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IMGVR_UViG_3300000153_000446-3300000153-SI39nov09_135mDRAFT_10041404
Arc-VirIMGVR_UViG_3300000153_000446-3300000153-SI39nov09_135mDRAFT_10041404
3D Structure
Domains
high = three domain segmentations agree, medium = two domain segmentations agree. Numbered high-first then medium, N→C within each tier.
D1
high
residues 74-124
Domain cluster:
representative
Pfam (1)
| Accession | Name | Score | E-value | Q cov | HMM cov |
|---|---|---|---|---|---|
| PF10504.15 best | DUF2452 | 31.8 | 1.40e-07 | 100.0% | 32.0% |
CATH (47)
| Domain ID | Class ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 1yu0A02 | 2.80.20.10 | Mainly Beta › Trefoil › Tail fiber receptor-binding protein › Tail fiber receptor-binding protein | 0.76 | 66.0 | 4.80e-01 | 100.0% | 56.2% |
| 4q8gA00 | 3.90.70.10 | Alpha Beta › Alpha-Beta Complex › Cathepsin B; Chain A › Cysteine proteinases | 0.70 | 59.0 | 3.59e-01 | 96.1% | 47.4% |
| 2pnqA00 | 3.60.40.10 | Alpha Beta › 4-Layer Sandwich › Phosphatase 2c; domain 1 › PPM-type phosphatase domain | 0.70 | 56.0 | 3.32e-01 | 88.2% | 43.7% |
| 1iyjB03 | 2.40.50.140 | Mainly Beta › Beta Barrel › OB fold (Dihydrolipoamide Acetyltransferase, E2P) › Nucleic acid-binding proteins | 0.69 | 53.0 | 3.94e-01 | 88.2% | 41.5% |
| 3b5mA01 | 2.30.110.10 | Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A | 0.67 | 50.0 | 3.87e-01 | 82.4% | 72.3% |
| 1g2rA00 | 3.30.1230.10 | Alpha Beta › 2-Layer Sandwich › Hypothetical Cytosolic Protein; Chain: A; › YlxR-like | 0.66 | 46.0 | 3.85e-01 | 82.4% | 41.5% |
| 4pjeE01 | 2.60.40.10 | Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins | 0.65 | 50.0 | 4.05e-01 | 88.2% | 66.7% |
| 3etbL00 | 2.60.40.810 | Mainly Beta › Sandwich › Immunoglobulin-like › | 0.65 | 49.0 | 3.66e-01 | 86.3% | 61.5% |
| 4ktbA00 | 3.90.79.10 | Alpha Beta › Alpha-Beta Complex › Nucleoside Triphosphate Pyrophosphohydrolase › Nucleoside Triphosphate Pyrophosphohydrolase | 0.64 | 48.0 | 3.38e-01 | 80.4% | 68.1% |
| 1qr4A01 | 2.60.40.10 | Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins | 0.64 | 49.0 | 4.19e-01 | 86.3% | 62.1% |
| 7y8sB03 | 2.60.40.10 | Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins | 0.64 | 49.0 | 4.24e-01 | 86.3% | 65.5% |
| 2m2dA00 | 2.60.40.10 | Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins | 0.64 | 48.0 | 3.82e-01 | 86.3% | 64.4% |
| 5z06B02 | 2.60.40.10 | Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins | 0.63 | 48.0 | 4.06e-01 | 86.3% | 60.9% |
| 5a2fA01 | 2.60.40.10 | Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins | 0.63 | 47.0 | 3.86e-01 | 86.3% | 69.8% |
| 1uyvA01 | 3.90.226.10 | Alpha Beta › Alpha-Beta Complex › 2-enoyl-CoA Hydratase; Chain A, domain 1 › 2-enoyl-CoA Hydratase; Chain A, domain 1 | 0.62 | 48.0 | 3.12e-01 | 88.2% | 19.1% |
