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IMGVR_UViG_3300000032_000464-3300000032-Draft_004172011
Arc-VirIMGVR_UViG_3300000032_000464-3300000032-Draft_004172011
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 17-107
Domain cluster:
rep: IMGVR_UViG_3300000568_000486-3300000568-Draft_1017391213__D12-116
CATH (43)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 4nqfA00 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.70 | 63.0 | 5.36e-01 | 100.0% | 83.4% |
| 1wn0A00 | 1.20.120.160 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › HPT domain | 0.69 | 57.0 | 5.06e-01 | 100.0% | 62.6% |
| 2oznB01 | 1.20.1270.90 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › AF1782-like | 0.68 | 49.0 | 5.18e-01 | 75.8% | 93.8% |
| 2zxqA06 | 1.20.1270.70 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › Designed single chain three-helix bundle | 0.68 | 47.0 | 5.20e-01 | 90.1% | 98.5% |
| 1y4cA03 | 1.20.120.660 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › IL-4 antagonist (De novo design) like domain | 0.68 | 60.0 | 5.61e-01 | 100.0% | 86.7% |
| 3c18A02 | 1.20.120.330 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Nucleotidyltransferases domain 2 | 0.67 | 61.0 | 5.58e-01 | 100.0% | 84.7% |
| 2ewfA02 | 1.20.1270.310 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.67 | 51.0 | 5.32e-01 | 85.7% | 92.6% |
| 6gy8A01 | 1.20.1170.10 | Mainly Alpha › Up-down Bundle › Hemolysin E; Chain: A; › | 0.66 | 58.0 | 3.99e-01 | 100.0% | 73.5% |
| 2qkwA00 | 1.20.1270.140 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › AvrPto | 0.66 | 51.0 | 4.95e-01 | 83.5% | 98.0% |
| 1orjD00 | 1.20.120.340 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Flagellar protein FliS | 0.66 | 57.0 | 5.22e-01 | 100.0% | 80.0% |
| 4dmvA01 | 1.20.58.1190 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.65 | 44.0 | 4.59e-01 | 79.1% | 74.1% |
| 2qupA00 | 1.20.120.490 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Hypothetical protein TM1646-like domain | 0.65 | 57.0 | 5.26e-01 | 100.0% | 84.0% |
| 3ripA02 | 1.20.120.1900 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › Gamma-tubulin complex, C-terminal domain | 0.62 | 55.0 | 3.90e-01 | 97.8% | 70.6% |
| 4k0dA00 | 1.20.120.1730 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › | 0.62 | 54.0 | 4.74e-01 | 100.0% | 74.1% |
| 2ip6A00 | 1.20.1440.140 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › | 0.61 | 44.0 | 4.48e-01 | 78.0% | 79.3% |
| 2hujA00 | 1.20.120.440 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › YppE-like | 0.61 | 53.0 | 4.82e-01 | 100.0% | 88.0% |
| 1qv9A02 | 6.10.140.120 | Special › Helix non-globular › Helix Hairpins › | 0.61 | 45.0 | 4.39e-01 | 80.2% | 92.2% |
| 2x1dA02 | 1.10.10.2120 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › | 0.59 | 36.0 | 3.89e-01 | 86.8% | 74.3% |
| 2yfaA02 | 1.20.1440.210 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › | 0.59 | 43.0 | 4.00e-01 | 80.2% | 61.2% |
| 4dwlA00 | 1.20.1440.60 | Mainly Alpha › Up-down Bundle › de novo design (two linked rop proteins) › 23S rRNA-intervening sequence | 0.58 | 42.0 | 4.04e-01 | 78.0% | 66.7% |
| 1jnrA03 | 1.20.58.100 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain | 0.57 | 41.0 | 3.77e-01 | 75.8% | 67.8% |
| 3gi7A00 | 1.20.1270.180 | Mainly Alpha › Up-down Bundle › Substrate Binding Domain Of Dnak; Chain:A; Domain 2 › | 0.57 | 44.0 | 4.32e-01 | 85.7% | 93.2% |
