1.1 a+b two layers › Alpha-beta plaits › RNA-binding domain, RBD › RNA-binding domain, RBD › RRM_1 0.52 45.0 3.90e-01 98.8% 78.5%
3973910 3016.1.1.19 a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › KYNU_C 0.52 43.0 3.92e-01 92.7% 72.7%
D3 medium residues 48-204
PDB
Domain cluster: representative
CATH (15)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4qboA00 3.40.1350.10 Alpha Beta › 3-Layer(aba) Sandwich › Trna Endonuclease; Chain: A, domain 1 › 0.68 40.0 4.95e-01 95.5% 96.7%
1ob8A00 3.40.1350.10 Alpha Beta › 3-Layer(aba) Sandwich › Trna Endonuclease; Chain: A, domain 1 › 0.63 46.0 5.20e-01 97.5% 99.2%
1luiA00 3.30.505.10 Alpha Beta › 2-Layer Sandwich › SHC Adaptor Protein › SH2 domain 0.62 40.0 4.72e-01 95.5% 93.5%
2eo0B00 3.40.1350.10 Alpha Beta › 3-Layer(aba) Sandwich › Trna Endonuclease; Chain: A, domain 1 › 0.60 45.0 4.96e-01 98.1% 97.6%
3jtzA00 3.30.160.390 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Integrase, DNA-binding domain 0.60 30.0 4.00e-01 93.0% 93.5%
1xmxA02 3.40.1350.10 Alpha Beta › 3-Layer(aba) Sandwich › Trna Endonuclease; Chain: A, domain 1 › 0.59 47.0 4.81e-01 94.3% 87.9%
6p4wB01 3.40.91.30 Alpha Beta › 3-Layer(aba) Sandwich › Restriction Endonuclease › 0.58 40.0 4.63e-01 94.9% 100.0%
6mzoA01 3.40.50.11970 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › 0.58 35.0 3.89e-01 73.2% 74.6%
2p14A00 3.40.91.50 Alpha Beta › 3-Layer(aba) Sandwich › Restriction Endonuclease › 0.55 48.0 4.57e-01 100.0% 80.6%
2ewfA03 3.40.91.50 Alpha Beta › 3-Layer(aba) Sandwich › Restriction Endonuclease › 0.54 50.0 4.41e-01 100.0% 72.4%
1imuA00 3.30.160.100 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Ribosome hibernation promotion factor-like 0.54 28.0 3.36e-01 98.1% 72.0%
2rqlA00 3.30.160.100 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Ribosome hibernation promotion factor-like 0.52 27.0 3.34e-01 95.5% 80.0%
3tqmA00 3.30.160.100 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Ribosome hibernation promotion factor-like 0.51 27.0 3.33e-01 97.5% 83.3%
1rznA00 3.40.1350.10 Alpha Beta › 3-Layer(aba) Sandwich › Trna Endonuclease; Chain: A, domain 1 › 0.51 44.0 4.55e-01 96.8% 100.0%
1iqoA00 3.30.160.120 Alpha Beta › 2-Layer Sandwich › Double Stranded RNA Binding Domain › Hypothetical protein MTH1880 0.50 25.0 3.22e-01 74.5% 83.0%
ECOD (35)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3604467 2008.1.1.0 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like 0.80 75.0 6.67e-01 100.0% 73.3%
5012636 2008.1.1.15 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › HSDR_N 0.76 65.0 6.05e-01 100.0% 74.1%
4150493 2008.1.1.0 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like 0.72 60.0 5.32e-01 94.9% 62.6%
3723542 2008.1.1.0 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like 0.72 43.0 4.85e-01 72.0% 75.6%
3207613 2008.1.1.0 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like 0.72 51.0 5.10e-01 99.4% 69.9%
3838862 2008.1.1.0 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like 0.72 60.0 6.09e-01 94.9% 88.4%
4222489 2008.1.1.0 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like 0.69 47.0 5.44e-01 100.0% 98.2%
4955243 2008.1.1.0 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like 0.65 46.0 4.40e-01 96.8% 62.2%
4942427 2008.1.1.0 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like 0.64 43.0 5.04e-01 100.0% 100.0%
3209857 2008.1.1.143 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › DUF7924 0.62 48.0 4.59e-01 97.5% 69.4%
3182836 2008.1.1.0 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like 0.61 56.0 5.47e-01 98.7% 90.6%
4149106 2008.1.1.3 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › Hjc 0.61 46.0 4.98e-01 98.1% 92.6%