| 8shiI01 | 2.60.40.10 | Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins | 0.61 | 46.0 | 3.79e-01 | 86.3% | 76.0% |
| 2hhzA00 | 2.30.110.10 | Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A | 0.61 | 45.0 | 3.42e-01 | 84.3% | 76.8% |
| 2yn3B03 | 2.60.40.10 | Mainly Beta › Sandwich › Immunoglobulin-like › Immunoglobulins | 0.61 | 46.0 | 4.17e-01 | 86.3% | 60.6% |
| 2l6oA01 | 2.40.10.320 | Mainly Beta › Beta Barrel › Thrombin, subunit H › Uncharacterised protein PF13642 yp_926445, N-terminal domain | 0.59 | 43.0 | 3.87e-01 | 100.0% | 55.6% |
| 1o5lA00 | 2.60.120.10 | Mainly Beta › Sandwich › Jelly Rolls › Jelly Rolls | 0.59 | 40.0 | 3.01e-01 | 70.6% | 30.2% |
| 1ywlA00 | 3.40.1440.10 | Alpha Beta › 3-Layer(aba) Sandwich › GIY-YIG endonuclease › GIY-YIG endonuclease | 0.59 | 45.0 | 3.73e-01 | 86.3% | 87.5% |
| 4bt2A01 | 3.30.1330.80 | Alpha Beta › 2-Layer Sandwich › 60s Ribosomal Protein L30; Chain: A; › Hypothetical protein, similar to alpha- acetolactate decarboxylase; domain 2 | 0.58 | 38.0 | 3.03e-01 | 100.0% | 30.7% |
| 2eqkA01 | 2.30.30.140 | Mainly Beta › Roll › SH3 type barrels. › | 0.58 | 44.0 | 3.89e-01 | 100.0% | 56.2% |
| 3doaA03 | 3.40.970.40 | Alpha Beta › 3-Layer(aba) Sandwich › Ribonuclease HI; Chain A › fibrinogen binding protein from staphylococcus aureus domain like | 0.57 | 40.0 | 4.28e-01 | 76.5% | 90.7% |
| 4iajA00 | 3.30.1490.390 | Alpha Beta › 2-Layer Sandwich › Dna Ligase; domain 1 › Protein of unknown function DUF4649 | 0.57 | 44.0 | 3.96e-01 | 88.2% | 71.1% |
| 2nn6C00 | 3.30.230.70 | Alpha Beta › 2-Layer Sandwich › Ribosomal Protein S5; domain 2 › GHMP Kinase, N-terminal domain | 0.56 | 45.0 | 2.98e-01 | 100.0% | 77.0% |
| 4avaA01 | 2.60.120.10 | Mainly Beta › Sandwich › Jelly Rolls › Jelly Rolls | 0.54 | 36.0 | 2.75e-01 | 70.6% | 31.2% |
| 5mj6A03 | 2.60.40.1910 | Mainly Beta › Sandwich › Immunoglobulin-like › | 0.54 | 40.0 | 3.59e-01 | 84.3% | 61.3% |
| 3uh8A00 | 2.60.40.3350 | Mainly Beta › Sandwich › Immunoglobulin-like › | 0.54 | 39.0 | 3.18e-01 | 84.3% | 51.7% |
| 2imlA01 | 2.30.110.10 | Mainly Beta › Roll › Pnp Oxidase; Chain A › Electron Transport, Fmn-binding Protein; Chain A | 0.53 | 44.0 | 3.54e-01 | 100.0% | 66.4% |
| 2z04B03 | 3.30.470.20 | Alpha Beta › 2-Layer Sandwich › D-amino Acid Aminotransferase; Chain A, domain 1 › ATP-grasp fold, B domain | 0.53 | 40.0 | 2.80e-01 | 86.3% | 41.9% |
| 6b9tF01 | 2.60.120.10 | Mainly Beta › Sandwich › Jelly Rolls › Jelly Rolls | 0.53 | 46.0 | 3.50e-01 | 100.0% | 54.4% |
| 3szpB02 | 3.40.190.290 | Alpha Beta › 3-Layer(aba) Sandwich › D-Maltodextrin-Binding Protein; domain 2 › | 0.53 | 38.0 | 2.65e-01 | 82.4% | 35.2% |
| 4uzgA01 | 2.60.40.740 | Mainly Beta › Sandwich › Immunoglobulin-like › | 0.53 | 43.0 | 3.11e-01 | 94.1% | 84.6% |
