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IMGVR_UViG_2926421783_000001-2926421783-2926423791

Arc-Vir

IMGVR_UViG_2926421783_000001-2926421783-2926423791

Identity

Kingdom:
archaea

Quality

86.9 mean pLDDT

Cluster

Singleton — not in a non-trivial cluster

3D Structure

Domains

high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.

D1 high residues 5-123_154-221
PDB
Domain cluster: representative
CATH (24)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
4bpuC00 3.90.920.10 Alpha Beta › Alpha-Beta Complex › DNA primase, PRIM domain › DNA primase, PRIM domain 0.74 69.0 5.45e-01 100.0% 95.9%
2faoA01 3.90.920.10 Alpha Beta › Alpha-Beta Complex › DNA primase, PRIM domain › DNA primase, PRIM domain 0.72 68.0 5.82e-01 100.0% 90.4%
4limA00 3.90.920.10 Alpha Beta › Alpha-Beta Complex › DNA primase, PRIM domain › DNA primase, PRIM domain 0.72 67.0 5.23e-01 100.0% 96.1%
5of3A00 3.90.920.10 Alpha Beta › Alpha-Beta Complex › DNA primase, PRIM domain › DNA primase, PRIM domain 0.70 63.0 5.19e-01 95.7% 80.3%
1g71A01 3.90.920.10 Alpha Beta › Alpha-Beta Complex › DNA primase, PRIM domain › DNA primase, PRIM domain 0.66 60.0 5.54e-01 95.7% 86.0%
3h20A02 3.30.70.1790 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RepB DNA-primase, N-terminal domain 0.64 35.0 4.64e-01 90.4% 98.1%
2xhcA01 3.30.70.940 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › NusG, N-terminal domain 0.60 31.0 4.22e-01 89.3% 96.8%
4i68A00 3.30.70.1800 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › 0.60 28.0 3.80e-01 83.4% 86.7%
2dr1A01 3.90.1150.10 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 0.58 30.0 3.51e-01 100.0% 68.1%
2rqkA00 3.30.70.260 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › ACT domain 0.58 31.0 3.95e-01 72.2% 88.1%
6c6uN00 3.30.70.940 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › NusG, N-terminal domain 0.57 31.0 4.11e-01 88.2% 99.0%
1m1hA01 3.30.70.940 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › NusG, N-terminal domain 0.57 32.0 4.13e-01 77.5% 100.0%
2atzA00 3.90.920.20 Alpha Beta › Alpha-Beta Complex › DNA primase, PRIM domain › HP0184-like 0.57 48.0 5.01e-01 97.3% 96.6%
3lwsF02 3.90.1150.10 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 0.55 30.0 3.82e-01 100.0% 92.3%
1z1dB00 3.40.1310.20 Alpha Beta › 3-Layer(aba) Sandwich › Replication Protein E1; Chain: A, › 0.55 35.0 4.09e-01 84.5% 90.8%
2if1A00 3.30.780.10 Alpha Beta › 2-Layer Sandwich › Translation Initiation Factor Eif1 › SUI1-like domain 0.55 26.0 3.05e-01 70.6% 61.9%
1zhvA00 3.30.2130.10 Alpha Beta › 2-Layer Sandwich › VC0802-like › VC0802-like 0.55 34.0 3.94e-01 75.4% 85.8%
2c2nA02 3.30.70.250 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Malonyl-CoA ACP transacylase, ACP-binding 0.54 25.0 3.57e-01 70.6% 100.0%
4mt1A02 3.30.70.1430 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Multidrug efflux transporter AcrB pore domain 0.52 30.0 3.87e-01 87.7% 100.0%
3pgvA02 3.30.1240.10 Alpha Beta › 2-Layer Sandwich › Hypothetical Protein, Haloacid Dehalogenase-like Hydrolase; Chain: A; domain 2 › 0.52 29.0 3.73e-01 84.5% 98.0%
1fjeB01 3.30.70.330 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › RRM (RNA recognition motif) domain 0.52 25.0 3.49e-01 72.7% 100.0%
5t0oA02 3.30.70.1430 Alpha Beta › 2-Layer Sandwich › Alpha-Beta Plaits › Multidrug efflux transporter AcrB pore domain 0.52 30.0 3.81e-01 79.1% 100.0%
2dgkA02 3.90.1150.160 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › 0.51 27.0 3.50e-01 87.2% 89.7%
3f0hA01 3.90.1150.10 Alpha Beta › Alpha-Beta Complex › Aspartate Aminotransferase, domain 1 › Aspartate Aminotransferase, domain 1 0.51 25.0 3.23e-01 96.3% 85.4%
ECOD (30)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
5058297 862.1.1.1 a+b complex topology › Prim-pol domain › Prim-pol domain › Prim-pol domain › DNA_primase_S 0.74 70.0 6.00e-01 100.0% 92.9%
4942021 862.1.1.5 a+b complex topology › Prim-pol domain › Prim-pol domain › Prim-pol domain › LigD_Prim-Pol 0.74 70.0 6.04e-01 100.0% 86.9%