4978721 2008.1.1.0 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like 0.60 41.0 4.76e-01 72.6% 95.7%
4234615 330.4.1.0 a+b two layers › dsRBD-like › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain › Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain 0.60 30.0 4.03e-01 97.5% 96.0%
5063644 2008.1.1.141 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › PDDEXK_19 0.59 41.0 4.67e-01 95.5% 96.5%
4384457 2008.1.1.3 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › Hjc 0.59 47.0 5.08e-01 100.0% 100.0%
4932472 319.1.1.1 beta sandwiches › HSP20-like › HSP20-like chaperones › HSP20-like chaperones › HSP20 0.59 24.0 2.95e-01 73.9% 55.8%
4957244 2008.1.1.0 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like 0.59 39.0 4.57e-01 91.7% 99.0%
4940109 2008.1.1.3 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › Hjc 0.59 43.0 4.79e-01 91.1% 96.7%
4941226 2008.1.1.0 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like 0.58 39.0 4.28e-01 94.9% 82.9%
4942264 2008.1.1.3 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › Hjc 0.58 44.0 4.83e-01 95.5% 98.4%
5057728 2008.1.1.0 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like 0.57 43.0 4.74e-01 98.7% 100.0%
3386971 3675.1.1.0 a+b complex topology › DNA gyrase subunit B insertion domain › DNA gyrase subunit B insertion domain › DNA gyrase subunit B insertion domain 0.55 29.0 3.16e-01 87.3% 58.5%
5043832 2008.1.1.0 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like 0.55 40.0 4.42e-01 98.7% 97.5%
3408369 284.1.3.4 a+b two layers › FKBP-like › FKBP-like › WNK1 autoinhibitory domain › CCTL2_WNK 0.55 22.0 3.08e-01 82.2% 73.3%
198173 2008.1.1.45 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › RE_AlwI 0.55 48.0 4.57e-01 100.0% 80.6%
3837990 3675.1.1.0 a+b complex topology › DNA gyrase subunit B insertion domain › DNA gyrase subunit B insertion domain › DNA gyrase subunit B insertion domain 0.54 29.0 3.16e-01 87.3% 60.0%
3739965 298.1.1.0 a+b two layers › FwdE/GAPDH domain-like › Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain › Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain 0.54 49.0 3.71e-01 100.0% 91.7%
5049398 2008.1.1.0 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like 0.53 40.0 4.11e-01 86.0% 80.7%
4032015 296.1.1.1 a+b three layers › Sulfite reductase hemoprotein (SiRHP), domains 2 and 4 › Sulfite reductase hemoprotein (SiRHP), domains 2 and 4 › Sulfite reductase hemoprotein (SiRHP), domains 2 and 4 › NIR_SIR 0.53 38.0 3.90e-01 100.0% 77.3%
4989011 2008.1.1.3 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › Hjc 0.52 45.0 4.64e-01 93.0% 100.0%
3237889 7504.1.1.0 a/b three-layered sandwiches › ITPase-like › ITPase-like › ITPase-like 0.52 42.0 4.00e-01 86.0% 93.5%
4357158 2008.1.1.13 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › RecU 0.51 43.0 4.20e-01 94.9% 81.7%
1144868 2008.1.1.66 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › ArenaCapSnatch 0.50 37.0 3.62e-01 77.1% 69.8%
5044629 223.2.1.0 a+b three layers › Profilin-like › profilin-like › profilin-like 0.50 35.0 3.96e-01 98.7% 98.3%
D4 medium residues 402-493
PDB
Domain cluster: representative
CATH (22)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2f8lA01 1.10.150.470 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › 0.70 43.0 4.53e-01 76.1% 69.1%
2ahoB02 1.10.150.190 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Translation initiation factor 2; subunit 1; domain 2 0.69 50.0 5.07e-01 76.1% 97.8%
2fi1A02 1.10.150.240 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Putative phosphatase; domain 2 0.65 43.0 4.98e-01 80.4% 98.4%
2a6hF01 1.20.120.1810 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.63 44.0 3.52e-01 71.7% 40.4%