| 2xjpA01 | 2.60.120.1560 | Mainly Beta › Sandwich › Jelly Rolls › | 0.52 | 40.0 | 2.70e-01 | 86.3% | 43.3% |
| 2f1eA00 | 2.60.40.1470 | Mainly Beta › Sandwich › Immunoglobulin-like › ApaG domain | 0.52 | 38.0 | 3.12e-01 | 86.3% | 59.5% |
| 2zuoA08 | 2.30.30.620 | Mainly Beta › Roll › SH3 type barrels. › | 0.52 | 39.0 | 3.76e-01 | 82.4% | 89.7% |
| 1plsA00 | 2.30.29.30 | Mainly Beta › Roll › PH-domain like › Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) | 0.52 | 37.0 | 2.98e-01 | 80.4% | 70.8% |
| 4pofA03 | 2.20.28.10 | Mainly Beta › Single Sheet › Rubrerythrin, domain 2 › | 0.51 | 35.0 | 3.61e-01 | 72.5% | 98.0% |
| 3teeA02 | 2.30.30.760 | Mainly Beta › Roll › SH3 type barrels. › | 0.51 | 37.0 | 3.38e-01 | 94.1% | 56.2% |
| 1d3bC00 | 2.30.30.100 | Mainly Beta › Roll › SH3 type barrels. › | 0.51 | 38.0 | 3.45e-01 | 82.4% | 85.9% |
| 4iauA01 | 2.60.20.10 | Mainly Beta › Sandwich › Gamma-B Crystallin; domain 1 › Crystallins | 0.51 | 40.0 | 3.52e-01 | 88.2% | 78.2% |
| 1fjmB00 | 3.60.21.10 | Alpha Beta › 4-Layer Sandwich › Purple Acid Phosphatase; chain A, domain 2 › Metallo-dependent phosphatases | 0.51 | 41.0 | 2.65e-01 | 96.1% | 84.1% |
| 1r17A02 | 2.60.40.1290 | Mainly Beta › Sandwich › Immunoglobulin-like › | 0.51 | 42.0 | 3.03e-01 | 96.1% | 60.1% |
| 4ebgA00 | 3.10.450.560 | Alpha Beta › Roll › Nuclear Transport Factor 2; Chain: A, › | 0.50 | 35.0 | 3.05e-01 | 80.4% | 93.8% |
| 2o2zA00 | 3.40.50.10680 | Alpha Beta › 3-Layer(aba) Sandwich › Rossmann fold › CofD-like domains | 0.50 | 36.0 | 2.36e-01 | 86.3% | 21.6% |
| 1fx0B01 | 2.40.10.170 | Mainly Beta › Beta Barrel › Thrombin, subunit H › | 0.50 | 44.0 | 3.82e-01 | 100.0% | 77.2% |
ECOD (41)
| UID | F-ID | Classification | TM-score | Bits | E-value | Q cov | T cov |
|---|---|---|---|---|---|---|---|
| 3277790 | 1.1.7.7 ↗ | beta barrels › cradle loop barrel › RIFT-related › Alanine racemase-C › FAD_binding_6 | 0.69 | 46.0 | 3.66e-01 | 70.6% | 62.9% |
| 5075125 | 11.1.1.0 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like | 0.67 | 52.0 | 4.26e-01 | 86.3% | 55.0% |
| 4026734 | 2003.1.5.73 ↗ | a/b three-layered sandwiches › Rossmann-like › Rossmann-related › S-adenosyl-L-methionine-dependent methyltransferases › Methyltransf_16 | 0.67 | 50.0 | 3.23e-01 | 82.4% | 45.1% |
| 3801339 | 7579.1.1.42 ↗ | a/b three-layered sandwiches › alpha/beta-Hydrolases › alpha/beta-Hydrolases › alpha/beta-Hydrolases › Hydrolase_4 | 0.67 | 53.0 | 3.28e-01 | 90.2% | 15.3% |
| 2754129 | 11.1.1.343 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › ScpA_C | 0.66 | 51.0 | 4.16e-01 | 88.2% | 63.1% |
| 1162196 | 11.1.1.99 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › V-set | 0.65 | 49.0 | 3.91e-01 | 86.3% | 63.5% |
| 3284431 | 862.1.1.5 ↗ | a+b complex topology › Prim-pol domain › Prim-pol domain › Prim-pol domain › LigD_Prim-Pol | 0.64 | 47.0 | 3.01e-01 | 84.3% | 59.4% |