| 2np3A00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.55 | 41.0 | 3.57e-01 | 79.1% | 81.7% |
| 1ho8A02 | 1.25.40.150 | Mainly Alpha › Alpha Horseshoe › Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat › V-type ATPase, subunit H, C-terminal domain | 0.55 | 38.0 | 3.56e-01 | 71.4% | 83.0% |
| 1jadA00 | 1.20.1230.10 | Mainly Alpha › Up-down Bundle › Phospholipase C Beta; Chain: A › Phospholipase C beta, distal C-terminal domain | 0.55 | 41.0 | 3.03e-01 | 79.1% | 79.8% |
| 3v9pB00 | 3.40.50.300 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › P-loop containing nucleotide triphosphate hydrolases | 0.55 | 42.0 | 3.31e-01 | 83.5% | 59.9% |
| 3edvB01 | 1.20.58.60 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.54 | 43.0 | 3.72e-01 | 83.5% | 64.0% |
| 6k9pB02 | 1.20.1300.20 | Mainly Alpha › Up-down Bundle › 3 helical TM bundles of succinate and fumarate reductases › Peptidase C65 Otubain, subdomain 2 | 0.54 | 45.0 | 3.92e-01 | 95.6% | 62.5% |
| 3vprA02 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.54 | 39.0 | 3.39e-01 | 76.9% | 84.8% |
| 7y3eA01 | 1.20.1530.20 | Mainly Alpha › Up-down Bundle › Na+/H+ antiporter like fold › | 0.54 | 46.0 | 3.07e-01 | 100.0% | 58.2% |
| 4kb2A01 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.53 | 41.0 | 3.88e-01 | 82.4% | 85.3% |
| 2oerA00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.53 | 40.0 | 3.26e-01 | 80.2% | 68.7% |
| 1br0A00 | 1.20.58.70 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.53 | 43.0 | 3.89e-01 | 85.7% | 80.8% |
| 4eqqA02 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.53 | 28.0 | 3.71e-01 | 86.8% | 97.9% |
| 1j8yF01 | 1.20.120.140 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › SRP54, nucleotide-binding domain | 0.53 | 43.0 | 4.43e-01 | 95.6% | 95.3% |
| 5jrcA00 | 1.20.58.2140 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › | 0.52 | 45.0 | 3.56e-01 | 94.5% | 47.3% |
| 1ls1A01 | 1.20.120.140 | Mainly Alpha › Up-down Bundle › Four Helix Bundle (Hemerythrin (Met), subunit A) › SRP54, nucleotide-binding domain | 0.52 | 42.0 | 4.24e-01 | 95.6% | 92.1% |
| 1q6aA00 | 1.10.1240.30 | Mainly Alpha › Orthogonal Bundle › Methyltransferase, Methionine Synthase (B12-binding Domains); Chain A, domain 1 › KaiA/RbsU domain | 0.51 | 38.0 | 3.62e-01 | 78.0% | 79.4% |
| 1wcrA00 | 1.20.58.80 | Mainly Alpha › Up-down Bundle › Methane Monooxygenase Hydroxylase; Chain G, domain 1 › Phosphotransferase system, lactose/cellobiose-type IIA subunit | 0.51 | 40.0 | 3.84e-01 | 83.5% | 78.6% |
| 1i5eA00 | 3.40.50.2020 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › | 0.51 | 43.0 | 3.35e-01 | 94.5% | 83.7% |
| 4l8iB00 | 1.10.132.20 | Mainly Alpha › Orthogonal Bundle › Topoisomerase I; Chain A, domain 4 › Ribosome-recycling factor | 0.51 | 39.0 | 3.68e-01 | 83.5% | 83.0% |
| 3e3vA01 | 1.10.10.10 | Mainly Alpha › Orthogonal Bundle › Arc Repressor Mutant, subunit A › Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain | 0.50 | 29.0 | 3.59e-01 | 85.7% | 96.2% |
| 3f1bA00 | 1.10.357.10 | Mainly Alpha › Orthogonal Bundle › Tetracycline Repressor; domain 2 › Tetracycline Repressor, domain 2 | 0.50 | 40.0 | 3.28e-01 | 89.0% | 84.7% |
ECOD (41)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3838012 | 601.1.2.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › I/LWEQ domain (Pfam 01608) | 0.77 | 59.0 | 5.29e-01 | 81.3% | 85.6% |