5066297 862.1.1.5 a+b complex topology › Prim-pol domain › Prim-pol domain › Prim-pol domain › LigD_Prim-Pol 0.73 70.0 6.01e-01 100.0% 88.7%
4986859 862.1.1.5 a+b complex topology › Prim-pol domain › Prim-pol domain › Prim-pol domain › LigD_Prim-Pol 0.73 69.0 5.85e-01 100.0% 85.8%
5037338 862.1.1.1 a+b complex topology › Prim-pol domain › Prim-pol domain › Prim-pol domain › DNA_primase_S 0.73 69.0 6.06e-01 100.0% 90.9%
4960009 862.1.1.5 a+b complex topology › Prim-pol domain › Prim-pol domain › Prim-pol domain › LigD_Prim-Pol 0.73 69.0 5.88e-01 100.0% 88.4%
4937156 862.1.1.5 a+b complex topology › Prim-pol domain › Prim-pol domain › Prim-pol domain › LigD_Prim-Pol 0.73 69.0 5.92e-01 100.0% 87.5%
4987159 862.1.1.5 a+b complex topology › Prim-pol domain › Prim-pol domain › Prim-pol domain › LigD_Prim-Pol 0.73 69.0 6.08e-01 100.0% 90.4%
3604598 862.1.1.1 a+b complex topology › Prim-pol domain › Prim-pol domain › Prim-pol domain › DNA_primase_S 0.73 69.0 5.90e-01 100.0% 91.4%
3278096 862.1.1.5 a+b complex topology › Prim-pol domain › Prim-pol domain › Prim-pol domain › LigD_Prim-Pol 0.72 68.0 5.57e-01 100.0% 79.1%
5000686 862.1.1.1 a+b complex topology › Prim-pol domain › Prim-pol domain › Prim-pol domain › DNA_primase_S 0.72 65.0 5.58e-01 95.7% 94.0%
5054620 862.1.1.5 a+b complex topology › Prim-pol domain › Prim-pol domain › Prim-pol domain › LigD_Prim-Pol 0.71 67.0 6.05e-01 100.0% 86.0%
None 0.71 67.0 5.57e-01 100.0% 81.6%
None 0.71 67.0 5.55e-01 100.0% 81.3%
4955551 862.1.1.0 a+b complex topology › Prim-pol domain › Prim-pol domain › Prim-pol domain 0.71 67.0 6.04e-01 100.0% 93.5%
5029237 862.1.1.0 a+b complex topology › Prim-pol domain › Prim-pol domain › Prim-pol domain 0.71 64.0 5.81e-01 95.7% 84.5%
5026687 862.1.1.0 a+b complex topology › Prim-pol domain › Prim-pol domain › Prim-pol domain 0.71 67.0 5.78e-01 100.0% 88.7%
4984518 862.1.1.0 a+b complex topology › Prim-pol domain › Prim-pol domain › Prim-pol domain 0.70 66.0 5.74e-01 100.0% 90.7%
4998612 862.1.1.1 a+b complex topology › Prim-pol domain › Prim-pol domain › Prim-pol domain › DNA_primase_S 0.67 60.0 5.52e-01 95.2% 92.5%
5043257 304.24.1.5 a+b two layers › Alpha-beta plaits › EF-G C-terminal domain-like › EF-G C-terminal domain-like › Trm5_N 0.60 24.0 3.76e-01 83.4% 100.0%
3742864 304.8.1.0 a+b two layers › Alpha-beta plaits › ACT-like › ACT-like 0.59 29.0 3.65e-01 75.9% 76.4%
5000277 3016.1.1.0 a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases 0.58 29.0 3.96e-01 99.5% 91.8%
3381288 304.24.1.0 a+b two layers › Alpha-beta plaits › EF-G C-terminal domain-like › EF-G C-terminal domain-like 0.58 27.0 3.81e-01 89.8% 94.1%
5006953 873.1.1.12 a+b complex topology › H-NOX domain › H-NOX domain › H-NOX domain › PF27313 0.58 27.0 3.55e-01 82.9% 80.0%
4992146 304.57.1.0 a+b two layers › Alpha-beta plaits › Rpp14/Pop5-like › Rpp14/Pop5-like 0.56 28.0 3.80e-01 72.7% 96.7%
5068786 304.28.1.0 a+b two layers › Alpha-beta plaits › Ferredoxin domains in multidrug efflux transporter › Multidrug efflux transporter AcrB pore domain 0.54 28.0 3.75e-01 95.2% 96.8%
1820981 304.51.1.11 a+b two layers › Alpha-beta plaits › CRISPR transcript (pre-crRNA) processing endoribonuclease-related › CRISPR transcript (pre-crRNA) processing endoribonuclease-related › Cas6b_N 0.51 25.0 3.52e-01 93.0% 100.0%
4133554 304.24.1.21 a+b two layers › Alpha-beta plaits › EF-G C-terminal domain-like › EF-G C-terminal domain-like › EFG_C+EFG_III 0.51 28.0 2.86e-01 70.6% 52.1%
3972123 304.24.1.0 a+b two layers › Alpha-beta plaits › EF-G C-terminal domain-like › EF-G C-terminal domain-like 0.51 28.0 3.63e-01 71.1% 95.2%
1151963 3016.1.1.0 a+b two layers › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases › C-terminal domain in some PLP-dependent transferases 0.50 30.0 3.43e-01 100.0% 80.8%
D2 high residues 260-360
PDB
CATH (27)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
3h20A04 1.10.1240.50 Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › 0.71 49.0 5.23e-01 77.2% 80.9%