| 3579804 | 11.1.1.0 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like | 0.64 | 49.0 | 3.99e-01 | 86.3% | 52.0% |
| 3881748 | 11.1.1.99 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › V-set | 0.64 | 48.0 | 3.74e-01 | 86.3% | 65.6% |
| 3417568 | 245.1.1.0 ↗ | a+b two layers › Ribonuclease PH domain 2-like › Ribonuclease PH domain 2 › Ribonuclease PH domain 2 | 0.63 | 48.0 | 3.91e-01 | 86.3% | 60.2% |
| 3251163 | 245.1.1.1 ↗ | a+b two layers › Ribonuclease PH domain 2-like › Ribonuclease PH domain 2 › Ribonuclease PH domain 2 › RNase_PH_C | 0.63 | 47.0 | 4.00e-01 | 84.3% | 50.0% |
| 3218175 | 245.1.1.1 ↗ | a+b two layers › Ribonuclease PH domain 2-like › Ribonuclease PH domain 2 › Ribonuclease PH domain 2 › RNase_PH_C | 0.63 | 47.0 | 4.01e-01 | 82.4% | 49.4% |
| 3312688 | 245.1.1.1 ↗ | a+b two layers › Ribonuclease PH domain 2-like › Ribonuclease PH domain 2 › Ribonuclease PH domain 2 › RNase_PH_C | 0.62 | 47.0 | 3.84e-01 | 86.3% | 60.0% |
| 3215161 | 11.1.1.0 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like | 0.62 | 41.0 | 3.59e-01 | 70.6% | 70.2% |
| 3240098 | 4184.1.1.0 ↗ | beta barrels › MFPT repeat › MFPT repeat › MFPT repeat | 0.61 | 50.0 | 4.00e-01 | 90.2% | 64.6% |
| 3907819 | 245.1.1.1 ↗ | a+b two layers › Ribonuclease PH domain 2-like › Ribonuclease PH domain 2 › Ribonuclease PH domain 2 › RNase_PH_C | 0.61 | 45.0 | 4.07e-01 | 86.3% | 56.2% |
| 3664232 | 12.5.1.14 ↗ | beta sandwiches › Glycosyl hydrolase domain-like › ZU5/Nup98-C/GAIN-B autoproteolytic domain-related › ZU5/Nup98-C/GAIN-B autoproteolytic domain-related › DUF1191 | 0.61 | 43.0 | 2.97e-01 | 78.4% | 22.1% |
| 4989054 | 11.1.1.0 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like | 0.60 | 45.0 | 3.83e-01 | 86.3% | 60.0% |
| 4215906 | 3578.1.1.1 ↗ | beta sandwiches › Third domain in metalloprotease StcE › Third domain in metalloprotease StcE › Third domain in metalloprotease StcE › TagA | 0.60 | 49.0 | 3.93e-01 | 94.1% | 54.3% |
| 3640834 | 245.1.1.0 ↗ | a+b two layers › Ribonuclease PH domain 2-like › Ribonuclease PH domain 2 › Ribonuclease PH domain 2 | 0.59 | 44.0 | 3.58e-01 | 86.3% | 39.8% |
| 4282521 | 11.1.1.652 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › Ribophorin_II_3rd | 0.58 | 44.0 | 3.37e-01 | 86.3% | 48.9% |
| 3225118 | 11.1.1.0 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like | 0.57 | 46.0 | 3.78e-01 | 92.2% | 64.3% |
| 5009968 | 11.1.4.0 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Prealbumin-like | 0.57 | 43.0 | 3.72e-01 | 84.3% | 62.4% |
| 3283905 | 70.1.1.0 ↗ | beta barrels › beta-clip › MoeA C-terminal domain-like › MoeA C-terminal domain-like | 0.57 | 47.0 | 4.38e-01 | 100.0% | 87.0% |