| 5018554 | 192.29.1.0 ↗ | alpha bundles › Long alpha-hairpin › bMERB domain (bivalent Mical/EHBP Rab binding) › bMERB domain (bivalent Mical/EHBP Rab binding) | 0.76 | 56.0 | 5.49e-01 | 78.0% | 100.0% |
| 4648665 | 632.7.1.1 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain › HSP70 | 0.76 | 57.0 | 5.85e-01 | 79.1% | 89.4% |
| 4367207 | 632.22.1.1 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats › EzrA | 0.74 | 54.0 | 5.19e-01 | 76.9% | 77.1% |
| 5066789 | 601.13.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Flagellar export chaperone FliS › Flagellar export chaperone FliS | 0.74 | 62.0 | 6.36e-01 | 98.9% | 98.8% |
| 4464616 | 632.7.1.1 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain › HSP70 | 0.73 | 55.0 | 5.59e-01 | 80.2% | 87.8% |
| 4216874 | 632.7.1.1 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Heat shock protein 70kD (HSP70), C-terminal subdomain › Heat shock protein 70kD (HSP70), C-terminal subdomain › HSP70 | 0.73 | 55.0 | 5.13e-01 | 80.2% | 67.8% |
| 3659174 | 138.1.1.0 ↗ | alpha arrays › DNA polymerase III clamp loader subunits, C-terminal domain › DNA polymerase III clamp loader subunits, C-terminal domain › DNA polymerase III clamp loader subunits, C-terminal domain | 0.73 | 60.0 | 5.86e-01 | 95.6% | 81.0% |
| 4367522 | 601.14.1.12 ↗ | alpha bundles › Four-helical up-and-down bundle › Hemerythrin › Hemerythrin › Rab3-GAP_cat_C | 0.71 | 63.0 | 5.26e-01 | 100.0% | 65.6% |
| 4428399 | 632.11.1.10 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › AF1782-like › AF1782-like › EzrA | 0.70 | 53.0 | 5.03e-01 | 81.3% | 80.0% |
| 5059791 | 601.7.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › HEPN › Nucleotidyltransferase substrate binding subunit/domain | 0.70 | 63.0 | 5.99e-01 | 100.0% | 95.2% |
| 5044962 | 632.22.1.0 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Cell division protein EzrA repeats › Cell division protein EzrA repeats | 0.70 | 53.0 | 5.24e-01 | 81.3% | 83.2% |
| 4041623 | 632.2.1.3 ↗ | alpha bundles › immunoglobulin/albumin-binding domain-like › Bacterial immunoglobulin/albumin-binding domains › Bacterial immunoglobulin/albumin-binding domains › FIVAR | 0.69 | 52.0 | 5.54e-01 | 80.2% | 97.3% |
| 4955871 | 102.1.3.0 ↗ | alpha arrays › HhH/H2TH › SAM/DNA-glycosylase › PAP/OAS1 substrate-binding domain | 0.69 | 61.0 | 5.89e-01 | 100.0% | 92.4% |
| 3931142 | 601.1.1.25 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin › GIT1_C | 0.68 | 61.0 | 5.69e-01 | 100.0% | 83.5% |
| 3414050 | 601.1.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › alpha-catenin-related › alpha-catenin/vinculin | 0.67 | 60.0 | 5.77e-01 | 100.0% | 86.7% |
| 3354384 | 601.3.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine-containing phosphotransfer domain, HPT domain › Histidine-containing phosphotransfer domain, HPT domain | 0.67 | 55.0 | 4.85e-01 | 100.0% | 60.7% |
| 4972788 | 601.2.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Cytochromes › Cytochromes | 0.65 | 57.0 | 5.41e-01 | 98.9% | 87.3% |
| 4988269 | 601.4.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › Histidine kinase associated sensor domains › Histidine kinase associated sensor domains | 0.62 | 55.0 | 5.45e-01 | 100.0% | 96.8% |
| 4315507 | 141.1.1.2 ↗ | alpha bundles › Terpenoid synthases › Terpenoid synthases › Terpenoid synthases › SQS_PSY | 0.62 | 48.0 | 3.26e-01 | 83.5% | 52.4% |