7zh0A01 1.20.1250.20 Mainly Alpha › Up-down Bundle › Growth Hormone; Chain: A; › MFS general substrate transporter like domains 0.65 47.0 3.12e-01 75.2% 41.7%
1n81A00 1.10.3030.10 Mainly Alpha › Orthogonal Bundle › Gametocyte protein Pfg27 › Gametocyte protein Pfg27 0.64 47.0 3.84e-01 77.2% 93.0%
3ulkA02 1.10.1040.10 Mainly Alpha › Orthogonal Bundle › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 0.64 49.0 3.56e-01 81.2% 78.6%
7qoaA01 1.10.4160.10 Mainly Alpha › Orthogonal Bundle › Hydantoin permease › Hydantoin permease 0.62 52.0 3.52e-01 93.1% 90.5%
1qmgA02 1.10.1040.10 Mainly Alpha › Orthogonal Bundle › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 › N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2 0.60 47.0 3.38e-01 83.2% 77.1%
3llkA02 1.20.120.310 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › ERV/ALR sulfhydryl oxidase domain 0.59 42.0 3.77e-01 74.3% 92.3%
1urvA00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.59 43.0 3.76e-01 76.2% 60.4%
3m9vA01 1.10.540.10 Mainly Alpha › Orthogonal Bundle › Butyryl-Coa Dehydrogenase, subunit A; domain 1 › Acyl-CoA dehydrogenase/oxidase, N-terminal domain 0.59 45.0 4.24e-01 83.2% 89.0%
1zvwA01 1.20.970.10 Mainly Alpha › Up-down Bundle › Transferase, Pyrimidine Nucleoside Phosphorylase; Chain A, domain 3 › Transferase, Pyrimidine Nucleoside Phosphorylase; Chain C 0.58 37.0 4.38e-01 71.3% 98.5%
5my3A00 1.10.555.10 Mainly Alpha › Orthogonal Bundle › Phosphatidylinositol 3-kinase; Chain A › Rho GTPase activation protein 0.58 43.0 3.50e-01 80.2% 85.0%
3ezxA01 1.10.1240.10 Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › Methionine synthase domain 0.57 41.0 4.32e-01 74.3% 93.0%
3q18A02 1.20.1050.10 Mainly Alpha › Up-down Bundle › Glutathione S-transferase Yfyf (Class Pi); Chain A, domain 2 › 0.57 40.0 3.83e-01 72.3% 79.3%
4gytA00 1.20.120.740 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › YgfB uncharacterised protein family PF03695 0.56 45.0 3.80e-01 87.1% 65.0%
2c41C01 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.56 43.0 3.85e-01 84.2% 90.6%
2chpA00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.56 43.0 3.84e-01 84.2% 91.9%
3au4A01 1.25.40.530 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › MyTH4 domain 0.55 40.0 3.33e-01 77.2% 60.7%
1f5oA00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.54 39.0 3.43e-01 75.2% 65.8%
3k3uA00 1.10.490.10 Mainly Alpha › Orthogonal Bundle › Globin-like › Globins 0.54 40.0 3.62e-01 77.2% 75.2%
6vvoE02 1.20.272.10 Mainly Alpha › Up-down Bundle › Zinc Finger, Delta Prime; domain 3 › 0.54 42.0 4.27e-01 86.1% 87.9%
2of7A02 1.10.357.10 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 0.53 41.0 3.79e-01 86.1% 87.9%
1sxjB03 1.20.272.10 Mainly Alpha › Up-down Bundle › Zinc Finger, Delta Prime; domain 3 › 0.53 38.0 4.01e-01 76.2% 87.0%
2gs4A00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.53 41.0 3.56e-01 83.2% 92.4%
1sxjE03 1.20.272.10 Mainly Alpha › Up-down Bundle › Zinc Finger, Delta Prime; domain 3 › 0.52 41.0 4.19e-01 86.1% 91.8%
2lyiA01 1.10.274.60 Mainly Alpha › Orthogonal Bundle › Enzyme I; Chain A, domain 2 › Spidroin, repetitive domain 0.52 46.0 4.08e-01 99.0% 86.5%
2prrA02 1.20.1290.10 Mainly Alpha › Up-down Bundle › AhpD-like › AhpD-like 0.51 36.0 3.40e-01 73.3% 98.4%
4usaA02 1.10.150.120 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › [2Fe-2S]-binding domain 0.51 38.0 3.67e-01 81.2% 98.3%
ECOD (35)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
5064030 182.1.3.0 alpha complex topology › Cryptochrome/photolyase FAD-binding domain-related › Cryptochrome/photolyase FAD-binding domain-related › PriX 0.88 77.0 7.91e-01 94.1% 97.9%
5081313 182.1.3.0 alpha complex topology › Cryptochrome/photolyase FAD-binding domain-related › Cryptochrome/photolyase FAD-binding domain-related › PriX 0.84 70.0 7.34e-01 98.0% 98.9%
3586830 182.1.3.2 alpha complex topology › Cryptochrome/photolyase FAD-binding domain-related › Cryptochrome/photolyase FAD-binding domain-related › PriX › PriCT_1 0.80 75.0 7.11e-01 100.0% 92.2%