3ousA00 1.10.287.70 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.63 41.0 4.31e-01 84.8% 74.4%
3otdA00 3.30.70.3000 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › tRNA(His) guanylyltransferase (Thg1) 0.61 55.0 4.06e-01 100.0% 80.8%
3fseB02 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.61 46.0 3.99e-01 80.4% 66.0%
2ahrA02 1.10.3730.10 Mainly Alpha › Orthogonal Bundle › ProC C-terminal domain-like fold › ProC C-terminal domain-like 0.60 50.0 4.83e-01 92.4% 97.2%
2om6A02 1.10.150.400 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › 0.60 42.0 4.53e-01 72.8% 100.0%
5zzjA02 1.10.600.10 Mainly Alpha › Orthogonal Bundle › Farnesyl Diphosphate Synthase › Farnesyl Diphosphate Synthase 0.59 49.0 3.44e-01 91.3% 42.4%
3cymA03 1.10.150.80 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › HRDC domain 0.59 44.0 4.48e-01 78.3% 90.9%
4gr2A00 1.10.1200.210 Mainly Alpha › Orthogonal Bundle › Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A › Chaperonin-like RbcX 0.59 48.0 4.55e-01 90.2% 79.1%
3r2cA00 1.10.940.10 Mainly Alpha › Orthogonal Bundle › N-utilizing Substance Protein B Homolog; Chain A › NusB-like 0.56 39.0 3.41e-01 72.8% 78.3%
3kv0A01 1.10.3520.10 Mainly Alpha › Orthogonal Bundle › Glycolipid transfer protein, GLTP › Glycolipid transfer protein 0.55 44.0 3.56e-01 84.8% 59.4%
3rh9A01 3.40.605.10 Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 1 › Aldehyde Dehydrogenase; Chain A, domain 1 0.55 40.0 2.92e-01 79.3% 45.3%
2hg2A01 3.40.605.10 Alpha Beta › 3-Layer(aba) Sandwich › Aldehyde Dehydrogenase; Chain A, domain 1 › Aldehyde Dehydrogenase; Chain A, domain 1 0.54 39.0 2.86e-01 78.3% 45.8%
2qvwA04 1.10.1520.10 Mainly Alpha › Orthogonal Bundle › Ribonuclease iii, N-terminal Endonuclease Domain; Chain A › Ribonuclease III domain 0.53 45.0 3.83e-01 90.2% 68.3%
3um7A03 1.10.287.70 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.52 40.0 3.93e-01 94.6% 74.8%
1xaiA02 1.20.1090.10 Mainly Alpha › Up-down Bundle › Dehydroquinate synthase-like, alpha domain › Dehydroquinate synthase-like - alpha domain 0.52 41.0 3.28e-01 84.8% 46.8%
4oogC01 1.10.1520.10 Mainly Alpha › Orthogonal Bundle › Ribonuclease iii, N-terminal Endonuclease Domain; Chain A › Ribonuclease III domain 0.51 41.0 3.43e-01 87.0% 69.8%
7r97A01 1.10.1520.10 Mainly Alpha › Orthogonal Bundle › Ribonuclease iii, N-terminal Endonuclease Domain; Chain A › Ribonuclease III domain 0.51 40.0 3.53e-01 87.0% 59.5%
3c24A02 1.10.3640.10 Mainly Alpha › Orthogonal Bundle › putative oxidoreductase fold › Semialdehyde dehydrogenase-like, C-terminal 0.50 41.0 4.03e-01 92.4% 93.0%
ECOD (22)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4142281 105.1.1.55 alpha duplicates or obligate multimers › HLH-like › HLH, helix-loop-helix DNA-binding domain › HLH, helix-loop-helix DNA-binding domain › Latarcin 0.72 48.0 4.78e-01 75.0% 66.0%
5043111 3542.1.1.2 alpha arrays › Presenilin family intramembrane aspartate proteases › Presenilin family intramembrane aspartate proteases › Presenilin family intramembrane aspartate proteases › SPP 0.63 46.0 3.36e-01 76.1% 52.4%
4973231 304.48.1.20 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › Thg1 0.62 54.0 3.99e-01 95.7% 49.6%
3587994 3962.1.1.0 alpha arrays › N-terminal helical domain in restriction-modification system methylation subunit-like › N-terminal helical domain in restriction-modification system methylation subunit › N-terminal helical domain in restriction-modification system methylation subunit 0.62 38.0 4.30e-01 79.3% 81.4%
5074147 304.48.1.20 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like › Thg1 0.62 54.0 4.04e-01 96.7% 56.1%