| 3734369 | 4121.1.1.0 ↗ | a+b three layers › CorA soluble domain-like › CorA soluble domain-like › CorA soluble domain-like | 0.56 | 43.0 | 2.71e-01 | 86.3% | 46.6% |
| 4958502 | 211.1.1.0 ↗ | a+b two layers › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase › Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase | 0.56 | 40.0 | 3.88e-01 | 86.3% | 66.2% |
| 3260566 | 11.1.1.0 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like | 0.56 | 42.0 | 3.46e-01 | 86.3% | 53.3% |
| 3344184 | 11.1.1.652 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like › Ribophorin_II_3rd | 0.56 | 41.0 | 3.13e-01 | 86.3% | 44.8% |
| 4423403 | 330.1.1.14 ↗ | a+b two layers › dsRBD-like › dsRNA-binding domain-like › dsRNA-binding domain-like › RecT | 0.55 | 43.0 | 3.16e-01 | 88.2% | 60.0% |
| 3415617 | 379.1.1.1 ↗ | few secondary structure elements › Kazal-type serine protease inhibitors-like › Kazal-type serine protease inhibitors › Kazal-type serine protease inhibitors › Kazal_1 | 0.55 | 39.0 | 3.99e-01 | 76.5% | 84.0% |
| 3275563 | 304.102.1.1 ↗ | a+b two layers › Alpha-beta plaits › Pseudouridine synthase › Pseudouridine synthase › PseudoU_synth_2 | 0.54 | 43.0 | 2.76e-01 | 94.1% | 32.3% |
| 3924183 | 11.1.1.0 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like | 0.54 | 41.0 | 3.60e-01 | 84.3% | 62.5% |
| 3503630 | 220.1.1.0 ↗ | beta barrels › PH domain-like › PH domain-like › PH domain-like | 0.53 | 38.0 | 3.18e-01 | 86.3% | 51.3% |
| 3507639 | 4.1.1.219 ↗ | beta barrels › SH3 › SH3 › SH3 › LSM12_LSM | 0.53 | 39.0 | 3.61e-01 | 82.4% | 81.4% |
| 4663567 | 207.6.1.12 ↗ | beta duplicates or obligate multimers › Single-stranded right-handed beta-helix › Serralysin-like metalloprotease-C › Serralysin-like metalloprotease-C › Ice_nucleation | 0.52 | 45.0 | 2.53e-01 | 100.0% | 9.7% |
| 3945230 | 7513.1.1.1 ↗ | a/b three-layered sandwiches › CofD-like › CofD-like › CofD-like › CofD | 0.52 | 43.0 | 2.66e-01 | 94.1% | 42.7% |
| 2543580 | 11.1.1.0 ↗ | beta sandwiches › Immunoglobulin-like beta-sandwich › Immunoglobulin-related › Immunoglobulin/Fibronectin type III/E set domains/PapD-like | 0.52 | 39.0 | 3.29e-01 | 86.3% | 53.1% |
| 164698 | 7513.1.1.1 ↗ | a/b three-layered sandwiches › CofD-like › CofD-like › CofD-like › CofD | 0.51 | 37.0 | 2.42e-01 | 88.2% | 49.4% |
| 3229463 | 269.1.1.9 ↗ | a+b complex topology › Fibrinogen C-terminal domain-like › Fibrinogen C-terminal domain-like › Fibrinogen C-terminal domain-like › PF29320 | 0.51 | 39.0 | 2.82e-01 | 88.2% | 31.9% |
| 4947996 | 2.1.1.0 ↗ | beta barrels › OB-fold › Nucleic acid-binding protein › Nucleic acid-binding protein | 0.50 | 38.0 | 3.74e-01 | 84.3% | 98.2% |
| 3718373 | 246.2.1.1 ↗ | a+b four layers › Carbon-nitrogen hydrolase-like › Metallo-dependent phosphatases › Metallo-dependent phosphatases › Metallophos | 0.50 | 41.0 | 2.56e-01 | 96.1% | 85.1% |