4973692 182.1.3.0 alpha complex topology › Cryptochrome/photolyase FAD-binding domain-related › Cryptochrome/photolyase FAD-binding domain-related › PriX 0.77 66.0 6.68e-01 93.1% 100.0%
4942022 182.1.3.3 alpha complex topology › Cryptochrome/photolyase FAD-binding domain-related › Cryptochrome/photolyase FAD-binding domain-related › PriX › DNA_primase_lrg 0.77 71.0 6.70e-01 100.0% 91.7%
5030284 182.1.3.3 alpha complex topology › Cryptochrome/photolyase FAD-binding domain-related › Cryptochrome/photolyase FAD-binding domain-related › PriX › DNA_primase_lrg 0.76 70.0 6.61e-01 100.0% 99.2%
5054621 182.1.3.0 alpha complex topology › Cryptochrome/photolyase FAD-binding domain-related › Cryptochrome/photolyase FAD-binding domain-related › PriX 0.76 70.0 6.50e-01 100.0% 85.6%
4177876 182.1.3.0 alpha complex topology › Cryptochrome/photolyase FAD-binding domain-related › Cryptochrome/photolyase FAD-binding domain-related › PriX 0.74 65.0 6.48e-01 96.0% 97.1%
4997858 1075.1.2.0 alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › MacB transmembrane domain 0.71 51.0 4.29e-01 74.3% 91.8%
4935112 182.1.3.3 alpha complex topology › Cryptochrome/photolyase FAD-binding domain-related › Cryptochrome/photolyase FAD-binding domain-related › PriX › DNA_primase_lrg 0.68 61.0 5.77e-01 100.0% 91.7%
5057633 3651.1.1.0 alpha bundles › Translation initiation factor eIF-2B delta subunit N-terminal helical domain › Translation initiation factor eIF-2B delta subunit N-terminal helical domain › Translation initiation factor eIF-2B delta subunit N-terminal helical domain 0.68 49.0 4.69e-01 85.1% 66.1%
4676221 1188.1.1.3 alpha bundles › ZIP zinc transporter › ZIP zinc transporter › ZIP zinc transporter › Mntp 0.65 46.0 3.82e-01 74.3% 90.4%
3960566 4995.1.1.0 alpha arrays › Methionine synthase domain-like › Methionine synthase domain-like › Methionine synthase domain-like 0.65 44.0 4.51e-01 70.3% 87.0%
4992293 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.65 47.0 3.67e-01 75.2% 88.8%
3496275 109.4.1.594 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Syndetin_C 0.62 46.0 3.70e-01 78.2% 68.5%
4984499 1030.1.1.0 alpha duplicates or obligate multimers › Crispr-associated protein Csm2 › Crispr-associated protein Csm2 › Crispr-associated protein Csm2 0.61 42.0 3.99e-01 72.3% 93.6%
3587779 138.1.1.0 alpha arrays › DNA polymerase III clamp loader subunits, C-terminal domain › DNA polymerase III clamp loader subunits, C-terminal domain › DNA polymerase III clamp loader subunits, C-terminal domain 0.60 41.0 4.55e-01 85.1% 88.7%
3290087 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.60 45.0 3.61e-01 79.2% 90.2%
3877309 198.1.1.3 alpha arrays › Saposin-like › Saposin-like › Saposin-like › SapB_1 0.60 41.0 4.34e-01 71.3% 82.2%
3234110 2007.2.3.1 a/b three-layered sandwiches › Flavodoxin-like › Flavoproteins/Phosphotyrosine protein phosphatases-like › (Phosphotyrosine protein) phosphatases II › Y_phosphatase 0.58 41.0 3.35e-01 74.3% 37.9%
5029518 5060.2.1.0 alpha bundles › V-type ATP synthase subunit C › Toxin coregulated pilus biosynthesis protein E cytoplasmic domain › Toxin coregulated pilus biosynthesis protein E cytoplasmic domain 0.58 40.0 3.73e-01 72.3% 80.7%
3651618 109.4.1.425 alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › DUF707 0.57 41.0 3.21e-01 73.3% 37.6%
3838730 563.1.1.1 alpha bundles › ATPD N-terminal domain-like › N-terminal domain of the delta subunit of the F1F0-ATP synthase › N-terminal domain of the delta subunit of the F1F0-ATP synthase › OSCP 0.57 40.0 3.38e-01 73.3% 45.7%
5001604 5050.1.1.9 alpha complex topology › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › Major facilitator superfamily (MFS) general substrate transporter › MFS_1 0.57 40.0 3.23e-01 71.3% 91.5%
3972358 150.1.2.0 alpha bundles › Ferritin/Heme oxygenase/4-helical cytokines › Ferritin/Heme oxygenase › Heme oxygenase/Ribonucleotide reductase 0.56 47.0 3.49e-01 94.1% 96.1%
4968131 141.1.1.2 alpha bundles › Terpenoid synthases › Terpenoid synthases › Terpenoid synthases › SQS_PSY 0.56 44.0 3.09e-01 85.1% 26.8%