5024662 138.1.1.0 alpha arrays › DNA polymerase III clamp loader subunits, C-terminal domain › DNA polymerase III clamp loader subunits, C-terminal domain › DNA polymerase III clamp loader subunits, C-terminal domain 0.62 42.0 3.41e-01 82.6% 36.6%
5024487 842.1.1.1 a+b two layers › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thymidylate synthase-complementing protein Thy1 › Thy1 0.61 43.0 3.34e-01 76.1% 32.4%
5031862 304.48.1.0 a+b two layers › Alpha-beta plaits › Adenylyl and guanylyl cyclase catalytic domain-like › Adenylyl and guanylyl cyclase catalytic domain-like 0.61 54.0 4.42e-01 98.9% 72.9%
4524416 5054.1.1.8 alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › Ion_trans_2 0.60 40.0 3.86e-01 83.7% 60.0%
5051162 633.12.1.0 alpha bundles › Bromodomain-like › Ta0600-like › Ta0600-like 0.59 43.0 4.43e-01 76.1% 89.4%
5043797 3542.1.1.1 alpha arrays › Presenilin family intramembrane aspartate proteases › Presenilin family intramembrane aspartate proteases › Presenilin family intramembrane aspartate proteases › Presenilin 0.59 46.0 3.27e-01 82.6% 32.4%
5014397 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.58 45.0 3.68e-01 85.9% 84.2%
2324073 102.1.1.111 alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › SAM domain-like › PF31229 0.58 35.0 3.94e-01 72.8% 81.2%
5042339 5065.1.1.1 alpha bundles › Type II ABC importer transmembrane domain fold › Type II ABC importer transmembrane domain fold › Type II ABC importer transmembrane domain fold › ABC-3 0.57 44.0 3.24e-01 83.7% 90.2%
4259065 103.4.1.0 alpha arrays › RuvA-C › Elongation factor TFIIS domain 2/ Kix domain of creb binding protein › Elongation factor TFIIS domain 2/ Kix domain of creb binding protein 0.57 39.0 4.22e-01 70.7% 100.0%
4996618 131.1.1.0 alpha complex topology › PDEase-like › HD-domain/PDEase-like › HD-domain/PDEase-like 0.56 45.0 2.95e-01 90.2% 35.0%
3926333 5054.1.1.59 alpha complex topology › Voltage-gated ion channels › Voltage-gated ion channels › Voltage-gated ion channels › Ion_trans, Ion_trans_2 0.55 43.0 2.86e-01 83.7% 21.6%
4029621 5081.1.1.1 alpha bundles › Rhomboid-like › Rhomboid-like › Rhomboid-like › Rhomboid 0.55 40.0 3.06e-01 76.1% 55.3%
3596737 604.8.1.0 alpha bundles › Spectrin repeat-like › Smac/diablo › Smac/diablo 0.54 40.0 3.54e-01 77.2% 83.8%
4954779 5065.1.1.1 alpha bundles › Type II ABC importer transmembrane domain fold › Type II ABC importer transmembrane domain fold › Type II ABC importer transmembrane domain fold › ABC-3 0.54 42.0 3.15e-01 87.0% 89.4%
3928768 3542.1.1.3 alpha arrays › Presenilin family intramembrane aspartate proteases › Presenilin family intramembrane aspartate proteases › Presenilin family intramembrane aspartate proteases › Peptidase_A22B 0.53 42.0 2.99e-01 88.0% 63.2%
4579424 2003.1.1.0 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › NAD(P)-binding Rossmann-fold domains 0.50 40.0 3.02e-01 87.0% 44.6%
D5 medium residues 494-545_569-585
PDB
Domain cluster: representative
CATH (15)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
6e5bN00 3.60.20.10 Alpha Beta › 4-Layer Sandwich › Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1 › Aminohydrolase, N-terminal nucleophile (Ntn) domain 0.72 58.0 4.13e-01 87.0% 47.7%
6muwB00 3.60.20.10 Alpha Beta › 4-Layer Sandwich › Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1 › Aminohydrolase, N-terminal nucleophile (Ntn) domain 0.69 56.0 3.83e-01 87.0% 55.0%
5fmgG00 3.60.20.10 Alpha Beta › 4-Layer Sandwich › Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1 › Aminohydrolase, N-terminal nucleophile (Ntn) domain 0.69 55.0 3.87e-01 87.0% 56.6%
3unbF00 3.60.20.10 Alpha Beta › 4-Layer Sandwich › Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1 › Aminohydrolase, N-terminal nucleophile (Ntn) domain 0.68 55.0 3.74e-01 88.4% 53.3%