| 3597862 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.62 | 48.0 | 3.20e-01 | 83.5% | 56.8% |
| 5009775 | 601.33.1.0 ↗ | alpha bundles › Four-helical up-and-down bundle › CHAD domain › CHAD domain | 0.62 | 54.0 | 5.40e-01 | 100.0% | 97.9% |
| 5059491 | 633.23.1.0 ↗ | alpha bundles › Bromodomain-like › Claudin › Claudin | 0.61 | 45.0 | 3.59e-01 | 79.1% | 85.0% |
| 4646599 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.59 | 41.0 | 3.36e-01 | 72.5% | 47.4% |
| 3249930 | 5048.1.1.1 ↗ | alpha complex topology › Aquaporin-like › Aquaporin-like › Aquaporin-like › MIP | 0.58 | 49.0 | 3.65e-01 | 94.5% | 71.0% |
| 3814885 | 633.8.1.2 ↗ | alpha bundles › Bromodomain-like › MAST3 pre-PK domain-like › MAST3 pre-PK domain-like › PF26031 | 0.58 | 44.0 | 4.07e-01 | 81.3% | 69.2% |
| 3578428 | 5067.1.1.0 ↗ | alpha bundles › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain › Multidrug efflux transporter AcrB transmembrane domain | 0.57 | 40.0 | 3.45e-01 | 72.5% | 61.4% |
| 3177832 | 174.1.1.62 ↗ | few secondary structure elements › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › Tetraspanin transmembrane domain › PF27705 | 0.57 | 41.0 | 3.45e-01 | 75.8% | 46.3% |
| 4565296 | 109.4.1.934 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › HEAT_ATR | 0.57 | 41.0 | 3.07e-01 | 76.9% | 42.4% |
| 3230196 | 109.4.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat | 0.57 | 41.0 | 3.78e-01 | 80.2% | 58.3% |
| 4062922 | 140.1.1.4 ↗ | alpha bundles › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases › tRNA-synt_1e,DALR_2 | 0.56 | 44.0 | 3.93e-01 | 85.7% | 67.4% |
| 3397047 | 604.1.1.0 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat | 0.56 | 43.0 | 3.84e-01 | 80.2% | 80.8% |
| 3515125 | 3567.1.1.0 ↗ | a+b duplicates or obligate multimers › MPER trimer › MPER trimer › MPER trimer | 0.56 | 45.0 | 4.32e-01 | 100.0% | 75.5% |
| 3919843 | 604.1.1.124 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin_6 | 0.55 | 42.0 | 3.73e-01 | 80.2% | 80.0% |
| 5082352 | 109.3.1.0 ↗ | alpha superhelices › Repetitive alpha hairpins › Ankyrin repeat › Ankyrin repeat | 0.54 | 39.0 | 3.44e-01 | 76.9% | 78.6% |
| 4965582 | 4953.2.1.0 ↗ | beta barrels › L-aspartase C-terminal domain-like › Lid-like insertion of Propionyl-CoA synthase (PCS) ligase domain › Lid-like insertion of Propionyl-CoA synthase (PCS) ligase domain | 0.54 | 33.0 | 3.40e-01 | 78.0% | 62.2% |
| 4024445 | 3871.1.1.1 ↗ | alpha duplicates or obligate multimers › PHIST › PHIST › PHIST › PRESAN | 0.53 | 45.0 | 3.95e-01 | 95.6% | 87.1% |
| 3900969 | 604.1.1.1 ↗ | alpha bundles › Spectrin repeat-like › Spectrin repeat › Spectrin repeat › Spectrin | 0.53 | 37.0 | 3.46e-01 | 72.5% | 77.4% |
| 3514270 | 109.4.1.517 ↗ | alpha superhelices › Repetitive alpha hairpins › ARM repeat › ARM repeat › Med24_N | 0.52 | 36.0 | 3.18e-01 | 71.4% | 82.9% |
| 5065286 | 129.1.1.0 ↗ | alpha arrays › 6-phosphogluconate dehydrogenase C-terminal domain-like › 6-phosphogluconate dehydrogenase C-terminal domain-like › 6-phosphogluconate dehydrogenase C-terminal domain-like | 0.51 | 36.0 | 3.37e-01 | 72.5% | 80.7% |
| 4130802 | 181.1.1.1 ↗ | alpha bundles › Domain of the SRP/SRP receptor G proteins-like › Domain of the SRP/SRP receptor G-proteins › Domain of the SRP/SRP receptor G-proteins › SRP54_N | 0.51 | 39.0 | 4.05e-01 | 95.6% | 90.6% |