3282625 106.1.1.6 alpha arrays › Globin-like › Globin-like › Globin-like › MPAB_Lcp_cat 0.54 47.0 3.44e-01 100.0% 67.2%
3986130 2008.1.1.67 a/b three-layered sandwiches › Restriction endonuclease-like › Restriction endonuclease-like › Restriction endonuclease-like › RecC_C 0.53 39.0 2.80e-01 77.2% 72.3%
3391 138.1.1.11 alpha arrays › DNA polymerase III clamp loader subunits, C-terminal domain › DNA polymerase III clamp loader subunits, C-terminal domain › DNA polymerase III clamp loader subunits, C-terminal domain › RFC_C 0.53 41.0 4.19e-01 86.1% 89.9%
5001551 1075.1.2.1 alpha bundles › Type II ABC exporter transmembrane domain fold › Type II ABC exporter transmembrane domain-related › MacB transmembrane domain › FtsX 0.52 37.0 3.30e-01 77.2% 85.5%
3536908 5069.1.1.7 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › Cytochrom_B561 0.51 44.0 3.49e-01 100.0% 90.4%
3784891 3755.4.1.0 alpha bundles › YscO-like › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain › Phosphatidylinositol 3-kinase regulatory subunit inter-SH2 domain 0.51 36.0 3.32e-01 74.3% 96.4%
4289503 4002.1.1.5 alpha bundles › alpha-helical domain in dehydroquinate synthase-like enzymes › alpha-helical domain in dehydroquinate synthase-like enzymes › alpha-helical domain in dehydroquinate synthase-like enzymes › ADH_Fe_C 0.50 37.0 2.89e-01 77.2% 86.7%
4025777 138.1.1.4 alpha arrays › DNA polymerase III clamp loader subunits, C-terminal domain › DNA polymerase III clamp loader subunits, C-terminal domain › DNA polymerase III clamp loader subunits, C-terminal domain › MgsA_C 0.50 39.0 3.44e-01 87.1% 54.4%
3253771 4271.1.1.3 alpha complex topology › PriB N-terminal domain-like › PriB N-terminal domain-like › PriB N-terminal domain-like › DNA_primase_lrg_N 0.50 41.0 3.32e-01 96.0% 90.9%
D3 high residues 366-486
PDB
Domain cluster: representative
Pfam (1)
AccessionNameScoreE-valueQ covHMM cov
PF04104.20 best DNA_primase_lrg 27.8 3.00e-06 92.6% 42.8%
CATH (1)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
2liuA01 1.10.1200.10 Mainly Alpha › Orthogonal Bundle › Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A › ACP-like 0.53 35.0 4.06e-01 90.9% 96.5%
ECOD (16)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
4351550 182.1.2.1 alpha complex topology › Cryptochrome/photolyase FAD-binding domain-related › Cryptochrome/photolyase FAD-binding domain-related › Fe-S cluster domain of DNA primase › DNA_primase_lrg 0.90 79.0 7.07e-01 91.7% 100.0%
4942022 182.1.3.3 alpha complex topology › Cryptochrome/photolyase FAD-binding domain-related › Cryptochrome/photolyase FAD-binding domain-related › PriX › DNA_primase_lrg 0.86 73.0 7.41e-01 88.4% 100.0%
4103318 182.1.2.1 alpha complex topology › Cryptochrome/photolyase FAD-binding domain-related › Cryptochrome/photolyase FAD-binding domain-related › Fe-S cluster domain of DNA primase › DNA_primase_lrg 0.86 80.0 7.68e-01 98.3% 99.3%
5054621 182.1.3.0 alpha complex topology › Cryptochrome/photolyase FAD-binding domain-related › Cryptochrome/photolyase FAD-binding domain-related › PriX 0.85 75.0 7.46e-01 92.6% 100.0%
4494836 182.1.3.3 alpha complex topology › Cryptochrome/photolyase FAD-binding domain-related › Cryptochrome/photolyase FAD-binding domain-related › PriX › DNA_primase_lrg 0.85 77.0 7.54e-01 95.9% 96.9%
5068030 182.1.3.3 alpha complex topology › Cryptochrome/photolyase FAD-binding domain-related › Cryptochrome/photolyase FAD-binding domain-related › PriX › DNA_primase_lrg 0.84 73.0 7.35e-01 90.9% 100.0%
5030284 182.1.3.3 alpha complex topology › Cryptochrome/photolyase FAD-binding domain-related › Cryptochrome/photolyase FAD-binding domain-related › PriX › DNA_primase_lrg 0.84 66.0 6.64e-01 81.0% 100.0%
5058298 182.1.3.0 alpha complex topology › Cryptochrome/photolyase FAD-binding domain-related › Cryptochrome/photolyase FAD-binding domain-related › PriX 0.84 70.0 7.10e-01 86.8% 100.0%
4987601 182.1.3.3 alpha complex topology › Cryptochrome/photolyase FAD-binding domain-related › Cryptochrome/photolyase FAD-binding domain-related › PriX › DNA_primase_lrg 0.83 67.0 6.67e-01 83.5% 100.0%