5fmgA00 3.60.20.10 Alpha Beta › 4-Layer Sandwich › Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1 › Aminohydrolase, N-terminal nucleophile (Ntn) domain 0.67 55.0 3.84e-01 88.4% 58.4%
8f66A01 3.60.20.10 Alpha Beta › 4-Layer Sandwich › Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1 › Aminohydrolase, N-terminal nucleophile (Ntn) domain 0.66 54.0 3.80e-01 88.4% 61.4%
1iruI00 3.60.20.10 Alpha Beta › 4-Layer Sandwich › Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1 › Aminohydrolase, N-terminal nucleophile (Ntn) domain 0.66 52.0 3.69e-01 87.0% 43.2%
5fmgF00 3.60.20.10 Alpha Beta › 4-Layer Sandwich › Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1 › Aminohydrolase, N-terminal nucleophile (Ntn) domain 0.65 52.0 3.69e-01 88.4% 57.5%
1rypA00 3.60.20.10 Alpha Beta › 4-Layer Sandwich › Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1 › Aminohydrolase, N-terminal nucleophile (Ntn) domain 0.64 52.0 3.57e-01 88.4% 53.5%
1rktA01 1.10.10.60 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Homeodomain-like 0.64 41.0 4.54e-01 84.1% 86.8%
2opeA00 3.30.540.20 Alpha Beta › 2-Layer Sandwich › Fructose-1,6-Bisphosphatase; Chain A, domain 1 › 0.63 46.0 3.90e-01 95.7% 45.8%
3ke6B01 3.60.40.10 Alpha Beta › 4-Layer Sandwich › Phosphatase 2c; domain 1 › PPM-type phosphatase domain 0.58 41.0 2.94e-01 75.4% 43.4%
4hyqA00 3.40.50.1110 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › SGNH hydrolase 0.58 40.0 2.81e-01 94.2% 21.2%
1x3zA03 1.10.1740.90 Mainly Alpha › Orthogonal Bundle › Rna Polymerase Sigma Factor; Chain: A › 0.57 47.0 4.33e-01 89.9% 79.5%
2reoA01 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.51 41.0 2.96e-01 89.9% 75.4%
ECOD (16)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
2980420 210.1.1.2 a+b four layers › Ntn/PP2C › Ntn › Proteasome subunits › Proteasome,Proteasome_A_N 0.69 56.0 3.91e-01 88.4% 57.1%
3438106 210.1.1.2 a+b four layers › Ntn/PP2C › Ntn › Proteasome subunits › Proteasome,Proteasome_A_N 0.68 55.0 3.73e-01 88.4% 51.8%
3558294 210.1.1.1 a+b four layers › Ntn/PP2C › Ntn › Proteasome subunits › Proteasome 0.67 54.0 3.73e-01 88.4% 55.3%
4023842 210.1.1.2 a+b four layers › Ntn/PP2C › Ntn › Proteasome subunits › Proteasome,Proteasome_A_N 0.66 54.0 3.63e-01 88.4% 53.3%
5014874 210.1.1.1 a+b four layers › Ntn/PP2C › Ntn › Proteasome subunits › Proteasome 0.66 53.0 3.62e-01 88.4% 50.2%
4928312 210.1.1.1 a+b four layers › Ntn/PP2C › Ntn › Proteasome subunits › Proteasome 0.66 53.0 3.83e-01 88.4% 64.6%
3403944 210.1.1.2 a+b four layers › Ntn/PP2C › Ntn › Proteasome subunits › Proteasome,Proteasome_A_N 0.66 53.0 3.61e-01 88.4% 52.0%
5060317 210.1.1.1 a+b four layers › Ntn/PP2C › Ntn › Proteasome subunits › Proteasome 0.63 51.0 3.57e-01 88.4% 57.3%
3999390 210.1.1.1 a+b four layers › Ntn/PP2C › Ntn › Proteasome subunits › Proteasome 0.63 50.0 3.49e-01 88.4% 56.2%
3405593 210.1.1.1 a+b four layers › Ntn/PP2C › Ntn › Proteasome subunits › Proteasome 0.61 48.0 3.67e-01 84.1% 41.9%
3797631 210.1.1.0 a+b four layers › Ntn/PP2C › Ntn › Proteasome subunits 0.61 51.0 3.58e-01 95.7% 56.8%
3234712 102.1.3.6 alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › PAP/OAS1 substrate-binding domain › Nrap_D2 0.61 47.0 3.73e-01 82.6% 54.8%
5050853 2004.1.1.16 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › Arf 0.58 49.0 3.30e-01 95.7% 42.2%
4217957 219.1.1.79 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Transglut_core2 0.57 42.0 3.24e-01 79.7% 72.1%
3673570 149.1.1.1 alpha arrays › Cytochrome P450 › Cytochrome P450 › Cytochrome P450 › p450 0.55 48.0 3.16e-01 97.1% 45.0%