5043574 182.1.3.3 alpha complex topology › Cryptochrome/photolyase FAD-binding domain-related › Cryptochrome/photolyase FAD-binding domain-related › PriX › DNA_primase_lrg 0.82 73.0 7.21e-01 93.4% 100.0%
3271098 182.1.2.1 alpha complex topology › Cryptochrome/photolyase FAD-binding domain-related › Cryptochrome/photolyase FAD-binding domain-related › Fe-S cluster domain of DNA primase › DNA_primase_lrg 0.81 76.0 6.26e-01 100.0% 98.5%
4935112 182.1.3.3 alpha complex topology › Cryptochrome/photolyase FAD-binding domain-related › Cryptochrome/photolyase FAD-binding domain-related › PriX › DNA_primase_lrg 0.80 67.0 6.73e-01 86.8% 98.3%
5057453 182.1.3.3 alpha complex topology › Cryptochrome/photolyase FAD-binding domain-related › Cryptochrome/photolyase FAD-binding domain-related › PriX › DNA_primase_lrg 0.80 70.0 6.92e-01 91.7% 92.0%
5064030 182.1.3.0 alpha complex topology › Cryptochrome/photolyase FAD-binding domain-related › Cryptochrome/photolyase FAD-binding domain-related › PriX 0.74 51.0 5.69e-01 71.1% 100.0%
3385990 101.1.6.4 alpha arrays › HTH › HTH › TrpR › Bac_DnaA_C 0.59 47.0 5.06e-01 90.9% 100.0%
4969724 187.1.1.0 alpha arrays › alpha-helical ferredoxin-like › alpha-helical ferredoxin › alpha-helical ferredoxin 0.50 34.0 3.37e-01 84.3% 64.0%
D4 medium residues 124-153_222-251
PDB
Domain cluster: representative
CATH (39)
Domain IDClass IDClassificationTM-scoreBitsE-valueQ covT cov
1bhaA00 1.10.287.170 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.82 43.0 4.16e-01 100.0% 47.8%
4nooB00 1.10.8.1160 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › 0.73 65.0 5.59e-01 100.0% 84.2%
6gwuD00 3.40.1050.10 Alpha Beta › 3-Layer(aba) Sandwich › Beta-carbonic Anhydrase; Chain A › Carbonic anhydrase 0.72 63.0 4.31e-01 96.7% 62.9%
1z0pA00 1.20.58.90 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.72 46.0 4.32e-01 71.7% 54.8%
2fcwA00 1.20.81.10 Mainly Alpha › Up-down Bundle › Receptor-associated Protein › RAP domain 0.71 52.0 4.21e-01 76.7% 48.1%
3bg2A03 1.10.3410.10 Mainly Alpha › Orthogonal Bundle › putative deoxyguanosinetriphosphate triphosphohydrolase fold › putative deoxyguanosinetriphosphate triphosphohydrolase like domain 0.70 54.0 4.52e-01 81.7% 64.6%
1xl3C00 1.20.1280.80 Mainly Alpha › Up-down Bundle › Monooxygenase › 0.70 49.0 4.18e-01 73.3% 84.6%
2aplA01 1.10.8.330 Mainly Alpha › Orthogonal Bundle › Helicase, Ruva Protein; domain 3 › PG0816-like 0.68 51.0 4.98e-01 83.3% 77.9%
1b3qA01 1.10.287.560 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Histidine kinase CheA-like, homodimeric domain 0.67 47.0 4.67e-01 78.3% 71.0%
3uo2B02 1.20.1280.20 Mainly Alpha › Up-down Bundle › Monooxygenase › HscB, C-terminal domain 0.67 46.0 4.07e-01 71.7% 54.8%
5kbwB00 1.10.1760.20 Mainly Alpha › Orthogonal Bundle › Arp2/3 complex 21 kDa subunit ARPC3 › 0.66 51.0 3.69e-01 85.0% 31.6%
2khmA01 1.10.10.1350 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Spidroin domain, C-terminal domain 0.65 49.0 4.07e-01 81.7% 50.9%
1fpoC02 1.20.1280.20 Mainly Alpha › Up-down Bundle › Monooxygenase › HscB, C-terminal domain 0.65 45.0 3.92e-01 73.3% 53.8%
4nqfA00 1.20.120.330 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 0.65 53.0 4.03e-01 91.7% 89.7%
3favD00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.64 49.0 4.51e-01 81.7% 83.3%
4dylA02 1.10.287.160 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › HR1 repeat 0.64 44.0 3.80e-01 71.7% 84.0%
2lm9A00 1.20.58.970 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.64 50.0 4.17e-01 81.7% 51.0%
1iuqA01 1.10.1200.50 Mainly Alpha › Orthogonal Bundle › Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein; Chain A › Glycerol-3-phosphate acyltransferase, alpha helical bundle, N-terminal 0.64 55.0 5.09e-01 96.7% 86.8%
1j30A00 1.20.1260.10 Mainly Alpha › Up-down Bundle › Ferritin › Ferritin, core subunit, four-helix bundle 0.64 49.0 3.66e-01 81.7% 34.8%
2yx8A00 1.10.150.510 Mainly Alpha › Orthogonal Bundle › DNA polymerase; domain 1 › Receptor activity modifying family 0.63 45.0 4.14e-01 76.7% 61.7%
4i0xG00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.63 48.0 4.66e-01 81.7% 79.4%
2q0yA01 3.40.630.30 Alpha Beta › 3-Layer(aba) Sandwich › Aminopeptidase › Gcn5-related N-acetyltransferase (GNAT) 0.60 41.0 3.24e-01 73.3% 31.2%
3c7jA02 1.20.120.530 Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › GntR ligand-binding domain-like 0.60 53.0 4.05e-01 100.0% 88.4%
2prrA02 1.20.1290.10 Mainly Alpha › Up-down Bundle › AhpD-like › AhpD-like 0.60 49.0 3.76e-01 86.7% 79.5%
2rd0B00 1.10.287.1490 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › 0.60 46.0 3.48e-01 81.7% 49.6%
6p73A02 1.20.140.10 Mainly Alpha › Up-down Bundle › Butyryl-CoA Dehydrogenase, subunit A; domain 3 › Butyryl-CoA Dehydrogenase, subunit A, domain 3 0.60 48.0 3.68e-01 90.0% 54.5%
2x2vA00 1.20.20.10 Mainly Alpha › Up-down Bundle › F1FO ATP Synthase › F1F0 ATP synthase subunit C 0.59 44.0 4.23e-01 80.0% 75.0%
1rtwB00 1.20.910.10 Mainly Alpha › Up-down Bundle › Heme Oxygenase; Chain A › Heme oxygenase-like 0.57 51.0 3.49e-01 100.0% 97.6%
1wa8A00 1.10.287.1060 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › ESAT-6-like 0.57 44.0 3.70e-01 83.3% 58.6%
4fqgB03 1.10.10.440 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › FF domain 0.56 39.0 3.88e-01 75.0% 72.7%
2l9bA00 1.25.40.630 Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › 0.56 38.0 3.39e-01 70.0% 52.7%
4q20A01 1.10.287.130 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Signal transduction histidine kinase, dimerisation/phosphotransfer (DHp) domain 0.56 45.0 3.96e-01 85.0% 64.6%
1gvnD00 3.40.50.300 Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases 0.54 44.0 2.94e-01 95.0% 25.2%
3euaA02 1.10.10.2240 Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › 0.53 37.0 3.66e-01 85.0% 68.8%
2fji101 1.10.357.50 Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › 0.53 48.0 3.25e-01 100.0% 52.6%
2bdeA03 1.20.58.1160 Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › 0.53 41.0 3.75e-01 83.3% 76.6%
1wpbG01 1.10.287.680 Mainly Alpha › Orthogonal Bundle › Helix Hairpins › Helix hairpin bin 0.52 38.0 3.95e-01 78.3% 94.4%
4x5mA00 1.20.1280.290 Mainly Alpha › Up-down Bundle › Monooxygenase › 0.51 45.0 4.02e-01 100.0% 82.6%
3bvoA02 1.20.1280.20 Mainly Alpha › Up-down Bundle › Monooxygenase › HscB, C-terminal domain 0.50 44.0 3.92e-01 98.3% 86.0%
ECOD (36)
UIDF-IDClassificationTM-scoreBitsE-valueQ covT cov
3649222 2004.1.1.23 a/b three-layered sandwiches › P-loop domains-like › P-loop domains-related › P-loop containing nucleoside triphosphate hydrolases › SNF2-rel_dom 0.73 56.0 3.40e-01 81.7% 14.6%
3947564 605.1.1.4 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase › HisKA_3 0.72 49.0 4.75e-01 70.0% 73.8%
5044572 310.2.1.0 a+b two layers › RRF/tRNA synthetase additional domain-like › Ribosome recycling factor, RRF › Ribosome recycling factor, RRF 0.72 50.0 4.07e-01 71.7% 54.3%
3999314 5058.1.1.35 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › EMC6 0.72 53.0 4.94e-01 80.0% 68.0%
4259375 192.7.1.2 alpha bundles › Long alpha-hairpin › tRNA-binding arm › tRNA-binding arm › Seryl_tRNA_N 0.70 47.0 3.79e-01 70.0% 40.9%
4937236 5058.1.1.0 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region 0.70 53.0 4.47e-01 81.7% 56.0%
3482882 5063.1.1.0 alpha bundles › Photosystem I reaction center subunit X, PsaK › Photosystem I reaction center subunit X, PsaK › Photosystem I reaction center subunit X, PsaK 0.69 55.0 5.57e-01 86.7% 90.0%
3559333 102.1.1.34 alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › SAM domain-like › SAM_4 0.69 50.0 4.44e-01 76.7% 90.6%
3935505 198.1.1.0 alpha arrays › Saposin-like › Saposin-like › Saposin-like 0.69 45.0 4.06e-01 80.0% 48.2%
5039692 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.69 53.0 4.49e-01 81.7% 54.7%
3588332 5069.1.1.23 alpha bundles › Transmembrane heme-binding four-helical bundle › Transmembrane heme-binding four-helical bundle › Transmembrane di-heme cytochromes › DUF2798 0.68 60.0 4.60e-01 100.0% 71.4%