5008694 219.1.1.13 a+b complex topology › Cysteine proteinases-like › Cysteine proteinases › Cysteine proteinases › Transglut_core 0.55 42.0 3.06e-01 81.2% 76.3%
D6 medium residues 839-956
PDB
Domain cluster: representative
CATH (1)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3ufbA02 3.40.50.150 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › Vaccinia Virus protein VP39 0.62 55.0 4.01e-01 97.5% 38.8%
ECOD (8)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
5080533 2003.1.5.62 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Eco57I 0.90 77.0 5.29e-01 98.3% 30.1%
3388298 2003.1.5.62 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Eco57I 0.71 53.0 3.68e-01 85.6% 24.5%
4565957 2003.1.5.22 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › N6_Mtase 0.71 51.0 3.87e-01 84.7% 33.2%
3981664 2003.1.5.160 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › N6_Mtase, Eco57I 0.68 55.0 3.71e-01 98.3% 23.8%
4954651 2003.1.5.62 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Eco57I 0.67 50.0 4.50e-01 85.6% 56.4%
4948425 2003.1.5.22 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › N6_Mtase 0.67 47.0 4.01e-01 92.4% 46.9%
5065151 2003.1.5.22 a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › N6_Mtase 0.61 48.0 3.33e-01 84.7% 25.7%
3960924 323.1.1.9 a+b complex topology › CoA-dependent acyltransferases › CoA-dependent acyltransferases › CoA-dependent acyltransferases › WS_DGAT_cat,WS_DGAT_C 0.50 40.0 2.74e-01 86.4% 79.5%
D7 medium residues 957-1147
PDB
Domain cluster: representative
CATH (5)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1t3dA01 1.10.3130.10 Mainly Alpha › Orthogonal Bundle › serine acetyltransferase, domain 1 › serine acetyltransferase, domain 1 0.58 40.0 4.60e-01 82.2% 97.1%
2z1qB04 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.54 32.0 3.72e-01 79.1% 80.1%
2jaeA03 1.20.1440.240 Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 0.54 19.0 2.60e-01 83.8% 57.4%
4rm7A03 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.54 36.0 4.08e-01 80.6% 91.4%
2y39A00 1.20.120.1490 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › 0.51 30.0 3.78e-01 75.9% 100.0%
ECOD (9)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4999709 4333.1.1.0 a+b complex topology › DNA methylase specificity domain › DNA methylase specificity domain › DNA methylase specificity domain 0.74 62.0 5.32e-01 85.9% 96.1%
5012794 4333.1.1.0 a+b complex topology › DNA methylase specificity domain › DNA methylase specificity domain › DNA methylase specificity domain 0.73 63.0 5.06e-01 90.1% 97.2%
4954652 4333.1.1.0 a+b complex topology › DNA methylase specificity domain › DNA methylase specificity domain › DNA methylase specificity domain 0.73 56.0 5.00e-01 79.6% 95.8%
3385784 4333.1.1.0 a+b complex topology › DNA methylase specificity domain › DNA methylase specificity domain › DNA methylase specificity domain 0.72 63.0 5.33e-01 90.6% 93.2%
5045467 4333.1.1.2 a+b complex topology › DNA methylase specificity domain › DNA methylase specificity domain › DNA methylase specificity domain › TaqI_C 0.71 62.0 5.65e-01 90.1% 91.3%
4954642 4333.1.1.0 a+b complex topology › DNA methylase specificity domain › DNA methylase specificity domain › DNA methylase specificity domain 0.70 60.0 5.40e-01 89.5% 95.3%
3975469 4333.1.1.0 a+b complex topology › DNA methylase specificity domain › DNA methylase specificity domain › DNA methylase specificity domain 0.69 60.0 5.32e-01 89.5% 97.7%
4150867 5058.1.1.29 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › AlaE 0.55 28.0 3.86e-01 99.0% 97.9%
3280627 633.6.1.1 alpha bundles › Bromodomain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA dehydrogenase C-terminal domain-like › Acyl-CoA_dh_1 0.55 35.0 3.99e-01 79.6% 86.4%