3739839 5063.1.1.0 alpha bundles › Photosystem I reaction center subunit X, PsaK › Photosystem I reaction center subunit X, PsaK › Photosystem I reaction center subunit X, PsaK 0.67 56.0 4.59e-01 91.7% 82.7%
3721541 3291.1.1.0 alpha bundles › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related › Charged multivesicular body protein 3 (CHMP3)-related 0.67 50.0 4.27e-01 81.7% 54.0%
1068648 3720.1.1.1 alpha bundles › Receptor activity-modifying protein (RAMP) › Receptor activity-modifying protein (RAMP) › Receptor activity-modifying protein (RAMP) › RAMP 0.66 47.0 4.08e-01 75.0% 60.4%
3167271 192.8.1.385 alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain › Med11 0.66 49.0 4.43e-01 78.3% 76.2%
3455488 2006.1.4.0 a/b three-layered sandwiches › HAD domain-like › HAD domain-related › PIN domain-like 0.66 50.0 5.06e-01 83.3% 90.0%
5056304 5058.1.1.0 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region 0.64 49.0 4.05e-01 81.7% 57.1%
4946345 3684.1.1.0 alpha complex topology › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like › PSPTO4464 C-terminal domain-like 0.63 46.0 3.56e-01 78.3% 93.6%
4453951 632.11.1.0 alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like 0.63 52.0 5.11e-01 93.3% 100.0%
3386352 4207.1.1.104 alpha duplicates or obligate multimers › Mediator hinge subcomplex-like › Mediator hinge subcomplex-like › RNA polymerase II holoenzyme component SRB7 (MED21) › Bac_export_2 0.63 50.0 4.01e-01 85.0% 52.7%
4180835 5041.1.1.1 extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › ATP-synt_C 0.62 45.0 4.32e-01 78.3% 72.9%
3385570 5043.1.1.21 extended segments › Sensor proteins transmembrane domains › Htr2 transmembrane domain-like › Htr2 transmembrane domain-like › DUF2393 0.62 49.0 4.55e-01 85.0% 73.3%
4936252 5058.1.1.0 alpha bundles › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region › Mechanosensitive channel protein MscS (YggB), transmembrane region 0.62 48.0 4.08e-01 83.3% 56.8%
3598977 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.61 49.0 4.32e-01 85.0% 68.2%
4937556 5041.1.1.0 extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C 0.61 47.0 4.72e-01 85.0% 81.7%
3503989 162.1.1.1 alpha bundles › PTS-regulatory domain, PRD › PTS-regulatory domain, PRD › PTS-regulatory domain, PRD › PRD 0.60 45.0 3.94e-01 83.3% 54.7%
3961831 103.4.1.7 alpha arrays › RuvA-C › Elongation factor TFIIS domain 2/ Kix domain of creb binding protein › Elongation factor TFIIS domain 2/ Kix domain of creb binding protein › DUF1290 0.59 51.0 4.26e-01 96.7% 73.3%
4987541 611.8.1.0 alpha bundles › N-cbl like › C-terminal domain of E3 ubiquitin-protein ligase ARIH1 › C-terminal domain of E3 ubiquitin-protein ligase ARIH1 0.59 50.0 4.20e-01 100.0% 79.1%
3285528 192.29.1.53 alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) › DUF4328 0.59 53.0 3.64e-01 100.0% 30.3%
4051415 5041.1.1.1 extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › ATP-synt_C 0.58 42.0 3.78e-01 76.7% 58.8%
3624567 604.1.1.0 alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat 0.57 46.0 3.24e-01 85.0% 33.5%
4883675 5041.1.1.1 extended segments › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › F1F0 ATP synthase subunit C › ATP-synt_C 0.57 42.0 3.99e-01 80.0% 71.8%
3283686 605.1.1.0 alpha duplicates or obligate multimers › ROP-like › Homodimeric domain of signal transducing histidine kinase › Homodimeric domain of signal transducing histidine kinase 0.56 40.0 3.86e-01 76.7% 67.1%
3170575 3544.1.1.2 extended segments › Small envelope protein M › Small envelope protein M › Small envelope protein M › Pex24p 0.54 43.0 3.93e-01 83.3% 70.7%
3110288 192.8.1.0 alpha bundles › Long alpha-hairpin › Eukaryotic DNA topoisomerase I, dispensable insert domain › Eukaryotic DNA topoisomerase I, dispensable insert domain 0.53 42.0 3.91e-01 85.0% 97.4%
3252296 601.55.1.1 alpha bundles › Four-helical up-and-down bundle › anti-complement domain of BBK32 › anti-complement domain of BBK32 › NCA2 0.52 38.0 3.42e-01 85.0% 91.6%